Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rnf34 | Rat | (+)-catechin | multiple interactions | ISO | RNF34 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of RNF34 mRNA | CTD | PMID:24763279 | Rnf34 | Rat | (-)-demecolcine | increases expression | ISO | RNF34 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of RNF34 mRNA | CTD | PMID:23649840 | Rnf34 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Rnf34 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RNF34 mRNA | CTD | PMID:22206623 | Rnf34 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Rnf34 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of RNF34 mRNA | CTD | PMID:22206623 | Rnf34 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rnf34 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RNF34 mRNA | CTD | PMID:21570461 | Rnf34 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of RNF34 mRNA | CTD | PMID:21346803 | Rnf34 | Rat | 5-fluorouracil | multiple interactions | ISO | RNF34 (Homo sapiens) | 6480464 | [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA; [Fluorouracil co-treated with more ... | CTD | PMID:16080519|PMID:16407826|PMID:16596200 | Rnf34 | Rat | 5-fluorouracil | decreases response to substance | ISO | RNF34 (Homo sapiens) | 6480464 | RNF34 protein results in decreased susceptibility to Fluorouracil; RNF34 protein results in decreased susceptibility to more ... | CTD | PMID:16080519|PMID:16270526|PMID:16407826 | Rnf34 | Rat | aflatoxin B1 | increases expression | ISO | Rnf34 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of RNF34 mRNA | CTD | PMID:19770486 | Rnf34 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of RNF34 mRNA | CTD | PMID:16483693 | Rnf34 | Rat | arsane | affects methylation | ISO | RNF34 (Homo sapiens) | 6480464 | Arsenic affects the methylation of RNF34 gene | CTD | PMID:25304211 | Rnf34 | Rat | arsenic atom | affects methylation | ISO | RNF34 (Homo sapiens) | 6480464 | Arsenic affects the methylation of RNF34 gene | CTD | PMID:25304211 | Rnf34 | Rat | arsenous acid | increases expression | ISO | RNF34 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of RNF34 mRNA | CTD | PMID:20458559 | Rnf34 | Rat | benzo[a]pyrene | multiple interactions | ISO | Rnf34 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RNF34 mRNA] | CTD | PMID:22228805 | Rnf34 | Rat | beta-lapachone | decreases expression | ISO | RNF34 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of RNF34 mRNA | CTD | PMID:38218311 | Rnf34 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Rnf34 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of RNF34 mRNA | CTD | PMID:34319233 | Rnf34 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RNF34 mRNA | CTD | PMID:25181051 | Rnf34 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of RNF34 gene | CTD | PMID:28505145 | Rnf34 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RNF34 mRNA | CTD | PMID:30816183|PMID:32528016 | Rnf34 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of RNF34 mRNA | CTD | PMID:33453195 | Rnf34 | Rat | cadmium dichloride | decreases expression | ISO | RNF34 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of RNF34 mRNA | CTD | PMID:38568856 | Rnf34 | Rat | chlorpyrifos | increases expression | ISO | Rnf34 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of RNF34 mRNA | CTD | PMID:37019170 | Rnf34 | Rat | choline | multiple interactions | ISO | Rnf34 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Rnf34 | Rat | cisplatin | multiple interactions | ISO | RNF34 (Homo sapiens) | 6480464 | RNF34 protein inhibits the reaction [Cisplatin results in increased activity of CASP3 protein] | CTD | PMID:16080519 | Rnf34 | Rat | cisplatin | decreases response to substance | ISO | RNF34 (Homo sapiens) | 6480464 | RNF34 protein results in decreased susceptibility to Cisplatin | CTD | PMID:16080519 | Rnf34 | Rat | copper(II) sulfate | decreases expression | ISO | RNF34 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of RNF34 mRNA | CTD | PMID:19549813 | Rnf34 | Rat | crocidolite asbestos | decreases expression | ISO | Rnf34 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of RNF34 mRNA | CTD | PMID:29279043 | Rnf34 | Rat | diarsenic trioxide | increases expression | ISO | RNF34 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of RNF34 mRNA | CTD | PMID:20458559 | Rnf34 | Rat | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of RNF34 mRNA | CTD | PMID:22546817 | Rnf34 | Rat | Dibutyl phosphate | affects expression | ISO | RNF34 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of RNF34 mRNA | CTD | PMID:37042841 | Rnf34 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of RNF34 mRNA | CTD | PMID:21266533 | Rnf34 | Rat | dibutyl phthalate | decreases expression | ISO | Rnf34 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of RNF34 mRNA | CTD | PMID:17361019|PMID:21266533 | Rnf34 | Rat | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of RNF34 mRNA | CTD | PMID:22546817 | Rnf34 | Rat | epoxiconazole | decreases expression | ISO | Rnf34 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of RNF34 mRNA | CTD | PMID:35436446 | Rnf34 | Rat | folic acid | multiple interactions | ISO | Rnf34 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RNF34 mRNA; [Methionine deficiency co-treated more ... | CTD | PMID:20938992|PMID:22206623 | Rnf34 | Rat | FR900359 | increases phosphorylation | ISO | RNF34 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of RNF34 protein | CTD | PMID:37730182 | Rnf34 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of RNF34 gene | CTD | PMID:22079235 | Rnf34 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of RNF34 mRNA | CTD | PMID:33387578 | Rnf34 | Rat | irinotecan | multiple interactions | ISO | RNF34 (Homo sapiens) | 6480464 | RNF34 protein inhibits the reaction [Irinotecan results in increased activity of CASP3 protein] | CTD | PMID:16080519 | Rnf34 | Rat | irinotecan | decreases response to substance | ISO | RNF34 (Homo sapiens) | 6480464 | RNF34 protein results in decreased susceptibility to Irinotecan | CTD | PMID:16080519 | Rnf34 | Rat | isoflurane | decreases methylation | ISO | Rnf34 (Mus musculus) | 6480464 | Isoflurane results in decreased methylation of RNF34 mRNA | CTD | PMID:35249202 | Rnf34 | Rat | L-methionine | multiple interactions | ISO | Rnf34 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Rnf34 | Rat | leflunomide | decreases expression | ISO | RNF34 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of RNF34 mRNA | CTD | PMID:28988120 | Rnf34 | Rat | nickel atom | increases expression | ISO | RNF34 (Homo sapiens) | 6480464 | Nickel results in increased expression of RNF34 mRNA | CTD | PMID:25583101 | Rnf34 | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of RNF34 mRNA | CTD | PMID:22546817 | Rnf34 | Rat | paracetamol | affects expression | ISO | Rnf34 (Mus musculus) | 6480464 | Acetaminophen affects the expression of RNF34 mRNA | CTD | PMID:17562736 | Rnf34 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of RNF34 mRNA | CTD | PMID:33387578 | Rnf34 | Rat | paracetamol | increases expression | ISO | RNF34 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of RNF34 mRNA | CTD | PMID:22230336 | Rnf34 | Rat | PhIP | decreases expression | ISO | RNF34 (Homo sapiens) | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RNF34 mRNA | CTD | PMID:20816883 | Rnf34 | Rat | quercetin | decreases phosphorylation | ISO | RNF34 (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of RNF34 protein | CTD | PMID:35688186 | Rnf34 | Rat | resveratrol | multiple interactions | ISO | RNF34 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of RNF34 mRNA | CTD | PMID:23557933 | Rnf34 | Rat | sevoflurane | decreases methylation | ISO | Rnf34 (Mus musculus) | 6480464 | Sevoflurane results in decreased methylation of RNF34 mRNA | CTD | PMID:35249202 | Rnf34 | Rat | sodium arsenite | decreases expression | ISO | RNF34 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of RNF34 mRNA | CTD | PMID:38568856 | Rnf34 | Rat | titanium dioxide | decreases methylation | ISO | Rnf34 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of RNF34 gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Rnf34 | Rat | triptonide | increases expression | ISO | Rnf34 (Mus musculus) | 6480464 | triptonide results in increased expression of RNF34 mRNA | CTD | PMID:33045310 | Rnf34 | Rat | valproic acid | decreases expression | ISO | RNF34 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of RNF34 mRNA | CTD | PMID:29154799 | Rnf34 | Rat | valproic acid | affects expression | ISO | Rnf34 (Mus musculus) | 6480464 | Valproic Acid affects the expression of RNF34 mRNA | CTD | PMID:17963808 | Rnf34 | Rat | valproic acid | affects expression | ISO | RNF34 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RNF34 mRNA | CTD | PMID:25979313 | Rnf34 | Rat | vincristine | increases expression | ISO | RNF34 (Homo sapiens) | 6480464 | Vincristine results in increased expression of RNF34 mRNA | CTD 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