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Gene: Rhebl1 (RHEB like 1) Rattus norvegicus

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Symbol:

Rhebl1

Name:

RHEB like 1

RGD ID:

727778

Description:

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in TOR signaling and small GTPase-mediated signal transduction. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to human RHEBL1 (RHEB like 1); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

GTPase RhebL1; Ras homolog enriched in brain like 1; Ras homolog enriched in brain-like 1; ras homolog enriched in brain-like protein 1; rheb-like protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RHEBL1 (RHEB like 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Rhebl1 (Ras homolog enriched in brain like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rhebl1 (RHEB like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RHEBL1 (RHEB like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RHEBL1 (RHEB like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rhebl1 (RHEB like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RHEBL1 (RHEB like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RHEBL1 (RHEB like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rhebl1 (RHEB like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rhebl1 (RHEB like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Rhebl1 (Ras homolog enriched in brain like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RHEBL1 (RHEB like 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rhebl1 (Ras homolog, mTORC1 binding like 1)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	rhebl1 (Ras homolog, mTORC1 binding like 1)	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	RHB1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RHB1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Rheb	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Rheb	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	rheb-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rhebl1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,905,207 - 131,910,088 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	131,905,207 - 131,909,199 (-)	Ensembl				GRCr8
mRatBN7.2	7	130,026,255 - 130,031,127 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	130,026,341 - 130,030,248 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	131,833,475 - 131,837,459 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	134,059,035 - 134,063,019 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,971,548 - 133,975,532 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	140,552,704 - 140,556,980 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,552,733 - 140,556,639 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	115,063,060 - 115,066,994 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	137,645,541 - 137,649,476 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	126,515,270 - 126,519,209 (-)	NCBI		Celera
RGSC_v3.1	7	137,721,997 - 137,725,913 (-)	NCBI
Cytogenetic Map	7	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-palmitoylglycerol (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

butanal (ISO)

Butylbenzyl phthalate (EXP,ISO)

cadmium atom (ISO)

caffeine (EXP)

carbon nanotube (ISO)

choline (ISO)

chromium(6+) (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

ethyl methanesulfonate (ISO)

ferroheme b (ISO)

folic acid (ISO)

formaldehyde (ISO)

furan (EXP)

GSK-J4 (ISO)

heme b (ISO)

L-methionine (ISO)

lead diacetate (ISO)

methimazole (EXP)

methoxyacetic acid (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (EXP,ISO)

Monobutylphthalate (EXP)

nickel sulfate (ISO)

O-methyleugenol (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

tacrolimus hydrate (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of TORC1 signaling (IBA)

signal transduction (IEA)

small GTPase-mediated signal transduction (IBA)

TOR signaling (IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

endomembrane system (IEA)

membrane (IEA)

plasma membrane (IBA)

Molecular Function

GTP binding (IEA,ISO)

GTPase activity (IBA,IEA)

hydrolase activity (IEA)

metal ion binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein serine/threonine kinase activator activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Information Derived from GenBank Report	RGD, Sept. 2003

Additional References at PubMed

PMID:12869548	PMID:16328882

Genomics

Comparative Map Data

Rhebl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,905,207 - 131,910,088 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	131,905,207 - 131,909,199 (-)	Ensembl				GRCr8
mRatBN7.2	7	130,026,255 - 130,031,127 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	130,026,341 - 130,030,248 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	131,833,475 - 131,837,459 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	134,059,035 - 134,063,019 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,971,548 - 133,975,532 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	140,552,704 - 140,556,980 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,552,733 - 140,556,639 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	115,063,060 - 115,066,994 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	137,645,541 - 137,649,476 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	126,515,270 - 126,519,209 (-)	NCBI		Celera
RGSC_v3.1	7	137,721,997 - 137,725,913 (-)	NCBI
Cytogenetic Map	7	q36	NCBI

RHEBL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	49,064,676 - 49,069,979 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	49,064,676 - 49,070,039 (-)	Ensembl			hg38	GRCh38
GRCh37	12	49,458,459 - 49,463,762 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	47,744,735 - 47,750,042 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	47,744,734 - 47,750,042	NCBI
Celera	12	48,253,252 - 48,258,558 (-)	NCBI		Celera
Cytogenetic Map	12	q13.12	NCBI
HuRef	12	46,490,034 - 46,495,252 (-)	NCBI		HuRef
CHM1_1	12	49,424,262 - 49,429,533 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	49,026,849 - 49,032,153 (-)	NCBI		T2T-CHM13v2.0

Rhebl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	98,775,659 - 98,779,424 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	98,775,659 - 98,792,421 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	98,877,760 - 98,881,497 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	98,877,778 - 98,894,540 (-)	Ensembl			mm10	GRCm38
MGSCv37	15	98,708,191 - 98,711,845 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	98,705,812 - 98,709,448 (-)	NCBI		MGSCv36	mm8
Celera	15	101,027,359 - 101,031,015 (-)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	54.99	NCBI

Rhebl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955500	7,890,972 - 7,898,075 (-)	Ensembl
ChiLan1.0	NW_004955500	7,894,686 - 7,898,035 (-)	NCBI	ChiLan1.0	ChiLan1.0

RHEBL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	45,113,581 - 45,120,458 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	45,110,155 - 45,117,219 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	39,680,095 - 39,686,152 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	40,560,179 - 40,565,758 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	40,560,179 - 40,565,758 (+)	Ensembl			panPan2	panpan1.1

RHEBL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	5,509,640 - 5,512,893 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	5,509,874 - 5,512,909 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	40,744,670 - 40,747,938 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	5,560,701 - 5,563,966 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	5,560,697 - 5,563,973 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	5,524,700 - 5,527,961 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	5,514,664 - 5,517,922 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	41,137,008 - 41,140,275 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rhebl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	66,296,703 - 66,299,979 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	6,864,843 - 6,868,069 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	6,864,843 - 6,868,045 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RHEBL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	15,094,240 - 15,097,796 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	15,094,398 - 15,097,785 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	15,453,322 - 15,456,683 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RHEBL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	45,307,051 - 45,312,862 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	45,306,977 - 45,312,214 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	200,831,596 - 200,836,864 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rhebl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624816	3,121,850 - 3,125,267 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624816	3,121,657 - 3,125,530 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rhebl1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	271,699,198 - 271,702,992 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rhebl1
69 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	239
Count of miRNA genes:	168
Interacting mature miRNAs:	195
Transcripts:	ENSRNOT00000035659
Prediction methods:	Microtar, Miranda, Pita, Pita,Microtar, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
1354582	Stl11	Serum triglyceride level QTL 11	3.42		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	121393075	137014596	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	119280025	135560836	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	115313999	136544683	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	116269196	132020414	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	64	160	91	90	59	88	59	6	347	185	11	139	79	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_182825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001838701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010052989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC114446	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY327411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000089523 ⟹ ENSRNOP00000074953

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,905,207 - 131,909,191 (-)	Ensembl
mRatBN7.2 Ensembl	7	130,026,341 - 130,030,248 (-)	Ensembl
Rnor_6.0 Ensembl	7	140,552,733 - 140,556,639 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102528 ⟹ ENSRNOP00000091177

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,906,039 - 131,909,199 (-)	Ensembl
mRatBN7.2 Ensembl	7	130,027,087 - 130,030,248 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000133431 ⟹ ENSRNOP00000110629

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,905,207 - 131,907,944 (-)	Ensembl

RefSeq Acc Id:

NM_182825 ⟹ NP_877977

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,905,207 - 131,909,191 (-)	NCBI
mRatBN7.2	7	130,026,255 - 130,030,240 (-)	NCBI
Rnor_6.0	7	140,552,704 - 140,556,639 (-)	NCBI
Rnor_5.0	X	115,063,060 - 115,066,994 (-)	NCBI
RGSC_v3.4	7	137,645,541 - 137,649,476 (-)	RGD
Celera	7	126,515,270 - 126,519,209 (-)	RGD

Sequence:

show sequence

GCTGTGTTGTGATCACGTGGGCTGCCCGGGGCGCGCGGCTTGTTTTGGTTTTTCCTTGCGTTTG
CCGGGTGAGCTCCGGTGAGCTACTGTCCTTCCCCGTGTCCACCCAGGCCTGCACCTCGGCTGAT
CTTTGGGCTCCCTCAGCCCGCACTCTGACGAGCCCCGCGGGGCGGCGTCCTGTCATGCCGCTAG
TGCGCTACAGGAAGGTGGCCATCCTGGGGTACCGCTCCGTAGGGAAGACATCTTTGGCACATCA
ATTTGTGGAAGGGGAGTTCCTGAAAGGCTACGATCCTACAGTGGAGAATACTTACAGCAAGACA
GTGACTCTTGGCAAAGATGAGTTTCACCTACATCTAGTGGACACAGCAGGGCAGGATAAGTACA
GCATTCTGCCCTATTCCTTCATCATTGGGGTCCATGGTTACGTGCTTGTGTACAACGTTACCTC
CCTGCGCAGCTTCCAAATCGTTAAGAACCTGTACCAAAAGCTACAGGAAGGCCATGGTAAAACT
CGACTGCCAGTGCTGCTTGTGGGGAACAAGGCAGATCTCTCTGCAGACAGAGAGGTGCAGGCAG
TTGAAGGGAAGAAGCTAGCAGAGTCCTGGGGTGCAACATTTATGGAGTCATCTGCACGGGATAA
TCAGCTAATTCAGGACATCTTCATCAGAGTCATCCAGGAGATTGCCCGTGTGGAGAATTCTTAT
GGACAAGACCGCCGATGCTGTCTTATGTGAACTCTTGGCATGGAATAACTGCCCTGTTTCGGCC
ACAGGCATTGACCAACCTGCAGCAGTGGGGTCGACCCTCAGGACTTAAGTACTAGGGTTGCCAA
CTATGTCCTTACTCCTCTGGGCACACAGTAGGGGACCCTTATTTTTGCACACTCATCCCAGGTT
CTGGTAACCTGGATGTTAATGTTTACAAAGGGGCAAAACGTCTCAGGGACACTGGCTTCTAACT
CCTTGTTTTCCTAAACGAATTTTTATAGTCTGTACAGTTGGGATGAGTCTTGGGCATTGATTAC
CGAGGATCTGCCCTCCTGGGTATATTTTGGGTGTTGGTTGGGTAAGGGTGTTGGTCACTTGGCA
GTTCAGAAGTAGAACTGTCCGGGCTGGGGATTTAGCTCAGTGGTAGAGCGCTTACCTAGGAAGC
GCAAGGTCCTGGGTTCGGTACCCAGCTCCGAAAAAAAGACCCAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008765754 ⟹ XP_008763976

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,905,207 - 131,910,042 (-)	NCBI
mRatBN7.2	7	130,026,309 - 130,030,300 (-)	NCBI
Rnor_6.0	7	140,552,732 - 140,556,683 (-)	NCBI

Sequence:

show sequence

CCCTGCCCCCCCCCCCCCCGCGCTGGGCTCCCCTGCGTACAGCCGCTGTGTTGTGATCACGTGG
GCTGCCCGGGGCGCGCGGCTTGTTTTGGTTTTTCCTTGCGTTTGCCGGGTGAGCTCCGGTGAGC
TACTGTCCTTCCCCGTGTCCACCCAGGCCTGCACCTCGGCTGATCTTTGGGCTCCCTCAGCCCG
CACTCTGACGAGCCCCGCGGGGCGGCGTCCTGTCATGCCGCTAGTGCGCTACAGGAAGGTGGCC
ATCCTGGGGTACCGCTCCGTAGGGAAGACATCTTTGGCACATCAATTTGTGGAAGGGGAGTTCC
TGAAAGGCTACGATCCTACAGTGGAGAATACTTACAGCAAGACAGTGACTCTTGGCAAAGATGA
GTTTCACCTACATCTAGTGGACACAGCAGGGCAGGATAAGTACAGCATTCTGCCCTATTCCTTC
ATCATTGGGGTCCATGGTTACGTGCTTGTGTACAACGTTACCTCCCTGCGCAGCTTCCAAATCG
TTAAGAACCTGTACCAAAAGCTACAGGAAGGCCATGGTAAAACTCGACTGCCAGTGCTGCTTGT
GGGGAACAAGGCAGATCTCTCTGCAGACAGAGAGGTGCAGGCAGTTGAAGGGAAGAAGCTAGCA
GAGTCCTGGGGTGCAACATTTATGGAGTCATCTGCACGGGATAATCAGAGTCATCCAGGAGATT
GCCCGTGTGGAGAATTCTTATGGACAAGACCGCCGATGCTGTCTTATGTGAACTCTTGGCATGG
AATAACTGCCCTGTTTCGGCCACAGGCATTGACCAACCTGCAGCAGTGGGGTCGACCCTCAGGA
CTTAAGTACTAGGGTTGCCAACTATGTCCTTACTCCTCTGGGCACACAGTAGGGGACCCTTATT
TTTGCACACTCATCCCAGGTTCTGGTAACCTGGATGTTAATGTTTACAAAGGGGCAAAACGTCT
CAGGGACACTGGCTTCTAACTCCTTGTTTTCCTAAACGAATTTTTATAGTCTGTACAGTTGGGA
TGAGTCTTGGGCATTGATTACCGAGGATCTGCCCTCCTGGGTATATTTTGGGTGTTGGTTGGGT
AAGGGTGTTGGTCACTTGGCAGTTCAGAAGTAGAACTGTCCGGGCTGGGGATTTAGCTCAGTGG
TAGAGCGCTTACCTAGGAAGCGCAAGGTCCTGGGTTCGGTACCCAGCTCCGA

hide sequence

RefSeq Acc Id:

XM_008765755 ⟹ XP_008763977

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,905,691 - 131,910,054 (-)	NCBI
mRatBN7.2	7	130,026,737 - 130,030,304 (-)	NCBI
Rnor_6.0	7	140,553,178 - 140,556,684 (-)	NCBI

Sequence:

show sequence

CCCCTGCCCCCCCCCCCCCCGCGCTGGGCTCCCCTGCGTACAGCCGCTGTGTTGTGATCACGTG
GGCTGCCCGGGGCGCGCGGCTTGTTTTGGTTTTTCCTTGCGTTTGCCGGGTGAGCTCCGGTGAG
CTACTGTCCTTCCCCGTGTCCACCCAGGCCTGCACCTCGGCTGATCTTTGGGCTCCCTCAGCCC
GCACTCTGACGAGCCCCGCGGGGCGGCGTCCTGTCATGCCGCTAGTGCGCTACAGGAAGGTGGC
CATCCTGGGGTACCGCTCCGTAGGGAAGACATCTTTGGCACATCAATTTGTGGAAGGGGAGTTC
CTGAAAGGCTACGATCCTACAGTGGAGAATACTTACAGCAAGACAGTGACTCTTGGCAAAGATG
AGTTTCACCTACATCTAGTGGACACAGCAGGGCAGGATAAGTACAGCATTCTGCCCTATTCCTT
CATCATTGGGGTCCATGGTTACGTGCTTGTGTACAACGTTACCTCCCTGCGCAGCTTCCAAATC
GTTAAGAACCTGTACCAAAAGCTACAGGAAGGCCATGGTAAAACTCGACTGCCAGTGCTGCTTG
TGGGGAACAAGGCAGATCTCTCTGCAGACAGAGAGGTGCAGGCAGTTGAAGGGAAGAAGCTAGC
AGAGTCCTGGGGTGCAACATTTATGGAGTCATCTGCACGGGATAATCAGGTGCTCTAATTCAGG
ACATCTTCATCAGAGTCATCCAGGAGATTGCCCGTGTGGAGAATTCTTATGGACAAGACCGCCG
ATGCTGTCTTATGTGAACT

hide sequence

RefSeq Acc Id:

XM_039079358 ⟹ XP_038935286

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,905,207 - 131,910,055 (-)	NCBI
mRatBN7.2	7	130,026,309 - 130,030,315 (-)	NCBI

RefSeq Acc Id:

XM_039079359 ⟹ XP_038935287

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,905,207 - 131,910,061 (-)	NCBI
mRatBN7.2	7	130,026,309 - 130,030,308 (-)	NCBI

RefSeq Acc Id:

XR_010052989

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,905,812 - 131,910,088 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_877977	(Get FASTA)	NCBI Sequence Viewer
	XP_008763976	(Get FASTA)	NCBI Sequence Viewer
	XP_008763977	(Get FASTA)	NCBI Sequence Viewer
	XP_038935286	(Get FASTA)	NCBI Sequence Viewer
	XP_038935287	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAP92803	(Get FASTA)	NCBI Sequence Viewer
	EDL87019	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074953
	ENSRNOP00000074953.1
GenBank Protein	Q7TNZ5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_877977 ⟸ NM_182825
- UniProtKB:	Q7TNZ5 (UniProtKB/Swiss-Prot), A6KCC3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPLVRYRKVAILGYRSVGKTSLAHQFVEGEFLKGYDPTVENTYSKTVTLGKDEFHLHLVDTAGQ DKYSILPYSFIIGVHGYVLVYNVTSLRSFQIVKNLYQKLQEGHGKTRLPVLLVGNKADLSADRE VQAVEGKKLAESWGATFMESSARDNQLIQDIFIRVIQEIARVENSYGQDRRCCLM hide sequence

RefSeq Acc Id:

XP_008763976 ⟸ XM_008765754

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPLVRYRKVAILGYRSVGKTSLAHQFVEGEFLKGYDPTVENTYSKTVTLGKDEFHLHLVDTAGQ
DKYSILPYSFIIGVHGYVLVYNVTSLRSFQIVKNLYQKLQEGHGKTRLPVLLVGNKADLSADRE
VQAVEGKKLAESWGATFMESSARDNQSHPGDCPCGEFLWTRPPMLSYVNSWHGITALFRPQALT
NLQQWGRPSGLKY

hide sequence

RefSeq Acc Id:	XP_008763977 ⟸ XM_008765755
- Peptide Label:	isoform X4
- Sequence:	show sequence MPLVRYRKVAILGYRSVGKTSLAHQFVEGEFLKGYDPTVENTYSKTVTLGKDEFHLHLVDTAGQ DKYSILPYSFIIGVHGYVLVYNVTSLRSFQIVKNLYQKLQEGHGKTRLPVLLVGNKADLSADRE VQAVEGKKLAESWGATFMESSARDNQVL hide sequence

Ensembl Acc Id:

ENSRNOP00000074953 ⟸ ENSRNOT00000089523

RefSeq Acc Id:	XP_038935286 ⟸ XM_039079358
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038935287 ⟸ XM_039079359
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000091177 ⟸ ENSRNOT00000102528

Ensembl Acc Id:

ENSRNOP00000110629 ⟸ ENSRNOT00000133431

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7TNZ5-F1-model_v2	AlphaFold	Q7TNZ5	1-183	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727778	AgrOrtholog
BioCyc Gene	G2FUF-32107	BioCyc
Ensembl Genes	ENSRNOG00000054385	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000089523	ENTREZGENE
	ENSRNOT00000089523.2	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
InterPro	P-loop_NTPase	UniProtKB/Swiss-Prot
	Small_GTP-bd_dom	UniProtKB/Swiss-Prot
	Small_GTPase	UniProtKB/Swiss-Prot
	Small_GTPase_Ras-type	UniProtKB/Swiss-Prot
KEGG Report	rno:359959	UniProtKB/Swiss-Prot
NCBI Gene	359959	ENTREZGENE
PANTHER	PTHR24070	UniProtKB/Swiss-Prot
Pfam	Ras	UniProtKB/Swiss-Prot
PhenoGen	Rhebl1	PhenoGen
PRINTS	RASTRNSFRMNG	UniProtKB/Swiss-Prot
PROSITE	RAS	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000054385	RatGTEx
SMART	RAB	UniProtKB/Swiss-Prot
	RAS	UniProtKB/Swiss-Prot
	RHO	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
UniProt	A0A8I6AET4_RAT	UniProtKB/TrEMBL
	A0ABK0M612_RAT	UniProtKB/TrEMBL
	A6KCC3	ENTREZGENE, UniProtKB/TrEMBL
	Q7TNZ5	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-08-22	Rhebl1	RHEB like 1	Rhebl1	Ras homolog enriched in brain like 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Rhebl1	Ras homolog enriched in brain like 1		Ras homolog enriched in brain-like 1	Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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