Lzts3 (leucine zipper tumor suppressor family member 3) - Rat Genome Database

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Gene: Lzts3 (leucine zipper tumor suppressor family member 3) Rattus norvegicus
Analyze
Symbol: Lzts3
Name: leucine zipper tumor suppressor family member 3
RGD ID: 631327
Description: Enables PDZ domain binding activity and protein self-association. Involved in protein homooligomerization; regulation of dendritic spine morphogenesis; and regulation of postsynapse assembly. Located in dendritic spine. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human LZTS3 (leucine zipper tumor suppressor family member 3); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leucine zipper putative tumor suppressor 3; leucine zipper, putative tumor suppressor family member 3; proSAP-interacting protein 1; Prosapip1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,303,378 - 138,313,645 (-)NCBIGRCr8
mRatBN7.23117,850,286 - 117,861,132 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,851,702 - 117,860,081 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3121,744,582 - 121,754,799 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,342,131 - 130,352,346 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,000,716 - 128,010,934 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,174,444 - 123,185,649 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,175,860 - 123,179,644 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,672,572 - 129,683,734 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,264,579 - 118,268,363 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,170,151 - 118,173,254 (-)NCBI
Celera3116,662,570 - 116,666,354 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytoskeleton  (IEA)
dendritic spine  (IBA,IDA,IEA)
glutamatergic synapse  (IDA,IEP,IMP)
postsynaptic density  (IDA,IEP)
synapse  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Bouwmeester T, etal., Nat Cell Biol 2004 Feb;6(2):97-105. Epub 2004 Jan 25.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The Shank3 Interaction Partner ProSAPiP1 Regulates Postsynaptic SPAR Levels and the Maturation of Dendritic Spines in Hippocampal Neurons. Reim D, etal., Front Synaptic Neurosci. 2016 May 24;8:13. doi: 10.3389/fnsyn.2016.00013. eCollection 2016.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. ProSAP-interacting protein 1 (ProSAPiP1), a novel protein of the postsynaptic density that links the spine-associated Rap-Gap (SPAR) to the scaffolding protein ProSAP2/Shank3. Wendholt D, etal., J Biol Chem. 2006 May 12;281(19):13805-16. Epub 2006 Mar 7.
Additional References at PubMed
PMID:17120053   PMID:26364583  


Genomics

Comparative Map Data
Lzts3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,303,378 - 138,313,645 (-)NCBIGRCr8
mRatBN7.23117,850,286 - 117,861,132 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,851,702 - 117,860,081 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3121,744,582 - 121,754,799 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,342,131 - 130,352,346 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,000,716 - 128,010,934 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,174,444 - 123,185,649 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,175,860 - 123,179,644 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,672,572 - 129,683,734 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,264,579 - 118,268,363 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,170,151 - 118,173,254 (-)NCBI
Celera3116,662,570 - 116,666,354 (-)NCBICelera
Cytogenetic Map3q36NCBI
LZTS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,162,617 - 3,173,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,162,617 - 3,173,549 (-)EnsemblGRCh38hg38GRCh38
GRCh37203,143,263 - 3,154,195 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,091,273 - 3,097,207 (-)NCBINCBI36Build 36hg18NCBI36
Build 34203,091,272 - 3,097,207NCBI
Celera203,205,231 - 3,211,165 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,091,031 - 3,097,003 (-)NCBIHuRef
CHM1_1203,143,306 - 3,149,240 (-)NCBICHM1_1
T2T-CHM13v2.0203,193,522 - 3,204,462 (-)NCBIT2T-CHM13v2.0
Lzts3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,474,685 - 130,484,764 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,474,759 - 130,484,723 (-)EnsemblGRCm39 Ensembl
GRCm382130,632,765 - 130,642,866 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,632,839 - 130,642,803 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,458,575 - 130,468,539 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,324,213 - 130,334,285 (-)NCBIMGSCv36mm8
Celera2131,857,390 - 131,867,607 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.24NCBI
Lzts3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,065,338 - 14,072,617 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,065,338 - 14,075,718 (-)NCBIChiLan1.0ChiLan1.0
LZTS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,129,943 - 4,140,949 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1204,126,762 - 4,137,774 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,248,955 - 3,259,932 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1203,011,611 - 3,022,582 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,011,611 - 3,022,573 (-)Ensemblpanpan1.1panPan2
LZTS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,111,188 - 18,122,246 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,117,723 - 18,120,428 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,940,272 - 17,950,683 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,530,804 - 18,541,218 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,531,201 - 18,541,054 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12418,124,487 - 18,134,901 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02418,237,097 - 18,247,509 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,564,415 - 18,574,829 (+)NCBIUU_Cfam_GSD_1.0
Lzts3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640167,106,923 - 167,116,423 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648515,538,337 - 15,548,148 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648515,538,302 - 15,547,778 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LZTS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,508,706 - 32,518,522 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,507,512 - 32,518,524 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,877,505 - 36,888,515 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LZTS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1233,835,361 - 33,845,948 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl233,835,012 - 33,839,895 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607110,667,679 - 10,679,140 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lzts3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,268,869 - 4,281,653 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,271,584 - 4,282,082 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lzts3
20 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:297
Count of miRNA genes:185
Interacting mature miRNAs:206
Transcripts:ENSRNOT00000028835
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 3 3 3 64 35 20
Low 1 43 54 38 19 38 8 11 10 21 11 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000028835   ⟹   ENSRNOP00000028835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3117,851,702 - 117,856,078 (-)Ensembl
Rnor_6.0 Ensembl3123,175,860 - 123,179,644 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101454   ⟹   ENSRNOP00000084706
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3117,851,702 - 117,860,081 (-)Ensembl
RefSeq Acc Id: NM_172022   ⟹   NP_742019
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,303,378 - 138,313,611 (-)NCBI
mRatBN7.23117,850,286 - 117,860,520 (-)NCBI
Rnor_6.03123,175,860 - 123,179,644 (-)NCBI
Rnor_5.03129,672,572 - 129,683,734 (-)NCBI
RGSC_v3.43118,264,579 - 118,268,363 (-)RGD
Celera3116,662,570 - 116,666,354 (-)RGD
Sequence:
RefSeq Acc Id: XM_006235009   ⟹   XP_006235071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,303,378 - 138,313,645 (-)NCBI
mRatBN7.23117,850,286 - 117,861,132 (-)NCBI
Rnor_6.03123,174,444 - 123,185,649 (-)NCBI
Rnor_5.03129,672,572 - 129,683,734 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235014   ⟹   XP_006235076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,303,378 - 138,308,645 (-)NCBI
mRatBN7.23117,850,286 - 117,855,556 (-)NCBI
Rnor_6.03123,174,444 - 123,179,663 (-)NCBI
Rnor_5.03129,672,572 - 129,683,734 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008762148   ⟹   XP_008760370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,303,378 - 138,313,270 (-)NCBI
mRatBN7.23117,850,286 - 117,860,193 (-)NCBI
Rnor_6.03123,174,444 - 123,184,365 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008762149   ⟹   XP_008760371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,303,378 - 138,313,273 (-)NCBI
mRatBN7.23117,850,286 - 117,860,196 (-)NCBI
Rnor_6.03123,174,444 - 123,184,366 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008762150   ⟹   XP_008760372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,303,378 - 138,313,272 (-)NCBI
mRatBN7.23117,850,286 - 117,860,195 (-)NCBI
Rnor_6.03123,174,444 - 123,184,366 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039104399   ⟹   XP_038960327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,303,378 - 138,308,608 (-)NCBI
mRatBN7.23117,850,286 - 117,855,516 (-)NCBI
RefSeq Acc Id: NP_742019   ⟸   NM_172022
- UniProtKB: Q8K1Q4 (UniProtKB/Swiss-Prot),   A6HQA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235071   ⟸   XM_006235009
- Peptide Label: isoform X4
- UniProtKB: Q8K1Q4 (UniProtKB/Swiss-Prot),   G3V8V8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235076   ⟸   XM_006235014
- Peptide Label: isoform X5
- UniProtKB: Q8K1Q4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008760371   ⟸   XM_008762149
- Peptide Label: isoform X2
- UniProtKB: Q8K1Q4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008760372   ⟸   XM_008762150
- Peptide Label: isoform X3
- UniProtKB: Q8K1Q4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008760370   ⟸   XM_008762148
- Peptide Label: isoform X1
- UniProtKB: Q8K1Q4 (UniProtKB/Swiss-Prot),   A0A8I5ZYI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028835   ⟸   ENSRNOT00000028835
RefSeq Acc Id: XP_038960327   ⟸   XM_039104399
- Peptide Label: isoform X5
- UniProtKB: Q8K1Q4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSRNOP00000084706   ⟸   ENSRNOT00000101454

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K1Q4-F1-model_v2 AlphaFold Q8K1Q4 1-703 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631327 AgrOrtholog
BioCyc Gene G2FUF-47846 BioCyc
Ensembl Genes ENSRNOG00000021231 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028835.4 UniProtKB/TrEMBL
  ENSRNOT00000101454.1 UniProtKB/TrEMBL
InterPro LZTS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:280670 UniProtKB/Swiss-Prot
NCBI Gene 280670 ENTREZGENE
PANTHER PTHR19354 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR19354:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Fez1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lzts3 PhenoGen
RatGTEx ENSRNOG00000021231 RatGTEx
UniProt A0A8I5ZYI8 ENTREZGENE, UniProtKB/TrEMBL
  A6HQA4 ENTREZGENE, UniProtKB/TrEMBL
  G3V8V8 ENTREZGENE, UniProtKB/TrEMBL
  LZTS3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-27 Lzts3  leucine zipper tumor suppressor family member 3  Lzts3  leucine zipper, putative tumor suppressor family member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-20 Lzts3  leucine zipper, putative tumor suppressor family member 3  Prosapip1  ProSAPiP1 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Prosapip1  ProSAPiP1 protein  ProSAPiP1    Symbol updated 1299863 APPROVED