Ddx46 (DEAD-box helicase 46) - Rat Genome Database

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Gene: Ddx46 (DEAD-box helicase 46) Rattus norvegicus
Analyze
Symbol: Ddx46
Name: DEAD-box helicase 46
RGD ID: 708480
Description: Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in U2-type prespliceosome assembly. Predicted to be located in Cajal body and nuclear speck. Predicted to be part of U2-type spliceosomal complex. Predicted to be active in nucleus. Orthologous to human DDX46 (DEAD-box helicase 46); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; DEAD box protein 46; helicase of 117.4 kDa; LOC245957; probable ATP-dependent RNA helicase DDX46; RNA helicase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,947,237 - 8,993,705 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl178,947,237 - 8,990,247 (-)EnsemblGRCr8
mRatBN7.2178,942,070 - 8,988,440 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,944,454 - 8,988,439 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx178,957,611 - 9,003,632 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01710,487,079 - 10,533,228 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0178,954,003 - 9,000,024 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,475,275 - 9,519,545 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,475,538 - 9,519,595 (-)Ensemblrn6Rnor6.0
Rnor_5.01711,582,729 - 11,626,991 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41714,985,633 - 15,029,607 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera179,026,373 - 9,070,389 (-)NCBICelera
RGSC_v3.11714,985,632 - 15,029,607 (-)NCBI
Cytogenetic Map17p14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
allethrin  (EXP)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (EXP)
cylindrospermopsin  (ISO)
cypermethrin  (EXP)
cyproconazole  (ISO)
deoxynivalenol  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
formaldehyde  (ISO)
gentamycin  (EXP)
haloperidol  (ISO)
hydralazine  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
ivermectin  (ISO)
methapyrilene  (EXP)
ozone  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
propiconazole  (ISO)
pyrethrins  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triadimefon  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functions of the DExD/H-box proteins in nuclear pre-mRNA splicing. Chang TH, etal., Biochim Biophys Acta. 2013 Aug;1829(8):764-74. doi: 10.1016/j.bbagrm.2013.02.006. Epub 2013 Feb 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. A putative mammalian RNA helicase with an arginine-serine-rich domain colocalizes with a splicing factor. Sukegawa J and Blobel G, J Biol Chem 1995 Jun 30;270(26):15702-6.
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:16791210   PMID:22681889   PMID:31505169  


Genomics

Comparative Map Data
Ddx46
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,947,237 - 8,993,705 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl178,947,237 - 8,990,247 (-)EnsemblGRCr8
mRatBN7.2178,942,070 - 8,988,440 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,944,454 - 8,988,439 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx178,957,611 - 9,003,632 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01710,487,079 - 10,533,228 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0178,954,003 - 9,000,024 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,475,275 - 9,519,545 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,475,538 - 9,519,595 (-)Ensemblrn6Rnor6.0
Rnor_5.01711,582,729 - 11,626,991 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41714,985,633 - 15,029,607 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera179,026,373 - 9,070,389 (-)NCBICelera
RGSC_v3.11714,985,632 - 15,029,607 (-)NCBI
Cytogenetic Map17p14NCBI
DDX46
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385134,758,779 - 134,831,121 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5134,758,771 - 134,831,121 (+)Ensemblhg38GRCh38
GRCh375134,094,469 - 134,166,811 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365134,122,360 - 134,194,710 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345134,122,359 - 134,194,708NCBI
Celera5130,220,831 - 130,294,505 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5129,280,020 - 129,353,042 (+)NCBIHuRef
CHM1_15133,527,063 - 133,599,436 (+)NCBICHM1_1
T2T-CHM13v2.05135,284,406 - 135,358,072 (+)NCBIT2T-CHM13v2.0
Ddx46
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391355,782,790 - 55,829,080 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1355,782,841 - 55,829,069 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381355,634,975 - 55,681,267 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1355,635,027 - 55,681,256 (+)Ensemblmm10GRCm38
MGSCv371355,736,388 - 55,782,617 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361355,644,673 - 55,688,737 (+)NCBIMGSCv36mm8
Celera1356,689,234 - 56,735,498 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.06NCBI
Ddx46
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540829,981,229 - 30,031,473 (+)Ensembl
ChiLan1.0NW_00495540829,981,509 - 30,031,473 (+)NCBIChiLan1.0ChiLan1.0
DDX46
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24130,054,133 - 130,126,128 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15128,193,694 - 128,266,348 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05130,185,793 - 130,232,208 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15136,302,356 - 136,375,992 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5136,302,356 - 136,375,992 (+)EnsemblpanPan2panpan1.1
DDX46
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,834,843 - 22,906,976 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,833,926 - 22,905,964 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1121,583,883 - 21,656,884 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01123,641,148 - 23,714,301 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1123,640,644 - 23,714,307 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,340,290 - 22,413,564 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01122,206,581 - 22,279,270 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,848,522 - 22,921,627 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
DDX46
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2136,972,507 - 137,030,430 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12136,972,504 - 137,030,186 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22142,588,602 - 142,644,674 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX46
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12337,547,227 - 37,613,632 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603440,299,339 - 40,374,103 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx46
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473312,230,678 - 12,294,258 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473312,229,562 - 12,294,301 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ddx46
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11473,956,272 - 73,998,809 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ddx46
293 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:125
Count of miRNA genes:95
Interacting mature miRNAs:104
Transcripts:ENSRNOT00000029885
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
1581553Pur14Proteinuria QTL 145.30.0001urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)17798524316523460Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17857434232199534Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat

Markers in Region
RH134219  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,944,582 - 8,944,773 (+)MAPPERmRatBN7.2
Rnor_6.0179,475,661 - 9,475,851NCBIRnor6.0
Rnor_5.01711,583,113 - 11,583,303UniSTSRnor5.0
RGSC_v3.41714,985,754 - 14,985,944UniSTSRGSC3.4
Celera179,026,494 - 9,026,684UniSTS
Cytogenetic Map17p14UniSTS
BE109072  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera98,835,297 - 8,835,480UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000029885   ⟹   ENSRNOP00000030772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,944,462 - 8,988,439 (-)Ensembl
Rnor_6.0 Ensembl179,475,538 - 9,519,595 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114045   ⟹   ENSRNOP00000088007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl178,947,237 - 8,990,247 (-)Ensembl
mRatBN7.2 Ensembl178,944,454 - 8,985,084 (-)Ensembl
RefSeq Acc Id: NM_001395621   ⟹   NP_001382550
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,947,237 - 8,993,603 (-)NCBI
mRatBN7.2178,942,070 - 8,988,440 (-)NCBI
RefSeq Acc Id: NM_139098   ⟹   NP_620798
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,947,237 - 8,993,603 (-)NCBI
mRatBN7.2178,942,070 - 8,988,440 (-)NCBI
Rnor_6.0179,475,540 - 9,519,514 (-)NCBI
Rnor_5.01711,582,729 - 11,626,991 (-)NCBI
RGSC_v3.41714,985,633 - 15,029,607 (-)RGD
Celera179,026,373 - 9,070,389 (-)RGD
Sequence:
RefSeq Acc Id: XM_063276054   ⟹   XP_063132124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,949,620 - 8,993,705 (-)NCBI
RefSeq Acc Id: XM_063276055   ⟹   XP_063132125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,949,620 - 8,993,705 (-)NCBI
RefSeq Acc Id: XR_010058808
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,966,335 - 8,993,705 (-)NCBI
RefSeq Acc Id: NP_620798   ⟸   NM_139098
- Peptide Label: isoform 1
- UniProtKB: Q62780 (UniProtKB/Swiss-Prot),   A0A8I6A8E8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030772   ⟸   ENSRNOT00000029885
Ensembl Acc Id: ENSRNOP00000088007   ⟸   ENSRNOT00000114045
RefSeq Acc Id: NP_001382550   ⟸   NM_001395621
- Peptide Label: isoform 2
- UniProtKB: A0A8I6A8E8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132125   ⟸   XM_063276055
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A8E8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132124   ⟸   XM_063276054
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A8E8 (UniProtKB/TrEMBL)
Protein Domains
DEAD-box RNA helicase Q   Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62780-F1-model_v2 AlphaFold Q62780 1-1032 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700296
Promoter ID:EPDNEW_R10819
Type:multiple initiation site
Name:Ddx46_1
Description:DEAD-box helicase 46
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0179,519,528 - 9,519,588EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708480 AgrOrtholog
BioCyc Gene G2FUF-10220 BioCyc
Ensembl Genes ENSRNOG00000021637 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000114045 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7461248 IMAGE-MGC_LOAD
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  PRP5/DDX46/KHDC4_KH UniProtKB/Swiss-Prot
  RNA-helicase_DEAD-box_CS UniProtKB/Swiss-Prot
  RNA_helicase_DEAD_Q_motif UniProtKB/Swiss-Prot
KEGG Report rno:245957 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124939 IMAGE-MGC_LOAD
NCBI Gene 245957 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DBP3 UniProtKB/Swiss-Prot
Pfam DEAD UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  KH_12 UniProtKB/Swiss-Prot
PhenoGen Ddx46 PhenoGen
PROSITE DEAD_ATP_HELICASE UniProtKB/Swiss-Prot
  HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
  Q_MOTIF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000021637 RatGTEx
SMART DEXDc UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I6A8E8 ENTREZGENE, UniProtKB/TrEMBL
  A6KAQ1_RAT UniProtKB/TrEMBL
  DDX46_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Ddx46  DEAD-box helicase 46  Ddx46  DEAD (Asp-Glu-Ala-Asp) box polypeptide 46  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ddx46  DEAD (Asp-Glu-Ala-Asp) box polypeptide 46    RNA helicase  Name updated 1299863 APPROVED
2004-09-10 Ddx46  RNA helicase  LOC245957    Symbol and Name updated 1299863 APPROVED