Eaf2 (ELL associated factor 2) - Rat Genome Database

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Gene: Eaf2 (ELL associated factor 2) Rattus norvegicus
Analyze
Symbol: Eaf2
Name: ELL associated factor 2
RGD ID: 628879
Description: Predicted to enable transcription elongation factor activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II; regulation of transcription elongation by RNA polymerase II; and transcription elongation by RNA polymerase II. Predicted to act upstream of or within negative regulation of cell growth and negative regulation of epithelial cell proliferation involved in prostate gland development. Predicted to be located in nucleoplasm. Predicted to be part of transcription elongation factor complex. Orthologous to human EAF2 (ELL associated factor 2); PARTICIPATES IN RNA polymerase II transcription elongation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ELL-associated factor 2; testosterone regulated apoptosis inducer and tumor suppressor; testosterone-regulated apoptosis inducer and tumor suppressor protein; Traits
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81177,465,585 - 77,509,993 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1177,406,020 - 77,509,993 (+)EnsemblGRCr8
mRatBN7.21163,960,200 - 64,004,610 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1163,960,200 - 64,004,610 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1172,772,600 - 72,817,008 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01165,434,824 - 65,479,238 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,469,113 - 64,510,223 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,878,658 - 66,923,092 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,878,658 - 66,923,092 (+)Ensemblrn6Rnor6.0
Rnor_5.01169,969,912 - 70,013,412 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41165,763,410 - 65,809,967 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1163,432,421 - 63,474,673 (+)NCBICelera
RGSC_v3.11165,820,998 - 65,867,556 (+)NCBI
Cytogenetic Map11q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-phenylprop-2-enal  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
Aroclor 1254  (ISO)
belinostat  (ISO)
Benoxacor  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
cisplatin  (ISO)
clothianidin  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dimethyl sulfoxide  (ISO)
dimethylarsinic acid  (ISO)
dorsomorphin  (ISO)
dutasteride  (ISO)
entinostat  (ISO)
finasteride  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gentamycin  (EXP)
L-methionine  (ISO)
linsidomine  (EXP)
lovastatin  (ISO)
manganese(II) chloride  (EXP)
mercury dibromide  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
niclosamide  (ISO)
okadaic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
simvastatin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
testosterone  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The super elongation complex (SEC) family in transcriptional control. Luo Z, etal., Nat Rev Mol Cell Biol. 2012 Sep;13(9):543-7. doi: 10.1038/nrm3417. Epub 2012 Aug 16.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Suppression of prostate tumor growth by U19, a novel testosterone-regulated apoptosis inducer. Xiao W, etal., Cancer Res 2003 Aug 1;63(15):4698-704.
Additional References at PubMed
PMID:12761297   PMID:16114057   PMID:17873910   PMID:22195968  


Genomics

Comparative Map Data
Eaf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81177,465,585 - 77,509,993 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1177,406,020 - 77,509,993 (+)EnsemblGRCr8
mRatBN7.21163,960,200 - 64,004,610 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1163,960,200 - 64,004,610 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1172,772,600 - 72,817,008 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01165,434,824 - 65,479,238 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,469,113 - 64,510,223 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,878,658 - 66,923,092 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,878,658 - 66,923,092 (+)Ensemblrn6Rnor6.0
Rnor_5.01169,969,912 - 70,013,412 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41165,763,410 - 65,809,967 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1163,432,421 - 63,474,673 (+)NCBICelera
RGSC_v3.11165,820,998 - 65,867,556 (+)NCBI
Cytogenetic Map11q21NCBI
EAF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383121,835,209 - 121,886,526 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3121,835,183 - 121,886,526 (+)Ensemblhg38GRCh38
GRCh373121,554,056 - 121,605,373 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,036,724 - 123,088,063 (+)NCBIBuild 36Build 36hg18NCBI36
Build 343123,036,723 - 123,088,062NCBI
Celera3119,963,909 - 120,015,222 (+)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3118,928,117 - 118,979,418 (+)NCBIHuRef
CHM1_13121,517,515 - 121,569,414 (+)NCBICHM1_1
T2T-CHM13v2.03124,555,203 - 124,606,495 (+)NCBIT2T-CHM13v2.0
Eaf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391636,613,246 - 36,695,275 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1636,613,246 - 36,695,365 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381636,792,884 - 36,875,068 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1636,792,884 - 36,875,003 (-)Ensemblmm10GRCm38
MGSCv371636,792,970 - 36,874,912 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361636,712,123 - 36,794,065 (-)NCBIMGSCv36mm8
Celera1637,203,320 - 37,285,700 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.05NCBI
Eaf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,172,009 - 21,204,051 (+)Ensembl
ChiLan1.0NW_00495542721,171,900 - 21,204,138 (+)NCBIChiLan1.0ChiLan1.0
EAF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22119,791,502 - 119,842,980 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13119,796,280 - 119,847,758 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03118,936,685 - 118,996,051 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13125,844,338 - 125,895,416 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3125,844,338 - 125,895,416 (+)EnsemblpanPan2panpan1.1
EAF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13325,113,348 - 25,147,064 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3325,112,570 - 25,146,692 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3325,138,640 - 25,172,592 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03325,348,708 - 25,382,453 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3325,348,721 - 25,383,535 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13325,147,046 - 25,180,866 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03325,189,107 - 25,223,100 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03325,747,329 - 25,781,040 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Eaf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602129,264,251 - 129,308,212 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,213,763 - 8,258,201 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,213,794 - 8,257,595 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EAF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13138,648,270 - 138,681,613 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113138,632,541 - 138,681,607 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213148,259,076 - 148,308,649 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EAF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12258,966,640 - 59,025,158 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2258,974,409 - 59,025,143 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041107,296,606 - 107,348,595 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eaf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912112,843 - 168,553 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624912112,793 - 168,553 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Eaf2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1421,654,312 - 21,694,514 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Eaf2
580 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:192
Count of miRNA genes:147
Interacting mature miRNAs:164
Transcripts:ENSRNOT00000003208
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 3 31 141 76 75 44 89 44 6 273 145 11 116 69 74 31 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000003208   ⟹   ENSRNOP00000003208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1177,465,585 - 77,509,993 (+)Ensembl
mRatBN7.2 Ensembl1163,960,200 - 64,004,610 (+)Ensembl
Rnor_6.0 Ensembl1166,878,658 - 66,923,092 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000141098   ⟹   ENSRNOP00000105762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1177,406,020 - 77,509,993 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000150404   ⟹   ENSRNOP00000101081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1177,464,579 - 77,509,993 (+)Ensembl
RefSeq Acc Id: NM_172047   ⟹   NP_742044
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81177,465,585 - 77,509,993 (+)NCBI
mRatBN7.21163,960,200 - 64,004,610 (+)NCBI
Rnor_6.01166,878,658 - 66,923,092 (+)NCBI
Rnor_5.01169,969,912 - 70,013,412 (+)NCBI
RGSC_v3.41165,763,410 - 65,809,967 (+)RGD
Celera1163,432,421 - 63,474,673 (+)RGD
Sequence:
RefSeq Acc Id: XM_039088053   ⟹   XP_038943981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81177,465,779 - 77,509,988 (+)NCBI
mRatBN7.21163,960,406 - 64,004,610 (+)NCBI
RefSeq Acc Id: XM_039088054   ⟹   XP_038943982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81177,465,688 - 77,509,988 (+)NCBI
mRatBN7.21163,960,316 - 64,004,610 (+)NCBI
RefSeq Acc Id: XM_063270315   ⟹   XP_063126385
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81177,465,682 - 77,509,988 (+)NCBI
RefSeq Acc Id: NP_742044   ⟸   NM_172047
- UniProtKB: Q811X5 (UniProtKB/Swiss-Prot),   A6IRB1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003208   ⟸   ENSRNOT00000003208
RefSeq Acc Id: XP_038943982   ⟸   XM_039088054
- Peptide Label: isoform X1
- UniProtKB: A6IRB3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038943981   ⟸   XM_039088053
- Peptide Label: isoform X1
- UniProtKB: A6IRB3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126385   ⟸   XM_063270315
- Peptide Label: isoform X1
- UniProtKB: A6IRB3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101081   ⟸   ENSRNOT00000150404
Ensembl Acc Id: ENSRNOP00000105762   ⟸   ENSRNOT00000141098
Protein Domains
Transcription elongation factor Eaf N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q811X5-F1-model_v2 AlphaFold Q811X5 1-262 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628879 AgrOrtholog
BioCyc Gene G2FUF-21241 BioCyc
Ensembl Genes ENSRNOG00000002350 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003208 ENTREZGENE
  ENSRNOT00000003208.6 UniProtKB/Swiss-Prot
InterPro EAF_fam UniProtKB/Swiss-Prot
  Tscrpt_elong_fac_Eaf_N UniProtKB/Swiss-Prot
KEGG Report rno:266787 UniProtKB/Swiss-Prot
NCBI Gene 266787 ENTREZGENE
PANTHER ELL-ASSOCIATED FACTOR 2 UniProtKB/Swiss-Prot
  PTHR15970 UniProtKB/Swiss-Prot
Pfam EAF UniProtKB/Swiss-Prot
PhenoGen Eaf2 PhenoGen
RatGTEx ENSRNOG00000002350 RatGTEx
UniProt A0ABK0L048_RAT UniProtKB/TrEMBL
  A0ABK0L6V3_RAT UniProtKB/TrEMBL
  A6IRB1 ENTREZGENE, UniProtKB/TrEMBL
  A6IRB2_RAT UniProtKB/TrEMBL
  A6IRB3 ENTREZGENE, UniProtKB/TrEMBL
  EAF2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-11-08 Eaf2  ELL associated factor 2  Traits  testosterone regulated apoptosis inducer and tumor suppressor  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2003-02-27 Traits  testosterone regulated apoptosis inducer and tumor suppressor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression shows high expression in prostate, bone marrow, kidney, and lymph nodes 634486
gene_mutations_overexpression overexpression induced apoptosis with new protein synthesis being required for apoptosis induction 634486