Symbol:
Pex5l
Name:
peroxisomal biogenesis factor 5-like
RGD ID:
708407
Description:
Enables intracellularly cyclic nucleotide-activated monoatomic cation channel activity and small GTPase binding activity. Involved in positive regulation of corticotropin secretion and regulated exocytosis. Located in cell tip and perinuclear region of cytoplasm. Part of intracellular cyclic nucleotide activated cation channel complex. Orthologous to human PEX5L (peroxisomal biogenesis factor 5 like); INTERACTS WITH 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil; acrylamide.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
peroxin 2; peroxin-5-related protein; Pex2; PEX5-like protein; PEX5-related protein; pex5Rp; tetratricopeptide repeat-containing Rab8b-interacting protein; TPR-containing Rab8b-interacting protein; TRIP8b; Trjip8b
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 117,623,199 - 117,836,772 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 2 117,623,199 - 117,836,685 (-) Ensembl GRCr8 mRatBN7.2 2 115,694,868 - 115,908,365 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 115,700,972 - 115,913,628 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 2 122,300,502 - 122,514,052 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 120,413,149 - 120,626,695 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 115,115,247 - 115,325,579 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 119,330,330 - 119,405,809 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 119,330,080 - 119,537,837 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 2 138,979,958 - 139,053,451 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 2 119,130,798 - 119,203,567 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 2 110,803,018 - 110,875,273 (-) NCBI Celera RGSC_v3.1 2 119,075,759 - 119,284,697 (-) NCBI Cytogenetic Map 2 q24 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Pex5l Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Pex5l (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pex5l Rat 1,2-dichloroethane decreases expression ISO Pex5l (Mus musculus) 6480464 ethylene dichloride results in decreased expression of PEX5L mRNA CTD PMID:28960355 Pex5l Rat 1,2-dimethylhydrazine increases expression ISO Pex5l (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of PEX5L mRNA CTD PMID:22206623 Pex5l Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Pex5l (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pex5l Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Pex5l (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pex5l Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Pex5l (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pex5l Rat 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of PEX5L mRNA CTD PMID:30071829 Pex5l Rat 4,4'-sulfonyldiphenol decreases methylation ISO Pex5l (Mus musculus) 6480464 bisphenol S results in decreased methylation of PEX5L exon CTD PMID:33297965 Pex5l Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of PEX5L mRNA CTD PMID:24780913 Pex5l Rat acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of PEX5L mRNA CTD PMID:28959563 Pex5l Rat acrylamide increases expression ISO PEX5L (Homo sapiens) 6480464 Acrylamide results in increased expression of PEX5L mRNA CTD PMID:32763439 Pex5l Rat aflatoxin B1 decreases methylation ISO PEX5L (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of PEX5L gene CTD PMID:27153756 Pex5l Rat all-trans-retinoic acid multiple interactions ISO Pex5l (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PEX5L mRNA CTD PMID:36189433 Pex5l Rat all-trans-retinoic acid decreases expression ISO Pex5l (Mus musculus) 6480464 Tretinoin results in decreased expression of PEX5L mRNA CTD PMID:36189433 Pex5l Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PEX5L mRNA CTD PMID:16483693 Pex5l Rat aristolochic acid A increases expression ISO PEX5L (Homo sapiens) 6480464 aristolochic acid I results in increased expression of PEX5L mRNA CTD PMID:33212167 Pex5l Rat arsenite(3-) multiple interactions ISO PEX5L (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to PEX5L mRNA] CTD PMID:32406909 Pex5l Rat benzo[a]pyrene increases methylation ISO PEX5L (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of PEX5L promoter CTD PMID:27901495 Pex5l Rat benzo[a]pyrene increases expression ISO PEX5L (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of PEX5L mRNA CTD PMID:32234424 Pex5l Rat bis(2-ethylhexyl) phthalate decreases expression ISO PEX5L (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of PEX5L mRNA CTD PMID:31163220 Pex5l Rat bis(2-ethylhexyl) phthalate decreases expression ISO Pex5l (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of PEX5L mRNA CTD PMID:34319233 Pex5l Rat bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of PEX5L mRNA CTD PMID:33789034 Pex5l Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Pex5l (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... CTD PMID:39150890 Pex5l Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PEX5L mRNA CTD PMID:25181051|PMID:30816183|PMID:32528016|PMID:34947998 Pex5l Rat bisphenol A decreases expression ISO Pex5l (Mus musculus) 6480464 bisphenol A results in decreased expression of PEX5L mRNA CTD PMID:32156529 Pex5l Rat bisphenol A multiple interactions ISO PEX5L (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PEX5L gene CTD PMID:31601247 Pex5l Rat Butylbenzyl phthalate multiple interactions ISO Pex5l (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... CTD PMID:39150890 Pex5l Rat Butylbenzyl phthalate increases methylation ISO Pex5l (Mus musculus) 6480464 butylbenzyl phthalate results in increased methylation of PEX5L intron CTD PMID:28392331 Pex5l Rat cocaine increases expression EXP 6480464 Cocaine results in increased expression of PEX5L mRNA CTD PMID:17898221 Pex5l Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of PEX5L mRNA CTD PMID:26577399 Pex5l Rat dibutyl phthalate multiple interactions ISO Pex5l (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... CTD PMID:39150890 Pex5l Rat dichloroacetic acid decreases expression ISO Pex5l (Mus musculus) 6480464 Dichloroacetic Acid results in decreased expression of PEX5L mRNA CTD PMID:28962523 Pex5l Rat diethyl phthalate multiple interactions ISO Pex5l (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... CTD PMID:39150890 Pex5l Rat diisobutyl phthalate multiple interactions ISO Pex5l (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... CTD PMID:39150890 Pex5l Rat diisononyl phthalate multiple interactions ISO Pex5l (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... CTD PMID:39150890 Pex5l Rat dimethylarsinic acid increases methylation EXP 6480464 Cacodylic Acid results in increased methylation of PEX5L gene CTD PMID:37958445 Pex5l Rat entinostat decreases expression ISO PEX5L (Homo sapiens) 6480464 entinostat results in decreased expression of PEX5L mRNA CTD PMID:27188386 Pex5l Rat ethanol increases expression ISO Pex5l (Mus musculus) 6480464 Ethanol results in increased expression of PEX5L mRNA CTD PMID:19167417 Pex5l Rat ethanol affects splicing ISO Pex5l (Mus musculus) 6480464 Ethanol affects the splicing of PEX5L mRNA CTD PMID:30319688 Pex5l Rat formaldehyde decreases expression ISO PEX5L (Homo sapiens) 6480464 Formaldehyde results in decreased expression of PEX5L mRNA CTD PMID:23649840 Pex5l Rat fulvestrant decreases methylation ISO PEX5L (Homo sapiens) 6480464 Fulvestrant results in decreased methylation of PEX5L gene CTD PMID:31601247 Pex5l Rat fulvestrant multiple interactions ISO PEX5L (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PEX5L gene CTD PMID:31601247 Pex5l Rat glyphosate affects methylation EXP 6480464 Glyphosate affects the methylation of PEX5L gene CTD PMID:35440735 Pex5l Rat kojic acid decreases expression ISO PEX5L (Homo sapiens) 6480464 kojic acid results in decreased expression of PEX5L mRNA CTD PMID:16595896 Pex5l Rat methyl methanesulfonate decreases expression ISO PEX5L (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of PEX5L mRNA CTD PMID:23649840 Pex5l Rat mono(2-ethylhexyl) phthalate multiple interactions ISO Pex5l (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PEX5L mRNA CTD PMID:36189433 Pex5l Rat okadaic acid decreases expression ISO PEX5L (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of PEX5L mRNA CTD PMID:38832940 Pex5l Rat PCB138 multiple interactions ISO Pex5l (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pex5l Rat resveratrol multiple interactions ISO PEX5L (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of PEX5L mRNA CTD PMID:23557933 Pex5l Rat Theaflavin 3,3'-digallate affects expression ISO PEX5L (Homo sapiens) 6480464 theaflavin-3,3'-digallate affects the expression of PEX5L mRNA CTD PMID:34925699 Pex5l Rat valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of PEX5L mRNA CTD PMID:29427782 Pex5l Rat valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of PEX5L mRNA CTD PMID:29427782