Mcfd2 (multiple coagulation factor deficiency 2, ER cargo receptor complex subunit) - Rat Genome Database

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Gene: Mcfd2 (multiple coagulation factor deficiency 2, ER cargo receptor complex subunit) Rattus norvegicus
Analyze
Symbol: Mcfd2
Name: multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
RGD ID: 628690
Description: Predicted to enable calcium ion binding activity. Acts upstream of or within carboxylic acid metabolic process. Located in extracellular region. Biomarker of transient cerebral ischemia. Orthologous to human MCFD2 (multiple coagulation factor deficiency 2, ER cargo receptor complex subunit); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: multiple coagulation factor deficiency 2; multiple coagulation factor deficiency protein 2 homolog; neural stem cell-derived neuronal survival protein; Sdnsf; stem cell derived neuronal survival protein; stem cell derived neuronal survival protein precursor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8613,028,036 - 13,039,388 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl613,016,104 - 13,039,379 (+)EnsemblGRCr8
mRatBN7.267,274,469 - 7,285,841 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl67,274,469 - 7,285,841 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx67,555,619 - 7,566,928 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.067,865,043 - 7,876,352 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.067,392,168 - 7,403,477 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0610,887,303 - 10,899,221 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl610,887,288 - 10,899,200 (-)Ensemblrn6Rnor6.0
Rnor_5.0620,875,389 - 20,887,306 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4610,763,516 - 10,774,854 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera67,023,091 - 7,034,429 (+)NCBICelera
RGSC_v3.1610,763,515 - 10,774,854 (-)NCBI
Cytogenetic Map6q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
clotrimazole  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
gentamycin  (EXP)
indometacin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
monosodium L-glutamate  (EXP)
N,N-diethyl-m-toluamide  (EXP)
ozone  (ISO)
paracetamol  (ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mutations in the MCFD2 gene are predominant among patients with hereditary combined FV and FVIII deficiency (F5F8D) in India. Jayandharan G, etal., Haemophilia. 2007 Jul;13(4):413-9.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Stem cell-derived neural stem/progenitor cell supporting factor is an autocrine/paracrine survival factor for adult neural stem/progenitor cells. Toda H, etal., J Biol Chem 2003 Sep 12;278(37):35491-500.
Additional References at PubMed
PMID:17612595  


Genomics

Comparative Map Data
Mcfd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8613,028,036 - 13,039,388 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl613,016,104 - 13,039,379 (+)EnsemblGRCr8
mRatBN7.267,274,469 - 7,285,841 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl67,274,469 - 7,285,841 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx67,555,619 - 7,566,928 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.067,865,043 - 7,876,352 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.067,392,168 - 7,403,477 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0610,887,303 - 10,899,221 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl610,887,288 - 10,899,200 (-)Ensemblrn6Rnor6.0
Rnor_5.0620,875,389 - 20,887,306 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4610,763,516 - 10,774,854 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera67,023,091 - 7,034,429 (+)NCBICelera
RGSC_v3.1610,763,515 - 10,774,854 (-)NCBI
Cytogenetic Map6q12NCBI
MCFD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38246,901,870 - 46,941,855 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl246,901,870 - 46,941,855 (-)Ensemblhg38GRCh38
GRCh37247,129,009 - 47,168,994 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36246,982,517 - 46,996,453 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34247,040,667 - 47,054,600NCBI
Celera246,967,630 - 47,007,856 (-)NCBICelera
Cytogenetic Map2p21NCBI
HuRef246,866,270 - 46,906,310 (-)NCBIHuRef
CHM1_1247,059,303 - 47,099,278 (-)NCBICHM1_1
T2T-CHM13v2.0246,906,646 - 46,946,631 (-)NCBIT2T-CHM13v2.0
Mcfd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391787,561,871 - 87,573,382 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1787,561,871 - 87,573,363 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381787,254,443 - 87,265,947 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1787,254,443 - 87,265,935 (-)Ensemblmm10GRCm38
MGSCv371787,653,783 - 87,665,287 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361787,162,769 - 87,174,241 (-)NCBIMGSCv36mm8
Celera1791,645,568 - 91,657,364 (-)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1757.06NCBI
Mcfd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544113,764,144 - 13,777,628 (-)Ensembl
ChiLan1.0NW_00495544113,766,683 - 13,776,305 (-)NCBIChiLan1.0ChiLan1.0
MCFD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21279,473,963 - 79,488,153 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A79,477,946 - 79,492,124 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A47,012,550 - 47,031,725 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A47,950,679 - 47,962,005 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A47,950,679 - 47,987,407 (-)EnsemblpanPan2panpan1.1
MCFD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11049,091,466 - 49,101,769 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1049,092,908 - 49,101,775 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1048,944,989 - 48,955,352 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01049,961,866 - 49,972,101 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1049,961,874 - 50,001,189 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11049,669,845 - 49,680,077 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01049,959,594 - 49,969,896 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01050,143,441 - 50,153,684 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mcfd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629233,963,670 - 33,991,418 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365085,410,674 - 5,420,012 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365085,392,275 - 5,419,267 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCFD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl393,620,936 - 93,633,015 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1393,620,921 - 93,633,018 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2399,712,888 - 99,719,379 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MCFD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11460,273,274 - 60,283,919 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1460,273,296 - 60,287,200 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604551,560,975 - 51,572,057 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mcfd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473828,324,894 - 28,337,730 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473828,325,154 - 28,333,241 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mcfd2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v175,710,038 - 5,721,777 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mcfd2
86 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:97
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000020328
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6125740059Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6120510098Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat

Markers in Region
RH128627  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X119,708,403 - 119,708,611 (-)MAPPERmRatBN7.2
mRatBN7.267,285,551 - 7,285,759 (-)MAPPERmRatBN7.2
mRatBN7.267,285,551 - 7,285,759 (+)MAPPERmRatBN7.2
mRatBN7.2X119,708,403 - 119,708,611 (+)MAPPERmRatBN7.2
Rnor_6.0610,887,385 - 10,887,592NCBIRnor6.0
Rnor_6.0X127,036,271 - 127,036,478NCBIRnor6.0
Rnor_5.0620,875,471 - 20,875,678UniSTSRnor5.0
Rnor_5.0X127,131,618 - 127,131,825UniSTSRnor5.0
RGSC_v3.4X4,288,794 - 4,289,001UniSTSRGSC3.4
RGSC_v3.4610,763,598 - 10,763,805UniSTSRGSC3.4
Celera67,034,140 - 7,034,347UniSTS
CeleraX118,844,147 - 118,844,354UniSTS
Cytogenetic Map6q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020328   ⟹   ENSRNOP00000020328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl610,889,069 - 10,891,146 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000089104   ⟹   ENSRNOP00000069872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl613,027,948 - 13,039,379 (+)Ensembl
mRatBN7.2 Ensembl67,274,469 - 7,285,841 (+)Ensembl
Rnor_6.0 Ensembl610,887,288 - 10,899,200 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000141366   ⟹   ENSRNOP00000099651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl613,016,104 - 13,039,379 (+)Ensembl
RefSeq Acc Id: NM_139253   ⟹   NP_640346
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8613,028,050 - 13,039,388 (+)NCBI
mRatBN7.267,274,502 - 7,285,841 (+)NCBI
Rnor_6.0610,887,303 - 10,899,183 (-)NCBI
Rnor_5.0620,875,389 - 20,887,306 (-)NCBI
RGSC_v3.4610,763,516 - 10,774,854 (-)RGD
Celera67,023,091 - 7,034,429 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239711   ⟹   XP_006239773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8613,028,036 - 13,039,388 (+)NCBI
mRatBN7.267,274,469 - 7,285,841 (+)NCBI
Rnor_6.0610,888,768 - 10,899,202 (-)NCBI
Rnor_5.0620,875,389 - 20,887,306 (-)NCBI
Sequence:
RefSeq Acc Id: NP_640346   ⟸   NM_139253
- Peptide Label: precursor
- UniProtKB: Q8K5B3 (UniProtKB/Swiss-Prot),   Q6GQY2 (UniProtKB/TrEMBL),   A0A0G2JWG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239773   ⟸   XM_006239711
- Peptide Label: isoform X1
- UniProtKB: Q8K5B3 (UniProtKB/Swiss-Prot),   Q6GQY2 (UniProtKB/TrEMBL),   A0A0G2JWG5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069872   ⟸   ENSRNOT00000089104
Ensembl Acc Id: ENSRNOP00000020328   ⟸   ENSRNOT00000020328
Ensembl Acc Id: ENSRNOP00000099651   ⟸   ENSRNOT00000141366
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K5B3-F1-model_v2 AlphaFold Q8K5B3 1-145 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694392
Promoter ID:EPDNEW_R4917
Type:multiple initiation site
Name:Mcfd2_1
Description:multiple coagulation factor deficiency 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0610,899,160 - 10,899,220EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628690 AgrOrtholog
BioCyc Gene G2FUF-38717 BioCyc
Ensembl Genes ENSRNOG00000015059 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000089104 ENTREZGENE
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7100216 IMAGE-MGC_LOAD
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  ER-Golgi_Adhesion_Reg UniProtKB/Swiss-Prot
KEGG Report rno:246117 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91471 IMAGE-MGC_LOAD
NCBI Gene 246117 ENTREZGENE
PANTHER MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 UniProtKB/Swiss-Prot
  MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN UniProtKB/Swiss-Prot
Pfam EF-hand_7 UniProtKB/Swiss-Prot
PhenoGen Mcfd2 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015059 RatGTEx
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A0A0G2JWG5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0KXV0_RAT UniProtKB/TrEMBL
  A6H9D9_RAT UniProtKB/TrEMBL
  A6H9E3_RAT UniProtKB/TrEMBL
  MCFD2_RAT UniProtKB/Swiss-Prot
  Q6GQY2 ENTREZGENE, UniProtKB/TrEMBL
  Q8K5B3 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-19 Mcfd2  multiple coagulation factor deficiency 2, ER cargo receptor complex subunit  Mcfd2  multiple coagulation factor deficiency 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-04-25 Mcfd2  multiple coagulation factor deficiency 2  Mcfd2  multiple coagulation factor deficiency 2, ER cargo receptor complex subunit  Name changed 629549 APPROVED
2019-11-11 Mcfd2  multiple coagulation factor deficiency 2, ER cargo receptor complex subunit  Mcfd2  multiple coagulation factor deficiency 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Mcfd2  multiple coagulation factor deficiency 2  Sdnsf  stem cell derived neuronal survival protein precursor  Symbol and Name updated 1299863 APPROVED
2003-02-27 Sdnsf  stem cell derived neuronal survival protein precursor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation expression is upregulated by induced neurogenesis status seen in ischemically treated hippocampus 724668