Hnrnpr (heterogeneous nuclear ribonucleoprotein R) - Rat Genome Database

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Pathways
Gene: Hnrnpr (heterogeneous nuclear ribonucleoprotein R) Rattus norvegicus
Analyze
Symbol: Hnrnpr
Name: heterogeneous nuclear ribonucleoprotein R
RGD ID: 631348
Description: Enables mRNA 3'-UTR binding activity. Involved in circadian rhythm and mRNA destabilization. Located in axon terminus; dendrite; and growth cone. Orthologous to human HNRNPR (heterogeneous nuclear ribonucleoprotein R); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Hnrpr
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Hnrnpr-ps2  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85153,826,482 - 153,872,272 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5153,826,692 - 153,858,344 (+)EnsemblGRCr8
mRatBN7.25148,542,999 - 148,574,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5148,543,044 - 148,574,867 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5151,240,600 - 151,272,452 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05153,014,891 - 153,046,743 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05152,996,900 - 153,028,752 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05154,668,194 - 154,699,967 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5154,668,179 - 154,699,966 (+)Ensemblrn6Rnor6.0
Rnor_5.05158,435,433 - 158,467,206 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45155,053,567 - 155,086,482 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5146,943,785 - 146,975,518 (+)NCBICelera
RGSC_v3.15155,063,605 - 155,096,519 (+)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
3',5'-cyclic UMP  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (EXP,ISO)
buspirone  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
choline  (ISO)
cobalt dichloride  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furfural  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
mercury dibromide  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (EXP)
nicotine  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl caffeate  (EXP)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sunitinib  (ISO)
testosterone enanthate  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors. Chen YI, etal., Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rhythmic serotonin N-acetyltransferase mRNA degradation is essential for the maintenance of its circadian oscillation. Kim TD, etal., Mol Cell Biol. 2005 Apr;25(8):3232-46.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. The expression pattern of heterogeneous nuclear ribonucleoprotein R in rat retina. Peng ZY, etal., Neurochem Res. 2009 Jun;34(6):1083-8. doi: 10.1007/s11064-008-9878-3. Epub 2008 Nov 18.
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? Rossoll W, etal., Hum Mol Genet 2002 Jan 1;11(1):93-105.
11. Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons. Rossoll W, etal., J Cell Biol. 2003 Nov 24;163(4):801-12. Epub 2003 Nov 17.
Additional References at PubMed
PMID:9421497   PMID:10734137   PMID:11991638   PMID:12477932   PMID:17289661   PMID:18197392   PMID:22658674   PMID:22681889   PMID:25002582   PMID:28131823  


Genomics

Comparative Map Data
Hnrnpr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85153,826,482 - 153,872,272 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5153,826,692 - 153,858,344 (+)EnsemblGRCr8
mRatBN7.25148,542,999 - 148,574,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5148,543,044 - 148,574,867 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5151,240,600 - 151,272,452 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05153,014,891 - 153,046,743 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05152,996,900 - 153,028,752 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05154,668,194 - 154,699,967 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5154,668,179 - 154,699,966 (+)Ensemblrn6Rnor6.0
Rnor_5.05158,435,433 - 158,467,206 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45155,053,567 - 155,086,482 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5146,943,785 - 146,975,518 (+)NCBICelera
RGSC_v3.15155,063,605 - 155,096,519 (+)NCBI
Cytogenetic Map5q36NCBI
HNRNPR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38123,304,688 - 23,344,284 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl123,303,771 - 23,344,358 (-)Ensemblhg38GRCh38
GRCh37123,631,181 - 23,670,777 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36123,508,863 - 23,543,440 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34123,381,581 - 23,416,090NCBI
Celera121,965,908 - 22,000,508 (-)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef121,888,335 - 21,922,947 (-)NCBIHuRef
CHM1_1123,748,964 - 23,783,552 (-)NCBICHM1_1
T2T-CHM13v2.0123,137,824 - 23,177,454 (-)NCBIT2T-CHM13v2.0
Hnrnpr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394136,038,230 - 136,086,758 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4136,038,253 - 136,086,758 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384136,310,942 - 136,345,981 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4136,310,942 - 136,359,447 (+)Ensemblmm10GRCm38
MGSCv374135,866,891 - 135,896,593 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364135,583,048 - 135,612,754 (+)NCBIMGSCv36mm8
Celera4134,504,233 - 134,541,867 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map468.4NCBI
Hnrnpr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554523,315,133 - 3,355,508 (-)Ensembl
ChiLan1.0NW_0049554523,318,536 - 3,354,725 (-)NCBIChiLan1.0ChiLan1.0
HNRNPR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21203,596,951 - 203,631,217 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11202,699,926 - 202,734,209 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0122,501,816 - 22,536,050 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1123,491,310 - 23,536,807 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl123,491,310 - 23,521,977 (-)EnsemblpanPan2panpan1.1
HNRNPR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1276,073,553 - 76,108,763 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl276,077,022 - 76,105,433 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha272,578,464 - 72,613,658 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0276,632,113 - 76,667,329 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl276,632,148 - 76,669,310 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1273,454,127 - 73,489,619 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,461,516 - 74,497,259 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,466,676 - 75,501,874 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hnrnpr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505842,706,668 - 42,742,983 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364748,531,434 - 8,567,767 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364748,531,434 - 8,567,734 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HNRNPR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl681,196,062 - 81,239,406 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1681,203,067 - 81,239,823 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2675,260,326 - 75,261,878 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HNRNPR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120109,325,850 - 109,357,624 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660336,963,189 - 6,997,405 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hnrnpr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247647,957,395 - 7,992,398 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247647,956,789 - 7,992,449 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Hnrnpr
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1121,891,008 - 21,923,276 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hnrnpr
196 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:473
Count of miRNA genes:232
Interacting mature miRNAs:286
Transcripts:ENSRNOT00000015971
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5149805999162987697Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
D5Rat57  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85153,890,625 - 153,890,773 (+)Marker Load Pipeline
mRatBN7.25148,607,142 - 148,607,290 (+)MAPPERmRatBN7.2
Rnor_6.05154,732,228 - 154,732,375NCBIRnor6.0
Rnor_5.05158,498,929 - 158,499,076UniSTSRnor5.0
RGSC_v3.45155,120,876 - 155,121,024RGDRGSC3.4
RGSC_v3.45155,120,877 - 155,121,024UniSTSRGSC3.4
Celera5147,007,863 - 147,007,992UniSTS
RGSC_v3.15155,130,916 - 155,131,063RGD
RH 3.4 Map51003.2UniSTS
RH 3.4 Map51003.2RGD
RH 2.0 Map5955.5RGD
FHH x ACI Map584.2699RGD
Cytogenetic Map5q36UniSTS
BF390061  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25148,582,708 - 148,582,902 (+)MAPPERmRatBN7.2
Rnor_6.05154,707,804 - 154,707,997NCBIRnor6.0
Rnor_5.05158,475,043 - 158,475,236UniSTSRnor5.0
RGSC_v3.45155,094,320 - 155,094,513UniSTSRGSC3.4
Celera5146,983,356 - 146,983,549UniSTS
RH 3.4 Map51003.5UniSTS
Cytogenetic Map5q36UniSTS
UniSTS:479130  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21204,419,595 - 204,420,133 (+)MAPPERmRatBN7.2
Rnor_6.01222,484,117 - 222,484,654NCBIRnor6.0
Rnor_5.01229,474,204 - 229,474,741UniSTSRnor5.0
RGSC_v3.41209,904,231 - 209,904,768UniSTSRGSC3.4
Celera1201,951,722 - 201,952,259UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_175603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010066404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010066405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY184814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000015971   ⟹   ENSRNOP00000015971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5153,826,692 - 153,858,344 (+)Ensembl
mRatBN7.2 Ensembl5148,543,044 - 148,574,867 (+)Ensembl
Rnor_6.0 Ensembl5154,668,179 - 154,699,966 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112913   ⟹   ENSRNOP00000091882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5153,829,709 - 153,857,704 (+)Ensembl
mRatBN7.2 Ensembl5148,546,226 - 148,574,223 (+)Ensembl
RefSeq Acc Id: NM_175603   ⟹   NP_783193
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,519 - 153,858,369 (+)NCBI
mRatBN7.25148,543,036 - 148,574,888 (+)NCBI
Rnor_6.05154,668,194 - 154,699,967 (+)NCBI
Rnor_5.05158,435,433 - 158,467,206 (+)NCBI
RGSC_v3.45155,053,567 - 155,086,482 (+)RGD
Celera5146,943,785 - 146,975,518 (+)RGD
Sequence:
RefSeq Acc Id: XM_039110146   ⟹   XP_038966074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,580 - 153,872,272 (+)NCBI
mRatBN7.25148,542,999 - 148,574,888 (+)NCBI
RefSeq Acc Id: XM_063287850   ⟹   XP_063143920
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,482 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287851   ⟹   XP_063143921
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,689 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287852   ⟹   XP_063143922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,827,146 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287853   ⟹   XP_063143923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,827,153 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287854   ⟹   XP_063143924
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,528 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287855   ⟹   XP_063143925
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,720 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287856   ⟹   XP_063143926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,741 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287857   ⟹   XP_063143927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,482 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287858   ⟹   XP_063143928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,482 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287859   ⟹   XP_063143929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,484 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287860   ⟹   XP_063143930
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,827,149 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287861   ⟹   XP_063143931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,482 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287862   ⟹   XP_063143932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,605 - 153,872,272 (+)NCBI
RefSeq Acc Id: XM_063287863   ⟹   XP_063143933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,482 - 153,848,968 (+)NCBI
RefSeq Acc Id: XR_010066404
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,482 - 153,856,879 (+)NCBI
RefSeq Acc Id: XR_010066405
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85153,826,482 - 153,853,790 (+)NCBI
RefSeq Acc Id: NP_783193   ⟸   NM_175603
- UniProtKB: Q566E4 (UniProtKB/TrEMBL),   F1LUZ6 (UniProtKB/TrEMBL),   Q811S1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015971   ⟸   ENSRNOT00000015971
RefSeq Acc Id: XP_038966074   ⟸   XM_039110146
- Peptide Label: isoform X7
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000091882   ⟸   ENSRNOT00000112913
RefSeq Acc Id: XP_063143920   ⟸   XM_063287850
- Peptide Label: isoform X1
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143931   ⟸   XM_063287861
- Peptide Label: isoform X6
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143928   ⟸   XM_063287858
- Peptide Label: isoform X4
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143927   ⟸   XM_063287857
- Peptide Label: isoform X3
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143933   ⟸   XM_063287863
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063143929   ⟸   XM_063287859
- Peptide Label: isoform X5
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143924   ⟸   XM_063287854
- Peptide Label: isoform X2
- UniProtKB: F1LUZ6 (UniProtKB/TrEMBL),   Q566E4 (UniProtKB/TrEMBL),   Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143932   ⟸   XM_063287862
- Peptide Label: isoform X1
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143921   ⟸   XM_063287851
- Peptide Label: isoform X1
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143925   ⟸   XM_063287855
- Peptide Label: isoform X2
- UniProtKB: F1LUZ6 (UniProtKB/TrEMBL),   Q566E4 (UniProtKB/TrEMBL),   Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143926   ⟸   XM_063287856
- Peptide Label: isoform X2
- UniProtKB: F1LUZ6 (UniProtKB/TrEMBL),   Q566E4 (UniProtKB/TrEMBL),   Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143922   ⟸   XM_063287852
- Peptide Label: isoform X1
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143930   ⟸   XM_063287860
- Peptide Label: isoform X5
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143923   ⟸   XM_063287853
- Peptide Label: isoform X1
- UniProtKB: Q811S1 (UniProtKB/TrEMBL)
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q566E4-F1-model_v2 AlphaFold Q566E4 1-632 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694170
Promoter ID:EPDNEW_R4695
Type:initiation region
Name:Hnrnpr_1
Description:heterogeneous nuclear ribonucleoprotein R
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05154,668,142 - 154,668,202EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631348 AgrOrtholog
BioCyc Gene G2FUF-39505 BioCyc
Ensembl Genes ENSRNOG00000011910 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015971 ENTREZGENE
  ENSRNOT00000015971.9 UniProtKB/TrEMBL
  ENSRNOT00000112913.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7315896 IMAGE-MGC_LOAD
InterPro hnRNP_Q_AcD UniProtKB/TrEMBL
  HnRNP_R/Q_splicing_fac UniProtKB/TrEMBL
  hnRNPR_RRM1 UniProtKB/TrEMBL
  hnRNPR_RRM2 UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
KEGG Report rno:319110 UniProtKB/TrEMBL
MGC_CLONE MGC:105294 IMAGE-MGC_LOAD
NCBI Gene 319110 ENTREZGENE
PANTHER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN UniProtKB/TrEMBL
Pfam hnRNP_Q_AcD UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PhenoGen Hnrnpr PhenoGen
PROSITE RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011910 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8I6GJB1_RAT UniProtKB/TrEMBL
  F1LUZ6 ENTREZGENE
  Q566E4 ENTREZGENE, UniProtKB/TrEMBL
  Q811S1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LUZ6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-25 Hnrnpr  heterogeneous nuclear ribonucleoprotein R  Hnrpr  heterogeneous nuclear ribonucleoprotein R  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-11 Hnrpr  heterogeneous nuclear ribonucleoprotein R      Symbol and Name status set to approved 625702 APPROVED