Igsf1 (immunoglobulin superfamily, member 1) - Rat Genome Database

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Gene: Igsf1 (immunoglobulin superfamily, member 1) Rattus norvegicus
Analyze
Symbol: Igsf1
Name: immunoglobulin superfamily, member 1
RGD ID: 631402
Description: Enables coreceptor activity. Predicted to be involved in immune response-regulating signaling pathway; negative regulation of activin receptor signaling pathway; and regulation of DNA-templated transcription. Predicted to be located in extracellular region. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in IGSF1 deficiency syndrome. Orthologous to human IGSF1 (immunoglobulin superfamily member 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: immunoglobulin superfamily member 1; Inhbp; inhibin binding protein; inhibin-binding protein; MGC156568
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X133,947,717 - 133,963,154 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX133,947,429 - 133,962,962 (-)EnsemblGRCr8
mRatBN7.2X129,069,891 - 129,085,331 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX129,069,896 - 129,085,139 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX131,189,352 - 131,204,593 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X134,766,404 - 134,781,645 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X132,286,844 - 132,302,050 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X136,792,637 - 136,808,107 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX136,792,643 - 136,807,885 (-)Ensemblrn6Rnor6.0
Rnor_5.0X136,852,218 - 136,867,621 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X136,291,193 - 136,306,435 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX127,999,795 - 128,015,037 (-)NCBICelera
RGSC_v3.1X136,364,625 - 136,379,868 (-)NCBI
Cytogenetic MapXq36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(S)-nicotine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
butanal  (ISO)
caffeine  (ISO)
CGP 52608  (ISO)
choline  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glycidol  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
levonorgestrel  (ISO)
methylmercury chloride  (ISO)
morphine  (ISO)
nickel dichloride  (ISO)
nicotine  (ISO)
okadaic acid  (ISO)
organophosphorus compound  (EXP)
paracetamol  (ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
phytoestrogen  (ISO)
propanal  (ISO)
quercetin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (EXP)
testosterone undecanoate  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triticonazole  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Inhibin binding protein in rats: alternative transcripts and regulation in the pituitary across the estrous cycle. Bernard DJ and Woodruff TK, Mol Endocrinol 2001 Apr;15(4):654-67.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11266516   PMID:12477932   PMID:26163525   PMID:28686733  


Genomics

Comparative Map Data
Igsf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X133,947,717 - 133,963,154 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX133,947,429 - 133,962,962 (-)EnsemblGRCr8
mRatBN7.2X129,069,891 - 129,085,331 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX129,069,896 - 129,085,139 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX131,189,352 - 131,204,593 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X134,766,404 - 134,781,645 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X132,286,844 - 132,302,050 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X136,792,637 - 136,808,107 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX136,792,643 - 136,807,885 (-)Ensemblrn6Rnor6.0
Rnor_5.0X136,852,218 - 136,867,621 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X136,291,193 - 136,306,435 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX127,999,795 - 128,015,037 (-)NCBICelera
RGSC_v3.1X136,364,625 - 136,379,868 (-)NCBI
Cytogenetic MapXq36NCBI
IGSF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X131,273,506 - 131,289,457 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX131,273,506 - 131,578,899 (-)Ensemblhg38GRCh38
GRCh37X130,407,480 - 130,423,280 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X130,235,161 - 130,250,936 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X130,143,676 - 130,148,790NCBI
CeleraX130,793,906 - 130,809,827 (-)NCBICelera
Cytogenetic MapXq26.1NCBI
HuRefX119,813,192 - 119,829,114 (-)NCBIHuRef
CHM1_1X130,319,050 - 130,334,972 (-)NCBICHM1_1
T2T-CHM13v2.0X129,597,609 - 129,613,560 (-)NCBIT2T-CHM13v2.0
Igsf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X48,871,413 - 48,886,798 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX48,871,413 - 48,886,626 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X49,782,536 - 49,797,907 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX49,782,536 - 49,797,749 (-)Ensemblmm10GRCm38
MGSCv37X47,135,713 - 47,150,922 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X46,027,171 - 46,042,366 (-)NCBIMGSCv36mm8
CeleraX37,219,207 - 37,234,409 (-)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX26.06NCBI
Igsf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554733,699,517 - 3,715,514 (+)Ensembl
ChiLan1.0NW_0049554733,702,471 - 3,715,506 (+)NCBIChiLan1.0ChiLan1.0
IGSF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X130,700,734 - 130,716,554 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X130,704,343 - 130,720,164 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X120,406,725 - 120,422,636 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X130,714,056 - 130,729,963 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX130,714,061 - 130,729,963 (-)EnsemblpanPan2panpan1.1
IGSF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X102,359,980 - 102,376,838 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX102,359,986 - 102,377,018 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX88,533,700 - 88,550,251 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X104,215,865 - 104,232,428 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX104,215,952 - 104,232,561 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X101,630,820 - 101,647,378 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X103,479,801 - 103,496,290 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X103,259,023 - 103,275,352 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Igsf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X100,569,085 - 100,584,539 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936479402,957 - 418,400 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936479402,957 - 418,400 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGSF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX107,674,972 - 107,691,141 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X107,674,966 - 108,050,736 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X123,690,822 - 123,706,956 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IGSF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X106,486,902 - 106,536,622 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX106,486,765 - 106,503,310 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606543,911,738 - 43,927,738 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igsf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479710,780,306 - 10,795,724 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479710,780,294 - 10,795,750 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Igsf1
93 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:63
Count of miRNA genes:50
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000010325
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X120028026141353710Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X120028026141353710Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat

Markers in Region
AI227702  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X129,070,018 - 129,070,235 (+)MAPPERmRatBN7.2
Rnor_6.0X136,792,765 - 136,792,981NCBIRnor6.0
Rnor_5.0X136,852,346 - 136,852,562UniSTSRnor5.0
RGSC_v3.4X136,291,315 - 136,291,531UniSTSRGSC3.4
CeleraX127,999,917 - 128,000,133UniSTS
Cytogenetic MapXq36UniSTS
PMC162213P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X129,070,251 - 129,071,028 (+)MAPPERmRatBN7.2
Rnor_6.0X136,792,998 - 136,793,774NCBIRnor6.0
Rnor_5.0X136,852,579 - 136,853,355UniSTSRnor5.0
RGSC_v3.4X136,291,548 - 136,292,324UniSTSRGSC3.4
CeleraX128,000,150 - 128,000,926UniSTS
Cytogenetic MapXq36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 11 67 158 90 86 58 23 58 6 277 122 10 137 79 92 28 12 12

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_175763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC097866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF322216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF322217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000010325   ⟹   ENSRNOP00000010325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX133,947,720 - 133,962,962 (-)Ensembl
mRatBN7.2 EnsemblX129,069,897 - 129,085,139 (-)Ensembl
Rnor_6.0 EnsemblX136,792,643 - 136,807,885 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094119   ⟹   ENSRNOP00000097633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX133,947,429 - 133,962,962 (-)Ensembl
mRatBN7.2 EnsemblX129,069,896 - 129,085,139 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113410   ⟹   ENSRNOP00000081942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX133,947,720 - 133,962,962 (-)Ensembl
mRatBN7.2 EnsemblX129,069,897 - 129,082,621 (-)Ensembl
RefSeq Acc Id: NM_175763   ⟹   NP_786939
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,720 - 133,962,962 (-)NCBI
mRatBN7.2X129,069,897 - 129,085,139 (-)NCBI
Rnor_6.0X136,792,643 - 136,807,885 (-)NCBI
Rnor_5.0X136,852,218 - 136,867,621 (-)NCBI
RGSC_v3.4X136,291,193 - 136,306,435 (-)RGD
CeleraX127,999,795 - 128,015,037 (-)RGD
Sequence:
RefSeq Acc Id: XM_006257557   ⟹   XP_006257619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,154 (-)NCBI
mRatBN7.2X129,069,891 - 129,085,331 (-)NCBI
Rnor_6.0X136,792,637 - 136,808,107 (-)NCBI
Rnor_5.0X136,852,218 - 136,867,621 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257558   ⟹   XP_006257620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,044 (-)NCBI
mRatBN7.2X129,069,891 - 129,085,221 (-)NCBI
Rnor_6.0X136,792,637 - 136,807,932 (-)NCBI
Rnor_5.0X136,852,218 - 136,867,621 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257559   ⟹   XP_006257621
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,044 (-)NCBI
mRatBN7.2X129,069,891 - 129,085,221 (-)NCBI
Rnor_6.0X136,792,637 - 136,807,932 (-)NCBI
Rnor_5.0X136,852,218 - 136,867,621 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257560   ⟹   XP_006257622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,044 (-)NCBI
mRatBN7.2X129,069,891 - 129,085,221 (-)NCBI
Rnor_6.0X136,792,637 - 136,807,932 (-)NCBI
Rnor_5.0X136,852,218 - 136,867,621 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257561   ⟹   XP_006257623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,045 (-)NCBI
mRatBN7.2X129,069,891 - 129,085,221 (-)NCBI
Rnor_6.0X136,792,637 - 136,807,932 (-)NCBI
Rnor_5.0X136,852,218 - 136,867,621 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008773563   ⟹   XP_008771785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,044 (-)NCBI
mRatBN7.2X129,069,891 - 129,085,221 (-)NCBI
Rnor_6.0X136,792,637 - 136,807,932 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099678   ⟹   XP_038955606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,958,063 - 133,963,044 (-)NCBI
mRatBN7.2X129,080,240 - 129,085,221 (-)NCBI
RefSeq Acc Id: XM_063279959   ⟹   XP_063136029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,154 (-)NCBI
RefSeq Acc Id: XM_063279960   ⟹   XP_063136030
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,154 (-)NCBI
RefSeq Acc Id: XM_063279961   ⟹   XP_063136031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,044 (-)NCBI
RefSeq Acc Id: XM_063279962   ⟹   XP_063136032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,154 (-)NCBI
RefSeq Acc Id: XM_063279963   ⟹   XP_063136033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,044 (-)NCBI
RefSeq Acc Id: XM_063279964   ⟹   XP_063136034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,044 (-)NCBI
RefSeq Acc Id: XM_063279965   ⟹   XP_063136035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X133,947,717 - 133,963,045 (-)NCBI
RefSeq Acc Id: NP_786939   ⟸   NM_175763
- Peptide Label: precursor
- UniProtKB: A0JPK8 (UniProtKB/Swiss-Prot),   Q925N5 (UniProtKB/Swiss-Prot),   Q925N6 (UniProtKB/Swiss-Prot),   A6JMS1 (UniProtKB/TrEMBL),   A0A8L2Q5H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257619   ⟸   XM_006257557
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257620   ⟸   XM_006257558
- Peptide Label: isoform X2
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257621   ⟸   XM_006257559
- Peptide Label: isoform X5
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257623   ⟸   XM_006257561
- Peptide Label: isoform X9
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257622   ⟸   XM_006257560
- Peptide Label: isoform X7
- UniProtKB: A0A8I6ATC3 (UniProtKB/TrEMBL),   A0A8L2Q5H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008771785   ⟸   XM_008773563
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010325   ⟸   ENSRNOT00000010325
RefSeq Acc Id: XP_038955606   ⟸   XM_039099678
- Peptide Label: isoform X11
- UniProtKB: A6JMS3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000097633   ⟸   ENSRNOT00000094119
Ensembl Acc Id: ENSRNOP00000081942   ⟸   ENSRNOT00000113410
RefSeq Acc Id: XP_063136032   ⟸   XM_063279962
- Peptide Label: isoform X4
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136029   ⟸   XM_063279959
- Peptide Label: isoform X2
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136030   ⟸   XM_063279960
- Peptide Label: isoform X3
- UniProtKB: Q925N6 (UniProtKB/Swiss-Prot),   Q925N5 (UniProtKB/Swiss-Prot),   A0JPK8 (UniProtKB/Swiss-Prot),   A6JMS1 (UniProtKB/TrEMBL),   A0A8L2Q5H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136035   ⟸   XM_063279965
- Peptide Label: isoform X10
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136031   ⟸   XM_063279961
- Peptide Label: isoform X4
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136033   ⟸   XM_063279963
- Peptide Label: isoform X6
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136034   ⟸   XM_063279964
- Peptide Label: isoform X8
- UniProtKB: A0A8L2Q5H1 (UniProtKB/TrEMBL)
Protein Domains
Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q925N6-F1-model_v2 AlphaFold Q925N6 1-1320 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702016
Promoter ID:EPDNEW_R12540
Type:multiple initiation site
Name:Igsf1_1
Description:immunoglobulin superfamily, member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X136,807,885 - 136,807,945EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631402 AgrOrtholog
BioCyc Gene G2FUF-1113 BioCyc
Ensembl Genes ENSRNOG00000007600 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000010325 ENTREZGENE
  ENSRNOT00000094119 ENTREZGENE
  ENSRNOT00000113410 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig-like_Receptors_ImmuneReg UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
KEGG Report rno:302822 UniProtKB/Swiss-Prot
NCBI Gene 302822 ENTREZGENE
PANTHER MHC CLASS I NK CELL RECEPTOR UniProtKB/Swiss-Prot
  OSTEOCLAST-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR UniProtKB/Swiss-Prot
Pfam Ig_2 UniProtKB/Swiss-Prot
  Ig_3 UniProtKB/Swiss-Prot
PhenoGen Igsf1 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007600 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt A0A8I6ATC3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G6R3_RAT UniProtKB/TrEMBL
  A0A8L2Q5H1 ENTREZGENE, UniProtKB/TrEMBL
  A0JPK8 ENTREZGENE
  A6JMS1 ENTREZGENE, UniProtKB/TrEMBL
  A6JMS2_RAT UniProtKB/TrEMBL
  A6JMS3 ENTREZGENE, UniProtKB/TrEMBL
  IGSF1_RAT UniProtKB/Swiss-Prot
  Q925N5 ENTREZGENE
  Q925N6 ENTREZGENE
UniProt Secondary A0JPK8 UniProtKB/Swiss-Prot
  Q925N5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-11 Igsf1  immunoglobulin superfamily, member 1  Inhbp  inhibin binding protein  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_product member of the Ig superfamily 633133
gene_transcript transcript consists of two isoforms, one of which may be soluble 633133