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Gene: Rcan2 (regulator of calcineurin 2) Rattus norvegicus

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Symbol:

Rcan2

Name:

regulator of calcineurin 2

RGD ID:

69198

Description:

Predicted to enable calcium-dependent protein serine/threonine phosphatase regulator activity. Predicted to be involved in calcium-mediated signaling. Predicted to act upstream of or within several processes, including calcineurin-NFAT signaling cascade; locomotion involved in locomotory behavior; and short-term memory. Predicted to be active in cytoplasm and nucleus. Orthologous to human RCAN2 (regulator of calcineurin 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4,6-trinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

calcineurin inhibitory protein ZAKI-4; calcipressin-2; Dcip2; down syndrome candidate region 1-like protein 1; Down syndrome critical region gene 1-like 1; Down syndrome critical region gene1-like 1; Dscr1l1; MGC93057; Zaki-4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RCAN2 (regulator of calcineurin 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rcan2 (regulator of calcineurin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rcan2 (regulator of calcineurin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RCAN2 (regulator of calcineurin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RCAN2 (regulator of calcineurin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rcan2 (regulator of calcineurin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RCAN2 (regulator of calcineurin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RCAN2 (regulator of calcineurin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rcan2 (regulator of calcineurin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rcan2 (regulator of calcineurin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SYVN1 (synoviolin 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RCAN2 (regulator of calcineurin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rcan2 (regulator of calcineurin 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rcan2 (regulator of calcineurin 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RCN1	Alliance	DIOPT (OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	RCN1	Alliance	DIOPT (PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rcan-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	sra	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	sra	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rcan2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rcan2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	24,456,861 - 24,674,234 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	24,456,861 - 24,672,189 (-)	Ensembl				GRCr8
mRatBN7.2	9	16,959,478 - 17,174,823 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	16,959,480 - 17,174,856 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	25,543,367 - 25,758,360 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	30,617,888 - 30,832,887 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	28,907,100 - 29,122,117 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	19,518,568 - 19,749,145 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	19,518,558 - 19,749,145 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	18,397,065 - 18,626,606 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	12,623,121 - 12,853,302 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	14,685,543 - 14,899,643 (-)	NCBI		Celera
RGSC_v3.1	9	12,620,444 - 12,850,624 (-)	NCBI
Cytogenetic Map	9	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

metabolic dysfunction-associated steatotic liver disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

1,4-dioxane (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,6-trinitrotoluene (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

amphotericin B (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

beta-naphthoflavone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

cantharidin (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (EXP)

cobalt dichloride (EXP)

cyclosporin A (ISO)

DDT (EXP)

decabromodiphenyl ether (EXP)

dibutyl phthalate (ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

genistein (EXP)

gentamycin (EXP)

iron dichloride (ISO)

L-methionine (ISO)

lipopolysaccharide (ISO)

methapyrilene (ISO)

N-nitrosodiethylamine (EXP)

nefazodone (EXP)

nickel atom (ISO)

p-toluidine (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

permethrin (ISO)

phenobarbital (EXP,ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

raloxifene (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (EXP)

sulforaphane (ISO)

tamoxifen (ISO)

testosterone (ISO)

Theaflavin 3,3'-digallate (ISO)

thioacetamide (EXP)

trichloroethene (EXP,ISO)

trichostatin A (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (EXP,ISO)

valproic acid (ISO)

vinclozolin (EXP)

XL147 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcineurin-NFAT signaling cascade (ISO)

calcium-mediated signaling (IBA,IEA)

locomotion involved in locomotory behavior (ISO)

Notch signaling pathway (ISO)

response to oxidative stress (ISO)

response to stress (ISO)

short-term memory (ISO)

Cellular Component

cytoplasm (IBA)

nucleus (IBA)

Molecular Function

calcium-dependent protein serine/threonine phosphatase regulator activity (IBA)

nucleic acid binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Expression of ZAKI-4 messenger ribonucleic acid in the brain during rat development and the effect of hypothyroidism.	Siddiq A, etal., Endocrinology 2001 May;142(5):1752-9.
7.	Direct biomechanical induction of endogenous calcineurin inhibitor Down Syndrome Critical Region-1 in cardiac myocytes.	Wang Y, etal., Am J Physiol Heart Circ Physiol 2002 Aug;283(2):H533-9.

Additional References at PubMed

PMID:12477932	PMID:16648267	PMID:23117660

Genomics

Comparative Map Data

Rcan2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	24,456,861 - 24,674,234 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	24,456,861 - 24,672,189 (-)	Ensembl				GRCr8
mRatBN7.2	9	16,959,478 - 17,174,823 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	16,959,480 - 17,174,856 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	25,543,367 - 25,758,360 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	30,617,888 - 30,832,887 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	28,907,100 - 29,122,117 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	19,518,568 - 19,749,145 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	19,518,558 - 19,749,145 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	18,397,065 - 18,626,606 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	12,623,121 - 12,853,302 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	14,685,543 - 14,899,643 (-)	NCBI		Celera
RGSC_v3.1	9	12,620,444 - 12,850,624 (-)	NCBI
Cytogenetic Map	9	q13	NCBI

RCAN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	46,220,736 - 46,491,970 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	46,220,736 - 46,491,972 (-)	Ensembl			hg38	GRCh38
GRCh37	6	46,188,473 - 46,459,707 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	46,296,428 - 46,401,490 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	46,296,433 - 46,401,364	NCBI
Celera	6	47,741,020 - 47,846,061 (-)	NCBI		Celera
Cytogenetic Map	6	p12.3	NCBI
HuRef	6	45,911,564 - 46,182,793 (-)	NCBI		HuRef
CHM1_1	6	46,191,709 - 46,463,038 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	46,055,860 - 46,329,613 (-)	NCBI		T2T-CHM13v2.0

Rcan2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	44,112,243 - 44,350,407 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	44,112,242 - 44,350,407 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	43,801,352 - 44,039,516 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	43,801,351 - 44,039,516 (+)	Ensembl			mm10	GRCm38
MGSCv37	17	43,938,800 - 44,176,465 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	43,264,906 - 43,502,571 (+)	NCBI		MGSCv36	mm8
Celera	17	47,226,766 - 47,458,244 (+)	NCBI		Celera
Cytogenetic Map	17	B3	NCBI
cM Map	17	19.77	NCBI

Rcan2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	11,243,143 - 11,405,795 (-)	Ensembl
ChiLan1.0	NW_004955437	11,243,195 - 11,406,488 (-)	NCBI	ChiLan1.0	ChiLan1.0

RCAN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	60,713,940 - 60,987,123 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	56,580,011 - 56,853,215 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	45,801,389 - 46,074,620 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	47,074,850 - 47,347,556 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	47,074,850 - 47,312,149 (-)	Ensembl			panPan2	panpan1.1

RCAN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	14,427,095 - 14,647,327 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	14,428,406 - 14,687,241 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	14,458,631 - 14,718,983 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	14,927,188 - 15,187,200 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	14,927,180 - 15,187,355 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	14,442,961 - 14,703,496 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	14,531,756 - 14,791,823 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	14,628,322 - 14,888,571 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rcan2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	49,849,314 - 50,090,256 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	13,915,701 - 14,110,891 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	13,869,797 - 14,110,892 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RCAN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	40,980,527 - 41,282,835 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	40,979,814 - 41,282,869 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	47,364,244 - 47,451,587 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RCAN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	25,775,137 - 26,034,443 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	25,939,629 - 26,034,448 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666044	46,223,466 - 46,511,471 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rcan2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	14,086,096 - 14,250,567 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624754	14,086,947 - 14,250,473 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rcan2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	85,827,742 - 86,044,813 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rcan2
1423 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	1408
Count of miRNA genes:	323
Interacting mature miRNAs:	433
Transcripts:	ENSRNOT00000013956, ENSRNOT00000029593
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	6714888	84474983	Rat
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5346479	50346479	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	8750492	53750492	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	1	31250552	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	496645	45496645	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	6214995	51214995	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	8750492	53750492	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	41763315	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	5346479	50416711	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	6714888	29567695	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	496645	45496645	Rat
1600365	Mcs20	Mammary carcinoma susceptibility QTL 20	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	9	21031430	49025574	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	496645	45496645	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	6214995	51214995	Rat

Markers in Region

D9Rat36

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	16,961,398 - 16,961,545 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	19,520,489 - 19,520,635	NCBI	Rnor6.0
Rnor_5.0	9	18,398,986 - 18,399,132	UniSTS	Rnor5.0
RGSC_v3.4	9	12,625,042 - 12,625,188	UniSTS	RGSC3.4
RGSC_v3.4	9	12,625,041 - 12,625,186	RGD	RGSC3.4
Celera	9	14,687,464 - 14,687,610	UniSTS
RGSC_v3.1	9	12,622,363 - 12,622,508	RGD
RH 2.0 Map	9	91.1	RGD
SHRSP x BN Map	9	14.0098	RGD
FHH x ACI Map	9	11.26	RGD
Cytogenetic Map	9	q12	UniSTS

D9Rat66

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	9	24,541,450 - 24,541,656 (+)	Marker Load Pipeline
mRatBN7.2	9	17,044,075 - 17,044,281 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	19,613,434 - 19,613,639	NCBI	Rnor6.0
Rnor_5.0	9	18,492,020 - 18,492,225	UniSTS	Rnor5.0
RGSC_v3.4	9	12,718,424 - 12,718,629	RGD	RGSC3.4
RGSC_v3.4	9	12,718,425 - 12,718,630	UniSTS	RGSC3.4
Celera	9	14,770,349 - 14,770,554	UniSTS
RGSC_v3.1	9	12,715,743 - 12,716,211	RGD
RH 2.0 Map	9	111.5	RGD
SHRSP x BN Map	9	14.0098	RGD
FHH x ACI Map	9	11.19	RGD
Cytogenetic Map	9	q12	UniSTS

D9Rat78

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	9	24,504,535 - 24,504,778 (+)	Marker Load Pipeline
mRatBN7.2	9	17,007,152 - 17,007,395 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	19,566,867 - 19,567,109	NCBI	Rnor6.0
Rnor_5.0	9	18,445,364 - 18,445,606	UniSTS	Rnor5.0
RGSC_v3.4	9	12,671,423 - 12,671,665	UniSTS	RGSC3.4
RGSC_v3.4	9	12,671,417 - 12,671,665	RGD	RGSC3.4
Celera	9	14,733,567 - 14,733,815	UniSTS
RGSC_v3.1	9	12,668,745 - 12,668,987	RGD
RH 3.4 Map	9	102.1	RGD
RH 3.4 Map	9	102.1	UniSTS
RH 2.0 Map	9	89.9	RGD
SHRSP x BN Map	9	15.0998	RGD
FHH x ACI Map	9	11.19	RGD
Cytogenetic Map	9	q12	UniSTS

D9Rat193

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	17,111,709 - 17,111,930 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	19,686,780 - 19,687,000	NCBI	Rnor6.0
Rnor_5.0	9	18,564,617 - 18,564,837	UniSTS	Rnor5.0
RGSC_v3.4	9	12,789,442 - 12,789,663	RGD	RGSC3.4
RGSC_v3.4	9	12,789,443 - 12,789,663	UniSTS	RGSC3.4
Celera	9	14,838,072 - 14,838,292	UniSTS
RGSC_v3.1	9	12,786,764 - 12,786,985	RGD
FHH x ACI Map	9	11.19	UniSTS
FHH x ACI Map	9	11.19	RGD
Cytogenetic Map	9	q12	UniSTS

D9Got19

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	17,092,452 - 17,092,701 (+)	MAPPER	mRatBN7.2
mRatBN7.2	2	192,261,793 - 192,263,017 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	207,246,641 - 207,247,864	NCBI	Rnor6.0
Rnor_6.0	9	19,667,346 - 19,667,592	NCBI	Rnor6.0
Rnor_5.0	9	18,545,183 - 18,545,429	UniSTS	Rnor5.0
Rnor_5.0	2	226,666,272 - 226,667,495	UniSTS	Rnor5.0
RGSC_v3.4	9	12,770,190 - 12,770,436	UniSTS	RGSC3.4
RGSC_v3.4	2	200,022,638 - 200,023,861	UniSTS	RGSC3.4
RGSC_v3.4	9	12,770,189 - 12,770,436	RGD	RGSC3.4
Celera	9	14,818,832 - 14,819,078	UniSTS
Celera	2	184,728,678 - 184,729,901	UniSTS
RGSC_v3.1	9	12,767,512 - 12,767,758	RGD
RH 3.4 Map	9	118.29	RGD
RH 3.4 Map	9	118.29	UniSTS
Cytogenetic Map	2	q34	UniSTS
Cytogenetic Map	9	q12	UniSTS

D9Got24

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	17,119,986 - 17,120,201 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	19,695,057 - 19,695,271	NCBI	Rnor6.0
Rnor_5.0	9	18,572,894 - 18,573,108	UniSTS	Rnor5.0
RGSC_v3.4	9	12,797,719 - 12,797,934	RGD	RGSC3.4
RGSC_v3.4	9	12,797,720 - 12,797,934	UniSTS	RGSC3.4
Celera	9	14,846,353 - 14,846,567	UniSTS
RGSC_v3.1	9	12,795,041 - 12,795,256	RGD
Cytogenetic Map	9	q12	UniSTS

Dscr1l1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	16,961,773 - 16,962,003 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	19,520,864 - 19,521,093	NCBI	Rnor6.0
Rnor_5.0	9	18,399,361 - 18,399,590	UniSTS	Rnor5.0
RGSC_v3.4	9	12,625,417 - 12,625,646	UniSTS	RGSC3.4
Celera	9	14,687,839 - 14,688,068	UniSTS
Cytogenetic Map	9	q12	UniSTS

BF401166

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	17,029,190 - 17,029,284 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	19,598,539 - 19,598,632	NCBI	Rnor6.0
Rnor_6.0	9	19,587,946 - 19,588,039	NCBI	Rnor6.0
Rnor_5.0	9	18,477,036 - 18,477,129	UniSTS	Rnor5.0
Rnor_5.0	9	18,466,443 - 18,466,536	UniSTS	Rnor5.0
RGSC_v3.4	9	12,692,945 - 12,693,038	UniSTS	RGSC3.4
Celera	9	14,755,610 - 14,755,703	UniSTS
RH 3.4 Map	9	102.0	UniSTS
Cytogenetic Map	9	q12	UniSTS

RH133146

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	16,959,533 - 16,959,743 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	19,518,624 - 19,518,833	NCBI	Rnor6.0
Rnor_5.0	9	18,397,121 - 18,397,330	UniSTS	Rnor5.0
RGSC_v3.4	9	12,623,177 - 12,623,386	UniSTS	RGSC3.4
Celera	9	14,685,599 - 14,685,808	UniSTS
Cytogenetic Map	9	q12	UniSTS

BF398967

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	17,164,041 - 17,164,156 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	19,738,844 - 19,738,958	NCBI	Rnor6.0
Rnor_5.0	9	18,616,305 - 18,616,419	UniSTS	Rnor5.0
RGSC_v3.4	9	12,842,533 - 12,842,647	UniSTS	RGSC3.4
Celera	9	14,890,469 - 14,890,583	UniSTS
RH 3.4 Map	9	107.0	UniSTS
Cytogenetic Map	9	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	12	67	165	91	90	59	65	59	6	328	165	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_175578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006244593	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266599	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266600	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF459022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF459023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000013956 ⟹ ENSRNOP00000013954

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	24,456,861 - 24,672,189 (-)	Ensembl
mRatBN7.2 Ensembl	9	16,959,480 - 17,174,856 (-)	Ensembl
Rnor_6.0 Ensembl	9	19,518,570 - 19,749,145 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000029593 ⟹ ENSRNOP00000029489

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	24,459,098 - 24,541,282 (-)	Ensembl
mRatBN7.2 Ensembl	9	16,961,715 - 17,043,907 (-)	Ensembl
Rnor_6.0 Ensembl	9	19,518,558 - 19,613,360 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000121169 ⟹ ENSRNOP00000101837

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	24,456,861 - 24,639,713 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000127914 ⟹ ENSRNOP00000106545

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	24,456,861 - 24,502,177 (-)	Ensembl

RefSeq Acc Id:

NM_175578 ⟹ NP_783168

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	24,456,861 - 24,672,189 (-)	NCBI
mRatBN7.2	9	16,959,478 - 17,174,823 (-)	NCBI
Rnor_6.0	9	19,518,568 - 19,749,145 (-)	NCBI
Rnor_5.0	9	18,397,065 - 18,626,606 (-)	NCBI
RGSC_v3.4	9	12,623,121 - 12,853,302 (-)	RGD
Celera	9	14,685,543 - 14,899,643 (-)	RGD

Sequence:

show sequence

GTTGCGGGAGCACCAGCAGGAGGCACAGCCCGGGTGACCCTGCGACCCGGAGAGCGGGAGGCGG
CGCTCAGTGCGCACGGTTCCACGCCCAGGCCCGCGGGCACCGCGCTCACCCCGGCCGTCAGGTG
AGCAGGCAGAGCCGCGCCCGCAGCCTGCTGCCCCGAGGACCCTCGAGCCGCCACCACTGTCACC
GCCGCCACAGCGGCGCATCGCAGACGTCCTGCAGGGATGAGGGGAGACGCCTACTTCATTGGAA
TGAGGAGCCTAGGGCAGCAGGCATCGGTCCCTGAAGATGGGGGACTTTTCTTCCTCTGCTGCAT
AGACAGAGACTGGGCTGTCACTCAGTGTTTTGCTGAAGAGGCCTTCCAAGCACTCACCGACTTC
AATGATCTCCCCAACTCATTGTTTGCCTGCAATGTTCACCAGTCCGTGTTTGAAGAAGAAGAGA
GCAAGGAAAAATTTGAGGGACTGTTCCGGACCTATGACGAATGTGTGACGTTTCAGCTGTTTAA
GAGTTTCCGACGGGTTCGAATAAATTTCAGCCACCCCAAAGCTGCAGCCCGTGCCCGGATAGAG
CTTCATGAGACCCAGTTCAGAGGGAAGAAGCTGAAACTCTACTTTGCACAGGTCCAGACCCCAG
AGACAGATGGAGACAAACTGCATTTGGCACCCCCACAGCCTGCCAAACAGTTCCTCATCTCACC
CCCTTCATCTCCTCCCGTTGGCTGGAAGCCTATCAGCGATGCCACACCAGTCCTCAACTACGAC
CTCCTTTATGCCGTGGCCAAACTAGGACCAGGAGAGAAATATGAGCTGCATGCGGGAACTGAGT
CTACACCGAGCGTTGTCGTGCACGTGTGTGACAGCGACTTGGAGGAGGAGGAGGATCCAAAGAC
TTCCCCAAAGCCAAAAATCATCCAGACCCGGCGTCCTGGCCTGCCACCCTCCGTGTCCAACTGA
GCACGTCCATGATAACATGCATCTCCTCTTATCATGCTTTTTCTCCCTTGTTCGTCCAAAAATT
AATTGCCTTGAAGTCCCTGGGTGTTTGGTTGTTTGAGAATCCTTCCTTGTAATTAAGCCTCTCG
GACAAAAGGGCTAGGAAAAGGTGATATGTCTCCCAGTCAACTCATACCCATTAACCAGAGTCCA
TTATTTAGAAAGTTCTAGACAAAGGGTAGTATTTTCTTATTAAACAATCAGTACAGCCTATATC
TCTGTTCTCTCATGTTGATCCAAGCCAGAGACATCAGTAACCAATAGCCTTCATGTTGTTTGTG
AGCTGCTCCAATTGAGTCCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT
ATGTGTGTGTGTGTGTTGTTTATTCCTGGCCACTTATATAGGACCATAAGTAAACTTGGCTTTG
ACTGCATGAGATCCCCCTATCTGGTCTCACCCAGTCCTCTGCATCCCGACATTCCCAGGACATG
CACAATCACCAGCATTTATTTTGATGATTTGAGGGTATGCCCCACCTTGTGGTATCCCAGCCCT
GTCCTGTATAGACAAGGGGCATCCACGGCACCATTTGGCTCAATAAGTCTGGGAATCATGATTA
GTTTGAGTCAATACATCATCGTATAGCTTTGTCCAAATTCCTGGAGGTAAAATTGAGCGTGGCC
CCAAAGAGATTCCTCAGTAGATTCTAAACATCACTATCACATAGGACTACCCAGTGCTACTGGG
GAGGCTTGCCCGAGTGACAGAGACCGATTTCAGACAAACCTATTTATTATAAAAGTCTCACAGT
GTCTGAATGATTGTCGTCCCCCCCCACCTCTTTGTATATTTGTACAGATGTTTGAGCTGTGCTT
TTAAAATCTGGATTTTTTTTTTTTTTGATTTAGTGATTGTTCAACCATTAGCTGCTTAATGACA
TCATACCTGTGTTGCTTCTGAATGCATCCTGATTCTAATGTAGATAATCCGATACTATCACACG
CTATTACGGTTCATGCTATGTTGTAAAAGGCTACAGCAATGTCTCATGCCAATAGATAAACGAC
TAGCTAATTTCTTTGCTGTCAAGATCACCTGTTTGCAAACAAAGATCCAAGTATCAGTTGTAAG
CAACTTGGGTGGCGCTTAATCCAAGATCGTATACAGCTGAGCATTTCCGAACACAAAGGATGAT
GGGTAAACGGACGGCCCCTCCCATTCATCCAGTGCCCGTGTGCTCAAAAGTTCCTTGTTTTCGT
TACCTGTGATTTTGTATTTCTCTAGCCCAAAGTGCATTACAGAAGATACACCTGCAGAACCATA
CTTTCTGCTCCATGTGTCAAGCCTCATCTATTCCTGTTCATTAACTAGTAACTTTGGATGCAAA
TACTATTTACCACACAACGGGCAAGGACTTCAATGACCTAAGCCTCAGAATACCACACAAGAAC
ACTAACACAGCCACCTGATGGGGGGATTATGTGGTTTTTTGACTAAGGTGTATGTTAGTTTCAG
CAGAAACTTCAAACCTAGACTGATCACTCAGAAAATTAAAGTCCGTTCTACTGTGAAATATAGC
AATATAGTGCCGGACACGGTACAGTACGGTTGAGACCGAGGCCAGCATTGCTTGTGGAATCCTG
AGTTTCCACGGGGATAACAAGTCTCCTTTTCAAACTCAGATCTGAGGAGTGTACAGCAAAGGCT
TTGACTTTCCTTTGTTGTGGAAGGATTTGGTTTTTTCATTGGCCACGGAACGACTACAAATAGT
GGCGAGATGCTGCCCTCTGGTGGCCGAAACGTTGAACTCGGTTGTATAGGTGGATTGATTACAA
CAGTCAACTCCCAGGGTCTGACTTTCTAATCCGCGTTAACTTTCAGGATGCAGGTTCTGAGAAA
GAGAGAAAAATGAACAGTCTAAATGAGATTAAAGCCTTGGAAATAATTTGTGCTTCCAAACAAT
GATAGCAGAGATTTCCAGTTTAGTAAAAGTTGATGTGACTACCTTGGGTAGGCATTAAGAACTC
AGTGTTACAGATGGCCCAGGTGATTAGTCTTAGTAAACTGTATTGCCATATGTCGATGTTAACC
TGCTGCAGAGCAAGGGATTCTCGCACTAGGTTGAGCACGGAGAGGGGAGAAGGGGAGCTTTCCC
CAGAAAGAATAGGGAAGCCATGGGACCTCCCAGCACCGAGAAAGTCGCCTCAACACTTCCTTCC
ATGATGCTCATTATGCAAACCTCTTTAGCGCTCTTTTTAAGTTTGAAACGTTTTAAATGGAGGG
GAAGGGGAAGGTTTCCACCAACTGAATCATTTGTGCACGTGTAAAGCTCAAAGAGCTTAGAGTT
CAAATATATCTGGTGAATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006244593 ⟹ XP_006244655

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	24,456,861 - 24,541,679 (-)	NCBI
mRatBN7.2	9	16,959,478 - 17,044,063 (-)	NCBI
Rnor_6.0	9	19,518,568 - 19,613,468 (-)	NCBI
Rnor_5.0	9	18,397,065 - 18,626,606 (-)	NCBI

Sequence:

show sequence

TGTGTGTTGGAGGGGGGAGCAGCTTCAGCTTGTGTCGGCCTCTGTGATGATGTCATTGGCATGA
GAGAGAGAGAGAGAGCCTGGTGCTTCTTTACTCTGCTGTGCTGCCTCAGAAGCTGCTTGCAGCG
GCAGCAGGCTCCAGGTGGCTGAGTCTCCAACCAGCACCGCACCGCACCCCACCTCCCCCCCAGA
AGCAGGGCAGTACCAGGACAGTATCCATCCAGAGGAGTCTCTTCACTCCCAACTCTGAGGCTGC
CTAACTCTTCGCTGAGAATTCCGAAGAGGGGAATGCCAGCCCCTAGCATGGACTGTGATGTTTC
CACTCTGGTCGCCTGTGTGGTGGATGTGGAGGTCTTTACCAATCAGGAGGTTAAGGAAAAATTT
GAGGGACTGTTCCGGACCTATGACGAATGTGTGACGTTTCAGCTGTTTAAGAGTTTCCGACGGG
TTCGAATAAATTTCAGCCACCCCAAAGCTGCAGCCCGTGCCCGGATAGAGCTTCATGAGACCCA
GTTCAGAGGGAAGAAGCTGAAACTCTACTTTGCACAGGTCCAGACCCCAGAGACAGATGGAGAC
AAACTGCATTTGGCACCCCCACAGCCTGCCAAACAGTTCCTCATCTCACCCCCTTCATCTCCTC
CCGTTGGCTGGAAGCCTATCAGCGATGCCACACCAGTCCTCAACTACGACCTCCTTTATGCCGT
GGCCAAACTAGGACCAGGAGAGAAATATGAGCTGCATGCGGGAACTGAGTCTACACCGAGCGTT
GTCGTGCACGTGTGTGACAGCGACTTGGAGGAGGAGGAGGATCCAAAGACTTCCCCAAAGCCAA
AAATCATCCAGACCCGGCGTCCTGGCCTGCCACCCTCCGTGTCCAACTGAGCACGTCCATGATA
ACATGCATCTCCTCTTATCATGCTTTTTCTCCCTTGTTCGTCCAAAAATTAATTGCCTTGAAGT
CCCTGGGTGTTTGGTTGTTTGAGAATCCTTCCTTGTAATTAAGCCTCTCGGACAAAAGGGCTAG
GAAAAGGTGATATGTCTCCCAGTCAACTCATACCCATTAACCAGAGTCCATTATTTAGAAAGTT
CTAGACAAAGGGTAGTATTTTCTTATTAAACAATCAGTACAGCCTATATCTCTGTTCTCTCATG
TTGATCCAAGCCAGAGACATCAGTAACCAATAGCCTTCATGTTGTTTGTGAGCTGCTCCAATTG
AGTCCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTGTGTGTGT
GTTGTTTATTCCTGGCCACTTATATAGGACCATAAGTAAACTTGGCTTTGACTGCATGAGATCC
CCCTATCTGGTCTCACCCAGTCCTCTGCATCCCGACATTCCCAGGACATGCACAATCACCAGCA
TTTATTTTGATGATTTGAGGGTATGCCCCACCTTGTGGTATCCCAGCCCTGTCCTGTATAGACA
AGGGGCATCCACGGCACCATTTGGCTCAATAAGTCTGGGAATCATGATTAGTTTGAGTCAATAC
ATCATCGTATAGCTTTGTCCAAATTCCTGGAGGTAAAATTGAGCGTGGCCCCAAAGAGATTCCT
CAGTAGATTCTAAACATCACTATCACATAGGACTACCCAGTGCTACTGGGGAGGCTTGCCCGAG
TGACAGAGACCGATTTCAGACAAACCTATTTATTATAAAAGTCTCACAGTGTCTGAATGATTGT
CGTCCCCCCCCACCTCTTTGTATATTTGTACAGATGTTTGAGCTGTGCTTTTAAAATCTGGATT
TTTTTTTTTTTGATTTAGTGATTGTTCAACCATTAGCTGCTTAATGACATCATACCTGTGTTGC
TTCTGAATGCATCCTGATTCTAATGTAGATAATCCGATACTATCACACGCTATTACGGTTCATG
CTATGTTGTAAAAGGCTACAGCAATGTCTCATGCCAATAGATAAACGACTAGCTAATTTCTTTG
CTGTCAAGATCACCTGTTTGCAAACAAAGATCCAAGTATCAGTTGTAAGCAACTTGGGTGGCGC
TTAATCCAAGATCGTATACAGCTGAGCATTTCCGAACACAAAGGATGATGGGTAAACGGACGGC
CCCTCCCATTCATCCAGTGCCCGTGTGCTCAAAAGTTCCTTGTTTTCGTTACCTGTGATTTTGT
ATTTCTCTAGCCCAAAGTGCATTACAGAAGATACACCTGCAGAACCATACTTTCTGCTCCATGT
GTCAAGCCTCATCTATTCCTGTTCATTAACTAGTAACTTTGGATGCAAATACTATTTACCACAC
AACGGGCAAGGACTTCAATGACCTAAGCCTCAGAATACCACACAAGAACACTAACACAGCCACC
TGATGGGGGGATTATGTGGTTTTTTGACTAAGGTGTATGTTAGTTTCAGCAGAAACTTCAAACC
TAGACTGATCACTCAGAAAATTAAAGTCCGTTCTACTGTGAAATATAGCAATATAGTGCCGGAC
ACGGTACAGTACGGTTGAGACCGAGGCCAGCATTGCTTGTGGAATCCTGAGTTTCCACGGGGAT
AACAAGTCTCCTTTTCAAACTCAGATCTGAGGAGTGTACAGCAAAGGCTTTGACTTTCCTTTGT
TGTGGAAGGATTTGGTTTTTTCATTGGCCACGGAACGACTACAAATAGTGGCGAGATGCTGCCC
TCTGGTGGCCGAAACGTTGAACTCGGTTGTATAGGTGGATTGATTACAACAGTCAACTCCCAGG
GTCTGACTTTCTAATCCGCGTTAACTTTCAGGATGCAGGTTCTGAGAAAGAGAGAAAAATGAAC
AGTCTAAATGAGATTAAAGCCTTGGAAATAATTTGTGCTTCCAAACAATGATAGCAGAGATTTC
CAGTTTAGTAAAAGTTGATGTGACTACCTTGGGTAGGCATTAAGAACTCAGTGTTACAGATGGC
CCAGGTGATTAGTCTTAGTAAACTGTATTGCCATATGTCGATGTTAACCTGCTGCAGAGCAAGG
GATTCTCGCACTAGGTTGAGCACGGAGAGGGGAGAAGGGGAGCTTTCCCCAGAAAGAATAGGGA
AGCCATGGGACCTCCCAGCACCGAGAAAGTCGCCTCAACACTTCCTTCCATGATGCTCATTATG
CAAACCTCTTTAGCGCTCTTTTTAAGTTTGAAACGTTTTAAATGGAGGGGAAGGGGAAGGTTTC
CACCAACTGAATCATTTGTGCACGTGTAAAGCTCAAAGAGCTTAGAGTTCAAATATATCTGGTG
AATGAA

hide sequence

RefSeq Acc Id:

XM_063266599 ⟹ XP_063122669

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	24,456,861 - 24,674,234 (-)	NCBI

RefSeq Acc Id:

XM_063266600 ⟹ XP_063122670

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	24,456,861 - 24,671,871 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_783168	(Get FASTA)	NCBI Sequence Viewer
	XP_006244655	(Get FASTA)	NCBI Sequence Viewer
	XP_063122669	(Get FASTA)	NCBI Sequence Viewer
	XP_063122670	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86974	(Get FASTA)	NCBI Sequence Viewer
	AAO15540	(Get FASTA)	NCBI Sequence Viewer
	AAO15541	(Get FASTA)	NCBI Sequence Viewer
	EDM18707	(Get FASTA)	NCBI Sequence Viewer
	EDM18708	(Get FASTA)	NCBI Sequence Viewer
	EDM18709	(Get FASTA)	NCBI Sequence Viewer
	EDM18710	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000013954
	ENSRNOP00000029489
	ENSRNOP00000029489.3
GenBank Protein	Q8CH27	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_783168 ⟸ NM_175578

- UniProtKB:

A0A0G2JSK3 (UniProtKB/TrEMBL), A6JJ23 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRGDAYFIGMRSLGQQASVPEDGGLFFLCCIDRDWAVTQCFAEEAFQALTDFNDLPNSLFACNV
HQSVFEEEESKEKFEGLFRTYDECVTFQLFKSFRRVRINFSHPKAAARARIELHETQFRGKKLK
LYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPPVGWKPISDATPVLNYDLLYAVAKLGPGE
KYELHAGTESTPSVVVHVCDSDLEEEEDPKTSPKPKIIQTRRPGLPPSVSN

hide sequence

RefSeq Acc Id:	XP_006244655 ⟸ XM_006244593
- Peptide Label:	isoform X2
- UniProtKB:	Q8CH26 (UniProtKB/Swiss-Prot), Q8CH27 (UniProtKB/Swiss-Prot), A6JJ25 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPAPSMDCDVSTLVACVVDVEVFTNQEVKEKFEGLFRTYDECVTFQLFKSFRRVRINFSHPKAA ARARIELHETQFRGKKLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPPVGWKPISDAT PVLNYDLLYAVAKLGPGEKYELHAGTESTPSVVVHVCDSDLEEEEDPKTSPKPKIIQTRRPGLP PSVSN hide sequence

Ensembl Acc Id:

ENSRNOP00000029489 ⟸ ENSRNOT00000029593

Ensembl Acc Id:

ENSRNOP00000013954 ⟸ ENSRNOT00000013956

RefSeq Acc Id:	XP_063122669 ⟸ XM_063266599
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JSK3 (UniProtKB/TrEMBL), A6JJ23 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063122670 ⟸ XM_063266600
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JSK3 (UniProtKB/TrEMBL), A6JJ23 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000106545 ⟸ ENSRNOT00000127914

Ensembl Acc Id:

ENSRNOP00000101837 ⟸ ENSRNOT00000121169

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8CH27-F1-model_v2	AlphaFold	Q8CH27	1-197	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696559

Promoter ID:

EPDNEW_R7076

Type:

multiple initiation site

Name:

Rcan2_2

Description:

regulator of calcineurin 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R7077

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	19,613,357 - 19,613,417	EPDNEW

RGD ID:

13696553

Promoter ID:

EPDNEW_R7077

Type:

multiple initiation site

Name:

Rcan2_1

Description:

regulator of calcineurin 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R7076

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	19,749,175 - 19,749,235	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69198	AgrOrtholog
BioCyc Gene	G2FUF-28122	BioCyc
Ensembl Genes	ENSRNOG00000010350	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000013956	ENTREZGENE
	ENSRNOT00000029593	ENTREZGENE
	ENSRNOT00000029593.5	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.70.330	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7193921	IMAGE-MGC_LOAD
InterPro	Calcipressin	UniProtKB/Swiss-Prot
	Nucleotide-bd_a/b_plait_sf	UniProtKB/Swiss-Prot
	RBD_domain_sf	UniProtKB/Swiss-Prot
	RCAN2_RRM	UniProtKB/Swiss-Prot
KEGG Report	rno:140666	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93057	IMAGE-MGC_LOAD
NCBI Gene	140666	ENTREZGENE
PANTHER	PTHR10300	UniProtKB/Swiss-Prot
	PTHR10300:SF5	UniProtKB/Swiss-Prot
Pfam	Calcipressin	UniProtKB/Swiss-Prot
PhenoGen	Rcan2	PhenoGen
RatGTEx	ENSRNOG00000010350	RatGTEx
Superfamily-SCOP	SSF54928	UniProtKB/Swiss-Prot
UniProt	A0A0G2JSK3	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L8F1_RAT	UniProtKB/TrEMBL
	A0ABK0L9R4_RAT	UniProtKB/TrEMBL
	A6JJ23	ENTREZGENE, UniProtKB/TrEMBL
	A6JJ25	ENTREZGENE, UniProtKB/TrEMBL
	Q8CH26	ENTREZGENE
	Q8CH27	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q8CH26	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-18	Rcan2	regulator of calcineurin 2	Dscr1l1	Down syndrome critical region gene 1-like 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Dscr1l1	Down syndrome critical region gene 1-like 1		Down syndrome critical region gene1-like 1	Name updated	1299863	APPROVED
2002-06-10	Dscr1l1	down syndrome critical region gene1-like 1			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_disease	deficiency may result in abnormal brain development by hypothyroidism	68685
gene_expression	detected in both cerebral cortex and cerebellum in early embryonic days, unchanged by age or thyroid status	68685
gene_expression	expressed in cardiac myocytes	625605
gene_function	functions as a calcineurin inhibitor	68685
gene_process	may have a role in brain development and function by modulating calcineurin function	68685
gene_process	calcineurin inhibitor	625605
gene_regulation	mechanical strain induces the mRNA	625605

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD