Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of LZTS3 mRNA] | CTD | PMID:31150632 | 1,1-dichloroethene | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of LZTS3 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | multiple interactions | ISO | Lzts3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of LZTS3 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of LZTS3 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Lzts3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LZTS3 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LZTS3 mRNA | CTD | PMID:33387578 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of LZTS3 mRNA | CTD | PMID:20188158 | 4,4'-sulfonyldiphenol | increases methylation | ISO | Lzts3 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of LZTS3 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Lzts3 (Mus musculus) | 6480464 | bisphenol S affects the methylation of LZTS3 gene | CTD | PMID:31683443 | 4-hydroxyphenyl retinamide | increases expression | ISO | Lzts3 (Mus musculus) | 6480464 | Fenretinide results in increased expression of LZTS3 mRNA | CTD | PMID:28973697 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of LZTS3 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases methylation | ISO | LZTS3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of LZTS3 gene | CTD | PMID:27153756 | Aflatoxin B2 alpha | increases methylation | ISO | LZTS3 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of LZTS3 polyA tail | CTD | PMID:30157460 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of LZTS3 mRNA | CTD | PMID:16483693 | aristolochic acid A | increases expression | ISO | LZTS3 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of LZTS3 mRNA | CTD | PMID:33212167 | arsenite(3-) | increases methylation | ISO | LZTS3 (Homo sapiens) | 6480464 | arsenite results in increased methylation of LZTS3 promoter | CTD | PMID:23974009 | atrazine | increases expression | ISO | LZTS3 (Homo sapiens) | 6480464 | Atrazine results in increased expression of LZTS3 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | multiple interactions | ISO | Lzts3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of LZTS3 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | decreases methylation | ISO | LZTS3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of LZTS3 exon | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | LZTS3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LZTS3 promoter | CTD | PMID:27901495 | benzo[b]fluoranthene | multiple interactions | ISO | Lzts3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of LZTS3 mRNA | CTD | PMID:27858113 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LZTS3 mRNA | CTD | PMID:25181051 and PMID:32145629 | bisphenol A | increases expression | ISO | Lzts3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of LZTS3 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LZTS3 mRNA | CTD | PMID:30816183 more ... | bisphenol A | affects expression | ISO | LZTS3 (Homo sapiens) | 6480464 | bisphenol A affects the expression of LZTS3 mRNA | CTD | PMID:30903817 | carbon nanotube | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlordecone | increases expression | ISO | Lzts3 (Mus musculus) | 6480464 | Chlordecone results in increased expression of LZTS3 mRNA | CTD | PMID:33711761 | choline | multiple interactions | ISO | Lzts3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of LZTS3 gene | CTD | PMID:20938992 | chrysene | multiple interactions | ISO | Lzts3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of LZTS3 mRNA | CTD | PMID:27858113 | cisplatin | multiple interactions | ISO | LZTS3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of LZTS3 mRNA | CTD | PMID:27392435 | clofibrate | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of LZTS3 mRNA | CTD | PMID:23811191 | cocaine | multiple interactions | ISO | Lzts3 (Mus musculus) | 6480464 | FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LZTS3 mRNA] | CTD | PMID:18355967 | cocaine | increases expression | ISO | Lzts3 (Mus musculus) | 6480464 | Cocaine results in increased expression of LZTS3 mRNA | CTD | PMID:18355967 | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of LZTS3 mRNA | CTD | PMID:30556269 | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of LZTS3 mRNA | CTD | PMID:30556269 | cyclosporin A | increases expression | ISO | LZTS3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of LZTS3 mRNA | CTD | PMID:25562108 | ethanol | affects expression | ISO | Lzts3 (Mus musculus) | 6480464 | Ethanol affects the expression of LZTS3 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | Lzts3 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | FR900359 | decreases phosphorylation | ISO | LZTS3 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of LZTS3 protein | CTD | PMID:37730182 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of LZTS3 mRNA | CTD | PMID:33387578 | graphene oxide | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | graphene oxide analog results in decreased expression of LZTS3 mRNA | CTD | PMID:33227293 | L-methionine | multiple interactions | ISO | Lzts3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of LZTS3 gene | CTD | PMID:20938992 | lead(0) | affects expression | ISO | LZTS3 (Homo sapiens) | 6480464 | Lead affects the expression of LZTS3 mRNA | CTD | PMID:28903495 | paracetamol | increases expression | ISO | LZTS3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of LZTS3 mRNA | CTD | PMID:21420995 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of LZTS3 mRNA | CTD | PMID:33387578 | pirinixic acid | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of LZTS3 mRNA | CTD | PMID:23811191 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of LZTS3 mRNA | CTD | PMID:28903501 | silicon dioxide | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of LZTS3 mRNA | CTD | PMID:23221170 | sunitinib | decreases expression | ISO | LZTS3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of LZTS3 mRNA | CTD | PMID:31533062 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of LZTS3 mRNA | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of LZTS3 mRNA | CTD | PMID:31919559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of LZTS3 mRNA] | CTD | PMID:31150632 | tetraphene | multiple interactions | ISO | Lzts3 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of LZTS3 mRNA | CTD | PMID:27858113 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of LZTS3 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | Lzts3 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of LZTS3 mRNA | CTD | PMID:29264374 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of LZTS3 gene | CTD | PMID:27618143 | triptonide | increases expression | ISO | Lzts3 (Mus musculus) | 6480464 | triptonide results in increased expression of LZTS3 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | LZTS3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of LZTS3 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | LZTS3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LZTS3 mRNA | CTD | PMID:28001369 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of LZTS3 mRNA | CTD | PMID:22615374 | |