Kif2a (kinesin family member 2A) - Rat Genome Database

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Pathways
Gene: Kif2a (kinesin family member 2A) Rattus norvegicus
Analyze
Symbol: Kif2a
Name: kinesin family member 2A
RGD ID: 70974
Description: Enables protein serine/threonine kinase binding activity. Involved in anterograde axonal transport. Predicted to be located in centriole and sperm principal piece. Predicted to be part of centriolar subdistal appendage and kinesin complex. Predicted to be active in GABA-ergic synapse; cytoplasm; and microtubule cytoskeleton. Predicted to colocalize with spindle microtubule and spindle pole. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 3. Orthologous to human KIF2A (kinesin family member 2A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Kif2; kinesin heavy chain family, member 2; kinesin heavy chain member 2; kinesin heavy chain member 2A; kinesin-2; kinesin-like protein KIF2A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8240,101,548 - 40,164,780 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl240,101,548 - 40,186,618 (-)EnsemblGRCr8
mRatBN7.2238,367,998 - 38,431,237 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl238,367,998 - 38,431,508 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx245,491,535 - 45,554,753 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0243,550,214 - 43,613,432 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0238,397,498 - 38,460,714 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0238,145,507 - 38,208,765 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl238,147,601 - 38,208,719 (-)Ensemblrn6Rnor6.0
Rnor_5.0257,240,240 - 57,302,984 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4238,079,564 - 38,143,398 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera234,235,756 - 34,298,829 (-)NCBICelera
RGSC_v3.1238,002,008 - 38,013,924 (-)NCBI
Cytogenetic Map2q13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon cytoplasm  (IEA)
centriolar subdistal appendage  (IEA,ISO)
centriole  (IEA,ISO)
centrosome  (IBA,IEA,ISO)
ciliary basal body  (IEA,ISO)
cytoplasm  (IBA,IEA,ISO)
dendrite  (IEA)
GABA-ergic synapse  (ISO)
kinesin complex  (IBA)
microtubule  (IBA,IEA,ISO)
mitotic spindle  (IEA,ISO)
nucleolus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
sperm principal piece  (ISO)
spindle  (IBA,IEA)
spindle microtubule  (IEA,ISO,ISS)
spindle pole  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Identification of a novel human kinesin-related gene (HK2) by the cDNA differential display technique. Debernardi S, etal., Genomics 1997 May 15;42(1):67-73.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KIF2 is a new microtubule-based anterograde motor that transports membranous organelles distinct from those carried by kinesin heavy chain or KIF3A/B. Noda Y, etal., J Cell Biol. 1995 Apr;129(1):157-67. doi: 10.1083/jcb.129.1.157.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation. Watanabe T, etal., J Cell Biol. 2015 Aug 31;210(5):737-51. doi: 10.1083/jcb.201412075.
Additional References at PubMed
PMID:12477932   PMID:15843429   PMID:17728463   PMID:18411309   PMID:19946888   PMID:21399614   PMID:23213374   PMID:24339785   PMID:29476059   PMID:30053369   PMID:31041455   PMID:31514228  


Genomics

Comparative Map Data
Kif2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8240,101,548 - 40,164,780 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl240,101,548 - 40,186,618 (-)EnsemblGRCr8
mRatBN7.2238,367,998 - 38,431,237 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl238,367,998 - 38,431,508 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx245,491,535 - 45,554,753 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0243,550,214 - 43,613,432 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0238,397,498 - 38,460,714 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0238,145,507 - 38,208,765 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl238,147,601 - 38,208,719 (-)Ensemblrn6Rnor6.0
Rnor_5.0257,240,240 - 57,302,984 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4238,079,564 - 38,143,398 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera234,235,756 - 34,298,829 (-)NCBICelera
RGSC_v3.1238,002,008 - 38,013,924 (-)NCBI
Cytogenetic Map2q13NCBI
KIF2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38562,306,206 - 62,391,025 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl562,306,162 - 62,391,025 (+)Ensemblhg38GRCh38
GRCh37561,602,033 - 61,686,852 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36561,637,746 - 61,717,967 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34561,678,712 - 61,717,967NCBI
Celera558,597,901 - 58,678,136 (+)NCBICelera
Cytogenetic Map5q12.1NCBI
HuRef558,558,087 - 58,639,465 (+)NCBIHuRef
CHM1_1561,601,610 - 61,682,674 (+)NCBICHM1_1
T2T-CHM13v2.0563,125,434 - 63,210,585 (+)NCBIT2T-CHM13v2.0
Kif2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913107,095,504 - 107,158,931 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13107,095,504 - 107,158,634 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3813106,958,996 - 107,022,355 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13106,958,996 - 107,022,126 (-)Ensemblmm10GRCm38
MGSCv3713107,750,665 - 107,812,194 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3613108,081,645 - 108,142,499 (-)NCBIMGSCv36mm8
Celera13111,296,434 - 111,357,980 (-)NCBICelera
Cytogenetic Map13D2.1NCBI
cM Map1358.06NCBI
Kif2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554466,244,547 - 6,279,089 (-)Ensembl
ChiLan1.0NW_0049554466,244,547 - 6,279,080 (-)NCBIChiLan1.0ChiLan1.0
KIF2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2451,526,263 - 51,606,649 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1549,679,897 - 49,760,283 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0551,605,954 - 51,690,921 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1553,251,415 - 53,332,218 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl553,251,415 - 53,332,218 (-)EnsemblpanPan2panpan1.1
KIF2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,642,961 - 48,715,605 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,645,380 - 48,714,025 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha245,653,412 - 45,726,282 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0249,120,201 - 49,193,369 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl249,123,873 - 49,194,809 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1246,189,037 - 46,262,137 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0246,976,421 - 47,049,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0247,832,428 - 47,905,530 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kif2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213197,386,873 - 197,421,209 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364806,324,216 - 6,357,741 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364806,324,214 - 6,357,696 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1641,016,674 - 41,102,545 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11641,016,680 - 41,101,122 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KIF2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1458,486,642 - 58,566,732 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl458,486,723 - 58,565,117 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660497,016,680 - 7,100,358 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kif2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248157,504,977 - 7,585,743 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248157,504,977 - 7,585,762 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Kif2a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13190,584,616 - 190,650,030 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Kif2a
519 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:138
Count of miRNA genes:67
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000019189, ENSRNOT00000019225
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2142977529Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
9590080Insglur4Insulin/glucose ratio QTL 428.70.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)2615276751152767Rat
1300160Hrtrt3Heart rate QTL 33.62heart pumping trait (VT:2000009)absolute change in heart rate (CMO:0000534)23561408353462005Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
731166Mamtr2Mammary tumor resistance QTL 20.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358154623581Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22888999173889991Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358144538110Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)2573632550736325Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)23326999678269996Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat

Markers in Region
RH132232  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2238,368,260 - 38,368,452 (+)MAPPERmRatBN7.2
Rnor_6.0238,145,770 - 38,145,961NCBIRnor6.0
Rnor_5.0257,240,503 - 57,240,694UniSTSRnor5.0
RGSC_v3.4238,079,827 - 38,080,018UniSTSRGSC3.4
Celera234,236,019 - 34,236,210UniSTS
RH 3.4 Map2177.2UniSTS
Cytogenetic Map2q14UniSTS
RH139596  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2238,367,968 - 38,368,164 (+)MAPPERmRatBN7.2
Rnor_6.0238,145,478 - 38,145,673NCBIRnor6.0
Rnor_5.0257,240,211 - 57,240,406UniSTSRnor5.0
RGSC_v3.4238,079,535 - 38,079,730UniSTSRGSC3.4
Celera234,235,727 - 34,235,922UniSTS
RH 3.4 Map2177.4UniSTS
Cytogenetic Map2q14UniSTS
RH140326  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2238,369,417 - 38,369,665 (+)MAPPERmRatBN7.2
Rnor_6.0238,146,927 - 38,147,174NCBIRnor6.0
Rnor_5.0257,241,660 - 57,241,907UniSTSRnor5.0
RGSC_v3.4238,080,984 - 38,081,231UniSTSRGSC3.4
Celera234,237,176 - 34,237,423UniSTS
RH 3.4 Map2179.4UniSTS
Cytogenetic Map2q14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000019189   ⟹   ENSRNOP00000019189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl240,101,548 - 40,164,933 (-)Ensembl
mRatBN7.2 Ensembl238,367,998 - 38,431,508 (-)Ensembl
Rnor_6.0 Ensembl238,147,601 - 38,208,719 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093988   ⟹   ENSRNOP00000095843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl240,101,548 - 40,186,618 (-)Ensembl
mRatBN7.2 Ensembl238,367,998 - 38,402,893 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000149313   ⟹   ENSRNOP00000103235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl240,101,548 - 40,164,354 (-)Ensembl
RefSeq Acc Id: NM_053376   ⟹   NP_445828
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8240,101,548 - 40,164,780 (-)NCBI
mRatBN7.2238,367,998 - 38,431,237 (-)NCBI
Rnor_6.0238,145,507 - 38,208,765 (-)NCBI
Rnor_5.0257,240,240 - 57,302,984 (-)NCBI
Celera234,235,756 - 34,298,829 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_445828 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD39241 (Get FASTA)   NCBI Sequence Viewer  
  AAH91304 (Get FASTA)   NCBI Sequence Viewer  
  EDM10287 (Get FASTA)   NCBI Sequence Viewer  
  EDM10288 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000095843
GenBank Protein Q9WV63 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445828   ⟸   NM_053376
- UniProtKB: Q9WV63 (UniProtKB/Swiss-Prot),   Q5BJW1 (UniProtKB/Swiss-Prot),   A6I5H9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019189   ⟸   ENSRNOT00000019189
Ensembl Acc Id: ENSRNOP00000095843   ⟸   ENSRNOT00000093988
Ensembl Acc Id: ENSRNOP00000103235   ⟸   ENSRNOT00000149313
Protein Domains
Kinesin motor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WV63-F1-model_v2 AlphaFold Q9WV63 1-705 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70974 AgrOrtholog
BioCyc Gene G2FUF-54524 BioCyc
Ensembl Genes ENSRNOG00000014000 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000093988 ENTREZGENE
Gene3D-CATH 3.40.850.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7310909 IMAGE-MGC_LOAD
InterPro KIF2A-like_N UniProtKB/Swiss-Prot
  Kinesin-like_fam UniProtKB/Swiss-Prot
  Kinesin_motor_CS UniProtKB/Swiss-Prot
  Kinesin_motor_dom UniProtKB/Swiss-Prot
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
MGC_CLONE MGC:109252 IMAGE-MGC_LOAD
NCBI Gene 84391 ENTREZGENE
PANTHER KINESIN-LIKE PROTEIN UniProtKB/Swiss-Prot
  KINESIN-RELATED PROTEIN 6 UniProtKB/Swiss-Prot
Pfam KIF2A-like_1st UniProtKB/Swiss-Prot
  Kinesin UniProtKB/Swiss-Prot
PhenoGen Kif2a PhenoGen
PRINTS KINESINHEAVY UniProtKB/Swiss-Prot
PROSITE KINESIN_MOTOR_1 UniProtKB/Swiss-Prot
  KINESIN_MOTOR_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014000 RatGTEx
SMART KISc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I6AU93_RAT UniProtKB/TrEMBL
  A0ABK0LMP0_RAT UniProtKB/TrEMBL
  A6I5H9 ENTREZGENE, UniProtKB/TrEMBL
  F1M8L1_RAT UniProtKB/TrEMBL
  KIF2A_RAT UniProtKB/Swiss-Prot
  Q5BJW1 ENTREZGENE
  Q9WV63 ENTREZGENE
UniProt Secondary Q5BJW1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-22 Kif2a  kinesin family member 2A  Kif2a  kinesin heavy chain member 2A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-29 Kif2a  kinesin heavy chain member 2A  Kif2a  kinesin family member 2A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Kif2a  kinesin family member 2A  Kif2  kinesin heavy chain family, member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Kif2  kinesin heavy chain family, member 2    kinesin heavy chain member 2  Name updated 1299863 APPROVED
2002-07-09 Kif2  kinesin heavy chain member 2      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function essential for the bipolarity of spindle assembly in cultured non-neuronal human, frog and hamster cells during mitosis 1358126
gene_function in mouse brain, involved in suppression of collateral branch extension during neuronal development, possibly by depolymerizing microtubules at the growth cone edge 1358127