Nr1d2 (nuclear receptor subfamily 1, group D, member 2) - Rat Genome Database

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Gene: Nr1d2 (nuclear receptor subfamily 1, group D, member 2) Rattus norvegicus
Analyze
Symbol: Nr1d2
Name: nuclear receptor subfamily 1, group D, member 2
RGD ID: 628828
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear receptor activity. Predicted to be involved in several processes, including energy homeostasis; regulation of skeletal muscle cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human NR1D2 (nuclear receptor subfamily 1 group D member 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EAR4; HZF-2; nuclear receptor subfamily 1 group D member 2; orphan nuclear receptor HZF-2; orphan receptor; rev-erb-beta; Rev-erb-Beta2; Rev-ErbA-beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8159,955,034 - 9,981,329 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl159,954,906 - 9,981,330 (+)EnsemblGRCr8
mRatBN7.2157,524,257 - 7,550,553 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl157,524,257 - 7,550,553 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx159,669,777 - 9,696,183 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01510,582,568 - 10,608,974 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0158,882,996 - 8,909,403 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0158,730,871 - 8,757,165 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl158,730,871 - 8,757,165 (+)Ensemblrn6Rnor6.0
Rnor_5.01512,792,652 - 12,819,056 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera157,577,813 - 7,604,107 (+)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-phenylbutyric acid  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
avobenzone  (ISO)
azoxystrobin  (EXP)
benzene  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bromuconazole  (EXP)
buspirone  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcium atom  (EXP)
calcium silicate  (ISO)
calcium(0)  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
D-gluconic acid  (EXP)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
deoxycholic acid  (EXP)
deoxynivalenol  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzofuran  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dichloromethane  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
flavonoids  (EXP)
fluoranthene  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glucose  (ISO)
glyphosate  (EXP)
GSK-J4  (ISO)
imidacloprid  (EXP)
L-methionine  (ISO)
leflunomide  (ISO)
manganese(II) chloride  (EXP)
mercury dichloride  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
motexafin gadolinium  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
niclosamide  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propanal  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
SCH-351591  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
styrene  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thiabendazole  (EXP)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
triadimefon  (EXP)
tributylstannane  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
zinc acetate  (ISO)
zinc atom  (EXP)
zinc sulfate  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Identification of a novel member of the nuclear receptor superfamily which is closely related to Rev-ErbA. Enmark E, etal., Biochem Biophys Res Commun 1994 Oct 14;204(1):49-56.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Molecular cloning and brain localization of HZF-2 alpha, a new member of the Rev-erb subfamily of orphan nuclear receptors. Pena-de-Ortiz S and Jamieson GA Jr, J Neurobiol 1997 Mar;32(3):341-58.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7838156   PMID:7838158   PMID:7914660   PMID:8747539   PMID:11058961   PMID:15623503   PMID:17892483   PMID:17996965   PMID:19682428   PMID:21076970   PMID:23221024   PMID:29508494  
PMID:29533925   PMID:29723273   PMID:36077427  


Genomics

Comparative Map Data
Nr1d2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8159,955,034 - 9,981,329 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl159,954,906 - 9,981,330 (+)EnsemblGRCr8
mRatBN7.2157,524,257 - 7,550,553 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl157,524,257 - 7,550,553 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx159,669,777 - 9,696,183 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01510,582,568 - 10,608,974 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0158,882,996 - 8,909,403 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0158,730,871 - 8,757,165 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl158,730,871 - 8,757,165 (+)Ensemblrn6Rnor6.0
Rnor_5.01512,792,652 - 12,819,056 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera157,577,813 - 7,604,107 (+)NCBICelera
Cytogenetic Map15p16NCBI
NR1D2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38323,945,286 - 23,980,617 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl323,945,286 - 23,980,637 (+)Ensemblhg38GRCh38
GRCh37323,986,777 - 24,022,108 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36323,961,810 - 23,996,241 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34323,961,809 - 23,996,240NCBI
Celera323,931,547 - 23,957,664 (+)NCBICelera
Cytogenetic Map3p24.2NCBI
HuRef323,933,388 - 23,968,134 (+)NCBIHuRef
CHM1_1323,938,552 - 23,973,891 (+)NCBICHM1_1
T2T-CHM13v2.0323,950,061 - 23,985,372 (+)NCBIT2T-CHM13v2.0
Nr1d2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39144,230,549 - 4,265,639 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl144,230,569 - 4,265,642 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381418,204,056 - 18,239,106 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1418,204,054 - 18,239,127 (-)Ensemblmm10GRCm38
MGSCv371419,036,570 - 19,071,620 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361416,997,184 - 17,032,113 (-)NCBIMGSCv36mm8
Celera1413,893,071 - 13,928,619 (-)NCBICelera
Cytogenetic Map14A1NCBI
cM Map147.08NCBI
Nr1d2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543015,812,448 - 15,834,412 (+)Ensembl
ChiLan1.0NW_00495543015,812,449 - 15,834,341 (+)NCBIChiLan1.0ChiLan1.0
NR1D2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2223,906,233 - 23,941,262 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1323,910,999 - 23,946,029 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0323,857,317 - 23,892,533 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1324,189,931 - 24,215,831 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl324,185,798 - 24,215,831 (+)EnsemblpanPan2panpan1.1
NR1D2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12319,758,907 - 19,787,725 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2319,762,052 - 19,787,614 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2319,757,060 - 19,785,724 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02320,065,641 - 20,094,314 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2320,065,641 - 20,094,489 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12319,880,835 - 19,909,714 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02319,990,566 - 20,019,259 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02320,099,576 - 20,128,270 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nr1d2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118182,486,589 - 182,508,302 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647315,624,587 - 15,647,451 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647315,624,597 - 15,646,875 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR1D2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1310,756,926 - 10,791,210 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11310,756,954 - 10,791,219 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21312,197,595 - 12,222,718 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NR1D2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11568,632,142 - 68,668,467 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1568,632,197 - 68,665,258 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604141,756,095 - 41,791,606 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nr1d2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11287,265,675 - 87,291,642 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nr1d2
131 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:105
Count of miRNA genes:92
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000071751
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
1300142Bp191Blood pressure QTL 1913.14arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)15115177511Rat

Markers in Region
RH134269  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2157,549,552 - 7,549,771 (+)MAPPERmRatBN7.2
Rnor_6.0158,756,165 - 8,756,383NCBIRnor6.0
Rnor_5.01512,818,053 - 12,818,271UniSTSRnor5.0
Celera157,603,107 - 7,603,325UniSTS
RH 3.4 Map1573.5UniSTS
Cytogenetic Map15p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000071751   ⟹   ENSRNOP00000065585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl159,962,938 - 9,981,330 (+)Ensembl
mRatBN7.2 Ensembl157,532,162 - 7,550,553 (+)Ensembl
Rnor_6.0 Ensembl158,739,589 - 8,754,831 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000081845   ⟹   ENSRNOP00000075553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl159,954,906 - 9,981,330 (+)Ensembl
mRatBN7.2 Ensembl157,524,257 - 7,550,553 (+)Ensembl
Rnor_6.0 Ensembl158,730,871 - 8,757,165 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106171   ⟹   ENSRNOP00000095677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl157,533,772 - 7,550,553 (+)Ensembl
RefSeq Acc Id: NM_147210   ⟹   NP_671743
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8159,955,034 - 9,981,329 (+)NCBI
mRatBN7.2157,524,257 - 7,550,553 (+)NCBI
Rnor_6.0158,730,871 - 8,757,165 (+)NCBI
Rnor_5.01512,792,652 - 12,819,056 (+)NCBI
Celera157,577,813 - 7,604,107 (+)NCBI
Sequence:
RefSeq Acc Id: NP_671743   ⟸   NM_147210
- UniProtKB: Q62756 (UniProtKB/Swiss-Prot),   Q63542 (UniProtKB/Swiss-Prot),   Q63504 (UniProtKB/Swiss-Prot),   A6K037 (UniProtKB/TrEMBL),   A0A0H2UI31 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075553   ⟸   ENSRNOT00000081845
Ensembl Acc Id: ENSRNOP00000065585   ⟸   ENSRNOT00000071751
Ensembl Acc Id: ENSRNOP00000095677   ⟸   ENSRNOT00000106171
Protein Domains
NR LBD   Nuclear receptor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63504-F1-model_v2 AlphaFold Q63504 1-578 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699578
Promoter ID:EPDNEW_R10101
Type:initiation region
Name:Nr1d2_1
Description:nuclear receptor subfamily 1, group D, member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0158,730,913 - 8,730,973EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628828 AgrOrtholog
BioCyc Gene G2FUF-14458 BioCyc
Ensembl Genes ENSRNOG00000046912 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000081845 ENTREZGENE
  ENSRNOT00000081845.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot
  3.30.50.10 UniProtKB/Swiss-Prot
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot
  Nuclear_hormone_rcpt_NR1 UniProtKB/Swiss-Prot
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot
  Znf_NHR/GATA UniProtKB/Swiss-Prot
KEGG Report rno:259241 UniProtKB/Swiss-Prot
NCBI Gene 259241 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/Swiss-Prot
  NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2 UniProtKB/Swiss-Prot
Pfam Hormone_recep UniProtKB/Swiss-Prot
  zf-C4 UniProtKB/Swiss-Prot
PhenoGen Nr1d2 PhenoGen
PRINTS STRDHORMONER UniProtKB/Swiss-Prot
  STROIDFINGER UniProtKB/Swiss-Prot
PROSITE NR_LBD UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000046912 RatGTEx
SMART HOLI UniProtKB/Swiss-Prot
  ZnF_C4 UniProtKB/Swiss-Prot
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot
  SSF48508 UniProtKB/Swiss-Prot
UniProt A0A0H2UI31 ENTREZGENE, UniProtKB/TrEMBL
  A6K037 ENTREZGENE, UniProtKB/TrEMBL
  A6K039_RAT UniProtKB/TrEMBL
  NR1D2_RAT UniProtKB/Swiss-Prot
  Q62756 ENTREZGENE
  Q63504 ENTREZGENE
  Q63542 ENTREZGENE
UniProt Secondary Q62756 UniProtKB/Swiss-Prot
  Q63542 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Nr1d2  nuclear receptor subfamily 1, group D, member 2      Symbol and Name status set to approved 625702 APPROVED
2003-02-27 Nr1d2  nuclear receptor subfamily 1, group D, member 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expression increases during neonatal brain development and remains elevated in the adult brain 729070