Nr1d1 (nuclear receptor subfamily 1, group D, member 1) - Rat Genome Database

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Gene: Nr1d1 (nuclear receptor subfamily 1, group D, member 1) Rattus norvegicus
Analyze
Symbol: Nr1d1
Name: nuclear receptor subfamily 1, group D, member 1
RGD ID: 628827
Description: Enables transcription cis-regulatory region binding activity. Involved in several processes, including photoperiodism; positive regulation of circadian rhythm; and regulation of hepatic stellate cell activation. Located in dendrite and neuronal cell body. Biomarker of hyperthyroidism; hypothyroidism; portal hypertension; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in brain small vessel disease. Orthologous to human NR1D1 (nuclear receptor subfamily 1 group D member 1); INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EAR-1; nuclear receptor subfamily 1 group D member 1; rev-erb alpha; rev-erbA-alpha; REV-ERBAALPHA; V-erbA-related protein 1; V-erbA-related protein EAR-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81084,224,599 - 84,231,812 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1084,224,540 - 84,231,812 (-)EnsemblGRCr8
mRatBN7.21083,728,348 - 83,735,562 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1083,728,318 - 83,735,705 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1088,672,225 - 88,679,439 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01088,170,300 - 88,177,514 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01083,563,001 - 83,570,215 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01086,683,875 - 86,690,815 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1086,683,875 - 86,690,815 (-)Ensemblrn6Rnor6.0
Rnor_5.01086,479,868 - 86,486,808 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41087,541,246 - 87,548,186 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1082,476,555 - 82,483,495 (-)NCBICelera
RGSC_v3.11087,555,629 - 87,560,471 (-)NCBI
Cytogenetic Map10q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (EXP)
1,2-dimethylhydrazine  (ISO)
1,3-dichloropropan-2-ol  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-amino-4,6-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitro-m-cresol  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP)
Alisol A  (EXP)
Alisol B  (EXP)
Alisol C 23-acetate  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid A  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[ghi]perylene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bromuconazole  (EXP)
buta-1,3-diene  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcium silicate  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
CGS-21680  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (EXP,ISO)
chlorpyrifos  (EXP)
chrysene  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cypermethrin  (ISO)
decabromodiphenyl ether  (EXP)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
dichloromethane  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
diethyl maleate  (EXP)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
fluoranthene  (ISO)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glyphosate  (EXP,ISO)
GSK-J4  (ISO)
haloperidol  (EXP)
hexachlorobenzene  (EXP)
hyaluronic acid  (ISO)
hypochlorous acid  (ISO)
ibuprofen  (ISO)
imidacloprid  (EXP)
indole-3-methanol  (EXP)
Jujuboside A  (ISO)
ketamine  (EXP)
ketoconazole  (EXP)
lead(0)  (ISO)
leflunomide  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
luteolin  (ISO)
manganese(II) chloride  (EXP)
metformin  (EXP)
methamphetamine  (ISO)
methotrexate  (ISO)
Moniliformin  (ISO)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (EXP)
naphthalenes  (EXP)
nevirapine  (EXP)
niclosamide  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenformin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
prednisolone  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (EXP)
propiconazole  (ISO)
quercetin  (EXP)
raloxifene  (ISO)
resveratrol  (EXP)
rotenone  (EXP)
SCH-351591  (EXP)
scopolamine  (EXP)
senecionine  (ISO)
sevoflurane  (EXP)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sotorasib  (ISO)
streptozocin  (EXP)
styrene  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
trametinib  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
undecane  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cell differentiation  (IBA,IEA)
cellular response to interleukin-1  (IEA,ISO,ISS)
cellular response to lipopolysaccharide  (IEA,ISO)
cellular response to tumor necrosis factor  (IEA,ISO,ISS)
cholesterol homeostasis  (IEA,ISO,ISS)
circadian regulation of gene expression  (IEA,ISO,ISS)
circadian rhythm  (IEA,IEP,ISO)
circadian temperature homeostasis  (IEA,ISO,ISS)
glycogen biosynthetic process  (IEA,ISO,ISS)
hormone-mediated signaling pathway  (IBA)
intracellular glucose homeostasis  (IEA,ISO,ISS)
intracellular receptor signaling pathway  (IBA)
negative regulation of astrocyte activation  (IEA,ISO,ISS)
negative regulation of canonical NF-kappaB signal transduction  (IEA,ISO,ISS)
negative regulation of cold-induced thermogenesis  (IEA,ISO,ISS)
negative regulation of DNA-templated transcription  (IEA,ISO,ISS)
negative regulation of inflammatory response  (IEA,ISO,ISS)
negative regulation of microglial cell activation  (IEA,ISO,ISS)
negative regulation of neuroinflammatory response  (IEA,ISO,ISS)
negative regulation of toll-like receptor 4 signaling pathway  (IEA,ISO)
negative regulation of transcription by RNA polymerase II  (IBA,IEA,ISO)
photoperiodism  (IEP)
positive regulation of bile acid biosynthetic process  (IEA,ISO,ISS)
positive regulation of circadian rhythm  (IDA)
positive regulation of DNA-templated transcription  (IDA,IEA,ISO)
positive regulation of transcription by RNA polymerase II  (IBA)
proteasomal protein catabolic process  (IEA,ISO,ISS)
protein destabilization  (IEA,ISO,ISS)
regulation of circadian rhythm  (IDA,IEA,ISO)
regulation of circadian sleep/wake cycle  (IEA,ISO,ISS)
regulation of DNA-templated transcription  (IEA,ISO)
regulation of fat cell differentiation  (IEA,ISO,ISS)
regulation of gene expression  (IEA)
regulation of hepatic stellate cell activation  (IDA)
regulation of insulin secretion involved in cellular response to glucose stimulus  (IEA,ISO,ISS)
regulation of lipid metabolic process  (IEA,ISO,ISS)
regulation of primary metabolic process  (IEA)
regulation of type B pancreatic cell proliferation  (IEA,ISO,ISS)
response to leptin  (IBA,IEA,ISO,ISS)
rhythmic process  (IEA)

Cellular Component
chromatin  (IEA,ISO)
cytoplasm  (IEA,ISO,ISS)
dendrite  (IDA,IEA,ISO,ISS)
dendritic spine  (IEA,ISO,ISS)
neuronal cell body  (IDA)
nuclear body  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Rev-erbalpha regulates circadian rhythms and StAR expression in rat granulosa cells as identified by the agonist GSK4112. Chen H, etal., Biochem Biophys Res Commun. 2012 Apr 6;420(2):374-9. doi: 10.1016/j.bbrc.2012.02.164. Epub 2012 Mar 8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The nuclear receptor Rev-erba controls circadian thermogenic plasticity. Gerhart-Hines Z, etal., Nature. 2013 Nov 21;503(7476):410-413. doi: 10.1038/nature12642. Epub 2013 Oct 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. The orphan receptor Rev-ErbA alpha activates transcription via a novel response element. Harding HP and Lazar MA, Mol Cell Biol. 1993 May;13(5):3113-21.
6. [Pulmonary expression of Nr1d1 in rats with ventilation-induced lung injury]. Hu J and Wang C, Nan Fang Yi Ke Da Xue Xue Bao. 2013 Oct;33(10):1544-6.
7. Developmental expression of mRNAs from a rat C-erbA genomic locus. Jannini EA, etal., Biochem Biophys Res Commun. 1992 Apr 30;184(2):739-45.
8. A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit. Lazar MA, etal., Mol Cell Biol 1989 Mar;9(3):1128-36.
9. Novel role of nuclear receptor Rev-erbalpha in hepatic stellate cell activation: potential therapeutic target for liver injury. Li T, etal., Hepatology. 2014 Jun;59(6):2383-96. doi: 10.1002/hep.27049. Epub 2014 Apr 29.
10. The thyroid hormone receptor alpha locus and white matter lesions: a role for the clock gene REV-ERBalpha. Medici M, etal., Thyroid. 2012 Nov;22(11):1181-6. doi: 10.1089/thy.2012.0198. Epub 2012 Oct 19.
11. Ligand modulation of REV-ERBalpha function resets the peripheral circadian clock in a phasic manner. Meng QJ, etal., J Cell Sci. 2008 Nov 1;121(Pt 21):3629-35. doi: 10.1242/jcs.035048.
12. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Rat Rev-erbA alpha, an orphan receptor related to thyroid hormone receptor, binds to specific thyroid hormone response elements. Spanjaard RA, etal., Mol Endocrinol. 1994 Mar;8(3):286-95.
17. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
18. Effect of phase delay lighting rotation schedule on daily expression of per2, bmal1, rev-erbalpha, pparalpha, and pdk4 genes in the heart and liver of Wistar rats. Szantoova K, etal., Mol Cell Biochem. 2011 Feb;348(1-2):53-60. doi: 10.1007/s11010-010-0636-x. Epub 2010 Nov 14.
19. A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbalpha. Valnegri P, etal., Nat Neurosci. 2011 Aug 28;14(10):1293-301. doi: 10.1038/nn.2911.
20. Association of Rev-erbalpha in adipose tissues with Type 2 diabetes mellitus amelioration after gastric bypass surgery in Goto-Kakizaki rats. Zhang R, etal., Am J Physiol Regul Integr Comp Physiol. 2013 Jul 15;305(2):R134-46. doi: 10.1152/ajpregu.00520.2012. Epub 2013 May 1.
Additional References at PubMed
PMID:7838158   PMID:8622974   PMID:12150932   PMID:12821652   PMID:14645221   PMID:15761026   PMID:18006707   PMID:18227153   PMID:18511497   PMID:18565334   PMID:19721697   PMID:19955433  
PMID:20070857   PMID:20159955   PMID:20424134   PMID:21628546   PMID:21952132   PMID:22166979   PMID:23398316   PMID:24030830   PMID:24355794   PMID:24794873   PMID:25588874   PMID:25648833  
PMID:26102301   PMID:26811051   PMID:27686098   PMID:29508494   PMID:29533925   PMID:29653076   PMID:30096135   PMID:30555544   PMID:30792350   PMID:31957097   PMID:36077427   PMID:38279698  
PMID:38324049  


Genomics

Comparative Map Data
Nr1d1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81084,224,599 - 84,231,812 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1084,224,540 - 84,231,812 (-)EnsemblGRCr8
mRatBN7.21083,728,348 - 83,735,562 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1083,728,318 - 83,735,705 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1088,672,225 - 88,679,439 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01088,170,300 - 88,177,514 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01083,563,001 - 83,570,215 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01086,683,875 - 86,690,815 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1086,683,875 - 86,690,815 (-)Ensemblrn6Rnor6.0
Rnor_5.01086,479,868 - 86,486,808 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41087,541,246 - 87,548,186 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1082,476,555 - 82,483,495 (-)NCBICelera
RGSC_v3.11087,555,629 - 87,560,471 (-)NCBI
Cytogenetic Map10q31NCBI
NR1D1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381740,092,793 - 40,100,589 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1740,092,793 - 40,100,589 (-)Ensemblhg38GRCh38
GRCh371738,249,046 - 38,256,842 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,502,567 - 35,510,499 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341735,502,566 - 35,510,499NCBI
Celera1734,909,147 - 34,917,084 (-)NCBICelera
Cytogenetic Map17q21.1NCBI
HuRef1734,042,773 - 34,050,715 (-)NCBIHuRef
CHM1_11738,484,740 - 38,492,682 (-)NCBICHM1_1
T2T-CHM13v2.01740,956,678 - 40,964,476 (-)NCBIT2T-CHM13v2.0
Nr1d1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391198,658,758 - 98,666,233 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1198,658,758 - 98,666,159 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381198,767,932 - 98,775,377 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1198,767,932 - 98,775,333 (-)Ensemblmm10GRCm38
MGSCv371198,629,249 - 98,636,556 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361198,584,022 - 98,590,912 (-)NCBIMGSCv36mm8
Celera11108,422,591 - 108,429,908 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1162.66NCBI
Nr1d1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545114,742,735 - 14,750,999 (-)Ensembl
ChiLan1.0NW_00495545114,743,763 - 14,750,903 (-)NCBIChiLan1.0ChiLan1.0
NR1D1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21924,852,065 - 24,862,137 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11726,748,938 - 26,756,937 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01717,188,390 - 17,196,315 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11717,409,669 - 17,417,600 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1717,409,669 - 17,417,600 (+)EnsemblpanPan2panpan1.1
NR1D1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1922,461,556 - 22,469,243 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl922,461,705 - 22,469,053 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha921,933,902 - 21,941,575 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0923,254,745 - 23,262,432 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl923,254,822 - 23,262,435 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1922,028,188 - 22,035,862 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0922,287,169 - 22,294,857 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0922,411,920 - 22,419,594 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nr1d1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560221,861,286 - 21,868,939 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649015,206,191 - 15,213,867 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649015,206,194 - 15,213,858 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR1D1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1222,263,657 - 22,271,643 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11222,263,549 - 22,274,131 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NR1D1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11666,078,990 - 66,086,927 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1666,079,089 - 66,090,685 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607736,982,347 - 36,990,288 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nr1d1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247953,102,439 - 3,109,497 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247953,102,424 - 3,109,497 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nr1d1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1955,660,965 - 55,668,429 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nr1d1
66 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:187
Count of miRNA genes:98
Interacting mature miRNAs:104
Transcripts:ENSRNOT00000012537, ENSRNOT00000055333
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105107189796071897Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)1067476608107713808Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063719161107713808Rat
631555Bp134Blood pressure QTL 1340.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)108101207791729860Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1058073360103073360Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105429633699451733Rat
4889948Bss91Bone structure and strength QTL 914tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)108306123692869129Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105046480295464802Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1064939013107713808Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076951790107713808Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)1079272424102982300Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1073599825107713808Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
10450495Bp383Blood pressure QTL 3830.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313395464802Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105086028895860288Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1066817119107713808Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107395035396620293Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
724516Uae17Urinary albumin excretion QTL 173.6urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)107870758585720738Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106724133498502431Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106184349698710773Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)107369533997272278Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1065390777107713808Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1081012077101828297Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107304965694495280Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)104949549294495492Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068920187107713808Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)1065307813107713808Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070698731107713808Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105530797293608131Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1061843496100198886Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104994371094943710Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1066108888107555881Rat
2325836Bp346Blood pressure QTL 3460.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313384503487Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1061843496100198886Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104786912992869129Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313395604677Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105060467795604677Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107395035396620293Rat
631537Oia4Oil induced arthritis QTL 4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1076128947107713808Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
RH133144  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21083,729,162 - 83,729,353 (+)MAPPERmRatBN7.2
Rnor_6.01086,684,690 - 86,684,880NCBIRnor6.0
Rnor_5.01086,480,683 - 86,480,873UniSTSRnor5.0
RGSC_v3.41087,542,061 - 87,542,251UniSTSRGSC3.4
Celera1082,477,370 - 82,477,560UniSTS
RH 3.4 Map10858.6UniSTS
Cytogenetic Map10q31UniSTS
AW259572  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21083,729,114 - 83,729,206 (+)MAPPERmRatBN7.2
Rnor_6.01086,684,642 - 86,684,733NCBIRnor6.0
Rnor_5.01086,480,635 - 86,480,726UniSTSRnor5.0
RGSC_v3.41087,542,013 - 87,542,104UniSTSRGSC3.4
Celera1082,477,322 - 82,477,413UniSTS
Cytogenetic Map10q31UniSTS
BF387429  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21083,732,373 - 83,732,559 (+)MAPPERmRatBN7.2
Rnor_6.01086,687,901 - 86,688,086NCBIRnor6.0
Rnor_5.01086,483,894 - 86,484,079UniSTSRnor5.0
RGSC_v3.41087,545,272 - 87,545,457UniSTSRGSC3.4
Celera1082,480,581 - 82,480,766UniSTS
RH 3.4 Map10876.09UniSTS
Cytogenetic Map10q31UniSTS
D17S1644E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21083,729,253 - 83,729,324 (+)MAPPERmRatBN7.2
Rnor_6.01086,684,781 - 86,684,851NCBIRnor6.0
Rnor_5.01086,480,774 - 86,480,844UniSTSRnor5.0
RGSC_v3.41087,542,152 - 87,542,222UniSTSRGSC3.4
Celera1082,477,461 - 82,477,531UniSTS
Cytogenetic Map10q31UniSTS
MARC_5497-5498:996690469:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81084,225,050 - 84,225,790 (+)Marker Load Pipeline
mRatBN7.21083,728,799 - 83,729,539 (+)MAPPERmRatBN7.2
Rnor_6.01086,684,327 - 86,685,066NCBIRnor6.0
Rnor_5.01086,480,320 - 86,481,059UniSTSRnor5.0
RGSC_v3.41087,541,698 - 87,542,437UniSTSRGSC3.4
Celera1082,477,007 - 82,477,746UniSTS
Cytogenetic Map10q31UniSTS
RH125185  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21083,728,377 - 83,728,548 (+)MAPPERmRatBN7.2
Rnor_6.01086,683,905 - 86,684,075NCBIRnor6.0
Rnor_5.01086,479,898 - 86,480,068UniSTSRnor5.0
RGSC_v3.41087,541,276 - 87,541,446UniSTSRGSC3.4
Celera1082,476,585 - 82,476,755UniSTS
Cytogenetic Map10q31UniSTS
NR1D1_2626  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21083,728,163 - 83,728,854 (+)MAPPERmRatBN7.2
Rnor_6.01086,683,691 - 86,684,381NCBIRnor6.0
Rnor_5.01086,479,684 - 86,480,374UniSTSRnor5.0
RGSC_v3.41087,541,062 - 87,541,752UniSTSRGSC3.4
Celera1082,476,371 - 82,477,061UniSTS
Cytogenetic Map10q31UniSTS
THRA_2263  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21083,728,582 - 83,729,339 (+)MAPPERmRatBN7.2
Rnor_6.01086,684,110 - 86,684,866NCBIRnor6.0
Rnor_5.01086,480,103 - 86,480,859UniSTSRnor5.0
RGSC_v3.41087,541,481 - 87,542,237UniSTSRGSC3.4
Celera1082,476,790 - 82,477,546UniSTS
Cytogenetic Map10q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 91 59 6 355 191 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012537   ⟹   ENSRNOP00000012537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1084,224,599 - 84,231,812 (-)Ensembl
mRatBN7.2 Ensembl1083,728,349 - 83,735,705 (-)Ensembl
Rnor_6.0 Ensembl1086,683,875 - 86,690,815 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000055333   ⟹   ENSRNOP00000052200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1084,224,599 - 84,228,753 (-)Ensembl
mRatBN7.2 Ensembl1083,728,348 - 83,732,502 (-)Ensembl
Rnor_6.0 Ensembl1086,683,875 - 86,688,730 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117389   ⟹   ENSRNOP00000080936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1084,224,540 - 84,231,812 (-)Ensembl
mRatBN7.2 Ensembl1083,728,318 - 83,735,705 (-)Ensembl
RefSeq Acc Id: NM_001113422   ⟹   NP_001106893
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81084,224,599 - 84,231,812 (-)NCBI
mRatBN7.21083,728,348 - 83,735,562 (-)NCBI
Rnor_6.01086,683,875 - 86,690,815 (-)NCBI
Rnor_5.01086,479,868 - 86,486,808 (-)NCBI
RGSC_v3.41087,541,246 - 87,548,186 (-)RGD
Celera1082,476,555 - 82,483,495 (-)RGD
Sequence:
RefSeq Acc Id: NM_145775   ⟹   NP_665718
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81084,224,599 - 84,229,454 (-)NCBI
mRatBN7.21083,728,348 - 83,733,204 (-)NCBI
Rnor_6.01086,683,875 - 86,688,730 (-)NCBI
Rnor_5.01086,479,868 - 86,486,808 (-)NCBI
RGSC_v3.41087,541,246 - 87,548,186 (-)RGD
Celera1082,476,555 - 82,481,410 (-)NCBI
Sequence:
RefSeq Acc Id: NP_665718   ⟸   NM_145775
- Peptide Label: isoform 2
- UniProtKB: G3V9L8 (UniProtKB/TrEMBL),   A6HIU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106893   ⟸   NM_001113422
- Peptide Label: isoform 1
- UniProtKB: Q6P6S7 (UniProtKB/Swiss-Prot),   Q63503 (UniProtKB/Swiss-Prot),   G3V770 (UniProtKB/TrEMBL),   A6HIU8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000052200   ⟸   ENSRNOT00000055333
Ensembl Acc Id: ENSRNOP00000012537   ⟸   ENSRNOT00000012537
Ensembl Acc Id: ENSRNOP00000080936   ⟸   ENSRNOT00000117389
Protein Domains
NR LBD   Nuclear receptor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63503-F1-model_v2 AlphaFold Q63503 1-615 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697671
Promoter ID:EPDNEW_R8195
Type:single initiation site
Name:Nr1d1_1
Description:nuclear receptor subfamily 1, group D, member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01086,690,773 - 86,690,833EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628827 AgrOrtholog
BioCyc Gene G2FUF-23344 BioCyc
Ensembl Genes ENSRNOG00000009329 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000012537 ENTREZGENE
  ENSRNOT00000055333 ENTREZGENE
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot
  3.30.50.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5598020 IMAGE-MGC_LOAD
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot
  Nuclear_hormone_rcpt_NR1 UniProtKB/Swiss-Prot
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot
  Znf_NHR/GATA UniProtKB/Swiss-Prot
KEGG Report rno:252917 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72288 IMAGE-MGC_LOAD
NCBI Gene 252917 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/Swiss-Prot
  NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 1 UniProtKB/Swiss-Prot
Pfam Hormone_recep UniProtKB/Swiss-Prot
  zf-C4 UniProtKB/Swiss-Prot
PhenoGen Nr1d1 PhenoGen
PRINTS STRDHORMONER UniProtKB/Swiss-Prot
  STROIDFINGER UniProtKB/Swiss-Prot
PROSITE NR_LBD UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009329 RatGTEx
SMART HOLI UniProtKB/Swiss-Prot
  ZnF_C4 UniProtKB/Swiss-Prot
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot
  SSF48508 UniProtKB/Swiss-Prot
UniProt A0A8I5ZRE2_RAT UniProtKB/TrEMBL
  A6HIU8 ENTREZGENE, UniProtKB/TrEMBL
  A6HIU9 ENTREZGENE, UniProtKB/TrEMBL
  G3V770 ENTREZGENE, UniProtKB/TrEMBL
  G3V9L8 ENTREZGENE, UniProtKB/TrEMBL
  NR1D1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P6S7 ENTREZGENE
UniProt Secondary Q6P6S7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Nr1d1  nuclear receptor subfamily 1, group D, member 1      Symbol and Name status set to approved 625702 APPROVED
2003-02-27 Nr1d1  nuclear receptor subfamily 1, group D, member 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression highly expressed in skeletal muscle and brown fat 728950
gene_other gene overlaps with r-erbA alpha-2 gene 728950