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Gene: Tinagl1 (tubulointerstitial nephritis antigen-like 1) Rattus norvegicus

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Symbol:

Tinagl1

Name:

tubulointerstitial nephritis antigen-like 1

RGD ID:

70956

Description:

Predicted to enable laminin binding activity. Predicted to be located in cytoplasm. Predicted to be active in extracellular space and lysosome. Orthologous to human TINAGL1 (tubulointerstitial nephritis antigen like 1); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

gis5; glucocorticoid-inducible protein; glucocorticoid-inducible protein 5; Lcn7; lipocalin 7; tubulointerstitial nephritis antigen-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	147,797,884 - 147,807,925 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	147,797,892 - 147,807,871 (-)	Ensembl				GRCr8
mRatBN7.2	5	142,513,710 - 142,523,730 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	142,513,714 - 142,523,720 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	145,214,476 - 145,223,855 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	146,984,290 - 146,993,669 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	146,981,656 - 146,991,034 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	148,382,702 - 148,392,729 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	148,382,706 - 148,392,697 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	152,101,199 - 152,111,202 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	149,198,274 - 149,207,653 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	140,981,392 - 140,990,771 (-)	NCBI		Celera
RGSC_v3.1	5	149,208,312 - 149,217,692 (-)	NCBI
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

1,2-dimethylhydrazine (ISO)

1,3,5-trinitro-1,3,5-triazinane (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-butoxyethanol (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

atrazine (EXP)

benzo[a]pyrene (EXP,ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butan-1-ol (ISO)

Butylbenzyl phthalate (EXP,ISO)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

carbon nanotube (ISO)

carnosic acid (ISO)

chloroprene (ISO)

copper(II) chloride (ISO)

corosolic acid (ISO)

corticosterone (EXP)

Cuprizon (EXP)

dexamethasone (EXP)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (EXP,ISO)

dioxygen (ISO)

doxorubicin (ISO)

endosulfan (EXP)

fenamidone (ISO)

fenthion (ISO)

fipronil (EXP)

folic acid (ISO)

gentamycin (EXP)

hydrogen sulfide (ISO)

isoprenaline (ISO)

lead diacetate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

Muraglitazar (EXP)

N,N-diethyl-m-toluamide (EXP)

N-methyl-N-nitrosourea (EXP)

N-Nitrosopyrrolidine (ISO)

naphthalene (ISO)

nicotine (ISO)

O-methyleugenol (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorooctanoic acid (EXP)

permethrin (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

serpentine asbestos (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

Tesaglitazar (EXP)

testosterone (EXP)

thalidomide (ISO)

titanium dioxide (ISO)

toluene (ISO)

triclosan (ISO)

tris(2-butoxyethyl) phosphate (ISO)

troglitazone (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteolysis (IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

extracellular region (IEA)

extracellular space (IBA)

lysosome (IBA)

Molecular Function

cysteine-type peptidase activity (IEA,ISO)

laminin binding (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Cloning, characterization, and expression of the human TIN-ag-RP gene encoding a novel putative extracellular matrix protein.	Bromme NC, etal., Biochem Biophys Res Commun 2000 May 10;271(2):474-80.
2.	Expression of genes involved in vascular development and angiogenesis in endothelial cells of adult lung.	Favre CJ, etal., Am J Physiol Heart Circ Physiol 2003 Nov;285(5):H1917-38. Epub 2003 Jul 3.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Isolation of an androgen-inducible novel lipocalin gene, Arg1, from androgen-dependent mouse mammary Shionogi carcinoma cells.	Kobayashi M, etal., J Steroid Biochem Mol Biol 2001 May;77(2-3):109-15.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	GOA pipeline	RGD automated data pipeline
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells.	Wex T, etal., Biochemistry 2001 Feb 6;40(5):1350-7.

Additional References at PubMed

PMID:12477932	PMID:19199708	PMID:19587330	PMID:20551380	PMID:23376485	PMID:23979707	PMID:24006456	PMID:27068509	PMID:27559042

Genomics

Comparative Map Data

Tinagl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	147,797,884 - 147,807,925 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	147,797,892 - 147,807,871 (-)	Ensembl				GRCr8
mRatBN7.2	5	142,513,710 - 142,523,730 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	142,513,714 - 142,523,720 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	145,214,476 - 145,223,855 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	146,984,290 - 146,993,669 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	146,981,656 - 146,991,034 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	148,382,702 - 148,392,729 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	148,382,706 - 148,392,697 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	152,101,199 - 152,111,202 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	149,198,274 - 149,207,653 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	140,981,392 - 140,990,771 (-)	NCBI		Celera
RGSC_v3.1	5	149,208,312 - 149,217,692 (-)	NCBI
Cytogenetic Map	5	q36	NCBI

TINAGL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	31,576,515 - 31,587,686 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	31,576,485 - 31,587,689 (+)	Ensembl			hg38	GRCh38
GRCh37	1	32,042,116 - 32,053,287 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	31,814,747 - 31,825,874 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	31,711,252 - 31,722,378	NCBI
Celera	1	30,311,348 - 30,322,513 (+)	NCBI		Celera
Cytogenetic Map	1	p35.2	NCBI
HuRef	1	30,159,667 - 30,170,714 (+)	NCBI		HuRef
CHM1_1	1	32,157,872 - 32,169,075 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	31,434,200 - 31,445,387 (+)	NCBI		T2T-CHM13v2.0

Tinagl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	130,059,393 - 130,068,915 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	130,058,247 - 130,068,915 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	130,165,600 - 130,175,122 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	130,164,454 - 130,175,122 (-)	Ensembl			mm10	GRCm38
MGSCv37	4	129,842,844 - 129,852,366 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	129,668,023 - 129,677,426 (-)	NCBI		MGSCv36	mm8
Celera	4	128,500,939 - 128,510,462 (-)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	63.43	NCBI

Tinagl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	9,995,902 - 10,007,445 (+)	Ensembl
ChiLan1.0	NW_004955452	9,995,658 - 10,007,418 (+)	NCBI	ChiLan1.0	ChiLan1.0

TINAGL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	195,244,699 - 195,255,858 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	194,363,492 - 194,374,657 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	30,857,700 - 30,868,861 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	31,878,090 - 31,888,934 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	31,878,090 - 31,888,934 (+)	Ensembl			panPan2	panpan1.1

TINAGL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	69,521,201 - 69,531,185 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	69,502,130 - 69,531,075 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	66,099,984 - 66,109,974 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	70,086,063 - 70,096,042 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	70,067,066 - 70,095,938 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	66,921,742 - 66,931,694 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	67,918,218 - 67,928,183 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	68,917,682 - 68,927,640 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tinagl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	48,879,812 - 48,889,359 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	14,704,570 - 14,714,139 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	14,704,401 - 14,714,110 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TINAGL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	88,095,672 - 88,112,761 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	88,095,650 - 88,106,092 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	81,806,767 - 81,821,190 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TINAGL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	101,284,761 - 101,295,511 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	101,285,350 - 101,294,857 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666033	15,395,459 - 15,406,744 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tinagl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	14,831,176 - 14,842,658 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624764	14,831,257 - 14,840,689 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tinagl1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	27,972,495 - 27,982,481 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tinagl1
61 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	82
Count of miRNA genes:	64
Interacting mature miRNAs:	76
Transcripts:	ENSRNOT00000018464
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	102105698	152749382	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	130249266	172190305	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	116702075	161702075	Rat
1354583	Despr3	Despair related QTL3	4.98	0.0002	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	5	132930505	172190305	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	141212838	172190305	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	134369218	156289444	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	133789363	172190305	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134369199	172190305	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136631198	172190305	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	112142946	157142946	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	112142946	157142946	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	110770739	155770739	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133081618	172190305	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138002522	170842766	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	112142946	157142946	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	133270647	172190305	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	141764300	172190305	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	133789363	172190305	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	111236572	156236572	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	131708216	172190305	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	114131300	159131300	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	125969677	156302135	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	112142946	157142946	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	116702075	161702075	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	112142946	157142946	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	116702075	161702075	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	74335621	156302135	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	116702075	161702075	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	114131300	159131300	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133081618	172190305	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	104262817	153890625	Rat

Markers in Region

D4Mit281

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	142,521,089 - 142,521,161 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	148,390,081 - 148,390,152	NCBI	Rnor6.0
Rnor_5.0	5	152,108,578 - 152,108,649	UniSTS	Rnor5.0
RGSC_v3.4	5	149,205,653 - 149,205,724	UniSTS	RGSC3.4
Celera	5	140,988,771 - 140,988,842	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH134342

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	156	91	90	59	80	59	6	344	180	11	135	81	92	31	13	13

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001433752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_053582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110893	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB050717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC097299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018464 ⟹ ENSRNOP00000018464

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	147,797,892 - 147,807,871 (-)	Ensembl
mRatBN7.2 Ensembl	5	142,513,714 - 142,523,720 (-)	Ensembl
Rnor_6.0 Ensembl	5	148,382,710 - 148,392,689 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000080166 ⟹ ENSRNOP00000071970

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	147,797,892 - 147,807,871 (-)	Ensembl
mRatBN7.2 Ensembl	5	142,513,714 - 142,523,720 (-)	Ensembl
Rnor_6.0 Ensembl	5	148,382,706 - 148,392,697 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093760 ⟹ ENSRNOP00000094381

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	147,797,892 - 147,807,871 (-)	Ensembl
mRatBN7.2 Ensembl	5	142,513,714 - 142,523,720 (-)	Ensembl

RefSeq Acc Id:

NM_053582 ⟹ NP_446034

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	147,797,884 - 147,807,263 (-)	NCBI
mRatBN7.2	5	142,513,710 - 142,523,090 (-)	NCBI
Rnor_6.0	5	148,382,702 - 148,392,081 (-)	NCBI
Rnor_5.0	5	152,101,199 - 152,111,202 (-)	NCBI
RGSC_v3.4	5	149,198,274 - 149,207,653 (-)	RGD
Celera	5	140,981,392 - 140,990,771 (-)	RGD

Sequence:

show sequence

CACCATGTGGGGATGTCCGCTAGGGCTGCTATTGCTGCTGCTGGCTGGCCAGGCTGCCCTGGAG
GCCCGGCGGAGTCGTTGGCGCAGGGAGCTGGCGCCAGGGCTGCACCTGCGGGGCATCCGGGACG
CCGGTGGCAGATACTGCCAAGAGCAGGACATGTGCTGCCGCGGCCGTGCTGACGAGTGTGCTTT
GCCCTACCTGGGAGCCACCTGTTACTGTGACCTCTTCTGCAACCGCACCGTCTCTGACTGCTGC
CCTGACTTTTGGGACTTCTGCCTCGGGATTCCACCCCCCTTCCCTCCTGTCCAAGGTTGCATGC
ATGCGGGCCGGATCTACCCAATCTTCGGAACCTATTGGGAAAACTGCAATCGGTGCACCTGCCA
TGAGAAAGGGCAGTGGGAATGTGACCAGGAGCCATGTCTAGTGGACCCAGCCATGATTAAAGCC
ATCAACCGGGGCAACTACGGGTGGCAGGCTGGGAACCACAGTGCCTTCTGGGGCATGACCCTGG
ATGAGGGCATTCGATACCGGCTGGGCACAATCCGCCCATCTTCCTCTGTCATGAATATGAATGA
AATTTATACAGTGCTGGGACAAGGAGAAGTGCTACCCACTGCCTTTGAGGCTTCCGAGAAGTGG
CCCAACCTGATCCATGAGCCGCTGGACCAGGGCAACTGTGCGGGTTCCTGGGCTTTCTCCACAG
CAGCTGTCGCATCTGACCGAGTGTCCATCCATTCTTTGGGACACATGACACCCATCCTCTCACC
GCAGAACCTGCTATCCTGTGATACCCACCACCAGAAGGGCTGCCGAGGTGGGCGTCTCGATGGT
GCTTGGTGGTTCCTGCGGCGCCGAGGGGTGGTGTCTGATAACTGTTACCCATTCTCCGGCCGTG
AGCAGAACGACGAGGCCAGCCCCACTCCTCGATGCATGATGCACAGCCGCGCCATGGGGCGGGG
CAAGCGCCAGGCCACTTCTCGCTGCCCCAATAGTCAGGTTGATTCCAATGACATCTACCAGGTC
ACGCCTGTCTACCGCCTGGCCTCCGATGAGAAGGAGATCATGAAGGAGCTAATGGAAAATGGCC
CCGTTCAAGCGCTTATGGAAGTACACGAAGACTTCTTCTTGTACCAGCGAGGCATCTACAGCCA
CACACCTGTAAGCCAGGGGAGGCCAGAGCAGTACCGCCGACACGGGACTCACTCTGTCAAGATC
ACAGGGTGGGGAGAAGAGACACTGCCAGACGGAAGGACGATCAAGTACTGGACTGCTGCCAACT
CGTGGGGCCCATGGTGGGGTGAGAGGGGCCACTTCCGAATCGTGCGTGGCATCAACGAGTGTGA
CATCGAGACCTTCGTGCTGGGCGTCTGGGGCCGCGTAGGAATGGAGGACATGGGGCACCACTGA
GTCTCGGCCACTAAGCTAGGTGGGATCCACAGCCACGGAAGAGGCCTTGGGGGCCACGCCGATG
AGGCCTTGGGACCAGGTGCTAATCCCCTCAGACTCAGATCCACACAAACGCAGAACCCCACCTG
GGAGCTAATGTCCCTCAGGGAGCAACAGTGAGGCTGGAGGGAACCCTCAGACATCACAGCCGGA
ACTGGAAAGGGCCCGGCTTGGAAACTGCAGGGAGTAAAATTCCCAGGCCCCTGGTCAGCCAGCC
CAAGACCATGGGAGCTAAGACACCCCAACCTCTTTATCCTCCTACCCAACCTCATTCTTATTTT
TTCATTCTCTTTGGTGGATTCTGCCCATCCCCCTGGCCTCCGTTCTGGCTGGACCTTTCCATCC
TCAACACTGCTTTCTTACTCTTTAAAAATATTTATTTTTCTTTTCATTAAAATAAAACCAAAGT
ATTGATAATTGC

hide sequence

RefSeq Acc Id:

XM_006238977 ⟹ XP_006239039

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	147,797,888 - 147,807,925 (-)	NCBI
mRatBN7.2	5	142,513,714 - 142,523,730 (-)	NCBI
Rnor_6.0	5	148,382,706 - 148,392,729 (-)	NCBI
Rnor_5.0	5	152,101,199 - 152,111,202 (-)	NCBI

Sequence:

show sequence

TCCCGCCCTGCGCTCCTCACTTGACTCGGTCTGGCAGTCTCGAGCTTGGAGGCGGAGGCGCGCA
GGGCAGCCTGGGTCCAGCCCACACCCCTCACCAGCAGGCACCATGTGGGGATGTCCGCTAGGGC
TGCTATTGCTGCTGCTGGCTGGCCAGGCTGCCCTGGAGGCCCGGCGGAGTCGTTGGCGCAGGGA
GCTGGCGCCAGGGCTGCACCTGCGGGGCATCCGGGACGCCGGTGGCAGATACTGCCAAGAGCAG
GACATGTGCTGCCGCGGCCGTGCTGACGAGTGTGCTTTGCCCTACCTGGGAGCCACCTGTTACT
GTGACCTCTTCTGCAACCGCACCGTCTCTGACTGCTGCCCTGACTTTTGGGACTTCTGCCTCGG
GATTCCACCCCCCTTCCCTCCTGTCCAAGGTTGCATGCATGCGGGCCGGATCTACCCAATCTTC
GGAACCTATTGGGAAAACTGCAATCGGTGCACCTGCCATGAGAAAGGGCAGTGGGAATGTGACC
AGGAGCCATGTCTAGTGGACCCAGCCATGATTAAAGCCATCAACCGGGGCAACTACGGGTGGCA
GGCTGGGAACCACAGTGCCTTCTGGGGCATGACCCTGGATGAGGGCATTCGATACCGGCTGGGC
ACAATCCGCCCATCTTCCTCTGTCATGAATATGAATGAGATTTATACGGTGCTGGGACAAGGAG
AAGTGCTACCCACTGCCTTTGAGGCTTCCGAGAAGTGGCCCAACCTGATCCATGAGCCGCTGGA
CCAGGGCAACTGTGCGGGTTCCTGGGCCTTCTCCACAGCAGCTGTCGCATCTGACCGAGTGTCC
ATCCATTCTTTGGGACACATGACACCCATCCTCTCACCGCAGAACCTGCTATCCTGTGATACCC
ACCACCAGAAGGGCTGCCGAGGTGGGCGTCTCGATGGTGCTTGGTGGTTCCTGCGGTGCCGAGG
GGTGGTGTCTGATAACTGTTACCCATTCTCCGGCCGTGAGCAGAACGACGAGGCCAGCCCCACT
CCTCGATGCATGATGCACAGCCGCGCCATGGGGCGGGGCAAGCGCCAGGCCACTTCTCGCTGCC
CCAATAGTCATGTTGATTCCAATGACATCTACCAGGTCACGCCTGTCTACCGCCTGGCCTCCGA
TGAGAAGGAGATCATGAAGGAGCTAATGGAAAATGGCCCTGTTCAAGCGCTTATGGAAGTACAC
GAAGACTTCTTCTTGTACCAGCGAGGCATCTACAGCCACACACCTGTAAGCCAGGGGAGGCCAG
AGCAGTACCGCCGACACGGGACTCACTCTGTCAAGATCACAGGGTGGGGAGAAGAGACACTGCC
AGACGGAAGGACGATCAAGTACTGGACTGCTGCCAACTCGTGGGGCCCATGGTGGGGTGAGAGG
GGCCACTTCCGAATCGTGCGTGGCACCAACGAGTGTGACATCGAGACCTTCGTGCTGGGCGTCT
GGGGCCGAGTAGGAATGGAGGACATGGGGCACCACTGAGTCTCGGCCACTAAGCTAGGTGGGAT
CCACAGCCACAGAAGAGGCCTTGGGGGCCACGCCGATGAGGCCTTGGGACCAGGTGCTAATCCC
CTCAGACTCAGATCCACACAAACGCAGAACCCCACCTGGGAGCTAATGTCCCTCAGGGAGCAAC
AGTGAGGCTGGAGGGAACCCTCAGACATCACAGCCGGAACTGGAAAGGGCCCGGCTTGGAAACT
GCAGGGAGTAAAATTCCCAGGCCCCTGGTCAGCCAGCCCAAGACCATGGGAGCTAAGACACCCC
AACCTCTTCATCCTCCTACCCAACCTCATTCTTATTTTTTCATTCTCCTTGGTGGATTCTGCCC
ATCCCCCTGGCCTCCGTTCTGGCTGGACCTTTCCATCCTCAACACTGCTTTCTTACTCTTTAAA
AATATTTATTTTTCTTTTCATTAAAATAAAACCAAAGTATTGATAA

hide sequence

RefSeq Acc Id:

XM_006238978 ⟹ XP_006239040

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	147,797,888 - 147,807,924 (-)	NCBI
mRatBN7.2	5	142,513,714 - 142,523,730 (-)	NCBI
Rnor_6.0	5	148,382,706 - 148,392,724 (-)	NCBI
Rnor_5.0	5	152,101,199 - 152,111,202 (-)	NCBI

Sequence:

show sequence

CCCTGCGCTCCTCACTTGACTCGGTCTGGCAGTCTCGAGCTTGGAGGCGGAGGCGCGCAGGGCA
GCCTGGGTCCAGCCCACACCCCTCACCAGGCACCATGTGGGGATGTCCGCTAGGGCTGCTATTG
CTGCTGCTGGCTGGCCAGGCTGCCCTGGAGGCCCGGCGGAGTCGTTGGCGCAGGGAGCTGGCGC
CAGGGCTGCACCTGCGGGGCATCCGGGACGCCGGTGGCAGATACTGCCAAGAGCAGGACATGTG
CTGCCGCGGCCGTGCTGACGAGTGTGCTTTGCCCTACCTGGGAGCCACCTGTTACTGTGACCTC
TTCTGCAACCGCACCGTCTCTGACTGCTGCCCTGACTTTTGGGACTTCTGCCTCGGGATTCCAC
CCCCCTTCCCTCCTGTCCAAGGTTGCATGCATGCGGGCCGGATCTACCCAATCTTCGGAACCTA
TTGGGAAAACTGCAATCGGTGCACCTGCCATGAGAAAGGGCAGTGGGAATGTGACCAGGAGCCA
TGTCTAGTGGACCCAGCCATGATTAAAGCCATCAACCGGGGCAACTACGGGTGGCAGGCTGGGA
ACCACAGTGCCTTCTGGGGCATGACCCTGGATGAGGGCATTCGATACCGGCTGGGCACAATCCG
CCCATCTTCCTCTGTCATGAATATGAATGAGATTTATACGGTGCTGGGACAAGGAGAAGTGCTA
CCCACTGCCTTTGAGGCTTCCGAGAAGTGGCCCAACCTGATCCATGAGCCGCTGGACCAGGGCA
ACTGTGCGGGTTCCTGGGCCTTCTCCACAGCAGCTGTCGCATCTGACCGAGTGTCCATCCATTC
TTTGGGACACATGACACCCATCCTCTCACCGCAGAACCTGCTATCCTGTGATACCCACCACCAG
AAGGGCTGCCGAGGTGGGCGTCTCGATGGTGCTTGGTGGTTCCTGCGGTGCCGAGGGGTGGTGT
CTGATAACTGTTACCCATTCTCCGGCCGTGAGCAGAACGACGAGGCCAGCCCCACTCCTCGATG
CATGATGCACAGCCGCGCCATGGGGCGGGGCAAGCGCCAGGCCACTTCTCGCTGCCCCAATAGT
CATGTTGATTCCAATGACATCTACCAGGTCACGCCTGTCTACCGCCTGGCCTCCGATGAGAAGG
AGATCATGAAGGAGCTAATGGAAAATGGCCCTGTTCAAGCGCTTATGGAAGTACACGAAGACTT
CTTCTTGTACCAGCGAGGCATCTACAGCCACACACCTGTAAGCCAGGGGAGGCCAGAGCAGTAC
CGCCGACACGGGACTCACTCTGTCAAGATCACAGGGTGGGGAGAAGAGACACTGCCAGACGGAA
GGACGATCAAGTACTGGACTGCTGCCAACTCGTGGGGCCCATGGTGGGGTGAGAGGGGCCACTT
CCGAATCGTGCGTGGCACCAACGAGTGTGACATCGAGACCTTCGTGCTGGGCGTCTGGGGCCGA
GTAGGAATGGAGGACATGGGGCACCACTGAGTCTCGGCCACTAAGCTAGGTGGGATCCACAGCC
ACAGAAGAGGCCTTGGGGGCCACGCCGATGAGGCCTTGGGACCAGGTGCTAATCCCCTCAGACT
CAGATCCACACAAACGCAGAACCCCACCTGGGAGCTAATGTCCCTCAGGGAGCAACAGTGAGGC
TGGAGGGAACCCTCAGACATCACAGCCGGAACTGGAAAGGGCCCGGCTTGGAAACTGCAGGGAG
TAAAATTCCCAGGCCCCTGGTCAGCCAGCCCAAGACCATGGGAGCTAAGACACCCCAACCTCTT
CATCCTCCTACCCAACCTCATTCTTATTTTTTCATTCTCCTTGGTGGATTCTGCCCATCCCCCT
GGCCTCCGTTCTGGCTGGACCTTTCCATCCTCAACACTGCTTTCTTACTCTTTAAAAATATTTA
TTTTTCTTTTCATTAAAATAAAACCAAAGTATTGATAA

hide sequence

RefSeq Acc Id:

XM_039110893 ⟹ XP_038966821

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	147,797,888 - 147,807,751 (-)	NCBI
mRatBN7.2	5	142,513,717 - 142,523,578 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001420681	(Get FASTA)	NCBI Sequence Viewer
	NP_446034	(Get FASTA)	NCBI Sequence Viewer
	XP_006239039	(Get FASTA)	NCBI Sequence Viewer
	XP_006239040	(Get FASTA)	NCBI Sequence Viewer
	XP_038966821	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97299	(Get FASTA)	NCBI Sequence Viewer
	BAB18637	(Get FASTA)	NCBI Sequence Viewer
	EDL80584	(Get FASTA)	NCBI Sequence Viewer
	EDL80585	(Get FASTA)	NCBI Sequence Viewer
	EDL80586	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018464
GenBank Protein	Q9EQT5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_446034 ⟸ NM_053582
- Peptide Label:	precursor
- UniProtKB:	Q9EQT5 (UniProtKB/Swiss-Prot), A6ISN5 (UniProtKB/TrEMBL), F7F528 (UniProtKB/TrEMBL), Q4V8N0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MWGCPLGLLLLLLAGQAALEARRSRWRRELAPGLHLRGIRDAGGRYCQEQDMCCRGRADECALP YLGATCYCDLFCNRTVSDCCPDFWDFCLGIPPPFPPVQGCMHAGRIYPIFGTYWENCNRCTCHE KGQWECDQEPCLVDPAMIKAINRGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMNEI YTVLGQGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQ NLLSCDTHHQKGCRGGRLDGAWWFLRRRGVVSDNCYPFSGREQNDEASPTPRCMMHSRAMGRGK RQATSRCPNSQVDSNDIYQVTPVYRLASDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHT PVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGINECDI ETFVLGVWGRVGMEDMGHH hide sequence

RefSeq Acc Id:

XP_006239040 ⟸ XM_006238978

- Peptide Label:

isoform X1

- Sequence:

show sequence

MWGCPLGLLLLLLAGQAALEARRSRWRRELAPGLHLRGIRDAGGRYCQEQDMCCRGRADECALP
YLGATCYCDLFCNRTVSDCCPDFWDFCLGIPPPFPPVQGCMHAGRIYPIFGTYWENCNRCTCHE
KGQWECDQEPCLVDPAMIKAINRGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMNEI
YTVLGQGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQ
NLLSCDTHHQKGCRGGRLDGAWWFLRCRGVVSDNCYPFSGREQNDEASPTPRCMMHSRAMGRGK
RQATSRCPNSHVDSNDIYQVTPVYRLASDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHT
PVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDI
ETFVLGVWGRVGMEDMGHH

hide sequence

RefSeq Acc Id:

XP_006239039 ⟸ XM_006238977

- Peptide Label:

isoform X1

- Sequence:

show sequence

MWGCPLGLLLLLLAGQAALEARRSRWRRELAPGLHLRGIRDAGGRYCQEQDMCCRGRADECALP
YLGATCYCDLFCNRTVSDCCPDFWDFCLGIPPPFPPVQGCMHAGRIYPIFGTYWENCNRCTCHE
KGQWECDQEPCLVDPAMIKAINRGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMNEI
YTVLGQGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQ
NLLSCDTHHQKGCRGGRLDGAWWFLRCRGVVSDNCYPFSGREQNDEASPTPRCMMHSRAMGRGK
RQATSRCPNSHVDSNDIYQVTPVYRLASDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHT
PVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDI
ETFVLGVWGRVGMEDMGHH

hide sequence

Ensembl Acc Id:

ENSRNOP00000018464 ⟸ ENSRNOT00000018464

Ensembl Acc Id:

ENSRNOP00000071970 ⟸ ENSRNOT00000080166

RefSeq Acc Id:	XP_038966821 ⟸ XM_039110893
- Peptide Label:	isoform X1
- UniProtKB:	Q9EQT5 (UniProtKB/Swiss-Prot), A6ISN5 (UniProtKB/TrEMBL), F7F528 (UniProtKB/TrEMBL), Q4V8N0 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000094381 ⟸ ENSRNOT00000093760

Protein Domains

SMB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9EQT5-F1-model_v2	AlphaFold	Q9EQT5	1-467	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694081

Promoter ID:

EPDNEW_R4605

Type:

multiple initiation site

Name:

Tinagl1_1

Description:

tubulointerstitial nephritis antigen-like 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	148,392,711 - 148,392,771	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:70956	AgrOrtholog
BioCyc Gene	G2FUF-39762	BioCyc
Ensembl Genes	ENSRNOG00000013179	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000018464	ENTREZGENE
Gene3D-CATH	Cysteine proteinases	UniProtKB/Swiss-Prot
InterPro	Papain-like_cys_pep_sf	UniProtKB/Swiss-Prot
	Pept_his_AS	UniProtKB/Swiss-Prot
	Peptidase_C1A	UniProtKB/Swiss-Prot
	Peptidase_C1A_C	UniProtKB/Swiss-Prot
	Somatomedin_B_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:94174	UniProtKB/Swiss-Prot
NCBI Gene	Tinagl1	ENTREZGENE
PANTHER	CYSTEINE PROTEASE FAMILY C1-RELATED	UniProtKB/Swiss-Prot
Pfam	Peptidase_C1	UniProtKB/Swiss-Prot
PhenoGen	Tinagl1	PhenoGen
PROSITE	SMB_1	UniProtKB/Swiss-Prot
	SMB_2	UniProtKB/Swiss-Prot
	THIOL_PROTEASE_HIS	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000013179	RatGTEx
SMART	Pept_C1	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF54001	UniProtKB/Swiss-Prot
UniProt	A0A0G2K1S8_RAT	UniProtKB/TrEMBL
	A0A8I6AM28_RAT	UniProtKB/TrEMBL
	A6ISN5	ENTREZGENE, UniProtKB/TrEMBL
	F7F528	ENTREZGENE, UniProtKB/TrEMBL
	Q4V8N0	ENTREZGENE
	Q9EQT5	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-18	Tinagl1	tubulointerstitial nephritis antigen-like 1	Lcn7	lipocalin 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2003-04-09	Lcn7	lipocalin 7			Symbol and Name updated	629477	APPROVED
2003-03-12	Lcn7	lipocalin 7	gis5	glucocorticoid-inducible protein	Data merged from RGD:620316	628472	PROVISIONAL
2002-08-07	gis5	glucocorticoid-inducible protein			Symbol and Name status set to provisional	70820	PROVISIONAL
2002-07-09	Lcn7	lipocalin 7			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_domains	the human homolog, like the mouse protein, has a serine replacing the cysteine residue in the active site of the cathepsin B-like domain, rendering it proteolytically inactive	1358119
gene_expression	mouse homolog is expressed in lung endothelial cells and may be associated with vascular development and angiogenesis	1358116

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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