Egfl7 (EGF-like-domain, multiple 7) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Egfl7 (EGF-like-domain, multiple 7) Rattus norvegicus
Analyze
Symbol: Egfl7
Name: EGF-like-domain, multiple 7
RGD ID: 708507
Description: Predicted to enable Notch binding activity. Predicted to be involved in vasculogenesis. Predicted to act upstream of or within negative regulation of Notch signaling pathway; negative regulation of smooth muscle cell migration; and positive regulation of endothelial cell proliferation. Predicted to be located in extracellular space. Predicted to be active in cell surface and extracellular region. Orthologous to human EGFL7 (EGF like domain multiple 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EGF-like domain 7; EGF-like domain-containing protein 7; EGF-like protein 7; epidermal growth factor-like protein 7; Estrogen-regulated protein CBL20 20.4kD; Estrogen-regulated protein CBL20, 20.4kD; LOC245963; MGC93163; multiple EGF-like domain protein 7; multiple EGF-like domains protein 7; multiple epidermal growth factor-like domain protein 7; multiple epidermal growth factor-like domains protein 7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,802,481 - 29,814,966 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl329,802,690 - 29,814,951 (+)EnsemblGRCr8
mRatBN7.239,404,622 - 9,416,879 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,407,520 - 9,416,879 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx312,472,157 - 12,481,498 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0321,055,406 - 21,064,748 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0319,310,727 - 19,320,071 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.034,034,759 - 4,044,280 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,034,921 - 4,043,936 (+)Ensemblrn6Rnor6.0
Rnor_5.039,395,151 - 9,404,528 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.434,760,574 - 4,769,909 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera34,226,855 - 4,236,190 (+)NCBICelera
RGSC_v3.134,760,573 - 4,769,903 (+)NCBI
Cytogenetic Map3p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
crocidolite asbestos  (ISO)
Dibutyl phosphate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
fipronil  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen cyanide  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (EXP)
manganese(II) chloride  (ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
nickel atom  (ISO)
oxaliplatin  (EXP)
oxybenzone  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
potassium cyanide  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
ranitidine  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
tetraphene  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14592969   PMID:15085134   PMID:15162510   PMID:15489334   PMID:20947685   PMID:23658023   PMID:25270395   PMID:38307238  


Genomics

Comparative Map Data
Egfl7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,802,481 - 29,814,966 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl329,802,690 - 29,814,951 (+)EnsemblGRCr8
mRatBN7.239,404,622 - 9,416,879 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,407,520 - 9,416,879 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx312,472,157 - 12,481,498 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0321,055,406 - 21,064,748 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0319,310,727 - 19,320,071 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.034,034,759 - 4,044,280 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,034,921 - 4,043,936 (+)Ensemblrn6Rnor6.0
Rnor_5.039,395,151 - 9,404,528 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.434,760,574 - 4,769,909 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera34,226,855 - 4,236,190 (+)NCBICelera
RGSC_v3.134,760,573 - 4,769,903 (+)NCBI
Cytogenetic Map3p13NCBI
EGFL7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,658,856 - 136,672,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,658,284 - 136,672,679 (+)Ensemblhg38GRCh38
GRCh379139,553,308 - 139,567,130 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,677,198 - 138,686,951 (+)NCBIBuild 36Build 36hg18NCBI36
Celera9110,071,376 - 110,080,865 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,013,481 - 109,027,070 (+)NCBIHuRef
CHM1_19139,701,629 - 139,716,065 (+)NCBICHM1_1
T2T-CHM13v2.09148,891,837 - 148,905,658 (+)NCBIT2T-CHM13v2.0
Egfl7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,471,095 - 26,482,694 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,470,026 - 26,483,132 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38226,581,083 - 26,592,682 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,580,014 - 26,593,120 (+)Ensemblmm10GRCm38
MGSCv37226,436,576 - 26,448,202 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36226,403,092 - 26,414,691 (+)NCBIMGSCv36mm8
Celera226,298,030 - 26,309,768 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.95NCBI
Egfl7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555134,142,108 - 4,151,421 (-)Ensembl
ChiLan1.0NW_0049555134,145,059 - 4,154,918 (-)NCBIChiLan1.0ChiLan1.0
EGFL7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,711,328 - 2,720,808 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,713,663 - 2,723,143 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,735,192 - 107,748,729 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,708,783 - 136,722,448 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9136,708,783 - 136,722,448 (+)EnsemblpanPan2panpan1.1
EGFL7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,878,075 - 48,890,002 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,878,075 - 48,895,541 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha948,129,694 - 48,141,461 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0949,755,437 - 49,767,214 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,755,437 - 49,764,622 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,536,580 - 48,548,343 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,830,177 - 48,841,898 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,877,667 - 48,889,423 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Egfl7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,166,558 - 202,175,648 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366691,198,035 - 1,208,274 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366691,199,416 - 1,211,367 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EGFL7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21313,730,119 - 313,736,346 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EGFL7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,525,615 - 1,535,024 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660583,733,443 - 3,742,885 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Egfl7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,738,942 - 1,746,226 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247601,737,001 - 1,746,496 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Egfl7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1510,495,541 - 10,503,126 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Egfl7
119 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:58
Interacting mature miRNAs:65
Transcripts:ENSRNOT00000026318
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat

Markers in Region
RH141414  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.239,416,539 - 9,416,745 (+)MAPPERmRatBN7.2
Rnor_6.034,043,941 - 4,044,146NCBIRnor6.0
Rnor_5.039,404,189 - 9,404,394UniSTSRnor5.0
RGSC_v3.434,769,570 - 4,769,775UniSTSRGSC3.4
Celera34,235,851 - 4,236,056UniSTS
Cytogenetic Map3p13UniSTS
RH141422  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.239,416,883 - 9,417,082 (+)MAPPERmRatBN7.2
Rnor_6.034,044,285 - 4,044,483NCBIRnor6.0
Rnor_5.039,404,533 - 9,404,731UniSTSRnor5.0
RGSC_v3.434,769,914 - 4,770,112UniSTSRGSC3.4
Celera34,236,195 - 4,236,393UniSTS
Cytogenetic Map3p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 85 59 6 349 185 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000026318   ⟹   ENSRNOP00000026318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl329,805,593 - 29,814,950 (+)Ensembl
mRatBN7.2 Ensembl39,407,520 - 9,416,535 (+)Ensembl
Rnor_6.0 Ensembl34,034,921 - 4,043,936 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107620   ⟹   ENSRNOP00000088876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl329,808,363 - 29,814,951 (+)Ensembl
mRatBN7.2 Ensembl39,412,696 - 9,416,879 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111558   ⟹   ENSRNOP00000087847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl39,410,394 - 9,416,879 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115008   ⟹   ENSRNOP00000081631
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl329,802,690 - 29,814,950 (+)Ensembl
mRatBN7.2 Ensembl39,410,259 - 9,416,419 (+)Ensembl
RefSeq Acc Id: NM_001399187   ⟹   NP_001386116
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,805,631 - 29,814,966 (+)NCBI
mRatBN7.239,407,544 - 9,416,879 (+)NCBI
RefSeq Acc Id: NM_001399188   ⟹   NP_001386117
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,808,301 - 29,814,966 (+)NCBI
mRatBN7.239,410,214 - 9,416,879 (+)NCBI
RefSeq Acc Id: NR_174164
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,805,631 - 29,814,966 (+)NCBI
mRatBN7.239,407,544 - 9,416,879 (+)NCBI
RefSeq Acc Id: XM_039104248   ⟹   XP_038960176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,802,481 - 29,814,966 (+)NCBI
mRatBN7.239,404,622 - 9,416,536 (+)NCBI
Ensembl Acc Id: ENSRNOP00000026318   ⟸   ENSRNOT00000026318
RefSeq Acc Id: XP_038960176   ⟸   XM_039104248
- Peptide Label: isoform X1
- UniProtKB: Q9JKW3 (UniProtKB/Swiss-Prot),   Q6AZ60 (UniProtKB/Swiss-Prot),   A0A8L2QF53 (UniProtKB/TrEMBL),   A6JTF9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000087847   ⟸   ENSRNOT00000111558
Ensembl Acc Id: ENSRNOP00000088876   ⟸   ENSRNOT00000107620
Ensembl Acc Id: ENSRNOP00000081631   ⟸   ENSRNOT00000115008
RefSeq Acc Id: NP_001386116   ⟸   NM_001399187
- Peptide Label: precursor
- UniProtKB: Q9JKW3 (UniProtKB/Swiss-Prot),   Q6AZ60 (UniProtKB/Swiss-Prot),   A0A8L2QF53 (UniProtKB/TrEMBL),   A6JTF9 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386117   ⟸   NM_001399188
- Peptide Label: precursor
- UniProtKB: Q9JKW3 (UniProtKB/Swiss-Prot),   Q6AZ60 (UniProtKB/Swiss-Prot),   A0A8L2QF53 (UniProtKB/TrEMBL),   A6JTF9 (UniProtKB/TrEMBL)
Protein Domains
EGF-like   EMI

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AZ60-F1-model_v2 AlphaFold Q6AZ60 1-279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691909
Promoter ID:EPDNEW_R2434
Type:single initiation site
Name:Egfl7_1
Description:EGF-like-domain, multiple 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.034,034,907 - 4,034,967EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708507 AgrOrtholog
BioCyc Gene G2FUF-50366 BioCyc
Ensembl Genes ENSRNOG00000019388 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000026318 ENTREZGENE
  ENSRNOT00000107620 ENTREZGENE
  ENSRNOT00000115008 ENTREZGENE
Gene3D-CATH Laminin UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7127696 IMAGE-MGC_LOAD
InterPro Dev_Signal_Modulators UniProtKB/Swiss-Prot
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot
  EGF_extracell UniProtKB/Swiss-Prot
  EMI_domain UniProtKB/Swiss-Prot
  NOTCH1_EGF-like UniProtKB/Swiss-Prot
MGC_CLONE MGC:93163 IMAGE-MGC_LOAD
NCBI Gene 245963 ENTREZGENE
PANTHER EGF-LIKE-DOMAIN, MULTIPLE 7, 8 UniProtKB/Swiss-Prot
  EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 7 UniProtKB/Swiss-Prot
Pfam EGF_2 UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  EMI UniProtKB/Swiss-Prot
PhenoGen Egfl7 PhenoGen
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot
  EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  EMI UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019388 RatGTEx
SMART EGF UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot
UniProt A0A8I5ZSM0_RAT UniProtKB/TrEMBL
  A0A8I6A5Y9_RAT UniProtKB/TrEMBL
  A0A8L2QF53 ENTREZGENE, UniProtKB/TrEMBL
  A6JTF8_RAT UniProtKB/TrEMBL
  A6JTF9 ENTREZGENE, UniProtKB/TrEMBL
  A6JTG0_RAT UniProtKB/TrEMBL
  A6JTG1_RAT UniProtKB/TrEMBL
  A6JTG2_RAT UniProtKB/TrEMBL
  A6JTG3_RAT UniProtKB/TrEMBL
  EGFL7_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JKW3 ENTREZGENE
UniProt Secondary Q9JKW3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-25 Egfl7  EGF-like-domain, multiple 7  Egfl7  EGF-like domain 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Egfl7  EGF-like domain 7  LOC245963  Estrogen-regulated protein CBL20, 20.4kD  Symbol and Name updated 1299863 APPROVED