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Gene: Kcnip1 (potassium voltage-gated channel interacting protein 1) Rattus norvegicus

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Symbol:

Kcnip1

Name:

potassium voltage-gated channel interacting protein 1

RGD ID:

70886

Description:

Enables calcium ion binding activity; potassium channel regulator activity; and transmembrane transporter binding activity. Involved in positive regulation of action potential. Located in dendrite and neuronal cell body. Part of potassium channel complex. Orthologous to human KCNIP1 (potassium voltage-gated channel interacting protein 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

A-type potassium channel modulatory protein 1; A-type potassium channel modulatory protein KCNIP1; Kchip1; Kv channel-interacting protein 1; potassium channel interacting protein 1; potassium channel-interacting protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	18,723,726 - 19,093,025 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	18,723,726 - 19,093,087 (-)	Ensembl				GRCr8
mRatBN7.2	10	18,219,519 - 18,588,833 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	18,219,519 - 18,589,045 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	22,974,802 - 23,344,367 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	22,463,387 - 22,832,928 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	17,944,312 - 18,311,678 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	18,558,128 - 18,942,677 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	18,558,128 - 18,942,540 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	18,443,846 - 18,821,334 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	18,549,984 - 18,565,789 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	17,854,471 - 18,221,759 (-)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Idiopathic Generalized Epilepsy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,3-dinitrobenzene (EXP)

17alpha-ethynylestradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4,4'-diaminodiphenylmethane (ISO)

4-aminopyridine (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) chloride (ISO)

decabromodiphenyl ether (EXP)

ethylparaben (ISO)

fenvalerate (EXP)

formaldehyde (ISO)

furan (EXP)

gamma-aminobutyric acid (EXP)

glyphosate (ISO)

lanthanum trichloride (EXP)

methapyrilene (ISO)

methoxychlor (EXP)

N-methyl-4-phenylpyridinium (ISO)

ochratoxin A (ISO)

paracetamol (ISO)

potassium dichromate (ISO)

rotenone (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

titanium dioxide (ISO)

triclosan (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

monoatomic ion transmembrane transport (IEA)

monoatomic ion transport (IEA)

positive regulation of action potential (IDA)

potassium ion transmembrane transport (IEA)

potassium ion transport (IEA)

regulation of potassium ion transmembrane transport (IBA,IEA,ISO,ISS)

regulation of signal transduction (IBA)

Cellular Component

cytoplasm (IEA,ISO,ISS)

cytoplasmic side of plasma membrane (IEA,ISO,ISS)

dendrite (IDA,IEA)

Kv4.3-KChIP1 channel complex (IEA,ISO)

monoatomic ion channel complex (IEA)

neuronal cell body (IDA)

plasma membrane (IEA)

potassium channel complex (IDA)

protein-containing complex (IEA)

voltage-gated potassium channel complex (IBA,IEA,ISO,ISS)

Molecular Function

calcium ion binding (IBA,IDA,IEA,ISO)

metal ion binding (IEA)

potassium channel activity (IEA)

potassium channel regulator activity (IBA,IDA,IEA,ISO)

protein binding (IPI,ISO)

protein-containing complex binding (IDA)

transmembrane transporter binding (IBA,IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium/calcium-mediated signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional properties of a brain-specific NH2-terminally spliced modulator of Kv4 channels.	Boland LM, etal., Am J Physiol Cell Physiol 2003 Jul;285(1):C161-70.
2.	Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.	Dabrowska J and Rainnie DG, Neuroscience. 2010 Dec 15;171(3):721-33. doi: 10.1016/j.neuroscience.2010.09.011. Epub 2010 Sep 16.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	The diversity of calcium sensor proteins in the regulation of neuronal function.	McCue HV, etal., Cold Spring Harb Perspect Biol. 2010 Aug;2(8):a004085. doi: 10.1101/cshperspect.a004085. Epub 2010 Jul 28.
6.	Gene Data Set	MGD Curation, June 12, 2002
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	Molecular cloning and expression of the novel splice variants of K(+) channel-interacting protein 2.	Ohya S, etal., Biochem Biophys Res Commun 2001 Mar 23;282(1):96-102.
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1.	Scannevin RH, etal., Neuron. 2004 Feb 19;41(4):587-98. doi: 10.1016/s0896-6273(04)00049-2.
13.	A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channels.	Shibata R, etal., J Biol Chem 2003 Sep 19;278(38):36445-54. Epub 2003 Jun 26.
14.	Light and electron microscopic analysis of KChIP and Kv4 localization in rat cerebellar granule cells.	Strassle BW, etal., J Comp Neurol. 2005 Apr 4;484(2):144-55.
15.	Structural insights into the functional interaction of KChIP1 with Shal-type K(+) channels.	Zhou W, etal., Neuron. 2004 Feb 19;41(4):573-86.

Additional References at PubMed

PMID:10676964	PMID:11423117	PMID:12138168	PMID:15356203	PMID:17187064	PMID:17725712	PMID:19261906	PMID:19713751	PMID:19896980	PMID:24037673	PMID:25917026

Genomics

Comparative Map Data

Kcnip1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	18,723,726 - 19,093,025 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	18,723,726 - 19,093,087 (-)	Ensembl				GRCr8
mRatBN7.2	10	18,219,519 - 18,588,833 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	18,219,519 - 18,589,045 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	22,974,802 - 23,344,367 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	22,463,387 - 22,832,928 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	17,944,312 - 18,311,678 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	18,558,128 - 18,942,677 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	18,558,128 - 18,942,540 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	18,443,846 - 18,821,334 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	18,549,984 - 18,565,789 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	17,854,471 - 18,221,759 (-)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

KCNIP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	170,353,487 - 170,736,632 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	170,353,487 - 170,736,632 (+)	Ensembl			hg38	GRCh38
GRCh37	5	169,780,491 - 170,163,636 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	169,713,459 - 170,096,214 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	169,863,625 - 170,096,212	NCBI
Celera	5	165,812,814 - 166,196,213 (+)	NCBI		Celera
Cytogenetic Map	5	q35.1	NCBI
HuRef	5	164,879,389 - 165,261,398 (+)	NCBI		HuRef
CHM1_1	5	169,213,393 - 169,596,144 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	170,892,193 - 171,275,276 (+)	NCBI		T2T-CHM13v2.0

Kcnip1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	33,579,339 - 33,943,854 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	33,579,339 - 33,943,152 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	33,629,339 - 33,993,348 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	33,629,339 - 33,993,152 (-)	Ensembl			mm10	GRCm38
MGSCv37	11	33,529,780 - 33,743,527 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	33,529,780 - 33,743,527 (-)	NCBI		MGSCv36	mm8
Celera	11	36,039,564 - 36,254,398 (-)	NCBI		Celera
Cytogenetic Map	11	A4	NCBI
cM Map	11	19.21	NCBI

Kcnip1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	23,437,358 - 23,662,533 (+)	Ensembl
ChiLan1.0	NW_004955408	23,299,192 - 23,662,395 (+)	NCBI	ChiLan1.0	ChiLan1.0

KCNIP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	165,508,638 - 165,892,400 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	163,648,181 - 164,031,942 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	165,711,110 - 166,095,049 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	172,470,524 - 172,853,992 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	172,622,331 - 172,853,992 (+)	Ensembl			panPan2	panpan1.1

KCNIP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	41,220,128 - 41,566,841 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	41,223,369 - 41,431,510 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	41,172,875 - 41,519,111 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	41,602,547 - 41,942,922 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	41,602,549 - 41,942,584 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	41,416,697 - 41,625,830 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	41,607,074 - 41,947,032 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	42,117,879 - 42,457,557 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Kcnip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	95,445,808 - 95,758,308 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936609	4,168,480 - 4,361,586 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936609	4,168,487 - 4,481,161 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KCNIP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	53,267,523 - 53,653,730 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	16	53,272,652 - 53,694,974 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	57,545,284 - 57,558,635 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KCNIP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	72,555,329 - 72,934,425 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	72,910,263 - 72,934,422 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666034	5,723,126 - 5,957,161 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kcnip1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	19,255,587 - 19,464,938 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624733	19,255,938 - 19,625,087 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Kcnip1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	6,439,637 - 6,808,026 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Kcnip1
2874 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	174
Count of miRNA genes:	69
Interacting mature miRNAs:	71
Transcripts:	ENSRNOT00000007187, ENSRNOT00000040737
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15776754	60776754	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
2293680	Bss40	Bone structure and strength QTL 40	5.66	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	10	1	35730538	Rat
7387235	Uae41	Urinary albumin excretion QTL 41	5.26	0.1874	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	10	1	30004247	Rat
737823	Alc12	Alcohol consumption QTL 12	4.5		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	10	17749784	20796344	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	18035782	63035782	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
737820	Alc9	Alcohol consumption QTL 9	2.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	10	15762230	19737486	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
2298495	Eae23	Experimental allergic encephalomyelitis QTL 23	16.93		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	10	16175525	61175525	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18668419	63668419	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
631660	Hcar1	Hepatocarcinoma resistance QTL 1	3.4	0.0001	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	10	6661118	35509383	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	18035782	63035782	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat

Markers in Region

AU046920

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	18,284,013 - 18,284,176 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	18,629,143 - 18,629,305	NCBI	Rnor6.0
Rnor_5.0	10	18,514,094 - 18,514,256	UniSTS	Rnor5.0
RGSC_v3.4	10	18,623,429 - 18,623,591	UniSTS	RGSC3.4
Celera	10	17,918,049 - 17,918,211	UniSTS
Cytogenetic Map	10	q12	UniSTS

RH142383

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	18,565,193 - 18,565,369 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	18,919,035 - 18,919,210	NCBI	Rnor6.0
Rnor_5.0	10	18,797,692 - 18,797,867	UniSTS	Rnor5.0
RGSC_v3.4	10	18,911,999 - 18,912,174	UniSTS	RGSC3.4
Celera	10	18,196,301 - 18,196,476	UniSTS
Cytogenetic Map	10	q12	UniSTS

BF405894

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	18,397,901 - 18,397,992 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	18,746,739 - 18,746,829	NCBI	Rnor6.0
Rnor_5.0	10	18,625,945 - 18,626,035	UniSTS	Rnor5.0
RGSC_v3.4	10	18,743,401 - 18,743,491	UniSTS	RGSC3.4
Celera	10	18,030,228 - 18,030,318	UniSTS
Cytogenetic Map	10	q12	UniSTS

AA849706

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	18,219,699 - 18,219,894 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	18,558,309 - 18,558,503	NCBI	Rnor6.0
Rnor_5.0	10	18,444,027 - 18,444,221	UniSTS	Rnor5.0
RGSC_v3.4	10	18,549,360 - 18,549,554	UniSTS	RGSC3.4
Celera	10	17,854,652 - 17,854,846	UniSTS
Cytogenetic Map	10	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	11	31	144	57	56	25	25	25	6	201	85	10	118	68	91	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001261387	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001261388	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001261389	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_022929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246105	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB046443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY082657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY082658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY142709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000007187 ⟹ ENSRNOP00000007187

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	18,723,726 - 18,940,809 (-)	Ensembl
mRatBN7.2 Ensembl	10	18,219,519 - 18,436,359 (-)	Ensembl
Rnor_6.0 Ensembl	10	18,558,936 - 18,942,540 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000040737 ⟹ ENSRNOP00000046697

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	18,723,726 - 19,092,888 (-)	Ensembl
mRatBN7.2 Ensembl	10	18,219,519 - 18,588,696 (-)	Ensembl
Rnor_6.0 Ensembl	10	18,558,128 - 18,579,632 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079031 ⟹ ENSRNOP00000071584

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	18,723,726 - 18,774,994 (-)	Ensembl
mRatBN7.2 Ensembl	10	18,219,519 - 18,270,788 (-)	Ensembl
Rnor_6.0 Ensembl	10	18,558,128 - 18,574,710 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083090 ⟹ ENSRNOP00000074006

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	18,723,726 - 18,940,809 (-)	Ensembl
mRatBN7.2 Ensembl	10	18,219,519 - 18,436,359 (-)	Ensembl
Rnor_6.0 Ensembl	10	18,558,129 - 18,574,909 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000120110 ⟹ ENSRNOP00000094374

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	18,723,726 - 19,093,087 (-)	Ensembl
mRatBN7.2 Ensembl	10	18,219,519 - 18,589,045 (-)	Ensembl

RefSeq Acc Id:

NM_001261387 ⟹ NP_001248316

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	18,723,726 - 19,093,025 (-)	NCBI
mRatBN7.2	10	18,219,519 - 18,588,833 (-)	NCBI
Rnor_6.0	10	18,558,128 - 18,942,677 (-)	NCBI
Rnor_5.0	10	18,443,846 - 18,821,334 (-)	NCBI
Celera	10	17,854,471 - 18,221,759 (-)	NCBI

Sequence:

show sequence

GCTGTGCCGGAGACTGGTTTCTGGGGTGCATCAATCTTTCAGGGTTCACCTAAGCAGGCTCCAA
GGTCCAGAGGCACGCAAGGTGCGTACTAACCCTTCTGGGCGCTGACTGCAGAACCTGCCTCCCC
TCTGCCACTATGAGCGGCTGCTCCAAAAGATGCAGACTCGGGTTCGTGAAATTTGCCCAGACCA
TCTTTAAACTCATCACCGGGACCCTCAGCAAAGACATCGCCTGGTGGTATTACCAGTATCAGAG
AGACAAGATCGAGGATGATCTGGAGATGACCATGGTTTGCCATCGGCCTGAGGGACTGGAGCAG
CTTGAGGCACAGACGAACTTCACCAAGAGAGAACTGCAAGTCCTTTACCGGGGATTCAAAAACG
AGTGCCCCAGTGGTGTGGTTAACGAAGAGACATTCAAGCAGATCTACGCTCAGTTTTTCCCTCA
TGGAGATGCCAGCACATACGCACATTACCTCTTCAATGCCTTCGACACCACCCAGACAGGCTCT
GTAAAGTTCGAGGACTTTGTGACTGCTCTGTCGATTTTACTGAGAGGAACGGTCCATGAAAAAC
TGAGGTGGACGTTTAATTTGTACGACATCAATAAAGACGGCTACATAAACAAAGAGGAGATGAT
GGACATAGTGAAAGCCATCTATGACATGATGGGGAAATACACCTATCCTGTGCTCAAAGAGGAC
ACTCCCAGGCAGCACGTGGACGTCTTCTTCCAGAAAATGGATAAAAATAAAGATGGCATTGTAA
CGTTAGACGAATTTCTCGAGTCCTGTCAGGAGGATGACAACATCATGAGGTCTCTACAGCTGTT
CCAAAATGTCATGTAACTGAGGACACTGGCCATCCTGCTCTCAGAGACACTGAAAAACACCTCA
ATGCCCTGATCTGCCCTTGTTCCAGTTTTACACATCAACTCTCGGGACAGAAATACCTTTTACA
CTTTGGAAGAATTCTCTGCTGAAGACTTTCTACAAAACCTGGCACCGCGTGGCTCAGTCTCTGA
TTGCCAACTCTTCCTCCCTCCTCCTCTTGAGAGGGACGAGCTGAAATCCGAAGTTTGTTTTGGA
AGCATGCCCATCTCTCCATGCTGCTGCTGCCCTGTGGAAGGCCCCTCTGCTTGAGCTTAAACAG
TAGTGCACAGTTTTCTGCGTATACAGATCCCCAACTCACTGCCTCTAAGTCAGGCAGACCCTGA
TCAATCTGAACCAAATGTGCACCATCCTCCGATGGCCTCCCAAGCCAATGTGCCTGCTTCTCTT
CCTCTGGTGGGAAGAAAGAACGCTCTACAGAGCACTTAGAGCTTACCATGAAAATACTGGGAGA
GGCAGCAACTAACATATGTAGAATAGGACTGAATTATTAAGCATGGTGGTATCAGATGATGCAA
ACAGCCCATGTCATTTTTTTTCCAGAGGTAGGGACTAATAATTCTCCCACACTAGCACCTACGA
TCATAGAACAAGTCTTTTAACACATCCAGGAGGGAAACCGCTGCCCAGTGGTCTATCCCTTCTC
TCCATCCCCTGCTCAAGCCCAGCACTGCATGTCTCTCCCGGAAGGTCCAGAATGCCTGTGAAAT
GCTGTAACTTTTATACCCTGTTATAATCAATAAACAGAACTATTTCGTACACA

hide sequence

RefSeq Acc Id:

NM_001261388 ⟹ NP_001248317

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	18,723,726 - 19,093,025 (-)	NCBI
mRatBN7.2	10	18,219,519 - 18,588,833 (-)	NCBI
Rnor_6.0	10	18,558,128 - 18,942,677 (-)	NCBI
Rnor_5.0	10	18,443,846 - 18,821,334 (-)	NCBI
Celera	10	17,854,471 - 18,221,759 (-)	NCBI

Sequence:

show sequence

GCTGTGCCGGAGACTGGTTTCTGGGGTGCATCAATCTTTCAGGGTTCACCTAAGCAGGCTCCAA
GGTCCAGAGGCACGCAAGGTGCGTACTAACCCTTCTGGGCGCTGACTGCAGAACCTGCCTCCCC
TCTGCCACTATGAGCGGCTGCTCCAAAAGATGCAGACTCGGGTTCGTGAAATTTGCCCAGACCA
TCTTTAAACTCATCACCGGGACCCTCAGCAAAGACAAGATCGAGGATGATCTGGAGATGACCAT
GGTTTGCCATCGGCCTGAGGGACTGGAGCAGCTTGAGGCACAGACGAACTTCACCAAGAGAGAA
CTGCAAGTCCTTTACCGGGGATTCAAAAACGAGTGCCCCAGTGGTGTGGTTAACGAAGAGACAT
TCAAGCAGATCTACGCTCAGTTTTTCCCTCATGGAGATGCCAGCACATACGCACATTACCTCTT
CAATGCCTTCGACACCACCCAGACAGGCTCTGTAAAGTTCGAGGACTTTGTGACTGCTCTGTCG
ATTTTACTGAGAGGAACGGTCCATGAAAAACTGAGGTGGACGTTTAATTTGTACGACATCAATA
AAGACGGCTACATAAACAAAGAGGAGATGATGGACATAGTGAAAGCCATCTATGACATGATGGG
GAAATACACCTATCCTGTGCTCAAAGAGGACACTCCCAGGCAGCACGTGGACGTCTTCTTCCAG
AAAATGGATAAAAATAAAGATGGCATTGTAACGTTAGACGAATTTCTCGAGTCCTGTCAGGAGG
ATGACAACATCATGAGGTCTCTACAGCTGTTCCAAAATGTCATGTAACTGAGGACACTGGCCAT
CCTGCTCTCAGAGACACTGAAAAACACCTCAATGCCCTGATCTGCCCTTGTTCCAGTTTTACAC
ATCAACTCTCGGGACAGAAATACCTTTTACACTTTGGAAGAATTCTCTGCTGAAGACTTTCTAC
AAAACCTGGCACCGCGTGGCTCAGTCTCTGATTGCCAACTCTTCCTCCCTCCTCCTCTTGAGAG
GGACGAGCTGAAATCCGAAGTTTGTTTTGGAAGCATGCCCATCTCTCCATGCTGCTGCTGCCCT
GTGGAAGGCCCCTCTGCTTGAGCTTAAACAGTAGTGCACAGTTTTCTGCGTATACAGATCCCCA
ACTCACTGCCTCTAAGTCAGGCAGACCCTGATCAATCTGAACCAAATGTGCACCATCCTCCGAT
GGCCTCCCAAGCCAATGTGCCTGCTTCTCTTCCTCTGGTGGGAAGAAAGAACGCTCTACAGAGC
ACTTAGAGCTTACCATGAAAATACTGGGAGAGGCAGCAACTAACATATGTAGAATAGGACTGAA
TTATTAAGCATGGTGGTATCAGATGATGCAAACAGCCCATGTCATTTTTTTTCCAGAGGTAGGG
ACTAATAATTCTCCCACACTAGCACCTACGATCATAGAACAAGTCTTTTAACACATCCAGGAGG
GAAACCGCTGCCCAGTGGTCTATCCCTTCTCTCCATCCCCTGCTCAAGCCCAGCACTGCATGTC
TCTCCCGGAAGGTCCAGAATGCCTGTGAAATGCTGTAACTTTTATACCCTGTTATAATCAATAA
ACAGAACTATTTCGTACACA

hide sequence

RefSeq Acc Id:

NM_001261389 ⟹ NP_001248318

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	18,723,726 - 18,940,809 (-)	NCBI
mRatBN7.2	10	18,219,519 - 18,436,604 (-)	NCBI
Rnor_6.0	10	18,558,128 - 18,784,083 (-)	NCBI
Rnor_5.0	10	18,443,846 - 18,821,334 (-)	NCBI
Celera	10	17,854,471 - 18,068,210 (-)	NCBI

Sequence:

show sequence

ATGGGGGCCGTCATGGGTACCTTCTCGTCCCTGCAGACCAAACAAAGGCGACCCTCTAAAGACA
TCGCCTGGTGGTATTACCAGTATCAGAGAGACAAGATCGAGGATGATCTGGAGATGACCATGGT
TTGCCATCGGCCTGAGGGACTGGAGCAGCTTGAGGCACAGACGAACTTCACCAAGAGAGAACTG
CAAGTCCTTTACCGGGGATTCAAAAACGAGTGCCCCAGTGGTGTGGTTAACGAAGAGACATTCA
AGCAGATCTACGCTCAGTTTTTCCCTCATGGAGATGCCAGCACATACGCACATTACCTCTTCAA
TGCCTTCGACACCACCCAGACAGGCTCTGTAAAGTTCGAGGACTTTGTGACTGCTCTGTCGATT
TTACTGAGAGGAACGGTCCATGAAAAACTGAGGTGGACGTTTAATTTGTACGACATCAATAAAG
ACGGCTACATAAACAAAGAGGAGATGATGGACATAGTGAAAGCCATCTATGACATGATGGGGAA
ATACACCTATCCTGTGCTCAAAGAGGACACTCCCAGGCAGCACGTGGACGTCTTCTTCCAGAAA
ATGGATAAAAATAAAGATGGCATTGTAACGTTAGACGAATTTCTCGAGTCCTGTCAGGAGGATG
ACAACATCATGAGGTCTCTACAGCTGTTCCAAAATGTCATGTAACTGAGGACACTGGCCATCCT
GCTCTCAGAGACACTGAAAAACACCTCAATGCCCTGATCTGCCCTTGTTCCAGTTTTACACATC
AACTCTCGGGACAGAAATACCTTTTACACTTTGGAAGAATTCTCTGCTGAAGACTTTCTACAAA
ACCTGGCACCGCGTGGCTCAGTCTCTGATTGCCAACTCTTCCTCCCTCCTCCTCTTGAGAGGGA
CGAGCTGAAATCCGAAGTTTGTTTTGGAAGCATGCCCATCTCTCCATGCTGCTGCTGCCCTGTG
GAAGGCCCCTCTGCTTGAGCTTAAACAGTAGTGCACAGTTTTCTGCGTATACAGATCCCCAACT
CACTGCCTCTAAGTCAGGCAGACCCTGATCAATCTGAACCAAATGTGCACCATCCTCCGATGGC
CTCCCAAGCCAATGTGCCTGCTTCTCTTCCTCTGGTGGGAAGAAAGAACGCTCTACAGAGCACT
TAGAGCTTACCATGAAAATACTGGGAGAGGCAGCAACTAACATATGTAGAATAGGACTGAATTA
TTAAGCATGGTGGTATCAGATGATGCAAACAGCCCATGTCATTTTTTTTCCAGAGGTAGGGACT
AATAATTCTCCCACACTAGCACCTACGATCATAGAACAAGTCTTTTAACACATCCAGGAGGGAA
ACCGCTGCCCAGTGGTCTATCCCTTCTCTCCATCCCCTGCTCAAGCCCAGCACTGCATGTCTCT
CCCGGAAGGTCCAGAATGCCTGTGAAATGCTGTAACTTTTATACCCTGTTATAATCAATAAACA
GAACTATTTCGTACACA

hide sequence

RefSeq Acc Id:

NM_022929 ⟹ NP_075218

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	18,723,726 - 18,940,809 (-)	NCBI
mRatBN7.2	10	18,219,519 - 18,436,604 (-)	NCBI
Rnor_6.0	10	18,558,128 - 18,784,083 (-)	NCBI
Rnor_5.0	10	18,443,846 - 18,821,334 (-)	NCBI
RGSC_v3.4	10	18,549,984 - 18,565,789 (-)	RGD
Celera	10	17,854,471 - 18,068,210 (-)	NCBI

Sequence:

show sequence

ATGGGGGCCGTCATGGGTACCTTCTCGTCCCTGCAGACCAAACAAAGGCGACCCTCTAAAGACA
AGATCGAGGATGATCTGGAGATGACCATGGTTTGCCATCGGCCTGAGGGACTGGAGCAGCTTGA
GGCACAGACGAACTTCACCAAGAGAGAACTGCAAGTCCTTTACCGGGGATTCAAAAACGAGTGC
CCCAGTGGTGTGGTTAACGAAGAGACATTCAAGCAGATCTACGCTCAGTTTTTCCCTCATGGAG
ATGCCAGCACATACGCACATTACCTCTTCAATGCCTTCGACACCACCCAGACAGGCTCTGTAAA
GTTCGAGGACTTTGTGACTGCTCTGTCGATTTTACTGAGAGGAACGGTCCATGAAAAACTGAGG
TGGACGTTTAATTTGTACGACATCAATAAAGACGGCTACATAAACAAAGAGGAGATGATGGACA
TAGTGAAAGCCATCTATGACATGATGGGGAAATACACCTATCCTGTGCTCAAAGAGGACACTCC
CAGGCAGCACGTGGACGTCTTCTTCCAGAAAATGGATAAAAATAAAGATGGCATTGTAACGTTA
GACGAATTTCTCGAGTCCTGTCAGGAGGATGACAACATCATGAGGTCTCTACAGCTGTTCCAAA
ATGTCATGTAACTGAGGACACTGGCCATCCTGCTCTCAGAGACACTGAAAAACACCTCAATGCC
CTGATCTGCCCTTGTTCCAGTTTTACACATCAACTCTCGGGACAGAAATACCTTTTACACTTTG
GAAGAATTCTCTGCTGAAGACTTTCTACAAAACCTGGCACCGCGTGGCTCAGTCTCTGATTGCC
AACTCTTCCTCCCTCCTCCTCTTGAGAGGGACGAGCTGAAATCCGAAGTTTGTTTTGGAAGCAT
GCCCATCTCTCCATGCTGCTGCTGCCCTGTGGAAGGCCCCTCTGCTTGAGCTTAAACAGTAGTG
CACAGTTTTCTGCGTATACAGATCCCCAACTCACTGCCTCTAAGTCAGGCAGACCCTGATCAAT
CTGAACCAAATGTGCACCATCCTCCGATGGCCTCCCAAGCCAATGTGCCTGCTTCTCTTCCTCT
GGTGGGAAGAAAGAACGCTCTACAGAGCACTTAGAGCTTACCATGAAAATACTGGGAGAGGCAG
CAACTAACATATGTAGAATAGGACTGAATTATTAAGCATGGTGGTATCAGATGATGCAAACAGC
CCATGTCATTTTTTTTCCAGAGGTAGGGACTAATAATTCTCCCACACTAGCACCTACGATCATA
GAACAAGTCTTTTAACACATCCAGGAGGGAAACCGCTGCCCAGTGGTCTATCCCTTCTCTCCAT
CCCCTGCTCAAGCCCAGCACTGCATGTCTCTCCCGGAAGGTCCAGAATGCCTGTGAAATGCTGT
AACTTTTATACCCTGTTATAATCAATAAACAGAACTATTTCGTACACA

hide sequence

RefSeq Acc Id:

XM_006246105 ⟹ XP_006246167

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	18,723,726 - 18,775,105 (-)	NCBI
mRatBN7.2	10	18,219,519 - 18,272,740 (-)	NCBI
Rnor_6.0	10	18,558,132 - 18,616,322 (-)	NCBI
Rnor_5.0	10	18,443,846 - 18,821,334 (-)	NCBI

Sequence:

show sequence

ATTCCTGCTGGCAATCCCAGAGAGTGCACATCCTCACACAGTTGCCAACACTTTATCCAAGAAG
TGGCCCAGATGTTTGTCACTTATCACTCAGTGCAGCTCTGTCCTCACTCTGTCCTCTCAGTGGA
GGTCAGCTGATCCACAGAAATGGAGACTGGGTTCCCCAGAAGTGCAGGACCCTGCAGGAGGTCA
GGTGTCAGGCTTCCCCCTTCAGTACATTGAATACTTTCCCCCAACAAGCTTCCTGCTGGCATTC
TGACTGAAACCTGAACATTTAGAACAACACCGATTTTTATTTTTATTTTTTTGCTTTCCCATAT
TTTATTTCTGGATTGGCTCTTTCCCTGAAGCCCTGGGATCACATGCTCAGCCCGGCCACCAACT
TAACTCCTGACACTCTTAGGGGACTGCCAGAAGACAGATGTAGCTGTGTGTGTGCCCAGTTTCT
GATAACTTCCTTGGCGATCATTTCCAGGGCCACTTCATGATGTCAACGCTAGAATCACTGTATT
CCCATACCAGCTTGTCTGATTTTTCCACTAGGAGAGTAAAAACAAATTGTTAAGGGGGTGGGGG
AGCTTTCATTTTCATGTCTGGGTTTGGTAGCTGAAGCAATCAATGTTCTGTCTTTGAAACGGTG
TACACTGGCACACAACCCCTGGATTCTTCGGAGAATATGCCGTGAGGTGTTGCCAATTATTAGT
TCTCTTGGCTAGCAGATGTTTAGGGACTGGTTAAGCCTTTGGAGAAATTACCTTAGGAAAACGG
GGAAATAAAAGCAAAGATTACCATGAATTGCAAGATTACCTAGCAATTGCAAGGTAGGAGGAGA
GAGGTGGAGGGCGGAGTAGACAGGAGGGAGGGAGAAAGTGAGAGGAAGCTAGGCTGGTGGAAAT
AACCCTGCACTTGGAACAGCGGCAAAGAAGCGCGATTTTCCAGCTTTAAATGCCTGCCCGCGTT
CTGCTTGCCTACCCGGGAACGGAGATGTTGACCCAGGGCGAGTCTGAAGGGCTCCAGACCTTGG
GGATAGTAGTGGTCCTGTGTTCCTCTCTGAAACTACTGCACTACCTCGGGCTGATTGACTTGTC
GGATGACAAGATCGAGGATGATCTGGAGATGACCATGGTTTGCCATCGGCCTGAGGGACTGGAG
CAGCTTGAGGCACAGACGAACTTCACCAAGAGAGAACTGCAAGTCCTTTACCGGGGATTCAAAA
ACGAGTGCCCCAGTGGTGTGGTTAACGAAGAGACATTCAAGCAGATCTACGCTCAGTTTTTCCC
TCATGGAGATGCCAGCACATACGCACATTACCTCTTCAATGCCTTCGACACCACCCAGACAGGC
TCTGTAAAGTTCGAGGACTTTGTGACTGCTCTGTCGATTTTACTGAGAGGAACGGTCCATGAAA
AACTGAGGTGGACGTTTAATTTGTACGACATCAATAAAGACGGCTACATAAACAAAGAGGAGAT
GATGGACATAGTGAAAGCCATCTATGACATGATGGGGAAATACACCTATCCTGTGCTCAAAGAG
GACACTCCCAGGCAGCACGTGGACGTCTTCTTCCAGAAAATGGATAAAAATAAAGATGGCATTG
TAACGTTAGACGAATTTCTCGAGTCCTGTCAGGAGGATGACAACATCATGAGGTCTCTACAGCT
GTTCCAAAATGTCATGTAACTGAGGACACTGGCCATCCTGCTCTCAGAGACACTGAAAAACACC
TCAATGCCCTGATCTGCCCTTGTTCCAGTTTTACACATCAACTCTCGGGACAGAAATACCTTTT
ACACTTTGGAAGAATTCTCTGCTGAAGACTTTCTACAAAACCTGGCACCGCGTGGCTCAGTCTC
TGATTGCCAACTCTTCCTCCCTCCTCCTCTTGAGAGGGACGAGCTGAAATCCGAAGTTTGTTTT
GGAAGCATGCCCATCTCTCCATGCTGCTGCTGCCCTGTGGAAGGCCCCTCTGCTTGAGCTTAAA
CAGTAGTGCACAGTTTTCTGCGTATACAGATCCCCAACTCACTGCCTCTAAGTCAGGCAGACCC
TGATCAATCTGAACCAAATGTGCACCATCCTCCGATGGCCTCCCAAGCCAATGTGCCTGCTTCT
CTTCCTCTGGTGGGAAGAAAGAACGCTCTACAGAGCACTTAGAGCTTACCATGAAAATACTGGG
AGAGGCAGCAACTAACATATGTAGAATAGGACTGAATTATTAAGCATGGTGGTATCAGATGATG
CAAACAGCCCATGTCATTTTTTTTCCAGAGGTAGGGACTAATAATTCTCCCACACTAGCACCTA
CGATCATAGAACAAGTCTTTTAACACATCCAGGAGGGAAACCGCTGCCCAGTGGTCTATCCCTT
CTCTCCATCCCCTGCTCAAGCCCAGCACTGCATGTCTCTCCCGGAAGGTCCAGAATGCCTGTGA
AATGCTGTAACTTTTATACCCTGTTATAATCAATAAACAGAACTATTTCGTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001248316	(Get FASTA)	NCBI Sequence Viewer
	NP_001248317	(Get FASTA)	NCBI Sequence Viewer
	NP_001248318	(Get FASTA)	NCBI Sequence Viewer
	NP_075218	(Get FASTA)	NCBI Sequence Viewer
	XP_006246167	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL92564	(Get FASTA)	NCBI Sequence Viewer
	AAL92565	(Get FASTA)	NCBI Sequence Viewer
	AAN34942	(Get FASTA)	NCBI Sequence Viewer
	BAB03308	(Get FASTA)	NCBI Sequence Viewer
	EDM04075	(Get FASTA)	NCBI Sequence Viewer
	EDM04076	(Get FASTA)	NCBI Sequence Viewer
	EDM04077	(Get FASTA)	NCBI Sequence Viewer
	EDM04078	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007187
	ENSRNOP00000007187.5
	ENSRNOP00000046697
	ENSRNOP00000071584
	ENSRNOP00000074006
	ENSRNOP00000074006.2
	ENSRNOP00000094374
GenBank Protein	Q8R426	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_075218 ⟸ NM_022929
- Peptide Label:	isoform 4
- UniProtKB:	A6HDH0 (UniProtKB/TrEMBL), A0A0G2K701 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGAVMGTFSSLQTKQRRPSKDKIEDDLEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNEC PSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLR WTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTL DEFLESCQEDDNIMRSLQLFQNVM hide sequence

RefSeq Acc Id:	NP_001248317 ⟸ NM_001261388
- Peptide Label:	isoform 2
- UniProtKB:	A0A8I6ALG6 (UniProtKB/TrEMBL), A0A0G2K701 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGCSKRCRLGFVKFAQTIFKLITGTLSKDKIEDDLEMTMVCHRPEGLEQLEAQTNFTKRELQV LYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILL RGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMD KNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM hide sequence

RefSeq Acc Id:	NP_001248316 ⟸ NM_001261387
- Peptide Label:	isoform 1
- UniProtKB:	A0A0H2UHE0 (UniProtKB/TrEMBL), A0A0H2UHY1 (UniProtKB/TrEMBL), A0A0G2K701 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGCSKRCRLGFVKFAQTIFKLITGTLSKDIAWWYYQYQRDKIEDDLEMTMVCHRPEGLEQLEA QTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKF EDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPR QHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM hide sequence

RefSeq Acc Id:	NP_001248318 ⟸ NM_001261389
- Peptide Label:	isoform 3
- UniProtKB:	Q8CIR1 (UniProtKB/Swiss-Prot), Q793P9 (UniProtKB/Swiss-Prot), Q8R425 (UniProtKB/Swiss-Prot), Q8R426 (UniProtKB/Swiss-Prot), A0A0G2K701 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGAVMGTFSSLQTKQRRPSKDIAWWYYQYQRDKIEDDLEMTMVCHRPEGLEQLEAQTNFTKREL QVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSI LLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQK MDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM hide sequence

RefSeq Acc Id:	XP_006246167 ⟸ XM_006246105
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K0U3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPARVLLAYPGTEMLTQGESEGLQTLGIVVVLCSSLKLLHYLGLIDLSDDKIEDDLEMTMVCHR PEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFD TTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTY PVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM hide sequence

Ensembl Acc Id:

ENSRNOP00000071584 ⟸ ENSRNOT00000079031

Ensembl Acc Id:

ENSRNOP00000074006 ⟸ ENSRNOT00000083090

Ensembl Acc Id:

ENSRNOP00000007187 ⟸ ENSRNOT00000007187

Ensembl Acc Id:

ENSRNOP00000046697 ⟸ ENSRNOT00000040737

Ensembl Acc Id:

ENSRNOP00000094374 ⟸ ENSRNOT00000120110

Protein Domains

EF-hand

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8R426-F1-model_v2	AlphaFold	Q8R426	1-227	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:70886	AgrOrtholog
BioCyc Gene	G2FUF-25594	BioCyc
Ensembl Genes	ENSRNOG00000005365	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000007187	ENTREZGENE
	ENSRNOT00000007187.6	UniProtKB/Swiss-Prot
	ENSRNOT00000040737	ENTREZGENE
	ENSRNOT00000079031	ENTREZGENE
	ENSRNOT00000083090	ENTREZGENE
	ENSRNOT00000083090.2	UniProtKB/Swiss-Prot
	ENSRNOT00000120110	ENTREZGENE
Gene3D-CATH	EF-hand	UniProtKB/Swiss-Prot
InterPro	EF-hand-dom_pair	UniProtKB/Swiss-Prot
	EF_Hand_1_Ca_BS	UniProtKB/Swiss-Prot
	EF_hand_dom	UniProtKB/Swiss-Prot
	Recoverin	UniProtKB/Swiss-Prot
KEGG Report	rno:65023	UniProtKB/Swiss-Prot
NCBI Gene	65023	ENTREZGENE
PANTHER	KV CHANNEL-INTERACTING PROTEIN 1	UniProtKB/Swiss-Prot
	PTHR23055	UniProtKB/Swiss-Prot
Pfam	EF-hand_7	UniProtKB/Swiss-Prot
	EF-hand_8	UniProtKB/Swiss-Prot
PhenoGen	Kcnip1	PhenoGen
PRINTS	RECOVERIN	UniProtKB/Swiss-Prot
PROSITE	EF_HAND_1	UniProtKB/Swiss-Prot
	EF_HAND_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000005365	RatGTEx
SMART	EFh	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47473	UniProtKB/Swiss-Prot
UniProt	A0A0G2K0U3	ENTREZGENE, UniProtKB/TrEMBL
	A0A0G2K701	ENTREZGENE, UniProtKB/TrEMBL
	A0A0H2UHE0	ENTREZGENE, UniProtKB/TrEMBL
	A0A0H2UHY1	ENTREZGENE
	A0A8I6ALG6	ENTREZGENE, UniProtKB/TrEMBL
	A6HDH0	ENTREZGENE, UniProtKB/TrEMBL
	A6HDH1_RAT	UniProtKB/TrEMBL
	A6HDH2_RAT	UniProtKB/TrEMBL
	A6HDH3_RAT	UniProtKB/TrEMBL
	KCIP1_RAT	UniProtKB/Swiss-Prot
	Q793P9	ENTREZGENE
	Q8CIR1	ENTREZGENE
	Q8R425	ENTREZGENE
	Q8R426	ENTREZGENE
UniProt Secondary	Q793P9	UniProtKB/Swiss-Prot
	Q8CIR1	UniProtKB/Swiss-Prot
	Q8R425	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-11	Kcnip1	potassium voltage-gated channel interacting protein 1	Kcnip1	Kv channel-interacting protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-07-09	Kcnip1	Kv channel-interacting protein 1			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_process	coexpression of the two splice variants with Kv4.2 channels in oocytes slows the K current decay and destabilizes the open-inactivated channel gating	724600
gene_product	member of the rapidly inactivating K channels in brain and heart	724600

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations