Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Larp4 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Larp4 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of LARP4 mRNA | CTD | PMID:22206623 | Larp4 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of LARP4 mRNA | CTD | PMID:17942748 | Larp4 | Rat | 17beta-estradiol | affects expression | ISO | LARP4 (Homo sapiens) | 6480464 | Estradiol affects the expression of LARP4 mRNA | CTD | PMID:22574217 | Larp4 | Rat | 17beta-estradiol | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Estradiol results in increased expression of LARP4 mRNA | CTD | PMID:19167446|PMID:31614463 | Larp4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Larp4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LARP4 mRNA | CTD | PMID:19770486 | Larp4 | Rat | 2-methylcholine | affects expression | ISO | LARP4 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of LARP4 mRNA | CTD | PMID:21179406 | Larp4 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Larp4 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of LARP4 mRNA | CTD | PMID:26251327 | Larp4 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | bisphenol S results in increased expression of LARP4 mRNA | CTD | PMID:39298647 | Larp4 | Rat | acrolein | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... | CTD | PMID:32699268 | Larp4 | Rat | acrylamide | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of LARP4 mRNA | CTD | PMID:32763439 | Larp4 | Rat | aflatoxin B1 | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of LARP4 mRNA | CTD | PMID:19770486 | Larp4 | Rat | alpha-pinene | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... | CTD | PMID:32699268 | Larp4 | Rat | arsane | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Larp4 | Rat | arsenic atom | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Larp4 | Rat | arsenite(3-) | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | arsenite results in increased expression of LARP4 protein | CTD | PMID:37955338 | Larp4 | Rat | benzo[a]pyrene | affects methylation | ISO | LARP4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LARP4 promoter | CTD | PMID:27901495 | Larp4 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of LARP4 mRNA | CTD | PMID:19150397 | Larp4 | Rat | beta-lapachone | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of LARP4 mRNA | CTD | PMID:38218311 | Larp4 | Rat | beta-naphthoflavone | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | beta-Naphthoflavone results in increased expression of LARP4 protein | CTD | PMID:39638853 | Larp4 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Larp4 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of LARP4 mRNA | CTD | PMID:33754040 | Larp4 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LARP4 mRNA | CTD | PMID:32145629 | Larp4 | Rat | bisphenol F | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | bisphenol F results in increased expression of LARP4 mRNA | CTD | PMID:38685157 | Larp4 | Rat | cadmium dichloride | decreases expression | ISO | Larp4 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of LARP4 mRNA | CTD | PMID:24982889 | Larp4 | Rat | caffeine | affects phosphorylation | ISO | LARP4 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of LARP4 protein | CTD | PMID:35688186 | Larp4 | Rat | carbon nanotube | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of LARP4 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681 | Larp4 | Rat | chlorpyrifos | decreases expression | ISO | Larp4 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of LARP4 mRNA | CTD | PMID:37019170 | Larp4 | Rat | chromium(6+) | affects expression | ISO | Larp4 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of LARP4 mRNA | CTD | PMID:28472532 | Larp4 | Rat | cobalt dichloride | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of LARP4 mRNA | CTD | PMID:19376846 | Larp4 | Rat | copper(II) sulfate | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of LARP4 mRNA | CTD | PMID:19549813 | Larp4 | Rat | coumarin | increases phosphorylation | ISO | LARP4 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of LARP4 protein | CTD | PMID:35688186 | Larp4 | Rat | crocidolite asbestos | decreases expression | ISO | Larp4 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of LARP4 mRNA | CTD | PMID:29279043 | Larp4 | Rat | CU-O LINKAGE | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | cupric oxide results in increased expression of LARP4 mRNA | CTD | PMID:22077320 | Larp4 | Rat | deoxynivalenol | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | deoxynivalenol results in increased expression of LARP4 protein | CTD | PMID:39638853 | Larp4 | Rat | dorsomorphin | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Larp4 | Rat | doxorubicin | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of LARP4 mRNA | CTD | PMID:29803840 | Larp4 | Rat | entinostat | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | entinostat results in increased expression of LARP4 mRNA | CTD | PMID:26272509 | Larp4 | Rat | entinostat | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Larp4 | Rat | enzyme inhibitor | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Larp4 | Rat | folic acid | decreases expression | ISO | Larp4 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of LARP4 mRNA | CTD | PMID:25629700 | Larp4 | Rat | FR900359 | affects phosphorylation | ISO | LARP4 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of LARP4 protein | CTD | PMID:37730182 | Larp4 | Rat | geldanamycin | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of LARP4 mRNA | CTD | PMID:26705709 | Larp4 | Rat | hydrogen peroxide | affects expression | ISO | LARP4 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of LARP4 mRNA | CTD | PMID:21179406 | Larp4 | Rat | hydrogen peroxide | multiple interactions | ISO | Larp4 (Mus musculus) | 6480464 | [Hydrogen Peroxide co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased phosphorylation of LARP4 protein | CTD | PMID:31494107 | Larp4 | Rat | isotretinoin | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of LARP4 mRNA | CTD | PMID:20436886 | Larp4 | Rat | ivermectin | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of LARP4 protein | CTD | PMID:32959892 | Larp4 | Rat | manganese atom | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Larp4 | Rat | manganese(0) | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Larp4 | Rat | manganese(II) chloride | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Larp4 | Rat | mercury dichloride | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Larp4 | Rat | Nivalenol | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | nivalenol results in increased expression of LARP4 protein | CTD | PMID:39638853 | Larp4 | Rat | ozone | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... | CTD | PMID:32699268 | Larp4 | Rat | paracetamol | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of LARP4 mRNA | CTD | PMID:21420995 | Larp4 | Rat | pentachlorophenol | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of LARP4 mRNA | CTD | PMID:23892564 | Larp4 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of LARP4 mRNA | CTD | PMID:27153767 | Larp4 | Rat | phenobarbital | affects expression | ISO | Larp4 (Mus musculus) | 6480464 | Phenobarbital affects the expression of LARP4 mRNA | CTD | PMID:23091169 | Larp4 | Rat | progesterone | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Progesterone results in increased expression of LARP4 mRNA | CTD | PMID:18070364 | Larp4 | Rat | SB 431542 | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Larp4 | Rat | senecionine | decreases expression | ISO | Larp4 (Mus musculus) | 6480464 | senecionine results in decreased expression of LARP4 protein | CTD | PMID:35357534 | Larp4 | Rat | silver atom | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Silver results in increased expression of LARP4 mRNA | CTD | PMID:26014281 | Larp4 | Rat | silver(0) | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Silver results in increased expression of LARP4 mRNA | CTD | PMID:26014281 | Larp4 | Rat | sodium arsenate | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of LARP4 mRNA | CTD | PMID:21795629|PMID:30953684 | Larp4 | Rat | sodium arsenite | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of LARP4 mRNA | CTD | PMID:38568856 | Larp4 | Rat | sodium arsenite | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of LARP4 protein | CTD | PMID:30528433 | Larp4 | Rat | sodium arsenite | multiple interactions | ISO | LARP4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Larp4 | Rat | sulindac | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Sulindac results in increased expression of LARP4 mRNA | CTD | PMID:11906190 | Larp4 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of LARP4 mRNA | CTD | PMID:31150632 | Larp4 | Rat | tetrachloromethane | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of LARP4 mRNA | CTD | PMID:31919559 | Larp4 | Rat | thapsigargin | increases expression | ISO | Larp4 (Mus musculus) | 6480464 | Thapsigargin results in increased expression of LARP4 protein | CTD | PMID:24648495 | Larp4 | Rat | thimerosal | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of LARP4 mRNA | CTD | PMID:27188386 | Larp4 | Rat | titanium dioxide | decreases methylation | ISO | Larp4 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of LARP4 gene | CTD | PMID:35295148 | Larp4 | Rat | titanium dioxide | increases methylation | ISO | Larp4 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of LARP4 promoter | CTD | PMID:35295148 | Larp4 | Rat | trichostatin A | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of LARP4 mRNA | CTD | PMID:24935251 | Larp4 | Rat | triphenyl phosphate | affects expression | ISO | LARP4 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of LARP4 mRNA | CTD | PMID:37042841 | Larp4 | Rat | valproic acid | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LARP4 mRNA | CTD | PMID:23179753 | Larp4 | Rat | valproic acid | decreases expression | ISO | LARP4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of LARP4 mRNA | CTD | PMID:28001369 | Larp4 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of LARP4 mRNA | CTD | PMID:23555832 | Larp4 | Rat | vorinostat | increases expression | ISO | LARP4 (Homo sapiens) | 6480464 | vorinostat results in increased expression of LARP4 mRNA | CTD | PMID:27188386 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















