Zng1a (Zn regulated GTPase metalloprotein activator 1A) - Rat Genome Database

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Gene: Zng1a (Zn regulated GTPase metalloprotein activator 1A) Rattus norvegicus
Analyze
Symbol: Zng1a
Name: Zn regulated GTPase metalloprotein activator 1A
RGD ID: 708495
Description: Predicted to enable GTPase activity and zinc chaperone activity. Predicted to be involved in intracellular zinc ion homeostasis and kidney development. Predicted to act upstream of or within protein maturation. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to several human genes including ZNG1A (Zn regulated GTPase metalloprotein activator 1A); ZNG1C (Zn regulated GTPase metalloprotein activator 1C); and ZNG1E (Zn regulated GTPase metalloprotein activator 1E); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Cbwd1; cobalamin synthase W domain-containing protein 1; cobalamin synthetase W domain-containing protein 1; COBW domain containing 1; COBW domain-containing protein 1; dopamine responsive protein; LOC171057; zinc-regulated GTPase metalloprotein activator 1; Zng1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81231,994,651 - 232,039,314 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1231,991,118 - 232,036,998 (-)EnsemblGRCr8
mRatBN7.21222,568,278 - 222,612,937 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1222,564,545 - 222,610,629 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1231,021,390 - 231,063,008 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01237,951,468 - 237,993,086 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01230,769,819 - 230,811,366 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01242,819,383 - 242,861,792 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1242,819,390 - 242,861,767 (-)Ensemblrn6Rnor6.0
Rnor_5.01250,092,601 - 250,135,008 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41228,360,614 - 228,402,151 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1219,772,105 - 219,813,419 (-)NCBICelera
RGSC_v3.11228,524,471 - 228,566,229 (-)NCBI
Cytogenetic Map1q51NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
CAKUT  (ISS)
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
nucleus  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Identification of dopamine responsive mRNAs in glial cells by suppression subtractive hybridization. Shi J, etal., Brain Res 2001 Aug 10;910(1-2):29-37.
Additional References at PubMed
PMID:12477932   PMID:15489334  


Genomics

Comparative Map Data
Zng1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81231,994,651 - 232,039,314 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1231,991,118 - 232,036,998 (-)EnsemblGRCr8
mRatBN7.21222,568,278 - 222,612,937 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1222,564,545 - 222,610,629 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1231,021,390 - 231,063,008 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01237,951,468 - 237,993,086 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01230,769,819 - 230,811,366 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01242,819,383 - 242,861,792 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1242,819,390 - 242,861,767 (-)Ensemblrn6Rnor6.0
Rnor_5.01250,092,601 - 250,135,008 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41228,360,614 - 228,402,151 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1219,772,105 - 219,813,419 (-)NCBICelera
RGSC_v3.11228,524,471 - 228,566,229 (-)NCBI
Cytogenetic Map1q51NCBI
ZNG1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389120,837 - 179,056 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9119,288 - 179,147 (-)Ensemblhg38GRCh38
GRCh379120,837 - 179,056 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369111,038 - 169,075 (-)NCBIBuild 36Build 36hg18NCBI36
Build 349111,040 - 169,032NCBI
Cytogenetic Map9p24.3NCBI
HuRef2106,672,901 - 106,677,762 (+)NCBIHuRef
CHM1_19121,375 - 179,473 (-)NCBICHM1_1
T2T-CHM13v2.09114,953 - 173,385 (-)NCBIT2T-CHM13v2.0
Zng1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391924,897,280 - 24,939,024 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1924,897,280 - 24,938,974 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381924,919,629 - 24,961,663 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1924,919,916 - 24,961,610 (-)Ensemblmm10GRCm38
MGSCv371924,994,406 - 25,036,106 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361924,987,524 - 25,028,655 (-)NCBIMGSCv36mm8
Celera1925,688,193 - 25,733,766 (-)NCBICelera
Cytogenetic Map19BNCBI
cM Map1919.86NCBI
Zng1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554344,732,767 - 4,780,884 (-)Ensembl
ChiLan1.0NW_0049554344,732,584 - 4,780,990 (-)NCBIChiLan1.0ChiLan1.0
ZNG1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211124,389,638 - 124,436,514 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19124,395,666 - 124,437,054 (+)NCBINHGRI_mPanPan1
ZNG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1189,063,511 - 89,120,995 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl189,063,511 - 89,121,360 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha189,534,015 - 89,591,481 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0189,613,458 - 89,670,966 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl189,613,462 - 89,670,926 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1189,259,543 - 89,317,221 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0188,971,436 - 89,029,258 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0189,732,287 - 89,790,024 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Zng1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947136,522,175 - 136,564,617 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365034,608,402 - 4,650,855 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365034,608,382 - 4,650,822 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11221,521,313 - 221,570,992 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21247,781,685 - 247,828,125 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNG1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11279,335,976 - 79,387,793 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603867,735,528 - 67,787,724 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zng1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247364,878,241 - 4,934,000 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Zng1a
418 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:20
Count of miRNA genes:19
Interacting mature miRNAs:20
Transcripts:ENSRNOT00000021185
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367243666627Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1207243873252243873Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
5508828Leukc3Leukocyte quantity QTL 3eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)1227535119233480676Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1223964326248681945Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1226175591270518180Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1218829748263829748Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1193964073238964073Rat
8693661Alc34Alcohol consumption QTL 342.20.611drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367238041033Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1194575422239575422Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1193400541238400541Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1223134011262090599Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1207243873252243873Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1202543537247543537Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1225108840270108840Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1228180370266453608Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1207243873252243873Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1224633915269633915Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228180243255849249Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1221820316234540296Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1192995199237995199Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1201464383246464383Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1197807365233480676Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1193400541238400541Rat
634340Hcar5Hepatocarcinoma resistance QTL 58liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1223964326236074012Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1207099883252099883Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
8693618Alc25Alcohol consumption QTL 2530.28drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367238041033Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1191260175236260175Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1226175591270518180Rat
2325727Pia41Pristane induced arthritis QTL 41joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1188241285233241285Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1228174566270518180Rat

Markers in Region
MARC_16905-16906:1020714896:3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21222,593,734 - 222,594,192 (+)MAPPERmRatBN7.2
Rnor_6.01242,844,838 - 242,845,295NCBIRnor6.0
Rnor_5.01250,118,056 - 250,118,513UniSTSRnor5.0
RGSC_v3.41228,385,309 - 228,385,766UniSTSRGSC3.4
Celera1219,796,800 - 219,797,257UniSTS
Cytogenetic Map1q51UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 91 59 6 355 191 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_133535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF353305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH772044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000021185   ⟹   ENSRNOP00000021185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1231,995,244 - 232,036,998 (-)Ensembl
mRatBN7.2 Ensembl1222,568,278 - 222,610,629 (-)Ensembl
Rnor_6.0 Ensembl1242,819,390 - 242,861,767 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1242,832,102 - 242,837,849 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104262   ⟹   ENSRNOP00000097012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1231,995,244 - 232,036,998 (-)Ensembl
mRatBN7.2 Ensembl1222,568,278 - 222,610,629 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105156   ⟹   ENSRNOP00000087771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1231,995,244 - 232,036,998 (-)Ensembl
mRatBN7.2 Ensembl1222,568,278 - 222,610,629 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108052   ⟹   ENSRNOP00000081860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1231,995,244 - 232,036,998 (-)Ensembl
mRatBN7.2 Ensembl1222,568,278 - 222,610,629 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117595   ⟹   ENSRNOP00000081535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1231,991,118 - 232,036,998 (-)Ensembl
mRatBN7.2 Ensembl1222,564,545 - 222,610,611 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120079   ⟹   ENSRNOP00000088617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1231,995,244 - 232,036,998 (-)Ensembl
mRatBN7.2 Ensembl1222,568,278 - 222,610,629 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129537   ⟹   ENSRNOP00000109582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1231,995,244 - 232,036,998 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000153445   ⟹   ENSRNOP00000099850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1231,995,244 - 232,036,998 (-)Ensembl
RefSeq Acc Id: NM_133535   ⟹   NP_598219
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,995,411 - 232,036,943 (-)NCBI
mRatBN7.21222,569,038 - 222,610,574 (-)NCBI
Rnor_6.01242,820,143 - 242,861,717 (-)NCBI
Rnor_5.01250,092,601 - 250,135,008 (-)NCBI
RGSC_v3.41228,360,614 - 228,402,151 (-)RGD
Celera1219,772,105 - 219,813,419 (-)RGD
Sequence:
RefSeq Acc Id: XM_006231191   ⟹   XP_006231253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,994,651 - 232,037,051 (-)NCBI
mRatBN7.21222,568,278 - 222,610,694 (-)NCBI
Rnor_6.01242,819,383 - 242,861,792 (-)NCBI
Rnor_5.01250,092,601 - 250,135,008 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006231192   ⟹   XP_006231254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,994,651 - 232,037,051 (-)NCBI
mRatBN7.21222,568,278 - 222,610,694 (-)NCBI
Rnor_6.01242,819,383 - 242,861,792 (-)NCBI
Rnor_5.01250,092,601 - 250,135,008 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006231193   ⟹   XP_006231255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,994,651 - 232,037,052 (-)NCBI
mRatBN7.21222,568,278 - 222,610,694 (-)NCBI
Rnor_6.01242,819,383 - 242,861,792 (-)NCBI
Rnor_5.01250,092,601 - 250,135,008 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086091   ⟹   XP_038942019
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,994,651 - 232,039,314 (-)NCBI
mRatBN7.21222,568,278 - 222,612,937 (-)NCBI
RefSeq Acc Id: XM_063273586   ⟹   XP_063129656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,994,651 - 232,037,050 (-)NCBI
RefSeq Acc Id: XM_063273627   ⟹   XP_063129697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,994,651 - 232,037,051 (-)NCBI
RefSeq Acc Id: XM_063273716   ⟹   XP_063129786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,994,651 - 232,037,052 (-)NCBI
RefSeq Acc Id: XM_063273745   ⟹   XP_063129815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,007,900 - 232,037,089 (-)NCBI
RefSeq Acc Id: XR_010057529
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,997,638 - 232,037,089 (-)NCBI
RefSeq Acc Id: XR_010057544
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81231,997,479 - 232,037,089 (-)NCBI
RefSeq Acc Id: NP_598219   ⟸   NM_133535
- UniProtKB: Q5RK12 (UniProtKB/Swiss-Prot),   Q99MB4 (UniProtKB/Swiss-Prot),   A0A8I6GGE7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231255   ⟸   XM_006231193
- Peptide Label: isoform X6
- UniProtKB: A0A8I6GGE7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231254   ⟸   XM_006231192
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AN13 (UniProtKB/TrEMBL),   A0A8I6GGE7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231253   ⟸   XM_006231191
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A519 (UniProtKB/TrEMBL),   A0A8I6GGE7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021185   ⟸   ENSRNOT00000021185
RefSeq Acc Id: XP_038942019   ⟸   XM_039086091
- Peptide Label: isoform X8
Ensembl Acc Id: ENSRNOP00000097012   ⟸   ENSRNOT00000104262
Ensembl Acc Id: ENSRNOP00000081535   ⟸   ENSRNOT00000117595
Ensembl Acc Id: ENSRNOP00000081860   ⟸   ENSRNOT00000108052
Ensembl Acc Id: ENSRNOP00000087771   ⟸   ENSRNOT00000105156
Ensembl Acc Id: ENSRNOP00000088617   ⟸   ENSRNOT00000120079
RefSeq Acc Id: XP_063129786   ⟸   XM_063273716
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GGE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129697   ⟸   XM_063273627
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GGE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129656   ⟸   XM_063273586
- Peptide Label: isoform X1
- UniProtKB: A6I0R1 (UniProtKB/TrEMBL),   A0A8I6GGE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129815   ⟸   XM_063273745
- Peptide Label: isoform X7
- UniProtKB: A6I0R2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000099850   ⟸   ENSRNOT00000153445
Ensembl Acc Id: ENSRNOP00000109582   ⟸   ENSRNOT00000129537
Protein Domains
CobW C-terminal   CobW/HypB/UreG nucleotide-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99MB4-F1-model_v2 AlphaFold Q99MB4 1-394 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690829
Promoter ID:EPDNEW_R1354
Type:initiation region
Name:Cbwd1_1
Description:COBW domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01242,861,772 - 242,861,832EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708495 AgrOrtholog
BioCyc Gene G2FUF-56086 BioCyc
Ensembl Genes ENSRNOG00000015516 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021185 ENTREZGENE
  ENSRNOT00000021185.8 UniProtKB/Swiss-Prot
  ENSRNOT00000104262 ENTREZGENE
  ENSRNOT00000105156 ENTREZGENE
  ENSRNOT00000108052 ENTREZGENE
  ENSRNOT00000153445 ENTREZGENE
Gene3D-CATH 3.30.1220.10 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7135348 IMAGE-MGC_LOAD
InterPro Cbl_biosynth_CobW-like_C UniProtKB/Swiss-Prot
  CobW-likC_sf UniProtKB/Swiss-Prot
  CobW/HypB/UreG_dom UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Zinc-reg_GTPase_activator UniProtKB/Swiss-Prot
KEGG Report rno:171057 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105334 IMAGE-MGC_LOAD
NCBI Gene 171057 ENTREZGENE
PANTHER COBW DOMAIN-CONTAINING PROTEIN 1-RELATED UniProtKB/Swiss-Prot
  COBW-RELATED UniProtKB/Swiss-Prot
Pfam cobW UniProtKB/Swiss-Prot
  CobW_C UniProtKB/Swiss-Prot
PhenoGen Zng1a PhenoGen
RatGTEx ENSRNOG00000015516 RatGTEx
Superfamily-SCOP Hypothetical protein YjiA, C-terminal domain UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I5ZS75_RAT UniProtKB/TrEMBL
  A0A8I5ZTT4_RAT UniProtKB/TrEMBL
  A0A8I6A519 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AN13 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GGE7 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0KY69_RAT UniProtKB/TrEMBL
  A0ABK0LU08_RAT UniProtKB/TrEMBL
  A6I0R1 ENTREZGENE, UniProtKB/TrEMBL
  A6I0R2 ENTREZGENE, UniProtKB/TrEMBL
  CBWD1_RAT UniProtKB/Swiss-Prot
  Q5RK12 ENTREZGENE
  Q99MB4 ENTREZGENE
UniProt Secondary Q5RK12 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-27 Zng1a  Zn regulated GTPase metalloprotein activator 1A  Cbwd1  COBW domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Cbwd1  COBW domain containing 1  LOC171057  dopamine responsive protein  Symbol and Name updated 1299863 APPROVED