Sp7 (Sp7 transcription factor) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Sp7 (Sp7 transcription factor) Rattus norvegicus
Analyze
Symbol: Sp7
Name: Sp7 transcription factor
RGD ID: 631377
Description: Predicted to enable DEAD/H-box RNA helicase binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to parathyroid hormone stimulus; cellular response to zinc ion starvation; and response to insulin. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 12. Orthologous to human SP7 (Sp7 transcription factor); INTERACTS WITH 5-formyltetrahydrofolic acid; ammonium chloride; arsenous acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: osterix; Osx; Transcription factor Sp7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,363,193 - 135,373,376 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7135,363,199 - 135,373,559 (-)EnsemblGRCr8
mRatBN7.27133,484,609 - 133,494,788 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,484,609 - 133,494,847 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7135,247,146 - 135,255,771 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,476,525 - 137,485,150 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,461,680 - 137,470,323 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,957,316 - 143,967,488 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,958,858 - 143,967,484 (-)Ensemblrn6Rnor6.0
Rnor_5.07141,753,826 - 141,762,790 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47141,109,771 - 141,118,397 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7129,919,226 - 129,927,844 (-)NCBICelera
RGSC_v3.17141,186,207 - 141,194,213 (-)NCBI
Cytogenetic Map7q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-di-tert-butylphenol  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methyladenine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-azacytidine  (ISO)
5-formyltetrahydrofolic acid  (EXP)
Actein  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
aluminium oxide  (ISO)
ammonium chloride  (EXP)
arsenous acid  (EXP)
atorvastatin calcium  (EXP)
aucubin  (ISO)
benzo[a]pyrene  (ISO)
berberine  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
cannabidiol  (ISO)
CHIR 99021  (ISO)
chromium(3+) trichloride  (ISO)
cobalt dichloride  (EXP,ISO)
cordycepin  (ISO)
D-glucose  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
disodium selenite  (ISO)
ellagic acid  (ISO)
erastin  (ISO)
ethyl 3,4-dihydroxybenzoate  (ISO)
fentin hydroxide  (ISO)
folic acid  (ISO)
fructose  (ISO)
fulvestrant  (EXP,ISO)
gamma-aminobutyric acid  (EXP)
gamma-Oryzanol (TN)  (EXP)
Ganoderic acid A  (ISO)
genistein  (ISO)
Ginkgoic acid  (ISO)
glucose  (ISO)
glycerol 1-phosphate  (ISO)
glycerol 2-phosphate  (ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
herbicide  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
ionomycin  (ISO)
isonicotinamide  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
menaquinone  (EXP)
metformin  (ISO)
methotrexate  (EXP)
microcystin-LR  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Morroniside  (ISO)
naringin  (EXP,ISO)
notoginsenoside R1  (ISO)
Octicizer  (ISO)
ozone  (ISO)
Picein  (ISO)
pioglitazone  (ISO)
prallethrin  (ISO)
protosappanin A  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quinoxyfen  (ISO)
resveratrol  (ISO)
Salidroside  (ISO)
SB 203580  (EXP)
simvastatin  (ISO)
sodium fluoride  (EXP,ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (EXP)
Theaflavin 3,3'-digallate  (ISO)
titanium dioxide  (ISO)
tributyl phosphate  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triphenylstannane  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tris(2-chloroethyl) phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
warfarin  (ISO)
XAV939  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Expression and function of osteogenic genes runt-related transcription factor 2 and osterix in orthodontic tooth movement in rats. Han J and He H, Int J Clin Exp Pathol. 2015 Sep 1;8(9):11895-900. eCollection 2015.
3. Increased expression of the receptor for activation of NF-kappaB and decreased runt-related transcription factor 2 expression in bone of rats with streptozotocin-induced diabetes. Hie M and Tsukamoto I, Int J Mol Med. 2010 Oct;26(4):611-8. doi: 10.3892/ijmm_00000506.
4. Zinc deficiency decreases osteoblasts and osteoclasts associated with the reduced expression of Runx2 and RANK. Hie M, etal., Bone. 2011 Dec;49(6):1152-9. doi: 10.1016/j.bone.2011.08.019. Epub 2011 Aug 26.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Nakashima K, etal., Cell 2002 Jan 11;108(1):17-29.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. [Histopathologic features of degenerative aortic valve and its mechanisms]. Sun J, etal., Zhonghua Yi Xue Za Zhi. 2013 Jan 22;93(4):280-4.
12. Parathyroid hormone regulates osterix and Runx2 mRNA expression predominantly through protein kinase A signaling in osteoblast-like cells. Wang BL, etal., J Endocrinol Invest. 2006 Feb;29(2):101-8. doi: 10.1007/BF03344081.
Additional References at PubMed
PMID:14604442   PMID:16041384   PMID:17303075   PMID:18270471   PMID:18272339   PMID:18471237   PMID:18932205   PMID:19124839   PMID:19822991   PMID:21806466   PMID:22009963   PMID:22886301  
PMID:23354182   PMID:25823394   PMID:26253417   PMID:28107808   PMID:30026585   PMID:30912295   PMID:32910396   PMID:33187585   PMID:34245724  


Genomics

Comparative Map Data
Sp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,363,193 - 135,373,376 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7135,363,199 - 135,373,559 (-)EnsemblGRCr8
mRatBN7.27133,484,609 - 133,494,788 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,484,609 - 133,494,847 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7135,247,146 - 135,255,771 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,476,525 - 137,485,150 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,461,680 - 137,470,323 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,957,316 - 143,967,488 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,958,858 - 143,967,484 (-)Ensemblrn6Rnor6.0
Rnor_5.07141,753,826 - 141,762,790 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47141,109,771 - 141,118,397 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7129,919,226 - 129,927,844 (-)NCBICelera
RGSC_v3.17141,186,207 - 141,194,213 (-)NCBI
Cytogenetic Map7q36NCBI
SP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,326,575 - 53,344,793 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,326,575 - 53,345,315 (-)Ensemblhg38GRCh38
GRCh371253,720,359 - 53,738,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,006,626 - 52,015,804 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341252,006,628 - 52,015,804NCBI
Celera1253,369,632 - 53,379,307 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,761,885 - 50,771,562 (-)NCBIHuRef
CHM1_11253,687,545 - 53,697,201 (-)NCBICHM1_1
T2T-CHM13v2.01253,292,290 - 53,310,533 (-)NCBIT2T-CHM13v2.0
Sp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,265,038 - 102,275,498 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,265,041 - 102,275,617 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3815102,356,603 - 102,367,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,356,606 - 102,367,182 (-)Ensemblmm10GRCm38
MGSCv3715102,187,608 - 102,196,702 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3615102,184,644 - 102,194,367 (-)NCBIMGSCv36mm8
Celera15104,514,244 - 104,523,282 (-)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.51NCBI
Sp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458583,981 - 602,856 (-)Ensembl
ChiLan1.0NW_004955458583,981 - 602,856 (-)NCBIChiLan1.0ChiLan1.0
SP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,849,740 - 40,859,601 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,846,505 - 40,856,578 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,409,055 - 35,427,871 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,191,091 - 36,209,494 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,199,673 - 36,209,494 (+)EnsemblpanPan2panpan1.1
SP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,878,612 - 1,887,063 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,880,424 - 1,887,679 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2744,365,530 - 44,382,281 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0271,871,509 - 1,888,303 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1271,889,794 - 1,906,485 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,874,976 - 1,891,740 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,766,164 - 44,782,966 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,544,586 - 62,554,293 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,612,060 - 10,619,628 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,610,542 - 10,613,335 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,543,534 - 18,565,776 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1518,541,368 - 18,566,668 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,978,684 - 19,002,387 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,436,976 - 49,456,741 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037196,611,275 - 196,624,212 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,436,115 - 1,456,609 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249041,436,390 - 1,444,996 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Sp7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11260,713,859 - 260,722,613 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:77
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000018828
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)7132099939137014596Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7119280025135560836Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7135371291137014596Rat

Markers in Region
D7Mit1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr87135,371,291 - 135,371,468 (+)Marker Load Pipeline
mRatBN7.27133,492,707 - 133,492,884 (+)MAPPERmRatBN7.2
Rnor_6.07143,965,415 - 143,965,591NCBIRnor6.0
Rnor_5.07141,760,721 - 141,760,897UniSTSRnor5.0
RGSC_v3.47141,116,327 - 141,116,504RGDRGSC3.4
RGSC_v3.47141,116,328 - 141,116,504UniSTSRGSC3.4
Celera7129,925,775 - 129,925,951UniSTS
RGSC_v3.17141,192,765 - 141,192,941RGD
RH 3.4 Map71065.7UniSTS
RH 3.4 Map71065.7RGD
RH 2.0 Map7799.2RGD
Cytogenetic Map7q36UniSTS
PMC151001P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27133,486,386 - 133,486,584 (+)MAPPERmRatBN7.2
Rnor_6.07143,959,094 - 143,959,291NCBIRnor6.0
Rnor_5.07141,754,402 - 141,754,599UniSTSRnor5.0
RGSC_v3.47141,110,007 - 141,110,204UniSTSRGSC3.4
Celera7129,919,462 - 129,919,659UniSTS
Cytogenetic Map7q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 3 23 140 40 37 23 14 23 5 134 57 11 128 42 81 14 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000018828   ⟹   ENSRNOP00000018828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7135,363,734 - 135,373,296 (-)Ensembl
mRatBN7.2 Ensembl7133,484,953 - 133,494,156 (-)Ensembl
Rnor_6.0 Ensembl7143,958,858 - 143,966,863 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081758   ⟹   ENSRNOP00000074457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7135,363,199 - 135,373,559 (-)Ensembl
mRatBN7.2 Ensembl7133,484,609 - 133,494,847 (-)Ensembl
Rnor_6.0 Ensembl7143,958,858 - 143,967,484 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000147039   ⟹   ENSRNOP00000110634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7135,363,296 - 135,373,354 (-)Ensembl
RefSeq Acc Id: NM_001037632   ⟹   NP_001032721
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,364,735 - 135,373,361 (-)NCBI
mRatBN7.27133,486,151 - 133,494,777 (-)NCBI
Rnor_6.07143,958,858 - 143,967,484 (-)NCBI
Rnor_5.07141,753,826 - 141,762,790 (-)NCBI
RGSC_v3.47141,109,771 - 141,118,397 (-)RGD
Celera7129,919,226 - 129,927,844 (-)RGD
Sequence:
RefSeq Acc Id: NM_181374   ⟹   NP_852039
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,364,735 - 135,372,740 (-)NCBI
mRatBN7.27133,486,151 - 133,494,156 (-)NCBI
Rnor_6.07143,958,858 - 143,966,863 (-)NCBI
Rnor_5.07141,753,826 - 141,762,790 (-)NCBI
RGSC_v3.47141,109,771 - 141,118,397 (-)RGD
Celera7129,919,226 - 129,927,223 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594791   ⟹   XP_017450280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,363,193 - 135,373,376 (-)NCBI
mRatBN7.27133,484,609 - 133,494,788 (-)NCBI
Rnor_6.07143,957,316 - 143,967,488 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001032721   ⟸   NM_001037632
- Peptide Label: isoform 1
- UniProtKB: Q6IMK1 (UniProtKB/TrEMBL),   Q811U1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_852039   ⟸   NM_181374
- Peptide Label: isoform 2
- UniProtKB: Q6IMK2 (UniProtKB/TrEMBL),   F7EYG4 (UniProtKB/TrEMBL),   Q811U1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450280   ⟸   XM_017594791
- Peptide Label: isoform X1
- UniProtKB: Q6IMK2 (UniProtKB/TrEMBL),   F7EYG4 (UniProtKB/TrEMBL),   Q811U1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018828   ⟸   ENSRNOT00000018828
Ensembl Acc Id: ENSRNOP00000074457   ⟸   ENSRNOT00000081758
Ensembl Acc Id: ENSRNOP00000110634   ⟸   ENSRNOT00000147039
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6IMK2-F1-model_v2 AlphaFold Q6IMK2 1-428 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695698
Promoter ID:EPDNEW_R6223
Type:multiple initiation site
Name:Sp7_1
Description:Sp7 transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07143,967,469 - 143,967,529EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631377 AgrOrtholog
BioCyc Gene G2FUF-31938 BioCyc
Ensembl Genes ENSRNOG00000014082 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018828.5 UniProtKB/TrEMBL
  ENSRNOT00000081758 ENTREZGENE
  ENSRNOT00000081758.3 UniProtKB/TrEMBL
  ENSRNOT00000147039.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:300260 UniProtKB/TrEMBL
NCBI Gene 300260 ENTREZGENE
PANTHER KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR SP7 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Sp7 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014082 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt F7EYG4 ENTREZGENE, UniProtKB/TrEMBL
  Q6IMK1 ENTREZGENE, UniProtKB/TrEMBL
  Q6IMK2 ENTREZGENE, UniProtKB/TrEMBL
  Q811U1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-11 Sp7  Sp7 transcription factor      Symbol and Name status set to approved 625702 APPROVED