Prg2 (proteoglycan 2, pro eosinophil major basic protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Prg2 (proteoglycan 2, pro eosinophil major basic protein) Rattus norvegicus
Analyze
Symbol: Prg2
Name: proteoglycan 2, pro eosinophil major basic protein
RGD ID: 69336
Description: Predicted to enable heparin binding activity. Predicted to be involved in defense response to bacterium and immune response. Predicted to act upstream of or within defense response to nematode and regulation of cytokine production. Predicted to be located in extracellular region. Orthologous to human PRG2 (proteoglycan 2, pro eosinophil major basic protein); PARTICIPATES IN asthma pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BMPG; bone marrow proteoglycan; eosinophil major basic protein; proteoglycan 2; proteoglycan 2, bone marrow
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,469,192 - 90,472,759 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl390,469,176 - 90,472,752 (+)EnsemblGRCr8
mRatBN7.2370,062,535 - 70,066,102 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl370,062,535 - 70,066,101 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx373,444,448 - 73,448,007 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0382,043,123 - 82,046,682 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,801,564 - 79,805,137 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,385,678 - 72,389,245 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,385,666 - 72,389,276 (+)Ensemblrn6Rnor6.0
Rnor_5.0378,895,715 - 78,899,282 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4368,209,731 - 68,213,293 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera369,413,529 - 69,417,096 (+)NCBICelera
RGSC_v3.1368,106,102 - 68,109,669 (+)NCBI
Cytogenetic Map3q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Eosinophils are important for protection, immunoregulation and pathology during infection with nematode microfilariae. Cadman ET, etal., PLoS Pathog. 2014 Mar 13;10(3):e1003988. doi: 10.1371/journal.ppat.1003988. eCollection 2014 Mar.
2. Eosinophil major basic protein-1 does not contribute to allergen-induced airway pathologies in mouse models of asthma. Denzler KL, etal., J Immunol. 2000 Nov 15;165(10):5509-17.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Alterations in Placental Gene Expression of Pregnant Women with Chronic Chagas Disease. Juiz NA, etal., Am J Pathol. 2018 Jun;188(6):1345-1353. doi: 10.1016/j.ajpath.2018.02.011. Epub 2018 Mar 12.
5. Eosinophil degranulation is more important than eosinophilia in identifying asthma in chronic cough. Kim CK, etal., J Asthma. 2011 Dec;48(10):994-1000. doi: 10.3109/02770903.2011.623335. Epub 2011 Oct 24.
6. [Expression of eosinophil major basic protein mRNA in bronchial asthma]. Li SH, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2006 Sep;26(9):1330-3.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Cloning of cDNA for rat eosinophil major basic protein. Nittoh T, etal., Biochim Biophys Acta 1995 Dec 27;1264(3):261-4.
10. Corrigendum to "Cloning of cDNA for rat eosinophil major basic protein" [Biochim. Biophys. Acta 1264 (1995) 261-264] Nittoh T, etal., Biochim Biophys Acta 1996 Apr 10;1306(1):115-6.
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. GOA pipeline RGD automated data pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Interferon gene expression in sputum cells correlates with the Asthma Index Score during virus-induced exacerbations. Schwantes EA, etal., Clin Exp Allergy. 2014 Jun;44(6):813-21. doi: 10.1111/cea.12269.
15. Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells. Seebauer CT, etal., Oncoimmunology. 2016 Oct 14;5(12):e1242543. doi: 10.1080/2162402X.2016.1242543. eCollection 2016.
16. Crystal structure of the eosinophil major basic protein at 1.8 A. An atypical lectin with a paradigm shift in specificity. Swaminathan GJ, etal., J Biol Chem 2001 Jul 13;276(28):26197-203. Epub 2001 Apr 23.
Additional References at PubMed
PMID:8889548   PMID:16926417   PMID:18178677   PMID:22206666   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Prg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,469,192 - 90,472,759 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl390,469,176 - 90,472,752 (+)EnsemblGRCr8
mRatBN7.2370,062,535 - 70,066,102 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl370,062,535 - 70,066,101 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx373,444,448 - 73,448,007 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0382,043,123 - 82,046,682 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,801,564 - 79,805,137 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,385,678 - 72,389,245 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,385,666 - 72,389,276 (+)Ensemblrn6Rnor6.0
Rnor_5.0378,895,715 - 78,899,282 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4368,209,731 - 68,213,293 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera369,413,529 - 69,417,096 (+)NCBICelera
RGSC_v3.1368,106,102 - 68,109,669 (+)NCBI
Cytogenetic Map3q24NCBI
PRG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,386,780 - 57,390,650 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,386,780 - 57,391,143 (-)Ensemblhg38GRCh38
GRCh371157,154,253 - 57,158,123 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,911,410 - 56,914,706 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341156,911,410 - 56,914,706NCBI
Celera1154,511,420 - 54,514,715 (-)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1153,504,113 - 53,507,408 (-)NCBIHuRef
CHM1_11157,020,853 - 57,024,149 (-)NCBICHM1_1
T2T-CHM13v2.01157,336,805 - 57,340,674 (-)NCBIT2T-CHM13v2.0
Prg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,810,805 - 84,813,977 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl284,810,805 - 84,813,976 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38284,980,461 - 84,983,632 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,980,461 - 84,983,632 (+)Ensemblmm10GRCm38
MGSCv37284,820,618 - 84,823,789 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36284,781,300 - 84,784,471 (+)NCBIMGSCv36mm8
Celera286,579,143 - 86,582,324 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.45NCBI
PRG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2958,543,286 - 58,547,177 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,560,838 - 59,564,163 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01152,628,289 - 52,631,634 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13160,118,686 - 160,122,041 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3160,118,111 - 160,122,002 (-)EnsemblpanPan2panpan1.1
LOC102156778
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,753,269 - 38,760,730 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,303,196 - 38,306,317 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01839,438,926 - 39,442,046 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11839,021,552 - 39,024,671 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01838,595,057 - 38,598,175 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01839,225,795 - 39,228,916 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Prg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494714,987,025 - 14,989,758 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365815,100,623 - 5,102,857 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365815,101,041 - 5,103,175 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1115,850,181 - 15,854,511 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl115,850,913 - 15,854,517 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038113,195,782 - 113,199,106 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prg2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1562,348,493 - 62,351,507 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Prg2
11 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:104
Count of miRNA genes:87
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000011168
Prediction methods:Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)35365182698651826Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)34887661993876619Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)34887661993876619Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)34790417292904172Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35109256196092561Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)34865774493657744Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)358925062103925062Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)34865774493657744Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)35076614595766145Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)35109256196092561Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)35076614595766145Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)34865774493657744Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)34865774493657744Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)34865774493657744Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 9 46 126 76 78 49 71 49 3 257 140 11 105 49 46 29 6 6

Sequence


Ensembl Acc Id: ENSRNOT00000011168   ⟹   ENSRNOP00000011168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl390,469,176 - 90,472,752 (+)Ensembl
mRatBN7.2 Ensembl370,062,535 - 70,066,101 (+)Ensembl
Rnor_6.0 Ensembl372,385,666 - 72,389,276 (+)Ensembl
RefSeq Acc Id: NM_031619   ⟹   NP_113807
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,469,192 - 90,472,759 (+)NCBI
mRatBN7.2370,062,535 - 70,066,102 (+)NCBI
Rnor_6.0372,385,678 - 72,389,245 (+)NCBI
Rnor_5.0378,895,715 - 78,899,282 (+)NCBI
RGSC_v3.4368,209,731 - 68,213,293 (+)RGD
Celera369,413,529 - 69,417,096 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_113807 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA09129 (Get FASTA)   NCBI Sequence Viewer  
  EDL79326 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011168
GenBank Protein Q63189 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113807   ⟸   NM_031619
- Peptide Label: precursor
- UniProtKB: Q63189 (UniProtKB/Swiss-Prot),   G3V729 (UniProtKB/TrEMBL),   A6HMS5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011168   ⟸   ENSRNOT00000011168
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63189-F1-model_v2 AlphaFold Q63189 1-227 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692188
Promoter ID:EPDNEW_R2713
Type:single initiation site
Name:Prg2_1
Description:proteoglycan 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0372,385,665 - 72,385,725EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69336 AgrOrtholog
BioCyc Gene G2FUF-49142 BioCyc
Ensembl Genes ENSRNOG00000008394 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000011168 ENTREZGENE
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot
InterPro C-type_lectin-like UniProtKB/Swiss-Prot
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot
  C-type_lectin/snaclec_domain UniProtKB/Swiss-Prot
  C-type_lectin_CS UniProtKB/Swiss-Prot
  CTDL_fold UniProtKB/Swiss-Prot
  EMBP_CTLD UniProtKB/Swiss-Prot
  Eosinophil_major_basic UniProtKB/Swiss-Prot
KEGG Report rno:58826 UniProtKB/Swiss-Prot
NCBI Gene 58826 ENTREZGENE
PANTHER MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED UniProtKB/Swiss-Prot
Pfam Lectin_C UniProtKB/Swiss-Prot
PhenoGen Prg2 PhenoGen
PRINTS EMAJORBASICP UniProtKB/Swiss-Prot
PROSITE C_TYPE_LECTIN_1 UniProtKB/Swiss-Prot
  C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008394 RatGTEx
SMART CLECT UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot
UniProt A6HMS5 ENTREZGENE, UniProtKB/TrEMBL
  G3V729 ENTREZGENE, UniProtKB/TrEMBL
  PRG2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-09-30 Prg2  proteoglycan 2, pro eosinophil major basic protein  Prg2  proteoglycan 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-03-16 Prg2  proteoglycan 2  Prg2  proteoglycan 2, bone marrow  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Prg2  proteoglycan 2, bone marrow      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference