Ykt6 (YKT6 vesicular SNARE protein) - Rat Genome Database

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Gene: Ykt6 (YKT6 vesicular SNARE protein) Rattus norvegicus
Analyze
Symbol: Ykt6
Name: YKT6 vesicular SNARE protein (Ensembl:YKT6 v-SNARE homolog)
RGD ID: 70897
Description: Predicted to enable SNAP receptor activity and protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi; and vesicle docking involved in exocytosis. Located in apical dendrite; basal dendrite; and neuronal cell body. Part of SNARE complex. Orthologous to human YKT6 (YKT6 v-SNARE homolog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: prenylated SNARE protein; synaptobrevin homolog YKT6; YKT6 homolog; YKT6 homolog (S. Cerevisiae); YKT6 v-SNARE homolog; YKT6 v-SNARE homolog (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,041,393 - 85,057,347 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1485,046,164 - 85,057,346 (+)EnsemblGRCr8
mRatBN7.21480,832,187 - 80,843,394 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,832,187 - 80,843,385 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,234,395 - 85,243,714 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,474,492 - 86,483,811 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,923,806 - 82,933,125 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,196,018 - 86,207,057 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,195,892 - 86,205,712 (+)Ensemblrn6Rnor6.0
Rnor_5.01486,880,204 - 86,889,524 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41486,619,828 - 86,629,148 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1479,716,098 - 79,725,418 (+)NCBICelera
RGSC_v3.11486,638,972 - 86,648,293 (+)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
enniatin  (ISO)
ethanol  (EXP)
fenthion  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
furan  (EXP)
genistein  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
ivermectin  (ISO)
menadione  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
tamibarotene  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Characterization of the sequence and expression of a Ykt6 prenylated SNARE from rat. Catchpoole DR and Wanjin H, DNA Cell Biol 1999 Feb;18(2):141-5.
2. Omega-3 and omega-6 fatty acids stimulate cell membrane expansion by acting on syntaxin 3. Darios F and Davletov B, Nature. 2006 Apr 6;440(7085):813-7.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Intramolecular protein-protein and protein-lipid interactions control the conformation and subcellular targeting of neuronal Ykt6. Hasegawa H, etal., J Cell Sci. 2004 Sep 1;117(Pt 19):4495-508.
5. Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain. Hasegawa H, etal., Mol Biol Cell. 2003 Feb;14(2):698-720.
6. Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi transport. McNew JA, etal., J Biol Chem. 1997 Jul 11;272(28):17776-83.
7. Gene Data Set MGD Curation, June 12, 2002
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. R-SNARE ykt6 resides in membrane-associated protease-resistant protein particles and modulates cell cycle progression when over-expressed. Thayanidhi N, etal., Biol Cell. 2012 Jul;104(7):397-417. doi: 10.1111/boc.201100048. Epub 2012 May 29.
Additional References at PubMed
PMID:11323436   PMID:11927603   PMID:12388752   PMID:15215310   PMID:15479160   PMID:17618625   PMID:20159557   PMID:23376485   PMID:25468996   PMID:27493064   PMID:30119892   PMID:37380075  


Genomics

Comparative Map Data
Ykt6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,041,393 - 85,057,347 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1485,046,164 - 85,057,346 (+)EnsemblGRCr8
mRatBN7.21480,832,187 - 80,843,394 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,832,187 - 80,843,385 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,234,395 - 85,243,714 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,474,492 - 86,483,811 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,923,806 - 82,933,125 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,196,018 - 86,207,057 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,195,892 - 86,205,712 (+)Ensemblrn6Rnor6.0
Rnor_5.01486,880,204 - 86,889,524 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41486,619,828 - 86,629,148 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1479,716,098 - 79,725,418 (+)NCBICelera
RGSC_v3.11486,638,972 - 86,648,293 (+)NCBI
Cytogenetic Map14q21NCBI
YKT6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,200,978 - 44,214,294 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,200,959 - 44,214,294 (+)Ensemblhg38GRCh38
GRCh37744,240,577 - 44,253,893 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,207,103 - 44,220,418 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34744,013,817 - 44,027,132NCBI
Celera744,338,544 - 44,351,859 (+)NCBICelera
Cytogenetic Map7p13NCBI
HuRef744,125,857 - 44,139,172 (+)NCBIHuRef
CHM1_1744,244,442 - 44,257,752 (+)NCBICHM1_1
T2T-CHM13v2.0744,359,565 - 44,372,881 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,280,084 - 44,293,399 (+)NCBI
Ykt6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,905,779 - 5,917,780 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,905,693 - 5,917,780 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38115,955,758 - 5,967,780 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,955,693 - 5,967,780 (+)Ensemblmm10GRCm38
MGSCv37115,855,761 - 5,867,783 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36115,855,835 - 5,867,783 (+)NCBIMGSCv36mm8
Celera116,447,816 - 6,459,840 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.89NCBI
Ykt6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,763,982 - 7,776,153 (-)Ensembl
ChiLan1.0NW_0049554567,764,125 - 7,776,429 (-)NCBIChiLan1.0ChiLan1.0
YKT6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,111,738 - 49,125,662 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,436,478 - 97,450,400 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,915,181 - 44,928,001 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,975,782 - 44,996,195 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,982,748 - 44,994,183 (+)EnsemblpanPan2panpan1.1
YKT6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,131,031 - 2,140,443 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01614,721,412 - 14,730,822 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,721,419 - 14,730,907 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,352,875 - 14,362,275 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,333,138 - 14,342,549 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ykt6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,954,485 - 99,967,329 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,166,153 - 19,179,719 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,166,225 - 19,179,060 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YKT6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,960,113 - 50,971,384 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11850,961,451 - 50,971,384 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,855,334 - 55,865,266 (-)NCBISscrofa10.2Sscrofa10.2susScr3
YKT6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,454,126 - 14,467,452 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,452,968 - 14,467,417 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660628,048,115 - 8,061,488 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ykt6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,832,114 - 7,845,149 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247407,832,436 - 7,844,416 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ykt6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11174,904,550 - 74,915,938 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ykt6
69 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:36
Count of miRNA genes:34
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000020693
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat

Markers in Region
D14Mit16  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81485,042,083 - 85,042,220 (+)Marker Load Pipeline
mRatBN7.21480,828,129 - 80,828,266 (+)MAPPERmRatBN7.2
Rnor_6.01486,191,794 - 86,191,930NCBIRnor6.0
Rnor_5.01486,875,980 - 86,876,116UniSTSRnor5.0
RGSC_v3.41486,615,603 - 86,615,740RGDRGSC3.4
RGSC_v3.41486,615,604 - 86,615,740UniSTSRGSC3.4
Celera1479,711,874 - 79,712,010UniSTS
RGSC_v3.11486,634,748 - 86,634,885RGD
RH 3.4 Map14572.7RGD
RH 3.4 Map14572.7UniSTS
RH 2.0 Map14705.3RGD
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020693   ⟹   ENSRNOP00000020693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1485,046,164 - 85,057,340 (+)Ensembl
mRatBN7.2 Ensembl1480,832,187 - 80,843,385 (+)Ensembl
Rnor_6.0 Ensembl1486,195,892 - 86,205,712 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115586   ⟹   ENSRNOP00000079175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1485,046,168 - 85,057,346 (+)Ensembl
mRatBN7.2 Ensembl1480,832,187 - 80,843,385 (+)Ensembl
RefSeq Acc Id: NM_031692   ⟹   NP_113880
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,046,189 - 85,057,347 (+)NCBI
mRatBN7.21480,832,235 - 80,843,394 (+)NCBI
Rnor_6.01486,196,018 - 86,205,338 (+)NCBI
Rnor_5.01486,880,204 - 86,889,524 (+)NCBI
RGSC_v3.41486,619,828 - 86,629,148 (+)RGD
Celera1479,716,098 - 79,725,418 (+)RGD
Sequence:
RefSeq Acc Id: XM_039092394   ⟹   XP_038948322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,046,152 - 85,057,347 (+)NCBI
mRatBN7.21480,832,204 - 80,843,394 (+)NCBI
RefSeq Acc Id: XM_063273576   ⟹   XP_063129646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,041,393 - 85,057,347 (+)NCBI
RefSeq Acc Id: XM_063273577   ⟹   XP_063129647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,046,141 - 85,057,347 (+)NCBI
RefSeq Acc Id: NP_113880   ⟸   NM_031692
- UniProtKB: Q5EGY4 (UniProtKB/Swiss-Prot),   O35487 (UniProtKB/Swiss-Prot),   A0A8I6G2X5 (UniProtKB/TrEMBL),   A6IKR3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020693   ⟸   ENSRNOT00000020693
RefSeq Acc Id: XP_038948322   ⟸   XM_039092394
- Peptide Label: isoform X3
- UniProtKB: A6IKR4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079175   ⟸   ENSRNOT00000115586
RefSeq Acc Id: XP_063129646   ⟸   XM_063273576
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063129647   ⟸   XM_063273577
- Peptide Label: isoform X2
Protein Domains
Longin   v-SNARE coiled-coil homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5EGY4-F1-model_v2 AlphaFold Q5EGY4 1-198 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699468
Promoter ID:EPDNEW_R9991
Type:initiation region
Name:Ykt6_1
Description:YKT6 v-SNARE homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,195,929 - 86,195,989EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70897 AgrOrtholog
BioCyc Gene G2FUF-15107 BioCyc
Ensembl Genes ENSRNOG00000014785 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020693 ENTREZGENE
  ENSRNOT00000020693.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot
  Longin domain UniProtKB/Swiss-Prot
InterPro Longin-like_dom_sf UniProtKB/Swiss-Prot
  Longin_dom UniProtKB/Swiss-Prot
  R-SNARE_YKT6 UniProtKB/Swiss-Prot
  V_SNARE_CC UniProtKB/Swiss-Prot
KEGG Report rno:64351 UniProtKB/Swiss-Prot
NCBI Gene Ykt6 ENTREZGENE
PANTHER SYNAPTOBREVIN HOMOLOG YKT6 UniProtKB/Swiss-Prot
  SYNAPTOBREVIN HOMOLOG YKT6 UniProtKB/Swiss-Prot
Pfam Longin UniProtKB/Swiss-Prot
  Synaptobrevin UniProtKB/Swiss-Prot
PhenoGen Ykt6 PhenoGen
PROSITE LONGIN UniProtKB/Swiss-Prot
  V_SNARE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014785 RatGTEx
SMART Longin UniProtKB/Swiss-Prot
Superfamily-SCOP SNARE fusion complex UniProtKB/Swiss-Prot
  SSF64356 UniProtKB/Swiss-Prot
UniProt A0A8I6G2X5 ENTREZGENE, UniProtKB/TrEMBL
  A6IKR3 ENTREZGENE, UniProtKB/TrEMBL
  A6IKR4 ENTREZGENE, UniProtKB/TrEMBL
  O35487 ENTREZGENE
  Q5EGY4 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O35487 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Ykt6  YKT6 vesicular SNARE protein  Ykt6  YKT6 v-SNARE homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-03-21 Ykt6  YKT6 v-SNARE homolog  Ykt6  YKT6 v-SNARE homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Ykt6  YKT6 v-SNARE homolog (S. cerevisiae)  Ykt6  YKT6 homolog (S. Cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Ykt6  YKT6 homolog (S. Cerevisiae)  Ykt6  prenylated SNARE protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Ykt6  prenylated SNARE protein      Symbol and Name updated 629477 APPROVED
2003-03-10 Ykt6  prenylated SNARE protein  Ykt6-pending  prenylated SNARE protein  Data merged from RGD:620008 628472 PROVISIONAL
2002-08-07 Ykt6-pending  prenylated SNARE protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-07-09 Ykt6  prenylated SNARE protein      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization may be a soluble form of prenylated N-ethylmaleimide-sensitive fusion protein receptor 70609