Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Apoc4 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of APOC4 mRNA] | CTD | PMID:31150632 | Apoc4 | Rat | 1-naphthyl isothiocyanate | multiple interactions | ISO | APOC4 (Homo sapiens) | 6480464 | [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of APOC4 mRNA | CTD | PMID:27344345 | Apoc4 | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of APOC4 mRNA | CTD | PMID:17108234 | Apoc4 | Rat | 17beta-estradiol | increases expression | ISO | Apoc4 (Mus musculus) | 6480464 | Estradiol results in increased expression of APOC4 mRNA | CTD | PMID:39298647 | Apoc4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Apoc4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of APOC4 mRNA | CTD | PMID:21570461 | Apoc4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of APOC4 mRNA | CTD | PMID:21215274 | Apoc4 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of APOC4 mRNA | CTD | PMID:32109520 | Apoc4 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Apoc4 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of APOC4 mRNA | CTD | PMID:38648751 | Apoc4 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Apoc4 (Mus musculus) | 6480464 | bisphenol S results in increased expression of APOC4 mRNA | CTD | PMID:39298647 | Apoc4 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | APOC4 (Homo sapiens) | 6480464 | Fenretinide results in decreased expression of APOC4 mRNA | CTD | PMID:16671099 | Apoc4 | Rat | 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime | multiple interactions | ISO | APOC4 (Homo sapiens) | 6480464 | [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA | CTD | PMID:30611723 | Apoc4 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of APOC4 mRNA | CTD | PMID:24780913|PMID:25825206 | Apoc4 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of APOC4 mRNA | CTD | PMID:31881176 | Apoc4 | Rat | aflatoxin B1 | decreases expression | ISO | Apoc4 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of APOC4 mRNA | CTD | PMID:19770486 | Apoc4 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of APOC4 mRNA | CTD | PMID:16483693 | Apoc4 | Rat | benzo[a]pyrene | affects methylation | ISO | APOC4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of APOC4 promoter | CTD | PMID:27901495 | Apoc4 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of APOC4 mRNA | CTD | PMID:24768697|PMID:25181051 | Apoc4 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of APOC4 mRNA | CTD | PMID:32145629 | Apoc4 | Rat | bisphenol A | increases expression | ISO | Apoc4 (Mus musculus) | 6480464 | bisphenol A results in increased expression of APOC4 mRNA | CTD | PMID:30245210|PMID:33221593 | Apoc4 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of APOC4 mRNA | CTD | PMID:30903817 | Apoc4 | Rat | bisphenol A | increases expression | ISO | APOC4 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of APOC4 mRNA | CTD | PMID:29275510 | Apoc4 | Rat | bisphenol F | decreases expression | ISO | Apoc4 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of APOC4 mRNA | CTD | PMID:38685157 | Apoc4 | Rat | cadmium atom | multiple interactions | ISO | Apoc4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which affects the expression of APOC4 mRNA | CTD | PMID:37236586 | Apoc4 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of APOC4 promoter | CTD | PMID:22457795 | Apoc4 | Rat | cadmium dichloride | multiple interactions | ISO | Apoc4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which affects the expression of APOC4 mRNA | CTD | PMID:37236586 | Apoc4 | Rat | chenodeoxycholic acid | decreases expression | ISO | APOC4 (Homo sapiens) | 6480464 | Chenodeoxycholic Acid results in decreased expression of APOC4 mRNA | CTD | PMID:27174168 | Apoc4 | Rat | chlorpromazine | multiple interactions | ISO | APOC4 (Homo sapiens) | 6480464 | [Chlorpromazine co-treated with Cholic Acids] affects the expression of APOC4 mRNA | CTD | PMID:27344345 | Apoc4 | Rat | clofibrate | decreases expression | ISO | Apoc4 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of APOC4 mRNA | CTD | PMID:17585979 | Apoc4 | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of APOC4 mRNA | CTD | PMID:24386269 | Apoc4 | Rat | cyclosporin A | multiple interactions | ISO | APOC4 (Homo sapiens) | 6480464 | [Cyclosporine co-treated with Cholic Acids] affects the expression of APOC4 mRNA | CTD | PMID:27344345 | Apoc4 | Rat | decabromodiphenyl ether | multiple interactions | EXP | | 6480464 | [Flame Retardants co-treated with pentabromodiphenyl ether co-treated with decabromobiphenyl ether co-treated with hexabromocyclododecane] results in more ... | CTD | PMID:32207525 | Apoc4 | Rat | farnesol | decreases expression | ISO | APOC4 (Homo sapiens) | 6480464 | Farnesol analog results in decreased expression of APOC4 mRNA | CTD | PMID:30611723 | Apoc4 | Rat | fumonisin B1 | decreases expression | ISO | Apoc4 (Mus musculus) | 6480464 | fumonisin B1 results in decreased expression of APOC4 mRNA | CTD | PMID:16221962 | Apoc4 | Rat | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of APOC4 mRNA | CTD | PMID:25539665|PMID:26194646 | Apoc4 | Rat | GW 4064 | increases expression | ISO | APOC4 (Homo sapiens) | 6480464 | GW 4064 results in increased expression of APOC4 mRNA | CTD | PMID:30611723 | Apoc4 | Rat | GW 4064 | multiple interactions | ISO | APOC4 (Homo sapiens) | 6480464 | [GW 4064 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA | CTD | PMID:30611723 | Apoc4 | Rat | GW 7647 | multiple interactions | ISO | APOC4 (Homo sapiens) | 6480464 | [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA | CTD | PMID:30611723 | Apoc4 | Rat | GW 7647 | decreases expression | ISO | APOC4 (Homo sapiens) | 6480464 | GW 7647 results in decreased expression of APOC4 mRNA | CTD | PMID:30611723 | Apoc4 | Rat | lithocholic acid | decreases expression | ISO | Apoc4 (Mus musculus) | 6480464 | Lithocholic Acid results in decreased expression of APOC4 mRNA | CTD | PMID:20359477 | Apoc4 | Rat | methylmercury chloride | increases expression | ISO | APOC4 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of APOC4 mRNA | CTD | PMID:28001369 | Apoc4 | Rat | nitrofen | increases expression | EXP | | 6480464 | nitrofen results in increased expression of APOC4 mRNA | CTD | PMID:33484710 | Apoc4 | Rat | okadaic acid | decreases expression | ISO | APOC4 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of APOC4 mRNA | CTD | PMID:38832940 | Apoc4 | Rat | oleic acid | multiple interactions | ISO | APOC4 (Homo sapiens) | 6480464 | [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA; [GW 4064 more ... | CTD | PMID:30611723 | Apoc4 | Rat | paracetamol | affects expression | ISO | Apoc4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of APOC4 mRNA | CTD | PMID:17562736 | Apoc4 | Rat | paracetamol | decreases expression | ISO | APOC4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of APOC4 mRNA | CTD | PMID:26690555 | Apoc4 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Apoc4 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of APOC4 mRNA | CTD | PMID:37995155 | Apoc4 | Rat | perfluorooctanoic acid | affects expression | ISO | Apoc4 (Mus musculus) | 6480464 | perfluorooctanoic acid affects the expression of APOC4 mRNA | CTD | PMID:18281256 | Apoc4 | Rat | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of APOC4 mRNA | CTD | PMID:19162173 | Apoc4 | Rat | perfluorooctanoic acid | decreases expression | ISO | Apoc4 (Mus musculus) | 6480464 | perfluorooctanoic acid results in decreased expression of APOC4 mRNA | CTD | PMID:17681415 | Apoc4 | Rat | phenformin | increases expression | EXP | | 6480464 | Phenformin results in increased expression of APOC4 mRNA | CTD | PMID:31324951 | Apoc4 | Rat | phenobarbital | increases expression | ISO | APOC4 (Homo sapiens) | 6480464 | Phenobarbital results in increased expression of APOC4 protein | CTD | PMID:35881160 | Apoc4 | Rat | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of APOC4 mRNA | CTD | PMID:19162173 | Apoc4 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of APOC4 mRNA | CTD | PMID:19162173 | Apoc4 | Rat | progesterone | decreases expression | ISO | APOC4 (Homo sapiens) | 6480464 | Progesterone results in decreased expression of APOC4 mRNA | CTD | PMID:18037150 | Apoc4 | Rat | resveratrol | multiple interactions | ISO | APOC4 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of APOC4 mRNA | CTD | PMID:23557933 | Apoc4 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of APOC4 mRNA | CTD | PMID:28374803 | Apoc4 | Rat | sarin | increases expression | ISO | APOC4 (Homo sapiens) | 6480464 | Sarin results in increased expression of APOC4 mRNA | CTD | PMID:19522546 | Apoc4 | Rat | sodium arsenite | decreases expression | ISO | Apoc4 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of APOC4 mRNA | CTD | PMID:37682722 | Apoc4 | Rat | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of APOC4 mRNA | CTD | PMID:15963342 | Apoc4 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of APOC4 mRNA | CTD | PMID:31150632 | Apoc4 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of APOC4 mRNA] | CTD | PMID:31150632 | Apoc4 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of APOC4 mRNA | CTD | PMID:23411599|PMID:34492290 | Apoc4 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of APOC4 mRNA | CTD | PMID:33387578 | Apoc4 | Rat | valdecoxib | decreases expression | EXP | | 6480464 | valdecoxib results in decreased expression of APOC4 mRNA | CTD | PMID:24136188 | | 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