Cpg1 (candidate plasticity gene 1) - Rat Genome Database

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Gene: Cpg1 (candidate plasticity gene 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Cpg1
Name: candidate plasticity gene 1
RGD ID: 631343
Description: Involved in regulation of neuronal synaptic plasticity; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 4,4'-sulfonyldiphenol; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86124,041,902 - 124,053,895 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6124,041,902 - 124,053,895 (+)EnsemblGRCr8
mRatBN7.26118,312,220 - 118,324,213 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6118,312,220 - 118,324,213 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6118,463,698 - 118,475,682 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06118,760,517 - 118,772,501 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06118,095,376 - 118,107,360 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06123,034,304 - 123,046,297 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6123,034,304 - 123,046,297 (+)Ensemblrn6Rnor6.0
Rnor_5.06132,263,033 - 132,275,178 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46123,231,348 - 123,243,341 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6115,870,075 - 115,882,068 (+)NCBICelera
RGSC_v3.16123,235,094 - 123,247,088 (+)NCBI
Cytogenetic Map6q32NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Numerous candidate plasticity-related genes revealed by differential cDNA cloning. Nedivi E, etal., Nature 1993 Jun 24;363(6431):718-22.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Cpg1
44 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:70
Count of miRNA genes:60
Interacting mature miRNAs:62
Transcripts:ENSRNOT00000066469
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)699437079125323237Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 18 133 59 58 27 26 27 6 146 69 2 111 33 46 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000078938   ⟹   ENSRNOP00000073328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6124,041,902 - 124,053,895 (+)Ensembl
mRatBN7.2 Ensembl6118,312,220 - 118,324,213 (+)Ensembl
Rnor_6.0 Ensembl6123,034,304 - 123,046,297 (+)Ensembl
RefSeq Acc Id: NM_178104   ⟹   NP_835205
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86124,041,902 - 124,053,895 (+)NCBI
mRatBN7.26118,312,220 - 118,324,213 (+)NCBI
Rnor_6.06123,034,304 - 123,046,297 (+)NCBI
Rnor_5.06132,263,033 - 132,275,178 (+)NCBI
RGSC_v3.46123,231,348 - 123,243,341 (+)RGD
Celera6115,870,075 - 115,882,068 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_835205 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA51724 (Get FASTA)   NCBI Sequence Viewer  
  EDL81700 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073328
  ENSRNOP00000073328.1
RefSeq Acc Id: NP_835205   ⟸   NM_178104
- UniProtKB: Q08302 (UniProtKB/TrEMBL),   A6JEF6 (UniProtKB/TrEMBL),   A0A0G2K581 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073328   ⟸   ENSRNOT00000078938

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q08302-F1-model_v2 AlphaFold Q08302 1-94 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-36531 BioCyc
Ensembl Genes ENSRNOG00000060278 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078938 ENTREZGENE
  ENSRNOT00000078938.3 UniProtKB/TrEMBL
KEGG Report rno:299247 UniProtKB/TrEMBL
NCBI Gene 299247 ENTREZGENE
PhenoGen Cpg1 PhenoGen
RatGTEx ENSRNOG00000060278 RatGTEx
UniProt A0A0G2K581 ENTREZGENE, UniProtKB/TrEMBL
  A6JEF6 ENTREZGENE, UniProtKB/TrEMBL
  Q08302 ENTREZGENE
UniProt Secondary Q08302 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-11 Vnr7  candidate plasticity gene 1  Cpg1  Cpg1 protein  Name updated 625702 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_regulation expression induced by glutamate analogue kainate and activation of the NMDA (N-methyl-D-aspartate) receptor 632508