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Gene: Ppp6c (protein phosphatase 6, catalytic subunit) Rattus norvegicus

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Symbol:

Ppp6c

Name:

protein phosphatase 6, catalytic subunit

RGD ID:

708460

Description:

Enables protein serine/threonine phosphatase activity. Predicted to be involved in G1/S transition of mitotic cell cycle and negative regulation of cGAS/STING signaling pathway. Predicted to act upstream of or within cGAS/STING signaling pathway. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human PPP6C (protein phosphatase 6 catalytic subunit); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione; ammonium chloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC171121; MGC93213; PP-V; PP6C; protein phosphatase V; serine/threonine-protein phosphatase 6 catalytic subunit

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PPP6C (protein phosphatase 6 catalytic subunit)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ppp6c (protein phosphatase 6, catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ppp6c (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PPP6C (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PPP6C (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ppp6c (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PPP6C (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PPP6C (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ppp6c (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ppp6c (protein phosphatase 6 catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TAF3 (TATA-box binding protein associated factor 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PPP6C (protein phosphatase 6 catalytic subunit)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ppp6c (protein phosphatase 6, catalytic subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ppp6c (protein phosphatase 6, catalytic subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pph-6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pph-6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	PpV	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SIT4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ppp6c	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	43,339,521 - 43,371,807 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	43,341,108 - 43,371,807 (-)	Ensembl				GRCr8
mRatBN7.2	3	22,929,816 - 22,962,123 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	22,931,577 - 22,962,113 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	26,399,878 - 26,430,642 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	34,984,867 - 35,015,633 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	32,797,655 - 32,828,524 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	23,478,123 - 23,510,959 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	23,480,266 - 23,510,959 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	28,702,120 - 28,732,821 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	18,966,289 - 18,997,796 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	21,363,667 - 21,394,395 (-)	NCBI		Celera
RGSC_v3.1	3	18,862,668 - 18,894,168 (-)	NCBI
Cytogenetic Map	3	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

basal cell carcinoma (ISO)

melanoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (ISO)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

chloropicrin (ISO)

cocaine (EXP)

copper(II) sulfate (ISO)

diarsenic trioxide (ISO)

disodium selenite (ISO)

flutamide (EXP)

gentamycin (EXP)

ivermectin (ISO)

lead(0) (ISO)

methapyrilene (ISO)

methidathion (ISO)

nefazodone (EXP)

rotenone (EXP)

sodium arsenite (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G1/S transition of mitotic cell cycle (IBA)

immune system process (IEA)

innate immune response (IEA)

negative regulation of cGAS/STING signaling pathway (IEA,ISO)

protein dephosphorylation (IMP,ISO)

Cellular Component

cytoplasm (IBA,IEA)

cytosol (IEA,ISO)

mitochondrion (IEA)

Molecular Function

hydrolase activity (IEA)

metal ion binding (IEA)

phosphoprotein phosphatase activity (IEA)

protein binding (ISO)

protein serine/threonine phosphatase activity (IBA,IEA,IMP,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ataxia telangiectasia-mutated (ATM) signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Molecular cloning of a protein serine/threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain.	Becker W, etal., J Biol Chem 1994 Sep 9;269(36):22586-92.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Push back to respond better: regulatory inhibition of the DNA double-strand break response.	Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation
9.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:16716191	PMID:29476059	PMID:31505169

Genomics

Comparative Map Data

Ppp6c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	43,339,521 - 43,371,807 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	43,341,108 - 43,371,807 (-)	Ensembl				GRCr8
mRatBN7.2	3	22,929,816 - 22,962,123 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	22,931,577 - 22,962,113 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	26,399,878 - 26,430,642 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	34,984,867 - 35,015,633 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	32,797,655 - 32,828,524 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	23,478,123 - 23,510,959 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	23,480,266 - 23,510,959 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	28,702,120 - 28,732,821 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	18,966,289 - 18,997,796 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	21,363,667 - 21,394,395 (-)	NCBI		Celera
RGSC_v3.1	3	18,862,668 - 18,894,168 (-)	NCBI
Cytogenetic Map	3	q12	NCBI

PPP6C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	125,146,573 - 125,189,803 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	125,146,573 - 125,189,939 (-)	Ensembl			hg38	GRCh38
GRCh37	9	127,908,852 - 127,952,082 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	126,951,228 - 126,991,886 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	124,990,962 - 125,031,619	NCBI
Celera	9	98,556,786 - 98,600,152 (-)	NCBI		Celera
Cytogenetic Map	9	q33.3	NCBI
HuRef	9	97,520,985 - 97,564,821 (-)	NCBI		HuRef
CHM1_1	9	128,057,572 - 128,101,275 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	137,344,915 - 137,388,140 (-)	NCBI		T2T-CHM13v2.0

Ppp6c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	39,084,381 - 39,116,361 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	39,084,366 - 39,116,463 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	39,194,369 - 39,226,349 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	39,194,354 - 39,226,451 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	39,052,318 - 39,081,858 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	39,018,807 - 39,048,348 (-)	NCBI		MGSCv36	mm8
Celera	2	40,922,991 - 40,952,523 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	24.44	NCBI

Ppp6c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	3,096,240 - 3,134,215 (+)	Ensembl
ChiLan1.0	NW_004955419	3,096,882 - 3,133,590 (+)	NCBI	ChiLan1.0	ChiLan1.0

PPP6C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	14,167,709 - 14,210,999 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	14,170,154 - 14,213,902 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	96,267,918 - 96,311,159 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	124,783,166 - 124,825,877 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	124,783,173 - 124,825,877 (-)	Ensembl			panPan2	panpan1.1

PPP6C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	57,884,035 - 57,921,080 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	43,094,942 - 43,095,395 (+)	Ensembl			canFam3	CanFam3.1
CanFam3.1 Ensembl	9	57,884,062 - 57,918,629 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	57,083,817 - 57,121,501 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	58,804,291 - 58,842,060 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	58,804,382 - 58,841,491 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	57,562,943 - 57,601,308 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	57,879,503 - 57,917,826 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	57,970,444 - 58,008,141 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ppp6c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	193,515,568 - 193,552,293 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	13,283,931 - 13,321,526 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	13,284,652 - 13,320,936 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPP6C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	265,870,477 - 265,898,124 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	265,872,961 - 265,898,146 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	299,702,674 - 299,727,172 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPP6C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	12,964,706 - 13,007,339 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	12,964,842 - 13,007,351 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666079	3,096,731 - 3,144,887 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppp6c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	10,024,575 - 10,074,329 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624760	10,025,102 - 10,073,164 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ppp6c
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	16,918,633 - 16,951,031 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ppp6c
295 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	548
Count of miRNA genes:	240
Interacting mature miRNAs:	291
Transcripts:	ENSRNOT00000021176
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	29056275	47904329	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	body weight (CMO:0000012)	3	37772258	55937853	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	28625339	67641995	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	35403199	97383526	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	6125437	51125437	Rat
8693641	Alc30	Alcohol consumption QTL 30	2	0.739	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	3	30832384	44921701	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	15272348	60272348	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	36425116	81425116	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	37796919	53640235	Rat
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	37796919	82796919	Rat
10450811	Scl73	Serum cholesterol level QTL 73	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
2292615	Ept17	Estrogen-induced pituitary tumorigenesis QTL 17	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat
10450808	Scl72	Serum cholesterol level QTL 72	4.4	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	38708931	67641995	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
10450806	Scl71	Serum cholesterol level QTL 71	5.8	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	38708931	67641995	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	38708931	67641995	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	36721849	110333156	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	38708931	67641995	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	38708931	67641995	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	38708931	67641995	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	38708931	67641995	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	42158111	124558371	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
2325840	Bp345	Blood pressure QTL 345		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	38708931	83708931	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	37363734	82363734	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	6556347	51556347	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	36101403	81101403	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	42158111	124558371	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	29056275	47904329	Rat
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	37796919	47904329	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	37796919	59119581	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358185	Ept6	Estrogen-induced pituitary tumorigenesis QTL 6	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat

Markers in Region

RH130670

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	22,937,178 - 22,937,375 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	23,486,023 - 23,486,219	NCBI	Rnor6.0
Rnor_5.0	3	28,707,885 - 28,708,081	UniSTS	Rnor5.0
RGSC_v3.4	3	18,972,054 - 18,972,250	UniSTS	RGSC3.4
Celera	3	21,369,432 - 21,369,628	UniSTS
RH 3.4 Map	3	268.7	UniSTS
Cytogenetic Map	3	q11	UniSTS

UniSTS:234385

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	22,931,000 - 22,931,156 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	23,479,847 - 23,480,002	NCBI	Rnor6.0
Rnor_5.0	3	28,701,709 - 28,701,864	UniSTS	Rnor5.0
RGSC_v3.4	3	18,965,878 - 18,966,033	UniSTS	RGSC3.4
Celera	3	21,363,256 - 21,363,411	UniSTS
Cytogenetic Map	3	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133589	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC063151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X77236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021176 ⟹ ENSRNOP00000021176

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	43,341,108 - 43,371,807 (-)	Ensembl
mRatBN7.2 Ensembl	3	22,931,811 - 22,962,113 (-)	Ensembl
Rnor_6.0 Ensembl	3	23,480,266 - 23,510,959 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102106 ⟹ ENSRNOP00000094628

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	43,341,108 - 43,356,065 (-)	Ensembl
mRatBN7.2 Ensembl	3	22,931,577 - 22,962,065 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110141 ⟹ ENSRNOP00000076929

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	43,341,108 - 43,371,807 (-)	Ensembl
mRatBN7.2 Ensembl	3	22,931,577 - 22,962,065 (-)	Ensembl

RefSeq Acc Id:

NM_133589 ⟹ NP_598273

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	43,341,100 - 43,371,807 (-)	NCBI
mRatBN7.2	3	22,931,412 - 22,962,123 (-)	NCBI
Rnor_6.0	3	23,480,258 - 23,510,959 (-)	NCBI
Rnor_5.0	3	28,702,120 - 28,732,821 (-)	NCBI
RGSC_v3.4	3	18,966,289 - 18,997,796 (-)	RGD
Celera	3	21,363,667 - 21,394,395 (-)	RGD

Sequence:

show sequence

CGGACGTGACGTAAGGAGGGTTCCGGCTTCGGCCTCCGCCGCTGCCTCCGCTACTACCACCGCC
GCCGCTGCTGTTGCCGCGGCTTGTTCTTCCTAAAATGGCGCCACTGGATCTGGACAAGTATGTG
GAGATAGCGCGGCAGTGCAAGTACCTTCCCGAAAACGACCTGAAGCGGCTATGTGACTATGTTT
GTGATCTGCTCTTGGAAGAGTCGAATGTTCAGCCTGTATCAACGCCAGTAACAGTGTGCGGGGA
CATACATGGACAGTTTTATGATCTTTGCGAACTGTTCAGAACTGGAGGTCAGGTTCCTGACACA
AACTACATATTTATGGGTGATTTTGTAGACAGAGGTTACTATAGTTTGGAGACCTTCACTTATC
TTCTTGCACTAAAGGCTAAGTGGCCTGACCGTATTACACTTTTAAGAGGAAATCATGAGAGTAG
ACAGATAACGCAGGTGTACGGATTTTATGATGAGTGCCAAACCAAATATGGAAATGCTAATGCC
TGGAGATACTGTACCAAAGTTTTTGACATGCTCACAGTAGCAGCTTTAATAGATGAGCAGATTT
TGTGTGTTCATGGTGGTTTATCTCCTGATATCAAAACACTGGATCAAATTCGAACTATTGAGCG
AAATCAGGAAATTCCTCACAAAGGAGCATTTTGTGACCTGGTATGGTCAGATCCTGAAGATGTG
GACACTTGGGCAATCAGTCCCAGAGGAGCAGGTTGGCTTTTTGGAGCAAAAGTCACAAATGAGT
TTGTTCATATCAACAACTTAAAACTCATCTGCAGAGCACATCAGCTTGTGCACGAAGGCTATAA
GTTTATGTTTGACGAGAAGCTGGTCACAGTGTGGTCTGCTCCTAACTACTGCTATCGCTGTGGA
AACATTGCTTCCATCATGGTCTTCAAAGACGTCAACACGAGAGAACCAAAGTTATTCCGAGCAG
TTCCAGATTCAGAACGTGTTATTCCTCCCAGAACCACGACGCCGTATTTCCTTTGAGGCCTTTG
CCATCCCGCTGGCCACTTTTTGCCCTCTTTTACCCCAACTTTCTTGTACCCTCTACAATATACT
TTTTATTGAGCACTTTGCTGCTGAAATGCTGCCTCTTGCCTTTTTTTTTAATTTTAAATTATCT
AACTTTATTGTTTGTTATGGTGTCAATAGCAGTGTTTTTCTATCAGTTTTGTCACTCATCCTAT
CCCCACATGGACTCGTTTGAGAAGACTTGAGAAATGTCTTAATACTCACATTGCTGCATGTAGC
TCTTGCTTGTTTGCTGTTCTGGGGAGACAGGAAGCATCTCTTTTTTAAAAAGCCAATTGACAAT
TACATGGAAATCCTCCTCATTTGTATCAGCTAGCCTTTTGTTTTTGTTTGGTAGGATTTAAGAA
ATTTCAGCAGCAAAGTTGTCCAGTGGGCAGGATGGACTGCATATGCCTGAGTCATGTACCCTTG
TCCAAGCTGTAAACTCCACTGTCCTTTGTTGGATGATAATTTGATGTTTTAAAAGGGTATAAAA
TAAATTGGTCTAAAGGGCTGCCCTCCTTGTTGTGTTTTTAAATTTTAGTTAAAAACTGCTACAG
CTATGACTTTGTACATTAAGATAATTGTACTGATCTTTTTTCAAAAATCTTGTATTTTTTAATA
AAATAATCTTAAAACCCAGATAGGTTAAGTGTTAGAAATTTTAAAAAATTTACATTGTTAGCTG
AAAGTTACTTTTTCTTTCTTATGTTTTCTTATTTTTTTTTTCTTTTTCTTTGTTGAGTTTTTGA
CCCTTTGGTTGAGTTAAAAATTTCAATTAAAATTCAATATTTTTTTAAAAAAAAAAAAAAAAAA
AAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017591448 ⟹ XP_017446937

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	43,339,521 - 43,371,562 (-)	NCBI
mRatBN7.2	3	22,929,816 - 22,961,875 (-)	NCBI
Rnor_6.0	3	23,478,123 - 23,510,763 (-)	NCBI

Sequence:

show sequence

AGCTTGCGAGGCAAGCCCCTTCCGGCTGTGGGGCTCCCGCCGGCCCGCCCTTCTCCCTCGGCGG
GATCCCTACCGTGCGCCCGATCCTGGCGCGACGGAGGGCGCTCAGTGGTGTGAGAGGACCGGGT
CCGACGCGGCGTGGCGCGGAGAACCAGGGGAACCCGAATTCCCCGAATGCTGTCCAGTTCTCTG
AGGGGAGATCCCGGGAATGTCACGATCCCCTGGTCCCTACGGGACTCCGAGCTTAAAGACTCAT
TCTAACTCGCTCGGTCTCCCGGAGACGGAGCCCGGCGGAGAGGGTAGTGCTCCCGGGATGGGGT
CCTCCCTGCAGAGTTAACAGGAGCTGCTGTCTGCTCCAGGGACACGGCCGCAGTGTGTTTTAAG
TCCCTGAAAGCGGCTATGTGACTATGTTTGTGATCTGCTCTTGGAAGAGTCGAATGTTCAGCCT
GTATCAACGCCAGTAACAGTGTGCGGGGACATACATGGACAGTTTTATGATCTTTGCGAACTGT
TCAGAACTGGAGGTCAGGTTCCTGACACAAACTACATATTTATGGGTGATTTTGTAGACAGAGG
TTACTATAGTTTGGAGACCTTCACTTATCTTCTTGCACTAAAGGCTAAGTGGCCTGACCGTATT
ACACTTTTAAGAGGAAATCATGAGAGTAGACAGATAACGCAGGTGTACGGATTTTATGATGAGT
GCCAAACCAAATATGGAAATGCTAATGCCTGGAGATACTGTACCAAAGTTTTTGACATGCTCAC
AGTAGCAGCTTTAATAGATGAGCAGATTTTGTGTGTTCATGGTGGTTTATCTCCTGATATCAAA
ACACTGGATCAAATTCGAACTATTGAGCGAAATCAGGAAATTCCTCACAAAGGAGCATTTTGTG
ACCTGGTATGGTCAGATCCTGAAGATGTGGACACTTGGGCAATCAGTCCCAGAGGAGCAGGTTG
GCTTTTTGGAGCAAAAGTCACAAATGAGTTTGTTCATATCAACAACTTAAAACTCATCTGCAGA
GCACATCAGCTTGTGCACGAAGGCTATAAGTTTATGTTTGACGAGAAGCTGGTCACAGTGTGGT
CTGCTCCTAACTACTGCTATCGCTGTGGAAACATTGCTTCCATCATGGTCTTCAAAGACGTCAA
CACGAGAGAACCAAAGTTATTCCGAGCAGTTCCAGATTCAGAACGTGTTATTCCTCCCAGAACC
ACGACGCCGTATTTCCTTTGAGGCCTTTGCCATCCCGCTGGCCACTTTTTGCCCTCTTTTACCC
CAACTTTCTTGTACCCTCTACAATATACTTTTTATTGAGCACTTTGCTGCTGAAATGCTGCCTC
TTGCCTTTTTTTTTAATTTTAAATTATCTAACTTTATTGTTTGTTATGGTGTCAATAGCAGTGT
TTTTCTATCAGTTTTGTCACTCATCCTATCCCCACATGGACTCGTTTGAGAAGACTTGAGAAAT
GTCTTAATACTCACATTGCTGCATGTAGCTCTTGCTTGTTTGCTGTTCTGGGGAGACAGGAAGC
ATCTCTTTTTTAAAAAGCCAATTGACAATTACATGGAAATCCTCCTCATTTGTATCAGCTAGCC
TTTTGTTTTTGTTTGGTAGGATTTAAGAAATTTCAGCAGCAAAGTTGTCCAGTGGGCAGGATGG
ACTGCATATGCCTGAGTCATGTACCCTTGTCCAAGCTGTAAACTCCACTGTCCTTTGTTGGATG
ATAATTTGATGTTTTAAAAGGGTATAAAATAAATTGGTCTAAAGGGCTGCCCTCCTTGTTGTGT
TTTTAAATTTTAGTTAAAAACTGCTACAGCTATGACTTTGTACATTAAGATAATTGTACTGATC
TTTTTTCAAAAATCTTGTATTTTTTAATAAAATAATCTTAAAACCCAGATAGGTTAAGTGTTAG
AAATTTTAAAAAATTTACATTGTTAGCTGAAAGTTACTTTTTCTTTCTTATGTTTTCTTATTTT
TTTTTTCTTTTTCTTTGTTGAGTTTTTGACCCTTTGGTTGAGTTAAAAATTTCAATTAAAATTC
AATATTTTTTTAAAAAAAATCACTAAATTGTGCCTAAAGAACATAACTGCCATATTAATGTTTT
TATTTCTATAGTATTAGAAAACATTTAATACTTATAGCATTAATGTGTTGATTTGATACCAATT
GAGTAGAATGTGCTCAGTCCAGTTTACACTCTGTCATGAGTATCATCAAGTAAACACATGTACT
TTTCAATAGCAAGCATTCTCTCGCTGTAACCTTTGACCTTAACTTTTACAAAGTATTCAGTTTT
TAACTGCAATTTTAAAGGCTGAACAATCAGAACCCTTGTGTTTGTGAACTGTAATCTGAAGCAG
ATTAAAGTATGAGAAAAAACAGACTGTTCCCTTGTGAAGGTCTGTCATACCATATTTCAGCTTT
GTGCTTATAATTTGACTATCTAAAGGGTTGTGATGATCAGTTCTTGATATATAATTGTCCACTT
AATAAGGACATGTATATTATCATTATCTCTTATGACTGTAGTCATAGATAATTTGGGGATGTAC
CATCTTATGAAATTGTTGGTATCCCTTTATAATTTCTCGTCATCCCAGGAAATCCATGTGAAGG
CTGATTGATAAAGCACTTTAGCATCTGTTCAGGTAGTTTTAAAAACAACTTTTCCCCTTCAGGA
TAAGAGCTTCCGGGTTATCTAAAAATGCAATAAAGATCTTAATAGTCTAAGCTTCTTGGCAAAT
AATCTTTCATCAGGGTTTCTTTTACTGAATGAGCACAATGTTATTTTGATTTTATTTGTCCCAA
AGCACCCAGCTCCTTGTACAGTTTTTAATGGTGTGGCTCTATGAAAGAAGCGGCTGAGACATTT
GATGCACACACTTGAACCAATAGTGGATCAGTAGCTTTGTGTGTGTCTCCTAACCCCGGTGTAA
TTCGGGTGGAAAGGTATTTTATCTCACAGGAATATGTAGCTATGTATTTTACTAATTGTGAAAC
ACTGGAATTAATGATGCAGATAACTTGGTGTGGTTTTTGAACAGCTCTGCAGTATTTTCTTGTT
GTTACCATAAATTGTATTTAAGTGCTTGCCCTCCACTGCTTTTAAGTTGTACCAGTAAAACCAG
TAACTCTCAATCAATCCCCTTTCCACTTCGCACTCCCTAGCTTAGTTGGTACAGTTGTTTTCAT
TCTCCTTGTAATGTGACTTATTTTCAAGTCATGGTGCACTGCATTTGTTTGTCACTAGCTGGGC
ATGTGCCAATAATACTCTGTCCATTCCTTAACTGCCATCTCTGTTTTGCCTGAGTTTTCTTCTA
CTGATAATGGCTTTGGGGCATGGAAAAAGTAGTTTTTGCTATTAGACTTGTGAAGGAAAGAGAG
AGTGAATGTATCGGACTTTGTAAGCCTGAAAACGAATATTTGGATCCCTCTACTAAACAAGGGC
TATGTACTATACAGAGTAATCTTGTGGTGGGAGATGCTTGCAAGCCAGAGGTCTGTAGGCGAGG
GAATCTGCCTCTCCCTGTATCTAGGCCGAATGTAAAACCCCTTATGTTGTATCAATGGAGCTAA
GAACTATTTTTATTTGCCTGTGATATATTTCGTTTCTAATAAAGTGTTCTAGGCTCCAGTGAGA
ACTGTCTACTTTGAATTGCCATCTCCTCCCTTTCTTCATTTGGCTGATAGACTCCTGGCTAGCT
GTCCATAGATCAATGCTTCTCCCTAAAGCATCCTCGTTTCTTTAAATGTGTTCACTCGTGCGTG
ATCCTAAAAGCCTTGACTACATCTATTATGCAACCTGGACCAGCTCCTGTTCCACCTGGATGTC
TAGAGCTGTTGGGAGATTTTGACATCTTAAATGCTGACTTTTGCTTTTGAAATAAGGTTCAAAA
TGTTTGTTGCATTTAAGATCTGTGTGTGTGCGTGTGTTTGCTCTGTAACCCCAGCTCCAGGTGT
TGGAAAATGCCTGTACTGTGAAAGCCTGCCGCTGTCAGAAGTAGAAGCACTTTTGTCAGCTTCC
AGAAAATTATGTACAGAGTTGGAGAGATTTAACTACAAGATTTATCTCTAAGAATCCAAATTTT
TAAATGTCATTGTTTTTTAAATGCTAATGTTTGTAAAGCACCTTCAGTTCTTTCAATGAAAGGT
GCTACATTCCCTCGGTGTCAATTAATAAAAAGATTATAGGAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_598273	(Get FASTA)	NCBI Sequence Viewer
	XP_017446937	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78747	(Get FASTA)	NCBI Sequence Viewer
	CAA54453	(Get FASTA)	NCBI Sequence Viewer
	EDM00494	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021176
	ENSRNOP00000094628.1
GenBank Protein	Q64620	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_598273 ⟸ NM_133589

- UniProtKB:

Q6AZ47 (UniProtKB/Swiss-Prot), Q64620 (UniProtKB/Swiss-Prot), A6JEW6 (UniProtKB/TrEMBL), A0A8L2QAN5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAPLDLDKYVEIARQCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCEL
FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDE
CQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFC
DLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVW
SAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL

hide sequence

RefSeq Acc Id:

XP_017446937 ⟸ XM_017591448

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYC
TKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWA
ISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIAS
IMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL

hide sequence

Ensembl Acc Id:

ENSRNOP00000021176 ⟸ ENSRNOT00000021176

Ensembl Acc Id:

ENSRNOP00000094628 ⟸ ENSRNOT00000102106

Ensembl Acc Id:

ENSRNOP00000076929 ⟸ ENSRNOT00000110141

Protein Domains

Serine/threonine specific protein phosphatases

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q64620-F1-model_v2	AlphaFold	Q64620	1-305	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692060

Promoter ID:

EPDNEW_R2584

Type:

multiple initiation site

Name:

Ppp6c_1

Description:

protein phosphatase 6, catalytic subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	23,510,935 - 23,510,995	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708460	AgrOrtholog
BioCyc Gene	G2FUF-49880	BioCyc
Ensembl Genes	ENSRNOG00000015145	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000021176	ENTREZGENE
	ENSRNOT00000102106.1	UniProtKB/Swiss-Prot
Gene3D-CATH	3.60.21.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7131278	IMAGE-MGC_LOAD
InterPro	Calcineurin-like_PHP_ApaH	UniProtKB/Swiss-Prot
	Metallo-depent_PP-like	UniProtKB/Swiss-Prot
	PPA2-like	UniProtKB/Swiss-Prot
	Ser/Thr-sp_prot-phosphatase	UniProtKB/Swiss-Prot
KEGG Report	rno:171121	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93213	IMAGE-MGC_LOAD
NCBI Gene	171121	ENTREZGENE
PANTHER	SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED	UniProtKB/Swiss-Prot
Pfam	Metallophos	UniProtKB/Swiss-Prot
PhenoGen	Ppp6c	PhenoGen
PRINTS	STPHPHTASE	UniProtKB/Swiss-Prot
PROSITE	SER_THR_PHOSPHATASE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000015145	RatGTEx
SMART	PP2Ac	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF56300	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZK68_RAT	UniProtKB/TrEMBL
	A0A8L2QAN5	ENTREZGENE, UniProtKB/TrEMBL
	A6JEW6	ENTREZGENE, UniProtKB/TrEMBL
	PPP6_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6AZ47	ENTREZGENE
UniProt Secondary	Q6AZ47	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-11-17	Ppp6c	protein phosphatase 6, catalytic subunit		protein phosphatase V	Name updated	1299863	APPROVED
2004-09-10	Ppp6c	protein phosphatase V	LOC171121		Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

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Imported Disease Annotations - CTD

RGD Manual Annotations