Rere (arginine-glutamic acid dipeptide repeats) - Rat Genome Database

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Gene: Rere (arginine-glutamic acid dipeptide repeats) Rattus norvegicus
Analyze
Symbol: Rere
Name: arginine-glutamic acid dipeptide repeats
RGD ID: 629475
Description: Predicted to enable transcription coactivator activity and transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and positive regulation of DNA-templated transcription. Predicted to act upstream of or within chromatin remodeling and nervous system development. Predicted to be located in PML body. Predicted to be part of histone deacetylase complex. Predicted to be active in nucleus. Orthologous to human RERE (arginine-glutamic acid dipeptide repeats); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: arginine-glutamic acid dipeptide (RE) repeats; arginine-glutamic acid dipeptide repeats protein; Arp; atrophin-1 related protein; atrophin-1-related protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85166,048,770 - 166,380,559 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5166,048,844 - 166,380,558 (+)EnsemblGRCr8
mRatBN7.25160,765,855 - 161,097,678 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5160,765,934 - 161,097,677 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5163,482,407 - 163,814,337 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05165,303,892 - 165,633,496 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05165,260,957 - 165,592,979 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05167,330,966 - 167,664,506 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5167,331,035 - 167,664,505 (+)Ensemblrn6Rnor6.0
Rnor_5.05170,960,573 - 171,292,513 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45167,440,122 - 167,777,271 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5159,022,463 - 159,353,516 (+)NCBICelera
RGSC_v3.15167,450,315 - 167,785,644 (+)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
butan-1-ol  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
clobetasol  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
ethanol  (ISO)
fipronil  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
miconazole  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
xylitol  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cellular_component  (ND)
histone deacetylase complex  (IEA,ISO)
nuclear body  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
PML body  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genotype-phenotype correlations in individuals with pathogenic RERE variants. Jordan VK, etal., Hum Mutat. 2018 May;39(5):666-675. doi: 10.1002/humu.23400. Epub 2018 Jan 25.
3. cDNA cloning and characterization of an atrophin-1 (DRPLA disease gene)-related protein. Khan FA, etal., Neurobiol Dis 1996 Apr;3(2):121-8.
4. RERE deficiency causes retinal and optic nerve atrophy through degeneration of retinal cells. Kim BJ and Scott DA, Dev Dyn. 2021 Oct;250(10):1398-1409. doi: 10.1002/dvdy.330. Epub 2021 Mar 29.
5. RERE deficiency contributes to the development of orofacial clefts in humans and mice. Kim BJ, etal., Hum Mol Genet. 2021 May 12;30(7):595-602. doi: 10.1093/hmg/ddab084.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8889548   PMID:14645126   PMID:15057822   PMID:17150957   PMID:24466353  


Genomics

Comparative Map Data
Rere
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85166,048,770 - 166,380,559 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5166,048,844 - 166,380,558 (+)EnsemblGRCr8
mRatBN7.25160,765,855 - 161,097,678 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5160,765,934 - 161,097,677 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5163,482,407 - 163,814,337 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05165,303,892 - 165,633,496 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05165,260,957 - 165,592,979 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05167,330,966 - 167,664,506 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5167,331,035 - 167,664,505 (+)Ensemblrn6Rnor6.0
Rnor_5.05170,960,573 - 171,292,513 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45167,440,122 - 167,777,271 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5159,022,463 - 159,353,516 (+)NCBICelera
RGSC_v3.15167,450,315 - 167,785,644 (+)NCBI
Cytogenetic Map5q36NCBI
RERE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3818,352,404 - 8,817,640 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl18,352,397 - 8,848,921 (-)Ensemblhg38GRCh38
GRCh3718,412,464 - 8,877,699 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3618,335,051 - 8,800,286 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3418,346,722 - 8,811,790NCBI
Celera17,520,570 - 7,986,441 (-)NCBICelera
Cytogenetic Map1p36.23NCBI
HuRef17,561,179 - 8,026,761 (-)NCBIHuRef
CHM1_118,401,786 - 8,867,545 (-)NCBICHM1_1
T2T-CHM13v2.017,885,246 - 8,351,098 (-)NCBIT2T-CHM13v2.0
Rere
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394150,365,372 - 150,706,423 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4150,366,103 - 150,706,423 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384150,281,511 - 150,621,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4150,281,646 - 150,621,966 (+)Ensemblmm10GRCm38
MGSCv374149,656,025 - 149,996,075 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364149,250,140 - 149,465,771 (+)NCBIMGSCv36mm8
Celera4152,556,963 - 152,899,017 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map481.34NCBI
Rere
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554864,443,723 - 4,695,800 (+)Ensembl
ChiLan1.0NW_0049554864,303,573 - 4,695,800 (+)NCBIChiLan1.0ChiLan1.0
RERE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21219,411,252 - 219,877,538 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11218,057,183 - 218,522,302 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v017,111,594 - 7,576,667 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.118,348,687 - 8,747,495 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl18,351,367 - 8,648,973 (-)EnsemblpanPan2panpan1.1
RERE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1561,868,288 - 62,249,009 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl561,868,685 - 62,215,973 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha561,877,331 - 62,286,365 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0562,085,105 - 62,495,227 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl562,087,296 - 62,495,288 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1562,084,029 - 62,493,986 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0561,948,407 - 62,357,291 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0562,352,661 - 62,762,441 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rere
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505832,193,393 - 32,496,551 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366232,678,638 - 2,942,216 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366232,678,627 - 2,942,387 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RERE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1668,954,766 - 69,258,855 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2663,443,116 - 63,522,403 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RERE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120122,946,759 - 123,408,428 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20123,109,364 - 123,408,631 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605426,963,344 - 27,436,567 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rere
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248183,388,149 - 3,648,634 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248183,255,835 - 3,648,634 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rere
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1110,133,598 - 10,467,723 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rere
1308 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:362
Count of miRNA genes:202
Interacting mature miRNAs:265
Transcripts:ENSRNOT00000024443
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5160111176171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5160071170172129029Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5156396728167181764Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5156289283171137955Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat

Markers in Region
SHGC-74183  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25161,095,599 - 161,095,773 (+)MAPPERmRatBN7.2
Rnor_6.05167,662,428 - 167,662,601NCBIRnor6.0
Rnor_5.05171,290,435 - 171,290,608UniSTSRnor5.0
RGSC_v3.45167,775,193 - 167,775,366UniSTSRGSC3.4
Celera5159,351,438 - 159,351,611UniSTS
Cytogenetic Map5q36UniSTS
BI276205  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25161,095,586 - 161,095,767 (+)MAPPERmRatBN7.2
Rnor_6.05167,662,415 - 167,662,595NCBIRnor6.0
Rnor_5.05171,290,422 - 171,290,602UniSTSRnor5.0
RGSC_v3.45167,775,180 - 167,775,360UniSTSRGSC3.4
Celera5159,351,425 - 159,351,605UniSTS
RH 3.4 Map51122.6UniSTS
Cytogenetic Map5q36UniSTS
RH127536  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25161,097,307 - 161,097,511 (+)MAPPERmRatBN7.2
Rnor_6.05167,664,136 - 167,664,339NCBIRnor6.0
Rnor_5.05171,292,143 - 171,292,346UniSTSRnor5.0
RGSC_v3.45167,776,901 - 167,777,104UniSTSRGSC3.4
Celera5159,353,146 - 159,353,349UniSTS
Cytogenetic Map5q36UniSTS
RH143046  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25160,791,029 - 160,791,236 (+)MAPPERmRatBN7.2
Rnor_6.05167,356,697 - 167,356,903NCBIRnor6.0
Rnor_5.05170,986,235 - 170,986,441UniSTSRnor5.0
RGSC_v3.45167,465,162 - 167,465,368UniSTSRGSC3.4
Celera5159,047,517 - 159,047,723UniSTS
RH 3.4 Map51122.1UniSTS
Cytogenetic Map5q36UniSTS
AI548909  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25161,097,434 - 161,097,524 (+)MAPPERmRatBN7.2
Rnor_6.05167,664,263 - 167,664,352NCBIRnor6.0
Rnor_5.05171,292,270 - 171,292,359UniSTSRnor5.0
RGSC_v3.45167,777,028 - 167,777,117UniSTSRGSC3.4
Celera5159,353,273 - 159,353,362UniSTS
RH 3.4 Map51121.7UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI113241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW920332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA511326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB328253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB728130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK470955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U44091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000024443   ⟹   ENSRNOP00000024443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5166,048,844 - 166,380,558 (+)Ensembl
mRatBN7.2 Ensembl5160,765,934 - 161,097,677 (+)Ensembl
Rnor_6.0 Ensembl5167,331,035 - 167,664,505 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095232   ⟹   ENSRNOP00000085727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5166,048,844 - 166,380,558 (+)Ensembl
mRatBN7.2 Ensembl5160,765,934 - 161,097,677 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103362   ⟹   ENSRNOP00000089254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5166,252,561 - 166,380,555 (+)Ensembl
mRatBN7.2 Ensembl5160,969,273 - 161,097,677 (+)Ensembl
RefSeq Acc Id: NM_053885   ⟹   NP_446337
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,048,844 - 166,380,559 (+)NCBI
mRatBN7.25160,765,934 - 161,097,678 (+)NCBI
Rnor_6.05167,331,035 - 167,664,506 (+)NCBI
Rnor_5.05170,960,573 - 171,292,513 (+)NCBI
RGSC_v3.45167,440,122 - 167,777,271 (+)RGD
Celera5159,022,463 - 159,353,516 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239438   ⟹   XP_006239500
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,048,772 - 166,380,556 (+)NCBI
mRatBN7.25160,765,857 - 161,097,678 (+)NCBI
Rnor_6.05167,330,966 - 167,664,506 (+)NCBI
Rnor_5.05170,960,573 - 171,292,513 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239441   ⟹   XP_006239503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,248,508 - 166,380,556 (+)NCBI
mRatBN7.25160,966,551 - 161,097,678 (+)NCBI
Rnor_6.05167,533,306 - 167,664,506 (+)NCBI
Rnor_5.05170,960,573 - 171,292,513 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764198   ⟹   XP_008762420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,048,770 - 166,380,556 (+)NCBI
mRatBN7.25160,765,855 - 161,097,678 (+)NCBI
Rnor_6.05167,330,966 - 167,664,506 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764199   ⟹   XP_008762421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,137,073 - 166,380,556 (+)NCBI
mRatBN7.25160,853,228 - 161,097,678 (+)NCBI
Rnor_6.05167,419,646 - 167,664,506 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764200   ⟹   XP_008762422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,048,773 - 166,380,556 (+)NCBI
mRatBN7.25160,765,858 - 161,097,678 (+)NCBI
Rnor_6.05167,330,967 - 167,664,506 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764201   ⟹   XP_008762423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,048,771 - 166,380,556 (+)NCBI
mRatBN7.25160,765,855 - 161,097,678 (+)NCBI
Rnor_6.05167,330,966 - 167,664,506 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063287068   ⟹   XP_063143138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,088,656 - 166,380,556 (+)NCBI
RefSeq Acc Id: XM_063287069   ⟹   XP_063143139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,060,838 - 166,380,556 (+)NCBI
RefSeq Acc Id: XM_063287070   ⟹   XP_063143140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,137,074 - 166,380,556 (+)NCBI
RefSeq Acc Id: NP_446337   ⟸   NM_053885
- UniProtKB: Q62901 (UniProtKB/Swiss-Prot),   A6IUD6 (UniProtKB/TrEMBL),   A0A8I6A4P7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239500   ⟸   XM_006239438
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A4P7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239503   ⟸   XM_006239441
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A9U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762423   ⟸   XM_008764201
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A4P7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762420   ⟸   XM_008764198
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A4P7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762422   ⟸   XM_008764200
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A4P7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762421   ⟸   XM_008764199
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A4P7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024443   ⟸   ENSRNOT00000024443
Ensembl Acc Id: ENSRNOP00000089254   ⟸   ENSRNOT00000103362
Ensembl Acc Id: ENSRNOP00000085727   ⟸   ENSRNOT00000095232
RefSeq Acc Id: XP_063143139   ⟸   XM_063287069
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A4P7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143138   ⟸   XM_063287068
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A4P7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143140   ⟸   XM_063287070
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A4P7 (UniProtKB/TrEMBL)
Protein Domains
BAH   ELM2   SANT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62901-F1-model_v2 AlphaFold Q62901 1-1559 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694281
Promoter ID:EPDNEW_R4806
Type:initiation region
Name:Rere_1
Description:arginine-glutamic acid dipeptide repeats
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4807  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05167,331,023 - 167,331,083EPDNEW
RGD ID:13694282
Promoter ID:EPDNEW_R4807
Type:single initiation site
Name:Rere_2
Description:arginine-glutamic acid dipeptide repeats
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4806  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05167,331,190 - 167,331,250EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:629475 AgrOrtholog
BioCyc Gene G2FUF-39072 BioCyc
Ensembl Genes ENSRNOG00000017940 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024443 ENTREZGENE
  ENSRNOT00000024443.4 UniProtKB/Swiss-Prot
  ENSRNOT00000095232 ENTREZGENE
  ENSRNOT00000103362 ENTREZGENE
Gene3D-CATH 2.30.30.490 UniProtKB/Swiss-Prot
  4.10.1240.50 UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot
InterPro Atrophin-like UniProtKB/Swiss-Prot
  BAH_dom UniProtKB/Swiss-Prot
  BAH_sf UniProtKB/Swiss-Prot
  ELM2_dom UniProtKB/Swiss-Prot
  Homeobox-like_sf UniProtKB/Swiss-Prot
  SANT/Myb UniProtKB/Swiss-Prot
  SANT_dom UniProtKB/Swiss-Prot
  Znf_GATA UniProtKB/Swiss-Prot
KEGG Report rno:116665 UniProtKB/Swiss-Prot
NCBI Gene 116665 ENTREZGENE
PANTHER ARGININE-GLUTAMIC ACID DIPEPTIDE REPEATS PROTEIN UniProtKB/Swiss-Prot
  ATROPHIN-RELATED UniProtKB/Swiss-Prot
Pfam Atrophin-1 UniProtKB/Swiss-Prot
  BAH UniProtKB/Swiss-Prot
  ELM2 UniProtKB/Swiss-Prot
  GATA UniProtKB/Swiss-Prot
PhenoGen Rere PhenoGen
PROSITE BAH UniProtKB/Swiss-Prot
  ELM2 UniProtKB/Swiss-Prot
  SANT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017940 RatGTEx
SMART BAH UniProtKB/Swiss-Prot
  ELM2 UniProtKB/Swiss-Prot
  SANT UniProtKB/Swiss-Prot
  ZnF_GATA UniProtKB/Swiss-Prot
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot
  SSF46689 UniProtKB/Swiss-Prot
UniProt A0A8I6A4P7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A9U2 ENTREZGENE, UniProtKB/TrEMBL
  A6IUD6 ENTREZGENE, UniProtKB/TrEMBL
  A6IUD7_RAT UniProtKB/TrEMBL
  Q62901 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Rere  arginine-glutamic acid dipeptide repeats  Rere  arginine-glutamic acid dipeptide (RE) repeats  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Rere  arginine-glutamic acid dipeptide (RE) repeats      Symbol and Name status set to approved 1299863 APPROVED
2003-04-06 Rere  arginine-glutamic acid dipeptide (RE) repeats      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contain two regions of alternating acidic and basic amino residues similar to those found in atrophin-1  
gene_domains does not contain a glutamine repeat found in atrophin-1 631911
gene_product member of the atrophin-1 gene family