Cenpf (centromere protein F) - Rat Genome Database

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Gene: Cenpf (centromere protein F) Rattus norvegicus
Analyze
Symbol: Cenpf
Name: centromere protein F
RGD ID: 628667
Description: Predicted to enable DNA-binding transcription factor binding activity; dynein complex binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including metaphase chromosome alignment; regulation of G2/M transition of mitotic cell cycle; and ventricular system development. Predicted to act upstream of or within regulation of striated muscle tissue development. Predicted to be located in several cellular components, including cytoskeleton; midbody; and nucleus. Predicted to be part of ciliary transition fiber and outer kinetochore. Predicted to be active in chromosome, centromeric region; nucleus; and spindle pole. Human ortholog(s) of this gene implicated in Stromme syndrome. Orthologous to human CENPF (centromere protein F); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: centromere autoantigen F; LEK/centromere protein; Lek1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813103,715,344 - 103,760,931 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13103,715,344 - 103,760,886 (-)EnsemblGRCr8
mRatBN7.213101,184,127 - 101,229,714 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13101,184,127 - 101,229,669 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13103,699,540 - 103,745,084 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013105,088,296 - 105,133,842 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013102,286,283 - 102,332,153 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013108,132,499 - 108,178,609 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13108,132,499 - 108,178,609 (-)Ensemblrn6Rnor6.0
Rnor_5.013112,758,855 - 112,804,965 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413105,920,242 - 105,965,655 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera13100,670,298 - 100,715,841 (-)NCBICelera
RGSC_v3.113106,125,141 - 106,126,183 (-)NCBI
Cytogenetic Map13q26NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (EXP)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cryptolepine  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDE  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diazinon  (EXP)
dieldrin  (EXP)
dimethylarsinic acid  (EXP)
dioxygen  (EXP,ISO)
diquat  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
etoposide  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
folpet  (ISO)
fructose  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glucose  (ISO)
glycidol  (EXP)
GW 7647  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
irinotecan  (ISO)
isobutanol  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
lithium chloride  (ISO)
lovastatin  (ISO)
lucanthone  (ISO)
malathion  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
mevalonic acid  (ISO)
miconazole  (ISO)
mitomycin C  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nickel dichloride  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl isothiocyanate  (EXP,ISO)
phenformin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
PhIP  (ISO)
pinosylvin  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
SP2509  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trans-pinosylvin  (ISO)
tremolite asbestos  (ISO)
triazines  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axoneme  (IEA,ISO)
centrosome  (IEA,ISO)
chromosome, centromeric region  (IBA,IEA,ISO)
ciliary basal body  (IEA,ISO)
ciliary transition fiber  (IEA,ISO)
cytoplasm  (IEA,ISO)
kinetochore  (IEA,ISO)
midbody  (IEA,ISO)
nuclear envelope  (IEA,ISO)
nuclear matrix  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
outer kinetochore  (IEA,ISO)
pronucleus  (IEA,ISO)
spindle  (IEA,ISO)
spindle pole  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The cloning and analysis of LEK1 identifies variations in the LEK/centromere protein F/mitosin gene family. Goodwin RL, etal., J Biol Chem 1999 Jun 25;274(26):18597-604.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7542657   PMID:7642639   PMID:7651420   PMID:7904902   PMID:9763420   PMID:11084331   PMID:12154071   PMID:12974617   PMID:15494374   PMID:15677469   PMID:15870278   PMID:16252009  
PMID:17363900   PMID:17600710   PMID:25564561   PMID:35527655  


Genomics

Comparative Map Data
Cenpf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813103,715,344 - 103,760,931 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13103,715,344 - 103,760,886 (-)EnsemblGRCr8
mRatBN7.213101,184,127 - 101,229,714 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13101,184,127 - 101,229,669 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13103,699,540 - 103,745,084 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013105,088,296 - 105,133,842 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013102,286,283 - 102,332,153 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013108,132,499 - 108,178,609 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13108,132,499 - 108,178,609 (-)Ensemblrn6Rnor6.0
Rnor_5.013112,758,855 - 112,804,965 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413105,920,242 - 105,965,655 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera13100,670,298 - 100,715,841 (-)NCBICelera
RGSC_v3.113106,125,141 - 106,126,183 (-)NCBI
Cytogenetic Map13q26NCBI
CENPF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381214,603,195 - 214,664,571 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1214,603,172 - 214,664,574 (+)Ensemblhg38GRCh38
GRCh371214,776,538 - 214,837,914 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361212,843,155 - 212,904,537 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341211,164,926 - 211,226,307NCBI
Celera1187,999,934 - 188,061,298 (+)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1185,450,388 - 185,511,761 (+)NCBIHuRef
CHM1_11216,048,789 - 216,110,152 (+)NCBICHM1_1
T2T-CHM13v2.01213,842,449 - 213,903,796 (+)NCBIT2T-CHM13v2.0
Cenpf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391189,372,803 - 189,420,302 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1189,372,803 - 189,420,283 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381189,640,606 - 189,688,107 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1189,640,606 - 189,688,086 (-)Ensemblmm10GRCm38
MGSCv371191,464,485 - 191,511,965 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361191,341,394 - 191,388,874 (-)NCBIMGSCv36mm8
Celera1196,559,635 - 196,607,121 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map195.03NCBI
Cenpf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554063,223,993 - 3,273,714 (-)Ensembl
ChiLan1.0NW_0049554063,225,788 - 3,273,037 (-)NCBIChiLan1.0ChiLan1.0
CENPF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2134,738,700 - 34,799,863 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1134,702,771 - 34,763,917 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01190,170,414 - 190,231,478 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11195,025,577 - 195,086,518 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1195,024,877 - 195,086,518 (+)EnsemblpanPan2panpan1.1
CENPF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1712,558,455 - 12,618,637 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl712,555,143 - 12,617,996 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha712,129,485 - 12,194,142 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0712,265,629 - 12,330,197 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl712,265,609 - 12,328,372 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1712,188,652 - 12,253,247 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0712,293,025 - 12,357,544 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0712,421,098 - 12,482,469 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cenpf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934461,632,209 - 61,686,939 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366283,643,000 - 3,695,221 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366283,642,281 - 3,695,262 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9128,948,498 - 129,012,218 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19128,948,386 - 129,012,241 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29141,675,880 - 141,740,104 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CENPF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12514,914,805 - 14,972,811 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2514,914,809 - 14,972,796 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605515,379,185 - 15,438,265 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cenpf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477119,656,981 - 19,702,625 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477119,657,489 - 19,702,506 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cenpf
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11067,710,777 - 67,756,495 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cenpf
333 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:147
Count of miRNA genes:111
Interacting mature miRNAs:131
Transcripts:ENSRNOT00000004525
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
RH143346  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213101,190,612 - 101,190,778 (+)MAPPERmRatBN7.2
Rnor_6.013108,138,984 - 108,139,149NCBIRnor6.0
Rnor_5.013112,765,340 - 112,765,505UniSTSRnor5.0
RGSC_v3.413105,926,598 - 105,926,763UniSTSRGSC3.4
Celera13100,676,784 - 100,676,949UniSTS
RH 3.4 Map13692.9UniSTS
Cytogenetic Map13q27UniSTS
RH138998  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213101,221,531 - 101,221,656 (+)MAPPERmRatBN7.2
Rnor_6.013108,170,472 - 108,170,596NCBIRnor6.0
Rnor_5.013112,796,828 - 112,796,952UniSTSRnor5.0
RGSC_v3.413105,957,518 - 105,957,642UniSTSRGSC3.4
RGSC_v3.42211,884,456 - 211,884,580UniSTSRGSC3.4
Celera13100,707,704 - 100,707,828UniSTS
RH 3.4 Map13691.8UniSTS
Cytogenetic Map13q27UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 66 163 91 90 59 92 59 6 354 190 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000004525   ⟹   ENSRNOP00000004525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13103,715,344 - 103,760,886 (-)Ensembl
mRatBN7.2 Ensembl13101,184,127 - 101,229,669 (-)Ensembl
Rnor_6.0 Ensembl13108,132,499 - 108,178,609 (-)Ensembl
RefSeq Acc Id: NM_001100827   ⟹   NP_001094297
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813103,715,344 - 103,760,886 (-)NCBI
mRatBN7.213101,184,127 - 101,229,669 (-)NCBI
Rnor_6.013108,132,499 - 108,178,609 (-)NCBI
Rnor_5.013112,758,855 - 112,804,965 (-)NCBI
RGSC_v3.413105,920,242 - 105,965,655 (-)RGD
Celera13100,670,298 - 100,715,841 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090398   ⟹   XP_038946326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813103,715,640 - 103,760,931 (-)NCBI
mRatBN7.213101,184,127 - 101,229,714 (-)NCBI
RefSeq Acc Id: XM_039090399   ⟹   XP_038946327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813103,715,640 - 103,760,741 (-)NCBI
mRatBN7.213101,184,127 - 101,229,478 (-)NCBI
RefSeq Acc Id: XM_039090400   ⟹   XP_038946328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813103,715,640 - 103,760,931 (-)NCBI
mRatBN7.213101,184,127 - 101,229,714 (-)NCBI
RefSeq Acc Id: XM_063272055   ⟹   XP_063128125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813103,722,261 - 103,760,931 (-)NCBI
RefSeq Acc Id: NP_001094297   ⟸   NM_001100827
- UniProtKB: A6JGV8 (UniProtKB/TrEMBL),   E9PT83 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004525   ⟸   ENSRNOT00000004525
RefSeq Acc Id: XP_038946328   ⟸   XM_039090400
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946326   ⟸   XM_039090398
- Peptide Label: isoform X1
- UniProtKB: A6JGV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946327   ⟸   XM_039090399
- Peptide Label: isoform X1
- UniProtKB: A6JGV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128125   ⟸   XM_063272055
- Peptide Label: isoform X3
- UniProtKB: A6JGV8 (UniProtKB/TrEMBL)
Protein Domains
Centromere protein Cenp-F leucine-rich repeat-   Kinetochore protein Cenp-F/LEK1 Rb protein-binding

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699104
Promoter ID:EPDNEW_R9629
Type:multiple initiation site
Name:Cenpf_1
Description:centromere protein F
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013108,178,604 - 108,178,664EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628667 AgrOrtholog
BioCyc Gene G2FUF-16901 BioCyc
Ensembl Genes ENSRNOG00000003388 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004525 ENTREZGENE
  ENSRNOT00000004525.8 UniProtKB/TrEMBL
InterPro Cenp-F UniProtKB/TrEMBL
  Centromere_CenpF_leu-rich_rpt UniProtKB/TrEMBL
  Centromere_CenpF_N UniProtKB/TrEMBL
  Centromere_CenpF_Rb-prot-bd UniProtKB/TrEMBL
NCBI Gene 257649 ENTREZGENE
PANTHER CENTROMERE PROTEIN F UniProtKB/TrEMBL
  PTHR18874 UniProtKB/TrEMBL
Pfam Cenp-F_leu_zip UniProtKB/TrEMBL
  Cenp-F_N UniProtKB/TrEMBL
  Rb-bdg_C_Cenp-F UniProtKB/TrEMBL
PhenoGen Cenpf PhenoGen
RatGTEx ENSRNOG00000003388 RatGTEx
Superfamily-SCOP Tropomyosin UniProtKB/TrEMBL
UniProt A6JGV8 ENTREZGENE, UniProtKB/TrEMBL
  E9PT83 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-25 Cenpf  centromere protein F  Cenpf  centromere autoantigen F  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Cenpf  centromere autoantigen F  Lek1  LEK/centromere protein  Symbol and Name updated 1299863 APPROVED
2003-02-27 Lek1  LEK/centromere protein      Symbol and Name status set to provisional 70820 PROVISIONAL