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Gene: Cops2 (COP9 signalosome subunit 2) Rattus norvegicus

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Symbol:

Cops2

Name:

COP9 signalosome subunit 2

RGD ID:

628791

Description:

Predicted to enable transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II and neuron differentiation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of COP9 signalosome. Orthologous to human COPS2 (COP9 signalosome subunit 2); INTERACTS WITH 6-propyl-2-thiouracil; aconitine; allethrin.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

alien homolog; COP9 (constitutive photomorphogenic) homolog, subunit 2; COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana); COP9 constitutive photomorphogenic homolog subunit 2; COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis); COP9 signalosome complex subunit 2; CSN2; JAB1-containing signalosome subunit 2; SGN2; signalosome subunit 2; thyroid receptor-interacting protein 15; TR-interacting protein 15; TRIP-15; Trip15; tyroid receptor interacting protein 15

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	COPS2 (COP9 signalosome subunit 2)	HGNC	Ensembl, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cops2 (COP9 signalosome subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cops2 (COP9 signalosome subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	COPS2 (COP9 signalosome subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	COPS2 (COP9 signalosome subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cops2 (COP9 signalosome subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	COPS2 (COP9 signalosome subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	COPS2 (COP9 signalosome subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cops2 (COP9 signalosome subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cops2 (COP9 signalosome subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Cops2 (COP9 signalosome subunit 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	COPS2 (COP9 signalosome subunit 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cops2 (COP9 signalosome subunit 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cops2 (COP9 signalosome subunit 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	alien	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	csn-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	csn-2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cops2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	133,537,729 - 133,563,493 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	133,537,732 - 133,563,369 (-)	Ensembl				GRCr8
mRatBN7.2	3	113,084,174 - 113,110,090 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	113,084,176 - 113,109,947 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	116,951,304 - 116,976,245 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	125,546,826 - 125,571,767 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	123,207,197 - 123,232,138 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	118,109,394 - 118,137,125 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	118,109,406 - 118,137,191 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	124,631,885 - 124,661,562 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	113,142,049 - 113,166,263 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	111,940,307 - 111,964,790 (-)	NCBI		Celera
RGSC_v3.1	3	113,047,621 - 113,071,836 (-)	NCBI
Cytogenetic Map	3	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

endometriosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aconitine (EXP)

aflatoxin M1 (ISO)

allethrin (EXP)

antirheumatic drug (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

Brodifacoum (EXP)

Butylparaben (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

ciguatoxin CTX1B (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

cyhalothrin (EXP)

cypermethrin (EXP)

dibutyl phthalate (ISO)

dicrotophos (ISO)

dioxygen (ISO)

disodium selenite (ISO)

enzacamene (EXP)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenvalerate (EXP)

flutamide (EXP)

folic acid (ISO)

GSK-J4 (ISO)

indirubin (ISO)

ivermectin (ISO)

kojic acid (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

Mesaconitine (EXP)

methimazole (EXP)

methoxychlor (EXP)

methylmercury chloride (ISO)

ozone (ISO)

paracetamol (EXP)

pentachlorophenol (ISO)

phenobarbital (ISO)

pyrethrins (EXP)

quercetin (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

taurine (ISO)

tetrahydropalmatine (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell population proliferation (ISO)

inner cell mass cell proliferation (ISO)

negative regulation of DNA-templated transcription (ISO)

negative regulation of transcription by RNA polymerase II (IDA)

neuron differentiation (IDA)

protein deneddylation (IBA,IEA,ISO)

protein phosphorylation (ISO)

skeletal muscle cell differentiation (ISO)

Cellular Component

COP9 signalosome (IBA,IEA,ISO)

cytoplasm (IEA,ISO)

intercellular bridge (IEA,ISO)

nucleus (IEA,ISO)

Molecular Function

protein binding (IPI,ISO)

transcription corepressor activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Implication of Trip15/CSN2 in early stage of neuronal differentiation of P19 embryonal carcinoma cells.	Akiyama H, etal., Brain Res Dev Brain Res 2003 Jan 10;140(1):45-56.
2.	The role of transcriptional corepressor Nif3l1 in early stage of neural differentiation via cooperation with Trip15/CSN2.	Akiyama H, etal., J Biol Chem. 2003 Mar 21;278(12):10752-62. Epub 2003 Jan 8.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9535219	PMID:9707402	PMID:12477932	PMID:12606288	PMID:12972599	PMID:15062575	PMID:15489334	PMID:18850735	PMID:19141280	PMID:22147266	PMID:22871113	PMID:28131823
PMID:32408015

Genomics

Comparative Map Data

Cops2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	133,537,729 - 133,563,493 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	133,537,732 - 133,563,369 (-)	Ensembl				GRCr8
mRatBN7.2	3	113,084,174 - 113,110,090 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	113,084,176 - 113,109,947 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	116,951,304 - 116,976,245 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	125,546,826 - 125,571,767 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	123,207,197 - 123,232,138 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	118,109,394 - 118,137,125 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	118,109,406 - 118,137,191 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	124,631,885 - 124,661,562 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	113,142,049 - 113,166,263 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	111,940,307 - 111,964,790 (-)	NCBI		Celera
RGSC_v3.1	3	113,047,621 - 113,071,836 (-)	NCBI
Cytogenetic Map	3	q36	NCBI

COPS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	49,122,727 - 49,155,599 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	49,106,068 - 49,155,661 (-)	Ensembl			hg38	GRCh38
GRCh37	15	49,414,924 - 49,447,796 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	47,206,834 - 47,235,077 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	15	47,206,833 - 47,235,073	NCBI
Celera	15	26,311,045 - 26,341,430 (-)	NCBI		Celera
Cytogenetic Map	15	q21.1	NCBI
HuRef	15	26,249,544 - 26,279,925 (-)	NCBI		HuRef
CHM1_1	15	49,535,767 - 49,566,147 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	46,930,938 - 46,963,811 (-)	NCBI		T2T-CHM13v2.0

Cops2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	125,672,222 - 125,701,002 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	125,672,224 - 125,701,059 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	125,830,302 - 125,859,082 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	125,830,304 - 125,859,139 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	125,656,040 - 125,684,754 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	125,521,745 - 125,550,459 (-)	NCBI		MGSCv36	mm8
Celera	2	127,074,518 - 127,103,040 (-)	NCBI		Celera
Cytogenetic Map	2	F1	NCBI
cM Map	2	61.76	NCBI

Cops2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	4,859,972 - 4,891,575 (+)	Ensembl
ChiLan1.0	NW_004955409	4,859,971 - 4,888,487 (+)	NCBI	ChiLan1.0	ChiLan1.0

COPS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	38,365,682 - 38,395,287 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	42,548,974 - 42,579,154 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	28,073,237 - 28,103,615 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	46,396,077 - 46,426,396 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	46,396,077 - 46,426,396 (-)	Ensembl			panPan2	panpan1.1

COPS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	15,332,411 - 15,365,528 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	15,334,096 - 15,365,443 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	15,256,236 - 15,289,340 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	15,468,434 - 15,501,493 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	15,467,895 - 15,501,386 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	15,391,942 - 15,424,988 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	15,513,371 - 15,546,462 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	15,619,268 - 15,652,382 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cops2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	93,562,765 - 93,589,013 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	11,410,543 - 11,437,096 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	11,412,147 - 11,437,056 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

COPS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	122,542,387 - 122,578,858 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	122,542,324 - 122,574,462 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	136,383,684 - 136,398,318 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

COPS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	34,136,457 - 34,167,810 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	34,136,486 - 34,168,236 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666048	106,960,535 - 106,992,118 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cops2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	10,652,628 - 10,678,353 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624731	10,652,556 - 10,679,481 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cops2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	104,162,573 - 104,188,033 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cops2
135 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	89
Count of miRNA genes:	70
Interacting mature miRNAs:	79
Transcripts:	ENSRNOT00000012287
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582233	Insul10	Insulin level QTL 10	5.4	0.0015	blood insulin amount (VT:0001560)	serum insulin level times blood glucose level (CMO:0002040)	3	133259579	178259579	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	96509147	141509147	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	73592512	136118980	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	58601291	153936591	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	122654702	136118980	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	116582412	136118980	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	85062224	136118980	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	85062224	136118980	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	104545086	149545086	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	133134628	178134628	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	81425008	141509147	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	70845569	136091483	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	93829559	138829559	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	112250810	157250810	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	101255536	134750886	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	96509147	141509147	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	117537367	162537367	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	125116475	170116475	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	110225882	155225882	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	90755164	141509147	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	122395989	167395989	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	131036586	176036586	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	131036586	176036586	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	125814931	139636791	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	110634702	155634702	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	116188400	161188400	Rat

Markers in Region

WI-15995

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	113,085,488 - 113,085,633 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	118,110,709 - 118,110,853	NCBI	Rnor6.0
Rnor_5.0	3	124,633,200 - 124,633,344	UniSTS	Rnor5.0
RGSC_v3.4	3	113,142,053 - 113,142,197	UniSTS	RGSC3.4
Celera	3	111,940,311 - 111,940,455	UniSTS
Cytogenetic Map	3	q36	UniSTS

AI315723

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	113,084,367 - 113,084,619 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	118,109,588 - 118,109,839	NCBI	Rnor6.0
Rnor_5.0	3	124,632,079 - 124,632,330	UniSTS	Rnor5.0
RGSC_v3.4	3	113,140,932 - 113,141,183	UniSTS	RGSC3.4
Celera	3	111,939,190 - 111,939,441	UniSTS
Cytogenetic Map	3	q36	UniSTS

AI169377

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	113,085,523 - 113,085,759 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	118,110,744 - 118,110,979	NCBI	Rnor6.0
Rnor_5.0	3	124,633,235 - 124,633,470	UniSTS	Rnor5.0
RGSC_v3.4	3	113,142,088 - 113,142,323	UniSTS	RGSC3.4
Celera	3	111,940,346 - 111,940,581	UniSTS
RH 3.4 Map	3	1001.9	UniSTS
Cytogenetic Map	3	q36	UniSTS

BI283477

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	113,084,944 - 113,085,160 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	118,110,165 - 118,110,380	NCBI	Rnor6.0
Rnor_5.0	3	124,632,656 - 124,632,871	UniSTS	Rnor5.0
RGSC_v3.4	3	113,141,509 - 113,141,724	UniSTS	RGSC3.4
Celera	3	111,939,767 - 111,939,982	UniSTS
RH 3.4 Map	3	1001.3	UniSTS
Cytogenetic Map	3	q36	UniSTS

RH139241

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	113,084,817 - 113,084,966 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	118,110,038 - 118,110,186	NCBI	Rnor6.0
Rnor_5.0	3	124,632,529 - 124,632,677	UniSTS	Rnor5.0
RGSC_v3.4	3	113,141,382 - 113,141,530	UniSTS	RGSC3.4
Celera	3	111,939,640 - 111,939,788	UniSTS
Cytogenetic Map	3	q36	UniSTS

BF390689

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	113,100,996 - 113,101,183 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	118,128,033 - 118,128,219	NCBI	Rnor6.0
Rnor_5.0	3	124,652,470 - 124,652,656	UniSTS	Rnor5.0
RGSC_v3.4	3	113,157,171 - 113,157,357	UniSTS	RGSC3.4
Celera	3	111,955,698 - 111,955,884	UniSTS
RH 3.4 Map	3	1000.8	UniSTS
Cytogenetic Map	3	q36	UniSTS

RH127158

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	113,085,628 - 113,085,826 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	118,110,849 - 118,111,046	NCBI	Rnor6.0
Rnor_5.0	3	124,633,340 - 124,633,537	UniSTS	Rnor5.0
RGSC_v3.4	3	113,142,193 - 113,142,390	UniSTS	RGSC3.4
Celera	3	111,940,451 - 111,940,648	UniSTS
Cytogenetic Map	3	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001429755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_153297	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB081072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227565	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000012287 ⟹ ENSRNOP00000012287

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	118,110,705 - 118,137,125 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084154 ⟹ ENSRNOP00000075473

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	133,537,732 - 133,563,369 (-)	Ensembl
mRatBN7.2 Ensembl	3	113,084,176 - 113,109,947 (-)	Ensembl
Rnor_6.0 Ensembl	3	118,109,406 - 118,137,191 (-)	Ensembl

RefSeq Acc Id:

NM_153297 ⟹ NP_695209

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	133,538,889 - 133,563,493 (-)	NCBI
mRatBN7.2	3	113,085,485 - 113,110,090 (-)	NCBI
Rnor_6.0	3	118,110,705 - 118,137,125 (-)	NCBI
Rnor_5.0	3	124,631,885 - 124,661,562 (-)	NCBI
RGSC_v3.4	3	113,142,049 - 113,166,263 (-)	RGD
Celera	3	111,940,307 - 111,964,790 (-)	RGD

Sequence:

show sequence

AGGTCGAGCACCTTGGTTCCGGAATGAGCTCTCTCTTCTCCAGGAGAGACCCGAAGACTAGGAG
AATCGGGAGTGACGCTTCTGGGCCGCGGAGCCTGTGGGAGGAGGCTGTCTCTAATTTCTCCTCT
CCCCCTCCCCCCTCCGGCCAAGATGTCTGACATGGAGGATGATTTCATGTGCGATGATGAGGAG
GACTACGACCTGGAATACTCTGAAGACAGTAACTCTGAGCCCAACGTGGATTTGGAAAATCAGT
ACTATAATTCCAAAGCACTGAAAGAAGATGACCCGAAAGCAGCACTAAGCAGCTTCCAAAAGGT
TTTGGAACTCGAAGGTGAGAAGGGAGAATGGGGATTCAAAGCGCTAAAACAGATGATCAAGATT
AACTTCAAGCTGACAAACTTTCCAGAAATGATGAACAGATATAAGCAACTATTGACCTATATTC
GGAGTGCAGTCACCAGGAACTACTCTGAAAAGTCTATTAACTCTATCCTTGACTATATCTCCAC
TTCTAAACAGATGGATTTACTGCAGGAATTTTATGAAACAACACTGGAAGCTTTGAAAGATGCT
AAGAATGATAGACTGTGGTTTAAGACAAACACAAAGCTTGGAAAATTATATTTAGAACGAGAAG
AATATGGAAAGCTTCAAAAAATTTTACGCCAGTTACATCAGTCTTGTCAGACTGATGATGGAGA
AGATGACCTGAAAAAAGGTACCCAGTTATTAGAAATCTATGCTTTGGAAATTCAAATGTACACG
GCACAGAAGAACAACAAAAAGCTTAAAGCGCTCTATGAGCAATCACTTCATATCAAGTCTGCCA
TCCCTCACCCACTGATCATGGGTGTCATCAGAGAATGTGGTGGTAAGATGCACTTGAGAGAAGG
TGAATTTGAAAAGGCACACACTGATTTTTTTGAAGCTTTCAAGAATTATGATGAATCAGGAAGC
CCAAGACGAACCACTTGTTTAAAATATTTGGTCTTAGCAAATATGCTAATGAAATCAGGAATAA
ATCCATTTGACTCGCAAGAGGCCAAGCCGTATAAAAATGATCCAGAAATTCTAGCAATGACAAA
TTTAGTAAGTGCCTATCAGAACAATGACATCACCGAGTTTGAAAAGATTCTGAAAACAAATCAC
AGCAACATCATGGATGATCCTTTCATAAGAGAACACATTGAAGAGCTTTTACGAAACATCAGAA
CACAAGTCCTCATAAAGTTAATTAAGCCTTACACAAGAATACATATTCCTTTTATTTCTAAGGA
GCTAAACATAGACGTAGCTGATGTGGAAAGCTTGCTGGTGCAGTGCATACTGGATAACACTATT
CATGGCCGAATTGATCAAGTCAACCAGCTCCTTGAACTGGATCATCAGAAGAGGGGCGGTGCCC
GATATACTGCACTAGATAAATGGACCAACCAACTAAACTCTCTGAACCAGGCTGTGGTCAGTAA
ACTGGCTTAACGGAGAGCAAGCTTTGCAGACGTGCTTATGGCAACAGTCAGAGATGCAATCCTT
GGCGGACTGGAAAGGCAGAACTCCTGTGGTTGGTGTATCCTGAAAGTGACTGGAGTTATGGCAG
AAGGCCTTTTTTGATCAACTGGTTTGTGTATTGCTGCTGCATTTATCCAAGAAAAACAGATTTA
ATATTCCAGAAGAAAACCAAACACCATGGATTATGCTGTGTTGACGCCCTAACATACAACACCA
TAGTAATTGTCATGGGCAACATGACCAGAGAGATTTTGTCATGATTTAAATACACTGACACGCT
ACTGTTGGTTAAATTTAAACATGTTGTACCTGCAGAAATTCTCTCACAAATAACCTGCAATAAC
TTGAAATTCATACCCTTTTGAACACTTCCTTTTCTCATGTATAAATGAAAATGTTTGATGCATT
TTGCAAAATGTCAATTCTCCAAAACTGTGTCCGTCTACTTCTGTACTTGCAGCTAGTGAAGGTT
AGATGACCCGTGCCCTCTGTGGTCACTGTCAACTAGGGCTCAAGCAGCAAAATAAACAGTGCAG
CTCAG

hide sequence

RefSeq Acc Id:

XM_006234901 ⟹ XP_006234963

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	133,537,729 - 133,563,428 (-)	NCBI
mRatBN7.2	3	113,084,174 - 113,110,043 (-)	NCBI
Rnor_6.0	3	118,109,394 - 118,137,063 (-)	NCBI
Rnor_5.0	3	124,631,885 - 124,661,562 (-)	NCBI

Sequence:

show sequence

GAATCGGGAGTGACGCTTCTGGGCCGCGGAGCACTGTGGGAGGAGGCTGTCTCTAATTTCTCCT
CTCCCCCTCCCCCCTCCGGCCAAGATGTCTGACATGGAGGATGATTTCATGTGCGATGATGAGG
AGGACTACGACCTGGAATACTCTGAAGACAGTAACTCTGAGCCCAACGTGGATTTGGAAAATCA
GTACTATAATTCCAAAGCACTGAAAGAAGATGACCCGAAAGCAGCACTAAGCAGCTTCCAAAAG
GTTTTGGAACTCGAAGGTGAGAAGGGAGAATGGGGATTCAAAGCGCTAAAACAGATGATCAAGA
TTAACTTCAAGCTGACAAACTTTCCAGAAATGATGAACAGATATAAGCAACTATTGACCTATAT
TCGGAGTGCAGTCACCAGGAACTACTCTGAAAAGTCTATTAACTCTATCCTTGACTATATCTCC
ACTTCTAAACAGAATTCTGATTTTTTATGTCAGATGGATTTACTGCAGGAATTTTATGAAACAA
CACTGGAAGCTTTGAAAGATGCTAAGAATGATAGACTGTGGTTTAAGACAAACACAAAGCTTGG
AAAATTATATTTAGAACGAGAAGAATATGGAAAGCTTCAAAAAATTTTACGCCAGTTACATCAG
TCTTGTCAGACTGATGATGGAGAAGATGACCTGAAAAAAGGTACCCAGTTATTAGAAATCTATG
CTTTGGAAATTCAAATGTACACGGCACAGAAGAACAACAAAAAGCTTAAAGCGCTCTATGAGCA
ATCACTTCATATCAAGTCTGCCATCCCTCACCCACTGATCATGGGTGTCATCAGAGAATGTGGT
GGTAAGATGCACTTGAGAGAAGGTGAATTTGAAAAGGCACACACTGATTTTTTTGAAGCTTTCA
AGAATTATGATGAATCAGGAAGCCCAAGACGAACCACTTGTTTAAAATATTTGGTCTTAGCAAA
TATGCTAATGAAATCAGGAATAAATCCATTTGACTCGCAAGAGGCCAAGCCGTATAAAAATGAT
CCAGAAATTCTAGCAATGACAAATTTAGTAAGTGCCTATCAGAACAATGACATCACCGAGTTTG
AAAAGATTCTGAAAACAAATCACAGCAACATCATGGATGATCCTTTCATAAGAGAACACATTGA
AGAGCTTTTACGAAACATCAGAACACAAGTCCTCATAAAGTTAATTAAGCCTTACACAAGAATA
CATATTCCTTTTATTTCTAAGGAGCTAAACATAGACGTAGCTGATGTGGAAAGCTTGCTGGTGC
AGTGCATACTGGATAACACTATTCATGGCCGAATTGATCAAGTCAACCAGCTCCTTGAACTGGA
TCATCAGAAGAGGGGCGGTGCCCGATATACTGCACTAGATAAATGGACCAACCAACTAAACTCT
CTGAACCAGGCTGTGGTCAGTAAACTGGCTTAACGGAGAGCAAGCTTTGCAGACGTGCTTATGG
CAACAGTGCAGAGATGCAATCCTTGCGGACTGGAAAGGCAGAACTCCTGTGGGTTGGTGTATCC
TGAAAGTGACTGGAGTTATGGCAGAAGGGCTTTTTTGATCAACTGGTTTGTGTATTGCTGCTGC
ATTTATCCCAAGAAAAACAGCTTTAATCTCCAGAAGAAAACCAAAACACCATGGGATTTATGCT
GTGTTGACACCTTGCCCTAAACATACAACACCATAGTAATTTGTCATGGGCAACATGACCAGAG
AGATTTTTGTCATGATTTTAAATACACTGACACGCTACTGTTGGTTAAATTTAAACATGTTGTA
CCTGCAGAAATTCTCTCACAAATAACCTGCAATAACTTGAAATTCATACCCTTTTGAACACTTC
CTTTTCTCATGTATAAATGAAAATGTTTGCTGCATTTTGCAAAATGTCAATTCTCCAAAACTGT
GTCCGTCTACTTCTGTACTTGCAGCTAGTGAAGGTTAGATGACCCGTGCCCTCTGTGGTACACT
GTCACCTAGGGCTCAAGCAGCAAAATAAACAGTGCAGCTCAGAAATTGTAGCTTGGTTCTTGAT
GTGTTTTTATTACATTCGGGGTTAATCTTTTGTTTTTAGTATCTTACAATTTTCAGGTTATTTT
GTCTTCAGTTAAGATTTAAAAGCCTGAGAGCAAATAAGAAAAGCTAGTTCTTTGCTTTCAGGTT
TTTAAAATTACTGTTTATTGATAAAGTAAGGACTACTTTCAGGCAGAGCCCTTACATAGCACTT
GTTTTGACAGTGATAGTTTAAAGGATTACGATTCTTTTTTTAAAAAAAGAATGATAATTTTCTT
TTTAAAAGAGTATGTATTAACTCTCAGAATGTCACTTTAAACAAATATGCCAGAACATAGACAG
CGAAGTGAATGTTACCTGCATAGTGACCATGCTGAAAGGTTATTTTCTAACGCCAGCAACGAAC
CATTGCCCAAAGCCTCTTGGGTTTGCTCTTTGAGAATTACAGTCAAAGTTAATTTAGGTGACGT
GCTACTAACTTTATGTTTATACCTTGTTTGAAAAGAGTATTAACAGACTTGTCCGTCTTTGCCC
TAATTTGGCCCCAAATACCAGTTTCAGGGGAAAAAAAAAAAGCTAAATTTAGATAATGTAGAAA
GTATGTATCTGGCTTTGAAAACAATCCCAGAATAATTTTCAAGTATTTTGTGCAGTGGCAGCAT
AGTTAAGAATGAACTCTATGGCCTTTGATAGTGGCAGAACTCAGCTCATTTGAATGTATTGAGT
TTTGGATGTATTTGGTTTTTTTAAGTTCACATCGTATAGTGTCAAAAGAAAGAACTAAGATTAC
CATAATGTCCTTGGTTTTCTGTTGCTCATTATTATGTAAAGAGTTGAGTGGCAGTGCAGAAGGA
GGACTGTGTGACTGAAGAGTGGCAACCAAGAATTTTGATCATTAAATCAGATTTTATAAACAGT
AGAAAGAGCATGGACTTAAAACAAGGCATGCTTATTTGGTTTTGTCAAAATTTTACGAAAATAT
GTGATATATATTTATACTAAAACTATATAATCCTTAGATTTAGGAAAGCAGTCAGTTAATGTCT
AGCAGAATAAAGCAGTATTAAATACAGATATACGTTGGAAACTGTAGAAAACTGAAAGAAGACG
AAAGACGAAATGTCAATGGTAGGGAATAAAACATTTAAGATATTATGAAAGTATGTGTATTTTC
TTCTATTCTACATAAATCATTTGTGAAAAGTGTGTTCACGTTTTTTACAGGAGTGATATTAATT
AGGATTTATTTTTCCAATACAATTTGGAGACCCTTTGTTACCCAAATAAAAATGACAAGTTTCT
GTGCCTGTA

hide sequence

RefSeq Acc Id:

XM_039104395 ⟹ XP_038960323

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	133,537,729 - 133,563,428 (-)	NCBI
mRatBN7.2	3	113,086,361 - 113,110,043 (-)	NCBI

RefSeq Acc Id:

XM_063283173 ⟹ XP_063139243

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	133,538,881 - 133,563,428 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001416684	(Get FASTA)	NCBI Sequence Viewer
	NP_695209	(Get FASTA)	NCBI Sequence Viewer
	XP_006234963	(Get FASTA)	NCBI Sequence Viewer
	XP_038960323	(Get FASTA)	NCBI Sequence Viewer
	XP_063139243	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH61864	(Get FASTA)	NCBI Sequence Viewer
	BAC15575	(Get FASTA)	NCBI Sequence Viewer
	EDL80079	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000075473
	ENSRNOP00000075473.1
GenBank Protein	P61203	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_695209 ⟸ NM_153297

- UniProtKB:

Q6P731 (UniProtKB/Swiss-Prot), P61203 (UniProtKB/Swiss-Prot), A6HPX8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEK
GEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLL
QEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGT
QLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHT
DFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQN
NDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVAD
VESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA

hide sequence

RefSeq Acc Id:

XP_006234963 ⟸ XM_006234901

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEK
GEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNSDF
LCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGE
DDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREG
EFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTN
LVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKE
LNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSK
LA

hide sequence

Ensembl Acc Id:

ENSRNOP00000012287 ⟸ ENSRNOT00000012287

Ensembl Acc Id:

ENSRNOP00000075473 ⟸ ENSRNOT00000084154

RefSeq Acc Id:	XP_038960323 ⟸ XM_039104395
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063139243 ⟸ XM_063283173
- Peptide Label:	isoform X3

Protein Domains

PCI

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P61203-F1-model_v2	AlphaFold	P61203	1-443	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692383

Promoter ID:

EPDNEW_R2908

Type:

multiple initiation site

Name:

Cops2_1

Description:

COP9 signalosome subunit 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	118,136,982 - 118,137,042	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628791	AgrOrtholog
BioCyc Gene	G2FUF-48031	BioCyc
Ensembl Genes	ENSRNOG00000008744	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000084154	ENTREZGENE
	ENSRNOT00000084154.2	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.40.570	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:5597874	IMAGE-MGC_LOAD
InterPro	26S_Proteasome/COP9_Components	UniProtKB/Swiss-Prot
	PCI_dom	UniProtKB/Swiss-Prot
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot
	WH_DNA-bd_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:261736	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72285	IMAGE-MGC_LOAD
NCBI Gene	261736	ENTREZGENE
PANTHER	26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2	UniProtKB/Swiss-Prot
Pfam	PCI	UniProtKB/Swiss-Prot
PhenoGen	Cops2	PhenoGen
PROSITE	PCI	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008744	RatGTEx
SMART	PAM	UniProtKB/Swiss-Prot
	PINT	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46785	UniProtKB/Swiss-Prot
	SSF48452	UniProtKB/Swiss-Prot
UniProt	A6HPX8	ENTREZGENE, UniProtKB/TrEMBL
	CSN2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6P731	ENTREZGENE
UniProt Secondary	Q6P731	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-03-20	Cops2	COP9 signalosome subunit 2	Cops2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-23	Cops2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	Cops2	COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Cops2	COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)	Trip15	tyroid receptor interacting protein 15	Symbol and Name updated	1299863	APPROVED
2003-02-27	Trip15	tyroid receptor interacting protein 15			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_regulation	mRNA is induced at an early stage of neuronal differentiation by retinoic acid	634483

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD