Fabp3 (fatty acid binding protein 3) - Rat Genome Database

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Gene: Fabp3 (fatty acid binding protein 3) Rattus norvegicus
Analyze
Symbol: Fabp3
Name: fatty acid binding protein 3
RGD ID: 69048
Description: Enables icosatetraenoic acid binding activity and long-chain fatty acid transmembrane transporter activity. Involved in several processes, including long-chain fatty acid transport; response to fatty acid; and response to insulin. Located in sarcoplasm. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human FABP3 (fatty acid binding protein 3); PARTICIPATES IN integrin mediated signaling pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; INTERACTS WITH (R)-adrenaline; (R)-carnitine; 1,3,4-thiadiazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fatty acid binding protein 3 heart; Fatty acid binding protein 3 muscle and heart; Fatty acid binding protein 3, heart; fatty acid binding protein 3, muscle and heart; fatty acid-binding protein 3; fatty acid-binding protein, heart; H-FABP; heart fatty acid binding protein; heart-type fatty acid-binding protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85147,936,027 - 147,942,870 (+)NCBIGRCr8
mRatBN7.25142,651,962 - 142,658,707 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5142,651,956 - 142,658,718 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5145,351,237 - 145,357,980 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05147,121,043 - 147,127,786 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05147,118,434 - 147,125,177 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05148,528,854 - 148,535,597 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5148,528,725 - 148,535,565 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05152,246,250 - 152,252,993 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45149,340,525 - 149,347,268 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15149,350,578 - 149,357,307 (+)NCBI
Celera5141,118,398 - 141,125,141 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
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Original Reference(s)
Fabp3RatAlzheimer's disease  ISOFABP3 (Homo sapiens)1578460protein:decreased expression:cerebral cortex (human)RGD 
Fabp3RatDown syndrome  ISOFABP3 (Homo sapiens)1578460protein:decreased expression:cerebral cortex (human)RGD 
Fabp3RatExperimental Diabetes Mellitus  IEP 2307330mRNA and protein:decreased expression:aortaRGD 
Fabp3Rathypertension susceptibilityISOFABP3 (Homo sapiens)2307331DNA:SNPsRGD 
Fabp3RatInsulin Resistance severityISOFabp3 (Mus musculus)1578459 RGD 
Fabp3Ratmyocardial infarction  ISOFABP3 (Homo sapiens)1582401 RGD 
Fabp3Ratobesity  ISOFABP3 (Homo sapiens)2307328associated with Diabetes Mellitus more ...RGD 
Fabp3Rattype 2 diabetes mellitus susceptibilityISOFABP3 (Homo sapiens)1578461DNA:deletion:3' utr:c.634+483delT (human)RGD 
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Original Reference(s)
Fabp3Ratmuscular disease  ISOFABP3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18308699
Fabp3RatNecrosis  ISOFABP3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18308699

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Original Reference(s)
Fabp3Rat(R)-adrenaline affects expressionEXP 6480464Epinephrine affects the expression of FABP3 proteinCTDPMID:19464573
Fabp3Rat(R)-adrenaline multiple interactionsEXP 6480464[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of FABP3 proteinCTDPMID:19464573
Fabp3Rat(R)-carnitine multiple interactionsEXP 6480464Carnitine inhibits the reaction [Doxorubicin results in decreased expression of FABP3 mRNA]CTDPMID:20470772
Fabp3Rat1,1-dichloroethene decreases expressionISOFabp3 (Mus musculus)6480464vinylidene chloride results in decreased expression of FABP3 mRNACTDPMID:26682919
Fabp3Rat1,2-dimethylhydrazine multiple interactionsISOFabp3 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FABP3 mRNACTDPMID:22206623
Fabp3Rat1,3,4-thiadiazole affects expressionEXP 64804641 more ...CTDPMID:30905023
Fabp3Rat11-deoxycorticosterone multiple interactionsEXP 6480464[Desoxycorticosterone co-treated with Sodium Chloride more ...CTDPMID:21135038
Fabp3Rat17alpha-ethynylestradiol multiple interactionsISOFabp3 (Mus musculus)6480464[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of FABP3 mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FABP3 mRNACTDPMID:17942748 and PMID:37844793
Fabp3Rat17alpha-ethynylestradiol decreases expressionISOFabp3 (Mus musculus)6480464Ethinyl Estradiol results in decreased expression of FABP3 mRNACTDPMID:17555576
Fabp3Rat17beta-estradiol decreases expressionISOFabp3 (Mus musculus)6480464Estradiol results in decreased expression of FABP3 mRNACTDPMID:19484750
Fabp3Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOFabp3 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FABP3 mRNACTDPMID:17942748
Fabp3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of FABP3 mRNACTDPMID:32109520
Fabp3Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOFabp3 (Mus musculus)64804642 more ...CTDPMID:38648751
Fabp3Rat2,4-dinitrotoluene decreases expressionISOFabp3 (Mus musculus)64804642 and 4-dinitrotoluene results in decreased expression of FABP3 mRNACTDPMID:24893713
Fabp3Rat2-Ethylhexanoic acid increases expressionEXP 64804642-ethylhexanoic acid results in increased expression of FABP3 mRNA and 2-ethylhexanoic acid results in increased expression of FABP3 proteinCTDPMID:15647598
Fabp3Rat2-palmitoylglycerol increases expressionISOFABP3 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of FABP3 mRNACTDPMID:37199045
Fabp3Rat3,5-diethoxycarbonyl-1,4-dihydrocollidine decreases expressionISOFabp3 (Mus musculus)64804643 more ...CTDPMID:20512997
Fabp3Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOFabp3 (Mus musculus)6480464[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP3 mRNACTDPMID:23428407
Fabp3Rat4,4'-sulfonyldiphenol increases expressionISOFABP3 (Homo sapiens)6480464bisphenol S results in increased expression of FABP3 mRNA and bisphenol S results in increased expression of FABP3 proteinCTDPMID:27685785 and PMID:34186270
Fabp3Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of FABP3 mRNACTDPMID:36041667

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Biological Process
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Fabp3Ratbrown fat cell differentiation acts_upstream_of_or_withinISOFabp3 (Mus musculus)1624291 PMID:28763438RGDPMID:28763438
Fabp3Ratbrown fat cell differentiation acts_upstream_of_or_withinIEAUniProtKB:P11404 and ensembl:ENSMUSP000000707091600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratcholesterol homeostasis involved_inISOFabp3 (Mus musculus)1624291 PMID:15835924RGDPMID:15835924
Fabp3Ratcholesterol homeostasis involved_inIEAUniProtKB:P11404 and ensembl:ENSMUSP000000707091600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratfatty acid beta-oxidation  NAS 728828 RGD 
Fabp3Ratfatty acid metabolic process  IEP 728828 RGD 
Fabp3Ratintracellular lipid transport involved_inISOFabp3 (Mus musculus)1624291 PMID:10224224 and PMID:15835924RGDPMID:10224224 and PMID:15835924
Fabp3Ratintracellular lipid transport involved_inIEAUniProtKB:P11404 and ensembl:ENSMUSP000000707091600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratlong-chain fatty acid transport  IDA 1582409 RGD 
Fabp3Ratlong-chain fatty acid transport involved_inIEAUniProtKB:P11404 and ensembl:ENSMUSP000000707091600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratlong-chain fatty acid transport involved_inIBAMGI:95476 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fabp3Ratlong-chain fatty acid transport involved_inISOFabp3 (Mus musculus)1624291 PMID:10224224 and PMID:15835924RGDPMID:10224224 and PMID:15835924
Fabp3Ratphospholipid homeostasis involved_inISOFabp3 (Mus musculus)1624291 PMID:15835924RGDPMID:15835924
Fabp3Ratphospholipid homeostasis involved_inIEAUniProtKB:P11404 and ensembl:ENSMUSP000000707091600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratpositive regulation of long-chain fatty acid import into cell involved_inISOFabp3 (Mus musculus)1624291 PMID:10224224 and PMID:15835924RGDPMID:10224224 and PMID:15835924
Fabp3Ratpositive regulation of long-chain fatty acid import into cell involved_inIEAUniProtKB:P11404 and ensembl:ENSMUSP000000707091600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratregulation of fatty acid oxidation involved_inISOFabp3 (Mus musculus)1624291 PMID:10224224RGDPMID:10224224
Fabp3Ratregulation of fatty acid oxidation involved_inIEAUniProtKB:P11404 and ensembl:ENSMUSP000000707091600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratregulation of phosphatidylcholine biosynthetic process acts_upstream_of_or_withinISOFabp3 (Mus musculus)1624291MGI:101790 PMID:15164767RGDPMID:15164767
Fabp3Ratregulation of phosphatidylcholine biosynthetic process acts_upstream_of_or_withinIEAUniProtKB:P11404 and ensembl:ENSMUSP000000707091600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Original Reference(s)
Fabp3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Fabp3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Fabp3Ratcytosol is_active_inIBAMGI:101790 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fabp3Ratextracellular space located_inISOFABP3 (Homo sapiens)1624291 PMID:23141496RGDPMID:23141496
Fabp3Ratextracellular space located_inIEAUniProtKB:P11404 and ensembl:ENSMUSP000000707091600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratextracellular space located_inISOFabp3 (Mus musculus)1624291 PMID:23141496RGDPMID:23141496
Fabp3Ratextracellular space located_inIEAUniProtKB:P05413 and ensembl:ENSP000003628171600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratnucleus is_active_inIBAMGI:101790 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fabp3Ratsarcoplasm  IDA 1582411 RGD 
Fabp3Ratsarcoplasmic reticulum NOTIDA 1582411 RGD 
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Molecular Function
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Original Reference(s)
Fabp3Ratcytoskeletal protein binding enablesISOFABP3 (Homo sapiens)1624291UniProtKB:O76041 and PMID:17987659RGDPMID:17987659
Fabp3Ratcytoskeletal protein binding enablesIEAUniProtKB:P05413 and ensembl:ENSP000003628171600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratfatty acid binding  TAS 728828 RGD 
Fabp3Ratfatty acid binding  IPICHEBI:298891582409 RGD 
Fabp3Ratfatty acid binding  IPIoctadecanoate1582408 RGD 
Fabp3Raticosatetraenoic acid binding  IPIHETE1582405 RGD 
Fabp3Ratlipid binding enablesIEAInterPro:IPR000463 and InterPro:IPR0312591600115GO_REF:0000002InterProGO_REF:0000002
Fabp3Ratlipid binding enablesIEAUniProtKB-KW:KW-04461600115GO_REF:0000043UniProtGO_REF:0000043
Fabp3Ratlong-chain fatty acid binding enablesISOFABP3 (Homo sapiens)1624291 PMID:3421901RGDPMID:3421901
Fabp3Ratlong-chain fatty acid binding enablesIBAPANTHER:PTN008531475 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fabp3Ratlong-chain fatty acid binding enablesIEAUniProtKB:P05413 and ensembl:ENSP000003628171600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratlong-chain fatty acid transmembrane transporter activity  IPICHEBI:298891582409 RGD 
Fabp3Ratoleic acid binding enablesISOFABP3 (Homo sapiens)1624291 PMID:3421901RGDPMID:3421901
Fabp3Ratoleic acid binding enablesIEAUniProtKB:P05413 and ensembl:ENSP000003628171600115GO_REF:0000107EnsemblGO_REF:0000107
Fabp3Ratprotein binding enablesISOFABP3 (Homo sapiens)1624291UniProtKB:A0MZ66 more ...RGDPMID:21516116 more ...
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RGD Manual Annotations


  
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Original Reference(s)
Fabp3Ratintegrin mediated signaling pathway   ISOFABP3 (Homo sapiens)7364738 RGD 

Imported Annotations - KEGG (archival)

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Original Reference(s)
Fabp3Rateicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma  IEA 6907045 KEGGrno:03320

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#
Reference Title
Reference Citation
1. Integrin inactivators: balancing cellular functions in vitro and in vivo. Bouvard D, etal., Nat Rev Mol Cell Biol. 2013 Jul;14(7):430-42. doi: 10.1038/nrm3599. Epub 2013 May 30.
2. Heart type fatty acid binding protein (H-FABP) is decreased in brains of patients with Down syndrome and Alzheimer's disease. Cheon MS, etal., J Neural Transm Suppl. 2003;(67):225-34.
3. Cloning and tissue distribution of rat heart fatty acid binding protein mRNA: identical forms in heart and skeletal muscle. Claffey KP, etal., Biochemistry 1987 Dec 1;26(24):7900-4.
4. Measurement of rat heart fatty acid binding protein by ELISA. Tissue distribution, developmental changes and subcellular distribution. Crisman TS, etal., J Mol Cell Cardiol. 1987 May;19(5):423-31.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Purification and characterization of fatty-acid-binding proteins from rat heart and liver. Glatz JF, etal., Biochim Biophys Acta. 1985 Oct 23;837(1):57-66.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Role of portal region lysine residues in electrostatic interactions between heart fatty acid binding protein and phospholipid membranes. Herr FM, etal., Biochemistry. 1996 Jan 30;35(4):1296-303.
9. Analysis of the tissue-specific expression, developmental regulation, and linkage relationships of a rodent gene encoding heart fatty acid binding protein. Heuckeroth RO, etal., J Biol Chem 1987 Jul 15;262(20):9709-17.
10. Mechanism of free fatty acid transfer from rat heart fatty acid-binding protein to phospholipid membranes. Evidence for a collisional process. Kim HK and Storch J, J Biol Chem. 1992 Oct 5;267(28):20051-6.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Characterization of a fatty acid-binding protein from rat heart. Offner GD, etal., J Biol Chem. 1986 Apr 25;261(12):5584-9.
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. Fatty acid-dependent expression of the muscle FABP gene - comparative analysis of gene control in functionally related, but evolutionary distant animal systems. Qu H, etal., Mol Cell Biochem. 2007 May;299(1-2):45-53.
16. GOA pipeline RGD automated data pipeline
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Equilibrium constants for the binding of fatty acids with fatty acid-binding proteins from adipocyte, intestine, heart, and liver measured with the fluorescent probe ADIFAB. Richieri GV, etal., J Biol Chem. 1994 Sep 30;269(39):23918-30.
19. Molecular mechanisms of diabetes reversibility after bariatric surgery. Rosa G, etal., Int J Obes (Lond). 2007 Sep;31(9):1429-36. Epub 2007 May 22.
20. Rat heart fatty acid-binding protein is highly homologous to the murine adipocyte 422 protein and the P2 protein of peripheral nerve myelin. Sacchettini JC, etal., J Biol Chem. 1986 Jun 25;261(18):8218-23.
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PMID:2005132   PMID:2775193   PMID:2806260   PMID:3162235   PMID:3415652   PMID:3421901   PMID:8117746   PMID:10224224   PMID:15164767   PMID:15835924   PMID:16502470   PMID:17987659  
PMID:19056867   PMID:20375122   PMID:21099311   PMID:21155221   PMID:23141496   PMID:23376485   PMID:23533145   PMID:26316108   PMID:26590355   PMID:28763438   PMID:34142475   PMID:34866110  
PMID:35509154  



Fabp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85147,936,027 - 147,942,870 (+)NCBIGRCr8
mRatBN7.25142,651,962 - 142,658,707 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5142,651,956 - 142,658,718 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5145,351,237 - 145,357,980 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05147,121,043 - 147,127,786 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05147,118,434 - 147,125,177 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05148,528,854 - 148,535,597 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5148,528,725 - 148,535,565 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05152,246,250 - 152,252,993 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45149,340,525 - 149,347,268 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15149,350,578 - 149,357,307 (+)NCBI
Celera5141,118,398 - 141,125,141 (+)NCBICelera
Cytogenetic Map5q36NCBI
FABP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38131,359,588 - 31,373,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl131,365,253 - 31,376,850 (-)EnsemblGRCh38hg38GRCh38
GRCh37131,838,100 - 31,845,923 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36131,610,687 - 31,618,510 (-)NCBINCBI36Build 36hg18NCBI36
Build 34131,507,593 - 31,514,985NCBI
Celera130,094,670 - 30,102,486 (-)NCBICelera
Cytogenetic Map1p35.2NCBI
HuRef129,944,876 - 29,952,692 (-)NCBIHuRef
CHM1_1131,954,007 - 31,961,831 (-)NCBICHM1_1
T2T-CHM13v2.0131,211,868 - 31,225,340 (-)NCBIT2T-CHM13v2.0
Fabp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394130,202,531 - 130,209,256 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4130,202,388 - 130,209,256 (+)EnsemblGRCm39 Ensembl
GRCm384130,308,738 - 130,315,463 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4130,308,595 - 130,315,463 (+)EnsemblGRCm38mm10GRCm38
MGSCv374129,986,022 - 129,992,707 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364129,811,082 - 129,817,767 (+)NCBIMGSCv36mm8
Celera4128,641,729 - 128,648,414 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map463.43NCBI
Fabp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554529,846,689 - 9,861,971 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554529,851,182 - 9,858,735 (-)NCBIChiLan1.0ChiLan1.0
FABP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21195,456,558 - 195,473,533 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11194,579,251 - 194,592,583 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0130,640,595 - 30,653,450 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1131,660,924 - 31,673,689 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl131,665,270 - 31,673,689 (-)Ensemblpanpan1.1panPan2
FABP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1269,651,140 - 69,659,082 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl269,650,322 - 69,658,443 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha266,229,601 - 66,237,545 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0270,215,389 - 70,223,333 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl270,214,573 - 70,226,198 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1267,051,318 - 67,059,262 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0268,048,008 - 68,055,952 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0269,047,575 - 69,055,518 (+)NCBIUU_Cfam_GSD_1.0
Fabp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505848,751,795 - 48,760,226 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647414,574,891 - 14,585,706 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647414,576,582 - 14,584,362 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FABP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl687,942,790 - 87,951,610 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1687,943,003 - 87,950,708 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2681,714,138 - 81,715,645 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FABP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120101,464,899 - 101,472,223 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20101,464,960 - 101,474,350 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603315,202,100 - 15,209,969 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fabp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476414,698,062 - 14,705,972 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476414,698,062 - 14,705,379 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Fabp3
48 total Variants

Predicted Target Of
Summary Value
Count of predictions:143
Count of miRNA genes:98
Interacting mature miRNAs:106
Transcripts:ENSRNOT00000017325
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 41 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5129132428143070159Rat

1 to 10 of 41 rows
RH129910  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25142,651,053 - 142,651,259 (+)MAPPERmRatBN7.2
Rnor_6.05148,527,946 - 148,528,151NCBIRnor6.0
Rnor_5.05152,245,342 - 152,245,547UniSTSRnor5.0
RGSC_v3.45149,339,617 - 149,339,822UniSTSRGSC3.4
Celera5141,117,490 - 141,117,695UniSTS
Cytogenetic Map5q36UniSTS
RH134427  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25142,658,732 - 142,658,918 (+)MAPPERmRatBN7.2
Rnor_6.05148,535,625 - 148,535,810NCBIRnor6.0
Rnor_5.05152,253,021 - 152,253,206UniSTSRnor5.0
RGSC_v3.45149,347,296 - 149,347,481UniSTSRGSC3.4
Celera5141,125,169 - 141,125,354UniSTS
RH 3.4 Map5990.09UniSTS
Cytogenetic Map5q36UniSTS
RH94406  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25142,658,522 - 142,658,702 (+)MAPPERmRatBN7.2
mRatBN7.2515,110,318 - 15,110,494 (+)MAPPERmRatBN7.2
Rnor_6.0514,994,377 - 14,994,552NCBIRnor6.0
Rnor_6.05148,535,415 - 148,535,594NCBIRnor6.0
Rnor_5.0519,778,456 - 19,778,631UniSTSRnor5.0
Rnor_5.05152,252,811 - 152,252,990UniSTSRnor5.0
RGSC_v3.45149,347,086 - 149,347,265UniSTSRGSC3.4
RGSC_v3.4515,336,448 - 15,336,623UniSTSRGSC3.4
Celera514,492,133 - 14,492,308UniSTS
Celera5141,124,959 - 141,125,138UniSTS
Cytogenetic Map5q36UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000017325   ⟹   ENSRNOP00000017325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5142,651,956 - 142,658,718 (+)Ensembl
Rnor_6.0 Ensembl5148,528,725 - 148,535,565 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109377   ⟹   ENSRNOP00000084646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5142,651,956 - 142,657,944 (+)Ensembl
RefSeq Acc Id: NM_024162   ⟹   NP_077076
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85147,936,125 - 147,942,868 (+)NCBI
mRatBN7.25142,651,962 - 142,658,705 (+)NCBI
Rnor_6.05148,528,854 - 148,535,597 (+)NCBI
Rnor_5.05152,246,250 - 152,252,993 (+)NCBI
RGSC_v3.45149,340,525 - 149,347,268 (+)RGD
Celera5141,118,398 - 141,125,141 (+)RGD
Sequence:
RefSeq Acc Id: XM_063288462   ⟹   XP_063144532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85147,936,027 - 147,942,870 (+)NCBI
Protein RefSeqs NP_077076 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144532 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41136 (Get FASTA)   NCBI Sequence Viewer  
  AAA41137 (Get FASTA)   NCBI Sequence Viewer  
  EDL80590 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017325
  ENSRNOP00000017325.2
GenBank Protein P07483 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_077076   ⟸   NM_024162
- UniProtKB: Q9QY04 (UniProtKB/Swiss-Prot),   P07483 (UniProtKB/Swiss-Prot),   A6ISN9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017325   ⟸   ENSRNOT00000017325
Ensembl Acc Id: ENSRNOP00000084646   ⟸   ENSRNOT00000109377
RefSeq Acc Id: XP_063144532   ⟸   XM_063288462
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2E9 (UniProtKB/TrEMBL)
Name Modeler Protein Id AA Range Protein Structure
AF-P07483-F1-model_v2 AlphaFold P07483 1-133 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694082
Promoter ID:EPDNEW_R4607
Type:single initiation site
Name:Fabp3_1
Description:fatty acid binding protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05148,528,850 - 148,528,910EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-39751 BioCyc
BioCyc Pathway PWY-6318 [L-phenylalanine degradation IV (mammalian, via side chain)] BioCyc
BioCyc Pathway Image PWY-6318 BioCyc
Ensembl Genes ENSRNOG00000012879 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017325 ENTREZGENE
  ENSRNOT00000017325.6 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.128.20 UniProtKB/Swiss-Prot
InterPro Calycin UniProtKB/Swiss-Prot
  Fatty_acid-bd UniProtKB/Swiss-Prot
  ILBP UniProtKB/Swiss-Prot
  Lipocln_cytosolic_FA-bd_dom UniProtKB/Swiss-Prot
KEGG Report rno:79131 UniProtKB/Swiss-Prot
NCBI Gene 79131 ENTREZGENE
PANTHER PTHR11955 UniProtKB/Swiss-Prot
Pfam Lipocalin UniProtKB/Swiss-Prot
PhenoGen Fabp3 PhenoGen
PRINTS FATTYACIDBP UniProtKB/Swiss-Prot
PROSITE FABP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012879 RatGTEx
Superfamily-SCOP SSF50814 UniProtKB/Swiss-Prot
UniProt A0A8I6A2E9 ENTREZGENE, UniProtKB/TrEMBL
  A6ISN9 ENTREZGENE, UniProtKB/TrEMBL
  FABPH_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9QY04 ENTREZGENE
UniProt Secondary Q9QY04 UniProtKB/Swiss-Prot
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Fabp3  fatty acid binding protein 3  Fabp3  fatty acid binding protein 3, muscle and heart  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Fabp3  fatty acid binding protein 3, muscle and heart  Fabp3  fatty acid binding protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Fabp3  fatty acid binding protein 3      Name updated 70584 APPROVED

Note Type Note Reference