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Gene: Acsl6 (acyl-CoA synthetase long-chain family member 6) Rattus norvegicus

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Symbol:

Acsl6

Name:

acyl-CoA synthetase long-chain family member 6

RGD ID:

69403

Description:

Enables arachidonate-CoA ligase activity and protein homodimerization activity. Involved in several processes, including cellular response to insulin stimulus; lipid biosynthetic process; and positive regulation of long-chain fatty acid import across plasma membrane. Predicted to be located in endoplasmic reticulum membrane; mitochondrial outer membrane; and peroxisomal membrane. Predicted to be active in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia and leukemia. Orthologous to human ACSL6 (acyl-CoA synthetase long chain family member 6); PARTICIPATES IN fatty acid beta degradation pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; fatty acid metabolic pathway; INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

arachidonate--CoA ligase; Facl6; fatty acid Coenzyme A ligase, long chain 6; LACS 6; Lacsl; long-chain acyl-CoA synthetase 6; long-chain acyl-CoA synthetase-like; long-chain-fatty-acid--CoA ligase 6; long-chain-fatty-acid--CoA ligase, brain isozyme

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	38,940,668 - 38,999,515 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	38,940,747 - 39,002,873 (+)	Ensembl				GRCr8
mRatBN7.2	10	38,439,914 - 38,501,182 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	38,440,080 - 38,498,757 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	43,136,726 - 43,184,107 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	42,626,824 - 42,674,198 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	38,130,538 - 38,177,913 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	39,654,771 - 39,717,592 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	39,655,455 - 39,719,312 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	39,430,561 - 39,491,346 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	39,729,805 - 39,778,106 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	37,792,002 - 37,839,268 (+)	NCBI		Celera
RGSC_v3.1	10	39,743,427 - 39,791,726 (+)	NCBI
Cytogenetic Map	10	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

amphetamine abuse (ISO)

Experimental Diabetes Mellitus (IEP)

Hereditary Neoplastic Syndromes (ISO)

Inflammation (IEP)

leukemia (ISO)

myelodysplastic syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

(S)-nicotine (EXP,ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2-palmitoylglycerol (ISO)

4-nitroquinoline N-oxide (ISO)

6-propyl-2-thiouracil (EXP)

actinomycin D (EXP,ISO)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

Butylparaben (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

clofibrate (EXP)

copper(II) sulfate (ISO)

cycloheximide (EXP)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

diuron (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenofibrate (EXP)

fenoprofen (EXP)

fulvestrant (ISO)

genistein (EXP,ISO)

ibuprofen (EXP)

lamivudine (ISO)

Mecamylamine (ISO)

methamphetamine (ISO)

methotrexate (ISO)

methoxychlor (EXP)

methylparaben (ISO)

nicotine (EXP,ISO)

Nutlin-3 (ISO)

obeticholic acid (ISO)

okadaic acid (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

picrotoxin (EXP)

quercetin (ISO)

sevoflurane (ISO)

sodium arsenite (ISO)

Soman (EXP)

streptozocin (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

troglitazone (EXP)

urethane (ISO)

valproic acid (ISO)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to insulin stimulus (IEP)

fatty acid metabolic process (IEA)

fatty acid transport (IGI)

lipid biosynthetic process (IEA)

lipid metabolic process (IEA)

long-chain fatty acid metabolic process (IBA,IDA,IEA,ISO)

long-chain fatty-acyl-CoA biosynthetic process (IBA,IEA,IGI)

neuroblast proliferation (ISO)

neuron development (IEP)

phospholipid biosynthetic process (IMP)

positive regulation of long-chain fatty acid import across plasma membrane (IEA,IMP)

positive regulation of neuron projection development (IMP)

response to gravity (IEP)

response to hypoxia (IEP)

response to nutrient (IEP)

response to steroid hormone (IEP)

triglyceride biosynthetic process (IGI)

very long-chain fatty acid metabolic process (IBA)

Cellular Component

endoplasmic reticulum (IBA,IEA,ISO,ISS)

endoplasmic reticulum membrane (IEA)

membrane (IBA,ISO)

mitochondrial outer membrane (IEA)

peroxisomal membrane (IEA)

Molecular Function

arachidonate-CoA ligase activity (IBA,IDA,IEA)

ATP binding (IEA)

enzyme binding (ISO)

ligase activity (IEA)

long-chain fatty acid-CoA ligase activity (IDA,IEA,ISO)

nucleotide binding (IEA)

protein binding (ISO)

protein homodimerization activity (IDA,IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma (IEA)

fatty acid beta degradation pathway (ISO)

fatty acid metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Up-regulation of fatty acid metabolizing-enzymes mRNA in rat spinal cord during persistent peripheral local inflammation.	Benani A, etal., Eur J Neurosci. 2003 Oct;18(7):1904-14.
2.	Transient maintenance in bioreactor improves health of neuronal cells.	Di Loreto S, etal., In Vitro Cell Dev Biol Anim. 2006 May-Jun;42(5-6):134-42.
3.	Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells.	Dillon JS, etal., Diabetes. 2000 Dec;49(12):2012-20.
4.	Distinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulin.	Durgan DJ, etal., Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2480-97. Epub 2006 Jan 20.
5.	Cloning and functional expression of a novel long-chain acyl-CoA synthetase expressed in brain.	Fujino T and Yamamoto T, J Biochem (Tokyo) 1992 Feb;111(2):197-203.
6.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
8.	Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids.	Klett EL, etal., J Lipid Res. 2017 May;58(5):884-894. doi: 10.1194/jlr.M072512. Epub 2017 Feb 16.
9.	Acyl-CoA synthetase 2 overexpression enhances fatty acid internalization and neurite outgrowth.	Marszalek JR, etal., J Biol Chem. 2004 Jun 4;279(23):23882-91. Epub 2004 Mar 29.
10.	Long-chain acyl-CoA synthetase 6 preferentially promotes DHA metabolism.	Marszalek JR, etal., J Biol Chem. 2005 Mar 18;280(11):10817-26. Epub 2005 Jan 17.
11.	Rat long-chain acyl-CoA synthetase mRNA, protein, and activity vary in tissue distribution and in response to diet.	Mashek DG, etal., J Lipid Res. 2006 Sep;47(9):2004-10. Epub 2006 Jun 13.
12.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
13.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
14.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
15.	GOA pipeline	RGD automated data pipeline
16.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
18.	Comprehensive gene review and curation	RGD comprehensive gene curation
19.	Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus.	Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38.
20.	Activity of the acyl-CoA synthetase ACSL6 isoforms: role of the fatty acid Gate-domains.	Soupene E, etal., BMC Biochem. 2010 Apr 29;11:18. doi: 10.1186/1471-2091-11-18.
21.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
22.	Fatty acid transport by vectorial acylation in mammals: roles played by different isoforms of rat long-chain acyl-CoA synthetases.	Tong F, etal., Arch Biochem Biophys. 2006 Mar 1;447(1):46-52. Epub 2006 Jan 23.
23.	Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome.	Watkins PA, etal., J Lipid Res. 2007 Dec;48(12):2736-50. Epub 2007 Aug 30.
24.	Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).	Yagasaki F, etal., Genes Chromosomes Cancer. 1999 Nov;26(3):192-202.
25.	Molecular cloning and sequencing of cDNA encoding the phosphatidylinositol kinase from rat brain.	Yamakawa A, etal., J Biol Chem 1991 Sep 15;266(26):17580-3.

Additional References at PubMed

PMID:12767919	PMID:14651853	PMID:15683247	PMID:16834775	PMID:22205969	PMID:22633490	PMID:24269233	PMID:27647415	PMID:35976155

Genomics

Comparative Map Data

Acsl6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	38,940,668 - 38,999,515 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	38,940,747 - 39,002,873 (+)	Ensembl				GRCr8
mRatBN7.2	10	38,439,914 - 38,501,182 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	38,440,080 - 38,498,757 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	43,136,726 - 43,184,107 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	42,626,824 - 42,674,198 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	38,130,538 - 38,177,913 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	39,654,771 - 39,717,592 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	39,655,455 - 39,719,312 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	39,430,561 - 39,491,346 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	39,729,805 - 39,778,106 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	37,792,002 - 37,839,268 (+)	NCBI		Celera
RGSC_v3.1	10	39,743,427 - 39,791,726 (+)	NCBI
Cytogenetic Map	10	q22	NCBI

ACSL6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	131,949,973 - 132,012,213 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	131,949,973 - 132,012,243 (-)	Ensembl			hg38	GRCh38
GRCh37	5	131,285,666 - 131,347,906 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	131,317,051 - 131,375,248 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	131,317,050 - 131,375,248	NCBI
Celera	5	127,419,235 - 127,477,416 (-)	NCBI		Celera
Cytogenetic Map	5	q31.1	NCBI
HuRef	5	126,478,229 - 126,540,313 (-)	NCBI		HuRef
CHM1_1	5	130,718,510 - 130,780,578 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	132,469,856 - 132,532,085 (-)	NCBI		T2T-CHM13v2.0

Acsl6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	54,194,580 - 54,255,582 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	54,194,624 - 54,255,582 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	54,303,805 - 54,364,756 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	54,303,798 - 54,364,756 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	54,117,326 - 54,175,041 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	54,147,247 - 54,204,962 (+)	NCBI		MGSCv36	mm8
Celera	11	58,892,926 - 58,950,070 (+)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	32.13	NCBI

Acsl6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	3,333,392 - 3,392,141 (-)	Ensembl
ChiLan1.0	NW_004955408	3,336,214 - 3,391,117 (-)	NCBI	ChiLan1.0	ChiLan1.0

ACSL6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	127,268,577 - 127,330,482 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	125,408,140 - 125,470,045 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	127,373,306 - 127,434,954 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	133,537,292 - 133,599,093 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	133,537,292 - 133,586,711 (-)	Ensembl			panPan2	panpan1.1

ACSL6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	20,226,877 - 20,284,919 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	20,227,268 - 20,285,631 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	19,022,424 - 19,080,475 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	21,004,617 - 21,062,652 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	21,003,713 - 21,062,951 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	19,731,639 - 19,789,658 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	19,579,269 - 19,637,509 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	20,220,723 - 20,279,041 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Acsl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	116,150,811 - 116,206,180 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936647	3,153,485 - 3,213,582 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936647	3,153,586 - 3,208,935 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACSL6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	134,210,917 - 134,278,820 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	134,210,915 - 134,278,860 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	139,569,528 - 139,633,727 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACSL6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	34,787,097 - 34,846,387 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	34,787,432 - 34,829,042 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666034	43,111,126 - 43,174,349 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acsl6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	40,105,806 - 40,160,221 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624733	40,105,795 - 40,157,108 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Acsl6
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	36,760,359 - 36,818,617 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Acsl6
369 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	464
Count of miRNA genes:	141
Interacting mature miRNAs:	171
Transcripts:	ENSRNOT00000030760, ENSRNOT00000058817
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35893451	64140567	Rat
152025229	Scl83	Serum cholesterol level QTL 83	4.33		blood cholesterol amount (VT:0000180)		10	36211556	69161158	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31796281	76796281	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15776754	60776754	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	27023535	98502431	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	27443787	72443787	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	35509383	91417879	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	19939207	64939207	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	18035782	63035782	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18668419	63668419	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21833758	61843633	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28950353	73950353	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35893263	64653589	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29800910	64653589	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	27443787	72443787	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22931373	91127454	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
634329	Pia15	Pristane induced arthritis QTL 15	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	24662123	73695339	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	27023535	61843633	Rat
2298480	Eau7	Experimental allergic uveoretinitis QTL 7		0.0049	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	35509383	80509383	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29800910	91417879	Rat
2298495	Eae23	Experimental allergic encephalomyelitis QTL 23	16.93		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	10	16175525	61175525	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	20110614	65110614	Rat
1354614	Hpcl1	Hepatic cholesterol level QTL 1	3.3		liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	35893263	52293000	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	27587226	96099902	Rat
2289985	Bp305	Blood pressure QTL 305			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	29076978	74076978	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	18035782	63035782	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	27443787	72443787	Rat
1600371	Mcs21	Mammary carcinoma susceptibility QTL 21	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	29377046	52699134	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31129113	76129113	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	35509383	88177745	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	20110614	65110614	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	27023535	99451848	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	12	67	164	57	54	25	50	25	6	257	150	10	142	59	84	29	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001439547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439548	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439549	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439555	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_130739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246224	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063268323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063268324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY625254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D10041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EF490998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB881417	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC938826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	S56508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000030760 ⟹ ENSRNOP00000033248

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	38,952,031 - 39,002,873 (+)	Ensembl
mRatBN7.2 Ensembl	10	38,451,416 - 38,498,757 (+)	Ensembl
Rnor_6.0 Ensembl	10	39,666,991 - 39,715,973 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000058817 ⟹ ENSRNOP00000055608

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	38,940,747 - 39,002,873 (+)	Ensembl
mRatBN7.2 Ensembl	10	38,440,326 - 38,498,757 (+)	Ensembl
Rnor_6.0 Ensembl	10	39,655,455 - 39,719,312 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103397 ⟹ ENSRNOP00000096136

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	38,940,859 - 39,002,873 (+)	Ensembl
mRatBN7.2 Ensembl	10	38,440,080 - 38,498,757 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107770 ⟹ ENSRNOP00000080278

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	38,951,954 - 38,999,493 (+)	Ensembl
mRatBN7.2 Ensembl	10	38,456,634 - 38,498,757 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115137 ⟹ ENSRNOP00000081838

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	38,957,106 - 39,002,873 (+)	Ensembl
mRatBN7.2 Ensembl	10	38,456,361 - 38,498,757 (+)	Ensembl

RefSeq Acc Id:

NM_130739 ⟹ NP_570095

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,952,161 - 38,999,502 (+)	NCBI
mRatBN7.2	10	38,451,416 - 38,498,762 (+)	NCBI
Rnor_6.0	10	39,666,991 - 39,715,982 (+)	NCBI
Rnor_5.0	10	39,430,561 - 39,491,346 (+)	NCBI
RGSC_v3.4	10	39,729,805 - 39,778,106 (+)	RGD
Celera	10	37,792,002 - 37,839,268 (+)	RGD

Sequence:

show sequence

GCCTTCCATCAAGATGTGGTAACCTCTTTCCCTGAGCGCCACAGGCTCTAGAAAGAGAGGCTGG
TTCTAGCAGGATCAACTCCACTCCTCAGTGCCCGGAGGCTGCTGGAAAGAGATTGCCCTGTCAC
TTCTGGAGAAGATGCAGACCCAGGAGATCCTGAGGATCCTGCGGCTGCCCGAGCTATCGGACTT
GGGCCAGTTTTTCCGCAGCCTCTCAGCCACCACCCTTGTGAGTATGGGTGCACTGGCTGCCATC
CTTGCATACTGGCTCACTCACCGGCCAAAGGCCTTGCAACCACCATGCAACCTCCTGATGCAGT
CGGAAGAAGTAGAGGACAGTGGTGGAGCCCGGCGATCTGTGATTGGGGATTGCACTCAGTTGCT
TACCCACTACTATGACGATGCCCGGACGATGTACCAGGTGTTCCGACGTGGGCTTAGCATCTCA
GGGAATGGACCCTGTCTTGGCTTCCGGAAGCCAGAGCAACCTTACCAGTGGCTGTCCTATCAAG
AGGTGGCCAAAAGGGCTGAATTCCTGGGGTCAGGACTTCTCCAGCATGACTGTAAAGTGGGCAC
AGAGCAGTTCATTGGCGTTTTTGCACAAAATCGGCCAGAGTGGATCATTGCTGAGCTGGCCTGC
TACACATATTCCATGGTGGTGGTACCGCTCTATGACACACTGGGCCCAGGGTCTATCCGCTACA
TCATCAATACAGCGGACATCTGCACTGTAATCGTGGATAAGCCGCATAAGGCTATACTCCTGCT
AGAACACGTGGAGAGGAAGGAGACTCCGGGCCTCAAGCTGGTCATCCTCATGGAGCCATTTGAC
GATGCCCTGAGAGAGAGGGGAAAGAAGTGCGGGGTGGACATCAAGTCCATGCAGGCTATAGAGG
ACTCCGGCCAAGAGAATCATCGTGTCCCCGTGCCCCCACGGCCCGATGACCTCTCCATTGTGTG
TTTCACGAGCGGTACAACAGGGAACCCCAAAGGTGCGATGCTCACCCACGGGAACGTGGTGGCC
GATTTCTCGGGCTTTCTGAAAGTCACAGAGAGTCAGTGGGCCCCCACTTGTGCGGATGTACACT
TTTCCTATTTGCCTTTAGCACACATGTTTGAGCGAATGGTGCAGTCTGTTGTCTACTGCCATGG
AGGGCGTGTGGGCTTCTTCCAGGGAGACATCCGCCTCCTCTCAGACGACATGAAAGCTCTCCGC
CCCACCATCTTCCCTGTGGTCCCACGGCTGCTGAATCGGATGTATGACAAGATCTTCCACCAGG
CAGACACCTCACTGAAGCGCTGGCTCCTGGAGTTTGCAGCAAAGCGCAAGCAGGCTGAGGTCCG
GAGCGGAATCATCAGAAACAATAGTATCTGGGATGAACTCTTCTTTAATAAGATTCAGGCCAGT
CTTGGAGGGCACGTGAGAATGATTGTTACCGGAGCAGCCCCCGCATCACCAACAGTCCTGGGAT
TCCTACGAGCAGCTCTGGGGTGCCAGGTCTATGAAGGTTATGGGCAAACTGAATGCACAGCTGG
GTGTACCTTCACAACGCCAGGGGACTGGACATCAGGGCACGTGGGAGCCCCTCTGCCCTGCAAC
CACATCAAGCTGGTCGACGCAGAGGAACTCAACTACTGGACCAGCAAAGGAGAAGGAGAGATCT
GTGTGAAAGGACCAAATGTGTTCAAAGGCTACTTAAAAGACGAGGACAGGACAAAGGAGGCCCT
GGACAGTGACGGCTGGCTTCACACGGGAGACATTGGAAAATGGCTGCCGGAGGGAACGCTTAAA
ATCATCGATCGGAAAAAGGACATATTTAAACTTGCTCAGGGGGAATACGTTGCGCCCGAGAAGA
TTGAGAACATCTACATCCGAAGTGAGCCTGTGGCGCAAATCTACGTCCATGGGGACAGCTTAAA
GGCCTTTCTGGTTGGCATTGTTGTGCCTGACCCTGAAGTCATGCCTTGCTGGGCTCAGAAGAAA
GGAATCGAAGGGAACTACCAGGAACTCTGCAAAAGTAAGGAATTGAAGAAAGCCATTCTGGATG
ACATGGTGATGTTGGGGAAAGAAAGTGGACTGCATTCTTTTGAACAGGTTAAAGCCATTTACAT
CCATTGTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAGGCTAAGAGGCCC
GAGCTGAGAGAGTACTTCAAAAAGCAAATAGAAGAGCTGTACTCAATCTCCATGTGAAGCTCAA
GGAGGCCCTTCTCAGCCCAGCAAAGTTTGCAGCAATATTCTAATTATTCTTGAGAGAAAAGGAG
TCAGAATGCCACAGCTCAGAGTGAACGAGCACCTGATTTTTTTTTTTTTTTGCAACTGAGCCTT
TCCTGACCTGAGAAGTCTCTAACAATATTTTCTCTACCATCACCAAGTACCACTTTATTTTTAT
TAAATGATATTGTAGCAAGCTGCTAAAAAAAATTATTGCAAACGGTAATGTAAAAACAAATCAA
GACCTTTCTCAAGAACTGTGTACCACTAAAGTAATATATTCGCGATGTTCACAGAATTCCATTA
AACATAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006246221 ⟹ XP_006246283

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,940,813 - 38,999,515 (+)	NCBI
mRatBN7.2	10	38,440,234 - 38,501,182 (+)	NCBI
Rnor_6.0	10	39,655,298 - 39,717,592 (+)	NCBI
Rnor_5.0	10	39,430,561 - 39,491,346 (+)	NCBI

Sequence:

show sequence

GGATGCCGCTGTCTCTGTGCCCAGGAGTCCCGGCCGCGCTGCGGGGCTGGGAGTCGGGTTCCGT
GAGGAGCGCGCGCTGCGCCCTCCCCCTCCCGCCGGGTCTCCGCAGCGGCGCGGGGAGGCGGGGG
CTAAAAATACCCGGCGGCGGCGGCAGCGGCAGTGGCTCTGGGGCTGCGGGGTTGCGGGCCTGGG
AAGCAGTGCGGCCCGGGCTGGGCCCGCTCACCGACATGCTGACCTTCTTCTTGGTGTCGGGGGG
TTCCCTCTGGCTGTTTGCCGAGATTGCCCTGTCACTTCTGGAGAAGATGCAGACCCAGGAGATC
CTGAGGATCCTGCGGCTGCCCGAGCTATCGGACTTGGGCCAGTTTTTCCGCAGCCTCTCAGCCA
CCACCCTTGTGAGTATGGGTGCACTGGCTGCCATCCTTGCATACTGGCTCACTCACCGGCCAAA
GGCCTTGCAACCACCATGCAACCTCCTGATGCAGTCGGAAGAAGTAGAGGACAGTGGTGGAGCC
CGGCGATCTGTGATTGGGGATTGCACTCAGTTGCTTACCCACTACTATGACGATGCCCGGACGA
TGTACCAGGTGTTCCGACGTGGGCTTAGCATCTCAGGGAATGGACCCTGTCTTGGCTTCCGGAA
GCCAGAGCAACCTTACCAGTGGCTGTCCTATCAAGAGGTGGCCAAAAGGGCTGAATTCCTGGGG
TCAGGACTTCTCCAGCATGACTGTAAAGTGGGCACAGAGCAGTTCATTGGCGTTTTTGCACAAA
ATCGGCCAGAGTGGATCATTGCTGAGCTGGCCTGCTACACATATTCCATGGTGGTGGTACCGCT
CTATGACACACTGGGCCCAGGGTCTATCCGCTACATCATCAATACAGCGGACATCTGCACTGTA
ATCGTGGATAAGCCGCATAAGGCTATACTCCTGCTAGAACACGTGGAGAGGAAGGAGACTCCGG
GCCTCAAGCTGGTCATCCTCATGGAGCCATTTGACGATGCCCTGAGAGAGAGGGGAAAGAAGTG
CGGGGTGGACATCAAGTCCATGCAGGCTATAGAGGACTCCGGCCAAGAGAATCATCGTGTCCCC
GTGCCCCCACGGCCCGATGACCTCTCCATTGTGTGTTTCACGAGCGGTACAACAGGGAACCCCA
AAGGTGCGATGCTCACCCACGGGAACGTGGTGGCCGATTTCTCGGGCTTTCTGAAAGTCACAGA
GAAAGTGATCTTTCCGAGACAGGACGATGTGCTCATCTCCTTCCTGCCTCTGGCTCACATGTTT
GAGAGAGTGATCCAGTCTGTTGTCTACTGCCATGGAGGGCGTGTGGGCTTCTTCCAGGGAGACA
TCCGCCTCCTCTCAGACGACATGAAAGCTCTCCGCCCCACCATCTTCCCTGTGGTCCCACGGCT
GCTGAATCGGATGTATGACAAGATCTTCCACCAGGCAGACACCTCACTGAAGCGCTGGCTCCTG
GAGTTTGCAGCAAAGCGCAAGCAGGCTGAGGTCCGGAGCGGAATCATCAGAAACAATAGTATCT
GGGATGAACTCTTCTTTAATAAGATTCAGGCCAGTCTTGGAGGGCACGTGAGAATGATTGTTAC
CGGAGCAGCCCCCGCATCACCAACAGTCCTGGGATTCCTACGAGCAGCTCTGGGGTGCCAGGTC
TATGAAGGTTATGGGCAAACTGAATGCACAGCTGGGTGTACCTTCACAACGCCAGGGGACTGGA
CATCAGGGCACGTGGGAGCCCCTCTGCCCTGCAACCACATCAAGCTGGTCGACGCAGAGGAACT
CAACTACTGGACCAGCAAAGGAGAAGGAGAGATCTGTGTGAAAGGACCAAATGTGTTCAAAGGC
TACTTAAAAGACGAGGACAGGACAAAGGAGGCCCTGGACAGTGACGGCTGGCTTCACACGGGAG
ACATTGGAAAATGGCTGCCGGAGGGAACGCTTAAAATCATCGATCGGAAAAAGCACATATTTAA
ACTTGCTCAGGGGGAATACGTTGCGCCCGAGAAGATTGAGAACATCTACATCCGAAGTGAGCCT
GTGGCGCAAATCTACGTCCATGGGGACAGCTTAAAGGCCTTTCTGGTTGGCATTGTTGTGCCTG
ACCCTGAAGTCATGCCTTGCTGGGCTCAGAAGAAAGGAATCGAAGGGAACTACCAGGAACTCTG
CAAAAGTAAGGAATTGAAGAAAGCCATTCTGGATGACATGGTGATGTTGGGGAAAGAAAGTGGA
CTGCATTCTTTTGAACAGGTTAAAGCCATTTACATCCATTGTGACATGTTCTCAGTTCAAAATG
GCTTGCTGACACCAACACTAAAGGCTAAGAGGCCCGAGCTGAGAGAGTACTTCAAAAAGCAAAT
AGAAGAGCTGTACTCAATCTCCATGTGAAGCTCAAGGAGGCCCTTCTCAGCCCAGCAAAGTTTG
CAGCAATATTCTAATTATTCTTGAGAGAAAGGAGTCAGAATGCCACAGCTCAGAGTGAACGAGC
ACCTGATTTTTTTTTTTTGCAACTGAGCCTTTCCTGACCTGAGAAGTCTCTAACAATATTTTCT
CTACCATCACCAAGTACACTTTATTTTTATTAAATGATATTGTAGCAAGCTGCTAAAAAAATTA
TTGCAAACGGTAATGTAAAAACAAATCAAGACACTTTCTCAAGAACTGTGTACCACTAAAGTAA
TATATTCGCGATGTTCACAGAATTCCATTAAACATAAAGAAAAAAAAGTAACCGATATATTGTA
CTTAATTATTTGTGGACTAATAACCAGGTACAGTGAAAGTCTAGGCAACGTGGACTACCTCATT
AAATAACGATTGTCACCAGTCACAGTTAGATCAGACCTAAAACTGAAACCAAGGTGTAGGAAGT
CACACCAAAACAAAACACGATAGTTCCCACGTGACCCGACCCCCATCCTCTAACGTGAACACCT
TTGCCGACACGATGCCAACTCCTCACTGATTTTTACTTTTACTCATGAAAAGCGGAAATGCAGC
TGTTCTTAAAGCAAATATCATATTTAACAACTCCATAGGCCGTTGAGTAATTTTCTCACTTGTC
AAGTTCACCGAAACATTCAGAGTCTTTGTACAGAAGTATAGGTAGGGGTTGCATTTATCTCTGC
ACTTCTTACCATAAGGAAGCTTAAGAGATGTGCGTCGGCGGCGACAGCAAATGGACTCTTGGCG
AACATTTGAGGGAGGGTACTCAGTGTTTTCTCAGGGTGGGCAACAGTCCGCGTACCCATGTTTC
TGCTAGAGTCTTTGCCTTTCCCACTCTCAATATGTCTGTGACAGGTCTGGGAAACGCAATACGG
CTGAAATTGTGAACAACCTCGATTTCTTTTCCTATGACATCAAAGCAAAGAGAGGAAGACTATC
TGCTATTTCCAAATAAAAGAACTCTTCAATGACATGGTACAGAAGCACTTCTTCAAAGTTCCCC
TAGAAACCTATGGAAGCCCAACATAGAGAAATCCCTGCTAATGGCCTAATTCCATTCCTAGAAA
CTCCAGATGCTCCTAATCGACCAGAAAACCTTAATTGTGTTATATGTTTAGTTGCACCCTAAAT
CTGGGTGCCAAGATTCTGATGTCACCAAAAAGCCTCGATACCATGAACAGTCAGCACTATAAAC
TGTGCACCTGAGGAGGGGCAAGGTCCCTGGGGAAGTATTTCTCTTCCGTGGGGGCAGGACTCTG
AAAGTATGCAGAGAACTCGTGCAGGTCACATGATCTCCCCAAATGCATCTGTGATGGGTATGGC
AGGACAAGAACTCCTTAGCTCTGAGGGAAATCCAACTTATTTGCGTAAGTGAATGTTCTCAGTT
GGAACCTGCGTCATCACACAGGCCTGTTGGATGGTCCCAACATGTATGTGAGTGAACGTTCTCA
GTCAGAACCTGCCTCATCCATCAGGCAGGCCTGTTGGATGGTCTGTGTCATTGATCATACATCT
GTTTCAGTCAAGTTGAGTCATGACCTGAGCTTCAATTGATGTAGTTATCCGGGTACTTTTTCCC
CCACACATTCCTTGAGCATCATCTCTCTGAAAACTCAATGTTGCACCTACTAACTTGACGTTGA
CTAAATGAGCAATTCTGTGCCCATTAGTTTCTTTCACAGTATGGAGGAGCAAAACCAGGACCTC
GCACAGGCTAGGCAAGAACTGCTCTGCTGAGCTCCACTTCCAGCGCTGTGTGCATTAACTTTGA
AATGCATTTCTGGTGAGGCAAATAACACCTTGAAAGCCCAGATCTGAGGAGCACTGGCTTTTTA
AATGTTTAATGTATGTTCGATCAATTAAAATTGAACGTCATTACCTGA

hide sequence

RefSeq Acc Id:

XM_006246222 ⟹ XP_006246284

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,940,919 - 38,999,515 (+)	NCBI
mRatBN7.2	10	38,440,233 - 38,501,182 (+)	NCBI
Rnor_6.0	10	39,655,295 - 39,717,592 (+)	NCBI
Rnor_5.0	10	39,430,561 - 39,491,346 (+)	NCBI

Sequence:

show sequence

TTCGGATGCCGCTGTCTCTGTGCCCAGGAGTCCCGGCCGCGCTGCGGGGCTGGGAGTCGGGTTC
CGTGAGGAGCGCGCGCTGCGCCCTCCCCCTCCCGCCGGGTCTCCGCAGCGGCGCGGGGAGGCGG
GGGCTAAAAATACCCGGCGGCGGCGGCAGCGGCAGTGGCTCTGGGGCTGCGGGGTTGCGGGCCT
GGGAAGCAGTGCGGCCCGGGCTGGGCCCGCTCACCGACATGCTGACCTTCTTCTTGGTGTCGGG
GGGTTCCCTCTGGCTGTTTGCCGAGATTGCCCTGTCACTTCTGGAGAAGATGCAGACCCAGGAG
ATCCTGAGGATCCTGCGGCTGCCCGAGCTATCGGACTTGGGCCAGTTTTTCCGCAGCCTCTCAG
CCACCACCCTTGTGAGTATGGGTGCACTGGCTGCCATCCTTGCATACTGGCTCACTCACCGGCC
AAAGGCCTTGCAACCACCATGCAACCTCCTGATGCAGTCGGAAGAAGTAGAGGACAGTGGTGGA
GCCCGGCGATCTGTGATTGGGGATTGCACTCAGTTGCTTACCCACTACTATGACGATGCCCGGA
CGATGTACCAGGTGTTCCGACGTGGGCTTAGCATCTCAGGGAATGGACCCTGTCTTGGCTTCCG
GAAGCCAGAGCAACCTTACCAGTGGCTGTCCTATCAAGAGGTGGCCAAAAGGGCTGAATTCCTG
GGGTCAGGACTTCTCCAGCATGACTGTAAAGTGGGCACAGAGCAGTTCATTGGCGTTTTTGCAC
AAAATCGGCCAGAGTGGATCATTGCTGAGCTGGCCTGCTACACATATTCCATGGTGGTGGTACC
GCTCTATGACACACTGGGCCCAGGGTCTATCCGCTACATCATCAATACAGCGGACATCTGCACT
GTAATCGTGGATAAGCCGCATAAGGCTATACTCCTGCTAGAACACGTGGAGAGGAAGGAGACTC
CGGGCCTCAAGCTGGTCATCCTCATGGAGCCATTTGACGATGCCCTGAGAGAGAGGGGAAAGAA
GTGCGGGGTGGACATCAAGTCCATGCAGGCTATAGAGGACTCCGGCCAAGAGAATCATCGTGTC
CCCGTGCCCCCACGGCCCGATGACCTCTCCATTGTGTGTTTCACGAGCGGTACAACAGGGAACC
CCAAAGGTGCGATGCTCACCCACGGGAACGTGGTGGCCGATTTCTCGGGCTTTCTGAAAGTCAC
AGAGAGTCAGTGGGCCCCCACTTGTGCGGATGTACACTTTTCCTATTTGCCTTTAGCACACATG
TTTGAGCGAATGGTGCAGTCTGTTGTCTACTGCCATGGAGGGCGTGTGGGCTTCTTCCAGGGAG
ACATCCGCCTCCTCTCAGACGACATGAAAGCTCTCCGCCCCACCATCTTCCCTGTGGTCCCACG
GCTGCTGAATCGGATGTATGACAAGATCTTCCACCAGGCAGACACCTCACTGAAGCGCTGGCTC
CTGGAGTTTGCAGCAAAGCGCAAGCAGGCTGAGGTCCGGAGCGGAATCATCAGAAACAATAGTA
TCTGGGATGAACTCTTCTTTAATAAGATTCAGGCCAGTCTTGGAGGGCACGTGAGAATGATTGT
TACCGGAGCAGCCCCCGCATCACCAACAGTCCTGGGATTCCTACGAGCAGCTCTGGGGTGCCAG
GTCTATGAAGGTTATGGGCAAACTGAATGCACAGCTGGGTGTACCTTCACAACGCCAGGGGACT
GGACATCAGGGCACGTGGGAGCCCCTCTGCCCTGCAACCACATCAAGCTGGTCGACGCAGAGGA
ACTCAACTACTGGACCAGCAAAGGAGAAGGAGAGATCTGTGTGAAAGGACCAAATGTGTTCAAA
GGCTACTTAAAAGACGAGGACAGGACAAAGGAGGCCCTGGACAGTGACGGCTGGCTTCACACGG
GAGACATTGGAAAATGGCTGCCGGAGGGAACGCTTAAAATCATCGATCGGAAAAAGCACATATT
TAAACTTGCTCAGGGGGAATACGTTGCGCCCGAGAAGATTGAGAACATCTACATCCGAAGTGAG
CCTGTGGCGCAAATCTACGTCCATGGGGACAGCTTAAAGGCCTTTCTGGTTGGCATTGTTGTGC
CTGACCCTGAAGTCATGCCTTGCTGGGCTCAGAAGAAAGGAATCGAAGGGAACTACCAGGAACT
CTGCAAAAGTAAGGAATTGAAGAAAGCCATTCTGGATGACATGGTGATGTTGGGGAAAGAAAGT
GGACTGCATTCTTTTGAACAGGTTAAAGCCATTTACATCCATTGTGACATGTTCTCAGTTCAAA
ATGGCTTGCTGACACCAACACTAAAGGCTAAGAGGCCCGAGCTGAGAGAGTACTTCAAAAAGCA
AATAGAAGAGCTGTACTCAATCTCCATGTGAAGCTCAAGGAGGCCCTTCTCAGCCCAGCAAAGT
TTGCAGCAATATTCTAATTATTCTTGAGAGAAAGGAGTCAGAATGCCACAGCTCAGAGTGAACG
AGCACCTGATTTTTTTTTTTTGCAACTGAGCCTTTCCTGACCTGAGAAGTCTCTAACAATATTT
TCTCTACCATCACCAAGTACACTTTATTTTTATTAAATGATATTGTAGCAAGCTGCTAAAAAAA
TTATTGCAAACGGTAATGTAAAAACAAATCAAGACACTTTCTCAAGAACTGTGTACCACTAAAG
TAATATATTCGCGATGTTCACAGAATTCCATTAAACATAAAGAAAAAAAAGTAACCGATATATT
GTACTTAATTATTTGTGGACTAATAACCAGGTACAGTGAAAGTCTAGGCAACGTGGACTACCTC
ATTAAATAACGATTGTCACCAGTCACAGTTAGATCAGACCTAAAACTGAAACCAAGGTGTAGGA
AGTCACACCAAAACAAAACACGATAGTTCCCACGTGACCCGACCCCCATCCTCTAACGTGAACA
CCTTTGCCGACACGATGCCAACTCCTCACTGATTTTTACTTTTACTCATGAAAAGCGGAAATGC
AGCTGTTCTTAAAGCAAATATCATATTTAACAACTCCATAGGCCGTTGAGTAATTTTCTCACTT
GTCAAGTTCACCGAAACATTCAGAGTCTTTGTACAGAAGTATAGGTAGGGGTTGCATTTATCTC
TGCACTTCTTACCATAAGGAAGCTTAAGAGATGTGCGTCGGCGGCGACAGCAAATGGACTCTTG
GCGAACATTTGAGGGAGGGTACTCAGTGTTTTCTCAGGGTGGGCAACAGTCCGCGTACCCATGT
TTCTGCTAGAGTCTTTGCCTTTCCCACTCTCAATATGTCTGTGACAGGTCTGGGAAACGCAATA
CGGCTGAAATTGTGAACAACCTCGATTTCTTTTCCTATGACATCAAAGCAAAGAGAGGAAGACT
ATCTGCTATTTCCAAATAAAAGAACTCTTCAATGACATGGTACAGAAGCACTTCTTCAAAGTTC
CCCTAGAAACCTATGGAAGCCCAACATAGAGAAATCCCTGCTAATGGCCTAATTCCATTCCTAG
AAACTCCAGATGCTCCTAATCGACCAGAAAACCTTAATTGTGTTATATGTTTAGTTGCACCCTA
AATCTGGGTGCCAAGATTCTGATGTCACCAAAAAGCCTCGATACCATGAACAGTCAGCACTATA
AACTGTGCACCTGAGGAGGGGCAAGGTCCCTGGGGAAGTATTTCTCTTCCGTGGGGGCAGGACT
CTGAAAGTATGCAGAGAACTCGTGCAGGTCACATGATCTCCCCAAATGCATCTGTGATGGGTAT
GGCAGGACAAGAACTCCTTAGCTCTGAGGGAAATCCAACTTATTTGCGTAAGTGAATGTTCTCA
GTTGGAACCTGCGTCATCACACAGGCCTGTTGGATGGTCCCAACATGTATGTGAGTGAACGTTC
TCAGTCAGAACCTGCCTCATCCATCAGGCAGGCCTGTTGGATGGTCTGTGTCATTGATCATACA
TCTGTTTCAGTCAAGTTGAGTCATGACCTGAGCTTCAATTGATGTAGTTATCCGGGTACTTTTT
CCCCCACACATTCCTTGAGCATCATCTCTCTGAAAACTCAATGTTGCACCTACTAACTTGACGT
TGACTAAATGAGCAATTCTGTGCCCATTAGTTTCTTTCACAGTATGGAGGAGCAAAACCAGGAC
CTCGCACAGGCTAGGCAAGAACTGCTCTGCTGAGCTCCACTTCCAGCGCTGTGTGCATTAACTT
TGAAATGCATTTCTGGTGAGGCAAATAACACCTTGAAAGCCCAGATCTGAGGAGCACTGGCTTT
TTAAATGTTTAATGTATGTTCGATCAATTAAAATTGAACGTCATTACCTGA

hide sequence

RefSeq Acc Id:

XM_006246224 ⟹ XP_006246286

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,940,668 - 38,999,515 (+)	NCBI
mRatBN7.2	10	38,439,914 - 38,501,182 (+)	NCBI
Rnor_6.0	10	39,654,771 - 39,717,426 (+)	NCBI
Rnor_5.0	10	39,430,561 - 39,491,346 (+)	NCBI

Sequence:

show sequence

CATCACTGCCTGTGTCCTTGGGAGACACCTGTGATTCCATGTGGCTGCCTGTGGCTTCATGTGA
CATGCCTAGGGACATGGCAGCTGATGTGACTCCTAGCGACTACAAAATCAGGTCCTAGGGGGCG
TCTGAGTCAGCCAGGATCCGGCCCTTCAGCATGTGCACTCTCTGGGACAGAAGCCCTGGACCCC
CGCTGCCATTTGAGCCTGCCTAGCCATAAAACCCCGGAGGCCGATCGTGCGGAGAGATTGCCCT
GTCACTTCTGGAGAAGATGCAGACCCAGGAGATCCTGAGGATCCTGCGGCTGCCCGAGCTATCG
GACTTGGGCCAGTTTTTCCGCAGCCTCTCAGCCACCACCCTTGTGAGTATGGGTGCACTGGCTG
CCATCCTTGCATACTGGCTCACTCACCGGCCAAAGGCCTTGCAACCACCATGCAACCTCCTGAT
GCAGTCGGAAGAAGTAGAGGACAGTGGTGGAGCCCGGCGATCTGTGATTGGGGATTGCACTCAG
TTGCTTACCCACTACTATGACGATGCCCGGACGATGTACCAGGTGTTCCGACGTGGGCTTAGCA
TCTCAGGGAATGGACCCTGTCTTGGCTTCCGGAAGCCAGAGCAACCTTACCAGTGGCTGTCCTA
TCAAGAGGTGGCCAAAAGGGCTGAATTCCTGGGGTCAGGACTTCTCCAGCATGACTGTAAAGTG
GGCACAGAGCAGTTCATTGGCGTTTTTGCACAAAATCGGCCAGAGTGGATCATTGCTGAGCTGG
CCTGCTACACATATTCCATGGTGGTGGTACCGCTCTATGACACACTGGGCCCAGGGTCTATCCG
CTACATCATCAATACAGCGGACATCTGCACTGTAATCGTGGATAAGCCGCATAAGGCTATACTC
CTGCTAGAACACGTGGAGAGGAAGGAGACTCCGGGCCTCAAGCTGGTCATCCTCATGGAGCCAT
TTGACGATGCCCTGAGAGAGAGGGGAAAGAAGTGCGGGGTGGACATCAAGTCCATGCAGGCTAT
AGAGGACTCCGGCCAAGAGAATCATCGTGTCCCCGTGCCCCCACGGCCCGATGACCTCTCCATT
GTGTGTTTCACGAGCGGTACAACAGGGAACCCCAAAGGTGCGATGCTCACCCACGGGAACGTGG
TGGCCGATTTCTCGGGCTTTCTGAAAGTCACAGAGAAAGTGATCTTTCCGAGACAGGACGATGT
GCTCATCTCCTTCCTGCCTCTGGCTCACATGTTTGAGAGAGTGATCCAGTCTGTTGTCTACTGC
CATGGAGGGCGTGTGGGCTTCTTCCAGGGAGACATCCGCCTCCTCTCAGACGACATGAAAGCTC
TCCGCCCCACCATCTTCCCTGTGGTCCCACGGCTGCTGAATCGGATGTATGACAAGATCTTCCA
CCAGGCAGACACCTCACTGAAGCGCTGGCTCCTGGAGTTTGCAGCAAAGCGCAAGCAGGCTGAG
GTCCGGAGCGGAATCATCAGAAACAATAGTATCTGGGATGAACTCTTCTTTAATAAGATTCAGG
CCAGTCTTGGAGGGCACGTGAGAATGATTGTTACCGGAGCAGCCCCCGCATCACCAACAGTCCT
GGGATTCCTACGAGCAGCTCTGGGGTGCCAGGTCTATGAAGGTTATGGGCAAACTGAATGCACA
GCTGGGTGTACCTTCACAACGCCAGGGGACTGGACATCAGGGCACGTGGGAGCCCCTCTGCCCT
GCAACCACATCAAGCTGGTCGACGCAGAGGAACTCAACTACTGGACCAGCAAAGGAGAAGGAGA
GATCTGTGTGAAAGGACCAAATGTGTTCAAAGGCTACTTAAAAGACGAGGACAGGACAAAGGAG
GCCCTGGACAGTGACGGCTGGCTTCACACGGGAGACATTGGAAAATGGCTGCCGGAGGGAACGC
TTAAAATCATCGATCGGAAAAAGCACATATTTAAACTTGCTCAGGGGGAATACGTTGCGCCCGA
GAAGATTGAGAACATCTACATCCGAAGTGAGCCTGTGGCGCAAATCTACGTCCATGGGGACAGC
TTAAAGGCCTTTCTGGTTGGCATTGTTGTGCCTGACCCTGAAGTCATGCCTTGCTGGGCTCAGA
AGAAAGGAATCGAAGGGAACTACCAGGAACTCTGCAAAAGTAAGGAATTGAAGAAAGCCATTCT
GGATGACATGGTGATGTTGGGGAAAGAAAGTGGACTGCATTCTTTTGAACAGGTTAAAGCCATT
TACATCCATTGTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAGGCTAAGA
GGCCCGAGCTGAGAGAGTACTTCAAAAAGCAAATAGAAGAGCTGTACTCAATCTCCATGTGAAG
CTCAAGGAGGCCCTTCTCAGCCCAGCAAAGTTTGCAGCAATATTCTAATTATTCTTGAGAGAAA
GGAGTCAGAATGCCACAGCTCAGAGTGAACGAGCACCTGATTTTTTTTTTTTGCAACTGAGCCT
TTCCTGACCTGAGAAGTCTCTAACAATATTTTCTCTACCATCACCAAGTACACTTTATTTTTAT
TAAATGATATTGTAGCAAGCTGCTAAAAAAATTATTGCAAACGGTAATGTAAAAACAAATCAAG
ACACTTTCTCAAGAACTGTGTACCACTAAAGTAATATATTCGCGATGTTCACAGAATTCCATTA
AACATAAAGAAAAAAAAGTAACCGATATATTGTACTTAATTATTTGTGGACTAATAACCAGGTA
CAGTGAAAGTCTAGGCAACGTGGACTACCTCATTAAATAACGATTGTCACCAGTCACAGTTAGA
TCAGACCTAAAACTGAAACCAAGGTGTAGGAAGTCACACCAAAACAAAACACGATAGTTCCCAC
GTGACCCGACCCCCATCCTCTAACGTGAACACCTTTGCCGACACGATGCCAACTCCTCACTGAT
TTTTACTTTTACTCATGAAAAGCGGAAATGCAGCTGTTCTTAAAGCAAATATCATATTTAACAA
CTCCATAGGCCGTTGAGTAATTTTCTCACTTGTCAAGTTCACCGAAACATTCAGAGTCTTTGTA
CAGAAGTATAGGTAGGGGTTGCATTTATCTCTGCACTTCTTACCATAAGGAAGCTTAAGAGATG
TGCGTCGGCGGCGACAGCAAATGGACTCTTGGCGAACATTTGAGGGAGGGTACTCAGTGTTTTC
TCAGGGTGGGCAACAGTCCGCGTACCCATGTTTCTGCTAGAGTCTTTGCCTTTCCCACTCTCAA
TATGTCTGTGACAGGTCTGGGAAACGCAATACGGCTGAAATTGTGAACAACCTCGATTTCTTTT
CCTATGACATCAAAGCAAAGAGAGGAAGACTATCTGCTATTTCCAAATAAAAGAACTCTTCAAT
GACATGGTACAGAAGCACTTCTTCAAAGTTCCCCTAGAAACCTATGGAAGCCCAACATAGAGAA
ATCCCTGCTAATGGCCTAATTCCATTCCTAGAAACTCCAGATGCTCCTAATCGACCAGAAAACC
TTAATTGTGTTATATGTTTAGTTGCACCCTAAATCTGGGTGCCAAGATTCTGATGTCACCAAAA
AGCCTCGATACCATGAACAGTCAGCACTATAAACTGTGCACCTGAGGAGGGGCAAGGTCCCTGG
GGAAGTATTTCTCTTCCGTGGGGGCAGGACTCTGAAAGTATGCAGAGAACTCGTGCAGGTCACA
TGATCTCCCCAAATGCATCTGTGATGGGTATGGCAGGACAAGAACTCCTTAGCTCTGAGGGAAA
TCCAACTTATTTGCGTAAGTGAATGTTCTCAGTTGGAACCTGCGTCATCACACAGGCCTGTTGG
ATGGTCCCAACATGTATGTGAGTGAACGTTCTCAGTCAGAACCTGCCTCATCCATCAGGCAGGC
CTGTTGGATGGTCTGTGTCATTGATCATACATCTGTTTCAGTCAAGTTGAGTCATGACCTGAGC
TTCAATTGATGTAGTTATCCGGGTACTTTTTCCCCCACACATTCCTTGAGCATCATCTCTCTGA
AAACTCAATGTTGCACCTACTAACTTGACGTTGACTAAATGAGCAATTCTGTGCCCATTAGTTT
CTTTCACAGTATGGAGGAGCAAAACCAGGACCTCGCACAGGCTA

hide sequence

RefSeq Acc Id:

XM_039085077 ⟹ XP_038941005

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,940,942 - 38,999,515 (+)	NCBI
mRatBN7.2	10	38,440,233 - 38,501,182 (+)	NCBI

RefSeq Acc Id:

XM_063268323 ⟹ XP_063124393

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,940,942 - 38,974,011 (+)	NCBI

RefSeq Acc Id:

XM_063268324 ⟹ XP_063124394

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	38,940,942 - 38,999,515 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001426476	(Get FASTA)	NCBI Sequence Viewer
	NP_001426477	(Get FASTA)	NCBI Sequence Viewer
	NP_001426478	(Get FASTA)	NCBI Sequence Viewer
	NP_001426479	(Get FASTA)	NCBI Sequence Viewer
	NP_001426480	(Get FASTA)	NCBI Sequence Viewer
	NP_001426481	(Get FASTA)	NCBI Sequence Viewer
	NP_001426482	(Get FASTA)	NCBI Sequence Viewer
	NP_001426483	(Get FASTA)	NCBI Sequence Viewer
	NP_001426484	(Get FASTA)	NCBI Sequence Viewer
	NP_001426485	(Get FASTA)	NCBI Sequence Viewer
	NP_570095	(Get FASTA)	NCBI Sequence Viewer
	XP_006246283	(Get FASTA)	NCBI Sequence Viewer
	XP_006246284	(Get FASTA)	NCBI Sequence Viewer
	XP_006246286	(Get FASTA)	NCBI Sequence Viewer
	XP_038941005	(Get FASTA)	NCBI Sequence Viewer
	XP_063124393	(Get FASTA)	NCBI Sequence Viewer
	XP_063124394	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB19809	(Get FASTA)	NCBI Sequence Viewer
	AAT41589	(Get FASTA)	NCBI Sequence Viewer
	ABS32032	(Get FASTA)	NCBI Sequence Viewer
	BAA00932	(Get FASTA)	NCBI Sequence Viewer
	CBF64987	(Get FASTA)	NCBI Sequence Viewer
	CBU89858	(Get FASTA)	NCBI Sequence Viewer
	EDM04428	(Get FASTA)	NCBI Sequence Viewer
	EDM04429	(Get FASTA)	NCBI Sequence Viewer
	EDM04430	(Get FASTA)	NCBI Sequence Viewer
	EDM04431	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000033248
	ENSRNOP00000033248.5
	ENSRNOP00000055608
	ENSRNOP00000081838
	ENSRNOP00000096136
GenBank Protein	P33124	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_570095 ⟸ NM_130739

- UniProtKB:

Q63835 (UniProtKB/Swiss-Prot), P33124 (UniProtKB/Swiss-Prot), Q6IU14 (UniProtKB/Swiss-Prot), A6HEH5 (UniProtKB/TrEMBL), A0A8I5ZSH7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQTQEILRILRLPELSDLGQFFRSLSATTLVSMGALAAILAYWLTHRPKALQPPCNLLMQSEEV
EDSGGARRSVIGDCTQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPEQPYQWLSYQEVAK
RAEFLGSGLLQHDCKVGTEQFIGVFAQNRPEWIIAELACYTYSMVVVPLYDTLGPGSIRYIINT
ADICTVIVDKPHKAILLLEHVERKETPGLKLVILMEPFDDALRERGKKCGVDIKSMQAIEDSGQ
ENHRVPVPPRPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHFSYL
PLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALRPTIFPVVPRLLNRMYDKIFHQADTS
LKRWLLEFAAKRKQAEVRSGIIRNNSIWDELFFNKIQASLGGHVRMIVTGAAPASPTVLGFLRA
ALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDAEELNYWTSKGEGEICVKG
PNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKDIFKLAQGEYVAPEKIENI
YIRSEPVAQIYVHGDSLKAFLVGIVVPDPEVMPCWAQKKGIEGNYQELCKSKELKKAILDDMVM
LGKESGLHSFEQVKAIYIHCDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSISM

hide sequence

RefSeq Acc Id:

XP_006246286 ⟸ XM_006246224

- Peptide Label:

isoform X4

- Sequence:

show sequence

MQTQEILRILRLPELSDLGQFFRSLSATTLVSMGALAAILAYWLTHRPKALQPPCNLLMQSEEV
EDSGGARRSVIGDCTQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPEQPYQWLSYQEVAK
RAEFLGSGLLQHDCKVGTEQFIGVFAQNRPEWIIAELACYTYSMVVVPLYDTLGPGSIRYIINT
ADICTVIVDKPHKAILLLEHVERKETPGLKLVILMEPFDDALRERGKKCGVDIKSMQAIEDSGQ
ENHRVPVPPRPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFL
PLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALRPTIFPVVPRLLNRMYDKIFHQADTS
LKRWLLEFAAKRKQAEVRSGIIRNNSIWDELFFNKIQASLGGHVRMIVTGAAPASPTVLGFLRA
ALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDAEELNYWTSKGEGEICVKG
PNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENI
YIRSEPVAQIYVHGDSLKAFLVGIVVPDPEVMPCWAQKKGIEGNYQELCKSKELKKAILDDMVM
LGKESGLHSFEQVKAIYIHCDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSISM

hide sequence

RefSeq Acc Id:

XP_006246283 ⟸ XM_006246221

- Peptide Label:

isoform X2

- Sequence:

show sequence

MPLSLCPGVPAALRGWESGSVRSARCALPLPPGLRSGAGRRGLKIPGGGGSGSGSGAAGLRAWE
AVRPGLGPLTDMLTFFLVSGGSLWLFAEIALSLLEKMQTQEILRILRLPELSDLGQFFRSLSAT
TLVSMGALAAILAYWLTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGDCTQLLTHYYDDARTM
YQVFRRGLSISGNGPCLGFRKPEQPYQWLSYQEVAKRAEFLGSGLLQHDCKVGTEQFIGVFAQN
RPEWIIAELACYTYSMVVVPLYDTLGPGSIRYIINTADICTVIVDKPHKAILLLEHVERKETPG
LKLVILMEPFDDALRERGKKCGVDIKSMQAIEDSGQENHRVPVPPRPDDLSIVCFTSGTTGNPK
GAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDI
RLLSDDMKALRPTIFPVVPRLLNRMYDKIFHQADTSLKRWLLEFAAKRKQAEVRSGIIRNNSIW
DELFFNKIQASLGGHVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWT
SGHVGAPLPCNHIKLVDAEELNYWTSKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGD
IGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAFLVGIVVPD
PEVMPCWAQKKGIEGNYQELCKSKELKKAILDDMVMLGKESGLHSFEQVKAIYIHCDMFSVQNG
LLTPTLKAKRPELREYFKKQIEELYSISM

hide sequence

RefSeq Acc Id:

XP_006246284 ⟸ XM_006246222

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPLSLCPGVPAALRGWESGSVRSARCALPLPPGLRSGAGRRGLKIPGGGGSGSGSGAAGLRAWE
AVRPGLGPLTDMLTFFLVSGGSLWLFAEIALSLLEKMQTQEILRILRLPELSDLGQFFRSLSAT
TLVSMGALAAILAYWLTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGDCTQLLTHYYDDARTM
YQVFRRGLSISGNGPCLGFRKPEQPYQWLSYQEVAKRAEFLGSGLLQHDCKVGTEQFIGVFAQN
RPEWIIAELACYTYSMVVVPLYDTLGPGSIRYIINTADICTVIVDKPHKAILLLEHVERKETPG
LKLVILMEPFDDALRERGKKCGVDIKSMQAIEDSGQENHRVPVPPRPDDLSIVCFTSGTTGNPK
GAMLTHGNVVADFSGFLKVTESQWAPTCADVHFSYLPLAHMFERMVQSVVYCHGGRVGFFQGDI
RLLSDDMKALRPTIFPVVPRLLNRMYDKIFHQADTSLKRWLLEFAAKRKQAEVRSGIIRNNSIW
DELFFNKIQASLGGHVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWT
SGHVGAPLPCNHIKLVDAEELNYWTSKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGD
IGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAFLVGIVVPD
PEVMPCWAQKKGIEGNYQELCKSKELKKAILDDMVMLGKESGLHSFEQVKAIYIHCDMFSVQNG
LLTPTLKAKRPELREYFKKQIEELYSISM

hide sequence

Ensembl Acc Id:

ENSRNOP00000055608 ⟸ ENSRNOT00000058817

Ensembl Acc Id:

ENSRNOP00000033248 ⟸ ENSRNOT00000030760

RefSeq Acc Id:	XP_038941005 ⟸ XM_039085077
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6B3S2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000080278 ⟸ ENSRNOT00000107770

Ensembl Acc Id:

ENSRNOP00000081838 ⟸ ENSRNOT00000115137

Ensembl Acc Id:

ENSRNOP00000096136 ⟸ ENSRNOT00000103397

RefSeq Acc Id:	XP_063124394 ⟸ XM_063268324
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6B3S2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063124393 ⟸ XM_063268323
- Peptide Label:	isoform X5

Protein Domains

AMP-dependent synthetase/ligase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P33124-F1-model_v2	AlphaFold	P33124	1-697	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697195

Promoter ID:

EPDNEW_R7712

Type:

single initiation site

Name:

Acsl6_1

Description:

acyl-CoA synthetase long-chain family member 6

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	39,655,427 - 39,655,487	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69403	AgrOrtholog
BioCyc Gene	G2FUF-25116	BioCyc
BioCyc Pathway	FAO-PWY [fatty acid beta-oxidation I (generic)]	BioCyc
	PWY-5143 [long-chain fatty acid activation]	BioCyc
	PWY-5972 [stearate biosynthesis I (animals)]	BioCyc
	PWY-6000 [gamma-linolenate biosynthesis II (animals)]	BioCyc
	PWY-7049 [icosapentaenoate biosynthesis II (6-desaturase, mammals)]	BioCyc
	PWY-8181 [2-methyl-branched fatty acid beta-oxidation]	BioCyc
	PWY3DJ-11470 [sphingosine and sphingosine-1-phosphate metabolism]	BioCyc
	PWY66-387 [3-methyl-branched fatty acid alpha-oxidation]	BioCyc
	PWY66-388 [ceramide degradation by alpha-oxidation]	BioCyc
	PWY66-389 [phytol degradation]	BioCyc
	PWY66-391 [fatty acid beta-oxidation VI (mammalian peroxisome)]	BioCyc
BioCyc Pathway Image	FAO-PWY	BioCyc
	PWY-5143	BioCyc
	PWY-5972	BioCyc
	PWY-6000	BioCyc
	PWY-7049	BioCyc
	PWY-8181	BioCyc
	PWY3DJ-11470	BioCyc
	PWY66-387	BioCyc
	PWY66-388	BioCyc
	PWY66-389	BioCyc
	PWY66-391	BioCyc
Ensembl Genes	ENSRNOG00000026745	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000030760	ENTREZGENE
	ENSRNOT00000030760.5	UniProtKB/Swiss-Prot
	ENSRNOT00000058817	ENTREZGENE
	ENSRNOT00000103397	ENTREZGENE
	ENSRNOT00000115137	ENTREZGENE
Gene3D-CATH	3.40.50.12780	UniProtKB/Swiss-Prot
InterPro	AMP-binding_CS	UniProtKB/Swiss-Prot
	AMP-dep_Synth/Lig	UniProtKB/Swiss-Prot
	ANL_N_sf	UniProtKB/Swiss-Prot
	LC-FACS_euk	UniProtKB/Swiss-Prot
KEGG Report	rno:117243	UniProtKB/Swiss-Prot
NCBI Gene	117243	ENTREZGENE
PANTHER	LONG-CHAIN-FATTY-ACID--COA LIGASE	UniProtKB/Swiss-Prot
	LONG-CHAIN-FATTY-ACID--COA LIGASE 6	UniProtKB/Swiss-Prot
Pfam	AMP-binding	UniProtKB/Swiss-Prot
PhenoGen	Acsl6	PhenoGen
PROSITE	AMP_BINDING	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000026745	RatGTEx
Superfamily-SCOP	Acetyl-CoA synthetase-like	UniProtKB/Swiss-Prot
TIGR	TC206202
UniProt	A0A0A6YYM0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZPS9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZSH7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6B3S2	ENTREZGENE, UniProtKB/TrEMBL
	A6HEH3_RAT	UniProtKB/TrEMBL
	A6HEH4_RAT	UniProtKB/TrEMBL
	A6HEH5	ENTREZGENE, UniProtKB/TrEMBL
	A6HEH6_RAT	UniProtKB/TrEMBL
	ACSL6_RAT	UniProtKB/Swiss-Prot
	B2BET9_RAT	UniProtKB/TrEMBL
	P33124	ENTREZGENE
	Q63835	ENTREZGENE
	Q6IU14	ENTREZGENE
UniProt Secondary	Q63835	UniProtKB/Swiss-Prot
	Q6IU14	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Acsl6	acyl-CoA synthetase long-chain family member 6	Facl6	fatty acid Coenzyme A ligase, long chain 6	Symbol and Name updated	1299863	APPROVED
2002-06-10	Facl6	fatty acid Coenzyme A ligase, long chain 6			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	highly expressed in intestine; also present in liver	69376
gene_expression	mRNAs increases in liver by high sucrose refeeding and decreases with fasting	69376
gene_function	catalyzes the ligation of long chain fatty acids with coenzyme A to produce long chain acyl-CoAs, has a broad substrate specificity for saturated fatty acids of 1218 carbon atoms and unsaturated fatty acids of 1620 carbon atoms	69376
gene_process	involved in energy use via b-oxidation and the synthesis of triacylglycerol, phospholipids, cholesterol esters, and sphingomyelin	69376

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

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InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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