Cdk11b (cyclin-dependent kinase 11B) - Rat Genome Database

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Pathways
Gene: Cdk11b (cyclin-dependent kinase 11B) Rattus norvegicus
Analyze
Symbol: Cdk11b
Name: cyclin-dependent kinase 11B
RGD ID: 628604
Description: Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in regulation of cell growth and regulation of mRNA processing. Predicted to act upstream of or within blastocyst development; negative regulation of apoptotic signaling pathway; and regulation of mitotic nuclear division. Predicted to be located in nuclear membrane and perinuclear region of cytoplasm. Predicted to be active in nucleus. Orthologous to several human genes including CDK11B (cyclin dependent kinase 11B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cdc2l1; Cdk11; cell division cycle 2 homolog (S.pombe)-like 1; cell division cycle 2 homolog-like 1; cell division cycle 2-like protein kinase 1; cell division protein kinase 11; cyclin-dependent kinase 11; galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase CDC2L1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,495,042 - 171,521,143 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5171,495,776 - 171,521,145 (+)EnsemblGRCr8
mRatBN7.25166,212,761 - 166,238,883 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,212,829 - 166,238,876 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5168,917,908 - 168,943,888 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,739,324 - 170,765,307 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,701,863 - 170,727,846 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,051,900 - 173,078,049 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,052,063 - 173,078,046 (+)Ensemblrn6Rnor6.0
Rnor_5.05176,527,409 - 176,553,763 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45172,459,111 - 172,486,012 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5164,414,228 - 164,439,806 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Characterization of the synthesis and expression of the GTA-kinase from transformed and normal rodent cells. Kerr M, etal., Biochim Biophys Acta 1994 Aug 2;1218(3):375-87.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Protein expression pattern of CDK11(p58) during testicular development in the mouse. Niu Z, etal., Mol Cell Biochem 2005 Feb;270(1-2):99-106.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8195233   PMID:8889548   PMID:10882096   PMID:12501247   PMID:15060143   PMID:22527143   PMID:22681889   PMID:23703121  


Genomics

Comparative Map Data
Cdk11b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,495,042 - 171,521,143 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5171,495,776 - 171,521,145 (+)EnsemblGRCr8
mRatBN7.25166,212,761 - 166,238,883 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,212,829 - 166,238,876 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5168,917,908 - 168,943,888 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,739,324 - 170,765,307 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,701,863 - 170,727,846 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,051,900 - 173,078,049 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,052,063 - 173,078,046 (+)Ensemblrn6Rnor6.0
Rnor_5.05176,527,409 - 176,553,763 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45172,459,111 - 172,486,012 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5164,414,228 - 164,439,806 (+)NCBICelera
Cytogenetic Map5q36NCBI
CDK11B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,635,225 - 1,659,004 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,635,225 - 1,659,234 (-)Ensemblhg38GRCh38
GRCh3711,570,603 - 1,590,465 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,624,180 - 1,645,637 (-)NCBIBuild 36Build 36hg18NCBI36
Cytogenetic Map1p36.33NCBI
HuRef1839,060 - 867,349 (-)NCBIHuRef
CHM1_111,558,156 - 1,577,529 (-)NCBICHM1_1
T2T-CHM13v2.011,069,728 - 1,093,685 (-)NCBIT2T-CHM13v2.0
Cdk11b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,709,303 - 155,734,392 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,709,311 - 155,734,395 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384155,624,841 - 155,649,935 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,624,854 - 155,649,938 (+)Ensemblmm10GRCm38
MGSCv374154,998,978 - 155,024,041 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364154,468,669 - 154,493,732 (+)NCBIMGSCv36mm8
Celera4157,899,879 - 157,924,805 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map486.73NCBI
Cdk11b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,251,242 - 9,270,218 (+)Ensembl
ChiLan1.0NW_0049554869,251,242 - 9,270,218 (+)NCBIChiLan1.0ChiLan1.0
CDK11B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,558,305 - 226,581,539 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,214,256 - 225,237,485 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01399,997 - 423,094 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111,557,887 - 1,567,942 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,558,423 - 1,579,305 (-)EnsemblpanPan2panpan1.1
CDK11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,698,267 - 56,714,075 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,773,892 - 56,789,740 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0556,900,241 - 56,916,116 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,900,247 - 56,916,079 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,891,042 - 56,906,886 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,783,340 - 56,799,187 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0557,173,307 - 57,189,184 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CDK11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1663,804,914 - 63,819,960 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,234,564 - 58,249,513 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDK11B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120129,848,297 - 129,873,287 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605434,303,072 - 34,328,300 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:154
Count of miRNA genes:116
Interacting mature miRNAs:131
Transcripts:ENSRNOT00000050188
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5160071170172129029Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat

Markers in Region
RH131250  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,210,707 - 166,210,901 (+)MAPPERmRatBN7.2
Rnor_6.05173,049,881 - 173,050,074NCBIRnor6.0
Rnor_5.05176,525,368 - 176,525,561UniSTSRnor5.0
RGSC_v3.45172,457,564 - 172,457,757UniSTSRGSC3.4
Celera5164,412,045 - 164,412,238UniSTS
RH 3.4 Map51143.8UniSTS
Cytogenetic Map5q36UniSTS
RH134324  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,238,039 - 166,238,442 (+)MAPPERmRatBN7.2
mRatBN7.2X107,589,713 - 107,589,896 (+)MAPPERmRatBN7.2
Rnor_6.0X115,270,488 - 115,270,670NCBIRnor6.0
Rnor_6.05173,077,208 - 173,077,610NCBIRnor6.0
Rnor_5.05176,552,922 - 176,553,324UniSTSRnor5.0
Rnor_5.0X113,722,731 - 113,722,913UniSTSRnor5.0
RGSC_v3.45172,485,313 - 172,485,715UniSTSRGSC3.4
RGSC_v3.4X34,505,206 - 34,505,388UniSTSRGSC3.4
CeleraX106,987,457 - 106,987,639UniSTS
Celera5164,438,965 - 164,439,367UniSTS
RH 3.4 Map51145.9UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic MapXq14UniSTS
RH136644  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,216,802 - 166,216,998 (+)MAPPERmRatBN7.2
Rnor_6.05173,055,972 - 173,056,167NCBIRnor6.0
Rnor_5.05176,531,686 - 176,531,881UniSTSRnor5.0
RGSC_v3.45172,464,962 - 172,465,157UniSTSRGSC3.4
Celera5164,417,840 - 164,418,035UniSTS
RH 3.4 Map51146.2UniSTS
Cytogenetic Map5q36UniSTS
RH141852  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85171,526,710 - 171,526,987 (+)Marker Load Pipeline
mRatBN7.25166,244,449 - 166,244,726 (+)MAPPERmRatBN7.2
Rnor_6.05173,083,617 - 173,083,893NCBIRnor6.0
Rnor_5.05176,559,331 - 176,559,607UniSTSRnor5.0
RGSC_v3.45172,491,636 - 172,491,912UniSTSRGSC3.4
Celera5164,445,374 - 164,445,650UniSTS
RH 3.4 Map51144.9UniSTS
Cytogenetic Map5q36UniSTS
MARC_5059-5060:996690096:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,238,085 - 166,238,696 (+)MAPPERmRatBN7.2
mRatBN7.2X107,589,759 - 107,590,068 (+)MAPPERmRatBN7.2
Rnor_6.0X115,270,534 - 115,270,842NCBIRnor6.0
Rnor_6.05173,077,254 - 173,077,864NCBIRnor6.0
Rnor_5.05176,552,968 - 176,553,578UniSTSRnor5.0
Rnor_5.0X113,722,777 - 113,723,085UniSTSRnor5.0
RGSC_v3.4X34,505,034 - 34,505,342UniSTSRGSC3.4
RGSC_v3.45172,485,359 - 172,485,969UniSTSRGSC3.4
Celera5164,439,011 - 164,439,621UniSTS
CeleraX106,987,503 - 106,987,811UniSTS
Cytogenetic MapXq14UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_145766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA817907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY544650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY556124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EX490221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM031851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM044847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L24388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000023274   ⟹   ENSRNOP00000023274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5171,495,776 - 171,521,140 (+)Ensembl
mRatBN7.2 Ensembl5166,212,829 - 166,238,876 (+)Ensembl
Rnor_6.0 Ensembl5173,052,063 - 173,078,046 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000050188   ⟹   ENSRNOP00000039105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5171,495,972 - 171,521,145 (+)Ensembl
mRatBN7.2 Ensembl5166,212,831 - 166,238,875 (+)Ensembl
Rnor_6.0 Ensembl5173,066,957 - 173,077,928 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000160153   ⟹   ENSRNOP00000100557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5171,510,160 - 171,521,145 (+)Ensembl
RefSeq Acc Id: NM_145766   ⟹   NP_665709
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,152 - 171,521,143 (+)NCBI
mRatBN7.25166,212,890 - 166,238,881 (+)NCBI
Rnor_6.05173,052,063 - 173,078,049 (+)NCBI
Rnor_5.05176,527,409 - 176,553,763 (+)NCBI
RGSC_v3.45172,459,111 - 172,486,012 (+)RGD
Celera5164,414,228 - 164,439,806 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239529   ⟹   XP_006239591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,879 - 171,521,143 (+)NCBI
mRatBN7.25166,212,761 - 166,238,883 (+)NCBI
Rnor_6.05173,051,900 - 173,078,049 (+)NCBI
Rnor_5.05176,527,409 - 176,553,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239530   ⟹   XP_006239592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,777 - 171,521,143 (+)NCBI
mRatBN7.25166,213,514 - 166,238,883 (+)NCBI
Rnor_6.05173,052,718 - 173,078,049 (+)NCBI
Rnor_5.05176,527,409 - 176,553,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239531   ⟹   XP_006239593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,042 - 171,521,143 (+)NCBI
mRatBN7.25166,212,761 - 166,238,883 (+)NCBI
Rnor_6.05173,051,900 - 173,078,049 (+)NCBI
Rnor_5.05176,527,409 - 176,553,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109290   ⟹   XP_038965218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,782 - 171,521,143 (+)NCBI
mRatBN7.25166,212,761 - 166,238,883 (+)NCBI
RefSeq Acc Id: XM_039109293   ⟹   XP_038965221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,504,409 - 171,521,143 (+)NCBI
mRatBN7.25166,221,966 - 166,238,883 (+)NCBI
RefSeq Acc Id: XM_039109294   ⟹   XP_038965222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,500,583 - 171,521,143 (+)NCBI
mRatBN7.25166,218,322 - 166,238,883 (+)NCBI
RefSeq Acc Id: XM_039109295   ⟹   XP_038965223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,509,645 - 171,521,143 (+)NCBI
mRatBN7.25166,227,380 - 166,238,883 (+)NCBI
RefSeq Acc Id: XM_063287178   ⟹   XP_063143248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,782 - 171,521,143 (+)NCBI
RefSeq Acc Id: XM_063287179   ⟹   XP_063143249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,042 - 171,521,143 (+)NCBI
RefSeq Acc Id: NP_665709   ⟸   NM_145766
- UniProtKB: D4A3G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239591   ⟸   XM_006239529
- Peptide Label: isoform X3
- UniProtKB: D3ZML3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239593   ⟸   XM_006239531
- Peptide Label: isoform X3
- UniProtKB: D3ZML3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239592   ⟸   XM_006239530
- Peptide Label: isoform X3
- UniProtKB: D3ZML3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023274   ⟸   ENSRNOT00000023274
Ensembl Acc Id: ENSRNOP00000039105   ⟸   ENSRNOT00000050188
RefSeq Acc Id: XP_038965218   ⟸   XM_039109290
- Peptide Label: isoform X2
- UniProtKB: A6IUR2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965222   ⟸   XM_039109294
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038965221   ⟸   XM_039109293
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038965223   ⟸   XM_039109295
- Peptide Label: isoform X7
- UniProtKB: P46892 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063143249   ⟸   XM_063287179
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063143248   ⟸   XM_063287178
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000100557   ⟸   ENSRNOT00000160153
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P46892-F1-model_v2 AlphaFold P46892 1-436 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694322
Promoter ID:EPDNEW_R4847
Type:initiation region
Name:Cdk11b_1
Description:cyclin-dependent kinase 11B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05173,052,015 - 173,052,075EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628604 AgrOrtholog
BioCyc Gene G2FUF-38917 BioCyc
Ensembl Genes ENSRNOG00000017213 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000023274 ENTREZGENE
  ENSRNOT00000050188 ENTREZGENE
  ENSRNOT00000160153 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro CDK UniProtKB/Swiss-Prot
  CDK11/PITSLRE_STKc UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
NCBI Gene 252879 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/Swiss-Prot
  CYCLIN-DEPENDENT KINASE 11A-RELATED UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Cdk11b PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017213 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt A0ABK0LGE8_RAT UniProtKB/TrEMBL
  A6IUR2 ENTREZGENE, UniProtKB/TrEMBL
  CD11B_RAT UniProtKB/Swiss-Prot
  D3ZML3 ENTREZGENE, UniProtKB/TrEMBL
  D4A3G2 ENTREZGENE, UniProtKB/TrEMBL
  P46892 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-02-22 Cdk11b  cyclin-dependent kinase 11B  Cdc2l1  cell division cycle 2 homolog (S.pombe)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Cdc2l1  cell division cycle 2 homolog (S.pombe)-like 1      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Cdc2l1  cell division cycle 2 homolog (S.pombe)-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL