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Gene: Bcas1 (brain enriched myelin associated protein 1) Rattus norvegicus

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Symbol:

Bcas1

Name:

brain enriched myelin associated protein 1

RGD ID:

628644

Description:

Predicted to be involved in myelination. Located in cytoplasm. Is active in synapse. Orthologous to human BCAS1 (brain enriched myelin associated protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

band 83; Band83; breast carcinoma amplified sequence 1; breast carcinoma-amplified sequence 1 homolog; PMES-2; Pmes-2 ed; Pmes-2b; Pmes-2c; Pmes-2d; protein whose mRNA is enriched in synaptosomes 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	179,554,754 - 179,637,800 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	179,551,704 - 179,637,743 (-)	Ensembl				GRCr8
mRatBN7.2	3	159,136,077 - 159,219,072 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	159,136,083 - 159,219,106 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	162,936,261 - 163,011,272 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	171,435,535 - 171,510,911 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	169,177,129 - 169,252,136 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	167,957,994 - 168,033,462 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	167,957,994 - 168,033,457 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	174,061,259 - 174,143,949 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	161,395,062 - 161,475,655 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	157,679,729 - 157,755,458 (-)	NCBI		Celera
RGSC_v3.1	3	161,301,379 - 161,363,959 (-)	NCBI
Cytogenetic Map	3	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Familial Prostate Cancer (ISO)

Prostatic Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

chlorpyrifos (ISO)

cobalt dichloride (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

epoxiconazole (ISO)

ethanol (ISO)

flavonoids (EXP)

furan (EXP)

glycidol (EXP)

indole-3-methanol (EXP)

iron dichloride (ISO)

lithium atom (ISO)

lithium hydride (ISO)

menadione (ISO)

methoxychlor (EXP)

morphine (ISO)

N-acetyl-L-cysteine (EXP)

N-nitrosodiethylamine (EXP,ISO)

nicotine (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

pentanal (ISO)

raloxifene (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

testosterone (ISO)

titanium dioxide (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

myelination (IBA,IEA,ISO,ISS)

Cellular Component

cytoplasm (IDA,IEA)

synapse (IDA,IEP)

Molecular Function

protein binding (IPI)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Cloning and characterization of a novel synaptosome-enriched mRNA that encodes 31 kDa protein.	Ishimoto T, etal., Biochim Biophys Acta 2002 Dec 12;1579(2-3):189-95.
3.	Subcellular localization of PMES-2 proteins regulated by their two cytoskeleton-associated domains.	Ninomiya K, etal., Cell Mol Neurobiol. 2005 Aug;25(5):899-911. doi: 10.1007/s10571-005-4955-5.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:22871113	PMID:23533145	PMID:28230289

Genomics

Comparative Map Data

Bcas1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	179,554,754 - 179,637,800 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	179,551,704 - 179,637,743 (-)	Ensembl				GRCr8
mRatBN7.2	3	159,136,077 - 159,219,072 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	159,136,083 - 159,219,106 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	162,936,261 - 163,011,272 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	171,435,535 - 171,510,911 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	169,177,129 - 169,252,136 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	167,957,994 - 168,033,462 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	167,957,994 - 168,033,457 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	174,061,259 - 174,143,949 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	161,395,062 - 161,475,655 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	157,679,729 - 157,755,458 (-)	NCBI		Celera
RGSC_v3.1	3	161,301,379 - 161,363,959 (-)	NCBI
Cytogenetic Map	3	q42	NCBI

BCAS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	53,943,541 - 54,070,594 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	53,936,777 - 54,070,641 (-)	Ensembl			hg38	GRCh38
GRCh37	20	52,560,080 - 52,687,133 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	51,993,924 - 52,120,490 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	51,993,923 - 52,120,490	NCBI
Celera	20	49,264,729 - 49,391,950 (-)	NCBI		Celera
Cytogenetic Map	20	q13.2	NCBI
HuRef	20	49,306,639 - 49,433,877 (-)	NCBI		HuRef
CHM1_1	20	52,463,305 - 52,590,487 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	55,717,036 - 55,844,502 (-)	NCBI		T2T-CHM13v2.0

Bcas1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	170,188,911 - 170,270,292 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	170,188,911 - 170,269,765 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	170,343,973 - 170,427,911 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	170,346,991 - 170,427,845 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	170,172,491 - 170,253,345 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	170,038,353 - 170,119,033 (-)	NCBI		MGSCv36	mm8
Celera	2	176,300,838 - 176,381,866 (-)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	91.41	NCBI

Bcas1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	4,951,433 - 5,055,238 (+)	Ensembl
ChiLan1.0	NW_004955445	4,951,645 - 5,049,925 (+)	NCBI	ChiLan1.0	ChiLan1.0

BCAS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	59,695,796 - 59,811,187 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	59,688,917 - 59,804,308 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	50,289,582 - 50,375,287 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	51,512,049 - 51,639,255 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	51,509,978 - 51,639,255 (-)	Ensembl			panPan2	panpan1.1

BCAS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	39,702,242 - 39,799,787 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	39,699,931 - 39,800,185 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	38,948,017 - 39,045,353 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	40,414,597 - 40,512,333 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	40,408,542 - 40,512,738 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	39,650,765 - 39,748,311 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	39,786,034 - 39,883,711 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	40,368,393 - 40,466,014 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Bcas1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	186,093,188 - 186,184,931 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	1,561,848 - 1,638,722 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	1,546,833 - 1,634,269 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BCAS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	54,920,712 - 55,039,346 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	54,920,714 - 55,039,470 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	61,650,565 - 61,658,234 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	17	61,712,035 - 61,809,255 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BCAS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	9,972,244 - 10,098,126 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	9,972,433 - 10,096,747 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	58,104,958 - 58,218,708 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bcas1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624790	2,294,457 - 2,385,954 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624790	2,285,607 - 2,385,582 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Bcas1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	147,473,470 - 147,557,770 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	178
Count of miRNA genes:	140
Interacting mature miRNAs:	158
Transcripts:	ENSRNOT00000055111
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161492708	189428310	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
8552791	Vie2	Viral induced encephalitis QTL 2	4.1		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	3	166376089	189428310	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	161799270	187311134	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1598854	Memor10	Memory QTL 10	2		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	3	166376089	189428310	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	137114333	182114333	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat

Markers in Region

D3Rat136

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	179,599,159 - 179,599,374 (+)	Marker Load Pipeline
mRatBN7.2	3	159,180,483 - 159,180,698 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	168,002,025 - 168,002,239	NCBI	Rnor6.0
Rnor_5.0	3	174,105,307 - 174,105,521	UniSTS	Rnor5.0
RGSC_v3.4	3	161,441,537 - 161,441,752	RGD	RGSC3.4
RGSC_v3.4	3	161,441,538 - 161,441,752	UniSTS	RGSC3.4
Celera	3	157,723,984 - 157,724,195	UniSTS
RGSC_v3.1	3	161,347,573 - 161,347,788	RGD
SHRSP x BN Map	3	84.5699	UniSTS
SHRSP x BN Map	3	84.5699	RGD
Cytogenetic Map	3	q42	UniSTS

RH139526

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	159,136,607 - 159,136,798 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	167,958,368 - 167,958,558	NCBI	Rnor6.0
Rnor_5.0	3	174,061,634 - 174,061,824	UniSTS	Rnor5.0
RGSC_v3.4	3	161,395,436 - 161,395,626	UniSTS	RGSC3.4
Celera	3	157,680,103 - 157,680,293	UniSTS
RH 3.4 Map	3	1493.8	UniSTS
Cytogenetic Map	3	q42	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	62	156	78	77	47	67	47	6	289	160	10	136	58	89	30	10	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001415675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_145670	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB029897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB180269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB180270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB180271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB180272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC094306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC103480	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO405877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000055111 ⟹ ENSRNOP00000051984

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	179,554,754 - 179,637,743 (-)	Ensembl
mRatBN7.2 Ensembl	3	159,136,234 - 159,219,106 (-)	Ensembl
Rnor_6.0 Ensembl	3	167,957,994 - 168,033,457 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000087579 ⟹ ENSRNOP00000071338

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	179,554,754 - 179,637,743 (-)	Ensembl
mRatBN7.2 Ensembl	3	159,136,234 - 159,219,106 (-)	Ensembl
Rnor_6.0 Ensembl	3	167,958,276 - 168,018,410 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101069 ⟹ ENSRNOP00000087069

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	179,555,193 - 179,615,545 (-)	Ensembl
mRatBN7.2 Ensembl	3	159,136,516 - 159,219,106 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115742 ⟹ ENSRNOP00000094246

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	179,555,193 - 179,615,545 (-)	Ensembl
mRatBN7.2 Ensembl	3	159,136,234 - 159,219,106 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115872 ⟹ ENSRNOP00000096594

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	179,554,760 - 179,615,532 (-)	Ensembl
mRatBN7.2 Ensembl	3	159,136,083 - 159,219,106 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000126012 ⟹ ENSRNOP00000106378

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	179,551,704 - 179,616,100 (-)	Ensembl

RefSeq Acc Id:

NM_001415675 ⟹ NP_001402604

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	179,554,754 - 179,637,743 (-)	NCBI
mRatBN7.2	3	159,136,077 - 159,219,072 (-)	NCBI

RefSeq Acc Id:

NM_145670 ⟹ NP_663703

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	179,554,754 - 179,637,743 (-)	NCBI
mRatBN7.2	3	159,136,077 - 159,219,072 (-)	NCBI
Rnor_6.0	3	167,957,994 - 168,033,457 (-)	NCBI
Rnor_5.0	3	174,061,259 - 174,143,949 (-)	NCBI
RGSC_v3.4	3	161,395,062 - 161,475,655 (-)	RGD
Celera	3	157,679,729 - 157,755,458 (-)	RGD

Sequence:

show sequence

ATGGGAAACCAGATGAGCGTCCCACTAAGACCTGGAGACCAGGAGCATGACCCGGAAGCAGACA
CTTACAAGGTGACGTCGGACAACGAGTGTGTTCAGAATGGCATCCCGGTGGTGGTGTCCACTCG
TGTGATTCAACACTATGAGGAAGTCGATTTGGGAATCAACAGCTTGAAGGATAATGTGCCCGCT
TCTTCCCCCGAGACAATGGAGGCTCACGCTGTGGCTGATGCCAGCGGAAAGAATCTTGGGAAAG
GATCCAAGCCCAAAGCACCAGCTGCTAGGTCCCATTTTTTCTTGACACTCTCTCGGCCTGTACC
AGGACGTCCCGGGGACCAAGGCACAGATTCATCGGCTGCATCGGGGAGGCTTGATGTCAGCCCA
GGCACGGCGCCTGAGAACAAAGACCCGAGTGAGCACGGGGCACTTCCGGTGGCAGCTGCACCAG
GGCCGGCTCCAGATAAAACCCCAGGGTGCACTGAGGCCAAGCAGCAGACCCTCCCTGCCACCAG
CCCACTGGCACCTTCACCACCTGAGTCCCAGGCAGAAGCCCCGTCCAGGCCCAAGGATTTCAGC
TTTTTGAACAGACTCTTTAAACTGGACAAGGGAAGAGAAAGCGCGCCGGCTGACAGCCCGCCTG
AAGAAGGGAAAGGGTCCAAAAGCCAAGAACGGGCCATAGAGGCTCCTGCTGTACCAGGGAATCC
TCATGGTGTCTCTGCAGGGAAGGACATAGTGGACAGCGAGGAGAGAAAGCAAGAAGTTGACACT
CTGAGTTATTCTGTCCCTGCGGATCCAGAGGTGCTGGGGACCACGAAGGAGGACCCCCAGGTGG
TAGACGCCACAGAGAATAGTAATTCCATCATGAGCTTCTTCAAGACACTAGTTTCGCCTAACAA
AACTGAAACAAAGAAGGACCCAGAAGACACGGACGCCGAGAATTCACCCACTACTCCAGCCAAT
CTCAAGTCGGACAAAGCCGACCTCACCCCCCAGGAGACCCAAGGGACAGCCAAGAGTTCCAAGG
GCAGCAGTCAGCCAGGCCAGGCGCCATCTGCGGGAACCAGCGACACAGCAAGAGAGGGTGGCAA
GGAGAAGGCGGGGCCCACCTCCTTACCACTGGGAAAGCTGTTTTGGAAGAAGTCAGTTAAGGAG
GATTCACTTTCCACAGGCGCAGAGGAGAACGCGGTGTGTGAGCCACCAGTAGAGACTGTAAGGC
TTGAGGAAGTAGAATCCACCTTACAAACCGTGGATCTCACTGAGAAAGAAACCCAGACTGAGCC
CACAGATGTGAAAGTCAAAGAAGAAAGCAAACCCCGGAGGACCCCTCTGATGGCGTTTCTCAGA
CAAATGTCAGTGAGAGGGAGCGAAGGGATCACCCGCTCGGAAGAGAGTAACGGGAAAGACTCCA
GCTGCCAAACATCAAACTCCACGGAGAAGACGCCCTCACCCCCAGAGCCGGAGCCCGCGGGGAC
AGCCCAGAAAAACAAAGAGACCTCCTCGAAGGACAAGAAGTCGGTGGACAAGAAGTCAGCGGCT
GAGAGCAACAAGCAGAAGAATGGCAAACCGGAAGCCAGAGAACCAGCGCCGTGTGTGCAGCAGC
CCACGGTGGAGGTGAACGCGCTGCAGACTGGGGACAAGACCCCAAAGAGGTCTGAGAAGCGGCG
ACAGTCCCTCGGGGGCTTTCTGAAGGGCCTGGGACCAAAGCGGATGTTGGATGCTCAAGTGCAA
ACGGACCCCGTATCCATCGGACCAGTTGGAAAATCCAAGTAAACAAATCACCTAGCTCCCACCA
GGTTCTCCTCCCACTCCATCTCCTGTCTAGACCCACACCGTGTATATATATATATTTTTTTTTT
CTTCTGGCCAGCCAATGAAATTCTGCCTGAATTGTTGTAGATCAAGGTGTATTATTTATGACTC
TGGTCCAGTCTTTCCTGGCATATAAGTGTATAAATGGGTTAGCAGGTTAACCAGTTGATCTAGG
GGAGCAGGTGAGTGCCAGGGTGGGAGGAAGTAAGTAGATAAAGGCATTTGTGTTAAGTTATGAA
AAAAAATGGCAGGTATCCAGTAAGGTGCAGAAGAAAAGTGCTTAGGAGAAAAAGAATATCCGGC
TCTGTAGCCAGTGTTGCTGTACGCTCTGAACCTGAAGAGGGGAAGGGAAGACTGGCTTAGTTCA
TTTCACATTTGGGGGAAGGAGGACTCAGGGCAGGCTCTACGTTGGGCACCTGCCAACTTTTGGA
ATAGAATGTGTGGGCTATAAAAGAATTGGTTTTCAAATAGGGTCCTTGAAAGTTATCGGTGATG
GGGAAGTGATTCGCTGAGGAGGGCTCACAGTGATTTGGGGGAACAATTACTTCTGAGGCACAGG
GACAAGGGCATGAATTACCAACTTCAAAAGAAAAAAAAAACGGCAAAATGAAAGTTGCAGGTTC
GTTTTGCGACACAAGGGGGCGCCAAGACCTCCGCTTTCCCCTTTGCATCCGGTACCCCTAACAA
AGATTTGTTTCTGTAATATTTCGTTATTAATGTTTCTCAGATGGCTGAGGGACTTGCTTCATCT
GTTCCGTCTGACGCTTATCTCACGCCTGTCTGTAATATCCTAATGTTTTCATAATGTGCTCTGA
TAAAAACCCTCCCCTAACCCAGTTAATAAAAATTGACAGATTATGCAAATA

hide sequence

RefSeq Acc Id:

XM_063283092 ⟹ XP_063139162

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	179,554,911 - 179,637,791 (-)	NCBI

RefSeq Acc Id:

XM_063283093 ⟹ XP_063139163

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	179,554,911 - 179,637,791 (-)	NCBI

RefSeq Acc Id:

XM_063283094 ⟹ XP_063139164

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	179,554,911 - 179,637,800 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001402604	(Get FASTA)	NCBI Sequence Viewer
	NP_663703	(Get FASTA)	NCBI Sequence Viewer
	XP_063139162	(Get FASTA)	NCBI Sequence Viewer
	XP_063139163	(Get FASTA)	NCBI Sequence Viewer
	XP_063139164	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH94306	(Get FASTA)	NCBI Sequence Viewer
	AAI03481	(Get FASTA)	NCBI Sequence Viewer
	BAC01271	(Get FASTA)	NCBI Sequence Viewer
	BAD69785	(Get FASTA)	NCBI Sequence Viewer
	BAD69786	(Get FASTA)	NCBI Sequence Viewer
	BAD69787	(Get FASTA)	NCBI Sequence Viewer
	BAD69788	(Get FASTA)	NCBI Sequence Viewer
	EDL96334	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000051984
	ENSRNOP00000051984.2
	ENSRNOP00000071338
	ENSRNOP00000094246.1
GenBank Protein	Q3ZB98	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_663703 ⟸ NM_145670
- Peptide Label:	isoform 2
- UniProtKB:	Q5TLH1 (UniProtKB/Swiss-Prot), Q5TLH0 (UniProtKB/Swiss-Prot), Q5TLG9 (UniProtKB/Swiss-Prot), Q5TLG8 (UniProtKB/Swiss-Prot), Q52KK0 (UniProtKB/Swiss-Prot), Q3ZB98 (UniProtKB/Swiss-Prot), Q8K4U9 (UniProtKB/Swiss-Prot), F1LN49 (UniProtKB/TrEMBL), A0A8I6AQA4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNQMSVPLRPGDQEHDPEADTYKVTSDNECVQNGIPVVVSTRVIQHYEEVDLGINSLKDNVPA SSPETMEAHAVADASGKNLGKGSKPKAPAARSHFFLTLSRPVPGRPGDQGTDSSAASGRLDVSP GTAPENKDPSEHGALPVAAAPGPAPDKTPGCTEAKQQTLPATSPLAPSPPESQAEAPSRPKDFS FLNRLFKLDKGRESAPADSPPEEGKGSKSQERAIEAPAVPGNPHGVSAGKDIVDSEERKQEVDT LSYSVPADPEVLGTTKEDPQVVDATENSNSIMSFFKTLVSPNKTETKKDPEDTDAENSPTTPAN LKSDKADLTPQETQGTAKSSKGSSQPGQAPSAGTSDTAREGGKEKAGPTSLPLGKLFWKKSVKE DSLSTGAEENAVCEPPVETVRLEEVESTLQTVDLTEKETQTEPTDVKVKEESKPRRTPLMAFLR QMSVRGSEGITRSEESNGKDSSCQTSNSTEKTPSPPEPEPAGTAQKNKETSSKDKKSVDKKSAA ESNKQKNGKPEAREPAPCVQQPTVEVNALQTGDKTPKRSEKRRQSLGGFLKGLGPKRMLDAQVQ TDPVSIGPVGKSK hide sequence

Ensembl Acc Id:

ENSRNOP00000051984 ⟸ ENSRNOT00000055111

Ensembl Acc Id:

ENSRNOP00000071338 ⟸ ENSRNOT00000087579

Ensembl Acc Id:

ENSRNOP00000096594 ⟸ ENSRNOT00000115872

Ensembl Acc Id:

ENSRNOP00000094246 ⟸ ENSRNOT00000115742

Ensembl Acc Id:

ENSRNOP00000087069 ⟸ ENSRNOT00000101069

RefSeq Acc Id:	NP_001402604 ⟸ NM_001415675
- Peptide Label:	isoform 1
- UniProtKB:	A0A0G2K079 (UniProtKB/TrEMBL), A6JXS4 (UniProtKB/TrEMBL), A0A8I6AQA4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063139164 ⟸ XM_063283094
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6A7B6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063139163 ⟸ XM_063283093
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AQA4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063139162 ⟸ XM_063283092
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AQA4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000106378 ⟸ ENSRNOT00000126012

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q3ZB98-F1-model_v2	AlphaFold	Q3ZB98	1-589	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692705

Promoter ID:

EPDNEW_R3225

Type:

single initiation site

Name:

Bcas1_1

Description:

breast carcinoma amplified sequence 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	168,018,411 - 168,018,471	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628644	AgrOrtholog
BioCyc Gene	G2FUF-46620	BioCyc
Ensembl Genes	ENSRNOG00000012906	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000055111	ENTREZGENE
	ENSRNOT00000055111.4	UniProtKB/Swiss-Prot
	ENSRNOT00000087579	ENTREZGENE
	ENSRNOT00000115742.1	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7313637	IMAGE-MGC_LOAD
	IMAGE:7939378	IMAGE-MGC_LOAD
InterPro	NABC1	UniProtKB/Swiss-Prot
KEGG Report	rno:246755	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105313	IMAGE-MGC_LOAD
	MGC:124561	IMAGE-MGC_LOAD
NCBI Gene	246755	ENTREZGENE
PANTHER	BREAST CARCINOMA-AMPLIFIED SEQUENCE 1	UniProtKB/Swiss-Prot
	PTHR15016	UniProtKB/Swiss-Prot
PhenoGen	Bcas1	PhenoGen
RatGTEx	ENSRNOG00000012906	RatGTEx
UniProt	A0A0G2K079	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A7B6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AQA4	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LVS3_RAT	UniProtKB/TrEMBL
	A6JXS4	ENTREZGENE, UniProtKB/TrEMBL
	BCAS1_RAT	UniProtKB/Swiss-Prot
	F1LN49	ENTREZGENE
	Q3ZB98	ENTREZGENE
	Q52KK0	ENTREZGENE
	Q5TLG8	ENTREZGENE
	Q5TLG9	ENTREZGENE
	Q5TLH0	ENTREZGENE
	Q5TLH1	ENTREZGENE
	Q8K4U9	ENTREZGENE
UniProt Secondary	F1LN49	UniProtKB/Swiss-Prot
	Q52KK0	UniProtKB/Swiss-Prot
	Q5TLG8	UniProtKB/Swiss-Prot
	Q5TLG9	UniProtKB/Swiss-Prot
	Q5TLH0	UniProtKB/Swiss-Prot
	Q5TLH1	UniProtKB/Swiss-Prot
	Q8K4U9	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-04-28	Bcas1	brain enriched myelin associated protein 1	Bcas1	breast carcinoma amplified sequence 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Bcas1	breast carcinoma amplified sequence 1	Band83	band 83	Symbol and Name updated	1299863	APPROVED
2003-02-27	Band83	band 83			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized in the postsynaptic density	632030
gene_expression	expressed only in brain, abundant in the dendrites of the hippocampal neurons	632030
gene_protein	31 kDa	632030

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD