Ccdc80 (coiled-coil domain containing 80) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Ccdc80 (coiled-coil domain containing 80) Rattus norvegicus
Analyze
Symbol: Ccdc80
Name: coiled-coil domain containing 80
RGD ID: 69421
Description: Predicted to enable fibronectin binding activity and heparin binding activity. Predicted to be involved in extracellular matrix organization and positive regulation of cell-substrate adhesion. Predicted to act upstream of or within response to bacterium. Predicted to be located in interstitial matrix. Predicted to be active in basement membrane. Orthologous to human CCDC80 (coiled-coil domain containing 80); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CL2; coiled-coil domain-containing protein 80; down-regulated by oncogenes 1 protein; Dro1; SSG-1; Ssg1; steroid sensitive gene 1; steroid sensitive gene-1 protein; steroid-sensitive gene 1 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81169,191,188 - 69,224,844 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1169,191,189 - 69,224,844 (-)EnsemblGRCr8
mRatBN7.21155,685,165 - 55,718,827 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1155,685,872 - 55,719,137 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1164,498,843 - 64,532,488 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01157,160,702 - 57,194,361 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01156,230,920 - 56,264,579 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01160,645,660 - 60,679,249 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1160,645,086 - 60,679,555 (-)Ensemblrn6Rnor6.0
Rnor_5.01164,747,815 - 64,781,404 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41157,222,551 - 57,257,162 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1155,250,971 - 55,284,620 (-)NCBICelera
RGSC_v3.11157,280,642 - 57,314,846 (-)NCBI
Cytogenetic Map11q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
aristolochic acid A  (EXP,ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bilirubin IXalpha  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buspirone  (EXP)
butanal  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
CU-O LINKAGE  (ISO)
Didecyldimethylammonium  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
fipronil  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gentamycin  (EXP)
Indeno[1,2,3-cd]pyrene  (ISO)
inulin  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
levofloxacin  (EXP)
lipopolysaccharide  (ISO)
mifepristone  (EXP)
N-nitrosodiethylamine  (EXP)
naled  (ISO)
nefazodone  (EXP)
nickel sulfate  (ISO)
nimesulide  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cloning and characterization of a novel gene that is regulated by estrogen and is associated with mammary gland carcinogenesis. Marcantonio D, etal., Endocrinology 2001 Jun;142(6):2409-18.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:12592395   PMID:15489334   PMID:15563452   PMID:18757743   PMID:23012479   PMID:23449887   PMID:24006456  


Genomics

Comparative Map Data
Ccdc80
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81169,191,188 - 69,224,844 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1169,191,189 - 69,224,844 (-)EnsemblGRCr8
mRatBN7.21155,685,165 - 55,718,827 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1155,685,872 - 55,719,137 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1164,498,843 - 64,532,488 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01157,160,702 - 57,194,361 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01156,230,920 - 56,264,579 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01160,645,660 - 60,679,249 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1160,645,086 - 60,679,555 (-)Ensemblrn6Rnor6.0
Rnor_5.01164,747,815 - 64,781,404 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41157,222,551 - 57,257,162 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1155,250,971 - 55,284,620 (-)NCBICelera
RGSC_v3.11157,280,642 - 57,314,846 (-)NCBI
Cytogenetic Map11q21NCBI
CCDC80
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383112,596,797 - 112,641,143 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3112,596,797 - 112,649,530 (-)Ensemblhg38GRCh38
GRCh373112,315,644 - 112,359,990 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363113,806,097 - 113,842,667 (-)NCBIBuild 36Build 36hg18NCBI36
Build 343113,806,100 - 113,842,667NCBI
Celera3110,732,063 - 110,768,628 (-)NCBICelera
Cytogenetic Map3q13.2NCBI
HuRef3109,706,775 - 109,743,319 (-)NCBIHuRef
CHM1_13112,287,318 - 112,323,877 (-)NCBICHM1_1
T2T-CHM13v2.03115,317,839 - 115,362,183 (-)NCBIT2T-CHM13v2.0
Ccdc80
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391644,913,770 - 44,948,287 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1644,913,765 - 44,948,440 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381645,093,407 - 45,127,924 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1645,093,402 - 45,128,077 (+)Ensemblmm10GRCm38
MGSCv371645,094,166 - 45,128,037 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361645,013,496 - 45,046,996 (+)NCBIMGSCv36mm8
Celera1645,485,370 - 45,521,051 (+)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1629.39NCBI
Ccdc80
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542712,945,230 - 12,975,114 (-)Ensembl
ChiLan1.0NW_00495542712,945,230 - 12,975,020 (-)NCBIChiLan1.0ChiLan1.0
CCDC80
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22110,607,542 - 110,645,344 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13110,603,851 - 110,648,646 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03109,753,743 - 109,789,769 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13116,678,009 - 116,714,001 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3116,678,161 - 116,712,611 (-)EnsemblpanPan2panpan1.1
CCDC80
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13317,105,086 - 17,141,380 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3317,105,086 - 17,139,896 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3317,208,232 - 17,244,374 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03317,348,918 - 17,385,073 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3317,348,924 - 17,383,880 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13317,153,695 - 17,189,794 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03317,201,117 - 17,237,246 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03317,750,713 - 17,786,844 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ccdc80
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602137,191,030 - 137,227,449 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936536293,549 - 330,998 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936536294,650 - 330,875 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC80
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13147,207,598 - 147,245,994 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113147,203,333 - 147,244,753 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213156,787,502 - 156,825,938 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCDC80
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12268,168,159 - 68,182,818 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605087,161,904 - 87,198,049 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc80
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473135,891,184 - 35,929,936 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473135,891,180 - 35,928,497 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ccdc80
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1429,856,597 - 29,890,041 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ccdc80
336 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:101
Count of miRNA genes:82
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000059735
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 68 59 6 332 168 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000059735   ⟹   ENSRNOP00000056490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1169,191,189 - 69,224,844 (-)Ensembl
mRatBN7.2 Ensembl1155,685,872 - 55,719,137 (-)Ensembl
Rnor_6.0 Ensembl1160,645,086 - 60,679,555 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1160,646,402 - 60,650,293 (-)Ensembl
RefSeq Acc Id: NM_022543   ⟹   NP_071988
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81169,191,188 - 69,224,844 (-)NCBI
mRatBN7.21155,685,165 - 55,718,827 (-)NCBI
Rnor_6.01160,645,660 - 60,679,249 (-)NCBI
Rnor_5.01164,747,815 - 64,781,404 (-)NCBI
RGSC_v3.41157,222,551 - 57,257,162 (-)RGD
Celera1155,250,971 - 55,284,620 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_071988 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF35351 (Get FASTA)   NCBI Sequence Viewer  
  AAH70926 (Get FASTA)   NCBI Sequence Viewer  
  AAS66670 (Get FASTA)   NCBI Sequence Viewer  
  EDM11148 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000056490
  ENSRNOP00000056490.2
GenBank Protein Q6QD51 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071988   ⟸   NM_022543
- Peptide Label: precursor
- UniProtKB: Q6IRG8 (UniProtKB/Swiss-Prot),   Q9JKW4 (UniProtKB/Swiss-Prot),   Q6QD51 (UniProtKB/Swiss-Prot),   A6IQZ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000056490   ⟸   ENSRNOT00000059735
Protein Domains
DUF4174

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6QD51-F1-model_v2 AlphaFold Q6QD51 1-949 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698144
Promoter ID:EPDNEW_R8668
Type:multiple initiation site
Name:Ccdc80_1
Description:coiled-coil domain containing 80
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R8669  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01160,679,394 - 60,679,454EPDNEW
RGD ID:13698145
Promoter ID:EPDNEW_R8669
Type:multiple initiation site
Name:Ccdc80_2
Description:coiled-coil domain containing 80
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R8668  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01160,679,555 - 60,679,615EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69421 AgrOrtholog
BioCyc Gene G2FUF-21372 BioCyc
Ensembl Genes ENSRNOG00000002052 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000059735 ENTREZGENE
  ENSRNOT00000059735.4 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7096530 IMAGE-MGC_LOAD
InterPro DUF4174 UniProtKB/Swiss-Prot
KEGG Report rno:64387 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91686 IMAGE-MGC_LOAD
NCBI Gene 64387 ENTREZGENE
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 80 UniProtKB/Swiss-Prot
  COILED-COIL DOMAIN-CONTAINING PROTEIN 80 UniProtKB/Swiss-Prot
Pfam DUF4174 UniProtKB/Swiss-Prot
PhenoGen Ccdc80 PhenoGen
RatGTEx ENSRNOG00000002052 RatGTEx
TIGR TC205354
UniProt A6IQZ5 ENTREZGENE, UniProtKB/TrEMBL
  CCD80_RAT UniProtKB/Swiss-Prot
  Q6IRG8 ENTREZGENE
  Q6QD51 ENTREZGENE
  Q9JKW4 ENTREZGENE
UniProt Secondary Q6IRG8 UniProtKB/Swiss-Prot
  Q9JKW4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-18 Ccdc80  coiled-coil domain containing 80  Ssg1  steroid sensitive gene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Ssg1  steroid sensitive gene 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes to the cytoplasm and nucleus 1299213
gene_disease overexpression is correlated with mammary carcinogensis 68732
gene_expression protein expressed in uterus, liver, lung, spleen, kidney, heart, bladder, skeletal muscle, and brain 68732
gene_process may play a role in estrogen functions 68732
gene_protein 949 amino-acid protein 1299213
gene_regulation tightly regulated by 17 beta-estradiol (E2) in the normal mammary gland 68732