Cxxc4 (CXXC finger protein 4) - Rat Genome Database

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Pathways
Gene: Cxxc4 (CXXC finger protein 4) Rattus norvegicus
Analyze
Symbol: Cxxc4
Name: CXXC finger protein 4
RGD ID: 69228
Description: Enables PDZ domain binding activity. Predicted to be involved in negative regulation of Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in cytoplasmic vesicle. Predicted to be active in nucleus. Orthologous to human CXXC4 (CXXC finger protein 4); PARTICIPATES IN Wnt signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CXXC finger 4; CXXC-type zinc finger protein 4; Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex); Idax; inhibition of the Dvl and axin complex protein; inhibitor of the Dvl and Axin complex
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Eau5
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82225,329,044 - 225,363,347 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.22222,664,148 - 222,689,365 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2222,664,771 - 222,689,365 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2230,361,717 - 230,386,485 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02228,261,412 - 228,286,180 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02223,126,229 - 223,150,995 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02239,414,882 - 239,439,640 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2239,415,046 - 239,439,568 (+)Ensemblrn6Rnor6.0
Rnor_5.02257,941,014 - 257,965,727 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42231,705,560 - 231,722,975 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2214,887,130 - 214,911,824 (+)NCBICelera
RGSC_v3.12231,692,299 - 231,709,701 (+)NCBI
Cytogenetic Map2q43NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
cytoplasmic vesicle  (ISO)
cytosol  (TAS)
nucleus  (IBA,ISO)

Molecular Function
DNA binding  (IEA)
metal ion binding  (IEA)
methyl-CpG binding  (IBA,ISO,ISS)
PDZ domain binding  (IPI,ISO)
protein binding  (IPI,ISO)
zinc ion binding  (IEA,ISO,ISS)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein. Hino S, etal., Mol Cell Biol 2001 Jan;21(1):330-42.
4. Interaction between the internal motif KTXXXI of Idax and mDvl PDZ domain. London TB, etal., Biochem Biophys Res Commun. 2004 Sep 10;322(1):326-32.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:23690950   PMID:29276034   PMID:32280999  


Genomics

Comparative Map Data
Cxxc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82225,329,044 - 225,363,347 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.22222,664,148 - 222,689,365 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2222,664,771 - 222,689,365 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2230,361,717 - 230,386,485 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02228,261,412 - 228,286,180 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02223,126,229 - 223,150,995 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02239,414,882 - 239,439,640 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2239,415,046 - 239,439,568 (+)Ensemblrn6Rnor6.0
Rnor_5.02257,941,014 - 257,965,727 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42231,705,560 - 231,722,975 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2214,887,130 - 214,911,824 (+)NCBICelera
RGSC_v3.12231,692,299 - 231,709,701 (+)NCBI
Cytogenetic Map2q43NCBI
CXXC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384104,468,308 - 104,494,894 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4104,468,308 - 104,494,901 (-)Ensemblhg38GRCh38
GRCh374105,389,465 - 105,416,051 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364105,612,779 - 105,631,916 (-)NCBIBuild 36Build 36hg18NCBI36
Build 344105,750,948 - 105,770,071NCBI
Celera4102,691,446 - 102,710,586 (-)NCBICelera
Cytogenetic Map4q24NCBI
HuRef4101,124,739 - 101,151,300 (-)NCBIHuRef
CHM1_14105,366,304 - 105,392,872 (-)NCBICHM1_1
T2T-CHM13v2.04107,779,515 - 107,806,100 (-)NCBIT2T-CHM13v2.0
Cxxc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393133,938,927 - 133,967,924 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3133,942,245 - 133,967,922 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm383134,236,144 - 134,262,163 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3134,236,484 - 134,262,161 (+)Ensemblmm10GRCm38
MGSCv373133,903,112 - 133,925,125 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363134,177,032 - 134,199,477 (+)NCBIMGSCv36mm8
Celera3140,656,700 - 140,678,444 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map362.12NCBI
Cxxc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554964,523,027 - 4,546,671 (+)Ensembl
ChiLan1.0NW_0049554964,523,027 - 4,546,671 (+)NCBIChiLan1.0ChiLan1.0
CXXC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23102,551,565 - 102,578,300 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14102,843,934 - 102,870,658 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0496,931,261 - 96,957,973 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14107,568,738 - 107,627,055 (-)NCBIPanPan1.1PanPan1.1panPan2
CXXC4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13225,469,736 - 25,492,226 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3225,473,758 - 25,492,262 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3216,532,739 - 16,555,823 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03225,679,514 - 25,701,609 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3225,681,895 - 25,712,769 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13225,700,838 - 25,723,930 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03225,442,770 - 25,465,858 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03214,394,495 - 14,417,610 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101958361
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530115,754,153 - 15,757,349 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367521,167,273 - 1,189,879 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367521,163,832 - 1,186,227 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXXC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8117,100,633 - 117,121,034 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.18117,094,442 - 117,124,943 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28125,972,942 - 125,994,265 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CXXC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1752,531,641 - 52,551,289 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603731,119,047 - 31,145,548 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cxxc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248304,092,850 - 4,115,959 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248304,090,207 - 4,116,080 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cxxc4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1324,377,706 - 24,399,240 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cxxc4
258 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:608
Count of miRNA genes:279
Interacting mature miRNAs:353
Transcripts:ENSRNOT00000072196
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631563Hcuc3Hepatic copper content QTL 33.87liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2212145502231732847Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2184482291229482291Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2202029709236904960Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2210956252251712708Rat
8693697Alc36Alcohol consumption QTL 3620.592drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2219814164239320906Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2214404877251712708Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2205135267225627153Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2204795005249795005Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2214404877251712708Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2218051934251712708Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2186850607231850607Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2192287802237287802Rat
1302789Stl26Serum triglyceride level QTL 263.10.0035blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)2206613059226891081Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2214404877251712708Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2196140964251540988Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2214404877251712708Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2205135267250135267Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2188565047233565047Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2192287802229609668Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2221088977243501206Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2184856304229856304Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2184856304229856304Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2182635347227635347Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2184856304229856304Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2203664411248664411Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2214404877251712708Rat
8693622Alc26Alcohol consumption QTL 262.40.667drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2223810546243965570Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2184856304229856304Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2192287802237287802Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2182024327227024327Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
1359019Hrtrt19Heart rate QTL 192.9heart pumping trait (VT:2000009)heart rate (CMO:0000002)2221270493228950743Rat

Markers in Region
RH134190  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22222,689,023 - 222,689,238 (+)MAPPERmRatBN7.2
Rnor_6.02239,439,299 - 239,439,513NCBIRnor6.0
Rnor_5.02257,965,458 - 257,965,672UniSTSRnor5.0
RGSC_v3.42231,726,499 - 231,726,713UniSTSRGSC3.4
Celera2214,911,483 - 214,911,697UniSTS
Cytogenetic Map2q43UniSTS
RH140132  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22222,669,355 - 222,669,553 (+)MAPPERmRatBN7.2
Rnor_6.02239,419,631 - 239,419,828NCBIRnor6.0
Rnor_5.02257,945,790 - 257,945,987UniSTSRnor5.0
RGSC_v3.42231,706,831 - 231,707,028UniSTSRGSC3.4
Celera2214,891,837 - 214,892,034UniSTS
RH 3.4 Map21559.5UniSTS
Cytogenetic Map2q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 67 159 91 90 59 85 59 6 340 185 11 137 73 90 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000072196   ⟹   ENSRNOP00000067828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2222,664,771 - 222,689,365 (+)Ensembl
Rnor_6.0 Ensembl2239,415,046 - 239,439,568 (+)Ensembl
RefSeq Acc Id: NM_053342   ⟹   NP_445794
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82225,338,589 - 225,363,347 (+)NCBI
mRatBN7.22222,664,607 - 222,689,365 (+)NCBI
Rnor_6.02239,414,882 - 239,439,640 (+)NCBI
Rnor_5.02257,941,014 - 257,965,727 (+)NCBI
RGSC_v3.42231,705,560 - 231,722,975 (+)RGD
Celera2214,887,130 - 214,911,824 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233339   ⟹   XP_006233401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82225,329,044 - 225,346,737 (+)NCBI
mRatBN7.22222,664,148 - 222,678,554 (+)NCBI
Rnor_6.02239,414,882 - 239,428,829 (+)NCBI
Rnor_5.02257,941,014 - 257,965,727 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233341   ⟹   XP_006233403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82225,329,044 - 225,346,737 (+)NCBI
mRatBN7.22222,664,148 - 222,678,554 (+)NCBI
Rnor_6.02239,414,889 - 239,428,829 (+)NCBI
Rnor_5.02257,941,014 - 257,965,727 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_445794 (Get FASTA)   NCBI Sequence Viewer  
  XP_006233401 (Get FASTA)   NCBI Sequence Viewer  
  XP_006233403 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG42071 (Get FASTA)   NCBI Sequence Viewer  
  EDL82242 (Get FASTA)   NCBI Sequence Viewer  
  Q9EQC9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445794   ⟸   NM_053342
- UniProtKB: M0RDW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233401   ⟸   XM_006233339
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006233403   ⟸   XM_006233341
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000067828   ⟸   ENSRNOT00000072196
Protein Domains
CXXC-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EQC9-F1-model_v2 AlphaFold Q9EQC9 1-198 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69228 AgrOrtholog
BioCyc Gene G2FUF-51149 BioCyc
Ensembl Genes ENSRNOG00000045764 Ensembl
InterPro CXXC4/CXXC5 UniProtKB/Swiss-Prot
  Znf_CXXC UniProtKB/Swiss-Prot
NCBI Gene 83824 ENTREZGENE
PANTHER CXXC FINGER PROTEIN 4 UniProtKB/Swiss-Prot
  PTHR13419 UniProtKB/Swiss-Prot
Pfam zf-CXXC UniProtKB/Swiss-Prot
PhenoGen Cxxc4 PhenoGen
PROSITE ZF_CXXC UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000045764 RatGTEx
TIGR TC210132
UniProt A6HVV6_RAT UniProtKB/TrEMBL
  CXXC4_RAT UniProtKB/Swiss-Prot
  M0RDW5 ENTREZGENE
  Q9EQC9 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Cxxc4  CXXC finger protein 4  Cxxc4  CXXC finger 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Cxxc4  CXXC finger 4  Idax  inhibitor of the Dvl and Axin complex  Symbol and Name updated 1299863 APPROVED
2002-06-10 Idax  inhibitor of the Dvl and Axin complex      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_process inhibits the Dvl and Axin complex 68802