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Gene: Vapb (VAMP associated protein B and C) Rattus norvegicus

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Symbol:

Vapb

Name:

VAMP associated protein B and C

RGD ID:

68326

Description:

Predicted to enable several functions, including FFAT motif binding activity; protein dimerization activity; and tubulin binding activity. Predicted to be involved in several processes, including IRE1-mediated unfolded protein response; endoplasmic reticulum organization; and host-mediated activation of viral genome replication. Is active in several cellular components, including glutamatergic synapse; postsynapse; and presynapse. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 8; autosomal dominant adult-onset proximal spinal muscular atrophy; and spinal muscular atrophy. Orthologous to human VAPB (VAMP associated protein B and C); INTERACTS WITH 17beta-estradiol; 4-phenylbutyric acid; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

MGC72459; VAMP (vesicle-associated membrane protein)-associated protein B and C; VAMP-associated protein B; VAMP-B; VAP-B; vesicle-associated membrane protein, associated protein B and C; vesicle-associated membrane protein-associated protein B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	VAPB (VAMP associated protein B and C)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Vapb (vesicle-associated membrane protein, associated protein B and C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Vapb (VAMP associated protein B and C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	VAPB (VAMP associated protein B and C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	VAPB (VAMP associated protein B and C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Vapb (VAMP associated protein B and C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	VAPB (VAMP associated protein B and C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	VAPB (VAMP associated protein B and C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Vapb (VAMP associated protein B and C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Vapb (VAMP associated protein B and C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	VAPB (VAMP associated protein B and C)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Vapb (vesicle-associated membrane protein, associated protein B and C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	vapb (VAMP (vesicle-associated membrane protein)-associated protein B and C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F42G2.5	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SCS2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SCS2	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SCS22	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Vap33	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Vap33	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	fan	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	ZC196.2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	vpr-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	vapb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	vapb	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)

Candidate Gene For:

Eau4

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	182,954,247 - 182,997,018 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	182,954,240 - 183,028,619 (+)	Ensembl				GRCr8
mRatBN7.2	3	162,535,974 - 162,578,747 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	162,535,905 - 162,573,763 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	166,335,144 - 166,371,611 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	174,838,730 - 174,875,679 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	172,575,947 - 172,612,410 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	171,832,558 - 171,871,042 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	171,832,500 - 171,868,647 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	177,890,856 - 177,931,543 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	164,632,388 - 164,669,187 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	161,718,437 - 161,754,637 (+)	NCBI		Celera
RGSC_v3.1	3	164,538,238 - 164,576,441 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amyotrophic lateral sclerosis (ISO)

amyotrophic lateral sclerosis type 1 (ISO)

amyotrophic lateral sclerosis type 8 (ISO)

autosomal dominant adult-onset proximal spinal muscular atrophy (ISO)

genetic disease (ISO)

spinal muscular atrophy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dimethoxyphenol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-phenylbutyric acid (EXP)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (ISO)

aconitine (EXP)

ammonium chloride (EXP)

antimycin A (ISO)

antirheumatic drug (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Brodifacoum (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

celecoxib (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

clozapine (ISO)

cocaine (EXP)

coumarin (ISO)

Cuprizon (ISO)

deguelin (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenpyroximate (ISO)

finasteride (EXP)

flufenoxuron (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

furfural (ISO)

geldanamycin (ISO)

hydrogen cyanide (ISO)

ivermectin (ISO)

lanthanum trichloride (EXP)

lead(0) (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

ozone (EXP,ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

pentachlorophenol (ISO)

picoxystrobin (ISO)

potassium cyanide (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

pyrimidifen (ISO)

quercetin (ISO)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sulindac (EXP)

tebufenpyrad (ISO)

thapsigargin (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cholesterol transport (IEA,ISO)

COPII-coated vesicle budding (IEA,ISO)

endoplasmic reticulum membrane organization (IBA)

endoplasmic reticulum organization (IEA,ISO)

endoplasmic reticulum to Golgi vesicle-mediated transport (IEA,ISO)

endoplasmic reticulum unfolded protein response (IEA,ISO,ISS)

endoplasmic reticulum-plasma membrane tethering (IBA)

host-mediated activation of viral genome replication (ISO)

host-mediated perturbation of viral RNA genome replication (ISO)

host-mediated suppression of viral genome replication (ISO)

intracellular calcium ion homeostasis (IEA,ISO,ISS)

IRE1-mediated unfolded protein response (IEA,ISO,ISS)

negative regulation by virus of viral protein levels in host cell (ISO)

positive regulation of viral genome replication (IEA,ISO,ISS)

response to unfolded protein (IEA)

suppression of viral release by host (ISO)

viral release from host cell (ISO)

Cellular Component

cytoplasm (IEA,ISO)

endoplasmic reticulum (IDA,IEA,IEP,ISO,ISS)

endoplasmic reticulum exit site (ISO)

endoplasmic reticulum membrane (IBA,IEA,ISO,ISS)

glutamatergic synapse (IDA,IEP)

Golgi apparatus (IEA,ISO,ISS)

membrane (ISO)

plasma membrane (IBA)

postsynapse (IDA,IEP)

presynapse (IDA,IEP)

Molecular Function

beta-tubulin binding (IEA,ISO,ISS)

enzyme binding (IEA,ISO,ISS)

FFAT motif binding (IEA,ISO)

microtubule binding (IEA,ISO)

protein binding (ISO)

protein heterodimerization activity (IEA,ISO)

protein homodimerization activity (IEA,ISO,ISS)

protein-membrane adaptor activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity.	Gómez-Suaga P, etal., Acta Neuropathol Commun. 2019 Mar 6;7(1):35. doi: 10.1186/s40478-019-0688-4.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis.	Nishimura AL, etal., Am J Hum Genet. 2004 Nov;75(5):822-31. Epub 2004 Sep 15.
6.	Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins.	Nishimura Y, etal., Biochem Biophys Res Commun 1999 Jan 8;254(1):21-6.
7.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:14561759	PMID:15489334	PMID:16227268	PMID:16891305	PMID:17540579	PMID:18713837	PMID:19515777	PMID:20940299	PMID:21275991	PMID:22131369	PMID:23736259
PMID:24105263	PMID:25468996	PMID:29941597

Genomics

Comparative Map Data

Vapb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	182,954,247 - 182,997,018 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	182,954,240 - 183,028,619 (+)	Ensembl				GRCr8
mRatBN7.2	3	162,535,974 - 162,578,747 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	162,535,905 - 162,573,763 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	166,335,144 - 166,371,611 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	174,838,730 - 174,875,679 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	172,575,947 - 172,612,410 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	171,832,558 - 171,871,042 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	171,832,500 - 171,868,647 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	177,890,856 - 177,931,543 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	164,632,388 - 164,669,187 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	161,718,437 - 161,754,637 (+)	NCBI		Celera
RGSC_v3.1	3	164,538,238 - 164,576,441 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

VAPB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	58,389,229 - 58,451,101 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	58,389,119 - 58,451,101 (+)	Ensembl			hg38	GRCh38
GRCh37	20	56,964,285 - 57,026,157 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	56,397,651 - 56,455,369 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	56,397,650 - 56,455,367	NCBI
Celera	20	53,704,711 - 53,762,426 (+)	NCBI		Celera
Cytogenetic Map	20	q13.32	NCBI
HuRef	20	53,747,058 - 53,809,032 (+)	NCBI		HuRef
CHM1_1	20	56,865,734 - 56,927,715 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	60,170,197 - 60,232,150 (+)	NCBI		T2T-CHM13v2.0

Vapb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	173,579,378 - 173,626,132 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	173,579,304 - 173,626,132 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	173,737,571 - 173,784,336 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	173,737,511 - 173,784,339 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	173,563,072 - 173,609,837 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	173,380,510 - 173,427,275 (+)	NCBI		MGSCv36	mm8
Celera	2	179,705,544 - 179,751,066 (+)	NCBI		Celera
Cytogenetic Map	2	H4	NCBI
cM Map	2	97.37	NCBI

Vapb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	1,098,454 - 1,120,823 (-)	Ensembl
ChiLan1.0	NW_004955445	1,098,454 - 1,122,879 (-)	NCBI	ChiLan1.0	ChiLan1.0

VAPB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	64,147,622 - 64,209,801 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	64,140,742 - 64,202,911 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	54,736,035 - 54,798,155 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	56,010,782 - 56,071,185 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	56,010,782 - 56,064,363 (+)	Ensembl			panPan2	panpan1.1

VAPB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	43,182,158 - 43,238,019 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	43,182,196 - 43,231,336 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	42,428,808 - 42,484,615 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	44,048,066 - 44,104,061 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	44,048,014 - 44,098,692 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	43,152,527 - 43,208,360 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	43,270,720 - 43,326,518 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	43,929,924 - 43,985,979 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Vapb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	182,275,951 - 182,320,727 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936530	985,488 - 1,031,125 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936530	985,488 - 1,030,270 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VAPB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	58,594,749 - 58,644,914 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	58,594,749 - 58,644,925 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	65,806,107 - 65,856,325 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

VAPB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	5,686,294 - 5,740,855 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	5,687,611 - 5,740,740 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	53,733,097 - 53,795,120 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vapb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	24,716,716 - 24,766,480 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624741	24,716,835 - 24,767,806 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Vapb
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	144,197,379 - 144,242,591 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	271
Count of miRNA genes:	164
Interacting mature miRNAs:	199
Transcripts:	ENSRNOT00000007554
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161492708	189428310	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1300161	Rf10	Renal function QTL 10	3.57		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	3	181611379	189428310	Rat
8552791	Vie2	Viral induced encephalitis QTL 2	4.1		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	3	166376089	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	161799270	187311134	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1598854	Memor10	Memory QTL 10	2		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	3	166376089	189428310	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
22	13	81	212	91	90	59	157	59	6	481	281	22	190	111	124	31	34	34

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_021847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF086631	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC065576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213731	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000007554 ⟹ ENSRNOP00000007554

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	182,954,249 - 182,992,034 (+)	Ensembl
mRatBN7.2 Ensembl	3	162,535,905 - 162,573,763 (+)	Ensembl
Rnor_6.0 Ensembl	3	171,832,500 - 171,868,647 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000122080 ⟹ ENSRNOP00000106660

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	182,954,240 - 183,028,619 (+)	Ensembl

RefSeq Acc Id:

NM_021847 ⟹ NP_068619

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	182,954,247 - 182,997,018 (+)	NCBI
mRatBN7.2	3	162,535,974 - 162,578,747 (+)	NCBI
Rnor_6.0	3	171,832,558 - 171,868,449 (+)	NCBI
Rnor_5.0	3	177,890,856 - 177,931,543 (+)	NCBI
RGSC_v3.4	3	164,632,388 - 164,669,187 (+)	RGD
Celera	3	161,718,437 - 161,754,637 (+)	RGD

Sequence:

show sequence

ATGGCGAAGGTGGAGCAGGTCCTGAGTCTCGAGCCACAGCACGAGCTCAAGTTCCGAGGTCCCT
TCACTGATGTTGTCACTACCAACCTAAAGCTGGGCAACCCGACAGACCGGAACGTGTGTTTCAA
AGTGAAGACCACAGCGCCGCGCAGGTACTGCGTGCGGCCCAACAGTGGGGTCATTGATGCCGGG
GCCTCTCTCAATGTGTCTGTGATGTTACAGCCTTTCGATTATGACCCCAATGAGAAAAGTAAAC
ACAAGTTTATGGTTCAGTCTATGTTTGCTCCGCCCGACACTTCCGATATGGAGGCAGTATGGAA
GGAGGCAAAACCGGAAGACCTTATGGATTCAAAACTTAGATGTGTGTTTGAATTGCCAGCAGAA
AACGCTAAACCACATGATGTAGAAATAAATAAAATTATGCCTACAAGTGCATCCAAGACAGAAG
CACCGGTGGCCGCCAAGCCCCTCACATCGCCCCTTGATGACGCGGAAGTAAAGAAGGTGATGGA
AGAGTGCAGGCGGCTGCAGGGGGAGGTGCAGAGGCTTCGGGAGGAGAGCAGGCAGCTCAAGGAA
GAAGACGGGCTTCGGGCGAGGAAGGCACTGCCGAGCAACAGCCCCATGGCGGCTCTGGCTGCCA
GCGGGAAGGAGGAGGGCCTCAGCGCGCGGCTGCTGGCTCTGGTGGTGCTGTTCTTTATTGTTGG
GGTCATTATAGGGAAGATCGCCTTGTAG

hide sequence

RefSeq Acc Id:

XM_006235706 ⟹ XP_006235768

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	182,954,884 - 182,992,034 (+)	NCBI
mRatBN7.2	3	162,536,616 - 162,578,738 (+)	NCBI
Rnor_6.0	3	171,833,018 - 171,871,042 (+)	NCBI
Rnor_5.0	3	177,890,856 - 177,931,543 (+)	NCBI

Sequence:

show sequence

ATGTGTGTATTCATATTTCTATTCACTAATTTTAAGGTCCAGAAAGCAACAGGGTCCGTGCCCA
GCCTGTTCCTTGCTTCGTTGCATATTTTGAGTCATGAGACTGGGCACTGGAGGCCTATAAAGCT
CAACAACCTAAGCAAGATGGCGGCAGGCGGCTGGAAGTACTGGGAAGGGAAGGATGAAGTTGGA
CTCAATGGAGGTCCCTTCACTGATGTTGTCACTACCAACCTAAAGCTGGGCAACCCGACAGACC
GGAACGTGTGTTTCAAAGTGAAGACCACAGCGCCGCGCAGGTACTGCGTGCGGCCCAACAGTGG
GGTCATTGATGCCGGGGCCTCTCTCAATGTGTCTGTGATGTTACAGCCTTTCGATTATGACCCC
AATGAGAAAAGTAAACACAAGTTTATGGTTCAGTCTATGTTTGCTCCGCCCGACACTTCCGATA
TGGAGGCAGTATGGAAGGAGGCAAAACCGGAAGACCTTATGGATTCAAAACTTAGATGTGTGTT
TGAATTGCCAGCAGAAAACGCTAAACCACATGATGTAGAAATAAATAAAATTATGCCTACAAGT
GCATCCAAGACAGAAGCACCGGTGGCCGCCAAGCCCCTCACATCGCCCCTTGATGACGCGGAAG
TAAAGAAGGTGATGGAAGAGTGCAGGCGGCTGCAGGGGGAGGTGCAGAGGCTTCGGGAGGAGAG
CAGGCAGCTCAAGGAAGAAGACGGGCTTCGGGCGAGGAAGGCACTGCCGAGCAACAGCCCCATG
GCGGCTCTGGCTGCCAGCGGGAAGGAGGAGGGCCTCAGCGCGCGGCTGCTGGCTCTGGTGGTGC
TGTTCTTTATTGTTGGGGTCATTATAGGGAAGATCGCCTTGTAGAGGCCGCATGCAGAGGACGG
CAGACTGGATGGACGGATCTACCACACCATGGGATTTAAATTTATCATAACCATGCGTAAACAG
AAATTAATGTATGACGGCATCTCACAGGTCTTGCCTTTAAATATCCCTCCCCATGCACACACAA
ATGCACACAAATATAGCATAATATAACGATCTTTTAGAGAGTTGAAGATGTGTAGGAAATGGAT
GGGGAAGGACGGTCTATTGCTGAAGGACGGACAGACGGATGGACGCCATGATTAGCCTTAGTGG
CATCTTGTAGCTTGTCACGTCATTCGGGTAGGCCTGGGCACATGTTGCTAGATCACCTCTCTTA
AAGCAAGAAGCTCTTCCTCACATGCTGGGGCTGGCCCATGGGAGCGGGGTCCTTCAAGGTGGGG
TGTGCTGTCTTTTCTTACCCAGGTAGCTTCCCCAGGCCTGCTCTTTGTCCAGGCACCGAGATCT
CCTCAGGCCTACAGAGCTGCAAGAGCCAAAGTGCATTGCACAGCGGCCACGTCTGTACCCTGTA
GGTCGTGTGGGAGAGACATGAGTAGAGCGATGGATCCAGCATGGGGAAATCAAAGTCTGTGCTC
TGTTCTCTTGAAGGGACCAAGCTAAATTACTGTTGGTTCGAGTCGTGAGACCAAGCTGTTATCA
GTGATGGGTGATGCGTATTTAGCCTATTTCATGAATTTCATCTCGTGTTTCTGCTGCCACCAGA
GCACAGGCAGTGAGTGCTGCAGCCTGTCAGTCACCTGTGCTACAGACCACCAGTGAGGAGCCAC
TGCTGCCATGGGCTCTGTGGCTCTCAGGTCTGGAGCTCTGAGGGGTGGGGAGGTTCTGAGTCAG
GAAGTGTCCTGTTGTAGGTCAGTAGCAGCTGTCCTGAGGAGGGACGGACATTCTTTGTGATGAC
AGTCAGCTCTGGACTACCCAGCCTTCTAGGCTGTTTTTCCCCTCTCTCCCCTGTCACTCATCCT
TCTAGAACACAGGCCAGGTCTGACCTGCCTGCCTCAGGATGAATGAGTCAGGCAGCGGAGGGTG
AAGGGCATAGAGGGGGTAGGGTGGGGGTGGGGGAACCCCTCAGCAAATCCATCTGCTGGTGATG
AAGAGTCTTGACTGTGAATTAATTTCATGCCATAAAAGACCGATCCAGTTCTGCTCAACTATGT
AGCATCTTAAAGGAAGAGATTAAAATAAAGCCCCAAATTAAGAGTCCCTTTGTCGTTTTGTCGA
ATTTGCCGTGTGTGGGGTTACTATCAGTCATCATTAGCGCGCAATGGAAGGCTGATTTCAAAAT
GAGCTCTATCAGCGGCAAACACATGTGTAATGATTTGACTCTGCACACATCTGTGTGCACGCGC
ACACACACATATATTACTATTACTTTTATCATTATATTTTTGGTTGGCCTCCGCTTAACAGCAG
GAGCCATCTCAGGCTGGCTACCCTTCCCCTTCCGTGACCTTGGCGTGACCTTCGGTGACAGGCC
TGGGTCTGTGAGGACAAACACATCTTAAGGAAGACCGGCCTCGACACCAGGGCCCACATTGCTG
CTGTGCCTGAGTAGCCAGCTGGGACCGGAGACCGCTGAGGTGGCGCTGGGCGGTAAGCAGCCCT
GGTCTGCCCTGGTTAGTGAGTTTCCAGATCCTTCCCATGCACCTGAGGAAGACGATGCACGGCT
GAACAGAGAGCTCCGAGCTGTTACCTTGCTTGCCTTGGTGGCCGAGGTTCAGCAGTCTAAGGTG
CTGACAATGATCCCTGCTGCTCTCGAGAACAGAGTCACTCAGGGCCTCTAACAGGACCTGAGGT
GTCAACCAGCTCTATGACCCAGGAGCCAGGGTCTGCAAGTGTTCTTAAGGGATGGCTCTGTGTG
CCAGGAAAGCTCTTGAGAAGCATAGCCAGCTGCCGAGATTAAAGCGTGTCTGGAAGCTGCCGTG
GCTAGGGCCATGGAAGGTGATTGTGTGTCCGACGTCAGAATGCTCTCCGTGGGCCAGAGGTTGT
AGACATACCTGCTGTAGCAGCAACAACAAAACCTCGAGATACAAAGGTACCTTCCTTTGGCCCT
CAGGAGCCCTTCCTCGGAGGGATGATGGTCCAAGTGTGGTAGTTGTTGGGGCTTCTTGACCAAG
GGGACAGTGGGAACTCTAGGGAGATTAGCAAGGCAGAGTGGGTAATTCTCCGAGTTACCCCGTC
ACTAAAGAATGCTGGAAGAGAGGTGTCGGCAAGAAGAGTATTTACACGTGGGCCTCTCAAGAGA
GCCGTGCATATTTGGGGGGTCCTTTCTGAAAATTTCAGAGCAGAAAAACCTGAGTAAGGTACAG
AGAAGGTGAACGTTACTCTTTGCCCCACAAGTCTGCTGTCTCCAGAGAGGACAGAGTCAGGAGT
TCTGGAAGGCATGAAGCTAAGAGCTAGCAGGACAGCAGCCACGAAGCAGCCGGGCAGGTCCTTC
ATGGTCACAGGGCCTGCTGCTGCTCCTCCCCGTTGGGTGTCCTGGTGTTGGAAGCCCCTGCTAC
AGTGCTCACAGGGACACAGTGGCAGAGTCCCACCAACTATTGATTCAATTTCCAAGCCGATAGT
TTAAGCCCGGAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_068619	(Get FASTA)	NCBI Sequence Viewer
	XP_006235768	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD13580	(Get FASTA)	NCBI Sequence Viewer
	AAH65576	(Get FASTA)	NCBI Sequence Viewer
	EDL85103	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007554
	ENSRNOP00000007554.2
	ENSRNOP00000106660
GenBank Protein	Q9Z269	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_068619 ⟸ NM_021847

- UniProtKB:

Q9Z269 (UniProtKB/Swiss-Prot), A6KL13 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGVIDAG
ASLNVSVMLQPFDYDPNEKSKHKFMVQSMFAPPDTSDMEAVWKEAKPEDLMDSKLRCVFELPAE
NAKPHDVEINKIMPTSASKTEAPVAAKPLTSPLDDAEVKKVMEECRRLQGEVQRLREESRQLKE
EDGLRARKALPSNSPMAALAASGKEEGLSARLLALVVLFFIVGVIIGKIAL

hide sequence

RefSeq Acc Id:

XP_006235768 ⟸ XM_006235706

- Peptide Label:

isoform X1

- Sequence:

show sequence

MCVFIFLFTNFKVQKATGSVPSLFLASLHILSHETGHWRPIKLNNLSKMAAGGWKYWEGKDEVG
LNGGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGVIDAGASLNVSVMLQPFDYDP
NEKSKHKFMVQSMFAPPDTSDMEAVWKEAKPEDLMDSKLRCVFELPAENAKPHDVEINKIMPTS
ASKTEAPVAAKPLTSPLDDAEVKKVMEECRRLQGEVQRLREESRQLKEEDGLRARKALPSNSPM
AALAASGKEEGLSARLLALVVLFFIVGVIIGKIAL

hide sequence

Ensembl Acc Id:

ENSRNOP00000007554 ⟸ ENSRNOT00000007554

Ensembl Acc Id:

ENSRNOP00000106660 ⟸ ENSRNOT00000122080

Protein Domains

MSP

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9Z269-F1-model_v2	AlphaFold	Q9Z269	1-243	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692716

Promoter ID:

EPDNEW_R3241

Type:

initiation region

Name:

Vapb_1

Description:

VAMP associated protein B and C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	171,832,442 - 171,832,502	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:68326	AgrOrtholog
BioCyc Gene	G2FUF-46485	BioCyc
Ensembl Genes	ENSRNOG00000005331	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000007554	ENTREZGENE
	ENSRNOT00000007554.5	UniProtKB/Swiss-Prot
	ENSRNOT00000122080	ENTREZGENE
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:5598396	IMAGE-MGC_LOAD
InterPro	Ig-like_fold	UniProtKB/Swiss-Prot
	MSP_dom	UniProtKB/Swiss-Prot
	PapD-like_sf	UniProtKB/Swiss-Prot
	VAP	UniProtKB/Swiss-Prot
KEGG Report	rno:60431	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72459	IMAGE-MGC_LOAD
NCBI Gene	60431	ENTREZGENE
PANTHER	PTHR10809	UniProtKB/Swiss-Prot
	VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN B/C	UniProtKB/Swiss-Prot
Pfam	Motile_Sperm	UniProtKB/Swiss-Prot
PhenoGen	Vapb	PhenoGen
PIRSF	VAMP-associated	UniProtKB/Swiss-Prot
PROSITE	MSP	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000005331	RatGTEx
Superfamily-SCOP	SSF49354	UniProtKB/Swiss-Prot
UniProt	A0ABK0LLY4_RAT	UniProtKB/TrEMBL
	A6KL13	ENTREZGENE, UniProtKB/TrEMBL
	Q9Z269	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-22	Vapb	VAMP associated protein B and C	Vapb	VAMP (vesicle-associated membrane protein)-associated protein B and C	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-12-15	Vapb	VAMP (vesicle-associated membrane protein)-associated protein B and C	Vapb	vesicle-associated membrane protein, associated protein B and C	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Vapb	vesicle-associated membrane protein, associated protein B and C			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_homology	88% amino acid identity to human homolog	61779

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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