Rbm10 (RNA binding motif protein 10) - Rat Genome Database

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Gene: Rbm10 (RNA binding motif protein 10) Rattus norvegicus
Analyze
Symbol: Rbm10
Name: RNA binding motif protein 10
RGD ID: 631366
Description: Enables single-stranded RNA binding activity. Involved in several processes, including cardiac muscle cell myoblast differentiation; negative regulation of RNA metabolic process; and negative regulation of cell growth involved in cardiac muscle cell development. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleolus. Biomarker of congestive heart failure. Human ortholog(s) of this gene implicated in TARP syndrome; colorectal cancer; lung adenocarcinoma; and lung cancer. Orthologous to human RBM10 (RNA binding motif protein 10); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: RNA-binding motif protein 10; RNA-binding protein 10; RNA-binding protein S1-1; S1-1 protein from liver
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X4,093,914 - 4,126,060 (-)NCBIGRCr8
mRatBN7.2X1,540,399 - 1,572,571 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX1,540,398 - 1,572,575 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX1,574,419 - 1,606,516 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X5,050,121 - 5,082,214 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X1,365,434 - 1,397,516 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X1,754,869 - 1,786,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX1,754,861 - 1,786,978 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X2,548,300 - 2,580,026 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X12,957,747 - 12,989,619 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X12,963,302 - 12,995,175 (-)NCBI
CeleraX2,104,400 - 2,136,451 (-)NCBICelera
Cytogenetic MapXq11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Original Reference(s)
Rbm10RatCardiomegaly  IEP 151667449protein:decreased expression:heartRGD 
Rbm10Ratcolorectal cancer onsetISORBM10 (Homo sapiens)151356979 RGD 
Rbm10Ratcongestive heart failure  IEP 151667449protein:decreased expression:heartRGD 
Rbm10Rathepatocellular carcinoma disease_progressionISORBM10 (Homo sapiens)151356975mRNA:decreased expression:liverRGD 
Rbm10Ratlung adenocarcinoma  ISORBM10 (Homo sapiens)151356983mRNA and protein:decreased expression:lungRGD 
Rbm10Ratlung adenocarcinoma  ISORBM10 (Homo sapiens)11097386DNA:missense mutations and protein-truncating variants: :multipleRGD 
Rbm10Ratlung adenocarcinoma  ISORBM10 (Homo sapiens)151356984 RGD 
Rbm10Ratlung cancer onsetISORBM10 (Homo sapiens)150429789 RGD 
Rbm10RatLymphatic Metastasis  ISORBM10 (Homo sapiens)151356993associated with lung adenocarcinoma and DNA:missense mutation:exon:p.R241C (c.763C>T) (human)RGD 
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Rbm10Ratautistic disorder  ISORBM10 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
Rbm10Ratcongenital disorder of glycosylation type IIm  ISORBM10 (Homo sapiens)8554872ClinVar Annotator: match by term: DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 22ClinVarPMID:28492532
Rbm10Ratgenetic disease  ISORBM10 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:15853797 more ...
Rbm10Ratimmune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome  ISORBM10 (Homo sapiens)8554872ClinVar Annotator: match by term: Insulin-dependent diabetes mellitus secretory diarrhea syndromeClinVarPMID:11137992 more ...
Rbm10Ratintellectual disability  ISORBM10 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:25741868 and PMID:28492532
Rbm10Ratneurodegeneration with brain iron accumulation 5  ISORBM10 (Homo sapiens)8554872ClinVar Annotator: match by term: Beta-propeller protein-associated neurodegenerationClinVarPMID:28492532
Rbm10RatNeurodevelopmental Disorders  ISORBM10 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Rbm10Ratsyndromic X-linked intellectual disability Lubs type  ISORBM10 (Homo sapiens)8554872ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs typeClinVarPMID:25741868
Rbm10RatTARP syndrome  ISORBM10 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:20451169 more ...
Rbm10RatX-linked epilepsy with variable learning disabilities and behavior disorders  ISORBM10 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:14985377 more ...
Rbm10RatX-linked severe congenital neutropenia  ISORBM10 (Homo sapiens)8554872ClinVar Annotator: match by term: X-linked severe congenital neutropeniaClinVarPMID:10698340 more ...
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Rbm10RatTARP syndrome  ISORBM10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
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Original Reference(s)
Rbm10RatTARP syndrome  ISORBM10 (Homo sapiens)7240710 OMIM 

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Rbm10Rat(1->4)-beta-D-glucan multiple interactionsISORbm10 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RBM10 mRNACTDPMID:36331819
Rbm10Rat14-Deoxy-11,12-didehydroandrographolide decreases expressionISORBM10 (Homo sapiens)648046414-deoxy-11 and 12-didehydroandrographolide results in decreased expression of RBM10 mRNACTDPMID:22101062
Rbm10Rat17beta-estradiol increases expressionISORbm10 (Mus musculus)6480464Estradiol results in increased expression of RBM10 mRNACTDPMID:39298647
Rbm10Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISORbm10 (Mus musculus)64804642 more ...CTDPMID:31388691
Rbm10Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORbm10 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of RBM10 mRNACTDPMID:19465110
Rbm10Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORbm10 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RBM10 mRNACTDPMID:21570461
Rbm10Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of RBM10 mRNACTDPMID:21346803
Rbm10Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of RBM10 mRNACTDPMID:21346803
Rbm10Rat2-hydroxypropanoic acid decreases expressionISORBM10 (Homo sapiens)6480464Lactic Acid results in decreased expression of RBM10 mRNACTDPMID:30851411
Rbm10Rat3,4-methylenedioxymethamphetamine increases expressionISORbm10 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of RBM10 mRNACTDPMID:20188158
Rbm10Rat4,4'-diaminodiphenylmethane increases expressionISORbm10 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of RBM10 mRNACTDPMID:18648102
Rbm10Rat4,4'-sulfonyldiphenol increases expressionISORbm10 (Mus musculus)6480464bisphenol S results in increased expression of RBM10 mRNACTDPMID:39298647
Rbm10Rat4,4'-sulfonyldiphenol increases expressionISORBM10 (Homo sapiens)6480464bisphenol S results in increased expression of RBM10 proteinCTDPMID:34186270
Rbm10Ratacrolein multiple interactionsISORBM10 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in decreased expression of RBM10 mRNACTDPMID:32845096
Rbm10Ratactinomycin D multiple interactionsISORBM10 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of RBM10 proteinCTDPMID:38460933
Rbm10Rataflatoxin B1 increases methylationISORBM10 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of RBM10 intronCTDPMID:30157460
Rbm10RatAflatoxin B2 alpha increases methylationISORBM10 (Homo sapiens)6480464aflatoxin B2 results in increased methylation of RBM10 intronCTDPMID:30157460
Rbm10Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of RBM10 mRNACTDPMID:16483693
Rbm10Rataristolochic acid A increases expressionISORBM10 (Homo sapiens)6480464aristolochic acid I results in increased expression of RBM10 mRNACTDPMID:33212167
Rbm10Ratarsane multiple interactionsISORBM10 (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of RBM10 mRNACTDPMID:39836092

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Biological Process
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Original Reference(s)
Rbm10Rat3'-UTR-mediated mRNA stabilization acts_upstream_of_or_withinIEAUniProtKB:Q99KG3 and ensembl:ENSMUSP000001110321600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Rat3'-UTR-mediated mRNA stabilization acts_upstream_of_or_withinISORbm10 (Mus musculus)1624291 PMID:19508861RGDPMID:19508861
Rbm10Ratcardiac muscle cell myoblast differentiation  IEP 151667450 RGD 
Rbm10RatmRNA splicing, via spliceosome involved_inIBAPANTHER:PTN000359040 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rbm10RatmRNA stabilization  IMP 151667451 RGD 
Rbm10Ratnegative regulation of cell growth involved in cardiac muscle cell development  IMP 151667449 RGD 
Rbm10Ratnegative regulation of cell population proliferation acts_upstream_of_or_withinIEAUniProtKB:Q99KG3 and ensembl:ENSMUSP000001110321600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratnegative regulation of cell population proliferation acts_upstream_of_or_withinISORbm10 (Mus musculus)1624291 PMID:19508861RGDPMID:19508861
Rbm10Ratnegative regulation of mRNA splicing, via spliceosome acts_upstream_of_or_withinIEAUniProtKB:Q99KG3 and ensembl:ENSMUSP000001110321600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratnegative regulation of mRNA splicing, via spliceosome acts_upstream_of_or_withinISORbm10 (Mus musculus)1624291 PMID:23636947RGDPMID:23636947
Rbm10Ratnegative regulation of ribosomal large subunit export from nucleus involved_inISORBM10 (Homo sapiens)1624291 PMID:35393574RGDPMID:35393574
Rbm10Ratnegative regulation of transcription by RNA polymerase II  IMP 151667451 RGD 
Rbm10Ratnegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:Q99KG3 and ensembl:ENSMUSP000001110321600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratnegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISORbm10 (Mus musculus)1624291 PMID:19508861RGDPMID:19508861
Rbm10Ratnegative regulation of vascular associated smooth muscle cell proliferation acts_upstream_of_or_withinISORbm10 (Mus musculus)1624291MGI:87964 PMID:19508861RGDPMID:19508861
Rbm10Ratnegative regulation of vascular associated smooth muscle cell proliferation acts_upstream_of_or_withinIEAUniProtKB:Q99KG3 and ensembl:ENSMUSP000001110321600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratpositive regulation of execution phase of apoptosis  IMP 151667451 RGD 
Rbm10Ratpositive regulation of vascular associated smooth muscle cell apoptotic process acts_upstream_of_or_withinIEAUniProtKB:Q99KG3 and ensembl:ENSMUSP000001110321600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratpositive regulation of vascular associated smooth muscle cell apoptotic process acts_upstream_of_or_withinISORbm10 (Mus musculus)1624291 PMID:19508861RGDPMID:19508861
Rbm10Ratregulation of vascular associated smooth muscle cell apoptotic process acts_upstream_of_or_withinISORbm10 (Mus musculus)1624291MGI:87964 PMID:19508861RGDPMID:19508861
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Cellular Component
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Original Reference(s)
Rbm10Ratnuclear speck located_inIEAUniProtKB:P98175 and ensembl:ENSP000003668291600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratnuclear speck located_inISORBM10 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Rbm10Ratnuclear speck located_inIEAUniProtKB:A0A0S2Z4W4 and ensembl:ENSP000003668291600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratnucleolus is_active_inISORBM10 (Homo sapiens)1624291 PMID:35393574RGDPMID:35393574
Rbm10Ratnucleus part_ofISORBM10 (Homo sapiens)1624291 PMID:28091594RGDPMID:28091594
Rbm10Ratnucleus located_inIEAUniProtKB:P98175 and ensembl:ENSP000003668291600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratnucleus is_active_inIBAMGI:1338037 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rbm10Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Rbm10Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Rbm10Ratnucleus located_inISORBM10 (Homo sapiens)1624291 RGDGO_REF:0000054
Rbm10Ratprotein-containing complex part_ofIEAUniProtKB:P98175 and ensembl:ENSP000003668291600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratprotein-containing complex part_ofISORBM10 (Homo sapiens)1624291UniProtKB:P52732 more ...RGDPMID:17707232
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Molecular Function
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Rbm10Ratidentical protein binding enablesIEAUniProtKB:P98175 and ensembl:ENSP000003668291600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratidentical protein binding enablesISORBM10 (Homo sapiens)1624291UniProtKB:P98175 and PMID:22365833RGDPMID:22365833
Rbm10Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Rbm10RatmiRNA binding enablesISSUniProtKB:P981751600115GO_REF:0000024UniProtGO_REF:0000024
Rbm10RatmiRNA binding enablesISORBM10 (Homo sapiens)1624291 PMID:28431233RGDPMID:28431233
Rbm10RatmiRNA binding enablesIEAUniProtKB:P98175 and ensembl:ENSP000003668291600115GO_REF:0000107EnsemblGO_REF:0000107
Rbm10Ratnucleic acid binding enablesIEAInterPro:IPR000467 and InterPro:IPR0359791600115GO_REF:0000002InterProGO_REF:0000002
Rbm10Ratprotein binding enablesISORBM10 (Homo sapiens)1624291UniProtKB:O15042 more ...RGDPMID:22365833 more ...
Rbm10RatRNA binding enablesIEAUniRule:UR0004146191600115GO_REF:0000104UniProtGO_REF:0000104
Rbm10RatRNA binding enablesIBAPANTHER:PTN000359040 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rbm10RatRNA binding enablesIEAInterPro:IPR0005041600115GO_REF:0000002InterProGO_REF:0000002
Rbm10RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
Rbm10Ratsingle-stranded RNA binding  IDA 1299361 RGD 
Rbm10Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
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Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Imielinski M, etal., Cell. 2012 Sep 14;150(6):1107-20. doi: 10.1016/j.cell.2012.08.029.
4. Molecular cloning of a RNA binding protein, S1-1. Inoue A, etal., Nucleic Acids Res 1996 Aug 1;24(15):2990-7.
5. Increased cell apoptosis in human lung adenocarcinoma and in vivo tumor growth inhibition by RBM10, a tumor suppressor gene. Ji Y, etal., Oncol Lett. 2017 Oct;14(4):4663-4669. doi: 10.3892/ol.2017.6765. Epub 2017 Aug 17.
6. RBM10 inhibits cell proliferation of lung adenocarcinoma via RAP1/AKT/CREB signalling pathway. Jin X, etal., J Cell Mol Med. 2019 Jun;23(6):3897-3904. doi: 10.1111/jcmm.14263. Epub 2019 Apr 6.
7. Differential downregulation of Rbm5 and Rbm10 during skeletal and cardiac differentiation. Loiselle JJ and Sutherland LC, In Vitro Cell Dev Biol Anim. 2014 Apr;50(4):331-9. doi: 10.1007/s11626-013-9708-z. Epub 2013 Nov 1.
8. A Splicing-Independent Function of RBM10 Controls Specific 3' UTR Processing to Regulate Cardiac Hypertrophy. Mohan N, etal., Cell Rep. 2018 Sep 25;24(13):3539-3553. doi: 10.1016/j.celrep.2018.08.077.
9. The heterogenous nuclear riboprotein S1-1 regulates AT1 receptor gene expression via transcriptional and posttranscriptional mechanisms. Mueller CF, etal., Arch Biochem Biophys. 2009 Aug 1;488(1):76-82. doi: 10.1016/j.abb.2009.06.002. Epub 2009 Jun 7.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive genomic profile of Chinese lung cancer patients and mutation characteristics of individuals resistant to icotinib/gefitinib. Shang Y, etal., Sci Rep. 2020 Nov 20;10(1):20243. doi: 10.1038/s41598-020-76791-y.
15. Germline Profiling and Molecular Characterization of Early Onset Metastatic Colorectal Cancer. Xu T, etal., Front Oncol. 2020 Oct 19;10:568911. doi: 10.3389/fonc.2020.568911. eCollection 2020.
16. A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis. Yin LL, etal., Oncol Lett. 2018 Nov;16(5):6283-6292. doi: 10.3892/ol.2018.9496. Epub 2018 Sep 24.
17. Protective effect of the RNA-binding protein RBM10 in hepatocellular carcinoma. Zhao Z, etal., Eur Rev Med Pharmacol Sci. 2020 Jun;24(11):6005-6013. doi: 10.26355/eurrev_202006_21494.
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PMID:17707232   PMID:22365833   PMID:22658674   PMID:23636947   PMID:28091594   PMID:28431233   PMID:35352799  



Rbm10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X4,093,914 - 4,126,060 (-)NCBIGRCr8
mRatBN7.2X1,540,399 - 1,572,571 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX1,540,398 - 1,572,575 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX1,574,419 - 1,606,516 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X5,050,121 - 5,082,214 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X1,365,434 - 1,397,516 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X1,754,869 - 1,786,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX1,754,861 - 1,786,978 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X2,548,300 - 2,580,026 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X12,957,747 - 12,989,619 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X12,963,302 - 12,995,175 (-)NCBI
CeleraX2,104,400 - 2,136,451 (-)NCBICelera
Cytogenetic MapXq11NCBI
RBM10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X47,145,221 - 47,186,813 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX47,145,221 - 47,186,813 (+)EnsemblGRCh38hg38GRCh38
GRCh37X47,004,620 - 47,046,212 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X46,889,575 - 46,931,156 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X46,760,884 - 46,802,465NCBI
CeleraX51,199,950 - 51,241,502 (+)NCBICelera
Cytogenetic MapXp11.3NCBI
HuRefX44,705,144 - 44,757,310 (+)NCBIHuRef
CHM1_1X47,036,374 - 47,077,701 (+)NCBICHM1_1
T2T-CHM13v2.0X46,554,946 - 46,596,509 (+)NCBIT2T-CHM13v2.0
Rbm10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X20,483,596 - 20,517,128 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX20,483,742 - 20,517,140 (+)EnsemblGRCm39 Ensembl
GRCm38X20,617,357 - 20,650,889 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX20,617,503 - 20,650,901 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X20,194,629 - 20,228,031 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X19,776,955 - 19,807,848 (+)NCBIMGSCv36mm8
CeleraX18,748,266 - 18,781,340 (+)NCBICelera
Cytogenetic MapXA1.3NCBI
cM MapX16.11NCBI
Rbm10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955516904,062 - 934,313 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955516904,852 - 934,313 (-)NCBIChiLan1.0ChiLan1.0
RBM10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X48,773,161 - 48,814,282 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X48,776,537 - 48,817,658 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X39,582,480 - 39,623,749 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X47,440,586 - 47,481,418 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX47,440,815 - 47,481,204 (+)Ensemblpanpan1.1panPan2
RBM10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X40,746,959 - 40,776,764 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX40,747,178 - 40,776,742 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX15,122,366 - 15,151,898 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X40,881,422 - 40,910,736 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX40,881,685 - 40,910,731 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X40,869,124 - 40,898,424 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X40,856,781 - 40,886,306 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X40,949,871 - 40,979,406 (+)NCBIUU_Cfam_GSD_1.0
Rbm10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X33,083,132 - 33,111,429 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650212,925,910 - 12,955,470 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650212,923,890 - 12,952,179 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBM10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX41,773,232 - 41,803,653 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X41,773,232 - 41,803,656 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X46,808,876 - 46,820,384 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RBM10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X44,339,653 - 44,373,509 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX44,339,877 - 44,373,339 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660769,597,361 - 9,631,993 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbm10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248873,923,986 - 3,957,133 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248873,921,934 - 3,953,739 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rbm10
53 total Variants

Predicted Target Of
Summary Value
Count of predictions:52
Count of miRNA genes:50
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000011317
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
70166Bp65Blood pressure QTL 655.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144797211374346Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat

UniSTS:479219  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X1,540,711 - 1,541,891 (+)MAPPERmRatBN7.2
Rnor_6.0X1,755,182 - 1,756,361NCBIRnor6.0
Rnor_5.0X2,548,613 - 2,549,792UniSTSRnor5.0
RGSC_v3.4X12,958,060 - 12,959,239UniSTSRGSC3.4
CeleraX2,104,713 - 2,105,892UniSTS
Cytogenetic MapXq12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000011317   ⟹   ENSRNOP00000011317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX1,540,411 - 1,572,543 (-)Ensembl
Rnor_6.0 EnsemblX1,754,869 - 1,786,978 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077453   ⟹   ENSRNOP00000072756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX1,540,398 - 1,555,600 (-)Ensembl
Rnor_6.0 EnsemblX1,754,861 - 1,784,807 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096592   ⟹   ENSRNOP00000084552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX1,540,411 - 1,572,575 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111814   ⟹   ENSRNOP00000090693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX1,540,402 - 1,572,061 (-)Ensembl
RefSeq Acc Id: NM_001414396   ⟹   NP_001401325
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X4,093,916 - 4,126,060 (-)NCBI
mRatBN7.2X1,540,401 - 1,572,548 (-)NCBI
RefSeq Acc Id: NM_152861   ⟹   NP_690600
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X4,093,914 - 4,126,024 (-)NCBI
mRatBN7.2X1,540,399 - 1,572,512 (-)NCBI
Rnor_6.0X1,754,869 - 1,786,973 (-)NCBI
Rnor_5.0X2,548,300 - 2,580,026 (-)NCBI
RGSC_v3.4X12,957,747 - 12,989,619 (-)RGD
CeleraX2,104,400 - 2,136,451 (-)RGD
Sequence:
RefSeq Acc Id: XM_039100025   ⟹   XP_038955953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X4,093,923 - 4,106,953 (-)NCBI
mRatBN7.2X1,540,401 - 1,553,434 (-)NCBI
RefSeq Acc Id: XM_039100026   ⟹   XP_038955954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X4,093,923 - 4,108,982 (-)NCBI
mRatBN7.2X1,540,401 - 1,555,470 (-)NCBI
RefSeq Acc Id: XM_063280281   ⟹   XP_063136351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X4,093,923 - 4,123,862 (-)NCBI
RefSeq Acc Id: XM_063280282   ⟹   XP_063136352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X4,093,923 - 4,123,862 (-)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_690600   ⟸   NM_152861
- Peptide Label: isoform 1
- UniProtKB: P70501 (UniProtKB/Swiss-Prot),   A6JZT5 (UniProtKB/TrEMBL),   A0A8I6A0D6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072756   ⟸   ENSRNOT00000077453
Ensembl Acc Id: ENSRNOP00000011317   ⟸   ENSRNOT00000011317
RefSeq Acc Id: XP_038955954   ⟸   XM_039100026
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038955953   ⟸   XM_039100025
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A0D6 (UniProtKB/TrEMBL)
C2H2-type   G-patch   RanBP2-type   RRM

Name Modeler Protein Id AA Range Protein Structure
AF-P70501-F1-model_v2 AlphaFold P70501 1-852 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701696
Promoter ID:EPDNEW_R12220
Type:multiple initiation site
Name:Rbm10_1
Description:RNA binding motif protein 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X1,787,009 - 1,787,069EPDNEW


1 to 40 of 44 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-3187 BioCyc
Ensembl Genes ENSRNOG00000008472 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011317 ENTREZGENE
  ENSRNOT00000011317.7 UniProtKB/Swiss-Prot
  ENSRNOT00000077453 ENTREZGENE
  ENSRNOT00000096592 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
  Zinc finger, RanBP2-type UniProtKB/Swiss-Prot
InterPro G_patch_dom UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  OCRE UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RBM10_OCRE UniProtKB/Swiss-Prot
  RBM10_RRM2 UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
  Znf_RanBP2 UniProtKB/Swiss-Prot
  Znf_RanBP2_sf UniProtKB/Swiss-Prot
KEGG Report rno:64510 UniProtKB/Swiss-Prot
NCBI Gene 64510 ENTREZGENE
PANTHER PTHR13948:SF4 UniProtKB/Swiss-Prot
  RNA-BINDING PROTEIN UniProtKB/Swiss-Prot
Pfam G-patch UniProtKB/Swiss-Prot
  OCRE UniProtKB/Swiss-Prot
  RRM_1 UniProtKB/Swiss-Prot
  zf-RanBP UniProtKB/Swiss-Prot
PhenoGen Rbm10 PhenoGen
PROSITE G_PATCH UniProtKB/Swiss-Prot
  RRM UniProtKB/Swiss-Prot
  ZF_RANBP2_1 UniProtKB/Swiss-Prot
  ZF_RANBP2_2 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008472 RatGTEx
SMART G_patch UniProtKB/Swiss-Prot
  RRM UniProtKB/Swiss-Prot
  ZnF_RBZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
  SSF90209 UniProtKB/Swiss-Prot
UniProt A0A0G2K3S6_RAT UniProtKB/TrEMBL
  A0A8I6A0D6 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 44 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Rbm10  RNA binding motif protein 10      Symbol and Name status set to approved 1299863 APPROVED