St8sia4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4) - Rat Genome Database

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Advanced Search (OLGA)
Gene: St8sia4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4) Rattus norvegicus
Analyze
Symbol: St8sia4
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
RGD ID: 621845
Description: Predicted to enable alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. Predicted to be involved in several processes, including ganglioside biosynthetic process; protein glycosylation; and sialylation. Predicted to be located in Golgi apparatus. Orthologous to human ST8SIA4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; LOC501189; polysialyltransferase; sialyltransferase 8 (alpha-2 8-polysialyltransferase) D; sialyltransferase 8 (alpha-2 8-polysialytransferase) D; sialyltransferase 8 (alpha-2, 8-polysialyltransferase) D; sialyltransferase 8 (alpha-2, 8-polysialytransferase) D; sialyltransferase 8 (alpha-2, 8-sialytransferase) D; Siat8d; similar to CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (Alpha-2,8-sialyltransferase 8D) (ST8Sia IV) (Polysialyltransferase-1); ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89103,437,479 - 103,532,008 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9103,437,479 - 103,532,008 (-)EnsemblGRCr8
mRatBN7.2995,990,131 - 96,084,661 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl995,993,503 - 96,084,653 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9104,418,401 - 104,506,720 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09109,546,381 - 109,634,675 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09107,889,761 - 107,978,055 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09103,117,705 - 103,207,154 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9103,117,506 - 103,207,190 (-)Ensemblrn6Rnor6.0
Rnor_5.09102,730,314 - 102,820,638 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4994,906,912 - 94,921,189 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera993,466,037 - 93,556,487 (-)NCBICelera
RGSC_v3.1995,116,392 - 95,130,395 (-)NCBI
Cytogenetic Map9q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-butoxyethanol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chrysene  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dimethylarsinic acid  (EXP,ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
gamma-aminobutyric acid  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
hydrogen cyanide  (ISO)
L-methionine  (ISO)
lead(II) chloride  (EXP)
malathion  (ISO)
mercury dibromide  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
permethrin  (ISO)
Phenoxybenzamine  (EXP)
phenylmercury acetate  (ISO)
potassium cyanide  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
succimer  (ISO)
testosterone  (EXP)
tetraphene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Developmental expression of two rat sialyltransferases that modify the neural cell adhesion molecule, N-CAM. Phillips GR, etal., Brain Res Dev Brain Res 1997 Sep 20;102(2):143-55.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8690732   PMID:10766765   PMID:17176637   PMID:18811928   PMID:24753009   PMID:26844880  


Genomics

Comparative Map Data
St8sia4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89103,437,479 - 103,532,008 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9103,437,479 - 103,532,008 (-)EnsemblGRCr8
mRatBN7.2995,990,131 - 96,084,661 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl995,993,503 - 96,084,653 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9104,418,401 - 104,506,720 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09109,546,381 - 109,634,675 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09107,889,761 - 107,978,055 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09103,117,705 - 103,207,154 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9103,117,506 - 103,207,190 (-)Ensemblrn6Rnor6.0
Rnor_5.09102,730,314 - 102,820,638 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4994,906,912 - 94,921,189 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera993,466,037 - 93,556,487 (-)NCBICelera
RGSC_v3.1995,116,392 - 95,130,395 (-)NCBI
Cytogenetic Map9q36NCBI
ST8SIA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385100,806,933 - 100,903,282 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5100,806,933 - 100,903,285 (-)Ensemblhg38GRCh38
GRCh375100,142,637 - 100,238,986 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365100,170,803 - 100,266,869 (-)NCBIBuild 36Build 36hg18NCBI36
Celera596,090,286 - 96,186,603 (-)NCBICelera
Cytogenetic Map5q21.1NCBI
HuRef595,325,564 - 95,421,873 (-)NCBIHuRef
CHM1_1599,575,254 - 99,671,608 (-)NCBICHM1_1
T2T-CHM13v2.05101,315,265 - 101,411,539 (-)NCBIT2T-CHM13v2.0
St8sia4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,515,407 - 95,595,473 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,515,407 - 95,595,296 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38195,587,682 - 95,667,717 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,587,682 - 95,667,571 (-)Ensemblmm10GRCm38
MGSCv37197,484,259 - 97,564,171 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36197,418,088 - 97,498,000 (-)NCBIMGSCv36mm8
Celera198,446,247 - 98,525,617 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.76NCBI
St8sia4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541812,590,536 - 12,679,677 (+)Ensembl
ChiLan1.0NW_00495541812,590,744 - 12,679,677 (+)NCBIChiLan1.0ChiLan1.0
ST8SIA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2496,050,730 - 96,154,130 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1594,204,377 - 94,307,777 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0596,125,853 - 96,225,309 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15101,795,939 - 101,891,031 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5101,795,939 - 101,891,029 (-)EnsemblpanPan2panpan1.1
ST8SIA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.139,708,130 - 9,801,547 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl39,708,173 - 9,845,015 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha311,052,526 - 11,145,589 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.039,598,806 - 9,691,905 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl39,598,845 - 9,691,509 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.139,541,421 - 9,634,114 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.039,562,092 - 9,655,545 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.039,716,870 - 9,809,937 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
St8sia4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213165,085,314 - 165,180,252 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365233,270,718 - 3,365,668 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365233,270,776 - 3,363,114 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST8SIA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2106,754,701 - 106,845,830 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12106,754,831 - 106,845,806 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22110,733,646 - 110,825,844 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ST8SIA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1234,324,886 - 4,423,253 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl234,325,373 - 4,423,109 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660369,963,602 - 10,062,470 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
St8sia4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474319,228,696 - 19,313,243 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474319,225,065 - 19,313,177 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
St8sia4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14166,106,007 - 166,195,828 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in St8sia4
645 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:21
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000026010
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)986720043110356905Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)985262459109044727Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat

Markers in Region
BE106499  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2995,993,553 - 95,993,723 (+)MAPPERmRatBN7.2
Rnor_6.09103,117,109 - 103,117,278NCBIRnor6.0
Rnor_5.09102,729,718 - 102,729,887UniSTSRnor5.0
RGSC_v3.4994,860,118 - 94,860,287UniSTSRGSC3.4
Celera993,465,441 - 93,465,610UniSTS
RH 3.4 Map9815.4UniSTS
Cytogenetic Map9q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 355 192 11 144 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000026010   ⟹   ENSRNOP00000026010
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9103,437,479 - 103,532,008 (-)Ensembl
mRatBN7.2 Ensembl995,993,503 - 96,084,653 (-)Ensembl
Rnor_6.0 Ensembl9103,117,506 - 103,207,190 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000163941   ⟹   ENSRNOP00000109798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9103,437,479 - 103,530,459 (-)Ensembl
RefSeq Acc Id: NM_053914   ⟹   NP_446366
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89103,437,479 - 103,532,008 (-)NCBI
mRatBN7.2995,990,131 - 96,084,661 (-)NCBI
Rnor_6.09103,117,705 - 103,207,154 (-)NCBI
Rnor_5.09102,730,314 - 102,820,638 (-)NCBI
RGSC_v3.4994,820,275 - 94,859,691 (+)RGD
Celera993,466,037 - 93,556,487 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446366 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB49989 (Get FASTA)   NCBI Sequence Viewer  
  CAL91579 (Get FASTA)   NCBI Sequence Viewer  
  EDL91890 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000026010.5
  ENSRNOP00000109798
  ENSRNOP00000109798.1
RefSeq Acc Id: NP_446366   ⟸   NM_053914
- Peptide Label: precursor
- UniProtKB: O08563 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026010   ⟸   ENSRNOT00000026010
Ensembl Acc Id: ENSRNOP00000109798   ⟸   ENSRNOT00000163941

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A1KQY6-F1-model_v2 AlphaFold A1KQY6 1-454 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696887
Promoter ID:EPDNEW_R7411
Type:multiple initiation site
Name:St8sia4_1
Description:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.09103,207,198 - 103,207,258EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621845 AgrOrtholog
BioCyc Gene G2FUF-26609 BioCyc
Ensembl Genes ENSRNOG00000019128 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026010.8 UniProtKB/TrEMBL
  ENSRNOT00000163941 ENTREZGENE
  ENSRNOT00000163941.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1480.20 UniProtKB/TrEMBL
InterPro Glyco_trans_29 UniProtKB/TrEMBL
  Glycosyltr_29_Sialyltrsf UniProtKB/TrEMBL
  GT29-like_sf UniProtKB/TrEMBL
  Sialyl_trans UniProtKB/TrEMBL
KEGG Report rno:116696 UniProtKB/TrEMBL
NCBI Gene 116696 ENTREZGENE
PANTHER ALPHA-2,8-SIALYLTRANSFERASE UniProtKB/TrEMBL
  CMP-N-ACETYLNEURAMINATE-POLY-ALPHA-2,8-SIALYLTRANSFERASE UniProtKB/TrEMBL
Pfam Glyco_transf_29 UniProtKB/TrEMBL
PhenoGen St8sia4 PhenoGen
PIRSF Sialyl_trans UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019128 RatGTEx
UniProt A0A9K3Y707_RAT UniProtKB/TrEMBL
  A0ABK0LG79_RAT UniProtKB/TrEMBL
  A1KQY6_RAT UniProtKB/TrEMBL
  O08563 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1MA57 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-05 St8sia4  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4  St8sia4  ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-15 St8sia4  ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 4  St8sia4  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-24 St8sia4  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4  LOC501189  similar to CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (Alpha-2,8-sialyltransferase 8D) (ST8Sia IV) (Polysialyltransferase-1)  Data merged from RGD:1590766 737654 APPROVED
2015-11-24 St8sia4  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4  St8sia4  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4  Type changed (type changed from [null] to [protein-coding]) 629549 APPROVED
2006-11-20 LOC501189  similar to CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (Alpha-2,8-sialyltransferase 8D) (ST8Sia IV) (Polysialyltransferase-1)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 St8sia4  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4  Siat8d  sialyltransferase 8 (alpha-2, 8-sialytransferase) D  Symbol and Name updated 1299863 APPROVED
2005-01-20 Siat8d  sialyltransferase 8 (alpha-2, 8-sialytransferase) D    sialyltransferase 8 (alpha-2, 8-polysialytransferase) D  Name updated 1299863 APPROVED
2002-08-07 Siat8d  sialyltransferase 8 (alpha-2, 8-polysialytransferase) D      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression brain expression is restricted to hippocampus and olfactory system 634043
gene_expression high expression in nervous system at embryonic stage 634043