Hs3st1 (heparan sulfate-glucosamine 3-sulfotransferase 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Hs3st1 (heparan sulfate-glucosamine 3-sulfotransferase 1) Rattus norvegicus
Analyze
Symbol: Hs3st1
Name: heparan sulfate-glucosamine 3-sulfotransferase 1
RGD ID: 71084
Description: Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase activity. Predicted to be involved in glycosaminoglycan biosynthetic process and heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Predicted to be active in Golgi apparatus. Orthologous to human HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1); PARTICIPATES IN heparan sulfate biosynthetic pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3OST-I; heparan sulfate (glucosamine) 3-O-sulfotransferase 1; heparan sulfate 3-O-sulfotransferase 1; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; heparan sulfate glucosamine 3-O-sulfotransferase 1; heparan sulfate glucosamine 3-O-sulfotransferase I
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81475,398,101 - 75,429,628 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1475,398,026 - 75,436,848 (+)EnsemblGRCr8
mRatBN7.21471,185,826 - 71,223,263 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1471,185,682 - 71,223,248 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1475,621,414 - 75,651,140 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01476,869,044 - 76,898,770 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01473,309,433 - 73,339,159 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01475,880,410 - 75,881,346 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1475,852,060 - 75,882,693 (+)Ensemblrn6Rnor6.0
Rnor_5.01475,872,397 - 75,873,333 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41476,438,219 - 76,439,157 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1470,167,035 - 70,167,971 (+)NCBICelera
RGSC_v3.11476,440,619 - 76,441,546 (+)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2,4-trimethylbenzene  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
corosolic acid  (ISO)
corticosterone  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cytarabine  (ISO)
DDE  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gentamycin  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
naphthalene  (ISO)
naphthalenes  (EXP)
nickel atom  (ISO)
okadaic acid  (ISO)
omega-6 fatty acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
phenylmercury acetate  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Golgi apparatus  (IEA,ISO)
Golgi lumen  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Expression of N-deacetylase/sulfotransferase and 3-O-sulfotransferase in rat alveolar type II cells. Li ZY, etal., Am J Physiol Lung Cell Mol Physiol 2000 Aug;279(2):L292-301.
4. Gene Data Set MGD Curation, June 12, 2002
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20500673  


Genomics

Comparative Map Data
Hs3st1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81475,398,101 - 75,429,628 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1475,398,026 - 75,436,848 (+)EnsemblGRCr8
mRatBN7.21471,185,826 - 71,223,263 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1471,185,682 - 71,223,248 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1475,621,414 - 75,651,140 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01476,869,044 - 76,898,770 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01473,309,433 - 73,339,159 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01475,880,410 - 75,881,346 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1475,852,060 - 75,882,693 (+)Ensemblrn6Rnor6.0
Rnor_5.01475,872,397 - 75,873,333 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41476,438,219 - 76,439,157 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1470,167,035 - 70,167,971 (+)NCBICelera
RGSC_v3.11476,440,619 - 76,441,546 (+)NCBI
Cytogenetic Map14q21NCBI
HS3ST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38411,393,150 - 11,434,327 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl411,393,150 - 11,429,564 (-)Ensemblhg38GRCh38
GRCh37411,394,774 - 11,430,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36411,009,086 - 11,039,635 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34411,076,256 - 11,106,806NCBI
Celera411,864,401 - 11,894,954 (-)NCBICelera
Cytogenetic Map4p15.33NCBI
HuRef410,732,784 - 10,763,337 (-)NCBIHuRef
CHM1_1411,398,055 - 11,428,601 (-)NCBICHM1_1
T2T-CHM13v2.0411,369,209 - 11,410,393 (-)NCBIT2T-CHM13v2.0
Hs3st1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39539,771,278 - 39,802,791 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl539,771,278 - 39,912,818 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38539,613,935 - 39,645,592 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl539,613,935 - 39,755,475 (-)Ensemblmm10GRCm38
MGSCv37540,005,174 - 40,035,870 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36539,902,184 - 40,043,724 (-)NCBIMGSCv36mm8
Celera537,077,022 - 37,107,666 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map521.14NCBI
Hs3st1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555491,591,605 - 1,623,681 (+)Ensembl
ChiLan1.0NW_0049555491,591,605 - 1,623,681 (+)NCBIChiLan1.0ChiLan1.0
HS3ST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2311,630,308 - 11,666,199 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1411,838,797 - 11,874,689 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v045,797,803 - 5,829,976 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1411,108,089 - 11,139,043 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl411,108,374 - 11,109,297 (-)EnsemblpanPan2panpan1.1
HS3ST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1368,306,512 - 68,336,879 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha370,831,990 - 70,862,330 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0368,922,300 - 68,952,641 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl368,950,937 - 68,951,854 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1368,330,085 - 68,360,403 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0368,492,806 - 68,523,133 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0368,864,624 - 68,894,997 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hs3st1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528561,974,067 - 62,004,935 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647715,676,178 - 15,706,067 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647715,676,151 - 15,706,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HS3ST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl87,389,780 - 7,423,869 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.187,389,774 - 7,424,558 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HS3ST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12738,683,032 - 38,716,222 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2738,714,570 - 38,715,493 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604785,456,975 - 85,489,159 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hs3st1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475520,035,055 - 20,039,967 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475520,010,126 - 20,039,988 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Hs3st1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11165,605,139 - 65,635,742 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hs3st1
94 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:25
Count of miRNA genes:24
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000014078
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat

Markers in Region
D5Wsu110e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21471,216,136 - 71,216,360 (+)MAPPERmRatBN7.2
Rnor_6.01475,881,538 - 75,881,761NCBIRnor6.0
Rnor_5.01475,873,525 - 75,873,748UniSTSRnor5.0
RGSC_v3.41476,439,347 - 76,439,570UniSTSRGSC3.4
Celera1470,168,163 - 70,168,386UniSTS
Cytogenetic Map14q21UniSTS
AA963021  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21471,215,924 - 71,216,143 (+)MAPPERmRatBN7.2
Rnor_6.01475,881,326 - 75,881,544NCBIRnor6.0
Rnor_5.01475,873,313 - 75,873,531UniSTSRnor5.0
RGSC_v3.41476,439,135 - 76,439,353UniSTSRGSC3.4
Celera1470,167,951 - 70,168,169UniSTS
Cytogenetic Map14q21UniSTS
Hs3st1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21471,215,206 - 71,215,411 (+)MAPPERmRatBN7.2
Rnor_6.01475,880,608 - 75,880,812NCBIRnor6.0
Rnor_5.01475,872,595 - 75,872,799UniSTSRnor5.0
Celera1470,167,233 - 70,167,437UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000014078   ⟹   ENSRNOP00000014077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1475,880,410 - 75,881,348 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000075975   ⟹   ENSRNOP00000068250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1475,405,457 - 75,429,631 (+)Ensembl
mRatBN7.2 Ensembl1471,214,565 - 71,216,419 (+)Ensembl
Rnor_6.0 Ensembl1475,852,060 - 75,882,693 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098441   ⟹   ENSRNOP00000091056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1475,398,151 - 75,436,848 (+)Ensembl
mRatBN7.2 Ensembl1471,186,469 - 71,223,248 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105004   ⟹   ENSRNOP00000094638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1475,398,026 - 75,436,848 (+)Ensembl
mRatBN7.2 Ensembl1471,185,682 - 71,223,248 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109235   ⟹   ENSRNOP00000081036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1471,207,136 - 71,223,248 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114048   ⟹   ENSRNOP00000082460
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1475,398,160 - 75,431,596 (+)Ensembl
mRatBN7.2 Ensembl1471,201,465 - 71,223,128 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114492   ⟹   ENSRNOP00000078209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1475,406,077 - 75,435,592 (+)Ensembl
mRatBN7.2 Ensembl1471,208,130 - 71,223,248 (+)Ensembl
RefSeq Acc Id: NM_053391   ⟹   NP_445843
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81475,398,973 - 75,428,701 (+)NCBI
mRatBN7.21471,186,637 - 71,216,365 (+)NCBI
Rnor_6.01475,880,410 - 75,881,346 (+)NCBI
Rnor_5.01475,872,397 - 75,873,333 (+)NCBI
RGSC_v3.41476,438,219 - 76,439,157 (+)RGD
Celera1470,167,035 - 70,167,971 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092506   ⟹   XP_038948434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81475,398,101 - 75,429,628 (+)NCBI
mRatBN7.21471,185,826 - 71,223,263 (+)NCBI
RefSeq Acc Id: XM_063273682   ⟹   XP_063129752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81475,398,153 - 75,429,628 (+)NCBI
Protein Sequences
Protein RefSeqs NP_445843 (Get FASTA)   NCBI Sequence Viewer  
  XP_038948434 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129752 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG09283 (Get FASTA)   NCBI Sequence Viewer  
  ASL70630 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000091056
  ENSRNOP00000094638
GenBank Protein Q9ESG5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445843   ⟸   NM_053391
- Peptide Label: precursor
- UniProtKB: G3V7E2 (UniProtKB/TrEMBL),   A6IJR8 (UniProtKB/TrEMBL),   A0A221CBA4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068250   ⟸   ENSRNOT00000075975
Ensembl Acc Id: ENSRNOP00000014077   ⟸   ENSRNOT00000014078
RefSeq Acc Id: XP_038948434   ⟸   XM_039092506
- Peptide Label: isoform X1
- UniProtKB: G3V7E2 (UniProtKB/TrEMBL),   A6IJR8 (UniProtKB/TrEMBL),   A0A221CBA4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000094638   ⟸   ENSRNOT00000105004
Ensembl Acc Id: ENSRNOP00000091056   ⟸   ENSRNOT00000098441
Ensembl Acc Id: ENSRNOP00000081036   ⟸   ENSRNOT00000109235
Ensembl Acc Id: ENSRNOP00000078209   ⟸   ENSRNOT00000114492
Ensembl Acc Id: ENSRNOP00000082460   ⟸   ENSRNOT00000114048
RefSeq Acc Id: XP_063129752   ⟸   XM_063273682
- Peptide Label: isoform X1
- UniProtKB: A6IJR8 (UniProtKB/TrEMBL),   G3V7E2 (UniProtKB/TrEMBL),   A0A221CBA4 (UniProtKB/TrEMBL)
Protein Domains
Sulfotransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ESG5-F1-model_v2 AlphaFold Q9ESG5 1-311 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71084 AgrOrtholog
BioCyc Gene G2FUF-15451 BioCyc
Ensembl Genes ENSRNOG00000010598 Ensembl
  ENSRNOG00000068537 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000098441 ENTREZGENE
  ENSRNOT00000105004 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
InterPro NST/OST UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Sulfotransferase_dom UniProtKB/Swiss-Prot
KEGG Report rno:84406 UniProtKB/Swiss-Prot
NCBI Gene 84406 ENTREZGENE
PANTHER HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 UniProtKB/Swiss-Prot
  PTHR10605 UniProtKB/Swiss-Prot
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot
PhenoGen Hs3st1 PhenoGen
RatGTEx ENSRNOG00000010598 RatGTEx
  ENSRNOG00000068537 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A221CBA4 ENTREZGENE, UniProtKB/TrEMBL
  A6IJR8 ENTREZGENE, UniProtKB/TrEMBL
  G3V7E2 ENTREZGENE, UniProtKB/TrEMBL
  HS3S1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Hs3st1  heparan sulfate-glucosamine 3-sulfotransferase 1  Hs3st1  heparan sulfate (glucosamine) 3-O-sulfotransferase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Hs3st1  heparan sulfate (glucosamine) 3-O-sulfotransferase 1      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in alveolar type II cells 70765