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Gene: Tank (TRAF family member-associated NFKB activator) Rattus norvegicus

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Symbol:

Tank

Name:

TRAF family member-associated NFKB activator

RGD ID:

628859

Description:

Predicted to enable several functions, including deubiquitinase activator activity; molecular function inhibitor activity; and ubiquitin protein ligase binding activity. Predicted to contribute to cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; negative regulation of signal transduction; and positive regulation of protein deubiquitination. Predicted to act upstream of or within positive regulation of canonical NF-kappaB signal transduction and positive regulation of type I interferon production. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Orthologous to human TANK (TRAF family member associated NFKB activator); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 17beta-estradiol; 3-methylcholanthrene; ammonium chloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

TRAF family member-associated Nf-kappa B activator; TRAF family member-associated NF-kappa-B activator; TRAF interacting protein TANK

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	66,522,834 - 66,598,864 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	66,537,175 - 66,598,864 (+)	Ensembl				GRCr8
mRatBN7.2	3	46,114,230 - 46,190,270 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	46,114,274 - 46,190,264 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	49,452,587 - 49,528,949 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	58,036,094 - 58,112,454 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	55,824,243 - 55,901,927 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	47,439,007 - 47,515,706 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	47,439,076 - 47,515,700 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	54,111,767 - 54,188,472 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	43,396,247 - 43,475,491 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	45,783,047 - 45,858,966 (+)	NCBI		Celera
RGSC_v3.1	3	43,329,797 - 43,371,197 (+)	NCBI
Cytogenetic Map	3	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Breast Neoplasms (ISO)

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-methylcholanthrene (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

4-hydroxyphenyl retinamide (ISO)

5-fluorouracil (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (EXP)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bortezomib (ISO)

Bufotalin (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

coumarin (ISO)

crocidolite asbestos (ISO)

diarsenic trioxide (EXP)

Dibutyl phosphate (ISO)

diclofenac (ISO)

dicrotophos (ISO)

diepoxybutane (ISO)

diethylstilbestrol (EXP)

doxorubicin (ISO)

endosulfan (EXP)

epichlorohydrin (ISO)

ethanol (EXP,ISO)

ethyl methanesulfonate (ISO)

fluoranthene (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

isoflurane (EXP)

lipopolysaccharide (ISO)

methyl methanesulfonate (ISO)

N-acetyl-L-cysteine (ISO)

oxaliplatin (EXP)

p-menthan-3-ol (ISO)

paracetamol (ISO)

phenobarbital (EXP)

silicon dioxide (ISO)

simvastatin (ISO)

sodium arsenite (ISO)

succimer (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

Tributyltin oxide (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

usnic acid (ISO)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to interleukin-1 (IEA,ISO)

cellular response to ionizing radiation (IEA,ISO)

cellular response to tumor necrosis factor (IEA,ISO)

DNA damage response (IEA,ISO)

negative regulation of canonical NF-kappaB signal transduction (IEA,ISO)

negative regulation of tumor necrosis factor-mediated signaling pathway (ISO)

positive regulation of protein deubiquitination (IEA,ISO)

positive regulation of type I interferon production (IEA,ISO)

positive regulation of ubiquitin-specific protease activity (ISO)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (IEA,ISO)

nucleolus (IEA,ISO)

protein-containing complex (IEA,ISO)

Molecular Function

cysteine-type deubiquitinase activity (IEA,ISO)

deubiquitinase activator activity (IEA,ISO)

identical protein binding (IEA,ISO)

metal ion binding (IEA)

molecular adaptor activity (IEA,ISO)

molecular function inhibitor activity (ISO)

protein binding (ISO)

ubiquitin protein ligase binding (IEA,ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases.	Chariot A, etal., J Biol Chem 2002 Oct 4;277(40):37029-36. Epub 2002 Jul 19.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8710854	PMID:11279055	PMID:12477932	PMID:15882800	PMID:25861989

Genomics

Comparative Map Data

Tank
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	66,522,834 - 66,598,864 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	66,537,175 - 66,598,864 (+)	Ensembl				GRCr8
mRatBN7.2	3	46,114,230 - 46,190,270 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	46,114,274 - 46,190,264 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	49,452,587 - 49,528,949 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	58,036,094 - 58,112,454 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	55,824,243 - 55,901,927 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	47,439,007 - 47,515,706 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	47,439,076 - 47,515,700 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	54,111,767 - 54,188,472 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	43,396,247 - 43,475,491 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	45,783,047 - 45,858,966 (+)	NCBI		Celera
RGSC_v3.1	3	43,329,797 - 43,371,197 (+)	NCBI
Cytogenetic Map	3	q21	NCBI

TANK
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	161,136,963 - 161,236,230 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	161,136,908 - 161,236,230 (+)	Ensembl			hg38	GRCh38
GRCh37	2	161,993,474 - 162,092,741 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	161,701,712 - 161,800,928 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	161,818,972 - 161,886,997	NCBI
Celera	2	155,605,253 - 155,704,471 (+)	NCBI		Celera
Cytogenetic Map	2	q24.2	NCBI
HuRef	2	153,878,179 - 153,977,180 (+)	NCBI		HuRef
CHM1_1	2	161,999,604 - 162,098,821 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	161,595,211 - 161,694,538 (+)	NCBI		T2T-CHM13v2.0

Tank
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	61,408,901 - 61,484,515 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	61,408,929 - 61,484,515 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	61,578,557 - 61,654,171 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	61,578,585 - 61,654,171 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	61,416,643 - 61,492,228 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	61,379,425 - 61,454,950 (+)	NCBI		MGSCv36	mm8
Celera	2	63,280,293 - 63,355,826 (+)	NCBI		Celera
Cytogenetic Map	2	C1.3	NCBI
cM Map	2	35.56	NCBI

Tank
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955449	12,470,085 - 12,561,370 (-)	Ensembl
ChiLan1.0	NW_004955449	12,470,203 - 12,561,364 (-)	NCBI	ChiLan1.0	ChiLan1.0

TANK
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	63,847,693 - 63,923,533 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	63,839,226 - 63,938,505 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	48,426,036 - 48,525,265 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	165,797,247 - 165,896,438 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	165,820,833 - 165,896,438 (+)	Ensembl			panPan2	panpan1.1

TANK
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	6,732,507 - 6,826,762 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	6,750,265 - 6,826,486 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	6,869,111 - 6,962,895 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	6,855,580 - 6,949,743 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	6,855,616 - 6,949,726 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	6,871,470 - 6,966,109 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	6,916,601 - 7,010,763 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	7,023,842 - 7,118,152 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tank
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	123,862,875 - 123,952,061 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	17,665,593 - 17,742,422 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	17,665,604 - 17,754,845 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TANK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	67,952,173 - 68,048,963 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	67,970,972 - 68,048,681 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	75,433,203 - 75,529,766 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TANK
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	46,527,795 - 46,632,133 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	46,556,614 - 46,632,186 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	152,907,321 - 153,010,811 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tank
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624732	4,220,963 - 4,300,861 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624732	4,221,294 - 4,325,199 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tank
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	39,232,504 - 39,293,517 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tank
652 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	285
Count of miRNA genes:	195
Interacting mature miRNAs:	221
Transcripts:	ENSRNOT00000011794
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	28625339	67641995	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	35403199	97383526	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	58601291	153936591	Rat
631832	Sach1	Saccharin preference QTL 1	2.7	0.02	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	3	47904172	92904172	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
9590286	Uminl1	Urine mineral level QTL 1	3.5	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	3	48657744	93657744	Rat
10450816	Scl75	Serum cholesterol level QTL 75	4.4	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	58601291	71157804	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	37796919	82796919	Rat
2313093	Bmd77	Bone mineral density QTL 77	2.2	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	3	47904172	70710963	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	38708931	67641995	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	38708931	67641995	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	38708931	67641995	Rat
61356	Bp37	Blood pressure QTL 37	3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	51092561	96092561	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	36721849	110333156	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	38708931	67641995	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	38708931	67641995	Rat
2313101	Bmd76	Bone mineral density QTL 76	3.6	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	3	47904172	70710963	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	38708931	67641995	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	38708931	67641995	Rat
8694196	Abfw2	Abdominal fat weight QTL 2	16.58	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	48657744	93657744	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	36101403	81101403	Rat
10450852	Stl33	Serum triglyceride level QTL 33	3.4	0.05	blood LDL triglyceride amount (VT:0010699)	blood lipoprotein triglyceride level (CMO:0002685)	3	58601291	71157804	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
4889975	Bmd81	Bone mineral density QTL 81	4.3		tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	3	59119402	70710963	Rat
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	51490129	111359995	Rat
634317	Bw117	Body weight QTL 117	3.58		abdominal fat pad mass (VT:1000711)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	59863663	73704481	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	59863663	87321459	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	53651826	98651826	Rat
2303593	Gluco46	Glucose level QTL 46	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	48876619	93876619	Rat
1354590	Despr11	Despair related QTL 11		0.000031	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	3	48876619	93876619	Rat
2313079	Bss73	Bone structure and strength QTL 73	1.5		tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	3	47904172	70710963	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	59863663	87321459	Rat
631647	Bp122	Blood pressure QTL 122	6.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	51092561	96092561	Rat
2313076	Bss74	Bone structure and strength QTL 74	2	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	3	47904172	70710963	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	36425116	81425116	Rat
10450813	Scl74	Serum cholesterol level QTL 74	5.8	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	58601291	71157804	Rat
2302276	Bw82	Body weight QTL 82	4.32		body mass (VT:0001259)	body weight (CMO:0000012)	3	59863663	83358329	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	58925062	103925062	Rat
9590136	Scort3	Serum corticosterone level QTL 3	23.37	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	48657744	93657744	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	50766145	95766145	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	50766145	95766145	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	42158111	124558371	Rat
2325840	Bp345	Blood pressure QTL 345		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	38708931	83708931	Rat
8552950	Pigfal12	Plasma insulin-like growth factor 1 level QTL 12	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	48657744	93657744	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	37363734	82363734	Rat
8694386	Bw159	Body weight QTL 159	4.52	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	3	48657744	93657744	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	42158111	124558371	Rat
2313049	Bss72	Bone structure and strength QTL 72	2.6	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	3	47904172	70710963	Rat

Markers in Region

D3Chm10

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	46,174,894 - 46,175,108 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	47,500,330 - 47,500,543	NCBI	Rnor6.0
Rnor_5.0	3	54,173,096 - 54,173,309	UniSTS	Rnor5.0
RGSC_v3.4	3	43,460,143 - 43,460,357	RGD	RGSC3.4
RGSC_v3.4	3	43,460,144 - 43,460,357	UniSTS	RGSC3.4
Celera	3	45,843,591 - 45,843,804	UniSTS
Cytogenetic Map	3	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001164073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_145788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064568	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_591517	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ422211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC129086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EV776506	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000011794 ⟹ ENSRNOP00000011794

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	66,537,243 - 66,598,864 (+)	Ensembl
mRatBN7.2 Ensembl	3	46,128,652 - 46,190,264 (+)	Ensembl
Rnor_6.0 Ensembl	3	47,439,076 - 47,515,700 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081682 ⟹ ENSRNOP00000071679

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	66,537,175 - 66,598,861 (+)	Ensembl
mRatBN7.2 Ensembl	3	46,128,652 - 46,190,264 (+)	Ensembl
Rnor_6.0 Ensembl	3	47,453,821 - 47,515,700 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116799 ⟹ ENSRNOP00000092979

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	66,537,259 - 66,598,802 (+)	Ensembl
mRatBN7.2 Ensembl	3	46,114,274 - 46,190,193 (+)	Ensembl

RefSeq Acc Id:

NM_001164073 ⟹ NP_001157545

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,522,837 - 66,598,864 (+)	NCBI
mRatBN7.2	3	46,114,230 - 46,190,270 (+)	NCBI
Rnor_6.0	3	47,439,076 - 47,515,706 (+)	NCBI
Rnor_5.0	3	54,111,767 - 54,188,472 (+)	NCBI
RGSC_v3.4	3	43,396,247 - 43,475,491 (+)	RGD
Celera	3	45,783,047 - 45,858,966 (+)	RGD

Sequence:

show sequence

GTGCAAACGGTTTCCAGAATGTGTCCGTGCCTGTCTTTAAAGAGACACAGTCAGTGAAGGAAAA
CTTGTCACCTGGAGAAGAGAGCTGGCATTCGTACCATCCTTTATAGTGATGCTACAGGACAAAG
AGGAATGGATAAAAACATTGGCGAGCAACTCAATAGAGCATATGAAGCCTTCCGACAGGCATGC
ATGGATAGAGATTCAGCAGTAAGAGAGCTGCAGCAGAAGACTGAGAACTATGAACAAAGAATAC
GCGAGCAACAGGAACAGCTGTCATTTCAACAAACTCTCATTGACAGGCTAAAGTCACAGCTACG
TCTTGTGGATTCTAGTCGAGATAACACTTGTGACTATGTACCTTTGCTTGAAGACAGTGACAGA
AGGAAGAATAATTTGACCCTTGATGAACCACATGATAAAGTGAAACTAGGAACACTGAGAGATA
AGCAATCAAAGGTGAGAAGACAAGAAGTTTCTTCTGGAAAAGAGACCTCAAAGGATCTCAGCAT
CCCTTTGCATCATGAAAGGGATAATATAGAGAAGACTTTCTGGGACCTTAAAGAAGAATTTCAT
AGGATATGCTTACTAGCAAAAGCACAGAAAGACCACTTAAGCAAACTTAATATACCAGATATTG
CAACTGACACACAGTGTTCTGTGCCTATACAGTGTACCGATAAAACAGAAAAACAAGAAGCGCT
GTTTAAGCCCCAGGCTAAAGATGATATAAATAGAGGTATGTCGTGCGTCACATCTGTCACACCA
AGAGGACTGGGCCGGGATGAGGAAGATACCTCTTTTGAATCGCTTTCTAAATTCAATGTCAAGT
TTCCGCCTGTGGACAGTGACTCTACTTTTCTACATAGCACTCCAGAGACCCCGAGCATCCTTGC
TCCCTCCACACCTGAGGCAGTGTGCCAGGACAAGTTTAATGTGGAAGTCAGAGACAGCCCAGGA
AACTTGGTTAAAACAGAAGAAACTTTATTTGAAATTCAGGGAATTAACCCCATAACTTCAGCTA
TACAAAACCTTAAAACAACTGACAAAACAAAACCCTCAAATCTTAGAGCTCCGTGTTTGCCAGC
TGGAGACCATAATGTGTTCTATGTAAATACGTTCCCACTTCAAGACCCGCCTGACGCACCTTTT
CCCTCACTGGATTCCCCAGGAAAGGCTGTCCGAGGACCACAGCAGCCCCTTTGGAAGCCTTTTC
CTAACCAAGACACTGACTTAGTGGTACCAAGTGGTTCAGACTCAGTACTCCTTAAACCTCAAGT
GTGTGAGTTCTGTCAAGAGCTTTTCCCACCATCCCTTACATCCAGAGGGGATTTCCTCCGGCAT
CTTAATACACACTTTAATGGAGAGACTTAAATCACATTTGAAAACAGACATATCATGTTCTCTG
TGATGGTTTTGAGTTTGTAATGCTAGAGAATGCTTGCTTGTAAGCTAAATTTAAGGTTGTGTAT
AAAAGAAATTCATTGTCACAGCTATTTGAATTTTTCTCTAAAGTTGTTACTCTATCTTTTAAGA
GATCATTTTGTATATAAAAAACTATAATTCATTATATTATATTATTCATGTTTATACTATAATT
TCCAGATTTCAAAATTACGCATGTGACCTACAGAGTTATGTAATCATAATTTATGTTCTAAATG
GCTAAGTTTATTGTTTGACTCTCACGAAATCTATTAAATTTGGTTATATCAAATGTTTATAGGG
TATTCAAATTTCATTTGAATTTTTAATTATACTACAGGTAATATTCCTTTAAAATATGTTTGTA
ACTTACAGATAATAGCAGACAATATGATCAAAGTAAATATCAAATCAATCATTAGTTGCCCAGT
GAAAATTATTTAAACATTTTAGATCATTTTTTAAATAATACACATGGTTTTAATTTTTACTATG
TGTATAAAATGCATGATTGAGTGATTATTATTAAATATTAAAAGTTCCTTATGTCATGATTATT
GAAAGTGTTCTTTGTTTCTGAGGTAAATAAATCACATTTGGGGAGGGTTCATAAAAAAAAAAAA
AAAAAAAAAAAAAAAAGG

hide sequence

RefSeq Acc Id:

NM_145788 ⟹ NP_665731

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,537,243 - 66,598,864 (+)	NCBI
mRatBN7.2	3	46,128,636 - 46,190,270 (+)	NCBI
Rnor_6.0	3	47,453,882 - 47,515,706 (+)	NCBI
Rnor_5.0	3	54,111,767 - 54,188,472 (+)	NCBI
RGSC_v3.4	3	43,396,247 - 43,475,491 (+)	RGD
Celera	3	45,797,400 - 45,858,966 (+)	NCBI

Sequence:

show sequence

GAACTGGAACGGAAAGCAACTTCCGGCTGCAGTCGTTCTGCCGGGCACCGGCGACCTGTAGCGT
GAGAGCGCGCGGCGGAAACCCTCAACTAGCTGGCATTCGTACCATCCTTTATAGTGATGCTACA
GGACAAAGAGGAATGGATAAAAACATTGGCGAGCAACTCAATAGAGCATATGAAGCCTTCCGAC
AGGCATGCATGGATAGAGATTCAGCAGTAAGAGAGCTGCAGCAGAAGCAGACTGAGAACTATGA
ACAAAGAATACGCGAGCAACAGGAACAGCTGTCATTTCAACAAACTCTCATTGACAGGCTAAAG
TCACAGCTACGTCTTGTGGATTCTAGTCGAGATAACACTTGTGACTATGTACCTTTGCTTGAAG
ACAGTGACAGAAGGAAGAATAATTTGACCCTTGATGAACCACATGATAAAGTGAAACTAGGAAC
ACTGAGAGATAAGCAATCAAAGGTGAGAAGACAAGAAGTTTCTTCTGGAAAAGAGACCTCAAAG
GATCTCAGCATCCCTTTGCATCATGAAAGGGATAATATAGAGAAGACTTTCTGGGACCTTAAAG
AAGAATTTCATAGGATATGCTTACTAGCAAAAGCACAGAAAGACCACTTAAGCAAACTTAATAT
ACCAGATATTGCAACTGACACACAGTGTTCTGTGCCTATACAGTGTACCGATAAAACAGAAAAA
CAAGAAGCGCTGTTTAAGCCCCAGGCTAAAGATGATATAAATAGAGGTATGTCGTGCGTCACAT
CTGTCACACCAAGAGGACTGGGCCGGGATGAGGAAGATACCTCTTTTGAATCGCTTTCTAAATT
CAATGTCAAGTTTCCGCCTGTGGACAGTGACTCTACTTTTCTACATAGCACTCCAGAGACCCCG
AGCATCCTTGCTCCCTCCACACCTGAGGCAGTGTGCCAGGACAAGTTTAATGTGGAAGTCAGAG
ACAGCCCAGGAAACTTGGTTAAAACAGAAGAAACTTTATTTGAAATTCAGGGAATTAACCCCAT
AACTTCAGCTATACAAAACCTTAAAACAACTGACAAAACAAAACCCTCAAATCTTAGAGCTCCG
TGTTTGCCAGCTGGAGACCATAATGTGTTCTATGTAAATACGTTCCCACTTCAAGACCCGCCTG
ACGCACCTTTTCCCTCACTGGATTCCCCAGGAAAGGCTGTCCGAGGACCACAGCAGCCCCTTTG
GAAGCCTTTTCCTAACCAAGACACTGACTTAGTGGTACCAAGTGGTTCAGACTCAGTACTCCTT
AAACCTCAAGTGTGTGAGTTCTGTCAAGAGCTTTTCCCACCATCCCTTACATCCAGAGGGGATT
TCCTCCGGCATCTTAATACACACTTTAATGGAGAGACTTAAATCACATTTGAAAACAGACATAT
CATGTTCTCTGTGATGGTTTTGAGTTTGTAATGCTAGAGAATGCTTGCTTGTAAGCTAAATTTA
AGGTTGTGTATAAAAGAAATTCATTGTCACAGCTATTTGAATTTTTCTCTAAAGTTGTTACTCT
ATCTTTTAAGAGATCATTTTGTATATAAAAAACTATAATTCATTATATTATATTATTCATGTTT
ATACTATAATTTCCAGATTTCAAAATTACGCATGTGACCTACAGAGTTATGTAATCATAATTTA
TGTTCTAAATGGCTAAGTTTATTGTTTGACTCTCACGAAATCTATTAAATTTGGTTATATCAAA
TGTTTATAGGGTATTCAAATTTCATTTGAATTTTTAATTATACTACAGGTAATATTCCTTTAAA
ATATGTTTGTAACTTACAGATAATAGCAGACAATATGATCAAAGTAAATATCAAATCAATCATT
AGTTGCCCAGTGAAAATTATTTAAACATTTTAGATCATTTTTTAAATAATACACATGGTTTTAA
TTTTTACTATGTGTATAAAATGCATGATTGAGTGATTATTATTAAATATTAAAAGTTCCTTATG
TCATGATTATTGAAAGTGTTCTTTGTTTCTGAGGTAAATAAATCACATTTGGGGAGGGTTCATA
AAAAAAAAAAAAAAAAAAAAAAAAAAAGG

hide sequence

RefSeq Acc Id:

XM_006234273 ⟹ XP_006234335

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,522,834 - 66,598,806 (+)	NCBI
mRatBN7.2	3	46,114,253 - 46,190,270 (+)	NCBI
Rnor_6.0	3	47,439,007 - 47,515,706 (+)	NCBI
Rnor_5.0	3	54,111,767 - 54,188,472 (+)	NCBI

Sequence:

show sequence

GTGGAAGTCCCCAGTTCCTTCCACACAAGGGAGAGCTCAGGACAGTTTGGGCAGCATCTGGTAG
AGCCTGTGCAAACGGTTTCCAGAATGTGTCCGTGCCTGTCTTTAAAGAGACACAGTCAGTGAAG
GAAAACTTGTCACCTGGAGAAGAGAGCTGGCATTCGTACCATCCTTTATAGTGATGCTACAGGA
CAAAGAGGAATGGATAAAAACATTGGCGAGCAACTCAATAGAGCATATGAAGCCTTCCGACAGG
CATGCATGGATAGAGATTCAGCAGTAAGAGAGCTGCAGCAGAAGCAGACTGAGAACTATGAACA
AAGAATACGCGAGCAACAGGAACAGCTGTCATTTCAACAAACTCTCATTGACAGGCTAAAGTCA
CAGCTACGTCTTGTGGATTCTAGTCGAGATAACACTTGTGACTATGTACCTTTGCTTGAAGACA
GTGACAGAAGGAAGAATAATTTGACCCTTGATGAACCACATGATAAAGTGAAACTAGGAACACT
GAGAGATAAGCAATCAAAGGTGAGAAGACAAGAAGTTTCTTCTGGAAAAGAGACCTCAAAGGAT
CTGAGCATCCCTTTGCATCATGAAAGGGATAATATAGAGAAGACTTTCTGGGACCTTAAAGAAG
AATTTCATAGGATATGCTTACTAGCAAAAGCACAGAAAGACCACTTAAGCAAACTTAATATACC
AGATATTGCAACTGACACACAGTGTTCTGTGCCTATACAGTGTACCGATAAAACAGAAAAACAA
GAAGCGCTGTTTAAGCCCCAGGCTAAAGATGATATAAATAGAGGTATGTCGTGCGTCACATCTG
TCACACCAAGAGGACTGGGCCGGGATGAGGAAGATACCTCTTTTGAATCGCTTTCTAAATTCAA
TGTCAAGTTTCCGCCTGTGGACAGTGACTCTACTTTTCTACATAGCACTCCAGAGACCCCGAGC
ATCCTTGCTCCCTCCACACCTGAGGCAGTGTGCCAGGACAAGTTTAATGTGGAAGTCAGAGACA
GCCCAGGAAACTTGGTTAAAACAGAAGAAACTTTATTTGAAATTCAGGGAATTAACCCCATAAC
TTCAGCTATACAAAACCTTAAAACAACTGACAAAACAAAACCCTCAAATCTTAGAGCTCCGTGT
TTGCCAGCTGGAGACCATAATGTGTTCTATGTAAATACGTTCCCACTTCAAGACCCGCCTGACG
CACCTTTTCCCTCACTGGATTCCCCAGGAAAGGCTGTCCGAGGACCACAGCAGCCCCTTTGGAA
GCCTTTTCCTAACCAAGACACTGACTTAGTGGTACCAAGTGGTTCAGACTCAGTACTCCTTAAA
CCTCAAGTGTGTGAGTTCTGTCAAGAGCTTTTCCCACCATCCCTTACATCCAGAGGGGATTTCC
TCCGGCATCTTAATACACACTTTAATGGAGAGACTTAAATCACATTTGAAAACAGACATATCAT
GTTCTCTGTGATGGTTTTGAGTTTGTAATGCTAGAGAATGCTTGCTTGTAAGCTAAATTTAAGG
TTGTGTATAAAAGAAATTCATTGTCACAGCTATTTGAATTTTTCTCTAAAGTTGTTACTCTATC
TTTTAAGAGATCATTTTGTATATAAAAAACTATAATTCATTATATTATATTATTCATGTTTATA
CTATAATTTCCAGATTTCAAAATTACGCATGTGACCTACAGAGTTATGTAATCATAATTTATGT
TCTAAATGGCTAAGTTTATTGTTTGACTCTCACGAAATCTATTAAATTTGGTTATATCAAATGT
TTATAGGGTATTCAAATTTCATTTGAATTTTTAATTATACTACAGGTAATATTCCTTTAAAATA
TGTTTGTAACTTACAGATAATAGCAGACAATATGATCAAAGTAAATATCAAATCAATCATTAGT
TGCCCAGTGAAAATTATTTAAACATTTTAGATCATTTTTTAAATAATACACATGGTTTTAATTT
TTACTATGTGTATAAAATGCATGATTGAGTGATTATTATTAAATATTAAAAGTTCCTTATGTCA
TGATTATTGAAAGTGTTCTTTGTTTCTGAGGTAAATAAATCACATTTGGGGAGGGTTCATAAAA

hide sequence

RefSeq Acc Id:

XM_006234274 ⟹ XP_006234336

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,537,193 - 66,598,806 (+)	NCBI
mRatBN7.2	3	46,128,589 - 46,190,270 (+)	NCBI
Rnor_6.0	3	47,453,831 - 47,515,706 (+)	NCBI
Rnor_5.0	3	54,111,767 - 54,188,472 (+)	NCBI

Sequence:

show sequence

TGAGGATGGAAGGTGAAACGTTAATGACTCAGAGCGCAGTCGCTGCCCTCTGAACTGGAACGGA
AAGCAACTTCCGGCTGCAGTCGTTCTGCCGGGCACCGGCGACCTGTAGCGTGAGAGCGCGCGGC
GGAAACCCTCAACTAGCTGGCATTCGTACCATCCTTTATAGTGATGCTACAGGACAAAGAGGAA
TGGATAAAAACATTGGCGAGCAACTCAATAGAGCATATGAAGCCTTCCGACAGGCATGCATGGA
TAGAGATTCAGCAGTAAGAGAGCTGCAGCAGAAGACTGAGAACTATGAACAAAGAATACGCGAG
CAACAGGAACAGCTGTCATTTCAACAAACTCTCATTGACAGGCTAAAGTCACAGCTACGTCTTG
TGGATTCTAGTCGAGATAACACTTGTGACTATGTACCTTTGCTTGAAGACAGTGACAGAAGGAA
GAATAATTTGACCCTTGATGAACCACATGATAAAGTGAAACTAGGAACACTGAGAGATAAGCAA
TCAAAGGTGAGAAGACAAGAAGTTTCTTCTGGAAAAGAGACCTCAAAGGATCTGAGCATCCCTT
TGCATCATGAAAGGGATAATATAGAGAAGACTTTCTGGGACCTTAAAGAAGAATTTCATAGGAT
ATGCTTACTAGCAAAAGCACAGAAAGACCACTTAAGCAAACTTAATATACCAGATATTGCAACT
GACACACAGTGTTCTGTGCCTATACAGTGTACCGATAAAACAGAAAAACAAGAAGCGCTGTTTA
AGCCCCAGGCTAAAGATGATATAAATAGAGGTATGTCGTGCGTCACATCTGTCACACCAAGAGG
ACTGGGCCGGGATGAGGAAGATACCTCTTTTGAATCGCTTTCTAAATTCAATGTCAAGTTTCCG
CCTGTGGACAGTGACTCTACTTTTCTACATAGCACTCCAGAGACCCCGAGCATCCTTGCTCCCT
CCACACCTGAGGCAGTGTGCCAGGACAAGTTTAATGTGGAAGTCAGAGACAGCCCAGGAAACTT
GGTTAAAACAGAAGAAACTTTATTTGAAATTCAGGGAATTAACCCCATAACTTCAGCTATACAA
AACCTTAAAACAACTGACAAAACAAAACCCTCAAATCTTAGAGCTCCGTGTTTGCCAGCTGGAG
ACCATAATGTGTTCTATGTAAATACGTTCCCACTTCAAGACCCGCCTGACGCACCTTTTCCCTC
ACTGGATTCCCCAGGAAAGGCTGTCCGAGGACCACAGCAGCCCCTTTGGAAGCCTTTTCCTAAC
CAAGACACTGACTTAGTGGTACCAAGTGGTTCAGACTCAGTACTCCTTAAACCTCAAGTGTGTG
AGTTCTGTCAAGAGCTTTTCCCACCATCCCTTACATCCAGAGGGGATTTCCTCCGGCATCTTAA
TACACACTTTAATGGAGAGACTTAAATCACATTTGAAAACAGACATATCATGTTCTCTGTGATG
GTTTTGAGTTTGTAATGCTAGAGAATGCTTGCTTGTAAGCTAAATTTAAGGTTGTGTATAAAAG
AAATTCATTGTCACAGCTATTTGAATTTTTCTCTAAAGTTGTTACTCTATCTTTTAAGAGATCA
TTTTGTATATAAAAAACTATAATTCATTATATTATATTATTCATGTTTATACTATAATTTCCAG
ATTTCAAAATTACGCATGTGACCTACAGAGTTATGTAATCATAATTTATGTTCTAAATGGCTAA
GTTTATTGTTTGACTCTCACGAAATCTATTAAATTTGGTTATATCAAATGTTTATAGGGTATTC
AAATTTCATTTGAATTTTTAATTATACTACAGGTAATATTCCTTTAAAATATGTTTGTAACTTA
CAGATAATAGCAGACAATATGATCAAAGTAAATATCAAATCAATCATTAGTTGCCCAGTGAAAA
TTATTTAAACATTTTAGATCATTTTTTAAATAATACACATGGTTTTAATTTTTACTATGTGTAT
AAAATGCATGATTGAGTGATTATTATTAAATATTAAAAGTTCCTTATGTCATGATTATTGAAAG
TGTTCTTTGTTTCTGAGGTAAATAAATCACATTTGGGGAGGGTTCATAAAA

hide sequence

RefSeq Acc Id:

XM_039104349 ⟹ XP_038960277

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,584,120 - 66,598,806 (+)	NCBI
mRatBN7.2	3	46,175,527 - 46,190,270 (+)	NCBI

RefSeq Acc Id:

XM_039104353 ⟹ XP_038960281

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,537,192 - 66,598,806 (+)	NCBI
mRatBN7.2	3	46,128,589 - 46,190,270 (+)	NCBI

RefSeq Acc Id:

XM_039104354 ⟹ XP_038960282

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,537,265 - 66,598,806 (+)	NCBI
mRatBN7.2	3	46,128,589 - 46,190,270 (+)	NCBI

RefSeq Acc Id:

XM_039104355 ⟹ XP_038960283

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,537,192 - 66,598,806 (+)	NCBI
mRatBN7.2	3	46,128,589 - 46,190,270 (+)	NCBI

RefSeq Acc Id:

XM_039104356 ⟹ XP_038960284

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,537,192 - 66,598,806 (+)	NCBI
mRatBN7.2	3	46,128,589 - 46,190,270 (+)	NCBI

RefSeq Acc Id:

XM_039104358 ⟹ XP_038960286

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,537,192 - 66,575,187 (+)	NCBI
mRatBN7.2	3	46,128,589 - 46,166,591 (+)	NCBI

RefSeq Acc Id:

XM_063283148 ⟹ XP_063139218

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,573,417 - 66,598,806 (+)	NCBI

RefSeq Acc Id:

XR_010064568

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	66,537,289 - 66,589,082 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001157545	(Get FASTA)	NCBI Sequence Viewer
	NP_665731	(Get FASTA)	NCBI Sequence Viewer
	XP_006234335	(Get FASTA)	NCBI Sequence Viewer
	XP_006234336	(Get FASTA)	NCBI Sequence Viewer
	XP_038960277	(Get FASTA)	NCBI Sequence Viewer
	XP_038960281	(Get FASTA)	NCBI Sequence Viewer
	XP_038960282	(Get FASTA)	NCBI Sequence Viewer
	XP_038960283	(Get FASTA)	NCBI Sequence Viewer
	XP_038960284	(Get FASTA)	NCBI Sequence Viewer
	XP_038960286	(Get FASTA)	NCBI Sequence Viewer
	XP_063139218	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88854	(Get FASTA)	NCBI Sequence Viewer
	AAI29087	(Get FASTA)	NCBI Sequence Viewer
	CAD19561	(Get FASTA)	NCBI Sequence Viewer
	EDL78994	(Get FASTA)	NCBI Sequence Viewer
	EDL78997	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011794
	ENSRNOP00000011794.7
	ENSRNOP00000071679
	ENSRNOP00000071679.3
	ENSRNOP00000092979.2

RefSeq Acc Id:	NP_665731 ⟸ NM_145788
- Peptide Label:	isoform 1
- UniProtKB:	Q8VDA2 (UniProtKB/TrEMBL), A0A0G2K130 (UniProtKB/TrEMBL), A6HLU4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDKNIGEQLNRAYEAFRQACMDRDSAVRELQQKQTENYEQRIREQQEQLSFQQTLIDRLKSQLR LVDSSRDNTCDYVPLLEDSDRRKNNLTLDEPHDKVKLGTLRDKQSKVRRQEVSSGKETSKDLSI PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDTQCSVPIQCTDKTEKQEAL FKPQAKDDINRGMSCVTSVTPRGLGRDEEDTSFESLSKFNVKFPPVDSDSTFLHSTPETPSILA PSTPEAVCQDKFNVEVRDSPGNLVKTEETLFEIQGINPITSAIQNLKTTDKTKPSNLRAPCLPA GDHNVFYVNTFPLQDPPDAPFPSLDSPGKAVRGPQQPLWKPFPNQDTDLVVPSGSDSVLLKPQV CEFCQELFPPSLTSRGDFLRHLNTHFNGET hide sequence

RefSeq Acc Id:	NP_001157545 ⟸ NM_001164073
- Peptide Label:	isoform 2
- UniProtKB:	A0A8J8YHZ3 (UniProtKB/TrEMBL), Q8VDA2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDKNIGEQLNRAYEAFRQACMDRDSAVRELQQKTENYEQRIREQQEQLSFQQTLIDRLKSQLRL VDSSRDNTCDYVPLLEDSDRRKNNLTLDEPHDKVKLGTLRDKQSKVRRQEVSSGKETSKDLSIP LHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDTQCSVPIQCTDKTEKQEALF KPQAKDDINRGMSCVTSVTPRGLGRDEEDTSFESLSKFNVKFPPVDSDSTFLHSTPETPSILAP STPEAVCQDKFNVEVRDSPGNLVKTEETLFEIQGINPITSAIQNLKTTDKTKPSNLRAPCLPAG DHNVFYVNTFPLQDPPDAPFPSLDSPGKAVRGPQQPLWKPFPNQDTDLVVPSGSDSVLLKPQVC EFCQELFPPSLTSRGDFLRHLNTHFNGET hide sequence

RefSeq Acc Id:	XP_006234335 ⟸ XM_006234273
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K130 (UniProtKB/TrEMBL), A6HLU4 (UniProtKB/TrEMBL), Q8VDA2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDKNIGEQLNRAYEAFRQACMDRDSAVRELQQKQTENYEQRIREQQEQLSFQQTLIDRLKSQLR LVDSSRDNTCDYVPLLEDSDRRKNNLTLDEPHDKVKLGTLRDKQSKVRRQEVSSGKETSKDLSI PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDTQCSVPIQCTDKTEKQEAL FKPQAKDDINRGMSCVTSVTPRGLGRDEEDTSFESLSKFNVKFPPVDSDSTFLHSTPETPSILA PSTPEAVCQDKFNVEVRDSPGNLVKTEETLFEIQGINPITSAIQNLKTTDKTKPSNLRAPCLPA GDHNVFYVNTFPLQDPPDAPFPSLDSPGKAVRGPQQPLWKPFPNQDTDLVVPSGSDSVLLKPQV CEFCQELFPPSLTSRGDFLRHLNTHFNGET hide sequence

RefSeq Acc Id:	XP_006234336 ⟸ XM_006234274
- Peptide Label:	isoform X2
- UniProtKB:	A0A8J8YHZ3 (UniProtKB/TrEMBL), Q8VDA2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDKNIGEQLNRAYEAFRQACMDRDSAVRELQQKTENYEQRIREQQEQLSFQQTLIDRLKSQLRL VDSSRDNTCDYVPLLEDSDRRKNNLTLDEPHDKVKLGTLRDKQSKVRRQEVSSGKETSKDLSIP LHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDTQCSVPIQCTDKTEKQEALF KPQAKDDINRGMSCVTSVTPRGLGRDEEDTSFESLSKFNVKFPPVDSDSTFLHSTPETPSILAP STPEAVCQDKFNVEVRDSPGNLVKTEETLFEIQGINPITSAIQNLKTTDKTKPSNLRAPCLPAG DHNVFYVNTFPLQDPPDAPFPSLDSPGKAVRGPQQPLWKPFPNQDTDLVVPSGSDSVLLKPQVC EFCQELFPPSLTSRGDFLRHLNTHFNGET hide sequence

Ensembl Acc Id:

ENSRNOP00000011794 ⟸ ENSRNOT00000011794

Ensembl Acc Id:

ENSRNOP00000071679 ⟸ ENSRNOT00000081682

RefSeq Acc Id:	XP_038960281 ⟸ XM_039104353
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038960283 ⟸ XM_039104355
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038960282 ⟸ XM_039104354
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_038960284 ⟸ XM_039104356
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038960286 ⟸ XM_039104358
- Peptide Label:	isoform X8
- UniProtKB:	A6HLU5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038960277 ⟸ XM_039104349
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000092979 ⟸ ENSRNOT00000116799

RefSeq Acc Id:	XP_063139218 ⟸ XM_063283148
- Peptide Label:	isoform X4

Protein Domains

UBZ1-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M101-F1-model_v2	AlphaFold	F1M101	1-413	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692096

Promoter ID:

EPDNEW_R2620

Type:

initiation region

Name:

Tank_2

Description:

TRAF family member-associated NFKB activator

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R2621

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	47,439,029 - 47,439,089	EPDNEW

RGD ID:

13692097

Promoter ID:

EPDNEW_R2621

Type:

initiation region

Name:

Tank_1

Description:

TRAF family member-associated NFKB activator

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R2620

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	47,453,910 - 47,453,970	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628859	AgrOrtholog
BioCyc Gene	G2FUF-49601	BioCyc
Ensembl Genes	ENSRNOG00000008859	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000011794	ENTREZGENE
	ENSRNOT00000011794.8	UniProtKB/TrEMBL
	ENSRNOT00000081682	ENTREZGENE
	ENSRNOT00000081682.3	UniProtKB/TrEMBL
	ENSRNOT00000116799.2	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7317281	IMAGE-MGC_LOAD
	IMAGE:7365827	IMAGE-MGC_LOAD
InterPro	CALCOCO1/2_Zn_UBZ1	UniProtKB/TrEMBL
	TANK	UniProtKB/TrEMBL
	TBD	UniProtKB/TrEMBL
KEGG Report	rno:252961	UniProtKB/TrEMBL
MGC_CLONE	MGC:105308	IMAGE-MGC_LOAD
	MGC:156587	IMAGE-MGC_LOAD
NCBI Gene	252961	ENTREZGENE
PANTHER	PTHR15249	UniProtKB/TrEMBL
	TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR	UniProtKB/TrEMBL
Pfam	TBD	UniProtKB/TrEMBL
PhenoGen	Tank	PhenoGen
PROSITE	ZF_UBZ1	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000008859	RatGTEx
UniProt	A0A0G2K130	ENTREZGENE
	A0A8I6AIS2_RAT	UniProtKB/TrEMBL
	A0A8J8YHZ3	ENTREZGENE, UniProtKB/TrEMBL
	A6HLU4	ENTREZGENE, UniProtKB/TrEMBL
	A6HLU5	ENTREZGENE, UniProtKB/TrEMBL
	F1M101_RAT	UniProtKB/TrEMBL
	Q5HZX1_RAT	UniProtKB/TrEMBL
	Q8VDA2	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A0G2K130	UniProtKB/TrEMBL
	A1L1J0	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-10-23	Tank	TRAF family member-associated NFKB activator	Tank	TRAF family member-associated Nf-kappa B activator	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-08	Tank	TRAF family member-associated Nf-kappa B activator			Symbol and Name status set to approved	1299863	APPROVED
2003-02-27	Tank	TRAF family member-associated Nf-kappa B activator			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)