Clcn4 (chloride voltage-gated channel 4) - Rat Genome Database

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Gene: Clcn4 (chloride voltage-gated channel 4) Rattus norvegicus
Analyze
Symbol: Clcn4
Name: chloride voltage-gated channel 4
RGD ID: 708381
Description: Predicted to enable antiporter activity and voltage-gated chloride channel activity. Predicted to be involved in chloride transport and non-motile cilium assembly. Predicted to be located in endoplasmic reticulum membrane; endosome; and lysosomal membrane. Predicted to be active in several cellular components, including Golgi apparatus; ciliary base; and cytoplasmic vesicle. Human ortholog(s) of this gene implicated in Raynaud-Claes syndrome. Orthologous to human CLCN4 (chloride voltage-gated channel 4); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: chloride channel 4; chloride channel 4-2; chloride channel protein 4; chloride channel, voltage-sensitive 4; chloride transporter ClC-4; clC-4; Clcn4-2; h(+)/Cl(-) exchange transporter 4; MGC105433; putative chloride channel (similar to Mm Clcn4-2); putative chloride channel 4-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X27,290,769 - 27,356,967 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX27,290,868 - 27,356,939 (+)EnsemblGRCr8
mRatBN7.2X23,729,194 - 23,795,391 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX23,729,338 - 23,793,238 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX24,703,884 - 24,767,782 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X28,124,882 - 28,188,779 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X24,377,222 - 24,441,104 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X25,016,177 - 25,082,563 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX25,016,401 - 25,080,410 (+)Ensemblrn6Rnor6.0
Rnor_5.0X25,427,399 - 25,493,756 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X44,355,648 - 44,419,524 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX24,157,917 - 24,221,792 (+)NCBICelera
RGSC_v3.1X44,436,114 - 44,471,196 (+)NCBI
Cytogenetic MapXq13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP)
diquat  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethylbenzene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fonofos  (ISO)
furan  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
L-ethionine  (EXP)
lead(0)  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
Methylazoxymethanol acetate  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
omeprazole  (EXP)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
raloxifene  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
terbufos  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
toluene  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Properties of voltage-gated chloride channels of the ClC gene family. Jentsch TJ, etal., J Physiol 1995 Jan;482:19S-25S.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10564087   PMID:12477932   PMID:17023393   PMID:23647072   PMID:25644381   PMID:27550844   PMID:28972156  


Genomics

Comparative Map Data
Clcn4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X27,290,769 - 27,356,967 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX27,290,868 - 27,356,939 (+)EnsemblGRCr8
mRatBN7.2X23,729,194 - 23,795,391 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX23,729,338 - 23,793,238 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX24,703,884 - 24,767,782 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X28,124,882 - 28,188,779 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X24,377,222 - 24,441,104 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X25,016,177 - 25,082,563 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX25,016,401 - 25,080,410 (+)Ensemblrn6Rnor6.0
Rnor_5.0X25,427,399 - 25,493,756 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X44,355,648 - 44,419,524 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX24,157,917 - 24,221,792 (+)NCBICelera
RGSC_v3.1X44,436,114 - 44,471,196 (+)NCBI
Cytogenetic MapXq13NCBI
CLCN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X10,156,975 - 10,237,660 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX10,156,943 - 10,237,660 (+)Ensemblhg38GRCh38
GRCh37X10,125,015 - 10,205,700 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X10,084,985 - 10,165,700 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X9,934,772 - 10,013,256NCBI
CeleraX14,296,240 - 14,376,955 (+)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX7,954,825 - 8,038,622 (+)NCBIHuRef
CHM1_1X10,155,417 - 10,236,107 (+)NCBICHM1_1
T2T-CHM13v2.0X9,739,532 - 9,820,250 (+)NCBIT2T-CHM13v2.0
Clcn4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3977,285,308 - 7,303,837 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl77,285,308 - 7,303,850 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3877,282,309 - 7,300,916 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl77,282,309 - 7,300,851 (-)Ensemblmm10GRCm38
MGSCv3777,235,027 - 7,252,222 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3676,887,494 - 6,902,833 (-)NCBIMGSCv36mm8
MGSCv3676,634,944 - 6,651,482 (-)NCBIMGSCv36mm8
Cytogenetic Map7A1NCBI
cM Map74.23NCBI
Clcn4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555442,922,338 - 3,000,112 (-)Ensembl
ChiLan1.0NW_0049555442,922,338 - 2,999,979 (-)NCBIChiLan1.0ChiLan1.0
CLCN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X11,958,252 - 12,039,812 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X11,962,836 - 12,043,479 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X2,787,185 - 2,867,846 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X10,040,067 - 10,120,991 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX10,040,067 - 10,120,991 (+)EnsemblpanPan2panpan1.1
CLCN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X6,853,184 - 6,921,478 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX6,854,728 - 6,917,594 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX6,809,155 - 6,878,437 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X6,799,857 - 6,868,917 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX6,799,854 - 6,868,914 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X6,790,241 - 6,854,866 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X6,825,444 - 6,894,478 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X6,815,874 - 6,884,896 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Clcn4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X142,869 - 215,738 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936470142,832 - 212,154 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936470142,862 - 214,993 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLCN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX6,939,387 - 7,019,738 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X6,939,637 - 7,019,745 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X7,339,448 - 7,419,589 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CLCN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X8,611,443 - 8,692,944 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX8,611,485 - 8,693,192 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605610,305,321 - 10,386,398 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clcn4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248824,080,525 - 4,148,628 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248824,080,525 - 4,148,749 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Clcn4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X27,594,640 - 27,660,850 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Clcn4
347 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:630
Count of miRNA genes:304
Interacting mature miRNAs:398
Transcripts:ENSRNOT00000059270
Prediction methods:Microtar, Miranda, Pita, Pita,Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2447036044931007Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X400149344939387Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2447036045082063Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X197044046970440Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X811148653111486Rat

Markers in Region
DXGot9  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X23,759,526 - 23,759,772 (+)MAPPERmRatBN7.2
Rnor_6.0X25,046,703 - 25,046,948NCBIRnor6.0
Rnor_5.0X25,457,896 - 25,458,141UniSTSRnor5.0
RGSC_v3.4X44,385,815 - 44,386,058RGDRGSC3.4
RGSC_v3.4X44,385,816 - 44,386,061UniSTSRGSC3.4
CeleraX24,188,076 - 24,188,321UniSTS
RGSC_v3.1X44,439,284 - 44,439,527RGD
RH 2.0 Map21231.6RGD
Cytogenetic MapXq21UniSTS
RH142591  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X23,791,567 - 23,791,755 (+)MAPPERmRatBN7.2
Rnor_6.0X25,078,740 - 25,078,927NCBIRnor6.0
Rnor_5.0X25,489,933 - 25,490,120UniSTSRnor5.0
RGSC_v3.4X44,417,853 - 44,418,040UniSTSRGSC3.4
CeleraX24,220,121 - 24,220,308UniSTS
Cytogenetic MapXq21UniSTS
RH137747  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X23,793,009 - 23,793,131 (+)MAPPERmRatBN7.2
Rnor_6.0X25,080,182 - 25,080,303NCBIRnor6.0
Rnor_5.0X25,491,375 - 25,491,496UniSTSRnor5.0
RGSC_v3.4X44,419,295 - 44,419,416UniSTSRGSC3.4
CeleraX24,221,563 - 24,221,684UniSTS
Cytogenetic MapXq21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 91 59 6 355 191 11 144 81 89 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000059270   ⟹   ENSRNOP00000056037
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX27,290,868 - 27,355,242 (+)Ensembl
mRatBN7.2 EnsemblX23,729,338 - 23,793,238 (+)Ensembl
Rnor_6.0 EnsemblX25,016,401 - 25,080,410 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100086   ⟹   ENSRNOP00000080147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX27,290,868 - 27,355,242 (+)Ensembl
mRatBN7.2 EnsemblX23,729,338 - 23,793,238 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000130513   ⟹   ENSRNOP00000102441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX27,317,868 - 27,356,939 (+)Ensembl
RefSeq Acc Id: NM_022198   ⟹   NP_071534
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X27,290,939 - 27,354,815 (+)NCBI
mRatBN7.2X23,729,359 - 23,793,239 (+)NCBI
Rnor_6.0X25,016,401 - 25,080,411 (+)NCBI
Rnor_5.0X25,427,399 - 25,493,756 (+)NCBI
RGSC_v3.4X44,355,648 - 44,419,524 (+)RGD
CeleraX24,157,917 - 24,221,792 (+)RGD
Sequence:
RefSeq Acc Id: XM_006256828   ⟹   XP_006256890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X27,290,769 - 27,356,967 (+)NCBI
mRatBN7.2X23,729,194 - 23,795,391 (+)NCBI
Rnor_6.0X25,016,177 - 25,082,563 (+)NCBI
Rnor_5.0X25,427,399 - 25,493,756 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_071534 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256890 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH92209 (Get FASTA)   NCBI Sequence Viewer  
  CAA85406 (Get FASTA)   NCBI Sequence Viewer  
  EDL90594 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000056037
GenBank Protein P51794 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071534   ⟸   NM_022198
- UniProtKB: P51794 (UniProtKB/Swiss-Prot),   Q56A19 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256890   ⟸   XM_006256828
- Peptide Label: isoform X1
- UniProtKB: P51794 (UniProtKB/Swiss-Prot),   F7F9W4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000056037   ⟸   ENSRNOT00000059270
Ensembl Acc Id: ENSRNOP00000080147   ⟸   ENSRNOT00000100086
Ensembl Acc Id: ENSRNOP00000102441   ⟸   ENSRNOT00000130513
Protein Domains
CBS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P51794-F1-model_v2 AlphaFold P51794 1-747 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701778
Promoter ID:EPDNEW_R12302
Type:initiation region
Name:Clcn4_1
Description:chloride voltage-gated channel 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X25,016,378 - 25,016,438EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708381 AgrOrtholog
BioCyc Gene G2FUF-2685 BioCyc
Ensembl Genes ENSRNOG00000003533 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000059270 ENTREZGENE
Gene3D-CATH 3.10.580.20 UniProtKB/Swiss-Prot
  3.90.1280.20 UniProtKB/Swiss-Prot
  Clc chloride channel UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7315063 IMAGE-MGC_LOAD
InterPro CBS_dom UniProtKB/Swiss-Prot
  CBS_dom_sf UniProtKB/Swiss-Prot
  Cl-channel_core UniProtKB/Swiss-Prot
  Cl-channel_volt-gated UniProtKB/Swiss-Prot
  Cl_channel-4 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105433 IMAGE-MGC_LOAD
NCBI Gene 60586 ENTREZGENE
PANTHER CHLORIDE CHANNEL PROTEIN UniProtKB/Swiss-Prot
  PTHR45711:SF2 UniProtKB/Swiss-Prot
Pfam CBS UniProtKB/Swiss-Prot
  Voltage_CLC UniProtKB/Swiss-Prot
PhenoGen Clcn4 PhenoGen
PRINTS CLCHANNEL UniProtKB/Swiss-Prot
  CLCHANNEL4 UniProtKB/Swiss-Prot
PROSITE CBS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003533 RatGTEx
SMART CBS UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54631 UniProtKB/Swiss-Prot
  SSF81340 UniProtKB/Swiss-Prot
UniProt A0A8I5ZPI6_RAT UniProtKB/TrEMBL
  A0ABK0LGP4_RAT UniProtKB/TrEMBL
  CLCN4_RAT UniProtKB/Swiss-Prot
  F7F9W4 ENTREZGENE, UniProtKB/TrEMBL
  P51794 ENTREZGENE
  Q56A19 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Clcn4  chloride voltage-gated channel 4  Clcn4  chloride channel, voltage-sensitive 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-16 Clcn4  chloride channel, voltage-sensitive 4  Clcn4  chloride channel 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-10 Clcn4  chloride channel 4  Clcn4-2  chloride channel 4-2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Clcn4-2  chloride channel 4-2  Clcn4-2  putative chloride channel 4-2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Clcn4-2  putative chloride channel 4-2    putative chloride channel (similar to Mm Clcn4-2)  Name updated 1299863 APPROVED
2005-09-30 Clcn4-2        Symbol and Name status set to provisional 70820 PROVISIONAL