Symbol:
Slc7a2
Name:
solute carrier family 7 member 2
RGD ID:
68387
Description:
Enables L-arginine transmembrane transporter activity. Involved in L-arginine transmembrane transport. Predicted to be located in cell junction and membrane. Predicted to be active in plasma membrane. Orthologous to human SLC7A2 (solute carrier family 7 member 2); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aciduria type I pathway; hyperlysinemia pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
CAT-2; Cat2; Cat2a; Cat2b; cationic amino acid transporter 2; cationic amino acid transporter-2A; low affinity cationic amino acid transporter 2; RCAT2; solute carrier family 7 (cationic amino acid transporter y+ system) member 2; solute carrier family 7 (cationic amino acid transporter, y+ system), member 2; solute carrier family 7 (cationic amino acid transporter, y+system), member 2; solute carrier family 7, member 2; solute carrier family 7, member 3
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
SLC7A2 (solute carrier family 7 member 2) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):
Slc7a2 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Slc7a2 (solute carrier family 7 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
SLC7A2 (solute carrier family 7 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
SLC7A2 (solute carrier family 7 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Slc7a2 (solute carrier family 7 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
SLC7A2 (solute carrier family 7 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
SLC7A2 (solute carrier family 7 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Slc7a2 (solute carrier family 7 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
SLC7A2 (solute carrier family 7 member 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Slc7a2 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
slc7a2 (solute carrier family 7 member 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
AGP3
Alliance
DIOPT (Ensembl Compara|OrthoInspector)
Drosophila melanogaster (fruit fly):
CG7255
Alliance
DIOPT (Ensembl Compara|Hieranoid|OrthoFinder|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
slif
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
CG5535
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
HNM1
Alliance
DIOPT (Ensembl Compara|InParanoid)
Xenopus tropicalis (tropical clawed frog):
slc7a2.1
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 16 58,115,991 - 58,174,256 (-) NCBI GRCr8 mRatBN7.2 16 51,417,478 - 51,470,784 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 16 51,417,493 - 51,470,784 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 16 56,736,689 - 56,789,896 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 16 60,136,544 - 60,189,834 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 16 55,370,642 - 55,423,851 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 16 54,459,409 - 54,513,349 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 54,460,067 - 54,513,349 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 16 54,171,102 - 54,224,384 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 16 54,752,119 - 54,805,406 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 16 49,310,502 - 49,363,790 (-) NCBI Celera Cytogenetic Map 16 q12.1 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Slc7a2 Rat (1->4)-beta-D-glucan multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SLC7A2 mRNA CTD PMID:36331819 Slc7a2 Rat 17alpha-ethynylestradiol multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC7A2 mRNA CTD PMID:17942748 Slc7a2 Rat 17beta-estradiol multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] results in increased expression of SLC7A2 mRNA CTD PMID:17404688 Slc7a2 Rat 17beta-estradiol decreases expression ISO Slc7a2 (Mus musculus) 6480464 Estradiol results in decreased expression of SLC7A2 mRNA CTD PMID:39298647 Slc7a2 Rat 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of SLC7A2 mRNA CTD PMID:32145629 Slc7a2 Rat 17beta-estradiol increases expression ISO SLC7A2 (Homo sapiens) 6480464 Estradiol results in increased expression of SLC7A2 mRNA CTD PMID:19167446 more ... Slc7a2 Rat 17beta-estradiol decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Estradiol results in decreased expression of SLC7A2 mRNA CTD PMID:21185374 Slc7a2 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin affects the methylation of SLC7A2 intron] which results in decreased expression of SLC7A2 mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC7A2 mRNA CTD PMID:17942748 and PMID:33017471 Slc7a2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Slc7a2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of SLC7A2 mRNA CTD PMID:21570461 more ... Slc7a2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SLC7A2 mRNA CTD PMID:21215274 more ... Slc7a2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SLC7A2 mRNA CTD PMID:22298810 and PMID:32109520 Slc7a2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Slc7a2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of SLC7A2 mRNA CTD PMID:19770486 and PMID:19933214 Slc7a2 Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 Slc7a2 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Slc7a2 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Slc7a2 Rat 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO Slc7a2 (Mus musculus) 6480464 3 more ... CTD PMID:19467301 Slc7a2 Rat 3,3',5,5'-tetrabromobisphenol A decreases expression ISO Slc7a2 (Mus musculus) 6480464 tetrabromobisphenol A results in decreased expression of SLC7A2 mRNA CTD PMID:25172293 Slc7a2 Rat 3-iodothyronamine affects uptake ISO SLC7A2 (Homo sapiens) 6480464 SLC7A2 mRNA affects the uptake of 3-iodothyronamine CTD PMID:19074582 Slc7a2 Rat 4,4'-diaminodiphenylmethane increases expression ISO Slc7a2 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of SLC7A2 mRNA CTD PMID:18648102 Slc7a2 Rat 4,4'-sulfonyldiphenol increases expression ISO Slc7a2 (Mus musculus) 6480464 bisphenol S results in increased expression of SLC7A2 mRNA CTD PMID:30951980 Slc7a2 Rat 4,4'-sulfonyldiphenol decreases expression ISO Slc7a2 (Mus musculus) 6480464 bisphenol S results in decreased expression of SLC7A2 mRNA CTD PMID:39298647 Slc7a2 Rat 4-hydroxynon-2-enal decreases expression ISO Slc7a2 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in decreased expression of SLC7A2 mRNA CTD PMID:19191707 Slc7a2 Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of SLC7A2 mRNA CTD PMID:31881176 Slc7a2 Rat acrolein multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of SLC7A2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of SLC7A2 mRNA CTD PMID:32699268 Slc7a2 Rat aflatoxin B1 decreases expression ISO Slc7a2 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of SLC7A2 mRNA CTD PMID:19770486 Slc7a2 Rat aflatoxin B1 decreases methylation ISO SLC7A2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of SLC7A2 gene CTD PMID:27153756 Slc7a2 Rat aflatoxin B1 decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of SLC7A2 mRNA CTD PMID:27153756 Slc7a2 Rat aldrin decreases expression ISO Slc7a2 (Mus musculus) 6480464 Aldrin results in decreased expression of SLC7A2 mRNA CTD PMID:18579281 Slc7a2 Rat all-trans-retinoic acid increases expression ISO SLC7A2 (Homo sapiens) 6480464 Tretinoin results in increased expression of SLC7A2 mRNA CTD PMID:21934132 Slc7a2 Rat all-trans-retinoic acid decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Tretinoin results in decreased expression of SLC7A2 mRNA CTD PMID:15894607 and PMID:33167477 Slc7a2 Rat alpha-pinene multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of SLC7A2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of SLC7A2 mRNA CTD PMID:32699268 Slc7a2 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SLC7A2 mRNA CTD PMID:16483693 Slc7a2 Rat amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of SLC7A2 mRNA CTD PMID:30779732 Slc7a2 Rat aristolochic acid A decreases expression ISO SLC7A2 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of SLC7A2 mRNA CTD PMID:33212167 Slc7a2 Rat arsane multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of SLC7A2 mRNA CTD PMID:39836092 Slc7a2 Rat arsane multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SLC7A2 mRNA CTD PMID:32045263 Slc7a2 Rat arsenic atom multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of SLC7A2 mRNA CTD PMID:39836092 Slc7a2 Rat arsenic atom multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SLC7A2 mRNA CTD PMID:32045263 Slc7a2 Rat arsenite(3-) decreases expression ISO Slc7a2 (Mus musculus) 6480464 arsenite results in decreased expression of SLC7A2 mRNA CTD PMID:18929588 Slc7a2 Rat arsenite(3-) increases expression ISO Slc7a2 (Mus musculus) 6480464 arsenite results in increased expression of SLC7A2 protein CTD PMID:37955338 Slc7a2 Rat arsenite(3-) multiple interactions ISO Slc7a2 (Mus musculus) 6480464 TRP53 protein affects the reaction [arsenite results in decreased expression of SLC7A2 mRNA] CTD PMID:18929588 Slc7a2 Rat benzo[a]pyrene decreases expression ISO Slc7a2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of SLC7A2 mRNA CTD PMID:19770486 Slc7a2 Rat benzo[a]pyrene increases methylation ISO SLC7A2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of SLC7A2 promoter CTD PMID:27901495 Slc7a2 Rat benzo[a]pyrene affects methylation ISO SLC7A2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of SLC7A2 5' UTR CTD PMID:27901495 Slc7a2 Rat bis(2-ethylhexyl) phthalate increases expression ISO Slc7a2 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of SLC7A2 mRNA CTD PMID:34319233 and PMID:35550907 Slc7a2 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SLC7A2 mRNA CTD PMID:25181051 Slc7a2 Rat bisphenol A decreases expression ISO Slc7a2 (Mus musculus) 6480464 bisphenol A results in decreased expression of SLC7A2 mRNA CTD PMID:32156529 Slc7a2 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SLC7A2 mRNA CTD PMID:32145629 Slc7a2 Rat bisphenol A increases expression ISO SLC7A2 (Homo sapiens) 6480464 bisphenol A analog results in increased expression of SLC7A2 mRNA and bisphenol A results in increased expression of SLC7A2 mRNA CTD PMID:32387340 more ... Slc7a2 Rat bisphenol A increases expression ISO Slc7a2 (Mus musculus) 6480464 bisphenol A results in increased expression of SLC7A2 mRNA CTD PMID:30951980 Slc7a2 Rat bisphenol AF increases expression EXP 6480464 bisphenol AF results in increased expression of SLC7A2 mRNA CTD PMID:27567155 Slc7a2 Rat Bisphenol B increases expression ISO SLC7A2 (Homo sapiens) 6480464 bisphenol B results in increased expression of SLC7A2 mRNA CTD PMID:32387340 Slc7a2 Rat bisphenol F increases expression ISO Slc7a2 (Mus musculus) 6480464 bisphenol F results in increased expression of SLC7A2 mRNA CTD PMID:30951980 and PMID:38685157 Slc7a2 Rat Bisphenol Z increases expression ISO SLC7A2 (Homo sapiens) 6480464 bisphenol Z results in increased expression of SLC7A2 mRNA CTD PMID:32387340 Slc7a2 Rat calcitriol decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Calcitriol results in decreased expression of SLC7A2 mRNA CTD PMID:21592394 Slc7a2 Rat calcitriol multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of SLC7A2 mRNA CTD PMID:21592394 Slc7a2 Rat carbon nanotube increases expression ISO Slc7a2 (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of SLC7A2 mRNA CTD PMID:25554681 Slc7a2 Rat CGP 52608 multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to SLC7A2 gene] CTD PMID:28238834 Slc7a2 Rat choline multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SLC7A2 mRNA CTD PMID:20938992 Slc7a2 Rat ciguatoxin CTX1B affects expression ISO Slc7a2 (Mus musculus) 6480464 Ciguatoxins affects the expression of SLC7A2 mRNA CTD PMID:18353800 Slc7a2 Rat cisplatin decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Cisplatin results in decreased expression of SLC7A2 mRNA CTD PMID:27594783 Slc7a2 Rat clofibrate multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SLC7A2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SLC7A2 mRNA] CTD PMID:17585979 Slc7a2 Rat clofibrate decreases expression ISO Slc7a2 (Mus musculus) 6480464 Clofibrate results in decreased expression of SLC7A2 mRNA CTD PMID:17585979 Slc7a2 Rat clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SLC7A2 mRNA CTD PMID:17602206 Slc7a2 Rat copper atom multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in decreased expression of SLC7A2 mRNA CTD PMID:20971185 Slc7a2 Rat copper(0) multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in decreased expression of SLC7A2 mRNA CTD PMID:20971185 Slc7a2 Rat copper(II) chloride increases expression ISO SLC7A2 (Homo sapiens) 6480464 cupric chloride results in increased expression of SLC7A2 mRNA CTD PMID:38568856 Slc7a2 Rat copper(II) sulfate decreases expression ISO Slc7a2 (Mus musculus) 6480464 Copper Sulfate results in decreased expression of SLC7A2 mRNA CTD PMID:18579281 Slc7a2 Rat crocidolite asbestos affects expression ISO SLC7A2 (Homo sapiens) 6480464 Asbestos and Crocidolite affects the expression of SLC7A2 mRNA CTD PMID:24160326 and PMID:25757056 Slc7a2 Rat cyclosporin A increases expression ISO SLC7A2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of SLC7A2 mRNA CTD PMID:20106945 and PMID:27989131 Slc7a2 Rat cyclosporin A affects expression ISO SLC7A2 (Homo sapiens) 6480464 Cyclosporine affects the expression of SLC7A2 mRNA CTD PMID:25562108 Slc7a2 Rat cyclosporin A decreases expression ISO Slc7a2 (Mus musculus) 6480464 Cyclosporine results in decreased expression of SLC7A2 mRNA CTD PMID:19770486 Slc7a2 Rat cytarabine decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Cytarabine results in decreased expression of SLC7A2 mRNA CTD PMID:21198554 Slc7a2 Rat diallyl trisulfide increases expression ISO SLC7A2 (Homo sapiens) 6480464 diallyl trisulfide results in increased expression of SLC7A2 mRNA CTD PMID:34995734 Slc7a2 Rat dieldrin decreases expression EXP 6480464 Dieldrin results in decreased expression of SLC7A2 mRNA CTD PMID:23153324 Slc7a2 Rat dorsomorphin multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Slc7a2 Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of SLC7A2 mRNA CTD PMID:29391264 Slc7a2 Rat epoxiconazole decreases expression ISO Slc7a2 (Mus musculus) 6480464 epoxiconazole results in decreased expression of SLC7A2 mRNA CTD PMID:35436446 Slc7a2 Rat ethanol increases expression ISO Slc7a2 (Mus musculus) 6480464 Ethanol results in increased expression of SLC7A2 mRNA CTD PMID:30319688 Slc7a2 Rat flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of SLC7A2 mRNA CTD PMID:18035473 Slc7a2 Rat folic acid multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SLC7A2 mRNA CTD PMID:20938992 Slc7a2 Rat furan increases methylation EXP 6480464 furan results in increased methylation of SLC7A2 gene CTD PMID:22079235 Slc7a2 Rat gamma-hexachlorocyclohexane increases expression EXP 6480464 Hexachlorocyclohexane results in increased expression of SLC7A2 mRNA CTD PMID:17785943 Slc7a2 Rat genistein increases expression ISO Slc7a2 (Mus musculus) 6480464 Genistein results in increased expression of SLC7A2 mRNA CTD PMID:32186404 Slc7a2 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of SLC7A2 mRNA CTD PMID:33387578 Slc7a2 Rat heptachlor decreases expression EXP 6480464 Heptachlor results in decreased expression of SLC7A2 mRNA CTD PMID:23153324 Slc7a2 Rat inulin multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SLC7A2 mRNA CTD PMID:36331819 Slc7a2 Rat L-methionine multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SLC7A2 mRNA CTD PMID:20938992 Slc7a2 Rat leflunomide increases expression ISO SLC7A2 (Homo sapiens) 6480464 leflunomide results in increased expression of SLC7A2 mRNA CTD PMID:28988120 Slc7a2 Rat lipopolysaccharide increases expression ISO Slc7a2 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of SLC7A2 mRNA CTD PMID:23415871 Slc7a2 Rat lipopolysaccharide increases expression ISO SLC7A2 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of SLC7A2 mRNA CTD PMID:35811015 Slc7a2 Rat lipopolysaccharide multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of SLC7A2 mRNA] CTD PMID:35811015 Slc7a2 Rat manganese atom multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of SLC7A2 mRNA CTD PMID:39836092 Slc7a2 Rat manganese(0) multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of SLC7A2 mRNA CTD PMID:39836092 Slc7a2 Rat manganese(II) chloride multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of SLC7A2 mRNA CTD PMID:39836092 Slc7a2 Rat medroxyprogesterone acetate increases expression ISO SLC7A2 (Homo sapiens) 6480464 Medroxyprogesterone Acetate results in increased expression of SLC7A2 mRNA CTD PMID:20843944 Slc7a2 Rat mercury atom decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Mercury results in decreased expression of SLC7A2 mRNA CTD PMID:19937285 Slc7a2 Rat mercury dibromide increases expression ISO SLC7A2 (Homo sapiens) 6480464 mercuric bromide results in increased expression of SLC7A2 mRNA CTD PMID:26272509 Slc7a2 Rat mercury dibromide multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A2 mRNA CTD PMID:27188386 Slc7a2 Rat mercury(0) decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Mercury results in decreased expression of SLC7A2 mRNA CTD PMID:19937285 Slc7a2 Rat methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of SLC7A2 mRNA CTD PMID:30467583 Slc7a2 Rat methylmercury chloride decreases expression ISO SLC7A2 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of SLC7A2 mRNA CTD PMID:23179753 Slc7a2 Rat mirex decreases expression EXP 6480464 Mirex results in decreased expression of SLC7A2 mRNA CTD PMID:23153324 Slc7a2 Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SLC7A2 mRNA CTD PMID:17602206 Slc7a2 Rat nickel dichloride increases expression ISO SLC7A2 (Homo sapiens) 6480464 nickel chloride results in increased expression of SLC7A2 mRNA CTD PMID:17312168 Slc7a2 Rat ozone multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of SLC7A2 mRNA more ... CTD PMID:32699268 Slc7a2 Rat paracetamol multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SLC7A2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SLC7A2 mRNA] CTD PMID:17585979 Slc7a2 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of SLC7A2 mRNA CTD PMID:33387578 Slc7a2 Rat paracetamol affects expression ISO SLC7A2 (Homo sapiens) 6480464 Acetaminophen affects the expression of SLC7A2 mRNA CTD PMID:21420995 Slc7a2 Rat parathion increases expression ISO Slc7a2 (Mus musculus) 6480464 Parathion results in increased expression of SLC7A2 mRNA CTD PMID:34813904 Slc7a2 Rat perfluorohexanesulfonic acid decreases expression ISO Slc7a2 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in decreased expression of SLC7A2 mRNA CTD PMID:37995155 Slc7a2 Rat perfluorononanoic acid increases expression ISO SLC7A2 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in increased expression of SLC7A2 mRNA CTD PMID:32588087 Slc7a2 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SLC7A2 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SLC7A2 mRNA CTD PMID:36331819 Slc7a2 Rat phenobarbital multiple interactions ISO Slc7a2 (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SLC7A2 mRNA] CTD PMID:19482888 Slc7a2 Rat phenobarbital decreases expression ISO Slc7a2 (Mus musculus) 6480464 Phenobarbital results in decreased expression of SLC7A2 mRNA CTD PMID:19482888 and PMID:23091169 Slc7a2 Rat phenobarbital increases expression ISO Slc7a2 (Mus musculus) 6480464 Phenobarbital results in increased expression of SLC7A2 mRNA CTD PMID:19270015 Slc7a2 Rat phenylmercury acetate increases expression ISO SLC7A2 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of SLC7A2 mRNA CTD PMID:26272509 Slc7a2 Rat phenylmercury acetate multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A2 mRNA CTD PMID:27188386 Slc7a2 Rat picene decreases expression ISO SLC7A2 (Homo sapiens) 6480464 picene results in decreased expression of SLC7A2 mRNA CTD PMID:32251684 Slc7a2 Rat pirinixic acid multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC7A2 mRNA CTD PMID:19710929 Slc7a2 Rat pirinixic acid increases expression ISO Slc7a2 (Mus musculus) 6480464 pirinixic acid results in increased expression of SLC7A2 mRNA CTD PMID:18445702 Slc7a2 Rat progesterone multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] results in increased expression of SLC7A2 mRNA CTD PMID:17404688 Slc7a2 Rat propiconazole decreases expression ISO Slc7a2 (Mus musculus) 6480464 propiconazole results in decreased expression of SLC7A2 mRNA CTD PMID:21278054 Slc7a2 Rat resveratrol multiple interactions ISO Slc7a2 (Mus musculus) 6480464 Resveratrol inhibits the reaction [titanium dioxide results in decreased expression of SLC7A2 mRNA] CTD PMID:31298478 Slc7a2 Rat rotenone increases expression EXP 6480464 Rotenone results in increased expression of SLC7A2 mRNA CTD PMID:28374803 Slc7a2 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of SLC7A2 mRNA] CTD PMID:35811015 Slc7a2 Rat SB 431542 multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Slc7a2 Rat serpentine asbestos affects expression ISO SLC7A2 (Homo sapiens) 6480464 Asbestos and Serpentine affects the expression of SLC7A2 mRNA CTD PMID:24160326 Slc7a2 Rat sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of SLC7A2 mRNA CTD PMID:15967596 Slc7a2 Rat silver atom decreases expression ISO Slc7a2 (Mus musculus) 6480464 Silver results in decreased expression of SLC7A2 mRNA CTD PMID:27131904 Slc7a2 Rat silver(0) decreases expression ISO Slc7a2 (Mus musculus) 6480464 Silver results in decreased expression of SLC7A2 mRNA CTD PMID:27131904 Slc7a2 Rat sodium arsenite increases expression ISO SLC7A2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of SLC7A2 mRNA CTD PMID:38568856 Slc7a2 Rat sodium arsenite multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of SLC7A2 mRNA CTD PMID:39836092 Slc7a2 Rat sodium arsenite multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SLC7A2 mRNA CTD PMID:32045263 Slc7a2 Rat sunitinib increases expression ISO SLC7A2 (Homo sapiens) 6480464 Sunitinib results in increased expression of SLC7A2 mRNA CTD PMID:31533062 Slc7a2 Rat T-2 toxin decreases expression ISO SLC7A2 (Homo sapiens) 6480464 T-2 Toxin results in decreased expression of SLC7A2 mRNA CTD PMID:31863870 Slc7a2 Rat testosterone multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of SLC7A2 mRNA CTD PMID:21592394 Slc7a2 Rat testosterone decreases expression ISO Slc7a2 (Mus musculus) 6480464 Testosterone results in decreased expression of SLC7A2 mRNA CTD PMID:20403060 and PMID:21669218 Slc7a2 Rat testosterone decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Testosterone results in decreased expression of SLC7A2 mRNA CTD PMID:21592394 Slc7a2 Rat tetrachloromethane decreases expression ISO Slc7a2 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of SLC7A2 mRNA CTD PMID:31919559 Slc7a2 Rat titanium dioxide decreases expression ISO Slc7a2 (Mus musculus) 6480464 titanium dioxide results in decreased expression of SLC7A2 mRNA CTD PMID:31298478 Slc7a2 Rat titanium dioxide increases methylation ISO Slc7a2 (Mus musculus) 6480464 titanium dioxide results in increased methylation of SLC7A2 promoter CTD PMID:35295148 Slc7a2 Rat titanium dioxide multiple interactions ISO Slc7a2 (Mus musculus) 6480464 Resveratrol inhibits the reaction [titanium dioxide results in decreased expression of SLC7A2 mRNA] CTD PMID:31298478 Slc7a2 Rat trichostatin A increases expression ISO SLC7A2 (Homo sapiens) 6480464 trichostatin A results in increased expression of SLC7A2 mRNA CTD PMID:24935251 and PMID:26272509 Slc7a2 Rat trichostatin A multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A2 mRNA CTD PMID:27188386 Slc7a2 Rat Triptolide decreases expression ISO Slc7a2 (Mus musculus) 6480464 triptolide results in decreased expression of SLC7A2 mRNA CTD PMID:32835833 Slc7a2 Rat troglitazone decreases expression ISO Slc7a2 (Mus musculus) 6480464 troglitazone results in decreased expression of SLC7A2 mRNA CTD PMID:28973697 Slc7a2 Rat trovafloxacin multiple interactions ISO Slc7a2 (Mus musculus) 6480464 [trovafloxacin co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of SLC7A2 mRNA CTD PMID:18930950 Slc7a2 Rat valproic acid affects expression ISO Slc7a2 (Mus musculus) 6480464 Valproic Acid affects the expression of SLC7A2 mRNA CTD PMID:17963808 Slc7a2 Rat valproic acid multiple interactions ISO SLC7A2 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC7A2 mRNA CTD PMID:27188386 Slc7a2 Rat valproic acid increases expression ISO SLC7A2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of SLC7A2 mRNA CTD PMID:23179753 more ... Slc7a2 Rat valproic acid decreases methylation ISO SLC7A2 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of SLC7A2 gene CTD PMID:29154799 Slc7a2 Rat zearalenone increases expression ISO SLC7A2 (Homo sapiens) 6480464 Zearalenone results in increased expression of SLC7A2 mRNA CTD PMID:36828454 Slc7a2 Rat zidovudine decreases expression ISO SLC7A2 (Homo sapiens) 6480464 Zidovudine results in decreased expression of SLC7A2 mRNA CTD PMID:24292225 Slc7a2 Rat zoledronic acid decreases expression ISO SLC7A2 (Homo sapiens) 6480464 zoledronic acid results in decreased expression of SLC7A2 mRNA CTD PMID:24714768
Imported Annotations - SMPDB
(1->4)-beta-D-glucan (ISO) 17alpha-ethynylestradiol (ISO) 17beta-estradiol (EXP,ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,3,7,8-Tetrachlorodibenzofuran (EXP) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 3,3',4,4'-tetrachlorobiphenyl (ISO) 3,3',5,5'-tetrabromobisphenol A (ISO) 3-iodothyronamine (ISO) 4,4'-diaminodiphenylmethane (ISO) 4,4'-sulfonyldiphenol (ISO) 4-hydroxynon-2-enal (ISO) acetamide (EXP) acrolein (ISO) aflatoxin B1 (ISO) aldrin (ISO) all-trans-retinoic acid (ISO) alpha-pinene (ISO) ammonium chloride (EXP) amphetamine (EXP) aristolochic acid A (ISO) arsane (ISO) arsenic atom (ISO) arsenite(3-) (ISO) benzo[a]pyrene (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol AF (EXP) Bisphenol B (ISO) bisphenol F (ISO) Bisphenol Z (ISO) calcitriol (ISO) carbon nanotube (ISO) CGP 52608 (ISO) choline (ISO) ciguatoxin CTX1B (ISO) cisplatin (ISO) clofibrate (ISO) clofibric acid (EXP) copper atom (ISO) copper(0) (ISO) copper(II) chloride (ISO) copper(II) sulfate (ISO) crocidolite asbestos (ISO) cyclosporin A (ISO) cytarabine (ISO) diallyl trisulfide (ISO) dieldrin (EXP) dorsomorphin (ISO) endosulfan (EXP) epoxiconazole (ISO) ethanol (ISO) flavonoids (EXP) folic acid (ISO) furan (EXP) gamma-hexachlorocyclohexane (EXP) genistein (ISO) gentamycin (EXP) heptachlor (EXP) inulin (ISO) L-methionine (ISO) leflunomide (ISO) lipopolysaccharide (ISO) manganese atom (ISO) manganese(0) (ISO) manganese(II) chloride (ISO) medroxyprogesterone acetate (ISO) mercury atom (ISO) mercury dibromide (ISO) mercury(0) (ISO) methapyrilene (EXP) methylmercury chloride (ISO) mirex (EXP) N-nitrosodiethylamine (EXP) nickel dichloride (ISO) ozone (ISO) paracetamol (EXP,ISO) parathion (ISO) perfluorohexanesulfonic acid (ISO) perfluorononanoic acid (ISO) perfluorooctane-1-sulfonic acid (ISO) phenobarbital (ISO) phenylmercury acetate (ISO) picene (ISO) pirinixic acid (ISO) progesterone (ISO) propiconazole (ISO) resveratrol (ISO) rotenone (EXP) S-(1,2-dichlorovinyl)-L-cysteine (ISO) SB 431542 (ISO) serpentine asbestos (ISO) sevoflurane (EXP) silver atom (ISO) silver(0) (ISO) sodium arsenite (ISO) sunitinib (ISO) T-2 toxin (ISO) testosterone (ISO) tetrachloromethane (ISO) titanium dioxide (ISO) trichostatin A (ISO) Triptolide (ISO) troglitazone (ISO) trovafloxacin (ISO) valproic acid (ISO) zearalenone (ISO) zidovudine (ISO) zoledronic acid (ISO)
1.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.
Interleukin-1 beta and tumor necrosis factor-alpha stimulate the cat-2 gene of the L-arginine transporter in cultured vascular smooth muscle cells.
Gill DJ, etal., J Biol Chem. 1996 May 10;271(19):11280-3.
3.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
4.
Nuclear factor-kappaB mediates simultaneous induction of inducible nitric-oxide synthase and Up-regulation of the cationic amino acid transporter CAT-2B in rat alveolar macrophages.
Hammermann R, etal., Mol Pharmacol 2000 Dec;58(6):1294-302.
5.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
6.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.
SMPDB Annotation Import Pipeline
Pipeline to import SMPDB annotations from SMPDB into RGD
8.
GOA pipeline
RGD automated data pipeline
9.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
11.
Differential regulation of glomerular arginine transporters (CAT-1 and CAT-2) in lipopolysaccharide-treated rats.
Schwartz D, etal., Am J Physiol Renal Physiol 2003 Apr;284(4):F788-95.
12.
Tetrahydrobiopterin augments arginine transport in rat cardiac myocytes through modulation of CAT-2 mRNA.
Schwartz IF, etal., J Lab Clin Med. 2001 May;137(5):356-62.
13.
L-Arginine transport is augmented through up-regulation of tubular CAT-2 mRNA in ischemic acute renal failure in rats.
Schwartz IF, etal., Kidney Int 2002 Nov;62(5):1700-6.
14.
Differential regulation of L-arginine transporters (cationic amino acid transporter-1 and -2) by peroxynitrite in rat mesangial cells.
Schwartz IF, etal., Nephrol Dial Transplant. 2006 Dec;21(12):3409-14. Epub 2006 Sep 23.
15.
Induced nitric oxide synthesis is dependent on induced alternatively spliced CAT-2 encoding L-arginine transport in brain astrocytes.
Stevens BR, etal., J Biol Chem 1996 Sep 27;271(39):24017-22.
Slc7a2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 16 58,115,991 - 58,174,256 (-) NCBI GRCr8 mRatBN7.2 16 51,417,478 - 51,470,784 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 16 51,417,493 - 51,470,784 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 16 56,736,689 - 56,789,896 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 16 60,136,544 - 60,189,834 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 16 55,370,642 - 55,423,851 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 16 54,459,409 - 54,513,349 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 54,460,067 - 54,513,349 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 16 54,171,102 - 54,224,384 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 16 54,752,119 - 54,805,406 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 16 49,310,502 - 49,363,790 (-) NCBI Celera Cytogenetic Map 16 q12.1 NCBI
SLC7A2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 8 17,494,069 - 17,570,566 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 8 17,497,088 - 17,570,573 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 8 17,354,597 - 17,428,075 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 8 17,440,665 - 17,472,352 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 8 17,440,684 - 17,472,296 NCBI Celera 8 16,320,372 - 16,393,730 (+) NCBI Celera Cytogenetic Map 8 p22 NCBI HuRef 8 15,899,173 - 15,972,649 (+) NCBI HuRef CHM1_1 8 17,556,088 - 17,629,545 (+) NCBI CHM1_1 T2T-CHM13v2.0 8 17,761,599 - 17,837,697 (+) NCBI T2T-CHM13v2.0
Slc7a2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 8 41,315,404 - 41,375,107 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 8 41,315,433 - 41,375,345 (+) Ensembl GRCm39 Ensembl GRCm38 8 40,862,341 - 40,922,070 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 8 40,862,396 - 40,922,308 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 8 41,947,721 - 42,007,424 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 8 42,361,229 - 42,421,125 (+) NCBI MGSCv36 mm8 Celera 8 43,496,255 - 43,555,499 (+) NCBI Celera Cytogenetic Map 8 A4 NCBI cM Map 8 23.89 NCBI
Slc7a2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955552 2,117,755 - 2,141,231 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955552 2,117,972 - 2,141,144 (-) NCBI ChiLan1.0 ChiLan1.0
SLC7A2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 7 35,969,973 - 36,043,781 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 8 11,704,679 - 11,770,243 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 8 16,723,227 - 16,788,745 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 8 13,671,571 - 13,741,007 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 8 13,671,571 - 13,735,645 (+) Ensembl panpan1.1 panPan2
SLC7A2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 16 40,855,270 - 40,879,956 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 16 40,745,458 - 40,875,106 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 16 41,312,676 - 41,387,063 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 16 42,867,670 - 42,935,808 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 16 42,867,675 - 42,935,804 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 16 40,961,049 - 41,029,086 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 16 41,504,575 - 41,572,831 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 16 41,699,102 - 41,767,417 (+) NCBI UU_Cfam_GSD_1.0
Slc7a2
SLC7A2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 17 5,192,022 - 5,271,849 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 17 5,191,973 - 5,271,849 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 17 5,704,846 - 5,725,732 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
SLC7A2 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 8 15,591,795 - 15,665,837 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 8 15,638,113 - 15,660,487 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666052 26,611,997 - 26,686,779 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Slc7a2
.
Predicted Target Of
Count of predictions: 497 Count of miRNA genes: 165 Interacting mature miRNAs: 190 Transcripts: ENSRNOT00000014809, ENSRNOT00000015127, ENSRNOT00000059032 Prediction methods: Microtar, Miranda, Rnahybrid Result types: miRGate_prediction
2300163 Bmd64 Bone mineral density QTL 64 5.3 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 16 37752156 82752156 Rat 1600378 Arunc4 Aerobic running capacity QTL 4 0.03 exercise endurance trait (VT:0002332) maximum distance run on treadmill (CMO:0001406) 16 380245 80345693 Rat 70215 Niddm29 Non-insulin dependent diabetes mellitus QTL 29 3.54 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 16 19004435 75226532 Rat 1578768 Stresp22 Stress response QTL 22 2.8 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 16 35288870 80288870 Rat 737826 Alc11 Alcohol consumption QTL 11 3.2 consumption behavior trait (VT:0002069) ethanol drink intake rate (CMO:0001407) 16 4227609 60252231 Rat 2302057 Pia29 Pristane induced arthritis QTL 29 3.6 0.001 blood autoantibody amount (VT:0003725) serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111) 16 21735975 66735975 Rat 7205510 Activ5 Activity QTL 5 3.78 0.00028 locomotor behavior trait (VT:0001392) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 16 42396345 84729064 Rat 8694453 Bw172 Body weight QTL 172 8.33 0.001 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 16 24325513 69325513 Rat 1298529 Arunc1 Aerobic running capacity QTL 1 4 exercise endurance trait (VT:0002332) maximum distance run on treadmill (CMO:0001406) 16 31951520 60148445 Rat 2312663 Slep9 Serum leptin concentration QTL 9 0.001 blood leptin amount (VT:0005667) serum leptin level (CMO:0000780) 16 832236 59492508 Rat 2312660 Bw95 Body weight QTL 95 0.05 inguinal fat pad mass (VT:0010424) inguinal fat pad weight to body weight ratio (CMO:0001253) 16 832236 59492508 Rat 6903294 Stl30 Serum triglyceride level QTL 30 2.6 0.0013 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 16 25152793 70152793 Rat 2293690 Bss45 Bone structure and strength QTL 45 5.13 0.0001 lumbar vertebra morphology trait (VT:0010494) lumbar vertebra cortical cross-sectional area (CMO:0001690) 16 37752156 82752156 Rat 2312666 Insul16 Insulin level QTL 16 0.01 blood insulin amount (VT:0001560) serum insulin level (CMO:0000358) 16 832236 59492508 Rat 70205 Gcr3 Gastric cancer resistance QTL 3 2.3 stomach morphology trait (VT:0000470) stomach tumor diameter (CMO:0001889) 16 17696791 82635055 Rat 2312669 Stl23 Serum triglyceride level QTL 23 0.01 blood triglyceride amount (VT:0002644) serum triglyceride level (CMO:0000360) 16 832236 59492508 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
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Ensembl Acc Id:
ENSRNOT00000014809 ⟹ ENSRNOP00000014809
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 16 51,417,493 - 51,470,784 (-) Ensembl Rnor_6.0 Ensembl 16 54,460,067 - 54,513,349 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000015127 ⟹ ENSRNOP00000015127
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 16 51,417,493 - 51,470,784 (-) Ensembl Rnor_6.0 Ensembl 16 54,460,067 - 54,513,349 (-) Ensembl
RefSeq Acc Id:
NM_001134686 ⟹ NP_001128158
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 16 58,120,968 - 58,174,256 (-) NCBI mRatBN7.2 16 51,417,493 - 51,470,784 (-) NCBI Rnor_6.0 16 54,460,067 - 54,513,349 (-) NCBI Rnor_5.0 16 54,171,102 - 54,224,384 (-) NCBI RGSC_v3.4 16 54,752,119 - 54,805,406 (-) RGD Celera 16 49,310,502 - 49,363,790 (-) RGD
Sequence:
GTGCCCAGCCCGCCTTCTGCAGCTCGGCGGCGGGAGCTTCTGTCTGCGCGGACCTGGAAGACGGCGGCAGCTCGTCTAGCCTTCGAGAGCTTGGGAACCGCAGAGCGCTGCAGCCGGTCGTCCGCTGG
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RefSeq Acc Id:
NM_022619 ⟹ NP_072141
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 16 58,120,968 - 58,174,256 (-) NCBI mRatBN7.2 16 51,417,493 - 51,470,784 (-) NCBI Rnor_6.0 16 54,460,067 - 54,513,349 (-) NCBI Rnor_5.0 16 54,171,102 - 54,224,384 (-) NCBI RGSC_v3.4 16 54,752,119 - 54,805,406 (-) RGD Celera 16 49,310,502 - 49,363,790 (-) RGD
Sequence:
GTGCCCAGCCCGCCTTCTGCAGCTCGGCGGCGGGAGCTTCTGTCTGCGCGGACCTGGAAGACGGCGGCAGCTCGTCTAGCCTTCGAGAGCTTGGGAACCGCAGAGCGCTGCAGCCGGTCGTCCGCTGG
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RefSeq Acc Id:
XM_039094810 ⟹ XP_038950738
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 16 58,115,991 - 58,174,047 (-) NCBI mRatBN7.2 16 51,417,478 - 51,470,566 (-) NCBI
RefSeq Acc Id:
NP_072141 ⟸ NM_022619
- Peptide Label:
isoform a
- UniProtKB:
B5D5P0 (UniProtKB/Swiss-Prot), B5D5N9 (UniProtKB/Swiss-Prot), Q925V9 (UniProtKB/TrEMBL)
- Sequence:
MIPCRAVLTFTRCLIRRKIVTLDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTS
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RefSeq Acc Id:
NP_001128158 ⟸ NM_001134686
- Peptide Label:
isoform b
- UniProtKB:
Q925V9 (UniProtKB/TrEMBL)
- Sequence:
MIPCRAVLTFTRCLIRRKIVTLDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADS
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Ensembl Acc Id:
ENSRNOP00000014809 ⟸ ENSRNOT00000014809
Ensembl Acc Id:
ENSRNOP00000015127 ⟸ ENSRNOT00000015127
RefSeq Acc Id:
XP_038950738 ⟸ XM_039094810
- Peptide Label:
isoform X1
- UniProtKB:
Q925V9 (UniProtKB/TrEMBL)
RGD ID: 13700121 Promoter ID: EPDNEW_R10645 Type: initiation region Name: Slc7a2_1 Description: solute carrier family 7 member 2 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 16 54,513,338 - 54,513,398 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-03-09
Slc7a2
solute carrier family 7 member 2
Slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2004-09-10
Slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
solute carrier family 7, member 3
Name updated
1299863 APPROVED
2002-06-10
Slc7a2
solute carrier family 7, member 3
Name updated
70584 APPROVED
Note Type
Note
Reference
gene_regulation
mRNA expression is upregulated by ischemic acute renal failure leading to increased NO production and increase L-arginine transport
