Fndc5 (fibronectin type III domain containing 5) - Rat Genome Database

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Gene: Fndc5 (fibronectin type III domain containing 5) Rattus norvegicus
Analyze
Symbol: Fndc5
Name: fibronectin type III domain containing 5
RGD ID: 708525
Description: Predicted to enable hormone activity. Predicted to be involved in positive regulation of brown fat cell differentiation and response to muscle activity. Predicted to be located in endoplasmic reticulum. Predicted to be active in extracellular region and plasma membrane. Orthologous to human FNDC5 (fibronectin type III domain containing 5); INTERACTS WITH (R)-noradrenaline; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fibronectin type III domain-containing protein 5; LOC260327; peroxisomal protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85146,765,951 - 146,775,611 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5146,751,416 - 146,778,540 (+)EnsemblGRCr8
mRatBN7.25141,481,593 - 141,491,257 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5141,481,590 - 141,490,731 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5144,181,715 - 144,188,750 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05145,951,536 - 145,958,571 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05145,951,004 - 145,958,030 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05147,323,240 - 147,330,266 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5147,323,240 - 147,330,266 (+)Ensemblrn6Rnor6.0
Rnor_5.05151,057,680 - 151,064,707 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45148,296,328 - 148,304,372 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5139,965,061 - 139,970,393 (+)NCBICelera
RGSC_v3.15148,308,143 - 148,312,519 (+)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-noradrenaline  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-bromohexadecanoic acid  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acadesine  (ISO)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (EXP,ISO)
fipronil  (EXP)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
glutathione  (EXP,ISO)
glutathione disulfide  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
indole-3-methanol  (EXP)
lipopolysaccharide  (ISO)
malonaldehyde  (EXP,ISO)
maneb  (ISO)
mercury dibromide  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
propanal  (ISO)
reactive oxygen species  (EXP,ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
streptozocin  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mouse PeP: a novel peroxisomal protein linked to myoblast differentiation and development. Ferrer-Martinez A, etal., Dev Dyn 2002 Jun;224(2):154-67.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12384288   PMID:22237023   PMID:23470775   PMID:23498898   PMID:23593248   PMID:24345335   PMID:24576483   PMID:24930518   PMID:25261800   PMID:25820670   PMID:26054747   PMID:26142757  
PMID:26926562   PMID:26961074   PMID:27177924   PMID:27432282   PMID:28242329   PMID:28394923   PMID:28724742   PMID:28888936   PMID:28890831   PMID:28961497   PMID:29097199   PMID:29182513  
PMID:29303830   PMID:30111257   PMID:30265651   PMID:30569121   PMID:30687746   PMID:30782608   PMID:31085594   PMID:31155748   PMID:31284265   PMID:31578075   PMID:31883222   PMID:31976032  
PMID:31998896   PMID:32200682   PMID:32369414   PMID:32485990   PMID:33508625   PMID:33865997   PMID:34826251   PMID:35106626   PMID:35166002   PMID:35705003   PMID:36161624   PMID:36262283  
PMID:36414561   PMID:38612728   PMID:38708500  


Genomics

Comparative Map Data
Fndc5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85146,765,951 - 146,775,611 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5146,751,416 - 146,778,540 (+)EnsemblGRCr8
mRatBN7.25141,481,593 - 141,491,257 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5141,481,590 - 141,490,731 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5144,181,715 - 144,188,750 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05145,951,536 - 145,958,571 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05145,951,004 - 145,958,030 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05147,323,240 - 147,330,266 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5147,323,240 - 147,330,266 (+)Ensemblrn6Rnor6.0
Rnor_5.05151,057,680 - 151,064,707 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45148,296,328 - 148,304,372 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5139,965,061 - 139,970,393 (+)NCBICelera
RGSC_v3.15148,308,143 - 148,312,519 (+)NCBI
Cytogenetic Map5q36NCBI
FNDC5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38132,862,268 - 32,872,484 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl132,862,268 - 32,872,482 (-)Ensemblhg38GRCh38
GRCh37133,327,869 - 33,338,085 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,100,464 - 33,108,934 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34132,996,969 - 33,005,440NCBI
Celera131,596,509 - 31,606,718 (-)NCBICelera
Cytogenetic Map1p35.1NCBI
HuRef131,443,482 - 31,467,074 (-)NCBIHuRef
CHM1_1133,443,265 - 33,453,515 (-)NCBICHM1_1
T2T-CHM13v2.0132,722,061 - 32,732,277 (-)NCBIT2T-CHM13v2.0
Fndc5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394129,030,672 - 129,038,386 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4129,030,477 - 129,038,386 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384129,136,870 - 129,144,593 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4129,136,999 - 129,144,593 (+)Ensemblmm10GRCm38
MGSCv374128,814,304 - 128,821,837 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364128,639,364 - 128,646,897 (+)NCBIMGSCv36mm8
Celera4127,477,236 - 127,484,769 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.93NCBI
Fndc5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545211,120,823 - 11,126,877 (-)Ensembl
ChiLan1.0NW_00495545211,120,823 - 11,127,010 (-)NCBIChiLan1.0ChiLan1.0
FNDC5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21193,951,370 - 193,959,995 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11193,073,575 - 193,082,199 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0132,152,828 - 32,161,447 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1133,338,886 - 33,347,278 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl133,338,886 - 33,347,284 (-)EnsemblpanPan2panpan1.1
FNDC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,485,941 - 68,493,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,485,935 - 68,492,606 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha265,065,786 - 65,073,356 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0269,051,020 - 69,058,589 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl269,050,613 - 69,057,703 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1265,862,540 - 65,870,105 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,884,983 - 66,892,545 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,876,900 - 67,884,468 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fndc5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505849,940,375 - 49,951,702 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647415,768,518 - 15,783,999 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647415,765,169 - 15,776,452 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FNDC5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl689,163,378 - 89,171,795 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1689,163,363 - 89,171,871 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2683,190,623 - 83,197,348 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FNDC5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12099,997,627 - 100,007,819 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603316,684,569 - 16,693,140 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fndc5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476415,970,991 - 15,976,682 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476415,969,640 - 15,976,683 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fndc5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1128,996,064 - 29,003,346 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fndc5
46 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:80
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000047152
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
AI836596  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85146,775,337 - 146,775,438 (+)Marker Load Pipeline
mRatBN7.25141,490,983 - 141,491,083 (+)MAPPERmRatBN7.2
Rnor_6.05147,330,519 - 147,330,618NCBIRnor6.0
Rnor_5.05151,064,960 - 151,065,059UniSTSRnor5.0
RGSC_v3.45148,304,625 - 148,304,724UniSTSRGSC3.4
Celera5139,970,646 - 139,970,745UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 79 59 6 342 179 11 142 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000047152   ⟹   ENSRNOP00000048830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5146,751,416 - 146,775,610 (+)Ensembl
mRatBN7.2 Ensembl5141,481,590 - 141,490,731 (+)Ensembl
Rnor_6.0 Ensembl5147,323,240 - 147,330,266 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000147403   ⟹   ENSRNOP00000109827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5146,767,955 - 146,774,309 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148889   ⟹   ENSRNOP00000107032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5146,768,002 - 146,778,540 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000169304   ⟹   ENSRNOP00000107335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5146,768,059 - 146,775,085 (+)Ensembl
RefSeq Acc Id: NM_001270981   ⟹   NP_001257910
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85146,768,059 - 146,775,085 (+)NCBI
mRatBN7.25141,483,703 - 141,490,731 (+)NCBI
Rnor_6.05147,323,240 - 147,330,266 (+)NCBI
Rnor_5.05151,057,680 - 151,064,707 (+)NCBI
Celera5139,965,061 - 139,970,393 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109329   ⟹   XP_038965257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85146,765,951 - 146,775,611 (+)NCBI
mRatBN7.25141,481,593 - 141,491,257 (+)NCBI
RefSeq Acc Id: NP_001257910   ⟸   NM_001270981
- Peptide Label: precursor
- Sequence:
Ensembl Acc Id: ENSRNOP00000048830   ⟸   ENSRNOT00000047152
RefSeq Acc Id: XP_038965257   ⟸   XM_039109329
- Peptide Label: isoform X1
- UniProtKB: Q8K3V5 (UniProtKB/Swiss-Prot),   A0A8L2QNJ9 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000107335   ⟸   ENSRNOT00000169304
Ensembl Acc Id: ENSRNOP00000109827   ⟸   ENSRNOT00000147403
Ensembl Acc Id: ENSRNOP00000107032   ⟸   ENSRNOT00000148889
Protein Domains
Fibronectin type-III

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K3V5-F1-model_v2 AlphaFold Q8K3V5 1-209 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708525 AgrOrtholog
BioCyc Gene G2FUF-39819 BioCyc
Ensembl Genes ENSRNOG00000030238 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055027393 UniProtKB/Swiss-Prot
  ENSRNOG00060020839 UniProtKB/Swiss-Prot
  ENSRNOG00065023534 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000047152 ENTREZGENE
  ENSRNOT00000047152.6 UniProtKB/Swiss-Prot
  ENSRNOT00000147403 ENTREZGENE
  ENSRNOT00055047410 UniProtKB/Swiss-Prot
  ENSRNOT00060036102 UniProtKB/Swiss-Prot
  ENSRNOT00065040257 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  FNDC_type_III UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
KEGG Report rno:260327 UniProtKB/Swiss-Prot
NCBI Gene 260327 ENTREZGENE
PANTHER FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 5 UniProtKB/Swiss-Prot
Pfam fn3 UniProtKB/Swiss-Prot
PhenoGen Fndc5 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000030238 RatGTEx
  ENSRNOG00055027393 RatGTEx
  ENSRNOG00060020839 RatGTEx
  ENSRNOG00065023534 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot
UniProt A0A8A2HEV9_RAT UniProtKB/TrEMBL
  A0A8L2QNJ9 ENTREZGENE
  A0ABK0L9E9_RAT UniProtKB/TrEMBL
  A0ABK0LWS7_RAT UniProtKB/TrEMBL
  FNDC5_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A0A8L2QNJ9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Fndc5  fibronectin type III domain containing 5      Name updated 1299863 APPROVED
2004-09-10 Fndc5  peroxisomal protein  LOC260327    Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference