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Gene: Gtf2a1 (general transcription factor 2A subunit 1) Rattus norvegicus

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Symbol:

Gtf2a1

Name:

general transcription factor 2A subunit 1

RGD ID:

69246

Description:

Predicted to enable several functions, including RNA polymerase II core promoter sequence-specific DNA binding activity; RNA polymerase II general transcription initiation factor activity; and general transcription initiation factor binding activity. Predicted to be involved in positive regulation of transcription initiation by RNA polymerase II and transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription factor TFIIA complex; transcription factor TFIID complex; and transcription preinitiation complex. Orthologous to human GTF2A1 (general transcription factor IIA subunit 1); PARTICIPATES IN RNA polymerase II transcription initiation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

general transcription factor 2a, 1; general transcription factor II A, 1; general transcription factor IIa 1 (37kD and 19kD subunits); general transcription factor IIA subunit 1; general transcription factor IIA, 1; general transcription factor IIa, 1 (37kD and 19kD subunits); Tf2a; TfIIa; TFIIA large subunit; transcription initiation factor IIA subunit 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GTF2A1 (general transcription factor IIA subunit 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Gtf2a1 (general transcription factor II A, 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gtf2a1 (general transcription factor IIA subunit 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GTF2A1 (general transcription factor IIA subunit 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GTF2A1 (general transcription factor IIA subunit 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gtf2a1 (general transcription factor IIA subunit 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GTF2A1 (general transcription factor IIA subunit 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GTF2A1 (general transcription factor IIA subunit 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gtf2a1 (general transcription factor IIA subunit 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Gtf2a1 (general transcription factor IIA subunit 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GTF2A1L (general transcription factor IIA subunit 1 like)	HGNC	Treefam
Homo sapiens (human):	ASB7 (ankyrin repeat and SOCS box containing 7)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	GTF2A1 (general transcription factor IIA subunit 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gtf2a1 (general transcription factor II A, 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gtf2a1 (general transcription factor IIA, 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TOA1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	TfIIA-L	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	TfIIA-L	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pqn-51	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	pqn-51	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	gtf2a1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	116,219,614 - 116,252,220 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	116,219,614 - 116,252,220 (-)	Ensembl				GRCr8
mRatBN7.2	6	110,488,891 - 110,521,502 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	110,488,931 - 110,521,511 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	110,632,610 - 110,660,371 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	110,931,266 - 110,959,022 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	110,305,967 - 110,333,614 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	115,321,110 - 115,352,659 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	115,320,467 - 115,352,681 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	124,576,129 - 124,607,638 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	115,180,871 - 115,210,825 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	108,243,380 - 108,271,421 (-)	NCBI		Celera
RGSC_v3.1	6	115,184,401 - 115,214,356 (-)	NCBI
Cytogenetic Map	6	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Dandy-Walker syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2-hydroxypropanoic acid (ISO)

2-methoxyethanol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrylamide (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

copper(II) sulfate (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

enzyme inhibitor (ISO)

folic acid (ISO)

geldanamycin (ISO)

gemcitabine (ISO)

gentamycin (EXP)

indometacin (ISO)

isoprenaline (ISO)

ivermectin (ISO)

okadaic acid (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

thimerosal (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

DNA-templated transcription (IEA)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of transcription initiation by RNA polymerase II (IEA,ISO)

transcription by RNA polymerase II (IBA,IEA,ISO)

transcription initiation at RNA polymerase II promoter (IEA)

Cellular Component

cytoplasm (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

transcription factor TFIIA complex (IBA,IEA,ISO)

transcription factor TFIID complex (IEA,ISO)

transcription preinitiation complex (IEA,ISO)

Molecular Function

DNA binding (IEA,ISO)

protein binding (ISO)

protein heterodimerization activity (IEA,ISO)

RNA polymerase II core promoter sequence-specific DNA binding (IEA,ISO)

RNA polymerase II general transcription initiation factor activity (IEA,ISO)

RNA polymerase II general transcription initiation factor binding (IEA,ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (IEA,ISO)

TBP-class protein binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase II transcription initiation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Structural insights into transcription initiation by RNA polymerase II.	Grunberg S and Hahn S, Trends Biochem Sci. 2013 Dec;38(12):603-11. doi: 10.1016/j.tibs.2013.09.002. Epub 2013 Oct 11.
4.	Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription.	Ma D, etal., Genes Dev 1993 Nov;7(11):2246-57.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	GOA pipeline	RGD automated data pipeline
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:7724559	PMID:7958900	PMID:8626665	PMID:11159353	PMID:15927180	PMID:19235719	PMID:27193682

Genomics

Comparative Map Data

Gtf2a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	116,219,614 - 116,252,220 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	116,219,614 - 116,252,220 (-)	Ensembl				GRCr8
mRatBN7.2	6	110,488,891 - 110,521,502 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	110,488,931 - 110,521,511 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	110,632,610 - 110,660,371 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	110,931,266 - 110,959,022 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	110,305,967 - 110,333,614 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	115,321,110 - 115,352,659 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	115,320,467 - 115,352,681 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	124,576,129 - 124,607,638 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	115,180,871 - 115,210,825 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	108,243,380 - 108,271,421 (-)	NCBI		Celera
RGSC_v3.1	6	115,184,401 - 115,214,356 (-)	NCBI
Cytogenetic Map	6	q31	NCBI

GTF2A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	81,175,452 - 81,221,390 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	81,175,452 - 81,221,377 (-)	Ensembl			hg38	GRCh38
GRCh37	14	81,641,796 - 81,687,734 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	80,716,147 - 80,757,328 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	80,716,146 - 80,757,328	NCBI
Celera	14	61,686,296 - 61,727,496 (-)	NCBI		Celera
Cytogenetic Map	14	q31.1	NCBI
HuRef	14	61,809,402 - 61,855,401 (-)	NCBI		HuRef
CHM1_1	14	81,582,217 - 81,627,845 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	75,387,683 - 75,433,560 (-)	NCBI		T2T-CHM13v2.0

Gtf2a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	91,522,036 - 91,559,102 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	91,522,036 - 91,557,261 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	12	91,555,262 - 91,590,487 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	91,555,262 - 91,590,487 (-)	Ensembl			mm10	GRCm38
MGSCv37	12	92,793,702 - 92,828,927 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	12	91,964,272 - 91,996,044 (-)	NCBI		MGSCv36	mm8
Celera	12	92,856,544 - 92,892,065 (-)	NCBI		Celera
Cytogenetic Map	12	D3	NCBI
cM Map	12	45.02	NCBI

Gtf2a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	4,787,190 - 4,825,577 (-)	Ensembl
ChiLan1.0	NW_004955438	4,787,190 - 4,825,578 (-)	NCBI	ChiLan1.0	ChiLan1.0

GTF2A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	82,285,120 - 82,330,430 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	81,501,625 - 81,546,928 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	61,751,492 - 61,797,083 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	80,951,886 - 80,996,777 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	80,951,886 - 80,996,777 (-)	Ensembl			panPan2	panpan1.1

GTF2A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	53,520,740 - 53,568,888 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	53,524,787 - 53,568,705 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	53,078,908 - 53,125,623 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	53,750,721 - 53,797,167 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	53,750,104 - 53,797,236 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	53,432,356 - 53,478,683 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	53,436,154 - 53,482,553 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	53,828,585 - 53,875,047 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gtf2a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	22,433,469 - 22,472,544 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	9,600,465 - 9,630,310 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	9,595,344 - 9,630,357 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GTF2A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	103,963,248 - 104,009,226 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	103,963,863 - 104,009,318 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	109,961,234 - 109,992,442 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GTF2A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	58,506,888 - 58,552,587 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	58,506,537 - 58,551,069 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666053	46,230,975 - 46,277,956 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gtf2a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	20,795,474 - 20,831,234 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624734	20,795,550 - 20,830,602 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gtf2a1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	104,695,574 - 104,728,050 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Gtf2a1
220 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	11
Count of miRNA genes:	10
Interacting mature miRNAs:	11
Transcripts:	ENSRNOT00000005873
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	71278722	116278722	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	112483610	147156653	Rat
1331797	Bp213	Blood pressure QTL 213	3.291		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	114241077	147156653	Rat
2293088	Iddm28	Insulin dependent diabetes mellitus QTL 28	5.21		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	68767270	135411972	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	88019181	136741135	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	90871046	135871046	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	93560258	136550638	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	98944780	143944780	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	100704576	136029228	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	110921244	147156653	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	79198463	144254945	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	106095977	147156653	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	46050607	116278722	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	93778632	138778632	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	84490437	129490437	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	90871046	135871046	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	93560258	136550638	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	101593607	138161926	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	78204640	123204640	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	93560258	136550638	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	76937178	121937178	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	99437079	125323237	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	101593607	146593607	Rat

Markers in Region

RH138870

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	110,516,235 - 110,516,387 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	115,347,706 - 115,347,857	NCBI	Rnor6.0
Rnor_5.0	6	124,602,685 - 124,602,836	UniSTS	Rnor5.0
RGSC_v3.4	6	115,205,430 - 115,205,581	UniSTS	RGSC3.4
Celera	6	108,266,754 - 108,266,905	UniSTS
RH 3.4 Map	6	757.1	UniSTS
Cytogenetic Map	6	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039113000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF000943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000005873 ⟹ ENSRNOP00000005873

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	116,219,614 - 116,251,833 (-)	Ensembl
mRatBN7.2 Ensembl	6	110,488,931 - 110,521,128 (-)	Ensembl
Rnor_6.0 Ensembl	6	115,320,467 - 115,352,681 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104002 ⟹ ENSRNOP00000086237

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	116,219,614 - 116,249,917 (-)	Ensembl
mRatBN7.2 Ensembl	6	110,488,931 - 110,519,199 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119546 ⟹ ENSRNOP00000091168

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	116,219,614 - 116,252,220 (-)	Ensembl
mRatBN7.2 Ensembl	6	110,488,931 - 110,521,511 (-)	Ensembl

RefSeq Acc Id:

NM_022208 ⟹ NP_071544

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	116,219,614 - 116,252,220 (-)	NCBI
mRatBN7.2	6	110,488,891 - 110,521,502 (-)	NCBI
Rnor_6.0	6	115,324,880 - 115,352,659 (-)	NCBI
Rnor_5.0	6	124,576,129 - 124,607,638 (-)	NCBI
RGSC_v3.4	6	115,180,871 - 115,210,825 (-)	RGD
Celera	6	108,243,380 - 108,271,421 (-)	RGD

Sequence:

show sequence

ATGGCGAACTCGGCAAACACAAACACCGTGCCTAAATTGTATAGATCTGTGATTGAAGATGTTA
TTAATGATGTCCGAGACATTTTTCTGGATGATGGAGTGGATGAACAGGTCCTGATGGAACTAAA
AACTTTGTGGGAGAATAAACTAATGCAGTCTAGGGCAGTAGATGGATTTCATTCAGAAGAACAG
CAGCTTTTGTTGCAAGTTCAGCAGCAGCACCAGCCCCAGCAGCAGCAGCATCACCACCACCACC
ACCACCAGCAGGCGCAACCTCAGCAAACGGTACCTCAGCAAGCACAGACCCAGCAGGTTCTTAT
TCCTGCGTCACAGCAAGCTACAGCACCACAAGTTATTGTTCCTGATTCTAAGTTGATACAACAT
ATGAATGCATCAAGTATTACGAGTGCTGCTGCTACAGCTGCTACCTTGGCGCTCCCTGCAGGCG
TGACTCCTGTTCAGCAGATACTAACAAATTCAGGCCAGCTGCTTCAGGTAGTCAGAGCAGCCAA
TGGTGCCCAATATATCTTTCAGCCTCAGCAGTCAGTTGTTCTACAACAACAAGTTATACCACAA
ATGCAGCCTGGTGGAGTACAAGCGCCTGTTATCCAGCAGGTCCTAGCCCCACTTCCTGGAGGGA
TTTCACCACAGACCGGTGTCATCATCCAGCCACAGCAAATCTTATTTACAGGGAATAAGACTCA
GGTCATTCCTACGACAGTGGCAGCGCCCACACCAGCACAAGCACAGATCCCTGCAGCTGGACAG
CAGCAGCCACAGGCCCAGCCTGCTCAGCAGCAGGCTCCATTGGTGCTGCAAGTTGACGGAACAG
GGGACACATCTTCTGAGGAAGATGAAGACGAAGAAGAAGACTATGATGATGATGAAGAGGAAGA
TAAAGAGAAAGATGGAGCCGAAGATGGGCAGGTGGAAGAAGAGCCCCTCAACAGCGAAGATGAT
GTAAGTGATGAGGAAGGGCAGGAACTCTTTGACACAGAAAATGTTGTTGTATGCCAGTATGATA
AGATACACAGAAGTAAAAATAAATGGAAATTTCATCTCAAGGATGGCATTATGAATCTTAATGG
AAGAGATTATATATTTTCCAAAGCCATTGGAGATGCAGAGTGGTGA

hide sequence

RefSeq Acc Id:

XM_006240410 ⟹ XP_006240472

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	116,219,614 - 116,251,704 (-)	NCBI
mRatBN7.2	6	110,488,891 - 110,520,984 (-)	NCBI
Rnor_6.0	6	115,321,110 - 115,352,221 (-)	NCBI
Rnor_5.0	6	124,576,129 - 124,607,638 (-)	NCBI

Sequence:

show sequence

GCGGGACCCGGACCCGGCCAGCCTCCCGAGCGTCCGCGGGTCGAGCCCCGCGTTTGGGGAGCCT
CTTGGACGTCGCCAAGGCCGGGCGTGCCTTCGGGGGCTCTCTGGAGGTGGTGCTTTGGGAAGCC
TCCGCTGGGGCCGATTTTACTAATCCTCCGAAAGGAAAAAAAAAAAAAGAGACAAAAAAGATGA
AGGTTGGAAAGCACTTATCTCGGTTCCTCCCCAGTGGATAAAATGGCGAAGGGGAAGCAAAACC
CCCGCGGTATCCTCGACTAGCAAAAGCACCAGAACAAACAAAGCCTACACCTAAATTGTATAGA
TCTGTGATTGAAGATGTTATTAATGATGTCCGAGACATTTTTCTGGATGATGGAGTGGATGAAC
AGGTCCTGATGGAACTAAAAACTTTGTGGGAGAATAAACTAATGCAGTCTAGGGCAGTAGATGG
ATTTCATTCAGAAGAACAGCAGCTTTTGTTGCAAGTTCAGCAGCAGCACCAGCCCCAGCAGCAG
CAGCATCACCACCACCACCACCACCAGCAGGCGCAACCTCAGCAAACGGTACCTCAGCAAGCAC
AGACCCAGCAGGTTCTTATTCCTGCGTCACAGCAAGCTACAGCACCACAAGTTATTGTTCCTGA
TTCTAAGTTGATACAACATATGAATGCATCAAGTATTACGAGTGCTGCTGCTACAGCTGCTACC
TTGGCGCTCCCTGCAGGCGTGACTCCTGTTCAGCAGATACTAACAAATTCAGGCCAGCTGCTTC
AGGTAGTCAGAGCAGCCAATGGTGCCCAATATATCTTTCAGCCTCAGCAGTCAGTTGTTCTACA
ACAACAAGTTATACCACAAATGCAGCCTGGTGGAGTACAAGCGCCTGTTATCCAGCAGGTCCTA
GCCCCACTTCCTGGAGGGATTTCACCACAGACCGGTGTCATCATCCAGCCACAGCAAATCTTAT
TTACAGGGAATAAGACTCAGGTCATTCCTACGACAGTGGCAGCGCCCACACCAGCACAAGCACA
GATCCCTGCAGCTGGACAGCAGCAGCCACAGGCCCAGCCTGCTCAGCAGCAGGCTCCATTGGTG
CTGCAAGTTGACGGAACAGGGGACACATCTTCTGAGGAAGATGAAGACGAAGAAGAAGACTATG
ATGATGATGAAGAGGAAGATAAAGAGAAAGATGGAGCCGAAGATGGGCAGGTGGAAGAAGAGCC
CCTCAACAGCGAAGATGATGTAAGTGATGAGGAAGGGCAGGAACTCTTTGACACAGAAAATGTT
GTTGTATGCCAGTATGATAAGATACACAGAAGTAAAAATAAATGGAAATTTCATCTCAAGGATG
GCATTATGAATCTTAATGGAAGAGATTATATATTTTCCAAAGCCATTGGAGATGCAGAGTGGTG
AAGAGTCGCTTCTTTCCTTTTATAAATAAGACAAAAGAAACTTAAAACGTTAACATGGACGGTT
TGAAACTTGGGACATATTTCAGCCAAACCTTCACTTCTGCATGTCAGAACAGCGCAGTAGAAGC
AAAGCTACGGGAACAAAGCTAGGCCTTGACCACATAGACACTACTTCAGACTGGCGAGCCATGG
AACTGTAGCACCTGGGGCTGCTGGGCGGGGGGAGGGGTTTGTGTAGGACAACTGTAACTGTCAA
TTTTAAATACAGGAACCTGCCATTGGTAATTAGCATGTAAAGCTTTGTCTATATTCGTTTCCAA
GTTGAGCTCAATCAGAAGATACGTGTTGGAATGACCTGAAGAAATTACCCTTTTGATAGATTGA
ACTGAAACTGCTTATTGTATGTGGTTATATTTGGTAAAAATTGCGTGTGAGCTTTTTACAGAAG
GGCAAGAATTATGGTGTTGAATTTTAATTCATTTGTATAAGAAAATTTAAAACTCATAATAGGT
CTTAAACATTTTTACTTGTTACTCTCCCTCAGTAAAATATACCTCTTGCTTCTCTGCTGTATGA
ACATCTACTTAAGATTTACAGAAAAAGATCAATGGCCACAGTTTGAGACAAAGTTGACCCAGGA
GTAGATGCTTGGTTTAATTAGGTTTTTATACTTGTTAAATGTGATTGAAAGACTTGGGTCTTAC
CTGTGTTATCTAGAATTAGAGGGACAGTTTAATTTCCTTACAGAAAAACTGCTCAGTCCCAGGC
TATGAGGAAACCCCAGATTGGCTCCTCAGGAATGTGTCTTTATTTCACAGAGGCACCACTGAGC
TGAAACTGTATAGTACACGTGCTACGCGAAGGTCTTTCTTGCCGGACTACAGTGTGTGCTTACC
TGTGCATTAGTCTCTGTAAACCCTGGGATGGCACTCTGTACATTGATCTAAGAAGCTTAAGGGC
AAGGCATGAGGACTGGGTTTTTATTAAACAATTTAGTAATTATAAAAGTTTCTTGTGTTTACTA
GTAAAGAATTTTAGAAATTATTTTAATTGAACAAAATTTTTAAAAAAACTTTGTAATTGGAGGG
AAAAGTTTGAGGGTGGAGGGGGTAGAGGAAAGTGGGCCACAAAATACAAATTTACCTCTTTCAT
TGGGTGGCTCTTCAGGCCATTGATGAGATACATAGACTTGCACATTGGAGAGAAAATACAGAGA
TTAGACTTGTATATTAAACCTGCAGACACGGCCATGTGCTGAGATGTGTAGCTCTGCTCCCGTA
TGGGGCTCTGCAGAACAAAGAGGTGCTGCAGTGAGCAGCTTCCTGGGACCTGCAGGGACACTCA
CTCTCCGTCACCTCTGTTCTAGTGACTAACAAAATTTGTGTTCAAGGTAACTTGCCTGTTGACT
TTTTTTTTTTTTTTTTGGTCTTCCATTTTTGTCTTCCTTTAATTTGACTTTATGTAGTTCTGGA
AGTAACAGATAAACTATAGTACAAAAGAAAAACTGTGAGCTATATAGTGCTTTTTTAAGTACAT
ATTTTAAAGTTTCTTAAAGCAGTTGATTTCTCCTCTCCACTTCCCCCTACTGAACCAATTTCTG
TTATGAAATTTGCTATCAGTGGTGGGGTCTTAACGTGATAGCAGTTAGATTTTGTATTCCATAA
CTGGTAATACAGGTTTTTTGTTTGTTCTTTTTTATTAATGTAGCTTCTTGAGGGGAAGTCTGTT
TAATCTCCTATTCTCAAAGCACACCGCAGTTCTGGTTGAACTAAACCTTGGTGAACAGAGGGCA
CAGGATCCCGAGAGTTGTTGAGTGGTCCCTTGCTATAGTTTCTAGGTGTGTGTTTACTCAGTGA
ATCAGTAACCTGAACTACCTACAGCAGCACAGCAGTGTGGCCGCAGTGGGACTAGTGGGCTATG
TTAGTGCCGCACATGCCCTGGCTTCTCTGTGTAGTCAGACATACTGAAGGTTAGCATTGAACAC
TGGCCTGTTTTCTAGCCAAAATGTTCAGACGTGAGCAACCACTTCTTTGAGAGTGAAGCAGGAA
CTGACCATTGATATTTGTATCTATGTGTACTGACTAATAATGCTGGCATCCTGGACAATACTGT
GATCTGGGAAAGCTCTGAAAACTGGTTCCAGCCGCCCTGCACACCAGACTGTGCTTTTCCATGC
TGTTATATTGTGCTCCTTTTAAATCAAGTAGCATGCTGCATTCCTCAGGATAGTAGCTTTTGCT
GTGTAATGTCACTTGCTTTGAATTTTCAATCATGCTTTCGCCATTACATTTAACCAATGATGTC
ATTAAGTTCTATTAAAGTGTCATTCCTTTGGGAAGCAAGGGATTCCCACTTGCAGAATTTTAAG
ATGAAGGTAGCATGTTTTGTTCAGAAGGTGGAAATAGGGACTCGAACAGTGTCTTCAGAAGCTG
ATCTGTTGAGATTTGTGTGCACAGTGAAGGCACCTCTTACATGATGTGAGGCCAGTAGCGCTAA
GGTAAATTTACACAGATGACTAAGGTGGGATGTGTGCCTTCCAGTCCATGAACTCTTGCCTGGT
GGTCGTTTGTATTCTCACACCACCAAAATGCCCGTGAGCACATGGGATTTCCTAGAGTAATACA
ACTTTGTCACGTGCAGTTTCTAGAGTCAAACAGGATAGGAGGGGGTCTTTATATTAGGCTTTTA
TATCTGAAATGTTCACATGTCTATTAAATGTGTCACACTTACACTGTTGCCTTTTGAAAAGTCA
GGCTGGCATCAAGATTCATGCAGTACATATAGTTATCAAAGTGTGTTATTGACAAGCATTCTGG
CTTTAGAAGGCAATGTAAAAAAATACTAATTTTTATATAAAGGCTTTCTTTTGCTGTATTGAAA
ATCAGGTTTTTCTTTTGGTGACTTGTATGGATGAATGCAGAGTTGTCTCCCTCTGAGAATATTT
TTTTTATTATCTTATAGCAATAATGTCACCATATTAGAGGGTAAGTATTCCTTGAATAAGAAAA
CACACATATCTCCTCTTAGCAGTTTTCCCTTTATAACAGCATTTTCTTCCACTTGAGAAGGCTC
TTATATTTTCATATTACTTCATCTTGAACTTTTGAGCTTTTGTGCAATGTGCTATTTTATTGGA
TCTTTGTACGTTTTCATTTCATGTTTCCTCCCTACCTGTCTGAAGCTGCTATAGCTGATGTTGG
GGTTTCGGTTAATGGTTATGTGTTTTCTCATCTTTATTAAAGTTAGGTTTATCTTTTAATTTGT
TACCCTTATGGAAATTATTCTGGTTTATACTCTTCCCCCTGGAAGCCTGCCTTTGTCCATCTGT
TATCTTACTTTCGTGCATGATTTAAGGAAGATTGCATCAAATTTAATATTTTTATTTTGAAGAA
GAAAAGCTTCCTACCATTTGAGGGGAGAACAAAACAACATTGAATAAAGAATTGGTCGTTCAGT
CAAACTTCCTTAAGTCAGTTCAGAATGCCTCGGTTACACCGATGGGGGCTCGTCCCTAGCTGGT
CAGAGTTACTGTTGTCGACTGCTGTTGTACATACTGTTATGTGTAAGGGCGTAAATATATTTAT
TATGTTTGTAAAATTCATTCTGTACACTTGCAGATCAAGGTTGCTCTTCTGTGATATATCGGGT
GTTACGTTTTAAAGACCATCTTGGAATACAACTAAAGAGCTTAGTATTTTGATGTACTAAGACT
ATTTTAAGTTTAATATTTTACCTTGCAAAAACTTTAATTAAAGATGTTATTTAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039112999 ⟹ XP_038968927

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	116,219,614 - 116,251,704 (-)	NCBI
mRatBN7.2	6	110,488,891 - 110,520,984 (-)	NCBI

RefSeq Acc Id:

XM_039113000 ⟹ XP_038968928

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	116,219,614 - 116,250,509 (-)	NCBI
mRatBN7.2	6	110,488,891 - 110,519,794 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_071544	(Get FASTA)	NCBI Sequence Viewer
	XP_006240472	(Get FASTA)	NCBI Sequence Viewer
	XP_038968927	(Get FASTA)	NCBI Sequence Viewer
	XP_038968928	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB58716	(Get FASTA)	NCBI Sequence Viewer
	EDL81672	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005873.1
	ENSRNOP00000086237
	ENSRNOP00000091168
GenBank Protein	O08949	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_071544 ⟸ NM_022208

- UniProtKB:

O08949 (UniProtKB/Swiss-Prot), A6JEC8 (UniProtKB/TrEMBL), A0A8I6A0U6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQ
QLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQH
MNASSITSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQ
MQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQIPAAGQ
QQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDD
VSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW

hide sequence

RefSeq Acc Id:	XP_006240472 ⟸ XM_006240410
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6APY1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQ QVLIPASQQATAPQVIVPDSKLIQHMNASSITSAAATAATLALPAGVTPVQQILTNSGQLLQVV RAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTG NKTQVIPTTVAAPTPAQAQIPAAGQQQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDD EEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIM NLNGRDYIFSKAIGDAEW hide sequence

Ensembl Acc Id:

ENSRNOP00000005873 ⟸ ENSRNOT00000005873

RefSeq Acc Id:	XP_038968927 ⟸ XM_039112999
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6APY1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968928 ⟸ XM_039113000
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6APY1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000086237 ⟸ ENSRNOT00000104002

Ensembl Acc Id:

ENSRNOP00000091168 ⟸ ENSRNOT00000119546

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O08949-F1-model_v2	AlphaFold	O08949	1-377	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694765

Promoter ID:

EPDNEW_R5289

Type:

single initiation site

Name:

Gtf2a1_1

Description:

general transcription factor 2A subunit 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	115,352,695 - 115,352,755	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69246	AgrOrtholog
BioCyc Gene	G2FUF-36653	BioCyc
Ensembl Genes	ENSRNOG00000004300	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000005873.4	UniProtKB/Swiss-Prot
	ENSRNOT00000104002	ENTREZGENE
	ENSRNOT00000119546	ENTREZGENE
Gene3D-CATH	1.10.287.100	UniProtKB/Swiss-Prot
	2.30.18.10	UniProtKB/Swiss-Prot
InterPro	TFIIA_asu/bsu	UniProtKB/Swiss-Prot
	TFIIA_b-brl	UniProtKB/Swiss-Prot
KEGG Report	rno:83830	UniProtKB/Swiss-Prot
NCBI Gene	83830	ENTREZGENE
PANTHER	PTHR12694	UniProtKB/Swiss-Prot
	TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1	UniProtKB/Swiss-Prot
Pfam	TFIIA	UniProtKB/Swiss-Prot
PhenoGen	Gtf2a1	PhenoGen
RatGTEx	ENSRNOG00000004300	RatGTEx
SMART	TFIIA	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50784	UniProtKB/Swiss-Prot
	Transcription factor IIA (TFIIA), alpha-helical domain	UniProtKB/Swiss-Prot
UniProt	A0A8I6A0U6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6APY1	ENTREZGENE, UniProtKB/TrEMBL
	A6JEC8	ENTREZGENE, UniProtKB/TrEMBL
	O08949	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-05-04	Gtf2a1	general transcription factor 2A subunit 1	Gtf2a1	general transcription factor IIA, 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-30	Gtf2a1	general transcription factor IIA, 1	Gtf2a1	general transcription factor II A, 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-06-27	Gtf2a1	general transcription factor II A, 1	Gtf2a1	general transcription factor 2a, 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2003-04-09	Gtf2a1	general transcription factor 2a, 1		general transcription factor 2a, 1	Symbol and Name updated	629477	APPROVED
2003-03-14	Gtf2a1	general transcription factor 2a, 1	Tf2a	TFIIA large subunit	Data merged from RGD:620303	628472	PROVISIONAL
2002-08-07	Tf2a	TFIIA large subunit			Symbol and Name status set to provisional	70820	PROVISIONAL
2002-06-10	Gtf2a1	general transcription factor 2a, 1			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

RGD Manual Annotations