Kcnd3 (potassium voltage-gated channel, Shal-related family, member 3) - Rat Genome Database

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Gene: Kcnd3 (potassium voltage-gated channel, Shal-related family, member 3) Mus musculus
Analyze
Symbol: Kcnd3
Name: potassium voltage-gated channel, Shal-related family, member 3
RGD ID: 68577
MGI Page MGI
Description: Predicted to enable A-type (transient outward) potassium channel activity and transmembrane transporter binding activity. Predicted to contribute to voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Predicted to be involved in several processes, including cellular response to BMP stimulus; potassium ion transmembrane transport; and regulation of heart rate by cardiac conduction. Predicted to act upstream of or within potassium ion transmembrane transport. Located in membrane. Is active in GABA-ergic synapse and postsynaptic specialization membrane. Is expressed in heart and heart ventricle. Human ortholog(s) of this gene implicated in Brugada syndrome 9 and spinocerebellar ataxia type 19/22. Orthologous to human KCND3 (potassium voltage-gated channel subfamily D member 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AW045978; Kncd3; Kv4.; Kv4.3; potassium channel Kv4.3L; potassium channel Kv4.3M; potassium voltage-gated channel subfamily D member 3; voltage-gated potassium channel subunit Kv4.3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393105,359,206 - 105,581,318 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3105,359,646 - 105,581,318 (+)EnsemblGRCm39 Ensembl
GRCm383105,451,890 - 105,674,002 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3105,452,330 - 105,674,002 (+)EnsemblGRCm38mm10GRCm38
MGSCv373105,255,248 - 105,476,920 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363105,580,386 - 105,802,058 (+)NCBIMGSCv36mm8
Celera3107,640,899 - 107,862,899 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map346.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4-aminopyridine  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chelerythrine  (ISO)
clothianidin  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
decabromodiphenyl ether  (ISO)
diallyl trisulfide  (ISO)
dimethylarsinic acid  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
fenvalerate  (ISO)
ferrostatin-1  (EXP)
fluoxetine  (ISO)
fulvestrant  (ISO)
genistein  (EXP)
glufosinate  (EXP)
lipopolysaccharide  (ISO)
maneb  (EXP)
methapyrilene  (ISO)
methoxychlor  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nitrofen  (ISO)
O-methyleugenol  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PCB138  (EXP)
phenylephrine  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pioglitazone  (EXP)
progesterone  (EXP)
raloxifene  (ISO)
reserpine  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
tamoxifen  (ISO)
testosterone  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
verapamil  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
excitatory synaptic transmission pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
long term potentiation  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Kv4 potassium channel subunits control action potential repolarization and frequency-dependent broadening in rat hippocampal CA1 pyramidal neurones. Kim J, etal., J Physiol. 2005 Nov 15;569(Pt 1):41-57. Epub 2005 Sep 1.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Bone morphogenetic protein-4 contributes to the down-regulation of Kv4.3 K+ channels in pathological cardiac hypertrophy. Sun B, etal., Biochem Biophys Res Commun. 2013 Jul 12;436(4):591-4. doi: 10.1016/j.bbrc.2013.05.113. Epub 2013 Jun 6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10479680   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11598014   PMID:11909823   PMID:12088861   PMID:12466851   PMID:12477932  
PMID:15662035   PMID:16141072   PMID:16141073   PMID:16239150   PMID:16556864   PMID:16985003   PMID:17122053   PMID:18045613   PMID:18364020   PMID:18371079   PMID:18603586   PMID:18678642  
PMID:19109250   PMID:19608983   PMID:20006971   PMID:20371829   PMID:20943905   PMID:21677750   PMID:21873635   PMID:22357600   PMID:22615428   PMID:22815518   PMID:23542581   PMID:24516526  
PMID:25297088   PMID:25775569   PMID:25798587   PMID:26152125   PMID:26196737   PMID:26205295   PMID:26311767   PMID:26378152   PMID:28646025   PMID:31248728   PMID:32109384   PMID:32325033  
PMID:34386734   PMID:34432539   PMID:34815492   PMID:36417873   PMID:37873566   PMID:38187761  


Genomics

Comparative Map Data
Kcnd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393105,359,206 - 105,581,318 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3105,359,646 - 105,581,318 (+)EnsemblGRCm39 Ensembl
GRCm383105,451,890 - 105,674,002 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3105,452,330 - 105,674,002 (+)EnsemblGRCm38mm10GRCm38
MGSCv373105,255,248 - 105,476,920 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363105,580,386 - 105,802,058 (+)NCBIMGSCv36mm8
Celera3107,640,899 - 107,862,899 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map346.32NCBI
KCND3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381111,770,662 - 111,989,668 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1111,770,662 - 111,989,668 (-)EnsemblGRCh38hg38GRCh38
GRCh371112,313,284 - 112,532,290 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361112,119,977 - 112,333,300 (-)NCBINCBI36Build 36hg18NCBI36
Build 341112,030,495 - 112,243,819NCBI
Celera1110,565,074 - 110,778,378 (-)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1110,189,856 - 110,403,378 (-)NCBIHuRef
CHM1_11112,433,439 - 112,646,758 (-)NCBICHM1_1
T2T-CHM13v2.01111,785,561 - 112,004,582 (-)NCBIT2T-CHM13v2.0
Kcnd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82195,626,316 - 195,843,690 (+)NCBIGRCr8
mRatBN7.22192,937,950 - 193,155,345 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2192,937,950 - 193,155,345 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2200,532,308 - 200,749,767 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02198,418,563 - 198,635,769 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02193,235,506 - 193,452,721 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02207,923,775 - 208,140,727 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2207,923,775 - 208,140,727 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02227,345,052 - 227,561,680 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42200,709,778 - 200,924,575 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13128,828,320 - 128,840,436 (+)NCBI
Celera2185,602,165 - 185,617,489 (+)NCBICelera
Cytogenetic Map2q34NCBI
Kcnd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543515,227,615 - 15,431,190 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543515,227,386 - 15,431,136 (-)NCBIChiLan1.0ChiLan1.0
KCND3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21115,037,963 - 115,255,901 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11114,185,438 - 114,404,074 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01114,433,203 - 114,651,894 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11125,702,654 - 125,910,075 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1125,696,907 - 125,909,814 (+)Ensemblpanpan1.1panPan2
KCND3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11763,470,829 - 63,668,354 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1763,470,415 - 63,668,035 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1762,986,103 - 63,182,211 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01764,647,680 - 64,841,597 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1764,637,936 - 64,841,028 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11763,378,372 - 63,574,346 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01763,437,366 - 63,633,850 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01764,235,078 - 64,431,380 (+)NCBIUU_Cfam_GSD_1.0
Kcnd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505816,850,374 - 17,059,824 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936690422,883 - 621,308 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936690417,907 - 627,025 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCND3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4108,246,237 - 108,621,510 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14108,394,687 - 108,621,514 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24118,542,614 - 118,763,673 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCND3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12021,618,365 - 21,833,443 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2021,625,147 - 21,833,186 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603836,641,070 - 36,861,725 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247727,484,632 - 7,693,329 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247727,482,462 - 7,694,316 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kcnd3
6805 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2679
Count of miRNA genes:863
Interacting mature miRNAs:1235
Transcripts:ENSMUST00000079169, ENSMUST00000098761, ENSMUST00000118360, ENSMUST00000141694, ENSMUST00000147209
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390376936124377072Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390378017124378017Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391000105125008748Mouse
1301349Pgia26_mproteoglycan induced arthritis 26 (mouse)Not determined392251533126251650Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
10043955Wt10q4_mbody weight, 10 weeks, QTL 4 (mouse)Not determined398624041132624197Mouse
11533920Mvb3_mmodifier of vibrator 3 (mouse)398635284132635383Mouse
12792984Modn1_mmodifier of Dstn neovascularization 1 (mouse)398635284132635383Mouse
1302114Tbs1_mtuberculosis severity 1 (mouse)Not determined398924105132924250Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
26884419Bzwq6_mbi-zygomatic width QTL 6, 10 week (mouse)3100607316137205761Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse
1301805Mors2_mmodifier of obesity related sterility 2 (mouse)Not determined3103482659137482783Mouse

Markers in Region
PMC125678P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383105,658,671 - 105,658,750UniSTSGRCm38
MGSCv373105,461,589 - 105,461,668UniSTSGRCm37
Celera3107,847,553 - 107,847,632UniSTS
Cytogenetic Map3F3UniSTS
AW045978  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383105,673,385 - 105,673,493UniSTSGRCm38
MGSCv373105,476,303 - 105,476,411UniSTSGRCm37
Celera3107,862,282 - 107,862,390UniSTS
Cytogenetic Map3F3UniSTS
Whitehead/MRC_RH31194.18UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001039347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC139316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02094929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF107781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF107782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW045689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY283095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000079169   ⟹   ENSMUSP00000078169
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3105,366,098 - 105,576,625 (+)Ensembl
GRCm38.p6 Ensembl3105,458,782 - 105,669,309 (+)Ensembl
RefSeq Acc Id: ENSMUST00000098761   ⟹   ENSMUSP00000096357
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3105,359,646 - 105,581,318 (+)Ensembl
GRCm38.p6 Ensembl3105,452,330 - 105,674,002 (+)Ensembl
RefSeq Acc Id: ENSMUST00000118360   ⟹   ENSMUSP00000113436
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3105,360,402 - 105,576,776 (+)Ensembl
GRCm38.p6 Ensembl3105,453,086 - 105,669,460 (+)Ensembl
RefSeq Acc Id: ENSMUST00000141694
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3105,359,889 - 105,574,905 (+)Ensembl
GRCm38.p6 Ensembl3105,452,573 - 105,667,589 (+)Ensembl
RefSeq Acc Id: ENSMUST00000147209
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3105,576,321 - 105,577,160 (+)Ensembl
GRCm38.p6 Ensembl3105,669,005 - 105,669,844 (+)Ensembl
RefSeq Acc Id: NM_001039347   ⟹   NP_001034436
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393105,359,206 - 105,581,318 (+)NCBI
GRCm383105,451,890 - 105,674,002 (+)NCBI
MGSCv373105,255,248 - 105,476,920 (+)RGD
Celera3107,640,899 - 107,862,899 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_019931   ⟹   NP_064315
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393105,359,206 - 105,581,318 (+)NCBI
GRCm383105,451,890 - 105,674,002 (+)NCBI
MGSCv373105,255,248 - 105,476,920 (+)RGD
Celera3107,640,899 - 107,862,899 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030252699   ⟹   XP_030108559
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393105,361,481 - 105,581,318 (+)NCBI
GRCm383105,457,353 - 105,674,002 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163174   ⟹   XP_036019067
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393105,359,479 - 105,427,583 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001034436   ⟸   NM_001039347
- Peptide Label: isoform 1 precursor
- UniProtKB: Q3UH54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_064315   ⟸   NM_019931
- Peptide Label: isoform 2 precursor
- UniProtKB: Q8CC44 (UniProtKB/Swiss-Prot),   Q9Z0V0 (UniProtKB/Swiss-Prot),   Q9Z0V1 (UniProtKB/Swiss-Prot),   B2RUE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030108559   ⟸   XM_030252699
- Peptide Label: isoform X1
- UniProtKB: Q9Z0V1 (UniProtKB/Swiss-Prot),   Q8CC44 (UniProtKB/Swiss-Prot),   Q9Z0V0 (UniProtKB/Swiss-Prot),   B2RUE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000096357   ⟸   ENSMUST00000098761
RefSeq Acc Id: ENSMUSP00000113436   ⟸   ENSMUST00000118360
RefSeq Acc Id: ENSMUSP00000078169   ⟸   ENSMUST00000079169
RefSeq Acc Id: XP_036019067   ⟸   XM_036163174
- Peptide Label: isoform X2
Protein Domains
BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z0V1-F1-model_v2 AlphaFold Q9Z0V1 1-655 view protein structure

Promoters
RGD ID:6881930
Promoter ID:EPDNEW_M4416
Type:initiation region
Name:Kcnd3_1
Description:Mus musculus potassium voltage-gated channel, Shal-related family,member 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383105,452,317 - 105,452,377EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1928743 AgrOrtholog
Ensembl Genes ENSMUSG00000040896 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000079169 ENTREZGENE
  ENSMUST00000079169.5 UniProtKB/Swiss-Prot
  ENSMUST00000098761 ENTREZGENE
  ENSMUST00000098761.10 UniProtKB/Swiss-Prot
  ENSMUST00000118360.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv4.3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv4_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Shal-type_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56543 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1928743 ENTREZGENE
NCBI Gene 56543 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11537 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF3399 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Shal-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB KCND3 RGD
PhenoGen Kcnd3 PhenoGen
PRINTS KCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KV43CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KVCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHALCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RUE0 ENTREZGENE, UniProtKB/TrEMBL
  KCND3_MOUSE UniProtKB/Swiss-Prot
  Q3UH54 ENTREZGENE, UniProtKB/TrEMBL
  Q8CC44 ENTREZGENE
  Q9Z0V0 ENTREZGENE
  Q9Z0V1 ENTREZGENE
UniProt Secondary Q8CC44 UniProtKB/Swiss-Prot
  Q9Z0V0 UniProtKB/Swiss-Prot