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Gene: Ppp6c (protein phosphatase 6, catalytic subunit) Rattus norvegicus

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Symbol:

Ppp6c

Name:

protein phosphatase 6, catalytic subunit

RGD ID:

708460

Description:

Enables protein serine/threonine phosphatase activity. Involved in protein dephosphorylation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human PPP6C (protein phosphatase 6 catalytic subunit); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione; ammonium chloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC171121; MGC93213; PP-V; PP6C; protein phosphatase V; serine/threonine-protein phosphatase 6 catalytic subunit

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PPP6C (protein phosphatase 6 catalytic subunit)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ppp6c (protein phosphatase 6, catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ppp6c (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PPP6C (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PPP6C (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ppp6c (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PPP6C (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PPP6C (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ppp6c (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TAF3 (TATA-box binding protein associated factor 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PPP6C (protein phosphatase 6 catalytic subunit)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ppp6c (protein phosphatase 6, catalytic subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ppp6c (protein phosphatase 6, catalytic subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pph-6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	PpV	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SIT4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ppp6c	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	43,339,521 - 43,371,807 (-)	NCBI		GRCr8
mRatBN7.2	3	22,929,816 - 22,962,123 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	22,931,577 - 22,962,113 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	26,399,878 - 26,430,642 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	34,984,867 - 35,015,633 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	32,797,655 - 32,828,524 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	23,478,123 - 23,510,959 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	23,480,266 - 23,510,959 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	28,702,120 - 28,732,821 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	18,966,289 - 18,997,796 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	18,862,668 - 18,894,168 (-)	NCBI
Celera	3	21,363,667 - 21,394,395 (-)	NCBI		Celera
Cytogenetic Map	3	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ppp6c	Rat	basal cell carcinoma		ISO	PPP6C (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:26950094
Ppp6c	Rat	melanoma		ISO	PPP6C (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:22842228

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ppp6c	Rat	1,2-dimethylhydrazine	decreases expression	ISO	Ppp6c (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in decreased expression of PPP6C mRNA	CTD	PMID:22206623
Ppp6c	Rat	17alpha-ethynylestradiol	increases expression	ISO	Ppp6c (Mus musculus)	6480464	Ethinyl Estradiol results in increased expression of PPP6C mRNA	CTD	PMID:17942748
Ppp6c	Rat	17alpha-ethynylestradiol	multiple interactions	ISO	Ppp6c (Mus musculus)	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPP6C mRNA	CTD	PMID:17942748
Ppp6c	Rat	2,2',4,4'-Tetrabromodiphenyl ether	decreases expression	ISO	PPP6C (Homo sapiens)	6480464	2 more ...	CTD	PMID:31675489
Ppp6c	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	Ppp6c (Mus musculus)	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPP6C mRNA	CTD	PMID:17942748
Ppp6c	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Ppp6c (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of PPP6C mRNA	CTD	PMID:21570461
Ppp6c	Rat	2,6-dinitrotoluene	affects expression	EXP		6480464	2 and 6-dinitrotoluene affects the expression of PPP6C mRNA	CTD	PMID:21346803
Ppp6c	Rat	3,3',5,5'-tetrabromobisphenol A	decreases expression	ISO	PPP6C (Homo sapiens)	6480464	tetrabromobisphenol A results in decreased expression of PPP6C protein	CTD	PMID:31675489
Ppp6c	Rat	3H-1,2-dithiole-3-thione	decreases expression	EXP		6480464	1 and 2-dithiol-3-thione results in decreased expression of PPP6C mRNA	CTD	PMID:19162173
Ppp6c	Rat	4,4'-diaminodiphenylmethane	increases expression	ISO	Ppp6c (Mus musculus)	6480464	4 and 4'-diaminodiphenylmethane results in increased expression of PPP6C mRNA	CTD	PMID:18648102
Ppp6c	Rat	aflatoxin B1	decreases methylation	ISO	PPP6C (Homo sapiens)	6480464	Aflatoxin B1 results in decreased methylation of PPP6C gene	CTD	PMID:27153756
Ppp6c	Rat	ammonium chloride	affects expression	EXP		6480464	Ammonium Chloride affects the expression of PPP6C mRNA	CTD	PMID:16483693
Ppp6c	Rat	arsenite(3-)	multiple interactions	ISO	PPP6C (Homo sapiens)	6480464	arsenite promotes the reaction [G3BP1 protein binds to PPP6C mRNA]	CTD	PMID:32406909
Ppp6c	Rat	arsenous acid	increases expression	ISO	PPP6C (Homo sapiens)	6480464	Arsenic Trioxide results in increased expression of PPP6C mRNA	CTD	PMID:20458559
Ppp6c	Rat	benzo[a]pyrene	increases expression	ISO	Ppp6c (Mus musculus)	6480464	Benzo(a)pyrene results in increased expression of PPP6C mRNA	CTD	PMID:22228805
Ppp6c	Rat	benzo[a]pyrene	affects methylation	ISO	PPP6C (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of PPP6C intron	CTD	PMID:30157460
Ppp6c	Rat	benzo[a]pyrene	increases methylation	ISO	PPP6C (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of PPP6C promoter	CTD	PMID:27901495
Ppp6c	Rat	benzo[a]pyrene diol epoxide I	decreases expression	ISO	PPP6C (Homo sapiens)	6480464	7 more ...	CTD	PMID:19150397
Ppp6c	Rat	benzo[e]pyrene	increases methylation	ISO	PPP6C (Homo sapiens)	6480464	benzo(e)pyrene results in increased methylation of PPP6C intron	CTD	PMID:30157460
Ppp6c	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of PPP6C mRNA	CTD	PMID:33296240
Ppp6c	Rat	bisphenol A	decreases expression	ISO	PPP6C (Homo sapiens)	6480464	bisphenol A results in decreased expression of PPP6C protein	CTD	PMID:31675489
Ppp6c	Rat	Bisphenol B	increases expression	ISO	PPP6C (Homo sapiens)	6480464	bisphenol B results in increased expression of PPP6C protein	CTD	PMID:34186270
Ppp6c	Rat	butanal	decreases expression	ISO	PPP6C (Homo sapiens)	6480464	butyraldehyde results in decreased expression of PPP6C mRNA	CTD	PMID:26079696
Ppp6c	Rat	cadmium dichloride	increases expression	ISO	PPP6C (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of PPP6C mRNA	CTD	PMID:26472689
Ppp6c	Rat	chloropicrin	increases expression	ISO	PPP6C (Homo sapiens)	6480464	chloropicrin results in increased expression of PPP6C mRNA	CTD	PMID:26352163
Ppp6c	Rat	cocaine	affects expression	EXP		6480464	Cocaine affects the expression of PPP6C mRNA	CTD	PMID:20187946
Ppp6c	Rat	copper(II) sulfate	increases expression	ISO	PPP6C (Homo sapiens)	6480464	Copper Sulfate results in increased expression of PPP6C mRNA	CTD	PMID:19549813
Ppp6c	Rat	diarsenic trioxide	increases expression	ISO	PPP6C (Homo sapiens)	6480464	Arsenic Trioxide results in increased expression of PPP6C mRNA	CTD	PMID:20458559
Ppp6c	Rat	disodium selenite	increases expression	ISO	PPP6C (Homo sapiens)	6480464	Sodium Selenite results in increased expression of PPP6C mRNA	CTD	PMID:18175754
Ppp6c	Rat	flutamide	increases expression	EXP		6480464	Flutamide results in increased expression of PPP6C mRNA	CTD	PMID:24136188
Ppp6c	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of PPP6C mRNA	CTD	PMID:22061828
Ppp6c	Rat	ivermectin	decreases expression	ISO	PPP6C (Homo sapiens)	6480464	Ivermectin results in decreased expression of PPP6C protein	CTD	PMID:32959892
Ppp6c	Rat	lead(0)	affects splicing	ISO	PPP6C (Homo sapiens)	6480464	Lead affects the splicing of PPP6C mRNA	CTD	PMID:28903495
Ppp6c	Rat	methapyrilene	increases methylation	ISO	PPP6C (Homo sapiens)	6480464	Methapyrilene results in increased methylation of PPP6C intron	CTD	PMID:30157460
Ppp6c	Rat	methidathion	decreases expression	ISO	Ppp6c (Mus musculus)	6480464	methidathion results in decreased expression of PPP6C mRNA	CTD	PMID:34813904
Ppp6c	Rat	nefazodone	increases expression	EXP		6480464	nefazodone results in increased expression of PPP6C mRNA	CTD	PMID:24136188
Ppp6c	Rat	rotenone	increases expression	EXP		6480464	Rotenone results in increased expression of PPP6C protein	CTD	PMID:35544339
Ppp6c	Rat	sodium arsenite	increases expression	ISO	PPP6C (Homo sapiens)	6480464	sodium arsenite results in increased expression of PPP6C mRNA	CTD	PMID:38568856
Ppp6c	Rat	triptonide	increases expression	ISO	Ppp6c (Mus musculus)	6480464	triptonide results in increased expression of PPP6C mRNA	CTD	PMID:33045310
Ppp6c	Rat	valproic acid	affects expression	ISO	PPP6C (Homo sapiens)	6480464	Valproic Acid affects the expression of PPP6C mRNA	CTD	PMID:25979313
Ppp6c	Rat	valproic acid	decreases expression	ISO	PPP6C (Homo sapiens)	6480464	Valproic Acid results in decreased expression of PPP6C mRNA	CTD	PMID:37505509

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ppp6c	Rat	G1/S transition of mitotic cell cycle	involved_in	IBA	FB:FBgn0003139 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ppp6c	Rat	immune system process	involved_in	IEA	UniProtKB-KW:KW-0391	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ppp6c	Rat	innate immune response	involved_in	IEA	UniProtKB-KW:KW-0399	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ppp6c	Rat	negative regulation of cGAS/STING signaling pathway	involved_in	ISO	PPP6C (Homo sapiens)	1624291	PMID:32474700	RGD	PMID:32474700
Ppp6c	Rat	negative regulation of cGAS/STING signaling pathway	involved_in	IEA	UniProtKB:O00743 and ensembl:ENSP00000362648	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ppp6c	Rat	protein dephosphorylation		IMP		68293		RGD
Ppp6c	Rat	protein dephosphorylation	acts_upstream_of_or_within	ISO	PPP6C (Homo sapiens)	1624291	PMID:16716191	RGD	PMID:16716191

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ppp6c	Rat	cytoplasm	is_active_in	IBA	FB:FBgn0003139 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ppp6c	Rat	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Ppp6c	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ppp6c	Rat	cytosol	located_in	ISO	PPP6C (Homo sapiens)	1624291	PMID:16716191	RGD	PMID:16716191
Ppp6c	Rat	cytosol	located_in	IEA	UniProtKB:O00743 and ensembl:ENSP00000362648	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ppp6c	Rat	mitochondrion	located_in	IEA	UniProtKB-SubCell:SL-0173	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Ppp6c	Rat	mitochondrion	located_in	IEA	UniProtKB-KW:KW-0496	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ppp6c	Rat	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ppp6c	Rat	hydrolase activity	enables	IEA	InterPro:IPR004843 and InterPro:IPR006186	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Ppp6c	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ppp6c	Rat	phosphoprotein phosphatase activity	enables	IEA	UniProtKB-KW:KW-0904	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ppp6c	Rat	protein binding	enables	ISO	PPP6C (Homo sapiens)	1624291	UniProtKB:O15084 more ...	RGD	PMID:16085932 more ...
Ppp6c	Rat	protein serine/threonine phosphatase activity		IMP		68293		RGD
Ppp6c	Rat	protein serine/threonine phosphatase activity	enables	IEA	UniProtKB:Q9CQR6 and ensembl:ENSMUSP00000028087	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ppp6c	Rat	protein serine/threonine phosphatase activity	enables	IEA	RHEA:20629 and RHEA:47004	1600115	GO_REF:0000116	RHEA	GO_REF:0000116
Ppp6c	Rat	protein serine/threonine phosphatase activity	enables	ISO	Ppp6c (Mus musculus)	1624291	PMID:32474700	RGD	PMID:32474700
Ppp6c	Rat	protein serine/threonine phosphatase activity	enables	IBA	CGD:CAL0000187173 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ppp6c	Rat	protein serine/threonine phosphatase activity	enables	IEA	UniProtKB:O00743 and ensembl:ENSP00000362648	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ppp6c	Rat	protein serine/threonine phosphatase activity	enables	IEA	InterPro:IPR047129	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Ppp6c	Rat	protein serine/threonine phosphatase activity	enables	IEA	EC:3.1.3.16	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Ppp6c	Rat	protein serine/threonine phosphatase activity	enables	ISO	PPP6C (Homo sapiens)	1624291	PMID:16716191 and PMID:32474700	RGD	PMID:16716191 and PMID:32474700

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ppp6c	Rat	ataxia telangiectasia-mutated (ATM) signaling pathway		ISO	PPP6C (Homo sapiens)	8661242		RGD

#	Reference Title	Reference Citation
1.	Molecular cloning of a protein serine/threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain.	Becker W, etal., J Biol Chem 1994 Sep 9;269(36):22586-92.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Push back to respond better: regulatory inhibition of the DNA double-strand break response.	Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation
9.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

PMID:16716191	PMID:29476059	PMID:31505169

Ppp6c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	43,339,521 - 43,371,807 (-)	NCBI		GRCr8
mRatBN7.2	3	22,929,816 - 22,962,123 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	22,931,577 - 22,962,113 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	26,399,878 - 26,430,642 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	34,984,867 - 35,015,633 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	32,797,655 - 32,828,524 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	23,478,123 - 23,510,959 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	23,480,266 - 23,510,959 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	28,702,120 - 28,732,821 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	18,966,289 - 18,997,796 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	18,862,668 - 18,894,168 (-)	NCBI
Celera	3	21,363,667 - 21,394,395 (-)	NCBI		Celera
Cytogenetic Map	3	q12	NCBI

PPP6C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	125,146,573 - 125,189,803 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	125,146,573 - 125,189,939 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	127,908,852 - 127,952,082 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	126,951,228 - 126,991,886 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	124,990,962 - 125,031,619	NCBI
Celera	9	98,556,786 - 98,600,152 (-)	NCBI		Celera
Cytogenetic Map	9	q33.3	NCBI
HuRef	9	97,520,985 - 97,564,821 (-)	NCBI		HuRef
CHM1_1	9	128,057,572 - 128,101,275 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	137,344,915 - 137,388,140 (-)	NCBI		T2T-CHM13v2.0

Ppp6c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	39,084,381 - 39,116,361 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	39,084,366 - 39,116,463 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	39,194,369 - 39,226,349 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	39,194,354 - 39,226,451 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	39,052,318 - 39,081,858 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	39,018,807 - 39,048,348 (-)	NCBI		MGSCv36	mm8
Celera	2	40,922,991 - 40,952,523 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	24.44	NCBI

Ppp6c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	3,096,240 - 3,134,215 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	3,096,882 - 3,133,590 (+)	NCBI	ChiLan1.0	ChiLan1.0

PPP6C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	14,167,709 - 14,210,999 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	14,170,154 - 14,213,902 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	96,267,918 - 96,311,159 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	124,783,166 - 124,825,877 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	124,783,173 - 124,825,877 (-)	Ensembl	panpan1.1		panPan2

PPP6C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	57,884,035 - 57,921,080 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	43,094,942 - 43,095,395 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1 Ensembl	9	57,884,062 - 57,918,629 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	57,083,817 - 57,121,501 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	58,804,291 - 58,842,060 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	58,804,382 - 58,841,491 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	57,562,943 - 57,601,308 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	57,879,503 - 57,917,826 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	57,970,444 - 58,008,141 (+)	NCBI		UU_Cfam_GSD_1.0

Ppp6c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	193,515,568 - 193,552,293 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	13,283,931 - 13,321,526 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	13,284,652 - 13,320,936 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPP6C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	265,870,477 - 265,898,124 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	265,872,961 - 265,898,146 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	299,702,674 - 299,727,172 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPP6C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	12,964,706 - 13,007,339 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	12,964,842 - 13,007,351 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666079	3,096,731 - 3,144,887 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppp6c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	10,024,575 - 10,074,329 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	10,025,102 - 10,073,164 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Ppp6c
102 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	548
Count of miRNA genes:	240
Interacting mature miRNAs:	291
Transcripts:	ENSRNOT00000021176
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	8658162	27494778	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	body weight (CMO:0000012)	3	17374703	35528639	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	8227194	47233430	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	8227194	33703538	Rat
8693641	Alc30	Alcohol consumption QTL 30	2	0.739	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	3	10434306	24512004	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	15005422	76927699	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	39874793	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	pulse pressure (CMO:0000292)	3	1	33278763	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	1	33230976	Rat
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	36847613	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	18311454	47233430	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	18311454	47233430	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	18311454	47233430	Rat
10450804	Scl70	Serum cholesterol level QTL 70	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	20714090	65714090	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	10778823	30356773	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	18311454	47233430	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	10778704	50302886	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	18311454	47233430	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	18311454	47233430	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	18311454	47233430	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2325840	Bp345	Blood pressure QTL 345		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	18311454	28441896	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	16954708	61954708	Rat
10450794	Scl69	Serum cholesterol level QTL 69	6.3	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	20714090	65714090	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	1	31158234	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	8658162	27494778	Rat
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	1	27494778	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	38710544	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat

RH130670

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	22,937,178 - 22,937,375 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	23,486,023 - 23,486,219	NCBI	Rnor6.0
Rnor_5.0	3	28,707,885 - 28,708,081	UniSTS	Rnor5.0
RGSC_v3.4	3	18,972,054 - 18,972,250	UniSTS	RGSC3.4
Celera	3	21,369,432 - 21,369,628	UniSTS
RH 3.4 Map	3	268.7	UniSTS
Cytogenetic Map	3	q11	UniSTS

UniSTS:234385

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	22,931,000 - 22,931,156 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	23,479,847 - 23,480,002	NCBI	Rnor6.0
Rnor_5.0	3	28,701,709 - 28,701,864	UniSTS	Rnor5.0
RGSC_v3.4	3	18,965,878 - 18,966,033	UniSTS	RGSC3.4
Celera	3	21,363,256 - 21,363,411	UniSTS
Cytogenetic Map	3	q11	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_133589	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC063151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X77236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021176 ⟹ ENSRNOP00000021176

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	22,931,811 - 22,962,113 (-)	Ensembl
Rnor_6.0 Ensembl	3	23,480,266 - 23,510,959 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102106 ⟹ ENSRNOP00000094628

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	22,931,577 - 22,962,065 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110141 ⟹ ENSRNOP00000076929

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	22,931,577 - 22,962,065 (-)	Ensembl

RefSeq Acc Id:

NM_133589 ⟹ NP_598273

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	43,341,100 - 43,371,807 (-)	NCBI
mRatBN7.2	3	22,931,412 - 22,962,123 (-)	NCBI
Rnor_6.0	3	23,480,258 - 23,510,959 (-)	NCBI
Rnor_5.0	3	28,702,120 - 28,732,821 (-)	NCBI
RGSC_v3.4	3	18,966,289 - 18,997,796 (-)	RGD
Celera	3	21,363,667 - 21,394,395 (-)	RGD

Sequence:

show sequence

CGGACGTGACGTAAGGAGGGTTCCGGCTTCGGCCTCCGCCGCTGCCTCCGCTACTACCACCGCCGCCGCTGCTGTTGCCGCGGCTTGTTCTTCCTAAAATGGCGCCACTGGATCTGGACAAGTATGTG
GAGATAGCGCGGCAGTGCAAGTACCTTCCCGAAAACGACCTGAAGCGGCTATGTGACTATGTTTGTGATCTGCTCTTGGAAGAGTCGAATGTTCAGCCTGTATCAACGCCAGTAACAGTGTGCGGGGA
CATACATGGACAGTTTTATGATCTTTGCGAACTGTTCAGAACTGGAGGTCAGGTTCCTGACACAAACTACATATTTATGGGTGATTTTGTAGACAGAGGTTACTATAGTTTGGAGACCTTCACTTATC
TTCTTGCACTAAAGGCTAAGTGGCCTGACCGTATTACACTTTTAAGAGGAAATCATGAGAGTAGACAGATAACGCAGGTGTACGGATTTTATGATGAGTGCCAAACCAAATATGGAAATGCTAATGCC
TGGAGATACTGTACCAAAGTTTTTGACATGCTCACAGTAGCAGCTTTAATAGATGAGCAGATTTTGTGTGTTCATGGTGGTTTATCTCCTGATATCAAAACACTGGATCAAATTCGAACTATTGAGCG
AAATCAGGAAATTCCTCACAAAGGAGCATTTTGTGACCTGGTATGGTCAGATCCTGAAGATGTGGACACTTGGGCAATCAGTCCCAGAGGAGCAGGTTGGCTTTTTGGAGCAAAAGTCACAAATGAGT
TTGTTCATATCAACAACTTAAAACTCATCTGCAGAGCACATCAGCTTGTGCACGAAGGCTATAAGTTTATGTTTGACGAGAAGCTGGTCACAGTGTGGTCTGCTCCTAACTACTGCTATCGCTGTGGA
AACATTGCTTCCATCATGGTCTTCAAAGACGTCAACACGAGAGAACCAAAGTTATTCCGAGCAGTTCCAGATTCAGAACGTGTTATTCCTCCCAGAACCACGACGCCGTATTTCCTTTGAGGCCTTTG
CCATCCCGCTGGCCACTTTTTGCCCTCTTTTACCCCAACTTTCTTGTACCCTCTACAATATACTTTTTATTGAGCACTTTGCTGCTGAAATGCTGCCTCTTGCCTTTTTTTTTAATTTTAAATTATCT
AACTTTATTGTTTGTTATGGTGTCAATAGCAGTGTTTTTCTATCAGTTTTGTCACTCATCCTATCCCCACATGGACTCGTTTGAGAAGACTTGAGAAATGTCTTAATACTCACATTGCTGCATGTAGC
TCTTGCTTGTTTGCTGTTCTGGGGAGACAGGAAGCATCTCTTTTTTAAAAAGCCAATTGACAATTACATGGAAATCCTCCTCATTTGTATCAGCTAGCCTTTTGTTTTTGTTTGGTAGGATTTAAGAA
ATTTCAGCAGCAAAGTTGTCCAGTGGGCAGGATGGACTGCATATGCCTGAGTCATGTACCCTTGTCCAAGCTGTAAACTCCACTGTCCTTTGTTGGATGATAATTTGATGTTTTAAAAGGGTATAAAA
TAAATTGGTCTAAAGGGCTGCCCTCCTTGTTGTGTTTTTAAATTTTAGTTAAAAACTGCTACAGCTATGACTTTGTACATTAAGATAATTGTACTGATCTTTTTTCAAAAATCTTGTATTTTTTAATA
AAATAATCTTAAAACCCAGATAGGTTAAGTGTTAGAAATTTTAAAAAATTTACATTGTTAGCTGAAAGTTACTTTTTCTTTCTTATGTTTTCTTATTTTTTTTTTCTTTTTCTTTGTTGAGTTTTTGA
CCCTTTGGTTGAGTTAAAAATTTCAATTAAAATTCAATATTTTTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017591448 ⟹ XP_017446937

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	43,339,521 - 43,371,562 (-)	NCBI
mRatBN7.2	3	22,929,816 - 22,961,875 (-)	NCBI
Rnor_6.0	3	23,478,123 - 23,510,763 (-)	NCBI

Sequence:

show sequence

AGCTTGCGAGGCAAGCCCCTTCCGGCTGTGGGGCTCCCGCCGGCCCGCCCTTCTCCCTCGGCGGGATCCCTACCGTGCGCCCGATCCTGGCGCGACGGAGGGCGCTCAGTGGTGTGAGAGGACCGGGT
CCGACGCGGCGTGGCGCGGAGAACCAGGGGAACCCGAATTCCCCGAATGCTGTCCAGTTCTCTGAGGGGAGATCCCGGGAATGTCACGATCCCCTGGTCCCTACGGGACTCCGAGCTTAAAGACTCAT
TCTAACTCGCTCGGTCTCCCGGAGACGGAGCCCGGCGGAGAGGGTAGTGCTCCCGGGATGGGGTCCTCCCTGCAGAGTTAACAGGAGCTGCTGTCTGCTCCAGGGACACGGCCGCAGTGTGTTTTAAG
TCCCTGAAAGCGGCTATGTGACTATGTTTGTGATCTGCTCTTGGAAGAGTCGAATGTTCAGCCTGTATCAACGCCAGTAACAGTGTGCGGGGACATACATGGACAGTTTTATGATCTTTGCGAACTGT
TCAGAACTGGAGGTCAGGTTCCTGACACAAACTACATATTTATGGGTGATTTTGTAGACAGAGGTTACTATAGTTTGGAGACCTTCACTTATCTTCTTGCACTAAAGGCTAAGTGGCCTGACCGTATT
ACACTTTTAAGAGGAAATCATGAGAGTAGACAGATAACGCAGGTGTACGGATTTTATGATGAGTGCCAAACCAAATATGGAAATGCTAATGCCTGGAGATACTGTACCAAAGTTTTTGACATGCTCAC
AGTAGCAGCTTTAATAGATGAGCAGATTTTGTGTGTTCATGGTGGTTTATCTCCTGATATCAAAACACTGGATCAAATTCGAACTATTGAGCGAAATCAGGAAATTCCTCACAAAGGAGCATTTTGTG
ACCTGGTATGGTCAGATCCTGAAGATGTGGACACTTGGGCAATCAGTCCCAGAGGAGCAGGTTGGCTTTTTGGAGCAAAAGTCACAAATGAGTTTGTTCATATCAACAACTTAAAACTCATCTGCAGA
GCACATCAGCTTGTGCACGAAGGCTATAAGTTTATGTTTGACGAGAAGCTGGTCACAGTGTGGTCTGCTCCTAACTACTGCTATCGCTGTGGAAACATTGCTTCCATCATGGTCTTCAAAGACGTCAA
CACGAGAGAACCAAAGTTATTCCGAGCAGTTCCAGATTCAGAACGTGTTATTCCTCCCAGAACCACGACGCCGTATTTCCTTTGAGGCCTTTGCCATCCCGCTGGCCACTTTTTGCCCTCTTTTACCC
CAACTTTCTTGTACCCTCTACAATATACTTTTTATTGAGCACTTTGCTGCTGAAATGCTGCCTCTTGCCTTTTTTTTTAATTTTAAATTATCTAACTTTATTGTTTGTTATGGTGTCAATAGCAGTGT
TTTTCTATCAGTTTTGTCACTCATCCTATCCCCACATGGACTCGTTTGAGAAGACTTGAGAAATGTCTTAATACTCACATTGCTGCATGTAGCTCTTGCTTGTTTGCTGTTCTGGGGAGACAGGAAGC
ATCTCTTTTTTAAAAAGCCAATTGACAATTACATGGAAATCCTCCTCATTTGTATCAGCTAGCCTTTTGTTTTTGTTTGGTAGGATTTAAGAAATTTCAGCAGCAAAGTTGTCCAGTGGGCAGGATGG
ACTGCATATGCCTGAGTCATGTACCCTTGTCCAAGCTGTAAACTCCACTGTCCTTTGTTGGATGATAATTTGATGTTTTAAAAGGGTATAAAATAAATTGGTCTAAAGGGCTGCCCTCCTTGTTGTGT
TTTTAAATTTTAGTTAAAAACTGCTACAGCTATGACTTTGTACATTAAGATAATTGTACTGATCTTTTTTCAAAAATCTTGTATTTTTTAATAAAATAATCTTAAAACCCAGATAGGTTAAGTGTTAG
AAATTTTAAAAAATTTACATTGTTAGCTGAAAGTTACTTTTTCTTTCTTATGTTTTCTTATTTTTTTTTTCTTTTTCTTTGTTGAGTTTTTGACCCTTTGGTTGAGTTAAAAATTTCAATTAAAATTC
AATATTTTTTTAAAAAAAATCACTAAATTGTGCCTAAAGAACATAACTGCCATATTAATGTTTTTATTTCTATAGTATTAGAAAACATTTAATACTTATAGCATTAATGTGTTGATTTGATACCAATT
GAGTAGAATGTGCTCAGTCCAGTTTACACTCTGTCATGAGTATCATCAAGTAAACACATGTACTTTTCAATAGCAAGCATTCTCTCGCTGTAACCTTTGACCTTAACTTTTACAAAGTATTCAGTTTT
TAACTGCAATTTTAAAGGCTGAACAATCAGAACCCTTGTGTTTGTGAACTGTAATCTGAAGCAGATTAAAGTATGAGAAAAAACAGACTGTTCCCTTGTGAAGGTCTGTCATACCATATTTCAGCTTT
GTGCTTATAATTTGACTATCTAAAGGGTTGTGATGATCAGTTCTTGATATATAATTGTCCACTTAATAAGGACATGTATATTATCATTATCTCTTATGACTGTAGTCATAGATAATTTGGGGATGTAC
CATCTTATGAAATTGTTGGTATCCCTTTATAATTTCTCGTCATCCCAGGAAATCCATGTGAAGGCTGATTGATAAAGCACTTTAGCATCTGTTCAGGTAGTTTTAAAAACAACTTTTCCCCTTCAGGA
TAAGAGCTTCCGGGTTATCTAAAAATGCAATAAAGATCTTAATAGTCTAAGCTTCTTGGCAAATAATCTTTCATCAGGGTTTCTTTTACTGAATGAGCACAATGTTATTTTGATTTTATTTGTCCCAA
AGCACCCAGCTCCTTGTACAGTTTTTAATGGTGTGGCTCTATGAAAGAAGCGGCTGAGACATTTGATGCACACACTTGAACCAATAGTGGATCAGTAGCTTTGTGTGTGTCTCCTAACCCCGGTGTAA
TTCGGGTGGAAAGGTATTTTATCTCACAGGAATATGTAGCTATGTATTTTACTAATTGTGAAACACTGGAATTAATGATGCAGATAACTTGGTGTGGTTTTTGAACAGCTCTGCAGTATTTTCTTGTT
GTTACCATAAATTGTATTTAAGTGCTTGCCCTCCACTGCTTTTAAGTTGTACCAGTAAAACCAGTAACTCTCAATCAATCCCCTTTCCACTTCGCACTCCCTAGCTTAGTTGGTACAGTTGTTTTCAT
TCTCCTTGTAATGTGACTTATTTTCAAGTCATGGTGCACTGCATTTGTTTGTCACTAGCTGGGCATGTGCCAATAATACTCTGTCCATTCCTTAACTGCCATCTCTGTTTTGCCTGAGTTTTCTTCTA
CTGATAATGGCTTTGGGGCATGGAAAAAGTAGTTTTTGCTATTAGACTTGTGAAGGAAAGAGAGAGTGAATGTATCGGACTTTGTAAGCCTGAAAACGAATATTTGGATCCCTCTACTAAACAAGGGC
TATGTACTATACAGAGTAATCTTGTGGTGGGAGATGCTTGCAAGCCAGAGGTCTGTAGGCGAGGGAATCTGCCTCTCCCTGTATCTAGGCCGAATGTAAAACCCCTTATGTTGTATCAATGGAGCTAA
GAACTATTTTTATTTGCCTGTGATATATTTCGTTTCTAATAAAGTGTTCTAGGCTCCAGTGAGAACTGTCTACTTTGAATTGCCATCTCCTCCCTTTCTTCATTTGGCTGATAGACTCCTGGCTAGCT
GTCCATAGATCAATGCTTCTCCCTAAAGCATCCTCGTTTCTTTAAATGTGTTCACTCGTGCGTGATCCTAAAAGCCTTGACTACATCTATTATGCAACCTGGACCAGCTCCTGTTCCACCTGGATGTC
TAGAGCTGTTGGGAGATTTTGACATCTTAAATGCTGACTTTTGCTTTTGAAATAAGGTTCAAAATGTTTGTTGCATTTAAGATCTGTGTGTGTGCGTGTGTTTGCTCTGTAACCCCAGCTCCAGGTGT
TGGAAAATGCCTGTACTGTGAAAGCCTGCCGCTGTCAGAAGTAGAAGCACTTTTGTCAGCTTCCAGAAAATTATGTACAGAGTTGGAGAGATTTAACTACAAGATTTATCTCTAAGAATCCAAATTTT
TAAATGTCATTGTTTTTTAAATGCTAATGTTTGTAAAGCACCTTCAGTTCTTTCAATGAAAGGTGCTACATTCCCTCGGTGTCAATTAATAAAAAGATTATAGGAA

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Protein RefSeqs	NP_598273	(Get FASTA)	NCBI Sequence Viewer
	XP_017446937	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78747	(Get FASTA)	NCBI Sequence Viewer
	CAA54453	(Get FASTA)	NCBI Sequence Viewer
	EDM00494	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021176
	ENSRNOP00000094628.1
GenBank Protein	Q64620	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_598273 ⟸ NM_133589

- UniProtKB:

Q6AZ47 (UniProtKB/Swiss-Prot), Q64620 (UniProtKB/Swiss-Prot), A6JEW6 (UniProtKB/TrEMBL), A0A8L2QAN5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAPLDLDKYVEIARQCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDE
CQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVW
SAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL

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RefSeq Acc Id:

XP_017446937 ⟸ XM_017591448

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYC
TKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIAS
IMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL

hide sequence

Ensembl Acc Id:

ENSRNOP00000021176 ⟸ ENSRNOT00000021176

Ensembl Acc Id:

ENSRNOP00000094628 ⟸ ENSRNOT00000102106

Ensembl Acc Id:

ENSRNOP00000076929 ⟸ ENSRNOT00000110141

Protein Domains

Serine/threonine specific protein phosphatases

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q64620-F1-model_v2	AlphaFold	Q64620	1-305	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13692060

Promoter ID:

EPDNEW_R2584

Type:

multiple initiation site

Name:

Ppp6c_1

Description:

protein phosphatase 6, catalytic subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	23,510,935 - 23,510,995	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-49880	BioCyc
Ensembl Genes	ENSRNOG00000015145	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000021176	ENTREZGENE
	ENSRNOT00000102106.1	UniProtKB/Swiss-Prot
Gene3D-CATH	3.60.21.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7131278	IMAGE-MGC_LOAD
InterPro	Calcineurin-like_PHP_ApaH	UniProtKB/Swiss-Prot
	Metallo-depent_PP-like	UniProtKB/Swiss-Prot
	PPA2-like	UniProtKB/Swiss-Prot
	Ser/Thr-sp_prot-phosphatase	UniProtKB/Swiss-Prot
KEGG Report	rno:171121	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93213	IMAGE-MGC_LOAD
NCBI Gene	171121	ENTREZGENE
PANTHER	SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED	UniProtKB/Swiss-Prot
Pfam	Metallophos	UniProtKB/Swiss-Prot
PhenoGen	Ppp6c	PhenoGen
PRINTS	STPHPHTASE	UniProtKB/Swiss-Prot
PROSITE	SER_THR_PHOSPHATASE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000015145	RatGTEx
SMART	PP2Ac	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF56300	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZK68_RAT	UniProtKB/TrEMBL
	A0A8L2QAN5	ENTREZGENE, UniProtKB/TrEMBL
	A6JEW6	ENTREZGENE, UniProtKB/TrEMBL
	PPP6_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6AZ47	ENTREZGENE
UniProt Secondary	Q6AZ47	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-11-17	Ppp6c	protein phosphatase 6, catalytic subunit		protein phosphatase V	Name updated	1299863	APPROVED
2004-09-10	Ppp6c	protein phosphatase V	LOC171121		Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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