Copb2 (COPI coat complex subunit beta 2) - Rat Genome Database

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Gene: Copb2 (COPI coat complex subunit beta 2) Rattus norvegicus
Analyze
Symbol: Copb2 (Ensembl: AABR07071244.1)
Name: COPI coat complex subunit beta 2
RGD ID: 628746
Description: Enables protein kinase C binding activity. Predicted to be involved in Golgi vesicle transport and intracellular protein transport. Located in Golgi membrane. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 19. Orthologous to human COPB2 (COPI coat complex subunit beta 2); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta prime COP; beta'-coat protein; beta'-COP; coatomer protein complex subunit beta 2; coatomer protein complex, subunit beta 2 (beta prime); coatomer subunit beta'; MGC93460; p102; Rack2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,040,687 - 108,062,810 (+)NCBIGRCr8
mRatBN7.2899,161,324 - 99,183,452 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,161,350 - 99,185,197 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8104,829,033 - 104,851,106 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08103,028,302 - 103,050,376 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,870,802 - 100,892,876 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,582,339 - 106,603,763 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08106,024,920 - 106,047,170 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera898,569,531 - 98,591,507 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Copb2RatCOVID-19  ISOCOPB2 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Object Symbol
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Term
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Reference
Notes
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Original Reference(s)
Copb2Ratblepharophimosis, ptosis, and epicanthus inversus syndrome  ISOCOPB2 (Homo sapiens)8554872ClinVar Annotator: match by term: Blepharophimosis more ...ClinVar 
Copb2Ratgenetic disease  ISOCOPB2 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Copb2RatOsteoporosis, Childhood- or Juvenile-Onset, with Developmental Delay  ISOCOPB2 (Homo sapiens)8554872ClinVar Annotator: match by term: Osteoporosis more ...ClinVarPMID:25741868 more ...
Copb2Ratprimary autosomal recessive microcephaly 19  ISOCOPB2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Object Symbol
Species
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Original Reference(s)
Copb2Ratmicrocephaly  ISSCopb2 (Mus musculus)13592920OMIM:251200 more ...MouseDO 

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Object Symbol
Species
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Original Reference(s)
Copb2Rat(1->4)-beta-D-glucan multiple interactionsISOCopb2 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of COPB2 mRNACTDPMID:36331819
Copb2Rat1,2-dimethylhydrazine multiple interactionsISOCopb2 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COPB2 mRNACTDPMID:22206623
Copb2Rat17alpha-ethynylestradiol increases expressionISOCopb2 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of COPB2 mRNACTDPMID:17942748
Copb2Rat17alpha-ethynylestradiol multiple interactionsISOCopb2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COPB2 mRNACTDPMID:17942748
Copb2Rat17beta-estradiol increases expressionISOCOPB2 (Homo sapiens)6480464Estradiol results in increased expression of COPB2 mRNACTDPMID:16514628
Copb2Rat17beta-estradiol increases expressionISOCopb2 (Mus musculus)6480464Estradiol results in increased expression of COPB2 mRNACTDPMID:39298647
Copb2Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactionsISOCOPB2 (Homo sapiens)6480464Metribolone promotes the reaction [NDRG1 protein binds to COPB2 protein]CTDPMID:17220478
Copb2Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOCopb2 (Mus musculus)64804642 more ...CTDPMID:30294300
Copb2Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOCOPB2 (Homo sapiens)64804642 more ...CTDPMID:31675489
Copb2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOCopb2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of COPB2 mRNACTDPMID:17942748
Copb2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCopb2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of COPB2 mRNACTDPMID:21570461
Copb2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCopb2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COPB2 mRNACTDPMID:17942748
Copb2Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of COPB2 mRNACTDPMID:21346803
Copb2Rat2,6-dimethoxyphenol multiple interactionsISOCOPB2 (Homo sapiens)6480464[Furaldehyde co-treated with pyrogallol 1 more ...CTDPMID:38598786
Copb2Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of COPB2 mRNACTDPMID:21346803
Copb2Rat2-hydroxypropanoic acid decreases expressionISOCOPB2 (Homo sapiens)6480464Lactic Acid results in decreased expression of COPB2 mRNACTDPMID:30851411
Copb2Rat3,4-methylenedioxymethamphetamine decreases expressionISOCopb2 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of COPB2 mRNACTDPMID:26251327
Copb2Rat3H-1,2-dithiole-3-thione decreases expressionEXP 64804641 and 2-dithiol-3-thione results in decreased expression of COPB2 mRNACTDPMID:19162173
Copb2Rat4,4'-sulfonyldiphenol increases expressionISOCopb2 (Mus musculus)6480464bisphenol S results in increased expression of COPB2 mRNACTDPMID:39298647
Copb2Rat4,4'-sulfonyldiphenol increases expressionISOCOPB2 (Homo sapiens)6480464bisphenol S results in increased expression of COPB2 proteinCTDPMID:34186270

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Biological Process
1 to 14 of 14 rows

  
Object Symbol
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Original Reference(s)
Copb2Ratendoplasmic reticulum to Golgi vesicle-mediated transport involved_inIBAPANTHER:PTN000458798 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Copb2Ratintra-Golgi vesicle-mediated transport involved_inIEAUniProtKB:P35606 and ensembl:ENSP000003294191600115GO_REF:0000107EnsemblGO_REF:0000107
Copb2Ratintra-Golgi vesicle-mediated transport involved_inIBAPANTHER:PTN000458798 and UniProtKB:P356061600115GO_REF:0000033GO_CentralGO_REF:0000033
Copb2Ratintra-Golgi vesicle-mediated transport involved_inISOCOPB2 (Homo sapiens)1624291 PMID:8335000RGDPMID:8335000
Copb2Ratintracellular protein transport involved_inIEAUniRule:UR0004357851600115GO_REF:0000104UniProtGO_REF:0000104
Copb2Ratintracellular protein transport involved_inIEAInterPro:IPR0066921600115GO_REF:0000002InterProGO_REF:0000002
Copb2Ratintracellular protein transport involved_inIBAPANTHER:PTN000458798 and WB:WBGene000095421600115GO_REF:0000033GO_CentralGO_REF:0000033
Copb2Ratprotein transport involved_inIEAUniProtKB-KW:KW-06531600115GO_REF:0000043UniProtGO_REF:0000043
Copb2Ratretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum involved_inIEAUniProtKB:P35606 and ensembl:ENSP000003294191600115GO_REF:0000107EnsemblGO_REF:0000107
Copb2Ratretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum involved_inIBAPANTHER:PTN000458798 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Copb2Ratretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum involved_inISOCOPB2 (Homo sapiens)1624291 PMID:34450031RGDPMID:34450031
Copb2Ratretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum involved_inISSUniProtKB:P356061600115GO_REF:0000024UniProtGO_REF:0000024
Copb2Ratvesicle-mediated transport involved_inIEAUniProtKB-KW:KW-09311600115GO_REF:0000043UniProtGO_REF:0000043
Copb2Ratvesicle-mediated transport involved_inIEAInterPro:IPR0066921600115GO_REF:0000002InterProGO_REF:0000002
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Cellular Component
1 to 17 of 17 rows

  
Object Symbol
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Evidence
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Reference
Notes
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Original Reference(s)
Copb2RatCOPI vesicle coat part_ofISOCOPB2 (Homo sapiens)1624291 PMID:14729954 and PMID:8335000RGDPMID:14729954 and PMID:8335000
Copb2RatCOPI vesicle coat part_ofIBAFB:FBgn0025724 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Copb2RatCOPI vesicle coat part_ofIEAUniProtKB:P35606 and ensembl:ENSP000003294191600115GO_REF:0000107EnsemblGO_REF:0000107
Copb2RatCOPI-coated vesicle membrane located_inIEAUniProtKB-SubCell:SL-00761600115GO_REF:0000044UniProtGO_REF:0000044
Copb2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Copb2Ratcytoplasmic vesicle located_inIEAUniProtKB-KW:KW-09681600115GO_REF:0000043UniProtGO_REF:0000043
Copb2Ratcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Copb2RatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
Copb2RatGolgi apparatus located_inISOCopb2 (Mus musculus)1624291 PMID:20724702 and PMID:8947846RGDPMID:20724702 and PMID:8947846
Copb2RatGolgi apparatus located_inIDA 8554056PMID:15728249MGI 
Copb2RatGolgi apparatus located_inIEAARBA:ARBA000287081600115GO_REF:0000117UniProtGO_REF:0000117
Copb2RatGolgi apparatus located_inIEAUniProtKB:O55029 and ensembl:ENSMUSP000000350331600115GO_REF:0000107EnsemblGO_REF:0000107
Copb2RatGolgi membrane  IDA 727623 RGD 
Copb2RatGolgi membrane located_inIEAUniRule:UR0004357851600115GO_REF:0000104UniProtGO_REF:0000104
Copb2RatGolgi membrane located_inIEAUniProtKB-SubCell:SL-01341600115GO_REF:0000044UniProtGO_REF:0000044
Copb2Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Copb2Ratmembrane coat part_ofIEAInterPro:IPR0066921600115GO_REF:0000002InterProGO_REF:0000002
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Molecular Function

  
Object Symbol
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Reference
Notes
Source
Original Reference(s)
Copb2Ratprotein binding  IPIPrkce (Rattus norvegicus)727623 RGD 
Copb2Ratprotein binding enablesISOCOPB2 (Homo sapiens)1624291UniProtKB:P0DTC2 more ...RGDPMID:21988832 more ...
Copb2Ratprotein binding enablesIPIUniProtKB:Q9EQC58554152PMID:18556652UniProt 
Copb2Ratprotein kinase C binding  IPIPrkce (Rattus norvegicus)727623 RGD 
Copb2Ratstructural molecule activity enablesIEAUniRule:UR0004357851600115GO_REF:0000104UniProtGO_REF:0000104
Copb2Ratstructural molecule activity enablesIEAInterPro:IPR0066921600115GO_REF:0000002InterProGO_REF:0000002


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#
Reference Title
Reference Citation
1. A systematic analysis of 40 random genes in cultured vascular smooth muscle subtypes reveals a heterogeneity of gene expression and identifies the tight junction gene zonula occludens 2 as a marker of epithelioid "pup" smooth muscle cells and a participant in carotid neointimal formation. Adams LD, etal., Arterioscler Thromb Vasc Biol 1999 Nov;19(11):2600-8.
2. Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic. Burman JL, etal., J Biol Chem. 2008 Aug 15;283(33):22774-86. doi: 10.1074/jbc.M801869200. Epub 2008 Jun 13.
3. The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon. Csukai M, etal., J Biol Chem 1997 Nov 14;272(46):29200-6.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. Loh E, etal., J Cell Sci. 2005 Mar 15;118(Pt 6):1209-22. Epub 2005 Feb 22.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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PMID:8335000   PMID:8947846   PMID:12477932   PMID:14729954   PMID:15358183   PMID:16854843   PMID:18434597   PMID:18504258   PMID:19631211   PMID:20724702   PMID:20801885   PMID:22871113  
PMID:23716698   PMID:24625528   PMID:25002582  



Copb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,040,687 - 108,062,810 (+)NCBIGRCr8
mRatBN7.2899,161,324 - 99,183,452 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,161,350 - 99,185,197 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8104,829,033 - 104,851,106 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08103,028,302 - 103,050,376 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,870,802 - 100,892,876 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,582,339 - 106,603,763 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08106,024,920 - 106,047,170 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera898,569,531 - 98,591,507 (+)NCBICelera
Cytogenetic Map8q31NCBI
COPB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383139,357,406 - 139,389,680 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3139,353,946 - 139,389,736 (-)EnsemblGRCh38hg38GRCh38
GRCh373139,076,248 - 139,108,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,559,123 - 140,591,151 (-)NCBINCBI36Build 36hg18NCBI36
Build 343140,559,132 - 140,591,159NCBI
Celera3137,499,384 - 137,531,480 (-)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3136,451,880 - 136,483,977 (-)NCBIHuRef
CHM1_13139,039,998 - 139,072,089 (-)NCBICHM1_1
T2T-CHM13v2.03142,104,959 - 142,137,239 (-)NCBIT2T-CHM13v2.0
Copb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,445,784 - 98,470,428 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,445,774 - 98,470,435 (+)EnsemblGRCm39 Ensembl
GRCm38998,563,731 - 98,588,375 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,563,721 - 98,588,382 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,464,150 - 98,488,794 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36998,373,083 - 98,397,727 (+)NCBIMGSCv36mm8
Celera998,109,355 - 98,134,004 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.4NCBI
Copb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555086,201,989 - 6,231,845 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555086,201,989 - 6,231,840 (+)NCBIChiLan1.0ChiLan1.0
COPB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,271,754 - 137,303,751 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13137,272,816 - 137,308,481 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,394,480 - 136,426,544 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13143,994,312 - 144,026,277 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3143,994,312 - 144,020,117 (-)Ensemblpanpan1.1panPan2
COPB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12335,536,520 - 35,604,708 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2335,536,615 - 35,566,569 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2335,524,048 - 35,592,583 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02336,075,179 - 36,143,336 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2336,074,618 - 36,143,348 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12335,755,206 - 35,823,768 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02335,828,808 - 35,896,988 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02336,070,552 - 36,139,285 (-)NCBIUU_Cfam_GSD_1.0
Copb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560274,727,380 - 74,753,469 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365401,467,169 - 1,493,258 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365401,467,169 - 1,493,218 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COPB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1380,218,989 - 80,264,762 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11380,220,460 - 80,264,808 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21387,894,952 - 87,931,027 (-)NCBISscrofa10.2Sscrofa10.2susScr3
COPB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11551,165,275 - 51,197,971 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604124,142,863 - 24,183,665 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Copb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473015,908,551 - 15,936,856 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473015,908,551 - 15,936,886 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Copb2
158 total Variants

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:22
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000075603
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 29 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)888612425107550209Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat

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RH129978  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2899,183,240 - 99,183,443 (+)MAPPERmRatBN7.2
Rnor_6.08106,603,550 - 106,603,754NCBIRnor6.0
Celera898,591,295 - 98,591,498UniSTS
RH 3.4 Map81051.7UniSTS
AU048956  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2899,163,041 - 99,163,284 (+)MAPPERmRatBN7.2
Rnor_6.08106,584,071 - 106,584,313NCBIRnor6.0
Celera898,571,234 - 98,571,480UniSTS







Ensembl Acc Id: ENSRNOT00000080434   ⟹   ENSRNOP00000071536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl899,165,660 - 99,181,530 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101351   ⟹   ENSRNOP00000094254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl899,161,350 - 99,185,197 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115328   ⟹   ENSRNOP00000088501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl899,165,521 - 99,185,197 (+)Ensembl
RefSeq Acc Id: NM_021765   ⟹   NP_068533
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88108,040,687 - 108,062,810 (+)NCBI
mRatBN7.2899,161,324 - 99,183,452 (+)NCBI
Rnor_6.08106,582,339 - 106,603,763 (+)NCBI
Rnor_5.08106,024,920 - 106,047,170 (+)NCBI
Celera898,569,531 - 98,591,507 (+)RGD
Sequence:
Protein RefSeqs NP_068533 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB38315 (Get FASTA)   NCBI Sequence Viewer  
  AAB88018 (Get FASTA)   NCBI Sequence Viewer  
  AAH88397 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000094254
GenBank Protein O35142 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_068533   ⟸   NM_021765
- UniProtKB: A0A8I6GKN2 (UniProtKB/TrEMBL),   A6I2B6 (UniProtKB/TrEMBL),   Q5M7X1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071536   ⟸   ENSRNOT00000080434
Ensembl Acc Id: ENSRNOP00000094254   ⟸   ENSRNOT00000101351
Ensembl Acc Id: ENSRNOP00000088501   ⟸   ENSRNOT00000115328
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0P9-F1-model_v2 AlphaFold A0A0G2K0P9 1-733 view protein structure
AF-O35142-F1-model_v2 AlphaFold O35142 1-905 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29416 BioCyc
Ensembl Genes ENSRNOG00000060723 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000101351 ENTREZGENE
Gene3D-CATH 1.25.40.470 UniProtKB/Swiss-Prot
  2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7190660 IMAGE-MGC_LOAD
InterPro Coatomer_complex_subunit UniProtKB/Swiss-Prot
  Coatomer_WD-assoc_reg UniProtKB/Swiss-Prot
  COPB2 UniProtKB/Swiss-Prot
  G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:60384 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93460 IMAGE-MGC_LOAD
NCBI Gene 60384 ENTREZGENE
PANTHER COATOMER UniProtKB/Swiss-Prot
  COATOMER SUBUNIT BETA UniProtKB/Swiss-Prot
Pfam Coatomer_WDAD UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
PhenoGen Copb2 PhenoGen
PIRSF Coatomer_beta'_subunit UniProtKB/Swiss-Prot
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000060723 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A0G2K0P9_RAT UniProtKB/TrEMBL
  A0A8I6AA32_RAT UniProtKB/TrEMBL
  A0A8I6GKN2 ENTREZGENE, UniProtKB/TrEMBL
  A6I2B6 ENTREZGENE, UniProtKB/TrEMBL
  COPB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5M7X1 ENTREZGENE, UniProtKB/TrEMBL
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-11 Copb2  COPI coat complex subunit beta 2  Copb2  coatomer protein complex subunit beta 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-13 Copb2  coatomer protein complex subunit beta 2  Copb2  coatomer protein complex, subunit beta 2 (beta prime)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Copb2  coatomer protein complex, subunit beta 2 (beta prime)    beta prime COP  Name updated 1299863 APPROVED
2003-02-27 Copb2  beta prime COP      Symbol and Name status set to provisional 70820 PROVISIONAL