Kcnj2 (potassium inwardly-rectifying channel, subfamily J, member 2) - Rat Genome Database

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Gene: Kcnj2 (potassium inwardly-rectifying channel, subfamily J, member 2) Mus musculus
Analyze
Symbol: Kcnj2
Name: potassium inwardly-rectifying channel, subfamily J, member 2
RGD ID: 62261
MGI Page MGI
Description: Enables identical protein binding activity. Acts upstream of or within cardiac muscle cell action potential and magnesium ion transport. Predicted to be located in several cellular components, including T-tubule; dendritic spine; and intercalated disc. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in glutamatergic synapse and postsynaptic membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Orthologous to human KCNJ2 (potassium inwardly rectifying channel subfamily J member 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: inward rectifier K(+) channel Kir2.1; inward rectifier potassium channel 2; IR; IRK-1; IRK1; Kcnf; Kcnf1; Kir2; Kir2.1; potassium channel, inwardly rectifying subfamily J member 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911110,956,990 - 110,967,651 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11110,956,990 - 110,967,647 (+)EnsemblGRCm39 Ensembl
GRCm3811111,066,164 - 111,076,825 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11111,066,164 - 111,076,821 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711110,927,478 - 110,938,139 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611110,882,254 - 110,891,741 (+)NCBIMGSCv36mm8
Celera11122,816,654 - 122,827,315 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1175.23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-dichloroaniline  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
5-aza-2'-deoxycytidine  (EXP)
acetamide  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
atenolol  (ISO)
barium chloride  (ISO)
barium(0)  (EXP,ISO)
belinostat  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butan-1-ol  (ISO)
cadmium dichloride  (ISO)
clofibrate  (EXP)
crocidolite asbestos  (ISO)
daunorubicin  (ISO)
diallyl disulfide  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
halothane  (EXP)
lipopolysaccharide  (EXP)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mitoxantrone  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitroprusside  (ISO)
paracetamol  (EXP,ISO)
phenethyl caffeate  (ISO)
phenylmercury acetate  (ISO)
potassium atom  (EXP,ISO)
propranolol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
tribromoethanol  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
neuron-to-neuron signaling pathway via the chemical synapse  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Novel KCNJ2 mutation in familial periodic paralysis with ventricular dysrhythmia. Ai T, etal., Circulation. 2002 Jun 4;105(22):2592-4.
2. Mesenchymal stem cell transplantation mitigates electrophysiological remodeling in a rat model of myocardial infarction. Lai PF, etal., J Cardiovasc Electrophysiol. 2013 Jul;24(7):813-21. doi: 10.1111/jce.12162. Epub 2013 May 3.
3. MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation. Luo X, etal., J Clin Invest. 2013 May 1;123(5):1939-51. doi: 10.1172/JCI62185. Epub 2013 Apr 1.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Characterization of the murine mafF gene. Onodera K, etal., J Biol Chem 1999 Jul 23;274(30):21162-9.
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. Differential distribution of individual subunits of strongly inwardly rectifying potassium channels (Kir2 family) in rat brain. Pruss H, etal., Brain Res Mol Brain Res. 2005 Sep 13;139(1):63-79.
12. Mouse MP Annotation Import Pipeline RGD automated import pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23. Sagane K, etal., Gene 1999 Aug 5;236(1):79-86.
Additional References at PubMed
PMID:1879353   PMID:7580148   PMID:7680768   PMID:7696590   PMID:7707353   PMID:7917304   PMID:8189383   PMID:8282096   PMID:8595891   PMID:8647266   PMID:8799888   PMID:9226367  
PMID:9261131   PMID:9271675   PMID:9367675   PMID:9533862   PMID:9712915   PMID:10349636   PMID:10479680   PMID:10904001   PMID:10920230   PMID:11042159   PMID:11076861   PMID:11181181  
PMID:11217851   PMID:11287423   PMID:11410627   PMID:11809752   PMID:11906215   PMID:12203395   PMID:12369836   PMID:12477932   PMID:12573259   PMID:12689816   PMID:12740427   PMID:12893283  
PMID:12923176   PMID:12923194   PMID:15024025   PMID:15271672   PMID:15304346   PMID:15304517   PMID:15311931   PMID:15459242   PMID:15581370   PMID:15747579   PMID:15824191   PMID:15880743  
PMID:16141072   PMID:16141073   PMID:16571646   PMID:16602821   PMID:16834334   PMID:16985003   PMID:16996082   PMID:17437338   PMID:17473172   PMID:17546530   PMID:17640933   PMID:17699636  
PMID:17890431   PMID:18004877   PMID:18276733   PMID:18319624   PMID:19421833   PMID:19561601   PMID:20045730   PMID:20568224   PMID:20798526   PMID:20962011   PMID:21143561   PMID:21267068  
PMID:21511879   PMID:21677750   PMID:21703452   PMID:21732368   PMID:21873635   PMID:22348965   PMID:22496522   PMID:22509027   PMID:22772332   PMID:22949619   PMID:23085334   PMID:23625347  
PMID:23671115   PMID:24249731   PMID:24259419   PMID:24633623   PMID:24687990   PMID:25472961   PMID:26321200   PMID:26378152   PMID:26520451   PMID:26627720   PMID:26840527   PMID:26869275  
PMID:27180262   PMID:27380411   PMID:27560040   PMID:27598576   PMID:27696527   PMID:27699887   PMID:27706140   PMID:28148533   PMID:28319610   PMID:28464250   PMID:28646025   PMID:29018970  
PMID:29502106   PMID:30084828   PMID:30203408   PMID:31349969   PMID:31358994   PMID:32220118   PMID:32554809   PMID:32601236   PMID:32698687   PMID:32810216   PMID:32883967   PMID:32931337  
PMID:33669857   PMID:33875602   PMID:34784737   PMID:34820829   PMID:35694964   PMID:35831953   PMID:36909282   PMID:37353105   PMID:38448811  


Genomics

Comparative Map Data
Kcnj2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911110,956,990 - 110,967,651 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11110,956,990 - 110,967,647 (+)EnsemblGRCm39 Ensembl
GRCm3811111,066,164 - 111,076,825 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11111,066,164 - 111,076,821 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711110,927,478 - 110,938,139 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611110,882,254 - 110,891,741 (+)NCBIMGSCv36mm8
Celera11122,816,654 - 122,827,315 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1175.23NCBI
KCNJ2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381770,169,532 - 70,180,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1770,168,673 - 70,180,044 (+)EnsemblGRCh38hg38GRCh38
GRCh371768,165,673 - 68,176,185 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361765,677,271 - 65,687,780 (+)NCBINCBI36Build 36hg18NCBI36
Build 341765,677,270 - 65,687,776NCBI
Celera1764,737,556 - 64,748,065 (+)NCBICelera
Cytogenetic Map17q24.3NCBI
HuRef1763,551,441 - 63,561,946 (+)NCBIHuRef
CHM1_11768,231,773 - 68,242,282 (+)NCBICHM1_1
T2T-CHM13v2.01771,047,853 - 71,058,363 (+)NCBIT2T-CHM13v2.0
Kcnj2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81096,560,225 - 96,570,788 (+)NCBIGRCr8
mRatBN7.21096,060,834 - 96,071,397 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1096,060,821 - 96,071,445 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10101,129,119 - 101,130,402 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010100,592,089 - 100,593,372 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01096,000,266 - 96,001,549 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01099,429,337 - 99,442,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1099,437,436 - 99,439,114 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01099,125,234 - 99,134,077 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410100,574,985 - 100,576,268 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110100,589,354 - 100,590,638 (+)NCBI
Celera1094,712,069 - 94,713,352 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Kcnj2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554782,734,795 - 2,745,217 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554782,734,795 - 2,745,217 (-)NCBIChiLan1.0ChiLan1.0
KCNJ2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21986,190,439 - 86,213,932 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11791,011,394 - 91,039,851 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01764,097,908 - 64,112,914 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11769,482,344 - 69,492,838 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1769,487,846 - 69,489,129 (+)Ensemblpanpan1.1panPan2
KCNJ2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1916,468,938 - 16,475,722 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl916,468,938 - 16,475,722 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha917,360,013 - 17,366,796 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0918,122,955 - 18,129,749 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl918,122,955 - 18,129,749 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1917,067,115 - 17,073,888 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0910,461,025 - 10,467,799 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0910,426,806 - 10,433,589 (-)NCBIUU_Cfam_GSD_1.0
Kcnj2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056029,949,176 - 9,968,112 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366553,447,321 - 3,458,312 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366553,447,026 - 3,459,569 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNJ2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1210,351,699 - 10,362,244 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11210,351,959 - 10,380,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KCNJ2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11651,448,821 - 51,461,801 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1651,452,567 - 51,453,850 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607722,340,093 - 22,354,971 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnj2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624801365,361 - 374,487 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624801365,393 - 375,802 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kcnj2
399 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1221
Count of miRNA genes:592
Interacting mature miRNAs:754
Transcripts:ENSMUST00000042970
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100058103121973369Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100254186120887165Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse
14700693Ppiq12_mprepulse inhibition QTL 12 (mouse)11101504820114472363Mouse
14700694Ppiq13_mprepulse inhibition QTL 13 (mouse)11101504820114472363Mouse
14700695Ppiq14_mprepulse inhibition QTL 14 (mouse)11101504820114472363Mouse
14700696Ppiq15_mprepulse inhibition QTL 15 (mouse)11101504820114472363Mouse
1300957Pbd1_mpeak bone density 1 (mouse)Not determined11102344123112384123Mouse
4141612Cia40_mcollagen induced arthritis 40 (mouse)Not determined11103273992115021444Mouse

Markers in Region
Kcnj2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811111,073,256 - 111,073,450UniSTSGRCm38
MGSCv3711110,934,570 - 110,934,764UniSTSGRCm37
Celera11122,823,746 - 122,823,940UniSTS
Cytogenetic Map11E2UniSTS
cM Map1168.0UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000042970   ⟹   ENSMUSP00000037192
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11110,956,990 - 110,967,647 (+)Ensembl
GRCm38.p6 Ensembl11111,066,164 - 111,076,821 (+)Ensembl
RefSeq Acc Id: NM_008425   ⟹   NP_032451
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911110,956,990 - 110,967,651 (+)NCBI
GRCm3811111,066,164 - 111,076,825 (+)ENTREZGENE
MGSCv3711110,927,478 - 110,938,139 (+)RGD
Celera11122,816,654 - 122,827,315 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032451   ⟸   NM_008425
- UniProtKB: P35561 (UniProtKB/Swiss-Prot),   Q543W5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000037192   ⟸   ENSMUST00000042970
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35561-F1-model_v2 AlphaFold P35561 1-428 view protein structure

Promoters
RGD ID:6821141
Promoter ID:MM_KWN:10415
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_008425
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611110,927,206 - 110,927,706 (+)MPROMDB
RGD ID:8677228
Promoter ID:EPDNEW_M16643
Type:multiple initiation site
Name:Kcnj2_1
Description:Mus musculus potassium inwardly-rectifying channel, subfamilyJ, member 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16644  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811111,066,164 - 111,066,224EPDNEW
RGD ID:8677226
Promoter ID:EPDNEW_M16644
Type:single initiation site
Name:Kcnj2_2
Description:Mus musculus potassium inwardly-rectifying channel, subfamilyJ, member 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16643  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811111,069,566 - 111,069,626EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104744 AgrOrtholog
Ensembl Genes ENSMUSG00000041695 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000042970 ENTREZGENE
  ENSMUST00000042970.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1400 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRK_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir2.1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_cyto UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kir_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16518 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:104744 ENTREZGENE
NCBI Gene 16518 ENTREZGENE
PANTHER PTHR11767 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11767:SF43 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IRK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRK_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRK_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB KCNJ2 RGD
PhenoGen Kcnj2 PhenoGen
PIRSF GIRK_kir UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS KIR21CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KIRCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt KCNJ2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q543W5 ENTREZGENE, UniProtKB/TrEMBL