Adgrg1 (adhesion G protein-coupled receptor G1) - Rat Genome Database

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Gene: Adgrg1 (adhesion G protein-coupled receptor G1) Rattus norvegicus
Analyze
Symbol: Adgrg1
Name: adhesion G protein-coupled receptor G1
RGD ID: 628617
Description: Predicted to enable several functions, including collagen binding activity; heparin binding activity; and phosphatidylserine binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; gliogenesis; and positive regulation of signal transduction. Predicted to act upstream of or within cerebral cortex regionalization; hematopoietic stem cell homeostasis; and positive regulation of neural precursor cell proliferation. Predicted to be located in glial limiting end-foot. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in bilateral frontoparietal polymicrogyria and bilateral perisylvian polymicrogyria. Orthologous to human ADGRG1 (adhesion G protein-coupled receptor G1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adhesion G-protein coupled receptor G1; G protein-coupled receptor 56; G-protein coupled receptor 56; Gpr56; LOC102554158; uncharacterized LOC102554158
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81910,009,983 - 10,047,138 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1910,010,031 - 10,047,124 (-)EnsemblGRCr8
mRatBN7.21910,003,963 - 10,041,122 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1910,003,975 - 10,041,108 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx199,968,201 - 10,005,273 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,735,039 - 10,772,116 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01910,021,858 - 10,058,994 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,423,534 - 10,460,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,423,501 - 10,460,674 (-)Ensemblrn6Rnor6.0
Rnor_5.01910,403,001 - 10,442,286 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41910,438,332 - 10,475,607 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera199,891,471 - 9,928,021 (-)NCBICelera
RGSC_v3.11910,443,185 - 10,480,433 (-)NCBI
Cytogenetic Map19p13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atazanavir sulfate  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
Butylbenzyl phthalate  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
cortisol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
Dibutyl phosphate  (ISO)
dimethylarsinic acid  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
enzacamene  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fipronil  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
GSK-J4  (ISO)
hydrazine  (ISO)
inulin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isobutanol  (ISO)
Lasiocarpine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
mifepristone  (ISO)
mitomycin C  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N(4)-hydroxycytidine  (ISO)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
naled  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nitrates  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
quercitrin  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sulforaphane  (ISO)
Sunset Yellow FCF  (ISO)
tamoxifen  (ISO)
tartrazine  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
trametinib  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vitamin D  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GPR56, a novel secretin-like human G-protein-coupled receptor gene. Liu M, etal., Genomics 1999 Feb 1;55(3):296-305.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15044805   PMID:16757564   PMID:17945200   PMID:18509043   PMID:20981830   PMID:21349848   PMID:21708946   PMID:21724588   PMID:21768377   PMID:22871113   PMID:23376485   PMID:23533145  
PMID:24531968   PMID:27068534   PMID:31304602  


Genomics

Comparative Map Data
Adgrg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81910,009,983 - 10,047,138 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1910,010,031 - 10,047,124 (-)EnsemblGRCr8
mRatBN7.21910,003,963 - 10,041,122 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1910,003,975 - 10,041,108 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx199,968,201 - 10,005,273 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,735,039 - 10,772,116 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01910,021,858 - 10,058,994 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,423,534 - 10,460,674 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,423,501 - 10,460,674 (-)Ensemblrn6Rnor6.0
Rnor_5.01910,403,001 - 10,442,286 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41910,438,332 - 10,475,607 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera199,891,471 - 9,928,021 (-)NCBICelera
RGSC_v3.11910,443,185 - 10,480,433 (-)NCBI
Cytogenetic Map19p13NCBI
ADGRG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381657,619,738 - 57,665,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1657,610,652 - 57,665,580 (+)Ensemblhg38GRCh38
GRCh371657,653,650 - 57,699,479 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361656,211,459 - 56,256,445 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341656,220,022 - 56,256,438NCBI
Celera1642,155,129 - 42,200,163 (+)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1643,521,500 - 43,566,585 (+)NCBIHuRef
CHM1_11659,061,969 - 59,107,000 (+)NCBICHM1_1
T2T-CHM13v2.01663,414,941 - 63,460,767 (+)NCBIT2T-CHM13v2.0
Adgrg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,701,321 - 95,740,836 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl895,701,379 - 95,740,845 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38894,974,756 - 95,014,208 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl894,974,751 - 95,014,217 (+)Ensemblmm10GRCm38
MGSCv37897,508,503 - 97,538,091 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36897,873,732 - 97,903,320 (+)NCBIMGSCv36mm8
Celera899,309,115 - 99,341,094 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map847.12NCBI
Adgrg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,259,720 - 15,289,151 (+)Ensembl
ChiLan1.0NW_00495543315,253,196 - 15,288,982 (+)NCBIChiLan1.0ChiLan1.0
ADGRG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,090,347 - 67,136,251 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,011,226 - 73,057,121 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01637,896,177 - 37,942,040 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,027,946 - 57,074,221 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,036,425 - 57,074,221 (+)EnsemblpanPan2panpan1.1
ADGRG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,805,737 - 58,842,618 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,805,834 - 58,852,684 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha255,435,490 - 55,472,410 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0259,344,120 - 59,381,257 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl259,344,129 - 59,381,633 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1256,175,783 - 56,212,651 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0257,183,275 - 57,220,434 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0258,076,631 - 58,113,771 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Adgrg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934949,905,813 - 49,935,816 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364759,671,868 - 9,681,988 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364759,653,233 - 9,683,258 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl619,527,648 - 19,570,893 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1619,523,618 - 19,570,891 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,648,674 - 17,671,453 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,559,792 - 43,595,906 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl543,570,189 - 43,596,087 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604732,602,512 - 32,646,023 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgrg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474628,436,895 - 28,476,926 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474628,439,855 - 28,476,551 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Adgrg1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1171,853,886 - 1,890,792 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Adgrg1
284 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:74
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000020921
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131969901Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124694445Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127361636Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
AI412938  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21910,004,184 - 10,004,323 (+)MAPPERmRatBN7.2
Rnor_6.01910,423,756 - 10,423,894NCBIRnor6.0
Rnor_5.01910,403,223 - 10,403,361UniSTSRnor5.0
RGSC_v3.41910,438,554 - 10,438,692UniSTSRGSC3.4
Celera199,891,693 - 9,891,831UniSTS
RH 3.4 Map1995.01UniSTS
Cytogenetic Map19p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 90 59 6 354 190 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_152242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC106681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF529886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB766806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK482497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO557428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV116515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EX488169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000020921   ⟹   ENSRNOP00000020921
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1910,010,031 - 10,047,124 (-)Ensembl
mRatBN7.2 Ensembl1910,004,011 - 10,041,108 (-)Ensembl
Rnor_6.0 Ensembl1910,423,582 - 10,460,674 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081223   ⟹   ENSRNOP00000072630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1910,423,542 - 10,460,674 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000088048   ⟹   ENSRNOP00000071610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1910,010,031 - 10,040,258 (-)Ensembl
mRatBN7.2 Ensembl1910,003,975 - 10,034,234 (-)Ensembl
Rnor_6.0 Ensembl1910,423,501 - 10,450,186 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000134765   ⟹   ENSRNOP00000106989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1910,010,031 - 10,040,258 (-)Ensembl
RefSeq Acc Id: NM_152242   ⟹   NP_689448
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,009,983 - 10,047,138 (-)NCBI
mRatBN7.21910,003,963 - 10,041,122 (-)NCBI
Rnor_6.01910,423,534 - 10,460,674 (-)NCBI
Rnor_5.01910,403,001 - 10,442,286 (-)NCBI
RGSC_v3.41910,438,332 - 10,475,607 (-)RGD
Celera199,891,471 - 9,928,021 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772264   ⟹   XP_008770486
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,009,986 - 10,044,975 (-)NCBI
mRatBN7.21910,003,963 - 10,034,338 (-)NCBI
Rnor_6.01910,423,534 - 10,456,145 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772267   ⟹   XP_008770489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,009,986 - 10,029,517 (-)NCBI
mRatBN7.21910,003,963 - 10,023,490 (-)NCBI
Rnor_6.01910,423,534 - 10,443,050 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772270   ⟹   XP_008770492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,009,986 - 10,029,686 (-)NCBI
mRatBN7.21910,003,963 - 10,023,662 (-)NCBI
Rnor_6.01910,423,534 - 10,444,900 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097527   ⟹   XP_038953455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,009,986 - 10,028,290 (-)NCBI
mRatBN7.21910,003,963 - 10,022,277 (-)NCBI
RefSeq Acc Id: XM_039097528   ⟹   XP_038953456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,009,986 - 10,024,553 (-)NCBI
mRatBN7.21910,003,963 - 10,018,543 (-)NCBI
RefSeq Acc Id: XM_063277826   ⟹   XP_063133896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,009,986 - 10,040,355 (-)NCBI
RefSeq Acc Id: XM_063277827   ⟹   XP_063133897
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81910,009,986 - 10,021,973 (-)NCBI
RefSeq Acc Id: NP_689448   ⟸   NM_152242
- Peptide Label: precursor
- UniProtKB: Q8K3V3 (UniProtKB/Swiss-Prot),   A0A0G2JSP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770486   ⟸   XM_008772264
- Peptide Label: isoform X2
- UniProtKB: Q8K3V3 (UniProtKB/Swiss-Prot),   F1LMW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770492   ⟸   XM_008772270
- Peptide Label: isoform X3
- UniProtKB: Q8K3V3 (UniProtKB/Swiss-Prot),   A0A0G2JSP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770489   ⟸   XM_008772267
- Peptide Label: isoform X3
- UniProtKB: Q8K3V3 (UniProtKB/Swiss-Prot),   A0A0G2JSP0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020921   ⟸   ENSRNOT00000020921
Ensembl Acc Id: ENSRNOP00000072630   ⟸   ENSRNOT00000081223
Ensembl Acc Id: ENSRNOP00000071610   ⟸   ENSRNOT00000088048
RefSeq Acc Id: XP_038953455   ⟸   XM_039097527
- Peptide Label: isoform X3
- UniProtKB: Q8K3V3 (UniProtKB/Swiss-Prot),   A0A0G2JSP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953456   ⟸   XM_039097528
- Peptide Label: isoform X3
- UniProtKB: Q8K3V3 (UniProtKB/Swiss-Prot),   A0A0G2JSP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133896   ⟸   XM_063277826
- Peptide Label: isoform X1
- UniProtKB: Q8K3V3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063133897   ⟸   XM_063277827
- Peptide Label: isoform X3
- UniProtKB: Q8K3V3 (UniProtKB/Swiss-Prot),   A0A0G2JSP0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106989   ⟸   ENSRNOT00000134765
Protein Domains
G-protein coupled receptors family 2 profile   GAIN-B

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K3V3-F1-model_v2 AlphaFold Q8K3V3 1-687 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700935
Promoter ID:EPDNEW_R11459
Type:multiple initiation site
Name:Adgrg1_1
Description:adhesion G protein-coupled receptor G1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01910,460,480 - 10,460,540EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628617 AgrOrtholog
BioCyc Gene G2FUF-6521 BioCyc
Ensembl Genes ENSRNOG00000014963 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000020921 ENTREZGENE
  ENSRNOT00000088048 ENTREZGENE
  ENSRNOT00000134765 ENTREZGENE
Gene3D-CATH 2.60.220.50 UniProtKB/Swiss-Prot
  Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GAIN_A UniProtKB/Swiss-Prot
  GAIN_B UniProtKB/Swiss-Prot
  GAIN_dom_sf UniProtKB/Swiss-Prot
  GPCR_2-like UniProtKB/Swiss-Prot
  GPCR_2_secretin-like UniProtKB/Swiss-Prot
  GPR1/GPR3/GPR5 UniProtKB/Swiss-Prot
  GPS UniProtKB/Swiss-Prot
  PLL UniProtKB/Swiss-Prot
NCBI Gene 260326 ENTREZGENE
PANTHER ADHESION G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot
  ADHESION G-PROTEIN COUPLED RECEPTOR G1 UniProtKB/Swiss-Prot
Pfam 7tm_2 UniProtKB/Swiss-Prot
  GAIN_A UniProtKB/Swiss-Prot
  GPS UniProtKB/Swiss-Prot
  PLL UniProtKB/Swiss-Prot
PhenoGen Adgrg1 PhenoGen
PRINTS GPCRSECRETIN UniProtKB/Swiss-Prot
  GPR56ORPHANR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot
  GPS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014963 RatGTEx
SMART GPS UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A0A0G2JSP0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LPZ5_RAT UniProtKB/TrEMBL
  AGRG1_RAT UniProtKB/Swiss-Prot
  F1LMW3 ENTREZGENE, UniProtKB/TrEMBL
  Q8K3V3 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Adgrg1  adhesion G protein-coupled receptor G1  LOC102554158  uncharacterized LOC102554158  Data merged from RGD:7523177 737654 PROVISIONAL
2015-03-16 Adgrg1  adhesion G protein-coupled receptor G1  Gpr56  G protein-coupled receptor 56  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102554158  uncharacterized LOC102554158      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Gpr56  G protein-coupled receptor 56      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Gpr56  G protein-coupled receptor 56      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in heart and brain, with high level of expression in the hippocampus and hypothalamic nuclei 708336
gene_homology has similarity to class B secretin-like G-protein coupled receptors 708336