Tor1aip1 (torsin 1A interacting protein 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Tor1aip1 (torsin 1A interacting protein 1) Rattus norvegicus
Analyze
Symbol: Tor1aip1
Name: torsin 1A interacting protein 1
RGD ID: 628851
Description: Enables lamin binding activity. Predicted to be involved in nuclear membrane organization; positive regulation of ATP-dependent activity; and protein localization to nucleus. Predicted to act upstream of or within protein localization to nuclear envelope. Located in nuclear envelope. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2Y. Orthologous to human TOR1AIP1 (torsin 1A interacting protein 1); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: lamina-associated polypeptide 1B; lamina-associated polypeptide 1C; Lap1b; Lap1c; MGC93149; torsin A interacting protein 1; torsin-1A-interacting protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81370,746,941 - 70,776,382 (-)NCBIGRCr8
mRatBN7.21368,196,681 - 68,226,121 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1368,196,681 - 68,225,862 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1370,776,432 - 70,805,603 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01372,097,134 - 72,126,168 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01369,358,610 - 69,387,653 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01373,670,649 - 73,704,668 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1373,670,141 - 73,704,678 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01378,593,998 - 78,629,999 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41371,042,848 - 71,072,766 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11371,057,068 - 71,086,822 (-)NCBI
Celera1368,060,269 - 68,088,483 (-)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tor1aip1Rat1q24 Deletion Syndrome  ISOTOR1AIP1 (Homo sapiens)8554872ClinVar Annotator: match by term: 1q24q25 microdeletion syndromeClinVarPMID:21548129 more ...
Tor1aip1Ratautosomal recessive chronic granulomatous disease 2  ISOTOR1AIP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Granulomatous disease more ...ClinVarPMID:28492532
Tor1aip1Ratautosomal recessive limb-girdle muscular dystrophy type 2Y  ISOTOR1AIP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16199547 more ...
Tor1aip1Ratcentronuclear myopathy  ISOTOR1AIP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Centronuclear myopathyClinVarPMID:25741868 and PMID:33405017
Tor1aip1Ratgastrointestinal stromal tumor  ISOTOR1AIP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
Tor1aip1Ratgenetic disease  ISOTOR1AIP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Tor1aip1Ratparathyroid carcinoma  ISOTOR1AIP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tor1aip1Ratautosomal recessive limb-girdle muscular dystrophy type 2Y  ISOTOR1AIP1 (Homo sapiens)7240710 OMIM 

1 to 20 of 80 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tor1aip1Rat(+)-catechin multiple interactionsISOTOR1AIP1 (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of TOR1AIP1 mRNACTDPMID:24763279
Tor1aip1Rat1,2-dimethylhydrazine multiple interactionsISOTor1aip1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TOR1AIP1 mRNACTDPMID:22206623
Tor1aip1Rat1,2-dimethylhydrazine affects expressionISOTor1aip1 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of TOR1AIP1 mRNACTDPMID:22206623
Tor1aip1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOTor1aip1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of TOR1AIP1 mRNACTDPMID:21570461
Tor1aip1Rat3,4-methylenedioxymethamphetamine decreases expressionISOTor1aip1 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TOR1AIP1 mRNACTDPMID:26251327
Tor1aip1Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOTOR1AIP1 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TOR1AIP1 mRNACTDPMID:28628672
Tor1aip1Rat4,4'-sulfonyldiphenol affects expressionISOTor1aip1 (Mus musculus)6480464bisphenol S affects the expression of TOR1AIP1 mRNACTDPMID:39298647
Tor1aip1Rat4,4'-sulfonyldiphenol increases expressionISOTOR1AIP1 (Homo sapiens)6480464bisphenol S results in increased expression of TOR1AIP1 proteinCTDPMID:34186270
Tor1aip1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of TOR1AIP1 mRNACTDPMID:30047161
Tor1aip1Ratacrolein multiple interactionsISOTOR1AIP1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TOR1AIP1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TOR1AIP1 mRNACTDPMID:32699268
Tor1aip1Ratactinomycin D multiple interactionsISOTOR1AIP1 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of TOR1AIP1 proteinCTDPMID:38460933
Tor1aip1Rataflatoxin B1 increases methylationISOTOR1AIP1 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of TOR1AIP1 intronCTDPMID:30157460
Tor1aip1Ratall-trans-retinoic acid increases expressionISOTOR1AIP1 (Homo sapiens)6480464Tretinoin results in increased expression of TOR1AIP1 mRNACTDPMID:33167477
Tor1aip1Ratalpha-pinene multiple interactionsISOTOR1AIP1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TOR1AIP1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TOR1AIP1 mRNACTDPMID:32699268
Tor1aip1Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of TOR1AIP1 mRNACTDPMID:30047161
Tor1aip1Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of TOR1AIP1 mRNACTDPMID:16483693
Tor1aip1Rataristolochic acid A decreases expressionISOTOR1AIP1 (Homo sapiens)6480464aristolochic acid I results in decreased expression of TOR1AIP1 mRNACTDPMID:33212167
Tor1aip1Ratarsenite(3-) multiple interactionsISOTOR1AIP1 (Homo sapiens)6480464arsenite inhibits the reaction [G3BP1 protein binds to TOR1AIP1 mRNA]CTDPMID:32406909
Tor1aip1Ratbis(2-ethylhexyl) phthalate multiple interactionsISOTor1aip1 (Mus musculus)6480464PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of TOR1AIP1 mRNA]CTDPMID:19850644
Tor1aip1Ratbis(2-ethylhexyl) phthalate increases expressionISOTor1aip1 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of TOR1AIP1 mRNACTDPMID:19850644

1 to 20 of 80 rows

Biological Process

  

Cellular Component
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tor1aip1Ratendomembrane system located_inIEAARBA:ARBA000289531600115GO_REF:0000117UniProtGO_REF:0000117
Tor1aip1Ratintracellular membrane-bounded organelle located_inIEAARBA:ARBA000290851600115GO_REF:0000117UniProtGO_REF:0000117
Tor1aip1Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Tor1aip1Ratnuclear envelope located_inISOTOR1AIP1 (Homo sapiens) and UniProtKB:Q5JTV8-41624291 PMID:25461922RGDPMID:25461922
Tor1aip1Ratnuclear envelope  IDA 633106 RGD 
Tor1aip1Ratnuclear envelope located_inIEAUniProtKB:Q921T2 and ensembl:ENSMUSP000000951341600115GO_REF:0000107EnsemblGO_REF:0000107
Tor1aip1Ratnuclear envelope located_inISOTor1aip1 (Mus musculus)1624291 PMID:15767459 and PMID:20457914RGDPMID:15767459 and PMID:20457914
Tor1aip1Ratnuclear inner membrane located_inIEAUniProtKB-SubCell:SL-01791600115GO_REF:0000044UniProtGO_REF:0000044
Tor1aip1Ratnuclear membrane located_inISOTOR1AIP1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Tor1aip1Ratnuclear membrane located_inIEAUniProtKB:Q5JTV8 and ensembl:ENSP000004766871600115GO_REF:0000107EnsemblGO_REF:0000107
Tor1aip1Ratnuclear membrane is_active_inIBAPANTHER:PTN000428698 and UniProtKB:Q5JTV81600115GO_REF:0000033GO_CentralGO_REF:0000033
Tor1aip1Ratnucleoplasm located_inISOTOR1AIP1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Tor1aip1Ratnucleoplasm located_inIEAUniProtKB:Q5JTV8 and ensembl:ENSP000004766871600115GO_REF:0000107EnsemblGO_REF:0000107
Tor1aip1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Tor1aip1Ratnucleus located_inIEAUniProtKB:Q5JTV8 and ensembl:ENSP000004766871600115GO_REF:0000107EnsemblGO_REF:0000107
Tor1aip1Ratnucleus located_inISOTOR1AIP1 (Homo sapiens) and UniProtKB:Q5JTV8-41624291 PMID:25461922RGDPMID:25461922
Tor1aip1Ratnucleus located_inISSUniProtKB:Q5JTV81600115GO_REF:0000024UniProtGO_REF:0000024
Tor1aip1Ratnucleus located_inISOTOR1AIP1 (Homo sapiens)1624291 PMID:24275647RGDPMID:24275647
1 to 18 of 18 rows

Molecular Function
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tor1aip1RatATPase activator activity enablesISSUniProtKB:Q5JTV81600115GO_REF:0000024UniProtGO_REF:0000024
Tor1aip1RatATPase activator activity enablesIEAUniProtKB:Q5JTV8 and ensembl:ENSP000004766871600115GO_REF:0000107EnsemblGO_REF:0000107
Tor1aip1RatATPase activator activity enablesIEAInterPro:IPR008662 and InterPro:IPR0467531600115GO_REF:0000002InterProGO_REF:0000002
Tor1aip1RatATPase activator activity enablesISOTOR1AIP1 (Homo sapiens)1624291 PMID:23569223RGDPMID:23569223
Tor1aip1RatATPase binding enablesISOTOR1AIP1 (Homo sapiens)1624291UniProtKB:O14656 and PMID:23569223RGDPMID:23569223
Tor1aip1RatATPase binding enablesIEAUniProtKB:Q5JTV8 and ensembl:ENSP000004766871600115GO_REF:0000107EnsemblGO_REF:0000107
Tor1aip1Ratcytoskeletal protein binding enablesISOTOR1AIP1 (Homo sapiens)1624291UniProtKB:P08670 and PMID:16361107RGDPMID:16361107
Tor1aip1Ratcytoskeletal protein binding enablesIEAUniProtKB:Q5JTV8 and ensembl:ENSP000004766871600115GO_REF:0000107EnsemblGO_REF:0000107
Tor1aip1Ratlamin binding  IDA 633106 RGD 
Tor1aip1Ratprotein binding enablesIPIUniProtKB:P6213814697725PMID:24116158IntAct 
Tor1aip1Ratprotein binding enablesISOTor1aip1 (Mus musculus)1624291PR:Q8R1J9 more ...RGDPMID:15767459 and PMID:20457914
Tor1aip1Ratprotein binding enablesISOTOR1AIP1 (Homo sapiens) and UniProtKB:Q5JTV8-31624291UniProtKB:P36873-1 and PMID:24116158RGDPMID:24116158
Tor1aip1Ratprotein binding enablesISOTOR1AIP1 (Homo sapiens)1624291UniProtKB:O14656 more ...RGDPMID:21044950 more ...
Tor1aip1Ratprotein binding enablesIPIUniProtKB:P6308814697725PMID:24116158IntAct 
Tor1aip1Ratprotein binding enablesIPIUniProtKB:Q9R1932306466PMID:17592128UniProt 
1 to 15 of 15 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. cDNA cloning and characterization of lamina-associated polypeptide 1C (LAP1C), an integral protein of the inner nuclear membrane. Martin L, etal., J Biol Chem 1995 Apr 14;270(15):8822-8.
3. Evolution of Na,K-ATPase beta m-subunit into a coregulator of transcription in placental mammals. Pestov NB, etal., Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11215-20. Epub 2007 Jun 25.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. The nuclear envelope protein, LAP1B, is a novel protein phosphatase 1 substrate. Santos M, etal., PLoS One. 2013 Oct 7;8(10):e76788. doi: 10.1371/journal.pone.0076788. eCollection 2013.
PMID:12477932   PMID:15489334   PMID:15767459   PMID:16128803   PMID:16361107   PMID:20457914   PMID:23569223   PMID:24275647  



Tor1aip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81370,746,941 - 70,776,382 (-)NCBIGRCr8
mRatBN7.21368,196,681 - 68,226,121 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1368,196,681 - 68,225,862 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1370,776,432 - 70,805,603 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01372,097,134 - 72,126,168 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01369,358,610 - 69,387,653 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01373,670,649 - 73,704,668 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1373,670,141 - 73,704,678 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01378,593,998 - 78,629,999 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41371,042,848 - 71,072,766 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11371,057,068 - 71,086,822 (-)NCBI
Celera1368,060,269 - 68,088,483 (-)NCBICelera
Cytogenetic Map13q22NCBI
TOR1AIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381179,882,285 - 179,920,076 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1179,882,042 - 179,920,077 (+)EnsemblGRCh38hg38GRCh38
GRCh371179,851,420 - 179,889,211 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361178,118,043 - 178,155,834 (+)NCBINCBI36Build 36hg18NCBI36
Celera1152,959,025 - 152,996,742 (+)NCBICelera
Cytogenetic Map1q25.2NCBI
HuRef1151,083,015 - 151,120,943 (+)NCBIHuRef
CHM1_11181,274,983 - 181,312,965 (+)NCBICHM1_1
T2T-CHM13v2.01179,238,027 - 179,275,744 (+)NCBIT2T-CHM13v2.0
Tor1aip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,880,328 - 155,912,226 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,880,345 - 155,912,226 (-)EnsemblGRCm39 Ensembl
GRCm381156,004,599 - 156,036,480 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1156,004,599 - 156,036,480 (-)EnsemblGRCm38mm10GRCm38
MGSCv371157,851,729 - 157,883,610 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361157,768,999 - 157,798,513 (-)NCBIMGSCv36mm8
Celera1158,442,340 - 158,474,394 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map167.69NCBI
Tor1aip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540619,122,926 - 19,151,522 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540619,122,906 - 19,152,458 (+)NCBIChiLan1.0ChiLan1.0
TOR1AIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2169,847,349 - 69,886,436 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1169,505,625 - 69,544,043 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01155,362,806 - 155,401,185 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,042,982 - 159,081,408 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,043,072 - 159,081,408 (+)Ensemblpanpan1.1panPan2
TOR1AIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1713,452,808 - 13,501,392 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl713,452,949 - 13,501,307 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha713,031,899 - 13,080,621 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0713,179,822 - 13,228,560 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl713,179,965 - 13,266,838 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1713,091,335 - 13,140,041 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0713,197,272 - 13,245,962 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0713,322,123 - 13,370,847 (+)NCBIUU_Cfam_GSD_1.0
Tor1aip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934491,387,630 - 91,415,014 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364819,232,588 - 9,262,563 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364819,234,379 - 9,261,961 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOR1AIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9121,515,570 - 121,566,796 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19121,515,691 - 121,566,799 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29133,362,871 - 133,391,167 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TOR1AIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12549,454,642 - 49,492,903 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2549,452,289 - 49,491,525 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605550,849,688 - 50,887,405 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tor1aip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624771172,666 - 200,893 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624771172,429 - 202,427 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Tor1aip1
237 total Variants


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
13 68197985 68197986 C T snv PVG/Seac (2019) View more Information


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
13 73671953 73671954 C T snv PVG/Seac (2019) View more Information

Predicted Target Of
Summary Value
Count of predictions:113
Count of miRNA genes:86
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000005280, ENSRNOT00000005296
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 32 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat

1 to 10 of 32 rows
RH129301  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21368,196,722 - 68,196,916 (+)MAPPERmRatBN7.2
Rnor_6.01373,670,691 - 73,670,884NCBIRnor6.0
Rnor_5.01378,595,740 - 78,595,933UniSTSRnor5.0
RGSC_v3.41371,042,890 - 71,043,083UniSTSRGSC3.4
Celera1368,060,311 - 68,060,504UniSTS
RH 3.4 Map81192.4UniSTS
Cytogenetic Map13q21UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000005280   ⟹   ENSRNOP00000005280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1368,196,681 - 68,225,862 (-)Ensembl
Rnor_6.0 Ensembl1373,670,141 - 73,704,678 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000005296   ⟹   ENSRNOP00000005296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1368,197,444 - 68,225,862 (-)Ensembl
Rnor_6.0 Ensembl1373,671,412 - 73,704,480 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098741   ⟹   ENSRNOP00000085745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1368,196,681 - 68,225,862 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107683   ⟹   ENSRNOP00000087328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1368,196,681 - 68,225,862 (-)Ensembl
RefSeq Acc Id: NM_145092   ⟹   NP_659560
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81370,746,941 - 70,776,123 (-)NCBI
mRatBN7.21368,196,681 - 68,225,862 (-)NCBI
Rnor_6.01373,670,649 - 73,704,668 (-)NCBI
Rnor_5.01378,593,998 - 78,629,999 (-)NCBI
RGSC_v3.41371,042,848 - 71,072,766 (-)RGD
Celera1368,060,269 - 68,088,483 (-)RGD
Sequence:
RefSeq Acc Id: XM_006250027   ⟹   XP_006250089
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81370,746,946 - 70,774,560 (-)NCBI
mRatBN7.21368,197,301 - 68,224,299 (-)NCBI
Rnor_6.01373,670,650 - 73,703,162 (-)NCBI
Rnor_5.01378,593,998 - 78,629,999 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250028   ⟹   XP_006250090
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81370,746,946 - 70,775,002 (-)NCBI
mRatBN7.21368,197,301 - 68,224,977 (-)NCBI
Rnor_6.01373,670,650 - 73,703,973 (-)NCBI
Rnor_5.01378,593,998 - 78,629,999 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090334   ⟹   XP_038946262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81370,746,946 - 70,776,382 (-)NCBI
mRatBN7.21368,197,317 - 68,226,121 (-)NCBI
RefSeq Acc Id: NP_659560   ⟸   NM_145092
- UniProtKB: Q62741 (UniProtKB/Swiss-Prot),   Q62754 (UniProtKB/Swiss-Prot),   Q5PQX1 (UniProtKB/Swiss-Prot),   A6ICZ9 (UniProtKB/TrEMBL),   A0A8I6AGC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250090   ⟸   XM_006250028
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006250089   ⟸   XM_006250027
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000005296   ⟸   ENSRNOT00000005296
Ensembl Acc Id: ENSRNOP00000005280   ⟸   ENSRNOT00000005280
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PQX1-F1-model_v2 AlphaFold Q5PQX1 1-583 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13698912
Promoter ID:EPDNEW_R9437
Type:initiation region
Name:Tor1aip1_1
Description:torsin 1A interacting protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01373,704,689 - 73,704,749EPDNEW


1 to 32 of 32 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-17826 BioCyc
Ensembl Genes ENSRNOG00000003946 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005280 ENTREZGENE
  ENSRNOT00000005280.7 UniProtKB/Swiss-Prot
  ENSRNOT00000098741 ENTREZGENE
Gene3D-CATH 3.40.50.12190 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7129718 IMAGE-MGC_LOAD
InterPro Lamina-ass_polypeptide_CLAP1C UniProtKB/Swiss-Prot
  LAP1C-like_C_sf UniProtKB/Swiss-Prot
  TOIP1/2_C UniProtKB/Swiss-Prot
  TOIP1/2_N UniProtKB/Swiss-Prot
KEGG Report rno:246314 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93149 IMAGE-MGC_LOAD
NCBI Gene 246314 ENTREZGENE
PANTHER PTHR18843 UniProtKB/Swiss-Prot
  TORSIN-1A-INTERACTING PROTEIN 1 UniProtKB/Swiss-Prot
Pfam LAP1_N UniProtKB/Swiss-Prot
  LAP1C UniProtKB/Swiss-Prot
PhenoGen Tor1aip1 PhenoGen
RatGTEx ENSRNOG00000003946 RatGTEx
UniProt A0A8I6A2B4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AGC6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q1H0_RAT UniProtKB/TrEMBL
  A6ICZ8_RAT UniProtKB/TrEMBL
  A6ICZ9 ENTREZGENE, UniProtKB/TrEMBL
  A6ID00_RAT UniProtKB/TrEMBL
  Q5PQX1 ENTREZGENE
  Q62741 ENTREZGENE
  Q62754 ENTREZGENE
  TOIP1_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q62741 UniProtKB/Swiss-Prot
  Q62754 UniProtKB/Swiss-Prot
1 to 32 of 32 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Tor1aip1  torsin 1A interacting protein 1  Tor1aip1  torsin A interacting protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Tor1aip1  torsin A interacting protein 1  Lap1b  lamina-associated polypeptide 1B  Symbol and Name updated 1299863 APPROVED
2005-01-20 Lap1b  lamina-associated polypeptide 1B  Lap1c  lamina-associated polypeptide 1C  Symbol and Name updated 1299863 APPROVED
2003-02-27 Lap1c  lamina-associated polypeptide 1C      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_cellular_localization localized to the inner nuclear membrane 633106
gene_protein 506-amino acid protein 633106