Nfya (nuclear transcription factor Y subunit alpha) - Rat Genome Database

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Gene: Nfya (nuclear transcription factor Y subunit alpha) Rattus norvegicus
Analyze
Symbol: Nfya
Name: nuclear transcription factor Y subunit alpha
RGD ID: 70976
Description: Enables transcription coregulator binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Part of CCAAT-binding activity factor complex. Orthologous to human NFYA (nuclear transcription factor Y subunit alpha); PARTICIPATES IN altered p53 signaling pathway; antigen processing and presentation pathway; tuberculosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CAAT box DNA-binding protein subunit A; CAAT-box DNA-binding protein subunit A; CBF-A; CBF-B; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; NF-YA; nuclear transcription factor Y subunit A; nuclear transcription factor-Y alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8920,085,067 - 20,111,521 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl920,085,073 - 20,111,504 (+)EnsemblGRCr8
mRatBN7.2912,587,437 - 12,613,911 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl912,586,259 - 12,613,898 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx921,100,678 - 21,124,947 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0926,166,902 - 26,191,171 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0924,549,971 - 24,574,266 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0914,551,752 - 14,577,002 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl914,551,758 - 14,576,967 (+)Ensemblrn6Rnor6.0
Rnor_5.0913,474,255 - 13,499,504 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.497,970,040 - 7,994,375 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera910,361,436 - 10,385,715 (+)NCBICelera
RGSC_v3.197,970,039 - 7,994,375 (+)NCBI
Cytogenetic Map9q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
coptisine  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
glycidyl methacrylate  (ISO)
hydrogen cyanide  (ISO)
L-ascorbic acid  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
monosodium L-glutamate  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel dichloride  (ISO)
nitrates  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
phenethyl caffeate  (EXP)
phenol  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium cyanide  (ISO)
quercetin  (ISO)
rifampicin  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trabectedin  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mutant p53: one name, many proteins. Freed-Pastor WA and Prives C, Genes Dev. 2012 Jun 15;26(12):1268-86. doi: 10.1101/gad.190678.112.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. NF-Y is essential for expression of the proapoptotic bim gene in sympathetic neurons. Hughes R, etal., Cell Death Differ. 2011 Jun;18(6):937-47. doi: 10.1038/cdd.2010.166. Epub 2010 Dec 17.
5. The B subunit of a rat heteromeric CCAAT-binding transcription factor shows a striking sequence identity with the yeast Hap2 transcription factor. Maity SN, etal., Proc Natl Acad Sci U S A 1990 Jul;87(14):5378-82.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. p53 mutations in cancer. Muller PA and Vousden KH, Nat Cell Biol. 2013 Jan;15(1):2-8. doi: 10.1038/ncb2641.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Interaction between the two ubiquitously expressed transcription factors NF-Y and Sp1. Roder K, etal., Gene. 1999 Jun 24;234(1):61-9.
13. Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3. Sinha S, etal., Proc Natl Acad Sci U S A 1995 Feb 28;92(5):1624-8.
Additional References at PubMed
PMID:1569083   PMID:1698608   PMID:8306889   PMID:11022037   PMID:11256944   PMID:12659851   PMID:12730328   PMID:15243141   PMID:15516209   PMID:15601870   PMID:15964792   PMID:16087680  
PMID:20630860   PMID:20861184   PMID:22969033   PMID:24030830  


Genomics

Comparative Map Data
Nfya
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8920,085,067 - 20,111,521 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl920,085,073 - 20,111,504 (+)EnsemblGRCr8
mRatBN7.2912,587,437 - 12,613,911 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl912,586,259 - 12,613,898 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx921,100,678 - 21,124,947 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0926,166,902 - 26,191,171 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0924,549,971 - 24,574,266 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0914,551,752 - 14,577,002 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl914,551,758 - 14,576,967 (+)Ensemblrn6Rnor6.0
Rnor_5.0913,474,255 - 13,499,504 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.497,970,040 - 7,994,375 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera910,361,436 - 10,385,715 (+)NCBICelera
RGSC_v3.197,970,039 - 7,994,375 (+)NCBI
Cytogenetic Map9q12NCBI
NFYA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38641,072,974 - 41,102,403 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl641,072,946 - 41,102,403 (+)Ensemblhg38GRCh38
GRCh37641,040,713 - 41,070,142 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36641,148,688 - 41,174,713 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34641,148,687 - 41,174,714NCBI
Celera642,593,388 - 42,622,828 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef640,758,459 - 40,787,895 (+)NCBIHuRef
CHM1_1641,043,210 - 41,072,650 (+)NCBICHM1_1
T2T-CHM13v2.0640,901,531 - 40,930,960 (+)NCBIT2T-CHM13v2.0
Nfya
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391748,693,917 - 48,716,782 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1748,693,913 - 48,716,934 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381748,386,885 - 48,409,820 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1748,386,885 - 48,409,906 (-)Ensemblmm10GRCm38
MGSCv371748,526,210 - 48,549,145 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361747,853,500 - 47,875,288 (-)NCBIMGSCv36mm8
Celera1751,818,370 - 51,841,444 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1723.99NCBI
Nfya
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554377,744,633 - 7,771,035 (+)Ensembl
ChiLan1.0NW_0049554377,745,182 - 7,770,348 (+)NCBIChiLan1.0ChiLan1.0
NFYA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2555,569,160 - 55,596,192 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1651,439,113 - 51,466,139 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0640,661,407 - 40,688,440 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1641,969,561 - 41,999,279 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl641,969,561 - 41,996,963 (+)EnsemblpanPan2panpan1.1
NFYA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1129,827,254 - 9,854,693 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl129,835,285 - 9,854,543 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha129,857,490 - 9,886,781 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01210,307,124 - 10,336,396 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1210,308,079 - 10,337,166 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1129,839,014 - 9,868,509 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0129,921,197 - 9,950,466 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01210,015,520 - 10,045,268 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nfya
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494645,209,288 - 45,233,519 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647618,725,907 - 18,750,864 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647618,728,575 - 18,750,917 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFYA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl736,385,873 - 36,409,488 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1736,385,677 - 36,409,495 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2741,682,169 - 41,705,576 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NFYA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11731,057,059 - 31,084,036 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1731,059,630 - 31,077,926 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604441,073,590 - 41,100,712 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfya
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475417,656,036 - 17,682,624 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475417,660,134 - 17,682,604 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Nfya
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1481,517,295 - 81,543,483 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nfya
256 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:42
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000017157
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9121707400Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)9131250552Rat
1578675Bss17Bone structure and strength QTL 173.8femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)9360535521031556Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)949664545496645Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9141763315Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9671488829567695Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)949664545496645Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)949664545496645Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat

Markers in Region
RH132935  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2912,586,272 - 12,586,470 (+)MAPPERmRatBN7.2
Rnor_6.0914,550,543 - 14,550,740NCBIRnor6.0
Rnor_5.0913,473,045 - 13,473,242UniSTSRnor5.0
RGSC_v3.497,968,825 - 7,969,022UniSTSRGSC3.4
Celera910,360,221 - 10,360,418UniSTS
RH 3.4 Map930.1UniSTS
Cytogenetic Map9q12UniSTS
RH94867  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2912,611,613 - 12,611,803 (+)MAPPERmRatBN7.2
Rnor_6.0914,574,704 - 14,574,893NCBIRnor6.0
Rnor_5.0913,497,206 - 13,497,395UniSTSRnor5.0
RGSC_v3.497,994,181 - 7,994,370UniSTSRGSC3.4
Celera910,385,521 - 10,385,710UniSTS
Cytogenetic Map9q12UniSTS
RH132381  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2912,611,580 - 12,611,789 (+)MAPPERmRatBN7.2
Rnor_6.0914,574,671 - 14,574,879NCBIRnor6.0
Rnor_5.0913,497,173 - 13,497,381UniSTSRnor5.0
RGSC_v3.497,994,148 - 7,994,356UniSTSRGSC3.4
Celera910,385,488 - 10,385,696UniSTS
RH 3.4 Map928.4UniSTS
Cytogenetic Map9q12UniSTS
RH94866  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2912,611,603 - 12,611,793 (+)MAPPERmRatBN7.2
Rnor_6.0914,574,694 - 14,574,883NCBIRnor6.0
Rnor_5.0913,497,196 - 13,497,385UniSTSRnor5.0
RGSC_v3.497,994,171 - 7,994,360UniSTSRGSC3.4
Celera910,385,511 - 10,385,700UniSTS
Cytogenetic Map9q12UniSTS
RH136693  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2912,588,286 - 12,588,409 (+)MAPPERmRatBN7.2
Rnor_6.0914,552,557 - 14,552,679NCBIRnor6.0
Rnor_5.0913,475,059 - 13,475,181UniSTSRnor5.0
RGSC_v3.497,970,839 - 7,970,961UniSTSRGSC3.4
Celera910,362,235 - 10,362,357UniSTS
Cytogenetic Map9q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017157   ⟹   ENSRNOP00000017157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl920,093,907 - 20,103,874 (+)Ensembl
mRatBN7.2 Ensembl912,596,294 - 12,606,263 (+)Ensembl
Rnor_6.0 Ensembl914,551,758 - 14,574,898 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091532   ⟹   ENSRNOP00000075707
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl920,085,077 - 20,111,504 (+)Ensembl
mRatBN7.2 Ensembl912,587,482 - 12,613,892 (+)Ensembl
Rnor_6.0 Ensembl914,560,504 - 14,576,967 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115817   ⟹   ENSRNOP00000078156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl920,085,073 - 20,111,504 (+)Ensembl
mRatBN7.2 Ensembl912,586,259 - 12,613,898 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000125437   ⟹   ENSRNOP00000112249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl920,093,306 - 20,111,504 (+)Ensembl
RefSeq Acc Id: NM_001413345   ⟹   NP_001400274
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,081 - 20,111,521 (+)NCBI
mRatBN7.2912,587,468 - 12,613,911 (+)NCBI
RefSeq Acc Id: NM_001413346   ⟹   NP_001400275
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,081 - 20,111,521 (+)NCBI
mRatBN7.2912,587,468 - 12,613,911 (+)NCBI
RefSeq Acc Id: NM_012865   ⟹   NP_036997
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,081 - 20,111,521 (+)NCBI
mRatBN7.2912,587,468 - 12,613,911 (+)NCBI
Rnor_6.0914,551,758 - 14,574,898 (+)NCBI
Rnor_5.0913,474,255 - 13,499,504 (+)NCBI
RGSC_v3.497,970,040 - 7,994,375 (+)RGD
Celera910,361,436 - 10,385,715 (+)RGD
Sequence:
RefSeq Acc Id: XM_006244410   ⟹   XP_006244472
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,067 - 20,111,518 (+)NCBI
mRatBN7.2912,587,437 - 12,611,589 (+)NCBI
Rnor_6.0914,551,753 - 14,577,002 (+)NCBI
Rnor_5.0913,474,255 - 13,499,504 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244411   ⟹   XP_006244473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,067 - 20,111,518 (+)NCBI
mRatBN7.2912,587,437 - 12,613,911 (+)NCBI
Rnor_6.0914,551,753 - 14,577,002 (+)NCBI
Rnor_5.0913,474,255 - 13,499,504 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244412   ⟹   XP_006244474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,067 - 20,111,518 (+)NCBI
mRatBN7.2912,587,437 - 12,613,911 (+)NCBI
Rnor_6.0914,551,753 - 14,577,002 (+)NCBI
Rnor_5.0913,474,255 - 13,499,504 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596305   ⟹   XP_017451794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,067 - 20,111,518 (+)NCBI
mRatBN7.2912,587,437 - 12,611,589 (+)NCBI
Rnor_6.0914,551,754 - 14,577,002 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063266814   ⟹   XP_063122884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,067 - 20,111,518 (+)NCBI
RefSeq Acc Id: XM_063266815   ⟹   XP_063122885
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,067 - 20,111,518 (+)NCBI
RefSeq Acc Id: XM_063266816   ⟹   XP_063122886
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,085,067 - 20,111,518 (+)NCBI
RefSeq Acc Id: NP_036997   ⟸   NM_012865
- Peptide Label: isoform 2
- UniProtKB: P18576 (UniProtKB/Swiss-Prot),   A0A8L2Q8B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244472   ⟸   XM_006244410
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y9Y4 (UniProtKB/TrEMBL),   A0A8L2Q8B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244473   ⟸   XM_006244411
- Peptide Label: isoform X2
- UniProtKB: A0A8L2Q8B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244474   ⟸   XM_006244412
- Peptide Label: isoform X3
- UniProtKB: A0A8L2Q8B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451794   ⟸   XM_017596305
- Peptide Label: isoform X7
- UniProtKB: A6JIF2 (UniProtKB/TrEMBL),   A0A8L2Q8B5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017157   ⟸   ENSRNOT00000017157
Ensembl Acc Id: ENSRNOP00000075707   ⟸   ENSRNOT00000091532
Ensembl Acc Id: ENSRNOP00000078156   ⟸   ENSRNOT00000115817
RefSeq Acc Id: NP_001400274   ⟸   NM_001413345
- Peptide Label: isoform 1
- UniProtKB: A0A8L2Q8B5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001400275   ⟸   NM_001413346
- Peptide Label: isoform 3
- UniProtKB: A0A0G2KB97 (UniProtKB/TrEMBL),   A0A8L2Q8B5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122885   ⟸   XM_063266815
- Peptide Label: isoform X5
- UniProtKB: A0A8L2Q8B5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122884   ⟸   XM_063266814
- Peptide Label: isoform X4
- UniProtKB: A6JIF1 (UniProtKB/TrEMBL),   A0A8L2Q8B5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122886   ⟸   XM_063266816
- Peptide Label: isoform X6
- UniProtKB: A0A8L2Q8B5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000112249   ⟸   ENSRNOT00000125437

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18576-F1-model_v2 AlphaFold P18576 1-341 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696488
Promoter ID:EPDNEW_R7013
Type:multiple initiation site
Name:Nfya_1
Description:nuclear transcription factor Y subunit alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0914,551,752 - 14,551,812EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70976 AgrOrtholog
BioCyc Gene G2FUF-28309 BioCyc
Ensembl Genes ENSRNOG00000012702 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000091532 ENTREZGENE
  ENSRNOT00000115817 ENTREZGENE
  ENSRNOT00000125437 ENTREZGENE
Gene3D-CATH 6.10.250.2430 UniProtKB/Swiss-Prot
InterPro CCAAT-binding_factor_CS UniProtKB/Swiss-Prot
  NFYA UniProtKB/Swiss-Prot
KEGG Report rno:29508 UniProtKB/Swiss-Prot
NCBI Gene 29508 ENTREZGENE
PANTHER PTHR12632 UniProtKB/Swiss-Prot
Pfam CBFB_NFYA UniProtKB/Swiss-Prot
PhenoGen Nfya PhenoGen
PRINTS CCAATSUBUNTB UniProtKB/Swiss-Prot
PROSITE NFYA_HAP2_1 UniProtKB/Swiss-Prot
  NFYA_HAP2_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012702 RatGTEx
SMART CBF UniProtKB/Swiss-Prot
UniProt A0A0G2KB97 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y9Y4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q8B5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M658_RAT UniProtKB/TrEMBL
  A6JIF1 ENTREZGENE, UniProtKB/TrEMBL
  A6JIF2 ENTREZGENE, UniProtKB/TrEMBL
  NFYA_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-20 Nfya  nuclear transcription factor Y subunit alpha  Nfya  nuclear transcription factor-Y alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Nfya  nuclear transcription factor-Y alpha      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function must heterodimerize with A component to be able to bind DNA 70612
gene_protein 341 amino acids 70612