Kcnd2 (potassium voltage-gated channel, Shal-related family, member 2) - Rat Genome Database

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Gene: Kcnd2 (potassium voltage-gated channel, Shal-related family, member 2) Mus musculus
Analyze
Symbol: Kcnd2
Name: potassium voltage-gated channel, Shal-related family, member 2
RGD ID: 68575
MGI Page MGI
Description: Enables A-type (transient outward) potassium channel activity and voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in several processes, including locomotor rhythm; neuronal action potential; and potassium ion transmembrane transport. Located in dendritic spine; membrane; and neuronal cell body. Part of voltage-gated potassium channel complex. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic specialization membrane. Is expressed in several structures, including heart; hindlimb digit; metanephros; nervous system; and sensory organ. Orthologous to human KCND2 (potassium voltage-gated channel subfamily D member 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI839615; AW555701; Gm52855; Kv4.; Kv4.2; mKIAA1044; potassium channel Kv4.2; potassium voltage-gated channel subfamily D member 2; predicted gene, 52855; R75121; voltage-gated potassium channel subunit Kv4.2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39621,212,101 - 21,729,804 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl621,215,502 - 21,729,804 (+)EnsemblGRCm39 Ensembl
GRCm38621,215,346 - 21,729,805 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl621,215,503 - 21,729,805 (+)EnsemblGRCm38mm10GRCm38
MGSCv37621,166,109 - 21,679,805 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36621,166,110 - 21,679,806 (+)NCBIMGSCv36mm8
Celera621,270,473 - 21,783,671 (+)NCBICelera
Cytogenetic Map6A2- A3.1NCBI
cM Map68.49NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3',5'-cyclic AMP  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
aldrin  (EXP)
amiodarone  (EXP)
amitrole  (ISO)
antirheumatic drug  (ISO)
ATP  (ISO)
benzo[a]pyrene  (EXP)
beta-hexachlorocyclohexane  (EXP)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
carmustine  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cocaine  (ISO)
Cuprizon  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dichlorine  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
formaldehyde  (ISO)
furan  (ISO)
glucose  (ISO)
glyphosate  (ISO)
isoprenaline  (EXP)
lipopolysaccharide  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
miconazole  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
ochratoxin A  (ISO)
ouabain  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
PCB138  (EXP)
phenylephrine  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
pirinixic acid  (EXP)
potassium chloride  (ISO)
progesterone  (EXP,ISO)
rac-lactic acid  (ISO)
reserpine  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
scopolamine  (ISO)
serpentine asbestos  (ISO)
sulfadimethoxine  (ISO)
sulforaphane  (EXP)
testosterone  (ISO)
trichostatin A  (ISO)
triticonazole  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
alfentanil pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
excitatory synaptic transmission pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
long term potentiation  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Kv4 potassium channel subunits control action potential repolarization and frequency-dependent broadening in rat hippocampal CA1 pyramidal neurones. Kim J, etal., J Physiol. 2005 Nov 15;569(Pt 1):41-57. Epub 2005 Sep 1.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7905852   PMID:8835546   PMID:8889548   PMID:10349636   PMID:10432335   PMID:10479680   PMID:10571538   PMID:10700246   PMID:10922068   PMID:11040264   PMID:11042159   PMID:11076861  
PMID:11217851   PMID:11747815   PMID:11805342   PMID:11909823   PMID:12451113   PMID:12465718   PMID:12477932   PMID:12612193   PMID:14559911   PMID:15140189   PMID:15489334   PMID:15662035  
PMID:16008572   PMID:16009497   PMID:16141072   PMID:16141073   PMID:16239150   PMID:16257958   PMID:16293790   PMID:16426762   PMID:16600858   PMID:16602821   PMID:16923961   PMID:16985003  
PMID:17114649   PMID:17122038   PMID:17122039   PMID:17122053   PMID:17258352   PMID:17397913   PMID:17582333   PMID:17640927   PMID:18045912   PMID:18187474   PMID:18276729   PMID:18368112  
PMID:18371079   PMID:18495661   PMID:18566000   PMID:18603586   PMID:18708490   PMID:19038222   PMID:19145035   PMID:19453702   PMID:19538736   PMID:19703524   PMID:19713751   PMID:19906978  
PMID:20045463   PMID:20087888   PMID:20111592   PMID:20371829   PMID:20550966   PMID:20573902   PMID:20709747   PMID:20801198   PMID:20857488   PMID:20943905   PMID:21267068   PMID:21383190  
PMID:21490210   PMID:21677750   PMID:21873635   PMID:21943606   PMID:22098631   PMID:22099464   PMID:22235033   PMID:22311982   PMID:22505720   PMID:22514734   PMID:22539834   PMID:22615428  
PMID:22738428   PMID:22815518   PMID:22923619   PMID:22992950   PMID:23055512   PMID:23115188   PMID:23542581   PMID:23573265   PMID:23713033   PMID:23912628   PMID:24225951   PMID:24658003  
PMID:24859499   PMID:24952961   PMID:25190801   PMID:25332179   PMID:25798587   PMID:25878292   PMID:26152125   PMID:26196737   PMID:26311767   PMID:26378152   PMID:26494785   PMID:26980786  
PMID:27210758   PMID:27307045   PMID:27681419   PMID:27697822   PMID:28163158   PMID:28646025   PMID:29139549   PMID:29214635   PMID:29445148   PMID:29790931   PMID:30410445   PMID:31212067  
PMID:32209671   PMID:32218435   PMID:32822706   PMID:33443158   PMID:34321999   PMID:34384853   PMID:34386734   PMID:34795560   PMID:35681537   PMID:36417873   PMID:38187761  


Genomics

Comparative Map Data
Kcnd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39621,212,101 - 21,729,804 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl621,215,502 - 21,729,804 (+)EnsemblGRCm39 Ensembl
GRCm38621,215,346 - 21,729,805 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl621,215,503 - 21,729,805 (+)EnsemblGRCm38mm10GRCm38
MGSCv37621,166,109 - 21,679,805 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36621,166,110 - 21,679,806 (+)NCBIMGSCv36mm8
Celera621,270,473 - 21,783,671 (+)NCBICelera
Cytogenetic Map6A2- A3.1NCBI
cM Map68.49NCBI
KCND2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387120,272,908 - 120,750,337 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7120,273,175 - 120,750,337 (+)EnsemblGRCh38hg38GRCh38
GRCh377119,913,229 - 120,390,391 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367119,700,958 - 120,177,623 (+)NCBINCBI36Build 36hg18NCBI36
Build 347119,507,672 - 119,984,338NCBI
Celera7114,723,245 - 115,199,902 (+)NCBICelera
Cytogenetic Map7q31.31NCBI
HuRef7114,276,961 - 114,753,560 (+)NCBIHuRef
CHM1_17119,847,044 - 120,323,690 (+)NCBICHM1_1
T2T-CHM13v2.07121,573,495 - 122,065,688 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27119,308,832 - 119,785,474 (+)NCBI
Kcnd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8450,741,595 - 51,243,540 (+)NCBIGRCr8
mRatBN7.2449,775,812 - 50,277,746 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl449,776,246 - 50,277,728 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx454,749,390 - 55,256,964 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0450,670,509 - 51,178,050 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0449,094,034 - 49,606,328 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0448,309,283 - 48,816,804 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0448,099,455 - 48,609,215 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4447,541,787 - 48,047,924 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1447,772,679 - 48,277,046 (+)NCBI
Celera444,984,114 - 45,483,230 (+)NCBICelera
Cytogenetic Map4q22NCBI
Kcnd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554792,062,608 - 2,543,125 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554792,062,607 - 2,545,576 (+)NCBIChiLan1.0ChiLan1.0
KCND2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26157,137,701 - 157,618,726 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan179,147,110 - 9,628,983 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07112,277,018 - 112,751,896 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17124,965,851 - 125,439,913 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7124,966,816 - 125,437,430 (+)Ensemblpanpan1.1panPan2
LOC607881
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1460,421,540 - 60,422,657 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.014126,284 - 155,942 (+)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.01468,634 - 98,256 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01449,808 - 79,444 (+)NCBIUU_Cfam_GSD_1.0
Kcnd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511847,376,410 - 47,833,708 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366054,372,671 - 4,825,423 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366054,370,222 - 4,828,972 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCND2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1826,139,457 - 26,623,233 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11826,139,457 - 26,624,210 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21827,744,043 - 27,759,304 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCND2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12189,091,939 - 89,575,464 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604214,004,421 - 14,488,070 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478315,351,870 - 15,891,057 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478315,349,416 - 15,892,011 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kcnd2
17701 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:729
Count of miRNA genes:410
Interacting mature miRNAs:519
Transcripts:ENSMUST00000081542
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301178Lith10_mlithogenic gene 10 (mouse)Not determined6121465015Mouse
10043884Bhr8_mbronchial hyperresponsiveness 8 (mouse)Not determined6121465015Mouse
10044000Mobq9_mmultigenetic obesity QTL 9 (mouse)Not determined6121465015Mouse
1357503Nhdlq5_mnon-HDL QTL 5 (mouse)Not determined6121465015Mouse
12904934Edlmmq4_mextensor digitorum longus muscle mass QTL 4 (mouse)6125514064Mouse
12904942Tammq3_mtibialis anterior muscle mass QTL 3 (mouse)6125514064Mouse
12904955Gmmq3_mgastrocnemius muscle mass QTL 3 (mouse)6125514064Mouse
1301131Chol2_mcholesterol 2 (mouse)Not determined6132144495Mouse
5491191Mobq2_mmultigenic obesity QTL 2 (mouse)Not determined6132144495Mouse
1302024Skull7_mskull morphology 7 (mouse)Not determined6132144495Mouse
15039372Nmrs22_mNAFLD-associated magnetic resonance shift 22 (mouse)6147633435476334Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1300731Smdq3_msegregation of mitochondrial DNA QTL 3 (mouse)Not determined6424920638249325Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
11353836Bmiq1_mbody mass index QTL 1 (mouse)6450382329751333Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345291115Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707443297168Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797146118069Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122146751333Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122146751333Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse

Markers in Region
RH132271  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,729,309 - 21,729,498UniSTSGRCm38
MGSCv37621,679,309 - 21,679,498UniSTSGRCm37
Celera621,783,175 - 21,783,364UniSTS
Cytogenetic Map6A2-A3.1UniSTS
AI848395  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,235,979 - 21,236,128UniSTSGRCm38
MGSCv37621,185,979 - 21,186,128UniSTSGRCm37
Celera621,290,288 - 21,290,437UniSTS
Cytogenetic Map6A2-A3.1UniSTS
AI839615  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,729,471 - 21,729,618UniSTSGRCm38
MGSCv37621,679,471 - 21,679,618UniSTSGRCm37
Celera621,783,337 - 21,783,484UniSTS
Cytogenetic Map6A2-A3.1UniSTS
Whitehead/MRC_RH6149.12UniSTS
AW555701  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,729,149 - 21,729,289UniSTSGRCm38
MGSCv37621,679,149 - 21,679,289UniSTSGRCm37
Celera621,783,015 - 21,783,155UniSTS
Cytogenetic Map6A2-A3.1UniSTS
Whitehead/MRC_RH6149.48UniSTS
AW554807  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,235,674 - 21,235,768UniSTSGRCm38
MGSCv37621,185,674 - 21,185,768UniSTSGRCm37
Celera621,289,983 - 21,290,077UniSTS
Cytogenetic Map6A2-A3.1UniSTS
37.MMHAP37FRE10.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,727,337 - 21,727,524UniSTSGRCm38
MGSCv37621,677,337 - 21,677,524UniSTSGRCm37
Celera621,781,203 - 21,781,390UniSTS
Cytogenetic Map6A2-A3.1UniSTS
Whitehead_YAC6 UniSTS
MDB1071  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,729,599 - 21,729,754UniSTSGRCm38
MGSCv37621,679,599 - 21,679,754UniSTSGRCm37
Celera621,783,465 - 21,783,620UniSTS
Cytogenetic Map6A2-A3.1UniSTS
Whitehead_YAC6 UniSTS
D6Mit266  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,249,207 - 21,249,326UniSTSGRCm38
MGSCv37621,199,207 - 21,199,326UniSTSGRCm37
Celera621,303,459 - 21,303,578UniSTS
Cytogenetic Map6A2-A3.1UniSTS
cM Map63.6UniSTS
Whitehead Genetic63.3UniSTS
Whitehead_YAC6 UniSTS
D6Mit306  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,480,933 - 21,481,056UniSTSGRCm38
MGSCv37621,430,933 - 21,431,056UniSTSGRCm37
Celera621,534,791 - 21,534,914UniSTS
Cytogenetic Map6A2-A3.1UniSTS
cM Map63.6UniSTS
Whitehead Genetic63.3UniSTS
Whitehead_YAC6 UniSTS
RH125168  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,729,590 - 21,729,740UniSTSGRCm38
MGSCv37621,679,590 - 21,679,740UniSTSGRCm37
Celera621,783,456 - 21,783,606UniSTS
Cytogenetic Map6A2-A3.1UniSTS
Kcnd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38621,726,071 - 21,727,236UniSTSGRCm38
MGSCv37621,676,071 - 21,677,236UniSTSGRCm37
Celera621,779,937 - 21,781,102UniSTS
Cytogenetic Map6A2-A3.1UniSTS
cM Map67.2UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036165884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003956270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB045326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB093280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC117233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC127311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC130721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC149089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC165965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF107780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY279027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB520748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000081542   ⟹   ENSMUSP00000080257
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl621,215,502 - 21,729,804 (+)Ensembl
GRCm38.p6 Ensembl621,215,503 - 21,729,805 (+)Ensembl
RefSeq Acc Id: NM_019697   ⟹   NP_062671
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39621,215,345 - 21,729,804 (+)NCBI
GRCm38621,215,346 - 21,729,805 (+)NCBI
MGSCv37621,166,109 - 21,679,805 (+)RGD
Celera621,270,473 - 21,783,671 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036165884   ⟹   XP_036021777
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39621,212,101 - 21,675,126 (+)NCBI
Sequence:
RefSeq Acc Id: NP_062671   ⟸   NM_019697
- Peptide Label: precursor
- UniProtKB: Q8CHB7 (UniProtKB/Swiss-Prot),   Q8BSK3 (UniProtKB/Swiss-Prot),   Q9JJ60 (UniProtKB/Swiss-Prot),   Q9Z0V2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000080257   ⟸   ENSMUST00000081542
RefSeq Acc Id: XP_036021777   ⟸   XM_036165884
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z0V2-F1-model_v2 AlphaFold Q9Z0V2 1-630 view protein structure

Promoters
RGD ID:6839529
Promoter ID:MM_KWN:45262
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_019697
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36621,165,221 - 21,165,721 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102663 AgrOrtholog
Ensembl Genes ENSMUSG00000060882 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000081542 ENTREZGENE
  ENSMUST00000081542.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot
  1.20.120.350 UniProtKB/Swiss-Prot
InterPro BTB/POZ_dom UniProtKB/Swiss-Prot
  Ion_trans_dom UniProtKB/Swiss-Prot
  K_chnl_volt-dep_Kv UniProtKB/Swiss-Prot
  K_chnl_volt-dep_Kv4 UniProtKB/Swiss-Prot
  K_chnl_volt-dep_Kv4.2 UniProtKB/Swiss-Prot
  K_chnl_volt-dep_Kv4_C UniProtKB/Swiss-Prot
  Shal-type_N UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
  T1-type_BTB UniProtKB/Swiss-Prot
  Volt_channel_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:16508 UniProtKB/Swiss-Prot
MGD MGI:102663 ENTREZGENE
NCBI Gene 16508 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 2 UniProtKB/Swiss-Prot
  PTHR11537 UniProtKB/Swiss-Prot
Pfam BTB_2 UniProtKB/Swiss-Prot
  DUF3399 UniProtKB/Swiss-Prot
  Ion_trans UniProtKB/Swiss-Prot
  Shal-type UniProtKB/Swiss-Prot
PhenoGen Kcnd2 PhenoGen
PRINTS KCHANNEL UniProtKB/Swiss-Prot
  KV42CHANNEL UniProtKB/Swiss-Prot
  KVCHANNEL UniProtKB/Swiss-Prot
  SHALCHANNEL UniProtKB/Swiss-Prot
SMART BTB UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54695 UniProtKB/Swiss-Prot
  Voltage-gated potassium channels UniProtKB/Swiss-Prot
UniProt KCND2_MOUSE UniProtKB/Swiss-Prot
  Q8BSK3 ENTREZGENE
  Q8CHB7 ENTREZGENE
  Q9JJ60 ENTREZGENE
  Q9Z0V2 ENTREZGENE
UniProt Secondary Q8BSK3 UniProtKB/Swiss-Prot
  Q8CHB7 UniProtKB/Swiss-Prot
  Q9JJ60 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-01-19 Kcnd2  potassium voltage-gated channel, Shal-related family, member 2  Gm52855  predicted gene, 52855  Data merged from RGD:15020559 737654 PROVISIONAL