Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Glg1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Glg1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of GLG1 mRNA] | CTD | PMID:22206623 | Glg1 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of GLG1 mRNA | CTD | PMID:22206623 | Glg1 | Rat | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | decreases expression | ISO | Glg1 (Mus musculus) | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:15329391 | Glg1 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Glg1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of GLG1 mRNA | CTD | PMID:17555576 | Glg1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Glg1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GLG1 mRNA | CTD | PMID:17942748 | Glg1 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of GLG1 mRNA | CTD | PMID:17942748 | Glg1 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of GLG1 mRNA | CTD | PMID:32145629 | Glg1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Glg1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GLG1 mRNA | CTD | PMID:17942748 | Glg1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GLG1 mRNA | CTD | PMID:33387578 | Glg1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Glg1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GLG1 mRNA | CTD | PMID:21570461 | Glg1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of GLG1 mRNA | CTD | PMID:22298810 | Glg1 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of GLG1 mRNA | CTD | PMID:21346803 | Glg1 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of GLG1 mRNA | CTD | PMID:30851411 | Glg1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of GLG1 protein | CTD | PMID:34186270 | Glg1 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of GLG1 mRNA | CTD | PMID:30047161 | Glg1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of GLG1 mRNA | CTD | PMID:36843608 | Glg1 | Rat | acetazolamide | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | Acetazolamide results in increased expression of GLG1 mRNA | CTD | PMID:19274763 | Glg1 | Rat | acrolein | multiple interactions | ISO | GLG1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of GLG1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of GLG1 mRNA | CTD | PMID:32699268 | Glg1 | Rat | acrylamide | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of GLG1 mRNA | CTD | PMID:32763439 | Glg1 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | GLG1 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of GLG1 intron | CTD | PMID:30157460 | Glg1 | Rat | alpha-pinene | multiple interactions | ISO | GLG1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of GLG1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of GLG1 mRNA | CTD | PMID:32699268 | Glg1 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of GLG1 mRNA | CTD | PMID:30047161 | Glg1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of GLG1 mRNA | CTD | PMID:16483693 | Glg1 | Rat | aristolochic acid A | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of GLG1 mRNA | CTD | PMID:33212167 | Glg1 | Rat | Aroclor 1254 | decreases expression | ISO | Glg1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of GLG1 mRNA | CTD | PMID:23650126 | Glg1 | Rat | benzo[a]pyrene | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of GLG1 mRNA | CTD | PMID:22228805 | Glg1 | Rat | benzo[a]pyrene | affects methylation | ISO | GLG1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of GLG1 intron | CTD | PMID:30157460 | Glg1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of GLG1 mRNA | CTD | PMID:25181051 | Glg1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GLG1 mRNA | CTD | PMID:30816183 more ... | Glg1 | Rat | bisphenol A | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of GLG1 mRNA and bisphenol A results in increased expression of GLG1 protein | CTD | PMID:29275510 more ... | Glg1 | Rat | Bisphenol B | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of GLG1 protein | CTD | PMID:34186270 | Glg1 | Rat | bisphenol F | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of GLG1 mRNA | CTD | PMID:38685157 | Glg1 | Rat | bisphenol F | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of GLG1 protein | CTD | PMID:34186270 | Glg1 | Rat | butanal | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of GLG1 mRNA | CTD | PMID:26079696 | Glg1 | Rat | cadmium dichloride | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | Cadmium Chloride results in increased expression of GLG1 mRNA | CTD | PMID:20883709 | Glg1 | Rat | cadmium dichloride | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of GLG1 mRNA | CTD | PMID:26472689 | Glg1 | Rat | cadmium dichloride | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of GLG1 protein | CTD | PMID:24527689 | Glg1 | Rat | CGP 52608 | multiple interactions | ISO | GLG1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GLG1 gene] | CTD | PMID:28238834 | Glg1 | Rat | chloropicrin | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | chloropicrin results in increased expression of GLG1 mRNA | CTD | PMID:26352163 | Glg1 | Rat | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of GLG1 mRNA | CTD | PMID:18668222 | Glg1 | Rat | chlorpyrifos | decreases expression | ISO | Glg1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of GLG1 mRNA | CTD | PMID:37019170 | Glg1 | Rat | choline | multiple interactions | ISO | Glg1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GLG1 gene | CTD | PMID:20938992 | Glg1 | Rat | copper atom | multiple interactions | ISO | GLG1 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of GLG1 mRNA | CTD | PMID:24690739 | Glg1 | Rat | copper(0) | multiple interactions | ISO | GLG1 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of GLG1 mRNA | CTD | PMID:24690739 | Glg1 | Rat | cyclosporin A | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of GLG1 mRNA | CTD | PMID:27989131 | Glg1 | Rat | Dibutyl phosphate | affects expression | ISO | GLG1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of GLG1 mRNA | CTD | PMID:37042841 | Glg1 | Rat | disodium selenite | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of GLG1 mRNA | CTD | PMID:18175754 | Glg1 | Rat | disulfiram | multiple interactions | ISO | GLG1 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of GLG1 mRNA | CTD | PMID:24690739 | Glg1 | Rat | doxorubicin | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of GLG1 mRNA | CTD | PMID:29803840 | Glg1 | Rat | elemental selenium | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Selenium results in decreased expression of GLG1 mRNA | CTD | PMID:19244175 | Glg1 | Rat | elemental selenium | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Selenium results in increased expression of GLG1 mRNA | CTD | PMID:19244175 | Glg1 | Rat | ethanol | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | Ethanol results in increased expression of GLG1 mRNA | CTD | PMID:30319688 | Glg1 | Rat | fenthion | decreases expression | ISO | Glg1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of GLG1 mRNA | CTD | PMID:34813904 | Glg1 | Rat | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of GLG1 mRNA | CTD | PMID:34044035 | Glg1 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of GLG1 mRNA | CTD | PMID:24136188 | Glg1 | Rat | folic acid | multiple interactions | ISO | Glg1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GLG1 gene more ... | CTD | PMID:20938992 and PMID:22206623 | Glg1 | Rat | genistein | increases methylation | EXP | | 6480464 | Genistein results in increased methylation of GLG1 gene | CTD | PMID:28505145 | Glg1 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of GLG1 mRNA | CTD | PMID:33387578 | Glg1 | Rat | hexachlorobenzene | affects expression | EXP | | 6480464 | Hexachlorobenzene affects the expression of GLG1 mRNA | CTD | PMID:15159207 | Glg1 | Rat | isoprenaline | multiple interactions | EXP | | 6480464 | [Isoproterenol co-treated with POSTN protein] results in decreased expression of GLG1 mRNA | CTD | PMID:30303030 | Glg1 | Rat | ivermectin | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of GLG1 protein | CTD | PMID:32959892 | Glg1 | Rat | L-methionine | multiple interactions | ISO | Glg1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GLG1 gene | CTD | PMID:20938992 | Glg1 | Rat | linsidomine | increases oxidation | EXP | | 6480464 | linsidomine results in increased oxidation of GLG1 protein | CTD | PMID:28086193 | Glg1 | Rat | menadione | affects expression | ISO | GLG1 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of GLG1 mRNA | CTD | PMID:20044591 | Glg1 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of GLG1 mRNA | CTD | PMID:30047161 | Glg1 | Rat | ozone | multiple interactions | ISO | GLG1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of GLG1 mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | Glg1 | Rat | paracetamol | affects expression | ISO | Glg1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of GLG1 mRNA | CTD | PMID:17562736 | Glg1 | Rat | pentachlorophenol | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of GLG1 mRNA | CTD | PMID:23892564 | Glg1 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Glg1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of GLG1 mRNA | CTD | PMID:37995155 | Glg1 | Rat | perfluorooctanoic acid | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of GLG1 protein | CTD | PMID:26879310 | Glg1 | Rat | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of GLG1 protein | CTD | PMID:34958885 | Glg1 | Rat | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of GLG1 mRNA | CTD | PMID:30047161 | Glg1 | Rat | pirinixic acid | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of GLG1 mRNA | CTD | PMID:18301758 | Glg1 | Rat | potassium dichromate | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Potassium Dichromate results in decreased expression of GLG1 protein | CTD | PMID:23718831 | Glg1 | Rat | propiconazole | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | propiconazole results in increased expression of GLG1 mRNA | CTD | PMID:21278054 | Glg1 | Rat | rac-lactic acid | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of GLG1 mRNA | CTD | PMID:30851411 | Glg1 | Rat | selenium atom | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Selenium results in decreased expression of GLG1 mRNA | CTD | PMID:19244175 | Glg1 | Rat | selenium atom | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Selenium results in increased expression of GLG1 mRNA | CTD | PMID:19244175 | Glg1 | Rat | sodium arsenite | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of GLG1 mRNA | CTD | PMID:20883709 | Glg1 | Rat | succimer | multiple interactions | ISO | GLG1 (Homo sapiens) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of GLG1 mRNA | CTD | PMID:26378955 | Glg1 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of GLG1 mRNA | CTD | PMID:30047161 | Glg1 | Rat | tamoxifen | affects expression | ISO | Glg1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of GLG1 mRNA | CTD | PMID:17555576 | Glg1 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of GLG1 mRNA | CTD | PMID:15336504 | Glg1 | Rat | testosterone enanthate | affects expression | ISO | GLG1 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of GLG1 mRNA | CTD | PMID:17440010 | Glg1 | Rat | thapsigargin | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | Thapsigargin results in increased expression of GLG1 protein | CTD | PMID:24648495 | Glg1 | Rat | thapsigargin | decreases expression | EXP | | 6480464 | Thapsigargin results in decreased expression of GLG1 protein | CTD | PMID:35544339 | Glg1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of GLG1 mRNA | CTD | PMID:23411599 | Glg1 | Rat | thiram | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Thiram results in decreased expression of GLG1 mRNA | CTD | PMID:38568856 | Glg1 | Rat | titanium dioxide | decreases expression | ISO | Glg1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of GLG1 mRNA | CTD | PMID:27760801 | Glg1 | Rat | titanium dioxide | increases methylation | ISO | Glg1 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of GLG1 gene | CTD | PMID:35295148 | Glg1 | Rat | titanium dioxide | decreases methylation | ISO | Glg1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of GLG1 gene | CTD | PMID:35295148 | Glg1 | Rat | tolcapone | affects binding | EXP | | 6480464 | tolcapone binds to GLG1 protein | CTD | PMID:19783845 | Glg1 | Rat | triphenyl phosphate | affects expression | ISO | GLG1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of GLG1 mRNA | CTD | PMID:37042841 | Glg1 | Rat | troglitazone | decreases expression | ISO | Glg1 (Mus musculus) | 6480464 | troglitazone results in decreased expression of GLG1 mRNA | CTD | PMID:28973697 | Glg1 | Rat | tungsten | decreases expression | ISO | Glg1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of GLG1 mRNA | CTD | PMID:30912803 | Glg1 | Rat | valproic acid | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GLG1 mRNA and Valproic Acid results in increased expression of GLG1 protein | CTD | PMID:29501571 | Glg1 | Rat | valproic acid | increases methylation | ISO | GLG1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of GLG1 gene | CTD | PMID:29501571 | Glg1 | Rat | vitamin E | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of GLG1 mRNA | CTD | PMID:19244175 | Glg1 | Rat | vitamin E | increases expression | ISO | GLG1 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of GLG1 mRNA | CTD | PMID:19244175 | Glg1 | Rat | vorinostat | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of GLG1 mRNA | CTD | PMID:27188386 | Glg1 | Rat | zearalenone | increases expression | ISO | Glg1 (Mus musculus) | 6480464 | Zearalenone results in increased expression of GLG1 protein | CTD | PMID:36252740 | Glg1 | Rat | zoledronic acid | decreases expression | ISO | GLG1 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of GLG1 mRNA | CTD | PMID:20977926 | |